Journal articles on the topic 'Human rights consulting'
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Creel, Eileen L., and Jennifer C. Robinson. "Ethics in independent nurse consulting: Strategies for avoiding ethical quicksand." Nursing Ethics 17, no. 6 (November 2010): 769–76. http://dx.doi.org/10.1177/0969733010379179.
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Changes in health care have created a variety of new roles and opportunities for nurses in advanced practice. One of these changes is the increasing number of advanced practice nurses carrying out independent consultation. Differences in goals between business and health care may create ethical dilemmas for nurse consultants. The purpose of this article is to describe possible ethical pitfalls that nurse consultants may encounter and strategies to prevent or solve these dilemmas. Three themes related to nursing codes of ethics will be discussed: the duty to uphold human rights, the duty to fulfill commitments, and the duty to practice the profession competently.
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Richter, Ansgar, and Katrin Schröder. "Determinants and performance effects of the allocation of ownership rights in consulting firms." Journal of Organizational Behavior 29, no. 8 (November 2008): 1049–74. http://dx.doi.org/10.1002/job.555.
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Friedman, Elisabeth Jay. "Constructing “The Same Rights with the Same Names”: The Impact of Spanish Norm Diffusion on Marriage Equality in Argentina." Latin American Politics and Society 54, no. 4 (2012): 29–59. http://dx.doi.org/10.1111/j.1548-2456.2012.00171.x.
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AbstractThis article argues that Spain has been the driving external force in the advancement of LGBT rights in Latin America, from marriage in Argentina to the regional recognition of “sexual diversity rights” as human rights. Acting as “norm entrepreneurs,” Spanish activists and organizations, relying on development aid, have promoted their perspectives through two approaches: strategic consulting and resource transfer. Their diffusion is illustrated primarily by the Argentine case. There, activists underwritten by Spanish resources have borrowed Spanish strategies to achieve “the same rights with the same names.” Besides broadening our understanding of the struggle for LGBT equality in Latin America, this article deepens the explanation of norm diffusion, focusing on emergence. In this stage, specific individuals and organizations deliberately select appropriate “targets” for and moments of intervention. But norm “receptors” must also be ready for action.
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Azmi M., Ulul. "Penerapan Undang Undang Otonomi Daerah No. 32 Tahun 2004 Jo Perda No. 7 Tahun 2006 di Waru Sidoarjo." al-Daulah: Jurnal Hukum dan Perundangan Islam 3, no. 1 (April 1, 2013): 214–40. http://dx.doi.org/10.15642/ad.2013.3.1.214-240.
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Abstract: This article is a field research on the application of the Regional Autonomy Law No. 32 year 2004, jo PERDA (Regional Regulation) No. 7 year 2006 about the local government in Waru-Sidoarjo. The research was conducted by interviewing some people from four villages, namely Ngingas, Kepuh Kiriman, Tambak Oso, and Tambak Rejo. The research concludes that the community of the four villages had been carrying out the mandate of the Regional Autonomy Law No. 32 year 2004, jo PERDA (Regional Regulation) No. 7 year 2006. However, the compliance in carrying out the law is not based on their legal awareness. It is because there are some laws that are considered as discrimination and murder of the rights of individuals, including the prohibition of the village government to take charge of the political party (consulting / comparative study) ". It can, of course, kill the principles of human rights and democracy, whereas the legislation itself gives respect to the principles of democracy and human rights. The principles to be considered in formulating constitution is the guarantee of human rights of each member of society and the equality of all people before the law without any distinctions of social statification.Keywords: Implementation, regional autonomy law, Waru
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Galderisi, S. "Conceptual Aspects of Mental Health in its Intersection with Human Rights and Development." European Psychiatry 41, S1 (April 2017): S8. http://dx.doi.org/10.1016/j.eurpsy.2017.01.075.
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IntroductionImproving mental health of people is an important goal of the present millennium. Community-based services programs for prevention of mental disorders and promotion of mental health have been implemented in several countries. However, the proportion of people suffering from mental disorders is significantly and persistently high, and psychosocial distress due to migration, natural disasters, and terrorism; in general, feeling of insecurity is unlikely to improve current figures.AimsTo highlight the interrelatedness of mental health, development and human rights, in particular in women and girls.MethodsThe presentation will consider conceptual aspects of mental health in its intersection with human rights and development, with particular reference to women and girls.ResultsCurrent definitions of mental health might be misleading and convey the false expectation that mental health coincides with happiness and productivity. An alternative conceptual framework will be presented, in which mental health is a dynamic state of internal equilibrium that enables individuals to use their abilities in harmony with universal values of society. Different factors concur to the dynamic equilibrium, and will be discussed in their intersection with human rights and development, with particular reference to the most frequent violations of human rights (e.g. trafficking, domestic abuse, sexual violence) that contribute to increase the risk of mental disorders in women and girls.ConclusionMental health is rooted in personal development and social context in which the person lives. Strategies aimed to address mental health in women and girls will need to consider gender, country and socio-cultural specificities.Disclosure of interestHonoraria or Advisory board/consulting fees from the following companies: Lundbeck, Janssen Pharmaceuticals, Hoffman-La Roche, Angelini-Acraf, Otsuka, Pierre Fabre and Gedeon-Richter.
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Przyłuska-Fiszer, Alicja. "Etyczne podstawy kontroli genetycznej." Etyka 23 (December 1, 1988): 111–31. http://dx.doi.org/10.14394/etyka.328.
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The purpose of this paper is to examine some beliefs about the ethical justification of negative eugenics, i.e. a policy of limiting the frequency of childbearing by women prone to give birth to children with genetic defects. The main thrust of the paper is to define and defend of a particular duty v i s – á – v i s the future generations, viz. the duty to provide the future persons with healthy genetic endowment. In the first part of the paper the concept of the ‘obligation to future generation’ is considered. In the second part the putative right of children to acquire healthy genetic endowment is critically assessed from the moral point of view. The author focuses on important reservations concerning moral rights of not even potentially existing persona and the subsequent difficulty in establishing when such rights are infringed. The last part of the paper deals with the possibility of justifying our moral obligations to the future generations by consulting our direct moral duties, and bypassing the controversial issues of the rights of non-existent persons. The author concludes: one of the most credible methods of justifying the objectives of negative eugenics is the acceptance of the depersonalized version of the utilitarian principle (also called globally conceived principle of utility) which stipulates that the sum of pain in the world be minimized and the sum of happiness be maximized. In the same vein the traditional concept of the ‘sanctity’ of human life should be revised in the light of the principle that human life presupposes consciousness and dignity. When these two assumptions are made, it can be shown that due to the application of genetic control the future generations will live a happier life and suffer from fewer diseases than they would if we decided to ban genetic control.
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Kujirakwinja, D., A. J. Plumptre, A. Twendilonge, G. Mitamba, L. Mubalama, J. D. D. Wasso, O. Kisumbu, et al. "Establishing the Itombwe Natural Reserve: science, participatory consultations and zoning." Oryx 53, no. 1 (January 18, 2018): 49–57. http://dx.doi.org/10.1017/s0030605317001478.
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AbstractBiological surveys starting in the 1950s provided clear evidence that the Itombwe Massif, located in eastern Democratic Republic of Congo, is one of the most important areas for conservation in Africa. Further surveys in the mid 1990s and early 2000s showed key species were still present and could be conserved. Following a report on these surveys the Ministry of Environment established the Itombwe Reserve in 2006 without consulting local communities who have legitimate customary rights to reside within the area and use the region's natural resources. Although creating the Reserve was within the government's legal authority, its establishment violated the rights of the people there. Here we report over a decade of work by a consortium of international and national human rights and conservation NGOs, the local communities and the protected areas authority (Institut Congolais pour la Conservation de la Nature), to remediate this taking of customary rights. Starting in 2008 these partners began a participatory process with all 550 villages within and around the boundary of the Reserve. Using a community resource use mapping approach, developed from best practices, the team helped communities determine the boundary of the Reserve, and then pilot participatory zoning to identify zones for settlements, agriculture, hunting, gathering of non-timber forest products, and conservation. This process secured the customary rights of long-term residents in the Reserve and protected their lands from being taken by non-rights holders. As a result of this work the use rights of communities were largely restored and the communities agreed on 23 June 2016 to formalize the boundaries of the renamed Itombwe Nature Reserve.
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Stover, Eric, Miranda Sissons, Phuong Pham, and Patrick Vinck. "Justice on hold: accountability and social reconstruction in Iraq." International Review of the Red Cross 90, no. 869 (March 2008): 5–28. http://dx.doi.org/10.1017/s1816383108000064.
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AbstractHaving invaded Iraq without UN Security Council authorization, the United States was unable to convince many countries to take a meaningful role in helping Iraq deal with its violent past. Always insisting that it would “go it alone”, the United States implemented accountability measures without properly consulting the Iraqi people. Nor did the United States access assistance from the United Nations and international human rights organizations, all of which possess considerable knowledge and experience of a wide range of transitional justice mechanisms. In the end, the accountability measures introduced by the Americans either backfired or were hopelessly flawed. What are needed in Iraq are a secure environment and a legitimate authority to implement a comprehensive transitional justice strategy that reflects the needs and priorities of a wide range of Iraqis. Such a strategy should contain several measures, including prosecutions, reparations, a balanced approach to vetting, truth-seeking mechanisms and institutional reform.
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Boda, Dorottya, and László Neumann. "Social dialogue in Hungary and its influence on EU accession." Transfer: European Review of Labour and Research 6, no. 3 (August 2000): 416–33. http://dx.doi.org/10.1177/102425890000600307.
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The paper reviews the positions of the Hungarian social partners on the labour issues relating to EU accession. In addition to the topics dealt with in the 'Social Policy and Employment' chapter in the accession negotiations, the paper also discusses unions' and employers'views on labour migration, as well as how the adaptation of EU regulations in various sectors is likely to affect employment prospects. The paper argues that, on the one hand, social dialogue on EU accession can become more meaningful if employers and unions develop a co-ordinated strategy. On the other hand, appropriate back-up by experts is also required, because social partners ought to influence the complex system of negotiations being conducted, by experts of both the EU Commission and the Hungarian government, behind the scenes of high-level political negotiations. The authors also analyse the operation of social dialogue fora dedicated to EU accession issues. Hungary was the first East European candidate country to establish a joint committee with the Economic and Social Council (ESC), and within the country labour-related issues of accession have been delegated to the newly founded European Integration Council. In these fora the behaviour of trade unions is largely a consequence of the frustration over the fact that the current right-wing coalition government does not wish to go any further than formally observe the unions' consulting rights on major issues. At the same time organisational weakness and internal divisions still exist on the trade union side.
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TARASOVA, MARIA, and IVAN SMIRNOV. "HISTORY OF THE ESTABLISHMENT OF PUBLIC SUPERVISORY COMMISSIONS." History and modern perspectives 2, no. 3 (September 30, 2020): 71–78. http://dx.doi.org/10.33693/2658-4654-2020-2-3-71-78.
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The article deals with the historical aspects of the formation and key periods of development of public monitoring commissions. Consideration of the topic of this article through the prism of events that highlight the prerequisites for the formation of a system of public control, allowed the authors both to identify systematic difficulties faced by individuals who joined human rights organizations, and to formulate specific proposals, the application of which in practice can be indispensable for improving the activities of public monitoring commissions at the current stage of their development. The content of the article reveals historical facts that played an important role in the formation of public monitoring commissions, mainly as a human rights institution of public observers. The authors note some persons who are interested in creating a system of public control that can provide both consulting and financial assistance not only to representatives of penitentiary institutions, but also to citizens held in them. The article allows you to clearly present the chronology of events that are elements of the Foundation of modern human rights organizations, including a description of situations that affected the performance of members of public monitoring commissions in various time periods. The authors attribute the dynamics of the relevance of the functions of public control to various circumstances, including the emergence of the Gulag, which became the main stumbling block in the development of public monitoring commissions at the end of the second half of the XX century. The article also highlights the stages of forming the next composition of public monitoring commissions, provides indicators that characterize not only the number of their members in the subjects of the Russian Federation and members of such commissions, but also the number of visits to places of forced detention, verification activities, complaints and applications considered, legal consultations, etc. In addition, the authors analyzed the activities of human rights organizations that are active in some regions of the Russian Federation, which revealed the specifics of the implementation of certain rights of citizens, including those who are in prison. The use of a systematic approach to the study of the historical aspect of the creation of public monitoring commissions and the analysis of the organization of work of their members allowed the authors to identify certain problems of theoretical and practical significance, as well as to suggest ways to solve them.
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Ribeiro, Gustavo. "Practicing Anthropology in Brazil: A Retrospective Look at two Time Periods." Practicing Anthropology 26, no. 3 (July 1, 2004): 6–10. http://dx.doi.org/10.17730/praa.26.3.m584824n56543k2r.
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Brazilian anthropologists like to think of ourselves as political actors that play a critical role vis-à-vis the State and society in general. This approach reflects the most frequent way Brazilian anthropologists view themselves and their place in Brazilian life and represents the political loci that anthropology has had in the last four decades in Brazil. This "native's point-of-view" means that engaging in politics is the way "applied anthropology" is done in Brazil. This does not imply, however, that applied anthropology does not exist in Brazil in the classic sense of this term. Anthropologists do consulting work for governmental and non-governmental organizations, as well as private corporations. What I submit is that the preferred view, or the prevailing self-image of Brazilian anthropologists, one that is consolidated and disseminated in the Brazilian Anthropological Association (ABA), is that of a critically engaged professional who has historically defended human rights, especially of disenfranchised groups. Interestingly enough, a history of applied anthropology in Brazil is still to be done.
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Setiawan, Ervin. "AUTHORITY OF INTELLECTUAL PROPERTY CONSULTANTS." Yuridika 31, no. 2 (August 24, 2017): 241. http://dx.doi.org/10.20473/ydk.v31i2.4801.
