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Relevant bibliographies by topics / Human proteases

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Dissertations / Theses

Academic literature on the topic 'Human proteases'

Author: Grafiati

Published: 14 March 2023

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Dissertations / Theses on the topic "Human proteases"

1

Lourbakos, Afrodite 1972. "Activation of human protease-activated receptors by proteases from a periodontal pathogen." Monash University, Dept. of Biochemistry and Molecular Biology, 2001. http://arrow.monash.edu.au/hdl/1959.1/8876.

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2

Agrotis, Alexander George. "The regulation of human autophagy by ATG4 proteases." Thesis, University College London (University of London), 2018. http://discovery.ucl.ac.uk/10048926/.

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Autophagy is an important intracellular degradation pathway that delivers cytoplasmic material to lysosomes via double-membrane organelles called autophagosomes. Lipidation of ubiquitin- like LC3/GABARAP proteins on the autophagosome membrane is essential for autophagy. The cysteine protease ATG4 executes C-terminal processing (priming) of newly-synthesised LC3/GABARAP to enable subsequent lipidation. ATG4 is also proposed to be important for deconjugating/delipidating LC3/GABARAP from autophagosome membranes, although the ex- act purpose of this is unclear in mammals. Four ATG4 isoforms (ATG4

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3

Ranjit, Najju. "Characterisation of proteases involved in proteolytic degradation of haemoglobin in the human hookworm Necator americanus." Thesis, Queensland University of Technology, 2008. https://eprints.qut.edu.au/20651/1/Najju_Ranjit_Thesis.pdf.

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With over a billion people infected world wide, hookworms are considered as important human pathogens, particularly in developing countries which have the highest rates of infections. Hookworms reside in the gastrointestinal tract of the host where they continuously feed on blood, leading to conditions such as chronic irondeficiency anaemia. The majority of blood-feeding parasites rely on proteins found in blood to provide many of their nutritional requirements for growth, reproduction and survival. Of the numerous proteins found in blood, haemoglobin (Hb) is one of the most abundant. In order

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4

Ranjit, Najju. "Characterisation of proteases involved in proteolytic degradation of haemoglobin in the human hookworm Necator americanus." Queensland University of Technology, 2008. http://eprints.qut.edu.au/20651/.

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With over a billion people infected world wide, hookworms are considered as important human pathogens, particularly in developing countries which have the highest rates of infections. Hookworms reside in the gastrointestinal tract of the host where they continuously feed on blood, leading to conditions such as chronic irondeficiency anaemia. The majority of blood-feeding parasites rely on proteins found in blood to provide many of their nutritional requirements for growth, reproduction and survival. Of the numerous proteins found in blood, haemoglobin (Hb) is one of the most abundant. In order

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5

Gonzalez, Santana Bibiana. "Cysteine proteases: potential serodiagnostic reagents for human Schistosomiasis and Fasciolosis." Thesis, McGill University, 2012. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=110691.

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Schistosomiasis and fasciolosis are parasitic diseases that affect a great number of people, particularly in developing countries, and cause huge global morbidity. Diagnosis is essential for control, treatment and prognosis of the diseases and yet a simple, cheap, sensitive and specific assay is not readily available for either of them. In the current study, cathepsin B (SmCB) and cathepsin L1 (FhCL1) were investigated as potential diagnostic reagents to detect schistosomiasis and fasciolosis, respectively, in humans. The genes encoding SmCB and FhCL1 were expressed Pichia pastoris and the pro

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6

Riddick, Antony C. P. "Expression profiling of proteases and related genes in human prostate tumours." Thesis, University of East Anglia, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.398820.

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7

Gast, Alain. "Proteases et emphyseme pulmonaire : etude des inhibiteurs de proteases recueillis par lavage bronchoalveolaire." Université Louis Pasteur (Strasbourg) (1971-2008), 1987. http://www.theses.fr/1987STR13070.

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8

Wang, Bingjie. "Novel function of human beta-defensin 2 : protecting epidermal barrier against pathogenic proteases." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/28756.

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Atopic Dermatitis (AD) is a common chronic relapsing inflammatory skin disease affecting 15 - 20% of children and 2 - 10% of adults worldwide, with significant morbidity. A hallmark of AD is disruption of the critical barrier function of upper epidermal layers, causatively linked to environmental stimuli, genetics and infections. Another typical feature of AD is skin infections, especially from Staphylococcus aureus (S. aureus), which closely relates with the disease severity. Although not a normal flora, S. aureus is found on 75-100% of AD lesions (< 30% on healthy skin). S. aureus secrete a

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9

West, Andrew. "Investigations by mass spectrometry of the interactions of novel serine protease inhibitors with herpes simplex virus type 2 and human cytomegalovirus proteases." Thesis, University of Warwick, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.343830.

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10

Mulloy, Rory. "Identification of Transmembrane and Extracellular Host Proteases that Promote Human CoV Entry and Syncytium Formation." Thesis, Université d'Ottawa / University of Ottawa, 2021. http://hdl.handle.net/10393/42673.

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