Relevant bibliographies by topics / Human knee osteoarthritis

Academic literature on the topic 'Human knee osteoarthritis'

Author: Grafiati
Published: 10 December 2022
Last updated: 28 January 2023

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Journal articles on the topic "Human knee osteoarthritis"

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Myszka, Anna, Janusz Piontek, Jacek Tomczyk, and Marta Zalewska. "Osteoarthritis – a problematic skeletal trait in past human populations. Osteoarthritic changes vs. entheseal changes in the late medieval and early modern population form Łekno." Anthropological Review 83, no. 2 (June 1, 2020): 143–61. http://dx.doi.org/10.2478/anre-2020-0011.

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AbstractAccording to medical knowledge, physical activity plays a role in osteoarthritic changes formation. The impact of occupation on osteoarthritic changes development in past human populations is not clear enough, causing problems with interpretation. The aim of the current study is to examine the relationship between osteoarthritis and entheseal changes. Skeletal material comes from the late medieval, early modern population from Łekno (Poland). The sample consists of 110 males and 56 females (adults only). Osteophytes, porosity and eburnation were analyzed in the shoulder, elbow, wrist, hip, knee, and ankle. Entheses on the humerus, radius, femur, and tibia were examined. Standard ranked categorical scoring systems were used for the osteoarthritic and entheseal changes examination.Males with more developed osteophytes in the shoulder have more “muscular” upper limbs (higher values of muscle markers). Males with more developed osteophytes in the hip and knee are predicted to have more “muscular” lower limbs. Males with more developed osteoarthritis in the shoulder, wrist, hip, and knee exhibit more developed entheseal changes. Males with more developed entheses tend to yield more developed osteophytes (all joints taken together) and general osteoarthritis (all changes and all joints taken together). Females with more developed entheses have more developed osteoarthritis in the elbow, wrist, and hip. Individuals with more developed entheses have much more developed osteophytes. When all the three types of changes are taken together, more “muscular” females exhibit more developed osteoarthritis. The lack of uniformity of the results, wild discussions on the usage of entheses in activity patterns reconstruction and other limitations do not allow to draw unambiguous conclusions about the impact of physical activity on the osteoarthritis in past populations and further studies are needed.
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Kanthavel, R., and R. Dhaya. "PROGRESS AND PRECLUSION OF KNEE OSTEOARTHRITIS: A STUDY." September 2021 3, no. 3 (September 27, 2021): 150–62. http://dx.doi.org/10.36548/jitdw.2021.3.001.

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There is a need for better medical and preclinical instruments to diagnose knee OA in its initial phases owing to the increase occurrence of knee osteoarthritis (OA), a devastating knee joint degeneration. Osteoarthritis commonly affects patients who are obese and those above the age of 60. This mainly happens to age down and over-weighted people. The goal is to provide practical methods for assessing the seriousness of knee OA quickly and with human consistency. We also present Changes that affect your chances of getting sick of knee osteoarthritis, Treatment of knee osteoarthritis and the Prevention methods of knee osteoarthritis.
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Tarniţă, Daniela, Marius Catana, and Dan Tarnita. "Stresses and Displacements for Virtual Models of Healthy and Osteoarthritic Knee Joint." Applied Mechanics and Materials 658 (October 2014): 526–31. http://dx.doi.org/10.4028/www.scientific.net/amm.658.526.

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This paper presents advanced modeling and simulation methods, using the latest generation of CAD-CAE applications. For the geometric modeling of human knee joint embedded applications as DesignModeler, SpaceClaim under Ansys Workbench software package were used. The objective of this study is to present our contributions on the modeling, simulations and finite element analysis of the healthy and osteoarthritic human knee joint in order to quantify and investigate its biomechanical behavior. The main objective of this article is to present a complex three-dimensional model of the healthy knee joint and of the osteoarthritic joint which shows a 15otilt in varus, the joint being affected by osteoarthritis in both compartments, in order to predict stresses and displacements in their individual components. The applied forces were equal with 800 N and 1500 N. Finally the results obtained for normal knee and for OA knee joint are compared.
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Tan, Jay-Shian, Behrouz Khabbaz Beheshti, Tara Binnie, Paul Davey, J. P. Caneiro, Peter Kent, Anne Smith, Peter O’Sullivan, and Amity Campbell. "Human Activity Recognition for People with Knee Osteoarthritis—A Proof-of-Concept." Sensors 21, no. 10 (May 12, 2021): 3381. http://dx.doi.org/10.3390/s21103381.