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Intellectual Property Consultants appointed by the Ministry of Law and Human Rights is an office that has a limited authority to carry out their duties; The appointment of IPR consultant are intended to assist Ministry of Law and Human Rights in resolving the matter on IPR registration. Due to the reason that IPR is the scope of Ministry of Law and Human Rights authority, the one which has the authority to appoint someone as IPR Consultant is also Ministry of Law and Human Right. Appointment of IPR Consultant should be specially granted for Law School Graduate due to the reason that Consultant shall understand and able to execute the procedure of authority and regulation that limits its authority in running Consultant position. In carrying out its duties, IPR Consultant will be closely related to legal action and must strictly comply with the Law and assume responsibility given by the client. The duties and responsibilities attached to IPR Consultant have a legal consequence. In conducting its duties, IPR Consultant shall be able to read and implement the regulation enforced by the government.
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Kelly, Brendan D. "Mental Health Policy in Ireland 1984–2004: theory, overview and future directions." Irish Journal of Psychological Medicine 21, no. 2 (June 2004): 61–68. http://dx.doi.org/10.1017/s0790966700008326.
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Recent years have seen renewed emphasis on the importance of mental health policy as a key component of health and social policy at both national and international levels. In 2001 the European Commission produced a public health framework for mental health in the EU. In the same year, the World Health Organisation devoted its annual health report to mental health and called on countries to formulate, update and implement mental health policies. The EU and WHO initiatives both recognised that the challenges facing mental health policy makers are increasingly transnational in scope, related to issues such as rapid demographic change, increased transnational migration, the protection of human rights and the implementation of a growing number of international laws, directives and protocols in relation to mental health care.Significant progress has been made in the development of Irish mental health services over the past 40 years. Nevertheless, many challenges remain. The aims of this paper are to outline:• Prevailing theoretical perspectives on mental health policy• Mental health policy in Ireland since the last major policy revision in 1984• Relevant economic and demographic changes in Ireland since 1984• Relevant clinical, legislative and policy developments in relation to mental health• Future directions for mental health policy.Electronic literature searches were performed using Psyclit (American Psychological Association, 1887–2003), Medline (United States National Library of Medicine, 1985 – 2003), with broad search terms related to mental health policy. Additional books and papers were identified by tracking back through references and consulting with colleagues. Policy documents and selected literature on Irish psychiatric services were reviewed and related to recent literature on mental health policy.
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Tribe, Rachel, and Deanne Bell. "Social justice, diversity and leadership." European Journal of Counselling Psychology 6, no. 1 (October 31, 2018): 111–25. http://dx.doi.org/10.5964/ejcop.v6i1.145.
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This paper will discuss what is meant by social justice in relation to counselling psychology specifically and psychology generally within the UK, as well as briefly considering social justice in the wider context. It will discuss if there is a role for counselling psychologists and psychology in promoting social justice through challenging social inequalities and promoting anti-discriminatory practice. It will review the role of counselling psychology in potentially foregrounding inclusive practice which celebrates diversity and provides leadership on this issue. It will then discuss the possible skills and theories psychologists have at their disposal to undertake work which promotes social justice and equality and takes into consideration human rights. It will provide a range of examples of where psychologists have undertaken social justice work using their training and skills and provided leadership in a range of contexts outside the consulting room. The paper will argue that taking an active leadership role to encourage the promotion of social justice is at the centre of our work as a profession, a division and as individual counselling psychologists. Counselling psychology has traditionally put individual therapeutic work at the centre of training and whilst this work is important, this paper will argue that there are numerous other roles and tasks which psychologists could usefully be involved with. These would help ensure that the requirements of service users/experts by experience (EBE) are met and that the context of their lives are foregrounded at the micro (individual) as well as the macro (contextual) level. This may require counselling psychologists to take a wider holistic or systemic perspective and understanding, advocating or intervening in relation to the structural and contextual issues which may give rise to psychological distress, and thereby promote social justice.
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VIEGAS-LIQUIDATO, Vera Lúcia. "DERECHOS DE LA PERSONA HUMANA: EL DERECHO DEL EXTRANJERO PRIVADO DE LIBERTAD A LA ASISTENCIA CONSULAR." Revista Juridica 2, no. 55 (April 11, 2019): 53. http://dx.doi.org/10.21902/revistajur.2316-753x.v2i55.3384.
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RESUMENEn este trabajo se hará inicialmente una evolución histórica del Derecho Internacional de los Derechos Humanos, tomando el marco teórico referencial de Karel Vasak, Norberto Bobbio y Antonio Augusto Cançado Trindade, para abordar la discusión del derecho internacional de los derechos humanos en generaciones / dimensiones. A continuación se abordarán el estado de arte, límites y desafíos del derecho fundamental del extranjero privado de la libertad a la asistencia consular. Se plantearán cuestiones como, si al privado de la libertad no se le ofreció asistencia consular, qué implicaciones generaría para la garantía del debido proceso legal e incluso la posibilidad de la nulidad de una sentencia penal condenatoria. Se analizará jurisprudencia internacional al respecto, incluida la opinión consultiva de la Corte Interamericana de Derechos Humanos. PALABRAS-CLAVE: Derecho Internacional de los Derechos Humanos; Derechos Fundamentales de la Persona Humana; Derecho a la asistencia consular; Garantías del debido proceso legal. RESUMONeste trabalho far-se-á, inicialmente, uma evolução histórica do direito internacional dos direitos humanos, utilizando-se o referencial teórico de Karel Vasak, Norberto Bobbio e Antonio Augusto Cançado Trindade, para pautar a discussão do direito internacional dos direitos humanos em gerações/dimensões. Em seguida, analisar-seão os desafios, limites, estado de arte, do direito fundamental do preso estrangeiro à assistência consular. Levantar-se-ão questões como, caso ao preso estrangeiro não lhe tenha sido oferecida a assistência consular, as implicações que isso geraria para as garantias do devido processo legal e até mesmo para a nulidade de uma sentença penal condenatória. Considerar-se-á jurisprudência internacional a respeito, incluindo a opinião Consultiva da Corte Interamericana de Direitos Humanos. PALAVRAS-CHAVE: Direito Internacional dos Direitos Humanos; Direitos Fundamentais da Pessoa Humana; Direito à assistência consular; Garantias do devido processo legal. ABSTRACTIn this work, initially, a historical evolution of the international law of the human rights will be made, using the theoretical reference of Karel Vasak, Norberto Bobbio and Antonio Augusto Cançado Trindade, to guide the discussion of international law of the human rights in generations / dimensions. Afterwards, will be analyzed the challenges, limits, state of art, the fundamental right of the foreign detainee to consular assistance. Questions will arise as, if the detainee has not been notified of his right to consular assistance, the implications that this would generate for the guarantees of the due process of law. International law cases will be considered, including the Advisory Opinion of the Inter-American Court of Human Rights. KEYWORDS: International Human Rights Law; Fundamental Rights of the Human Person; Right to consular assistance; Guarantees of the due process of law.
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ZHUK, Valeryi, and Kateryna MELNYK. "SYSTEM OF REPORTING MANAGEMENT SUPPORT: THE PAST AND THE FUTURE." "EСONOMY. FINANСES. MANAGEMENT: Topical issues of science and practical activity", no. 4 (44) (April 2019): 107–16. http://dx.doi.org/10.37128/2411-4413-2019-4-13.
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Since 2017 in the EU, companies with more than 500 staff must be required to report on environmental, social, human rights, corporate governance, combating corruption and bribery, the prospects of innovation development and other information of interest to the public. Such data can have as financial, as well as non-financial nature. In addition, the audit occupies a special place in the reporting system of developed countries. Audit not only ensures the credibility of integrated reporting, but also provides clarification on its compilation. The purpose of the article is to substantiate the conceptual provisions of the formation and development of integrated reporting in Ukraine, taking into account the current world trends, national needs and possibilities of IT technologies. Research methods. The methods and techniques of scientific knowledge are used to formulate the hypothesis of the study and its proof. In particular, The method of induction, deduction and abstraction is used to study the past achievements of the domestic scientific school of accounting for improving the information provision of the management of the national economy and forecasting the development of expanded (integrated) reporting in Ukraine. A systematic analysis of the construction and organization of integrated reporting in Ukraine and the world has been carried out. Due to the simulation using the axiomatic and hypothetical method, the principles and conceptual provisions of developing the accounting and reporting system in the agrarian sector of economy are proposed. Research results. It was found that the dynamics of the number of forms of statistical observation in Ukraine has a stable negative tendency. Problems of unreliability of reporting information in agriculture were revealed. The changes in the legislation related to introduction of integrated reporting in Ukraine were analyzed. According to authors, decentralization as a catalyst for information requests will form a new basis for developing a reporting system. The prospects of integrated reporting on sustainable development of agrarian enterprises of Ukraine were estimated. A specific benchmark for the development of integrated reporting in the agrarian sector can be the Global Strategy for Agricultural and Rural Statistics Development of the United Nations and FAO. The conceptual provisions of the development of the accounting and reporting system of the agrarian sector were proposed. The emphasis is on the role of auditors and consulting companies in the development of integrated reporting. It was proved that the domestic accounting science is able to simulate and conceptually, methodologically and methodically to ensure the development of modern accounting and information system in Ukraine. It is important to take into account the following principles: queries - opportunities; world trends - national interests; behavioral basis - capabilities of IT technologies; regulatory factors - entrepreneurial initiative, etc.
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Teplyakova, O., and A. Sarapulova. "AB0874-HPR TELEMEDICINE CONSULTING IN RHEUMATOLOGY: IDENTIFIED PROBLEMS OF NEW TECHNOLOGY." Annals of the Rheumatic Diseases 80, Suppl 1 (May 19, 2021): 1461.3–1461. http://dx.doi.org/10.1136/annrheumdis-2021-eular.506.
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Background:A feature of healthcare in 2020 was the work in conditions of massive incidence of COVID-19, limited and redistribution of human resources. One of the right decisions in these conditions is to organize schools for patients, which allow simultaneous education and convey the necessary information to a large number of people. The key aspects of the organization of telemedicine schools for patients are presented.Objectives:To assess the feasibility of telemedicine schools for patients as a technology of modern health care in rheumatology.Methods:The work was carried out by the method of a one-stage cross-sectional study of the questionnaire survey of participants of education in rheumatology, conducted in an on-line mode. The number of participants in rheumatology schools was 197 people, the results of the questionnaire were received from 36 respondents. The questionnaire based on the Google platform.Results:10 key principles of organizing online patient education at the present stage were identified: the use of distance technologies, the interest of a medical institution administration, the team approach, the technical possibilities of implementing schools, adaptation of lecture material for patients, the role of a specialized specialist in the educational process, patient participation, measurement efficiency and timely correction, development and improvement of educational technology for patients, desire for cooperation and exchange of experience.Conclusion:The emergence of new opportunities related to online health education of the population, including educational activities for patients, opens up new prospects for improving clinical care aimed at promoting health and preventing disease.Disclosure of Interests:None declared
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Winthrop, Robert. "The Real World: Participation and Other Fictions of Development." Practicing Anthropology 19, no. 4 (September 1, 1997): 35–36. http://dx.doi.org/10.17730/praa.19.4.7324t3565p2jt7x5.
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In December 1996 Theodore Downing, a frequent consultant on development programs and a past president of the Society for Applied Anthropology, filed a human rights complaint against staff of the International Finance Corporation (IFC), the first such complaint ever lodged against an organization of the World Bank Group. In brief, the IFC had retained Dr. Downing to evaluate one aspect of a hydroelectric development project in Chile. His report concerned the project's effects on the indigenous Pehuenche people, and the failure of a foundation established as part of the development scheme to serve their interests. Downing's human rights complaint did not, however, concern the substantive issue of the project's effects on the Pehuenche. Rather, the issue raised by Dr. Downing is that both Pehuenche leaders and community members have been deliberately excluded from any meaningful review of his report because of their ethnicity, and thus prevented from effective involvement in the planning or implementation of the hydroelectric project.
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Hoe, Siu Loon. "What makes a competent change manager? The importance of developing the “right” attitudes." Development and Learning in Organizations: An International Journal 31, no. 5 (September 4, 2017): 14–16. http://dx.doi.org/10.1108/dlo-01-2017-0002.
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Purpose The purpose of this paper is to highlight the importance of developing the “right” attitudes toward change. Design/methodology/approach The viewpoint is based on more than 20 years of experience gained and insights developed through consulting projects and training conducted for numerous multinational companies and public sector organizations across Asia. An overview of international and national competency frameworks that include change management from Australia, United Kingdom, and Singapore is also presented. Findings A competent change manager requires a combination of knowledge, skills, and attitude to effect change. While knowledge and skills have traditionally been emphasized, there is a need to develop the “right” attitude as well. Research limitations This article is based on the author's personal viewpoint which may be subjective. Practical limitations The paper provides researchers with an insight on the importance of attitudes as a key contributing factor to change management competency. For the practitioners, it provides another perspective for designing more effective education programs to train change managers with an emphasis on attitudes. Originality/value This paper contributes to the existing change management literature by providing insights on the importance of competency, in particular, the “right” attitude required of a change manager.
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Seatzu, Francesco. "Civil Society Participation in the Interamerican Development Bank’s Activities and Operations: Enhancing Democratic Accountability?" Spanish Yearbook of International Law Online 17, no. 1 (2013): 43–72. http://dx.doi.org/10.1163/22116125-01701004.