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Clinicians lack objective means for monitoring if their knee osteoarthritis patients are improving outside of the clinic (e.g., at home). Previous human activity recognition (HAR) models using wearable sensor data have only used data from healthy people and such models are typically imprecise for people who have medical conditions affecting movement. HAR models designed for people with knee osteoarthritis have classified rehabilitation exercises but not the clinically relevant activities of transitioning from a chair, negotiating stairs and walking, which are commonly monitored for improvement during therapy for this condition. Therefore, it is unknown if a HAR model trained on data from people who have knee osteoarthritis can be accurate in classifying these three clinically relevant activities. Therefore, we collected inertial measurement unit (IMU) data from 18 participants with knee osteoarthritis and trained convolutional neural network models to identify chair, stairs and walking activities, and phases. The model accuracy was 85% at the first level of classification (activity), 89–97% at the second (direction of movement) and 60–67% at the third level (phase). This study is the first proof-of-concept that an accurate HAR system can be developed using IMU data from people with knee osteoarthritis to classify activities and phases of activities.
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Lin, Zhijin, and Ling He. "Intra-Articular Injection of PRP in the Treatment of Knee Osteoarthritis Using Big Data." Journal of Healthcare Engineering 2021 (October 26, 2021): 1–10. http://dx.doi.org/10.1155/2021/4504155.

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Observing data on the characteristics of intra-articular injection of sodium citrate for knee osteoarthritis is an important reference value for human safety and evacuation design. To address the problems of slow data collection and poor accuracy of results of knee osteoarthritis behavior, under intensive conditions of intra-articular injection for knee osteoarthritis, this paper designs a data mining-based feature extraction system for intra-articular injection of sodium citrate for knee osteoarthritis. Using the Hadoop architecture, we extract the basic data of human behavior in the two-dimensional plane by storing and stitching the collected continuous data and discriminate the behavioral categories of knee osteoarthritis. We collected a real dataset from 84 patients with knee osteoarthritis treated in our hospital from October 2019 to October 2020. The dataset was divided into 42 patients in the tretinoin group and 42 patients in the sodium glutamate group according to the randomized number table method. The trimethoprim group was treated with intra-articular injection of trimethoprim, and the sodium citrate group was treated with intra-articular injection of sodium citrate. The clinical efficacy, joint mobility, intra-articular fluid volume, Lysholm score of knee joint, numerical pain intensity scale (NRS) score, and adverse effects of the two groups were compared before and after treatment. In our experiments, we observed that, compared with triamcinolone acetonide intra-articular injection, sodium hyaluronate intra-articular injection is more effective in the treatment of knee osteoarthritis. It can effectively improve knee function and reduce pain and adverse reactions.
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Wang, Pei, Jonas Balko, Rui Lu, Ángela I. López-Lorente, Lutz Dürselen, and Boris Mizaikoff. "Analysis of human menisci degeneration via infrared attenuated total reflection spectroscopy." Analyst 143, no. 20 (2018): 5023–29. http://dx.doi.org/10.1039/c8an00924d.

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Yamamoto, K., T. Shishido, T. Masaoka, and A. Imakiire. "Morphological Studies on the Ageing and Osteoarthritis of the Articular Cartilage in C57 Black Mice." Journal of Orthopaedic Surgery 13, no. 1 (April 2005): 8–18. http://dx.doi.org/10.1177/230949900501300103.