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NGOs and CSOs have progressively enjoyed easy access to, and better possibilities to affect decision-making processes taking place within the Inter-American Development Bank (‘the Bank’ or the ‘IDB’), including also the most recent decisions of the IDB affecting the relationship between Spain and the Latin American and Caribbean (LAC) countries. Indeed, in particular the increasing intensity of NGO and CSO activities and their involvement in the performances and activities of the Bank and of its governing bodies at different levels and stages show that NGOs and CSOs over the last decade have become essential, though often under-recognized components of the operational structures of the internal governance of the IDB. CSOs may be, and often are, eligible to directly receive financings from the Bank. Starting from a brief introduction of the Bank followed by a set of normative arguments on the key accountability challenges facing the IDB Group, the paper will deal with the issue of NGO and CSO participation in relation to the decision-making process on the IDB Group’s financed operations, investment and programmatic lending operations. It will also consider the social and environmental accountability initiatives that derive from the Bank’s core aims of achieving poverty eradication and effective and sustainable development. In doing so, approaching the topic from an international legal perspective, the paper will first explore the broad and inclusive definition of what constitutes a ‘civil society organization’ for the IDB and its affiliated organizations. Secondly, and in more detail, it will consider the “Strategy for Promoting Citizen Participation in Bank Activities” as approved by the IDB Board of Directors in 2004 in order to expand, strengthen and systematize citizen and civil society participation in the Bank’s activities. Thirdly, the paper will focus on the Guidelines for the functioning of the Civil Society Advisory Councils (the ‘Guidelines’). Fourthly, it will describe how NGO and CSO participation is taken into account by the internal instruments of the Bank envisaging citizen and civil society participation in the IDB’s financial activities (including the most recent activities to enhance the trade and investment relationship between Spain and LAC countries). Therefore, the key features and characteristics of the Guidelines that are of special significance to NGO and CSO participation in the decision-making process on the IDB’s financed operations and in furthering the accountability of the Bank to its constituents – such as the criteria for the establishment and participation of CSOs and NGOs, the notification procedure, the meaning of ‘Civil Society Consulting Groups’, the methods for consultations at operational level, the possibilities for civil society groups and movements, including Spanish civil society groups and movements, to increase human rights and democratic accountability – will all be, in turn, the subject of specific analyses. Finally, the paper will conclude with some observations on the social and democratic accountability of the IDB to civil society and non-state actors, referring in particular to the experience of the internal accountability mechanism established by the IDB’s Board of Governors (the Bank’s highest authority) in 1994 – the Independent Investigation Mechanism of the Inter-American Development Bank (the ‘Independent Mechanism’) – that was established with the aim of “increasing the transparency, accountability, and effectiveness” of the Enhancing Democratic Accountability? 45 Bank and recently replaced by the created Independent Consultation and Investigation Mechanism (ICIM) effective on June 30, 2010.
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Lazcoz Moratinos, Guillermo, and Ander Gutiérrez-Solana Journoud. "La invisible situación jurídica de las mujeres para el TEDH ante la maternidad subrogada en la primera opinión consultiva del protocolo No 16 = The invisible legal situation of women for the ECHR to cross border subrogated in the first advisory opinion of protocol No 16." CUADERNOS DE DERECHO TRANSNACIONAL 11, no. 2 (October 1, 2019): 673. http://dx.doi.org/10.20318/cdt.2019.5012.
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Resumen: El TEDH ha inaugurado el procedimiento consultivo enunciado en el Protocolo 16 al CEDH con la emisión de una Opinión Consultiva solicitada por la Cour de Cassation francesa. El TEDH debía afrontar una serie de preguntas sobre los derechos de la mujer contratante de un acuerdo de maternidad subrogada celebrado en el extranjero en lo respectivo a la filiación. Para resolver estas cuestiones era esperable que el TEDH aplicara la perspectiva de género a su labor jurisdiccional, para analizar las consecuencias de la normativa y de su propia jurisprudencia a la luz del derecho antidiscriminatorio, incluso analizando el impacto de estas prácticas sobre las madres gestantes. Sin embargo, el TEDH opta por la vía de la no contestación y la reiteración de doctrina precedente: la obligación de inscribir menores si hay carga genética del hombre contratante y la de encontrar una vía de reconocimiento de la convivencia del menor con la pareja contratante, ignorando el eje de las preguntas formulada por el tribunal francés.Palabras clave: maternidad subrogada internacional, orden público, interés superior del menor, derechos humanos, CEDH.Abstract: The ECHR has opened the consultative procedure enunciated in Protocol 16 to the ECHR with the issuance of an Advisory Opinion requested by the French Cour de Cassation. The ECHR had to face a series of questions on the rights of contracting women of a surrogacy agreement concluded abroad with regard to filiation. To resolve these issues, it was expected that the ECHR applied the gender perspective to its jurisdictional work, to analyze the consequences of the regulations and its own jurisprudence in the light of the anti-discrimination law, including analyzing the impact of these practices on pregnant mothers. However, the ECHR opts for the way of non-contestation and reiteration of precedent doctrine: the obligation to register minors if there is a genetic load of the contracting man and to find a way to recognize the child’s coexistence with the contracting partner, ignoring the object of the questions asked by the French court.Keywords: cross-border surrogacy, public order, best interest of the child, human rights, ECHR.
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Mijangos González, Javier. "La doctrina de la Drittwirkung der Grundrechte en la jurisprudencia de la Corte Interamericana de Derechos Humanos." Teoría y Realidad Constitucional, no. 20 (July 1, 2007): 583. http://dx.doi.org/10.5944/trc.20.2007.6772.
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Through a study of the jurisprudence of the region over the last twenty years, it becomes possible to see that the CIDH has constructed an entire theory about the applicability of fundamental rights in relations between individuals in Latin America. Through this theory it has addressed the most important social problems in contemporary Latin American history, thus contributing to the transition to democracy for many countries in the region. The study will analyze the stages that the jurisprudence of the CIDH has passed through and which have led to the current criteria that this organization uses. The first stage consists of a series of rulings whose common denominator is the analysis of the obligation of respect and vigilance for fundamental rights by the states listed in article 1.1 of the American Convention on Human Rights. This principle, which is ever-present in its jurisprudence, brings the Inter-American Court to approaches that are similar to those proposed by the United States doctrine of state action, as it makes use of a good number of rulings made by the Supreme Court of the United States between 1960 and 1980. In the second stage, the importance originally placed on determining the characteristics of the agent who committed the violation of fundamental rights is replaced by a series of approaches in which the nature of the actual violation itself becomes the focus. In this phase, the Inter-American Court establishes the idea that the fundamental rights listed in the Convention are erga omnes obligations that are imposed not only in relation to the power of the State but also with respect to the actions of third-party individuals. Finally, the third stage in the evolution of the court’s jurisprudence is represented by the most pertinent case in this matter: Opinión Consultiva 18/03, requested by the United Mexican States regarding the legal status of immigrants. This resolution, which has established a trend up until today, definitively establishes the direct effectiveness of the fundamental rights in relations between individuals.
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Jain, Abhimanyu George. "Daragh Murray (ed.) and Elizabeth Wilmshurst, Francoise Hampson, Charles Garraway, Noam Lubell and Dapo Akande (consultant eds), Practitioners’ Guide to Human Rights Law in Armed Conflict." Journal of International Criminal Justice 16, no. 2 (May 1, 2018): 489–90. http://dx.doi.org/10.1093/jicj/mqy019.
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Sitanggang, Hartini Basaria Natasya, and Awang Dharmawan. "Strategi Marketing Hary Tanoesoedibjo dalam Usaha Membangun Personal Branding Politik." Jurnal Penelitian Pers dan Komunikasi Pembangunan 20, no. 1 (June 1, 2016): 49–62. http://dx.doi.org/10.46426/jp2kp.v20i1.43.
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Today, many people have already used new media for doing their activities, includes communicating. The benefits in opening the edges each humans and using the innovating technology makes the new media usually used by citizen. These concerns are used by the politic consultant to promote some political parties or some candidates. HaryTanoesoedibjo is one of media businessman in Indonesia who tries to take his way becoming a politician. To increase his electability in politic, a politic consultant for HaryTanoesoedibjo should be able to know the right strategies for HaryTanoesoedibjo. This study was made to know what strategies are right for HaryTanoesoedibjo. This research was using the 4Ps and PDB analysis. Besides that, this study was also intended to know the right platform for HaryTanoesoedibjo in case for succeed his way for president election. The datas in this study are from the analysis in social media and website that used by HaryTanoesoedibjo and some available literatures.
Keywords: Political Marketing Strategy, New Media, HaryTanoesoedibjo,
ABSTRAK
Kekuatan media baru sebagai sumber informasi politik, tidak lepas dari perkembangannya sudah menjadi media mainsream yang membangun interaktivitas bagi sesama penggunanya. Hal inilah yang dimanfaatkan oleh konsultan politik untuk mempromosikan partai politik atau kandidat perseorangan. Hary Tanoesoedibjo, sebagai salah satu pebisnis media yang memasuki jalan sebagai politisi. Dalam menaikkan popularitasnya di dunia politik, konsultan politik yang dimiliki oleh Hary Tanoesoedibjo berusaha menerapkan strategi marketing politik, karena mengingat Partai Indonesia Raya (Perindo) dan Hary Tanoesoedibjo sendiri terbilang baru dalam panging politik nasional. Studi ini dibuat untuk mengetahui bagaimana strategi marketing politik dari tim Hary Tanoesoedibjo. Penelitian ini menggunakanan konsep product, place, price, promotion, dan segmentation (4PS) dan positioning, differentiation, dan branding (PDB). Selain itu, studi ini juga ditujukan untuk mengetahui bagaimana platform media baru yang digunakan oleh Hary Tanoesoedibjo sebagai ketua Partai Persatuan Indonesia (Perindo).
Kata kunci: Strategi Marketing Politik, Media baru, Hary Tanoesodibjo.
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Haloush, Haitham. "Rethinking traditional approaches of parties' autonomy in construction contracts: decennial liability as a case study." International Journal of Law and Management 62, no. 6 (June 30, 2020): 577–89. http://dx.doi.org/10.1108/ijlma-04-2020-0089.
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Purpose Employers, contractors, subcontractors and engineers often believe that they have a “common language”, which consists of drawings and specifications, notwithstanding that drawings and specifications must be interpreted and understood in their legal context. Accordingly, due to the legal-technical aspects of construction, it is essential that construction contracts should strike the right balance between the interests of all stakeholders. The purpose of this paper is to examine this issue in depth. Design/methodology/approach To examine this issue in depth, this paper is divided into four sections. First, general background on Jordanian construction law. Second, the conformity between the Jordanian law and international federation of consulting engineers (FIDIC) rules. Third, crystallisation of parties autonomy in construction contracts. Fourth, per defects liability in construction contracts as a case study. Findings Construction disputes are not only a legal issue. It is also a technical challenge to which an interdisciplinary body of legal scholars, contractors, engineers and construction experts should respond by setting flexible standards as practices could change faster than rules. Judges in particular are bound to understand the peculiar technical-legal nature of construction disputes. This should be a good starting point for developing case law in the field of construction which is rather limited. In this way, construction case law can be established gradually and cumulatively on a case by case basis. Originality/value As far as the author is aware, the issue of construction contracts in Jordan has not been researched comprehensively before from technical and legal standpoints. This paper represents a first attempt to examine the issues arising in this difficult and important subject.
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Liu, Wei, Nancy Peeters, Guillén Fernández, and Nils Kohn. "Common neural and transcriptional correlates of inhibitory control underlie emotion regulation and memory control." Social Cognitive and Affective Neuroscience 15, no. 5 (May 2020): 523–36. http://dx.doi.org/10.1093/scan/nsaa073.
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Abstract Inhibitory control is crucial for regulating emotions and may also enable memory control. However, evidence for their shared neurobiological correlates is limited. Here, we report meta-analyses of neuroimaging studies on emotion regulation, or memory control and link neural commonalities to transcriptional commonalities using the Allen Human Brain Atlas (AHBA). Based on 95 functional magnetic resonance imaging studies, we reveal a role of the right inferior parietal lobule embedded in a frontal–parietal–insular network during emotion regulation and memory control, which is similarly recruited during response inhibition. These co-activation patterns also overlap with the networks associated with ‘inhibition’, ‘cognitive control’ and ‘working memory’ when consulting the Neurosynth. Using the AHBA, we demonstrate that emotion regulation- and memory control-related brain activity patterns are associated with transcriptional profiles of a specific set of ‘inhibition-related’ genes. Gene ontology enrichment analysis of these ‘inhibition-related’ genes reveal associations with the neuronal transmission and risk for major psychiatric disorders as well as seizures and alcoholic dependence. In summary, this study identified a neural network and a set of genes associated with inhibitory control across emotion regulation and memory control. These findings facilitate our understanding of the neurobiological correlates of inhibitory control and may contribute to the development of brain stimulation and pharmacological interventions.
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Jacobs, Trent. "What To Expect When You’re Expecting Robots." Journal of Petroleum Technology 73, no. 08 (August 1, 2021): 22–29. http://dx.doi.org/10.2118/0821-0022-jpt.
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The market turmoil of 2020 left the upstream industry with diminished ranks, palpable concerns over long-term demand, and mounting pressure to reduce its carbon footprint. This made for what many consider a bullish case, as JPT has reported, for robotics uptake over the course of the decade. But there are reasons to temper expectations. After all, this is the oil and gas industry. The upstream land-scape is as vast as it is specialized. Each silo is a fortress of status quo to which robot developers must dedicate significant time and fortune in conquering. Some are worth the battle, especially in the offshore arena where factors of cost and safety have made this the most active corner of oil and gas robotics. Many other use cases may be worth bypassing. About 70% of the world’s oil and gas supply is produced onshore which, of course, is much more accessible to human operators. That means a robot dog in the Permian Basin has to jump over a much higher bar in order to create value than a robot dog tasked with inspecting a platform in the middle of the Norwegian Sea. Speaking of inspection, this is both the chief strength and upper limit for much of the current generation of robots. The next generation will be asked to fix things. And whatever they can’t do - or are just not the right tool for - look for it to be covered by industrial automation. As a new class of oil and gas robots finds its niche, and fights for investment dollars along the way, here are a few developments to track and points to consider. This Time It’s Different, Right Boss? The upstream sector pulled back from exploring the frontier of robotics and drone technologies in the last decade relative to other industries, but it is now being pulled forward by societal and technological shifts, according to Ed Tovar who runs an Austin-based consulting company, InTechSys, that serves the defense and energy industry.
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Mcinnes, I., G. Rocha, R. E. Higgs, D. Dairaghi, T. Wehrman, E. Wang, Z. Xin, J. Ross Terres, T. Rooney, and P. C. Taylor. "OP0001 BARICITINIB, TOFACITINIB, UPADACITINIB, FILGOTINIB, AND CYTOKINE SIGNALING IN HUMAN LEUKOCYTE SUBPOPULATIONS: AN UPDATED EX-VIVO COMPARISON." Annals of the Rheumatic Diseases 79, Suppl 1 (June 2020): 1–2. http://dx.doi.org/10.1136/annrheumdis-2020-eular.755.
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Background:everal JAKi are now used for the treatment of RA; approved doses include baricitinib (bari) 2- and/or 4-mg QD, tofacitinib (tofa) 5-mg BID, upadacitinib (upa) 15-mg QD. The JAK selectivity these agents is proposed to vary across the class.Objectives:In vitro cellular pharmacology of bari to tofa, upa, and filgotinib (filgo) were compared.Methods:PBMCs from 6 healthy donors were incubated with the JAKis over a 7- to 8-point concentration range. Following cytokine stimulation, levels of pSTAT were measured and IC50 calculated in gated leukocyte subpopulations. Therapeutic dose relevance was assessed using calculated mean concentration-time (CT) profiles over 24 hours for bari 2- and 4-mg QD; tofa 5- and 10-mg BID; upa 15- and 30-mg QD; filgo 100- and 200-mg QD. Average daily % inhibition of pSTAT (%SI) was calculated for each JAKi, cytokine, and cell type; filgo %SI integrated parent drug + metabolite.Results:The cytokines did not signal in all cell types (Figure 1). When signaling was detected, IC50 and %SI for a particular JAKi were generally similar across cell types, with dose-dependent inhibition (Figures 1 & 2). Based on IC50s, upa was most and filgo/metabolite least potent across JAK2/2 or JAK2/TYK2-dependent (IL-3, GM-CSF, G-CSF), JAK1/3-dependent (IL-2, 4, 15, 21), and JAK1/2/TYK2 dependent (IL-6 & 10, IFN-α & γ) signaling pathways.Figure 1.IC50 values (nM) for baricitinib, tofacitinib, upadacitinib, filgotinib (parent and metabolite) in cytokine-stimulated human PBMC preparations. *p<0.01, **p<0.001, ***p<0.0001 vs. bari.Incorporating CT profiles, no agent potently or continuously inhibited an individual cytokine signaling pathway throughout the dosing interval. Comparing bari 4-mg to tofa 5-mg BID, upa 15-mg QD, and filgo 100-mg QD, %SI of JAK2/2 or JAK2/TYK2-dependent cytokines was highest with bari 4-mg and upa. Inhibition of JAK1/2/TYK2 cytokines was highest with bari 4-mg. Inhibition of JAK2/2 or JAK2/TYK2, and of JAK1/3-dependent cytokines was lowest for filgo 100-mg QD. For bari 2-mg QD vs. these other JAKi doses, %SI of JAK2/2 or JAK2/TYK2 was highest with upa followed by bari 2-mg. The highest inhibitors of the JAK1/2/TYK2-dependent cytokines varied by cytokine / cell type though consistently included upa. Inhibition of JAK1/3 was highest for upa and tofa. Across comparisons, filgo 100-mg QD showed the least %SI of JAK2/2 or JAK2/TYK2-dependent, and of JAK1/3-dependent cytokines. Filgo reached the highest levels of %SI among agents only for 200-mg QD vs. lower doses of the other JAKi (for selected JAK1/2/TYK2-dependent cytokines).Conclusion:JAKis display different in vitro pharmacologic profiles which, coupled to their in vivo pharmacokinetics, suggest they modulate distinct cytokine pathways to differing degrees and durations over 24 hours. Ex vivo whole cell assays seem distinct from cell free kinase inhibition assays in determining the overall cytokine modulatory potential of members of the JAKi class.References:[1]McInnes IB, et al. Arthritis Res Ther. 2019 Aug 2;21(1):183Figure 2.Baricitinib, tofacitinib, upadacitinib, filgotinib: calculated average percent daily STAT inhibition for selected cytokines. -p<0.01, --p<0.001, ---p<0.0001 significantly lower compared to bari (vs. 2-mg if left of vertical line “|”, vs. 4-mg if right of vertical line “|”). +p<0.01, ++p<0.001, +++p<0.0001 significantly higher compared to bari (vs. 2-mg if left of vertical line “|”, vs. 4-mg if right of vertical line “|”).Disclosure of Interests:Iain McInnes Grant/research support from: Bristol-Myers Squibb, Celgene, Eli Lilly and Company, Janssen, and UCB, Consultant of: AbbVie, Bristol-Myers Squibb, Celgene, Eli Lilly and Company, Gilead, Janssen, Novartis, Pfizer, and UCB, Guilherme Rocha Shareholder of: Eli Lilly and Company, Employee of: Eli Lilly and Company, Richard E Higgs Shareholder of: Eli Lilly and Company, Employee of: Eli Lilly and Company, Daniel Dairaghi Shareholder of: Eli Lilly and Company, Employee of: Eli Lilly and Company, Thomas Wehrman Shareholder of: An insignificant amount in AbbVie as part of a larger portfolio, Consultant of: Primity Bio Inc. works with many pharmaceutical and biotech companies and provides CRO services., Evan Wang Shareholder of: Eli Lilly and Company, Employee of: Eli Lilly and Company, Zhang Xin Shareholder of: Eli Lilly and Company, Employee of: Eli Lilly and Company, Jorge Ross Terres Shareholder of: Eli Lilly and Company, Employee of: Eli Lilly and Company, Terence Rooney Shareholder of: Eli Lilly and Company, Employee of: Eli Lilly and Company, Peter C. Taylor Grant/research support from: Celgene, Eli Lilly and Company, Galapagos, and Gilead, Consultant of: AbbVie, Biogen, Eli Lilly and Company, Fresenius, Galapagos, Gilead, GlaxoSmithKline, Janssen, Nordic Pharma, Pfizer Roche, and UCB
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Chiocchi, John, Gary Lamph, Paula Slevin, Debra Fisher-Smith, and Mark Sampson. "Can a carer (peer) led psychoeducation programme improve mental health carers well-being, reduce burden and enrich empowerment: a service evaluation study." Journal of Mental Health Training, Education and Practice 14, no. 2 (March 11, 2019): 131–40. http://dx.doi.org/10.1108/jmhtep-10-2018-0057.
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Purpose Carers of people with mental health problems present with high levels of burden, poor mental well-being and feelings of disempowerment by mental health services. The purpose of this paper is to establish whether providing a psychoeducation skill programme for carers would lead to an improvement of mental well-being, reduce the levels of burden that carers sometimes feel while caring for someone with mental illness and also to increase empowerment. This paper provides a service evaluation study of an innovative carer-led psychoeducational intervention that was undertaken. Design/methodology/approach This programme was initiated and led by a carer who had experienced a lack of service provision to support carers and families in understanding and caring for a relative with severe and enduring mental health diagnoses. A model of co-production was adopted with the carer who led this initiative working closely with an occupational therapist and consultant psychologist in its development and delivery. Data were collected to measure the impact of the training at five different time points. The measures employed to measure outcomes were the Warwick-Edinburgh Mental Well-being Scale, the Burden Assessment Scale and Family Empowerment Scale. Findings Results indicated improved well-being, reduced burden and increased family empowerment in carers who completed this peer-led carer initiative psychoeducational programme. Research limitations/implications This service evaluation study was conducted in a single site and in the site in which it was developed. The carer consultant who led this evaluation and development of the intervention was also the peer worker who delivered the interventions. Hence, the authors are unable to ascertain if the results reported are unique to the individual peer worker. The transferability of this programme and generalisability of the result should therefore be treated with caution and further replication of this model and research is required. This would be beneficial to be conducted in an alternative site from where it was developed, delivered by different facilitators and include a control group. Practical implications The evidence from this study indicates that carers are able and willing to attend a group psychoeducational programme. A high number of referrals to the programme in a relatively short timeframe indicates that there is significant demand for such a service. The implementation of the programme is relatively straightforward. The key challenges for practical implementation are to have the right carer to lead and deliver the programme and the right support system in place for them (financial and supervision). Co-production also is not without challenges, the peer worker and occupational staff need to ensure that mutually valued and respected working relationship should develop. Originality/value This is the first evaluation of the impact of a carer-led psychoeducation intervention for carers of people with mental health difficulties in secondary mental health services.
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Umar, Faruk Kabir, Sule Ahmed Saidu, Sadisu Ma'aji, Muhammad Danfulani, Garba Haruna Yunusa, Ibrahim Haruna Gele, Akininibosun Raji Hafsat, Garba A. Joshua, Halimat Hassan Amin, and Yahaya Mohammed. "Baseline chest radiographic findings among HIV positive adults in a poor resource economy." Asian Journal of Medical Sciences 12, no. 7 (July 1, 2021): 52–57. http://dx.doi.org/10.3126/ajms.v12i7.33177.
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Background: Human Immunodeficiency Virus (HIV) infection has been known to pose one of the most formidable challenges to progress and development. It is a public health burden associated with high morbidity. Chest radiograph is an important tool in manifesting some of the findings associated with HIV.
Aims and Objectives: To determine the baseline chest radiographic findings among HIV positive adults in a poor resource economy.
Materials and Methods: 140 Newly diagnosed adult HIV positive, HAART naïve, participants were recruited in the Radiology Department of Usmanu Danfodiyo University Teaching Hospital (UDUTH) Sokoto and had their chest radiograph done using Silhoutte VR System GE diagnostic x-ray equipment. The processed radiographs were viewed using an illuminated viewing box and then reported by the investigator and cross-checked by another consultant Radiologist. Data collated was analysed using SPSS version 23.
Results: The study showed female to male ratio of 2.2: 1. Normal chest radiographic finding was found in 67(47.9%) participants. Pulmonary consolidation 32 (22.9%) constituted the highest abnormal chest finding. The least of the abnormal radiographic findings were emphysematous bullae 1(0.7%) and plate atelectasis 1(0.7%). Majority of the lesions were in the upper zone, 43(30.7%) and on the right side.
Conclusion: The study provides baseline data on the chest radiographic patterns among the HAART naïve HIV positive adult patients in a poor resource economy.
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Marongiu Buonaiuti, Fabrizio. "Recognition in Italy of filiation established abroad by surrogate motherhood, between transnational continuity of personal status and public policy = Il riconoscimento in Italia del rapporto di filiazione costituito all’estero tramite maternita’ surrogata, tra continuita’ dello status e ordine pubblico." CUADERNOS DE DERECHO TRANSNACIONAL 11, no. 2 (October 1, 2019): 294. http://dx.doi.org/10.20318/cdt.2019.4959.
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Abstract: A recent judgment by the Sezioni Unite of the Italian Corte di cassazione has ruled on a highly sensible and controversial issue, concerning the compatibility with the Italian public policy of a foreign court order, establishing a bond of filiation between a child born by surrogacy and the intended father, materially the same sex spouse of the biological father, despite the absence of any genetical link. The Sezioni Unite declared that such a court order could not be recognized, as incompatible with the Italian public policy. In so deciding, they appeared to have taken a step back as compared to an earlier judgment delivered by the first civil chamber of the same Corte di cassazione in 2016, where a more favourable attitude had prevailed. As compared to the said earlier judgment, the Sezioni Unite, besides distinguishing the circumstances occurring in the two cases, provided a more flexible reading of the public policy exception in private international law, partly overruling the narrower reading provided in the earlier judgment, which had limited its scope to those principles concerning the protection of fundamental rights enshrined in international and European instruments, as well as in the Italian Constitution. In the conclusions it reaches, the judgment by the Sezioni Unite reveals a substantial alignment with the solution envisaged by the European Court of Human Rights in its Advisory Opinion of 10 April 2019, contemplating adoption by the intended, non-biological parent, as the avenue by which the right of the child to his private life with that parent might be enforced.Keywords: Status filiationis, surrogate motherhood, public policy, recognition of personal and family status, Art. 8 ECHR.Riassunto: Una recente sentenza delle Sezioni Unite della Corte di cassazione ha affrontato una questione molto delicata e controversa, costituita dalla riconoscibilità in Italia di un provvedimento giurisdizionale straniero costitutivo di un rapporto di filiazione tra un minore e il padre di intenzione – materialmente il coniuge dello stesso sesso del padre biologico – in assenza di alcun legame genetico. Nell’affermare che un tale provvedimento non può essere riconosciuto in quanto in contrasto con l’ordine pubblico, le Sezioni Unite sono parse compiere un passo indietro rispetto a una precedente pronuncia della I sezione civile della stessa Cassazione del 2016, nella quale aveva prevalso un approccio di maggiore apertura. Rispetto a tale precedente pronuncia, le Sezioni Unite, oltre a sottolineare le differenze tra le fattispecie che si presentavano nei due casi, hanno adottato una definizione maggiormente flessibile del limite dell’ordine pubblico nel diritto internazionale privato, del quale la precedente decisione della sezione semplice aveva dato una lettura eccessivamente restrittiva, limitandone la portata a quei soli principi internazionalmente condivisi in materia di tutela dei diritti fondamentali e a quegli ulteriori principi che trovano affermazione nella Costituzione italiana. Nelle conclusioni raggiunte, la pronuncia delle Sezioni Unite rivela un sostanziale allineamento con la posizione assunta dalla Corte europea dei diritti dell’uomo nel suo parere consultivo del 10 aprile 2019, facendo riferimento all’adozione del minore da parte del genitore d’intenzione privo di legami biologici, come la via attraverso la quale il diritto del minore alla sua vita privata con tale genitore può ricevere tutela.Parole chiave: rapporto di filiazione, maternità surrogata, ordine pubblico, riconoscimento degli status personali e familiari, Art. 8 CEDU.