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Purpose. To study the cause and mechanism of joint degeneration in osteoarthritis, through histopathological and ultrastructural-histochemical experiments on the articular cartilage of the knees of the C57 black mouse. Methods. 192 C57 black mice and a control group of 64 C57BL/6J mice were used in this study. The left and right knee articular capsules of the joints were removed and stained. Each articular cartilage sample was examined and osteoarthritic changes were assessed using a transmission electron microscope. The severity of osteoarthritis in the knee joint cartilage of C57 black mice was histologically assessed using a classification system described by Okabe, based on Maier's system. Results. The incidence and the severity of osteoarthritis gradually increased with age; the incidence increased from 20% at 2 months to 80% at 16 months. Irreversible changes appeared at an advanced stage, and the process of degeneration was quite similar to that in human osteoarthritis. Through transmission electron microscopy, we observed poorly developed Golgi apparatus, markedly increased intracellular microfilaments, decreased proteoglycan granules, and broken collagen networks in all stages of osteoarthritis. By contrast, Golgi apparatus and other organelles were well developed in histologically normal mice of all ages. Proteoglycan granules, which mainly consisted of keratan sulphate, were observed; collagen networks were maintained. Conclusion. Disturbed protein transport and sugar synthesis in chondrocytes, caused by the deficient development of the Golgi apparatus, could result in degenerative changes in articular cartilage. The structure and function of the matrix were maintained mainly because of the continued presence of keratan sulphate.
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Catana, Marius, Daniela Tarniţă, and Dan Tarnita. "Modeling, Simulation and Optimization of a Human Knee Orthotic Device." Applied Mechanics and Materials 371 (August 2013): 549–53. http://dx.doi.org/10.4028/www.scientific.net/amm.371.549.

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In order to improve the quality of human walking, the present paper is analyzing a 3D virtual model for an orthotic device which is subjected to an optimization process based on dimensional, geometric and material criteria. For geometric modeling of the human knee joint were used the embedded applications: DesignModeler, SpaceClaim under AnsysWorkbench software package and for the orthotic device it was used ProEngineer application. The orthotic device is designed to rehabilitate people with knee problems, especially for the osteoarthritis affection. The geometric model of the joint shows a 50tilt invarus, the joint beeing affected by osteoarthritis in the medial compartment. Using Ansys simulation environment, the virtual assembly joint orthois has been subjected to a nonlinear analysis based on the contacts and on the materials used. The proposed orthotic device seeks to improve the quality of walking by minimizing the loads from the knee joint, also on cartilage and on the menisci. Finally there are beeing compared the results obtained for normal knee, OA knee and OA knee-orthosis assemblies.
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Rosita, Primadita Esther, Patricia Maria Kurniawati, and Dwikora Novembri Utomo. "Profile of Age, Gender, and Body Mass Index in Patient with Knee Osteoarthritis in Surabaya." Surabaya Physical Medicine and Rehabilitation Journal 3, no. 1 (February 25, 2021): 23. http://dx.doi.org/10.20473/spmrj.v3i1.22355.

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Background: Osteoarthritis is a degenerative disease which attacks all the joint parts, including articular cartilage, subchondral bone, ligament, meniscus, capsule, synovium, and periarticular tissue. Among various joints in human body, knee joint is the most affected by osteoarthritis. There are several established risk factors for knee osteoarthritis, including age, female gender, and obesity.Aim: This study aimed to describe age, gender, and body mass index (BMI) profile in knee osteoarthritis patients.Material and methods: This was a retrospective descriptive study with total sampling of 292 medical records of patient with knee osteoarthritis from Physical Medicine and Rehabilitation outpatient clinic, Universitas Airlangga Hospital, Surabaya.Results: Of all the data, there were 130 medical records included in this study. The majority characteristic of the subjects were older than 60 years old (54.6%), 98 (75.4%) were females and 32 (24.6%) were males. The highest male-female ratio was on 45-59 years old (1:4). Most patients were obese (58.5%) with the highest percentage was on 45-59 years old (51.3%).Conclusion: The majority of osteoarthritis patients in Universitas Airlangga Hospital Surabaya were elderly, females, and obese people.
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Nakagawa, Yasuaki, Shogo Mukai, Shigeru Yamada, Satoru Murata, Hiromitsu Yabumoto, Takahiro Maeda, and Shota Akamatsu. "The Efficacy and Safety of Highly-Bioavailable Curcumin for Treating Knee Osteoarthritis: A 6-Month Open-Labeled Prospective Study." Clinical Medicine Insights: Arthritis and Musculoskeletal Disorders 13 (January 2020): 117954412094847. http://dx.doi.org/10.1177/1179544120948471.

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Background: We previously developed a surface-controlled water-dispersible form of curcumin that we called Theracurmin®. The area under the blood concentration-time curve (AUC) of Theracurmin in humans was 27-fold higher than that of curcumin powder. Previously, we reported on the anti-inflammatory effects of Theracurmin for knee osteoarthritis. Hypothesis/Purpose: We determined the clinical effects of orally administered Theracurmin in patients with knee osteoarthritis over a 6-month period. Study Design: Open prospective study. Methods: Fifty patients Kellgren-Lawrence grade II, III, or IV knee osteoarthritis who were above 40 years old were enrolled in this clinical study. Theracurmin containing 180 mg/day of curcumin was administered orally every day for 6 months. To monitor for adverse events, blood biochemistry analyses were performed before and after 6 months of each intervention. The patients’ knee symptoms were evaluated at 0, 1, 2, 3, 4, 5, and 6 months based on the Japanese Knee Osteoarthritis Measure, the knee pain visual analog scale, and the knee scoring system of the Japanese Orthopedic Association. Results: Five cases dropped out during the study, but no cases dropped out because of major problems. No major side effects were observed with Theracurmin treatment, including the blood biochemistry analysis results. The effective group included 34 cases (75.6%), while the not-effective group included 11 cases. Conclusion: This study demonstrates the safety and good efficacy of Theracurmin for various types of knee osteoarthritis. Theracurmin shows great potential for the treatment of human knee osteoarthritis.
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Dissertations / Theses on the topic "Human knee osteoarthritis"

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Gikas, P. "A study of the subchondral bone in human knee osteoarthritis using Raman spectroscopy." Thesis, University College London (University of London), 2013. http://discovery.ucl.ac.uk/1403229/.

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Osteoarthritis (OA) is a common, debilitating disease, involving degeneration of cartilage and bone in synovial joints. Subtle changes in the molecular structure of subchondral bone matrix occur and may precede gross morphological changes in the osteoarthritic joint. In this thesis, the analytical technique Raman Spectroscopy (which uses a monochromatic light source to probe chemical composition) is used to explore the hypothesis that subchondral bone changes occur prior to and during joint degeneration. The question is approached by looking at excised tibial plateaus from patients undergoing total knee replacement for advanced OA of the knee and comparing them with tibial plateaus from healthy joints. The samples were analysed with Raman spectroscopy, peripheral quantitative computed tomography (pQCT) and chemical analysis, to compare collagen alpha chains. The results show that bone matrix changes, related to OA, can be detected in the subchondral bone prior to overt cartilage damage, by Raman spectroscopy. These data provide support that chemical changes in bone can be related to the initiation of, or predisposition towards, joint degeneration. The results demonstrate that Raman spectroscopy should be further developed as a future tool to provide screening for early detection of joint degeneration based on correlating molecular-specific modifications in the subchondral bone.
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Heiden, Tamika Louise. "Neuromuscular-biomechanical outcomes of different types of resistance training on people with knee osteoarthritis." University of Western Australia. School of Sport Science, Exercise and Health, 2009. http://theses.library.uwa.edu.au/adt-WU2010.0066.