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Uddin, Ajam, Muhammad Rashedul Islam, Md Alamgir Kabir, and Md Elias Al Mamun. "A Study on Disease Patterns and Treatment Seeking Behaviors among the University Resident Students." Bangladesh Pharmaceutical Journal 23, no. 2 (July 23, 2020): 187–94. http://dx.doi.org/10.3329/bpj.v23i2.48340.
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As one of the fundamental human rights, healthcare is usually sought during illness episode. A questionnaire-based survey was conducted on 221 residential university students to identify the existing disease patterns and treatment seeking behaviors. Among the students, 22.17% were devoid of normal body-weight and 45.7% of them exercise at least three days a week. Based on smoking habits they were non-smoker (60.18%), smoker (25.34%), and second-hand smoker (14.48%). Besides, 33.03% of them have an allergy (seasonal: 24.43%; perennial: 8.60%) and 75.11% of students’ family members have or had at least one of the eight specified diseases. In 2019, around 98% of the students had suffered from at least one illness like fever-all types (86.43%), common cold (52.94%), diarrhea (20.36%), cough (46.61%), nasal congestion (10.86%), pain/aches-all types (25.79%), gastric problems (49.32%), skin diseases (15.38%), dental diseases (1.36%), eye diseases (0.9%), and many other diseases (4.52%). To mitigate these illnesses majority took medications instead of self-recovery that was highest for dental and eye diseases (100%), and lowest for cough (58.25%) and nasal congestion (58.33%). Usually, 61.99% of the residents go to Government Hospital (DMCH: 45.70%, BSMMU: 9.95%) for seeking treatment followed by University Medical Center (41.63%), Private Medical Consultant (5.88%), Private Hospital (4.52%), and others (3.62%). Moreover, 67.42% of the students take prescribed medicines as stated in prescriptions. As there is a tendency among 83.26% of the students to take medicines without prescriptions, raising awareness on the detrimental impacts of self-treatment is needed to refrain them from self-medication practices.
Bangladesh Pharmaceutical Journal 23(2): 187-194, 2020
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Naseva, Gala. "The Chasm of Structural Discrimination: Women on the Frontline Against COVID-19." Identities: Journal for Politics, Gender and Culture 17, no. 2-3 (December 30, 2020): 90–93. http://dx.doi.org/10.51151/identities.v17i2-3.458.
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The swift and unceasing spread of COVID-19 has created a new wave of complications that have revealed dozens of issues dishevelled in the gendered and obsolete state management and in the low levels of social development, primarily focusing on the Balkans. With the onset of the pandemic, women with specific diseases belong to the most critical group, given the fact that infection with COVID-19 itself increases the risk of subsequent development of numerous health complications. This text briefly highlights the negative effects of the pandemic on women from several perspectives, trying to fleetingly show its severe impact on a global level and the necessity to improve a system that is barely surviving on already unsteady grounds. Author(s): Gala Naseva Title (English): The Chasm of Structural Discrimination: Women on the Frontline Against COVID-19 Journal Reference: Identities: Journal for Politics, Gender and Culture, Vol. 17, No. 2-3 (Winter 2020) Publisher: Institute of Social Sciences and Humanities - Skopje Page Range: 90-93 Page Count: 4 Citation (English): Gala Naseva, “ The Chasm of Structural Discrimination: Women on the Frontline Against COVID-19,” Identities: Journal for Politics, Gender and Culture, Vol. 17, No. 2-3 (Winter 2020): 90-93. Author Biography Gala Naseva, Researcher Gala Naseva (1992, Skopje) is a legal researcher and interdisciplinary artist. She is currently the main editor of the multilingual Association of Young journalists from the Balkans Platform. Naseva completed her LLM in Intellectual Property Law at CEIPI, Strasbourg University and is now finishing the MA program in Gender Studies at ISSHS, North Macedonia. She was a visiting student at Justus Liebig University, Germany (Applied Theatre Studies and Musicology departments). Naseva worked as a legal consultant for the Helsinki Committee of Human Rights, USAID, The National Democratic Institute and OSCE (ODIHR). She has been engaged in the process of harmonizing various domestic legal acts with EU legislation.
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Horn, Rebecca, and Andy Keefe. "Measuring change and changing measures: The development of a torture survivor specific measure of change." Torture Journal 26, no. 2 (September 10, 2018): 22. http://dx.doi.org/10.7146/torture.v26i2.108116.
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Freedom from Torture is a UK-based human rights organisation dedicated to the treatment and rehabilitation of torture survivors. The organisation has been working towards the development of a clinical outcome tool for a number of years, and the purpose of this paper is to (a) describe the process of developing the tool and the final tool itself, and (b) to outline the system which Freedom from Torture has established to collect, record and analyse the data produced.
A review of the literature revealed that existing measures were not appropriate for measuring psychological and emotional change amongst torture survivors; therefore the organisation undertook to develop a tool specifically designed for this target group. The clinical outcome tool was developed collaboratively by Freedom from Torture clinicians, clients, interpreters and an external consultant. Initial discussions took place with clinicians and clients to develop an understanding of what psychosocial wellbeing and psychosocial distress meant to this unique population of torture survivors, and which issues and features should be included in the clinical outcome tool. A process of discussion and testing of potential approaches led to the development of a draft clinical outcome tool which was translated into 15 languages and then pilot tested with 151 clients.
The data from the pilot study was analysed and used to produce the final version of the clinical outcome tool. The clinical outcome tool was formally rolled out across the organisation’s five centres in April 2014. Clinicians working with adult clients have been completing it at the beginning of therapy and then again at regular intervals.
The data from the first year is currently being analysed, and the experiences of clinicians, clients and interpreters of using the clinical outcome tool are being reviewed, with a view to continuing to develop and improve the tool and the processes by which it is used. Ultimately, the data will be used to improve the services offered to survivors of torture in the UK.
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Kelly, Brendan D., Pat Bracken, Harry Cavendish, Niall Crumlish, Seamus MacSuibhne, Thomas Szasz, and Tim Thornton. "The Myth of Mental Illness: 50 years after publication: What does it mean today?" Irish Journal of Psychological Medicine 27, no. 1 (March 2010): 35–43. http://dx.doi.org/10.1017/s0790966700000902.
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AbstractIn 1960, Thomas Szasz published The Myth of Mental Illness, arguing that mental illness was a harmful myth without a demonstrated basis in biological pathology and with the potential to damage current conceptions of human responsibility. Szasz's arguments have provoked considerable controversy over the past five decades. This paper marks the 50th anniversary of The Myth of Mental Illness by providing commentaries on its contemporary relevance from the perspectives of a range of stakeholders, including a consultant psychiatrist, psychiatric patient, professor of philosophy and mental health, a specialist registrar in psychiatry, and a lecturer in psychiatry. This paper also includes responses by Professor Thomas Szasz.Szasz's arguments contain echoes of positivism, Cartesian dualism, and Enlightenment philosophy, and point to a genuine complexity at the heart of contemporary psychiatric taxonomy: how is ‘mental illness’ to be defined? And by whom? The basis of Szasz's doubts about the similarities between mental and physical illnesses remain apparent today, but it remains equally apparent that a failure to describe a biological basis for mental illness does not mean there is none (eg. consider the position of epilepsy, prior to the electroencephalogram). Psychiatry would probably be different today if The Myth of Mental Illness had not been written, but possibly not in the ways that Szasz might imagine: does the relentless incarceration of individuals with ‘mental illness’ in the world's prisons represent the logical culmination of Szaszian thought?In response, Professor Szasz emphasises his views that “mental illness” differs fundamentally from physical illness, and that the principal habits the term ‘mental illness’ involves are stigmatisation, deprivation of liberty (civil commitment) and deprivation of the right to trial for alleged criminal conduct (the insanity defence). He links the incarceration of the mentally ill with the policy of de-institutionalisation (which he opposes) and states that, in his view, the only limitation his work imposes on human activities are limitations on practices which are conventionally and conveniently labelled ‘psychiatric abuses’.Clearly, there remains a diversity of views about the merits of Szasz's arguments, but there is little diminution in his ability to provoke an argument.
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Luwaya, Nolundi, Kelley Moult, Diane Jefthas, and Vitima Jere. "Nick Simpson and Vivienne Mentor-Lalu." South African Crime Quarterly, no. 63 (March 30, 2018): 53–60. http://dx.doi.org/10.17159/2413-3108/2018/v0n63a4706.
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Few Capetonians would argue against the claim that the City has been rocked by the current water crisis that many have dubbed the most severe in modern history. Discussions about water saving techniques, membership of the ‘Water Warriors’ club, dinner party comparisons of family daily usage figures, discussion of toilet habits (to flush or not to flush?) and frenzied buying to secure 25-litre water containers have become part of daily life for those of us faced by the imminent (but previously unconscionable) threat of our taps running dry. Even the ‘proudly oily’1 premier of the Western Cape has boasted that she only showers every three days to help beat back Day Zero. But the water crisis has not only raised important questions about residents’ rights to, and responsibility for, the water they use. It has also brought to the surface interesting issues about criminality and crime control, and our individual and collective relationship to water. Stories of violence and incivility at water collection points and in supermarkets have captured attention on social media, and city dwellers have hotly debated the threat of organised crime, laws against rebottling and reselling of municipal water, and the Western Cape government’s Water Disaster Plan, which gives the police and army responsibility for maintaining safety and order at water collection points.
Of course, while questions of water saving, risk and safety feel quite new to many Capetonians, scholars, activists and policymakers (including criminologists) have been writing about these issues for much longer. The Centre for Law and Society approached two scholars/activists to discuss the water crisis and its impact on questions of vulnerability, risk and security. Nick Simpson, an environmental and human development consultant (and post-doctoral scholar at the University of Cape Town), discussed questions of criminology in the age of the Anthropocene, and Vivienne Mentor-Lalu, a researcher/facilitator for the Women and Democracy Initiative at the Dullah Omar Institute at the University of the Western Cape, spoke to us about the gendered impact of the drought. Nolundi Luwaya, Kelley Moult, Diane Jefthas and Vitima Jere contributed to this piece.
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Turner, Oliver, and David Leung. "On-call medical seclusion reviews: are we meeting MHA code of practice (COP) requirements?" BJPsych Open 7, S1 (June 2021): S109. http://dx.doi.org/10.1192/bjo.2021.321.
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AimsAre Junior Trainee, Medical Seclusion Reviews complaint with MHA COP Criteria?ObjectivesAre we seeing newly secluded patients on time?Are we documenting these reviews in clinical notes?Do documented reviews meet criteria stated by the MHA COP 26.133?Are we informing Higher Trainees of the need for MDT reviews?BackgroundSeclusion is an important aspect of inpatient care. MHA COP Chapter 26 provides guidance for documenting seclusion reviews, ensuring safeguards are in place to protect patient's safety and human rights. Secluded patients require a medical review within 1 hour, and four hourly thereafter, until a higher trainee or Consultant undertake an MDT Review. In our Trust, LYPFT, trainees undertake these reviews. There is noted discrepancy in seclusion review documentation. This audit identifies our compliance with time limits, and whether documentation meets the required criteria in the MHA Code of PracticeMethodOur Sample includes all Out-of-Hour Junior Trainee Medical Seclusion Reviews between 01/01/20 and 01/04/20 at LYPFT. Seclusions were identified from on call logs, and clinical notes were reviewed for a documented seclusion review. The date and time of seclusion are recorded, whether a 1 or 4 hourly review, and the time of review. We recorded any mention of: physical health; mental state; observation levels; recent medication; medication side effects; risk to others; risk to self and the need for ongoing seclusion.Result56 episodes of seclusion were identified; all 56 had a documented medical seclusion review. 49 reviews were on time, 4 were late with a documented reason, and 3 were late without. There was documentation of the Higher Trainee being informed in 53 reviews.No seclusion reviews mentioned all MHA COP criteria. We more frequently mentioned patients’ physical health (51), psychiatric health (52) and need for seclusion (54). 46 seclusion reviews mentioned risk of harm to others; only 3 mentioned risk of self-harm. 25 seclusion reviews mentioned medication, and 5 mentioned review for side effects. 5 seclusion reviews mentioned observation levels.ConclusionOur Junior Doctor Seclusion Reviews were not meeting the MHA Code of Practice Criteria, and we believe this to largely be due to lack of awareness of the standards. As such, results have been disseminated to Junior trainees in weekly teaching. We created a medical seclusion review template, adopted by the Trust, to ensure documentation compliance with the MHA COP. Junior doctor inductions now include a presentation regarding Seclusion, the reviews and documentation. We will re-audit in 12 months.
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Setiawan, Felicia, and Petrus Rudi Kasimun. "STASIUN RELAKSASI." Jurnal Sains, Teknologi, Urban, Perancangan, Arsitektur (Stupa) 3, no. 1 (May 30, 2021): 13. http://dx.doi.org/10.24912/stupa.v3i1.10837.