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[Truncated abstract] Knee osteoarthritis (OA) patients have high levels of pain, functional and strength deficits of the quadriceps, decreased proprioceptive acuity, and increased co-contraction and knee joint loading in gait, compared to age matched controls. The increased knee joint loading in this population occurs most commonly in the medial tibio-femoral compartment, due to increased external adduction moments, and with increasing disease severity there is a concomitant increase in the knee adduction moments. A key finding within the knee OA literature is that dynamic loading in gait, due to increased external adduction moments, strongly predicts pain and radiographic disease progression. Current research has shown that exercise interventions reduce pain and time to complete functional activities; however, the effect of these interventions on knee joint loading and muscular activation in gait is still unclear. In addition, the need for specific knee joint strengthening to cause these alterations has not been investigated and it remains unknown if improvements occur due to specific muscle strengthening or due to some general effect of exercise. Therefore, the primary aim of this research study was to examine the effects of general (upper body) and specific (lower body) resistance training interventions on self-perceived outcomes, neuromuscular function and kinematic, kinetic and muscle activation during gait of OA patients compared with asymptomatic controls. ... The examination of gait data following exercise (Study 4) showed trends for changes in the muscle co-contraction ratios. Specifically, the medial/lateral co-contraction ratio (MLCCR) displayed a trend in early stance where the upper body exercise group increased their lateral muscle activity and the lower body group reduced their lateral muscle activity, and the medial/lateral hamstring co-contraction ratio (HAMCCR) displayed this same trend during loading. The trend toward reduced lateral muscle activation, following lower body resistance training, suggests that specific muscle strengthening may have the ability to alter the load distribution. The kinematic and kinetic variables of gait were unchanged by the exercise interventions, highlighting the sensitivity of muscle activation pattern changes due to muscle strengthening. This thesis provides new insights into the co-contraction strategies utilised by knee OA patients. The directed co-contraction strategy employed by knee OA patients and its relationship to the external adduction moment in gait suggest an attempt to redistribute the loading within the knee joint, most likely in response to pain. Further, we have separated the effects of exercise and found differences in self-perceived outcomes based on exercise specificity. This first examination into muscle co-contraction following resistance training of knee OA patients has highlighted the possibility of alterations to the co-contraction patterns following lower body exercise. However, the implications of altering this muscle activation strategy and the consequent effect on distribution of load within the knee joint requires further consideration.
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Lane, Gregory. "Human Knee FEA Model for Transtibial Amputee Tibial Cartilage Pressure in Gait and Cycling." DigitalCommons@CalPoly, 2018. https://digitalcommons.calpoly.edu/theses/1833.

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Osteoarthritis (OA) is a debilitating disease affecting roughly 31 million Americans. The incidence of OA is significantly higher for persons who have suffered a transtibial amputation. Abnormal cartilage stress can cause higher OA risk, however it is unknown if there is a connection between exercise type and cartilage stress. To help answer this, a tibiofemoral FEA model was created. Utilizing linear elastic isotropic materials and non-linear springs, the model was validated to experimental cadaveric data. In a previous study, 6 control and 6 amputee subjects underwent gait and cycling experiments. The resultant knee loads were analyzed to find the maximum compressive load and the respective shear forces and rotation moments for each trial, which were then applied to the model. Maximum tibial contact stress values were extracted for both the medial and lateral compartments. Only exercise choice in the lateral compartment was found to be a significant interaction (p<0.0001). No other interactions in either compartment were significant. This suggests that cycling reduces the risk for lateral OA regardless of amputation status and medial OA risk is unaffected. This study also developed a process for creating subject-specific FEA models.
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Bocking, George. "The use of phonoarthrometry to detect osteoarthritis in the human knee joint : a clinical proof of concept study." Thesis, Anglia Ruskin University, 2013. http://arro.anglia.ac.uk/701465/.