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Jakarta is a city that is included in the 150 most stressful cities in the world and Jakarta is in the 6th position as the most stressful city in the world. Stress has become an inherent issue in big cities and Jakarta is one of these cities. People in Indonesia, especially in Jakarta, still underestimate mental health. Because people who experience and feel stress do not have the right place to treat stress. So that the impact of untreated stress can have a negative impact on the individual and the people around. By providing a place to pay more attention to stress problems in Jakarta, it is hoped that people will no longer be taboo in consulting and treating stress problems experienced by someone. So that the relaxation station is a program that is offered to provide a healing process for people who are experiencing stress, especially in the city of Jakarta, so that people who undergo the healing process at this relaxation station are expected to achieve mental and physical relaxation and can reduce significant stress levels for their visitors. The use of the biophilic design method in this design is very important in healing to reduce stress levels in a person. Apart from using the biophilic design method, the concept of architecture and the sense is also used where this concept involves the human senses to participate in reducing stress mentally and psychologically. Keywords: Biophilic Design; Healing; Relaxation; Stress AbstrakJakarta merupakan kota yang termasuk ke dalam 150 kota paling stress di dunia dan Jakarta berada di urutan ke 6 sebagai kota paling stress di dunia. Stress sudah menjadi sebuah isu yang melekat di perkotaan besar dan jakarta salah satu kota tersebut. Masyarakat di Indonesia khususnya di Jakarta ini masih memandang kesehatan mental secara sebelah mata. Karena orang-orang yang mengalami dan merasakan stress tidak memiliki wadah yang tepat untuk mengobati rasa stress tersebut. Sehingga dampak stres yang tidak diobati dapat berdampak buruk terhadap individu maupun orang-orang disekitarnya. Dengan memberikan wadah untuk lebih memperhatikan masalah stress di Jakarta ini, diharapkan orang-orang tidak lagi tabu dalam mengkonsultasikan dan mengobati masalah stress yang di alami seseorang. Sehingga stasiun relaksasi merupakan program yang ditawarkan untuk memberikan proses healing kepada orang-orang yang mengalami stress khususnya di kota Jakarta sehingga orang yang menjalani proses healing di stasiun relaksasi ini diharapkan akan mencapai relaksasi secara pikiran dan fisik dan dapat mengurangi tingat stress yang signifikan untuk para pengunjungnya. Penggunaan metode biophilic design pada perancangan ini sangat berperan penting dalam healing untuk menurunkan tingkat stress pada seseorang. Selain menggunakan metode biophilic design di gunakan juga konsep architecture and the sense dimana konsep ini melibatkan indra dari manusia untuk ikut dalam menurunkan stress secara mental dan psikologis.
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Rahman, P., Q. Li, D. Codner, D. O’Rielly, A. Dohey, K. Jenkins, D. D. Gladman, V. Chandran, and I. Jurisica. "POS0406 miRNAs DEREGULATED IN RESPONSE TO IL17A INHIBITORS IN PSORIATIC ARTHRITIS REGULATE GENE PRODUCTS IN Rho-GTPase PATHWAYS." Annals of the Rheumatic Diseases 80, Suppl 1 (May 19, 2021): 432–33. http://dx.doi.org/10.1136/annrheumdis-2021-eular.1434.
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Background:Using transcriptomic data at initiation of therapy, we recently identified differentially expressed genes (DEGs) that separated IL-17Ai response from non-response1. Integration of cell-type-specific DEGs with protein-protein interactions (PPIs) and further comprehensive pathway enrichment analysis revealed Rho GTPase signaling pathway exhibited a strong signal specific to IL-17Ai response and particularly the genes, RAC1 and ROCKs.Objectives:To characterize microRNA (miR) profiles among IL-17Ai responders and non-responders, as it relates to RHO GTPase pathway.Methods:We interrogated 20 psoriatic arthritis (PsA) patients initiating IL-17Ai. Patients achieving at least low disease activity according to the Disease Activity Index for PsA (DAPSA) at three months were classified as responders. There were seven responders (35%) and thirteen non-responders (65%) in the IL-17Ai group, with biologic treatment naïve (bio-naïve) and previously-exposed (bio-exposed) patients exhibiting a 50% (4/8) and a 25% (3/12) response rate, respectively. For the miR analysis, CD4 positive T cells were isolated from peripheral blood mononuclear cells using DynabeadsTM CD4 beads (ThermoFisher). Total RNA was extracted from the CD4+ T cells using Lexogen’s Split RNA Extraction Kit (D-Mark Biosciences). Libraries were prepared from 200ng total RNA with the NEXTFLEX Small RNA-Seq Kit v3 with UDIs (Bioo Scientific) and sequenced on the Illumina NovaSeq 6000. Raw sequencing fastq data assessed the quality using FastQC. The miRDeep2 was used to trim the adapter, align and quantify human mature miRs from miRbase (Release 22). The abundance of miRs was converted to read counts per million, normalized and limma R package was used to identify pre- and post-differentially expressed miRs.Results:We obtained 2,889 miRs. After removing miRs with low reads in >90% of samples, 1902 high quality miRs remained for further analysis. Using mirDIP v4.1 we identified gene targets for differential miRs, and focused on recently identified DEGs related to RHO GTPase pathway. The miRs on the left of the figure 1 are those deregulated in pre-treatment, and the miRs on the right of the figure 1 show the post-treatment deregulated miRs. hsa-miR-3691-5p and hsa-miR-3161 represent the miRs that were deregulated in both conditions. The red highlighted nodes represent the most connected miRs and genes; thus, representing miRs that are the most RHO-pathway centric regulators (hsa-miR-495-3p, 16-5p, 129-5p, 520h, 520g-3p), and genes representing the most strongly regulated RHO-pathway gene products (ROCK1, RHOQ, PFN2, TAOK1, DYNC1L12, MAPRE1, PAFAH1B1, ARHGAP5, MAPK1, CALM1, DIAPH2, PKN2, ITSN1).Conclusion:Pre- and post-treatment differential miRs related to IL-17Ai response regulate multiple genes from RHO GTPase pathway.References:[1]Rahmati S, O’Rielly DD, Li Q, Codner D, Dohey A, Jenkins K, Jurisica I, Gladman DD, Chandran V, Rahman P. Rho-GTPase pathways may differentiate treatment response to TNF-alpha and IL-17A inhibitors in psoriatic arthritis. Sci Rep. 2020 Dec 10;10(1):21703.Figure 1.Disclosure of Interests:Proton Rahman Speakers bureau: AbbVie, Amgen, BMS, Celgene, Eli Lily, Janssen, Merck, Novartis, Pfizer, UCB, Consultant of: AbbVie, Amgen, BMS, Celgene, Eli Lily, Janssen, Merck, Novartis, Pfizer, UCB, Grant/research support from: Janssen, Novartis, Quan Li: None declared, Dianne Codner: None declared, Darren O’Rielly: None declared, Amanda Dohey: None declared, Kari Jenkins: None declared, Dafna D Gladman Speakers bureau: AbbVie, Amgen, BMS, Eli Lily, Galapagos, Gilead, Janssen, Novartis, Pfizer, UCB, Consultant of: AbbVie, Amgen, BMS, Eli Lily, Galapagos, Gilead, Janssen, Novartis, Pfizer, UCB, Grant/research support from: AbbVie, Amgen, Eli Lily, Janssen, Novartis, Pfizer, UCB, Vinod Chandran Speakers bureau: AbbVie, Amgen, BMS, Eli Lily, Janssen, Novartis, Pfizer, UCB, Paid instructor for: AbbVie, Amgen, BMS, Eli Lily, Janssen, Novartis, Pfizer, UCB, Grant/research support from: AbbVie, Amgen, Eli Lily, Employee of: Spousal Employment Eli Lilly, Igor Jurisica: None declared
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Terenko, Olena. "CONCEPTUAL IDEAS AND ORIENTATORS OF THE NOTHERN AMERICAN MODEL OF ADULT EDUCATION." EUREKA: Social and Humanities 3 (May 31, 2019): 38–43. http://dx.doi.org/10.21303/2504-5571.2019.00906.
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The article deals with conceptual ideas and orientators of Northern American model of adult education. It is substantiated, that Nothern American model of adult education is based on the following philosophical directions: liberalism, progressivism, behaviorism, humanism, radicalism, constructivism. Liberalism has ancient roots and comes from the fact that since man is the real source of progress in society, it is necessary to ensure his rights and freedoms, providing equal access to education regardless of social status and well-being. The basic principle of liberal education is singled out, in particular, to develop a personality that is consonant with the purpose of a liberal education in ancient times - the education of citizens who can become active participants in a democratic society. It is proved that non-formal adult education should be continuous, focus on the development of intellectual abilities, be accessible to all sections of the population, and its content must meet their needs. It was found out that the historical roots of the philosophy of progressivism associated with progressive political movement in society and education. Its basis is the concept of interaction between education and society, empirical theory of education democratization of education. It was found out that behavioral direction, whose founder was John Watson, appeared in the USA in the early XX century. Based on the theory of Pavlov's conditioned reflexes, his supporters (J. Watson, B. Sninner E. Thorndike) examined personality as a set of behavioral responses to stimuli of the environment. It is identified that the purpose of adult education - behavior modification adult-oriented changes in humans. It was proved, that unlike behaviorists, representatives of humanistic direction (J. Brown, Johnson, Maslow, M. Knowles, K. Rogers, etc.) considered man independent, active, open to change and self-actualization person. It was stressed, that the founders of the radical trend, based on theories of anarchism, marxism, socialism, considering education in general and adult education, in particular, as an important mechanism to achieve radical changes in society. It updates the social role of non-formal adult education, because it requires critical thinking and personal participation in these changes. It was found out, that according to philosophy of constructivism person is unique in his/her vision of the world, beliefs, outlook because he/she is able to construct his/her personal understanding of reality. A teacher is not just a transmitter of knowledge,he/she serves as the consultant, moderator, facilitator. The analysis of scientific literature showed that adult education in the USA has evolved with the development of society, and has a long history and some traditions, mainly seen as informal adult education, aimed at self-improvement of adult to meet his/her educational needs; mechanism of civil society formation.
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Čiužas, Renaldas. "The Importance of Teacher Competencies to the Formation of Students National Identity." Pedagogika 109, no. 1 (March 26, 2013): 27–32. http://dx.doi.org/10.15823/p.2013.1830.
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Over the past few years the education community in Lithuania often discusses the issues concerning the education and formation of national identity of younger generation. Interest in this topic is based on facts that emigration of younger generation in Lithuania is not decreasing, that school-age children and youth feel lack of ethnic self-consciousness and national identity. Assumption that teachers play the important role in the formation of national identity for children and young people isn’t excluded.
Personal identity as self sensation begins to form in early childhood. In this process the important role performs first of all parents, then other family members and later the school.
National identity are formed continuously. The societies openness to other cultures, increase of individuals and nations international relations, lifestyle influenced by globalization, wish to learn about other cultures raise new requirements for education process in schools where national identity has important role in the teaching paradigm [2]. It is expected that schools provide not only knowledge and skills necessary for life in knowledge society, but also develop students‘ tolerance for other cultures and help them become aware of the meaning of his national cultural.
As observed by L. Duoblienė (2009), educational theorists during discussions how to change the educational process under the new circumstances proposes first of all to strengthen students media literacy as well as intercultural education that teach younger generation to resist the influence of ideologies and unconscious misrepresentations, change youth provisions. The teacher’s role in this process becomes significant.
The purpose of this article is to reveal the importance of teacher competence to the formation of students national identity.
The object of this article – teacher competence.
The scientific literature analysis was used in this article.
The article consists of two parts: the first part analyses the complexity of the concept of teacher competence, and the second part analyses the teacher competence Framework and it’s importance to the formation of students national identity. After reviewing of scientific literature the following conclusions are formulated:
The teacher in modern school play in their daily activities not only the role of traditional teacher by giving new knowledge for students. Today teacher is a consultant, an advisor, elder friend, a researcher and so on. It is difficult to list all roles of today teacher. But teachers‘ knowledge, skills, personal qualities and values affects not only students learning motivation and achievement, but also formation of their national identity.
Teacher competencies can be categorized into the three groups: general competencies, professional competencies and special competencies. The competency framework allow for teacher to become professional in particular teaching subject or sphere, enables him to organize the educational process and feel comfortable in a professional environment.
To help the teacher to know and be able to help students to form their national identity is very important teachers‘ common-cultural competence. The teacher need to be characterized by ethnic, racial and religious tolerance, to have knowledge about civil liberties, human rights and obligations, and be able to ensure it within its capabilities.
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Laborie, Francois. "Guest Editorial: Data Are the Sustainable Secret to a More Profitable Future." Journal of Petroleum Technology 73, no. 03 (March 1, 2021): 10–11. http://dx.doi.org/10.2118/0321-0010-jpt.
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I was recently asked if I thought that the oil and gas industry would bounce back once the world is rid of the coronavirus. It was a question prompted by the sharp decline in activity in several oil-and-gas-dependent sectors such as transportation. The coronavirus and its subsequent impact on the price of oil have injected a sense of uncertainty into the industry, prompting many to speculate as to what will happen once the pandemic abates. Rather than asking if we’ll bounce back, I’d prefer we focus on how fast we can learn from the challenges and move forward. The oil and gas industry has come to a point at which there is no turning back. The pressure to transform was mounting long before COVID-19 entered our vocabulary. Recent events only highlight the urgency of it. It is an urgency that stems from new regulation, increasing financial pressure, and growing societal expectations. From the Paris Agreement to the UN’s Sustainable Development Goals, the world has come to terms with the fact that our planet is not immune to human impact and that we need to take measures to mitigate our damage to it. For oil and gas, that means transformation, in both the short and long term, all the while remaining profitable and competitive. In the shorter term, the world is not able to fill the void that going completely fossil-free would create. Oil and gas are still key components of the global energy system, driving both social and economic development in much of the world. That means that while our dependency remains, the extraction of this natural resource and its subsequent processing need to be done as safely, efficiently, and as carbon-friendly as possible. That’s where technology stands to play a pivotal role. For oil and gas operations, achieving near-term, sustainable success will require three things. Optimizing the use of data for increased transparency. There are savings to be had across oil and gas operations. In 2017, global management consultant McKinsey & Company reported that the industry’s performance gap was around $200 billion and that most offshore platforms are only running at 77% of their maximum potential. This means that there is significant ground to be gained. Today, we have the tools available to capture this value, to extract the data, and identify where there is waste and where there is opportunity. This kind of accountability is possible only if you are transparent with your data, which requires the right tools to uncover it, understand it, and share it. Several oil and gas players today have already cracked the code to learn how to use data to ensure more sustainable operations. By gaining an understanding of the inherent power of data flowing through their operations and by embracing transparency around that data, they can harness it to their advantage. Norway-based oil and gas operator Aker BP is one such example. Working with Cognite, it recently implemented machine learning to improve water- contamination detection, saving $6 million per year and reducing the company’s environmental impact. The massive savings for both the companies and the environment was achieved with the smarter and more open use of data.
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Usmani, Saad Z., Maria-Victoria Mateos, Hareth Nahi, Sebastian Grosicki, Vladimir I. Vorobyev, Ivan Spicka, Vania T. M. Hungria, et al. "Randomized, Open-Label, Non-Inferiority, Phase 3 Study of Subcutaneous (SC) Versus Intravenous (IV) Daratumumab (DARA) Administration in Patients with Relapsed or Refractory Multiple Myeloma: Columba Update." Blood 134, Supplement_1 (November 13, 2019): 1865. http://dx.doi.org/10.1182/blood-2019-122765.
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INTRODUCTION: Daratumumab (DARA), a human IgGκ monoclonal antibody targeting CD38, is approved for intravenous (IV; 16 mg/kg) administration as a single agent or in combination with standard-of-care regimens for treatment of multiple myeloma (MM).To improve safety and reduce patient and healthcare provider burden, a subcutaneous (SC) formulation of DARA (1,800 mg co-formulated with recombinant human hyaluronidase PH20 [rHuPH20]; ENHANZE® drug delivery technology, Halozyme, Inc.) was developed. The phase 3, randomized, open-label, non-inferiority COLUMBA study (NCT03277105) evaluated the efficacy, PK, and safety of DARA SC vs DARA IV in patients (pts) with RRMM. The results, showing the study met both co-primary endpoints (overall response rate [ORR] and Ctrough) at a median follow-up of 7.5 months, were previously presented. Here, we present updated data with longer follow-up. METHODS: DARA SC (1,800 mg DARA + rHuPH20 [2,000 U/mL]) and DARA IV (16 mg/kg IV infusion) were given in 28-day cycles: QW Cycles 1-2, Q2W Cycles 3-6, and Q4W thereafter. DARA SC (15 mL) was given by manual push over 3-5 mins at alternating left/right abdominal sites. Eligible pts (≥18 yrs) with RRMM had ≥3 prior lines of therapy (LOT), including a PI and an IMiD, or were double refractory. Co-primary endpoints were overall response rate (ORR; analyzed by Farrington-Manning test, with non-inferiority defined as 60% retention of ORR) and maximum DARA Ctrough (pre-dose concentration on Cycle 3 Day 1; non-inferiority defined as the lower bound of 90% confidence interval [CI] for the ratio of the geometric means [GM] ≥80%). Secondary endpoints included rates of infusion-related reactions (IRRs), progression-free survival (PFS), very good partial response or better (≥VGPR), and complete response or better (≥CR). RESULTS: A total of 522 pts were randomized to receive DARA SC (n = 263) or DARA IV (n = 259). Median age was 67 yrs (20% ≥75 yrs). Median baseline body weight was 73 kg. Pts received a median of 4 LOT and 100% of pts were previously treated with both PI(s) and IMiD(s). 82.2% of pts were refractory to the last line of prior therapy, and 49.4% were refractory to both PI and IMiDs. 26.3% and 17.3% of pts had a high-risk cytogenetic abnormality at baseline in the DARA SC and DARA IV groups, respectively. After a median follow-up of 13.8 months, ORR was improved from 41.1% to 43.7% for DARA SC and 37.1% to 39.4% for DARA IV (Figure). ORR were comparable across all subgroups, including body weight. Rates of deep responses (≥VGPR, ≥CR) were similar between DARA SC and DARA IV, and deeper with longer follow-up (Figure). Median duration of treatment (~5.5 months) was similar for DARA SC and DARA IV. A significantly lower rate of IRRs was observed with DARA SC vs DARA IV. At the time of data cutoff, 118 pts (evenly distributed across both arms) continued treatment on study. CONCLUSIONS: With longer follow-up, safety and efficacy data continue to support that DARA SC and DARA IV have similar safety profiles with a statistically significant reduction in IRR rates. DARA SC has a reduced treatment burden due to a considerably shorter administration duration, and DARA SC pts reported higher treatment satisfaction. Collectively, the data demonstrate a favorable benefit/risk profile for the use of an 1800 mg flat dose of DARA SC. Disclosures Usmani: Amgen, Celgene, Janssen, Sanofi, Takeda: Speakers Bureau; Amgen, Bristol-Myers Squibb, Celgene, Janssen, Merck, SkylineDX, Takeda: Other: Consultant/Advisor; Amgen Array Biopharma, Bristol-Myers Squibb, Celgene, Janssen, Merck, Pharmacyclics, Sanofi, Takeda: Other: Research Grant. Mateos:Amgen Inc, Janssen Biotech Inc: Other: Data and Monitoring Committee; Janssen, Celgene, Takeda, Amgen, Adaptive: Honoraria; AbbVie Inc, Amgen Inc, Celgene Corporation, Genentech, GlaxoSmithKline, Janssen Biotech Inc, Mundipharma EDO, PharmaMar, Roche Laboratories Inc, Takeda Oncology: Other: Advisory Committee; Amgen Inc, Celgene Corporation, Janssen Biotech Inc, Takeda Oncology.: Speakers Bureau; Janssen, Celgene, Takeda, Amgen, GSK, Abbvie, EDO, Pharmar: Membership on an entity's Board of Directors or advisory committees. Vorobyev:Abbvie: Consultancy, Speakers Bureau; Janssen: Consultancy, Speakers Bureau; Roche: Consultancy, Speakers Bureau; AstraZeneca: Consultancy; Takeda: Consultancy, Speakers Bureau; Sanofi: Consultancy. Spicka:Sanofi: Consultancy; Janssen-Cilag: Consultancy, Honoraria; Takeda: Consultancy, Honoraria; Amgen: Consultancy, Honoraria; Novartis: Consultancy, Honoraria; Sanofi: Consultancy; Janssen-Cilag: Consultancy, Honoraria; Takeda: Consultancy, Honoraria; Celgene: Consultancy, Honoraria; Amgen: Consultancy, Honoraria; Novartis: Consultancy, Honoraria; Celgene: Consultancy, Honoraria. Hungria:Takeda: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Takeda: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Amgen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Amgen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; BMS: Consultancy, Honoraria, Speakers Bureau; BMS: Consultancy, Honoraria, Speakers Bureau; Janssen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Abbvie: Consultancy, Membership on an entity's Board of Directors or advisory committees; Abbvie: Consultancy, Membership on an entity's Board of Directors or advisory committees; Celgene: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Janssen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Celgene: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau. Bladé:Irctures: Honoraria; Janssen, Celgene, Amgen, Takeda: Membership on an entity's Board of Directors or advisory committees. Moreau:Amgen: Consultancy, Honoraria; Celgene: Consultancy, Honoraria; Janssen: Consultancy, Honoraria; AbbVie: Consultancy, Honoraria; Takeda: Consultancy, Honoraria. Kaiser:Abbvie, Celgene, Takeda, Janssen, Amgen, Abbvie, Karyopharm: Consultancy; Celgene, Janssen: Research Funding; Takeda, Janssen, Celgene, Amgen: Honoraria, Other: Travel Expenses. Iida:Takeda: Honoraria, Research Funding; Celgene: Honoraria, Research Funding; Gilead: Research Funding; Sanofi: Research Funding; MSD: Research Funding; Abbvie: Research Funding; Kyowa Kirin: Research Funding; Chugai: Research Funding; Novartis: Honoraria, Research Funding; Bristol-Myers Squibb: Honoraria, Research Funding; Janssen: Honoraria, Research Funding; Teijin Pharma: Research Funding; Daichi Sankyo: Honoraria, Research Funding; Astellas: Research Funding. Masterson:Janssen: Employment, Equity Ownership. Lantz:Janssen: Employment, Equity Ownership. O'Rourke:Janssen: Employment, Equity Ownership. Heuck:Janssen: Employment. Qin:Janssen: Employment, Equity Ownership. Parasrampuria:Janssen: Employment, Equity Ownership. Qi:Janssen: Employment. Bahlis:Amgen: Consultancy, Honoraria; Takeda: Consultancy, Honoraria; AbbVie: Consultancy, Honoraria; Janssen: Consultancy, Honoraria; Celgene: Consultancy, Honoraria. OffLabel Disclosure: This presentation/paper includes information/discussion of a subcutaneous formulation of daratumumab, which is currently under investigation in several clinical trials, but has not yet been approved. The intravenous formulation of daratumumab is approved as monotherapy and in combination with standard-of-care regimens for the treatment of MM.
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Mateos, Maria-Victoria, Saad Z. Usmani, Sebastian Grosicki, Vladimir I. Vorobyev, Ivan Spicka, Vania T. M. Hungria, Sibirina Korenkova, et al. "Randomized, Open-Label, Non-Inferiority, Phase 3 Study of Subcutaneous (SC) Versus Intravenous (IV) Daratumumab (DARA) Administration in Patients (Pts) with Relapsed or Refractory Multiple Myeloma (RRMM): Body Weight Subgroup Analysis of Columba." Blood 134, Supplement_1 (November 13, 2019): 1906. http://dx.doi.org/10.1182/blood-2019-122501.
Full textAbstract:
Introduction: DARA, a human CD38 monoclonal antibody (mAb), is approved for intravenous (IV; 16 mg/kg) administration as a single agent or in combination with standard-of-care regimens for treatment of multiple myeloma. To reduce patient and provider burden and improve safety, a subcutaneous (SC) co-formulation of DARA (flat dose of 1,800 mg, ~70% bioavailability) with recombinant human hyaluronidase PH20 (rHuPH20; ENHANZE® drug delivery technology, Halozyme, Inc.) was developed. The phase 3, randomized, open-label COLUMBA study (NCT03277105) demonstrated the non-inferiority of DARA SC vs DARA IV in terms of co-primary endpoints (ORR and Ctrough) in pts with RRMM at a median of 7.5 months follow-up. Here, we present a body weight subgroup analysis of COLUMBA, based on data from the primary analysis. Methods: DARA SC (flat dose of 1,800 mg DARA + rHuPH20 [2,000 U/mL]) and DARA IV (16 mg/kg) were given in 28-day cycles: QW Cycles 1-2, Q2W Cycles 3-6, and Q4W thereafter. DARA SC (15 mL) was given by manual push over 3-5 mins at alternating left/right abdominal sites. Eligible pts (≥18 yrs) with RRMM had ≥3 prior lines of therapy, including a PI and an IMiD, or were double refractory. Co-primary endpoints were overall response rate (ORR) and maximum DARA Ctrough (pre-dose concentration on Cycle 3 Day 1 [C3D1]). A subgroup analysis was performed by body weight (≤65 kg, >65 to 85 kg, and >85 kg). Results: In the intent-to-treat (ITT) population, 522 pts were randomized to receive DARA SC (n = 263) or DARA IV (n = 259). Median baseline body weight was 73 kg. Flat dose DARA SC achieved adequate exposure for all body weight subgroups, as maximum Ctrough (C3D1 predose) exceeded the 236 μg/mL threshold previously established in DARA IV studies as necessary for 99% target saturation (Xu XS, et al. Clin Pharmacol Ther, 2017). Across each subgroup, there was considerable overlap in maximum Ctrough for both treatment groups (Figure); however, mean DARA concentrations were 60% higher for pts ≤65 kg and 12% lower for pts >85 kg treated with DARA SC vs IV. Nevertheless, the range of Ctrough across body weights for DARA SC was within the previously observed range (36 to 1764 µg/mL for C3D1 Ctrough) for the approved DARA IV 16 mg/kg. ORR in the ITT population was 41.1% vs 37.1% for DARA SC vs DARA IV. In the body weight subgroups, ORR was 43.6% vs 38.0%, 37.3% vs 39.0%, and 43.9% vs 32.8% for DARA SC vs IV in the ≤65 kg, >65 to 85 kg, and >85 kg groups, respectively. These data suggest that the slightly lower exposure observed at higher body weights was not clinically relevant. For both treatment groups, the incidence of grade 3/4 TEAEs, grade 5 TEAEs, serious TEAEs, and IRRs was similar across body weight subgroups. An increased incidence of TEAEs of any grade with decreasing body weight for DARA SC (≤65 kg, 94.6%; >65 to 85 kg, 87.3%; >85 kg, 78.5%) was observed; incidence of any grade TEAEs was similar across body weight subgroups for DARA IV (≤65 kg, 89.1%; >65 to 85 kg, 89.5%; >85 kg, 88.5%). At the preferred term level, an decreased incidence of grade 3/4 thrombocytopenia (≤65 kg, 16.1%; >65 to 85 kg, 14.7%; >85 kg, 9.2%) and grade 3/4 neutropenia (≤65 kg, 20.4%; >65 to 85 kg, 9.8%; >85 kg, 7.7%) with increasing body weight was observed for DARA SC. An increased incidence of grade 3/4 hypertension (≤65 kg, 4.3%; >65 to 85 kg, 5.7%; >85 kg, 9.8%) with increasing body weight was observed for DARA IV. However, the incidence of maximum Grade 3 and 4 TEAEs (DARA SC, 43.0%; DARA IV, 44.6%) and the incidence of Grade 5 TEAEs (6.5% for both) were similar between treatment groups in the lowest body weight subgroup. For subjects ≤65 kg, DARA SC had a lower incidence of serious TEAEs (DARA SC, 23.7%; DARA IV, 30.4%). Conclusions: In the primary analysis, efficacy and PK co-primary endpoints were met, demonstrating non-inferiority of DARA SC to DARA IV, with similar safety profiles and significant reduction in IRR rates with DARA SC. In this subgroup analysis, ORR in all body weight subgroups was consistent with ORR in the overall population. DARA SC achieved adequate exposure and was well tolerated across all body weight subgroups. The higher concentration of DARA SC in pts ≤65 kg did not have a clinically relevant effect on safety, suggesting no dose individualization is necessary on the basis of weight. Disclosures Mateos: Amgen Inc, Celgene Corporation, Janssen Biotech Inc, Takeda Oncology.: Speakers Bureau; AbbVie Inc, Amgen Inc, Celgene Corporation, Genentech, GlaxoSmithKline, Janssen Biotech Inc, Mundipharma EDO, PharmaMar, Roche Laboratories Inc, Takeda Oncology: Other: Advisory Committee; Janssen, Celgene, Takeda, Amgen, Adaptive: Honoraria; Janssen, Celgene, Takeda, Amgen, GSK, Abbvie, EDO, Pharmar: Membership on an entity's Board of Directors or advisory committees; Amgen Inc, Janssen Biotech Inc: Other: Data and Monitoring Committee. Usmani:Amgen, Bristol-Myers Squibb, Celgene, Janssen, Merck, SkylineDX, Takeda: Other: Consultant/Advisor; Amgen, Celgene, Janssen, Sanofi, Takeda: Speakers Bureau; Amgen Array Biopharma, Bristol-Myers Squibb, Celgene, Janssen, Merck, Pharmacyclics, Sanofi, Takeda: Other: Research Grant. Vorobyev:Abbvie: Consultancy, Speakers Bureau; Takeda: Consultancy, Speakers Bureau; AstraZeneca: Consultancy; Janssen: Consultancy, Speakers Bureau; Roche: Consultancy, Speakers Bureau; Sanofi: Consultancy. Spicka:Amgen: Consultancy, Honoraria; Celgene: Consultancy, Honoraria; Celgene: Consultancy, Honoraria; Janssen-Cilag: Consultancy, Honoraria; Takeda: Consultancy, Honoraria; Novartis: Consultancy, Honoraria; Takeda: Consultancy, Honoraria; Sanofi: Consultancy; Novartis: Consultancy, Honoraria; Sanofi: Consultancy; Janssen-Cilag: Consultancy, Honoraria; Amgen: Consultancy, Honoraria. Hungria:Amgen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; BMS: Consultancy, Honoraria, Speakers Bureau; BMS: Consultancy, Honoraria, Speakers Bureau; Janssen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Abbvie: Consultancy, Membership on an entity's Board of Directors or advisory committees; Abbvie: Consultancy, Membership on an entity's Board of Directors or advisory committees; Amgen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Celgene: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Takeda: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Takeda: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Celgene: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau; Janssen: Consultancy, Honoraria, Membership on an entity's Board of Directors or advisory committees, Speakers Bureau. Bahlis:Celgene: Consultancy, Honoraria; Amgen: Consultancy, Honoraria; Janssen: Consultancy, Honoraria; Takeda: Consultancy, Honoraria; AbbVie: Consultancy, Honoraria. Bladé:Janssen, Celgene, Amgen, Takeda: Membership on an entity's Board of Directors or advisory committees; Irctures: Honoraria. Moreau:Janssen: Consultancy, Honoraria; Amgen: Consultancy, Honoraria; Takeda: Consultancy, Honoraria; AbbVie: Consultancy, Honoraria; Celgene: Consultancy, Honoraria. Kaiser:Celgene, Janssen: Research Funding; Abbvie, Celgene, Takeda, Janssen, Amgen, Abbvie, Karyopharm: Consultancy; Takeda, Janssen, Celgene, Amgen: Honoraria, Other: Travel Expenses. Iida:Abbvie: Research Funding; Kyowa Kirin: Research Funding; Chugai: Research Funding; Novartis: Honoraria, Research Funding; Gilead: Research Funding; Astellas: Research Funding; Teijin Pharma: Research Funding; Celgene: Honoraria, Research Funding; Janssen: Honoraria, Research Funding; MSD: Research Funding; Sanofi: Research Funding; Bristol-Myers Squibb: Honoraria, Research Funding; Daichi Sankyo: Honoraria, Research Funding; Takeda: Honoraria, Research Funding. Masterson:Janssen: Employment, Equity Ownership. Lantz:Janssen: Employment, Equity Ownership. O'Rourke:Janssen: Employment, Equity Ownership. Qin:Janssen: Employment, Equity Ownership. Parasrampuria:Janssen: Employment, Equity Ownership. Heuck:Janssen: Employment. Qi:Janssen: Employment. OffLabel Disclosure: This presentation/paper includes information/discussion of a subcutaneous formulation of daratumumab, which is currently under investigation in several clinical trials, but has not yet been approved. The intravenous formulation of daratumumab is approved as monotherapy and in combination with standard-of-care regimens for the treatment of MM.
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"LEGAL AND INSTITUTIONAL FRAMEWORK IN THE FIELD OF USE OF INFORMATION AT THE INTERNATIONAL REGIONAL LEVEL." Journal of V. N. Karazin Kharkiv National University, Series "Law", no. 29 (2020). http://dx.doi.org/10.26565/2075-1834-2020-29-48.
Full textAbstract:
The article analyzes international legal acts (American Convention on Human Rights, Inter-American Model Law on Access to Public Information, Model Law on Access to Information for Africa, Convention for the Protection of Human Rights and Fundamental Freedoms, Declaration on Freedom of Expression and Information, Convention for the Protection of Individuals with regard to Automatic Processing of Personal Data, Recommendations of the Committee of Ministers of the Council of Europe, Model Law on Informatization, Information and Information Protection, Model Inform Codes for the CIS member states, etc.) adopted within the framework of international intergovernmental organizations (Organization of American States, African Union, Council of Europe, Commonwealth of Independent States, etc.) at the regional level regarding the right to information. It is stated that this right includes freedom to hold opinions without interference and to seek, receive and impart information and ideas through any media. Attention is paid to the issue of access to public information that is in the use, possession or control of any government agency, including the types of information to be published (organizational structure, functions, responsibilities, procurement procedures, complaint mechanisms, etc.); the article analyzes the procedure for responding to requests for access to public information by public authorities. Attention is drawn to the respect for the right to information in the aspect of use of information and communication technologies. Attention is paid to the activities of specially authorized persons, monitoring institutions, bodies for compliance with international agreements in the field of information (Office of the Special Rapporteur on Freedom of Expression, Special Rapporteur on Freedom of Expression and Access to Information, Advisory Committee, The Council of Europe Data Protection Commissioner etc.). It is indicated that these bodies and officials established at the international regional level perform a number of functions, including: general monitoring of freedom of expression and access to information standards, investigation of specific situations of systemic violations of the right to freedom of expression and denial of access to information, cooperation with national authorities and human rights institutions, consulting Member States etc. The relevant conclusions have been drawn.
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Williams, Brett. "Removal of Invasive Devices from Deceased Persons: Forensic implications for Paramedics – a Victorian perspective." Australasian Journal of Paramedicine 3, no. 4 (July 14, 2015). http://dx.doi.org/10.33151/ajp.3.4.339.
Full textAbstract:
Professor Cordner is Professor of forensic medicine at Monash University Institutes of Health and Director of the Victorian Institute of Forensic Medicine His work in the area of forensic medicine and human rights has seen him take tours of duty in East Timor and Kosovo, as well as a year-long stint consulting to the International Committee of the Red Cross in Geneva. The following interview was conducted to invite Professor Cordner’s professional opinion in relation to practices and implications with respect to the removal of invasive clinical devices from deceased persons, as they currently apply to paramedics of Metropolitan Ambulance Service in Melbourne, and Rural Ambulance Victoria.
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"Legal Aspects of Formation of Information Jurisdiction of Future Jurists: The Practice of Creating a Web Portfolio." Journal of V. N. Karazin Kharkiv National University, Series "Law", no. 28 (2019). http://dx.doi.org/10.26565/2075-1834-2019-28-13.
Full textAbstract:
The article states that total and radical changes are taking place in society in all spheres, and legislative provision of the sphere of providing educational services in the field of higher legal education is gradually emerging; noted that the conceptual vision of the problem as a whole has not yet emerged; it is stated that human rights are on the surface of all social transformations, and the right among others belongs to the right to information, therefore the aspect of implementation and protection of personal data on the Internet, scientific substantiation, legal regulation of these rights and consolidation of their respective status are relevant; it was also noted that in the conditions of post-industrial society the issues of informatization of the Ukrainian educational space are very topical; it is a question that their decision should be made not only by dynamic methods of development of information educational environment, but also by search of new means, forms and ways of interaction of socio-cultural institutions (media and education), as well as support and evaluation of the effectiveness of the educational process in the conditions of information society; noted that today these tasks are intended to be solved by media education; formation of media competence directly concerns future jurists, since they are responsible for the transfer of knowledge and experience in practice, that is, consulting activities in the context of universal informatization; the issue of media competence of the future jurist is also being updated because the society is experiencing a discrepancy in the experience of interaction with the media in the older generation and young people; it is noted that, because of media creation, a teacher in higher education institution will be able to expand the students' view of future jurisprudence, about the media, to reveal the intellectual potential of modern information technologies and "media culture as a means for further continuous self-education"; it was stated that for a long time the portfolio was used only as an authentic evaluation of the results of the students' educational and professional achievements, but its possibilities are obviously much wider; "Web Portfolio" is a web-based resource that reflects the growth of the owner's educational or professional achievements; the value of such a web-portfolio is also evident in the issue of potential employment and in the self-presentation of oneself as a competent specialist, ready to live and work in the conditions of the information society; it was noted that the web portfolio should be put into operation of the institutions of higher education; indicated that there are also so-called "false portfolios", representing a specialist with no work experience, but with the available skills; stated that the issue of creating a web-portfolio is relevant for the higher education of future jurists; also noted that there is a danger of being "hostage" to the network and, in general, it is difficult to resist, counter, prevent and combat threatening challenges on the network.
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Mayer, Claude-Hélène, Rian Viviers, and Louise Tonelli. "‘The fact that she just looked at me…’ – Narrations on shame in South African workplaces." SA Journal of Industrial Psychology 43 (January 23, 2017). http://dx.doi.org/10.4102/sajip.v43i0.1385.
Full textAbstract:
Orientation: Shame has been internationally researched in various cultural and societal contexts as well as across cultures in the workplace, schools and institutions of higher education. It is an emotional signal that refers to experienced incongruence of identity goals and the judgement of others.Research purpose: The purpose of this study was to focus on experiences of shame in the South African (SA) workplace, to provide emic, in-depth insights into the experiences of shame of employees.Motivation for the study: Shame in the workplace often occurs and might impact negatively on mental health and well-being, capability, freedom and human rights. This article aims at gaining some in-depth understanding of shame experiences in SA workplaces. Building on this understanding the aim is to develop awareness in Industrial and Organisational Psychologists (IOPs), employees and organisations to cope with shame constructively in addition to add to the apparent void in the body of knowledge on shame in SA workplaces.Research design, approach and method: An interpretative hermeneutical research paradigm, based on Dilthey’s modern hermeneutics was applied. Data were collected through semistructured interviews of 11 employees narrating their experiences from various workplaces, including the military, consulting organisations and higher education institutions. Content analysis was used for data analysis and interpretation.Main findings: The major themes around which shameful experiences evolved included loss of face, mistreatment by others, low work quality, exclusion, lifestyle and internalised shame on failure in the workplace. Shame is experienced as a disturbing emotion that impacts negatively on the self within the work context. It is also experienced as reducing mental health and well-being at work.Practical/managerial implications: SA organisations need to be more aware of shame in the workplace, to address the potential negative effects of shame on employees, particularly if they are not prepared to reframe shame into a constructively and positively used emotion. Safe spaces should be made available to talk about shame. Strategies should be applied to deal with shame constructively.Contribution/value-add: This article expands an in-depth understanding of shame from emic and culture-specific perspectives within SA workplaces. The findings are beneficial to IOPs and organisations to understand what shame is from the perspective of SA employees across cultural groups. The article thereby adds value to theory and practice, offering IOPs a deeper understanding of shame in the work context.
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Nivedhitha, G., E. Punarselvam, K. R. Aaghash, M. Elayabarathi, K. Rahul, and R. Santhosh. "Ai Consulting Healthcare Chatbot System Using Pattern Matching." International Journal of Scientific Research in Science and Technology, January 5, 2021, 18–22. http://dx.doi.org/10.32628/ijsrst2182112.
Full textAbstract:
In today's world there are millions of diseases with various symptoms foreach, no human can possibly know about all of these diseases and the treatmentsassociated with them. So, the problem is that there isn’t any place where anyone can have the details of the diseases or the medicines/treatments. What if there is a placewhere you can find your health problem just by entering symptoms or the currentcondition of the person. It will help us to deduce the problem and to verify thesolution. The proposed idea is to create a system with artificial intelligence that canmeet these requirements. The AI can classify the diseases based on the symptomsand give the list of available treatments. The System is a text-to-text diagnosis chatbot that will engage patients in conversation with their medical issues and provides apersonalized diagnosis based on their symptoms and profile. Hence the people canhave an idea about their health and can take the right action.
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"Palestinian Strategic Options: An Attempt at Analysis to Inform Action." Journal of Palestine Studies 35, no. 1 (January 1, 2005): 91–102. http://dx.doi.org/10.1525/jps.2005.35.1.91.
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In March 2005, a group of independent intellectuals and community leaders engaged in a roundtable discussion of the current challenges facing the Palestinian people and possible strategies for realizing Palestinian rights. This report presents a synthesis of the discussions; the views expressed do not necessarily represent a consensus. Roundtable participants included Naseer Aruri, chancellor professor (emeritus) of political science, University of Massachusetts Dartmouth; Sami AlBanna, director of strategy and systems architecture, consultant; Phyllis Bennis, fellow, New Internationalism Project, Institute for Policy Studies; George Bisharat, professor of law, Hastings College, University of California; Jamil Dakwar, international human rights advocate; Bill Fletcher, Jr., president, TransAfrica Forum; Linah Habbab AlBanna, psychologist; Nadia Hijab, senior fellow, Institute for Palestine Studies (report editor); and David Wildman, executive officer, Human Rights Office, General Board of Global Ministries, United Methodist Church.