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The potential clinical value of sounds and vibrations produced by joints as they move has been studied extensively since 1902 however as of yet no clinically useful device exists. The phonoarthrometer is an experimental prototype diagnostic tool which has the potential to detect joint disorders through interpretation of the sounds produced when the knee joint is moved naturally. The study aims to evaluate the phonoarthrometers’ clinical usefulness through its ability to detect osteoarthritis of the human knee joint. Investigation of the phonoarthrometers’ ability to detect osteoarthritis involved taking the prototype device into a clinical environment and using it to test osteoarthritic affected knee joints. A dataset from knee joints defined as normal was also collected for use in the building of the core microstructure database and for use as a comparative control group. The vibration signal of the knee joint was collected via accelerometer sensors placed at the patella and a medial joint line. An electro-goniometer was used to collect the angular data of the knee in motion. All participants were required to complete a set of test protocols designed to gather both loaded and unloaded data from the knee joint. Collected data was then analysed using the phonoarthrometer software. The phonoarthrometer was able to differentiate an osteoarthritic knee vibration response from a healthy normal knee response. This manifested as a greater level of suppression in the vibration response from the osteoarthritic knee group compared with the normal knee group. Detection between medial and lateral compartment osteoarthritis was possible due to differences in the suppression level of the vibration signal. Determination of the severity of the osteoarthritis in the affected knee was not consistent enough to be conclusive. The phonoarthrometer in its current state of development would be limited in its usefulness as a diagnostic device. Further improvements to its detection ability are needed to allow the level of detail needed for a clinically useful diagnosis.
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Bocking, George. "The use of Phonoarthrometry to detect Osteoarthritis in the Human Knee Joint: A Clinical Proof of Concept Study." Thesis, Anglia Ruskin University, 2013. https://arro.anglia.ac.uk/id/eprint/701465/1/Bocking_2013.pdf.

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The potential clinical value of sounds and vibrations produced by joints as they move has been studied extensively since 1902 however as of yet no clinically useful device exists. The phonoarthrometer is an experimental prototype diagnostic tool which has the potential to detect joint disorders through interpretation of the sounds produced when the knee joint is moved naturally. The study aims to evaluate the phonoarthrometers’ clinical usefulness through its ability to detect osteoarthritis of the human knee joint. Investigation of the phonoarthrometers’ ability to detect osteoarthritis involved taking the prototype device into a clinical environment and using it to test osteoarthritic affected knee joints. A dataset from knee joints defined as normal was also collected for use in the building of the core microstructure database and for use as a comparative control group. The vibration signal of the knee joint was collected via accelerometer sensors placed at the patella and a medial joint line. An electro-goniometer was used to collect the angular data of the knee in motion. All participants were required to complete a set of test protocols designed to gather both loaded and unloaded data from the knee joint. Collected data was then analysed using the phonoarthrometer software. The phonoarthrometer was able to differentiate an osteoarthritic knee vibration response from a healthy normal knee response. This manifested as a greater level of suppression in the vibration response from the osteoarthritic knee group compared with the normal knee group. Detection between medial and lateral compartment osteoarthritis was possible due to differences in the suppression level of the vibration signal. Determination of the severity of the osteoarthritis in the affected knee was not consistent enough to be conclusive. The phonoarthrometer in its current state of development would be limited in its usefulness as a diagnostic device. Further improvements to its detection ability are needed to allow the level of detail needed for a clinically useful diagnosis.
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Wangerin, Spencer D. "Development and validation of a human knee joint finite element model for tissue stress and strain predictions during exercise." DigitalCommons@CalPoly, 2013. https://digitalcommons.calpoly.edu/theses/1129.

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Osteoarthritis (OA) is a degenerative condition of cartilage and is the leading cost of disability in the United States. Motion analysis experiments in combination with knee-joint finite element (FE) analysis may be used to identify exercises that maintain knee-joint osteochondral (OC) loading at safe levels for patients at high-risk for knee OA, individuals with modest OC defects, or patients rehabilitating after surgical interventions. Therefore, a detailed total knee-joint FE model was developed by modifying open-source knee-joint geometries in order to predict OC tissue stress and strain during the stance phase of gait. The model was partially validated for predicting the timing and locations of maximum contact parameters (contact pressure, contact area, and principal Green-Lagrangian strain), but over-estimated contact parameters compared with both published in vivo studies and other FE analyses of the stance phase of gait. This suggests that the model geometry and kinematic boundary conditions utilized in this FE model are appropriate, but limitations in the material properties used, as well as potentially the loading boundary conditions represent primary areas for improvement.
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Crenshaw, Jeremy. "Knee-joint loading variability during gait in subjects with knee osteoarthritis." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 42 p, 2007. http://proquest.umi.com/pqdweb?did=1338917851&sid=5&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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Czapla, Nicholas. "Development and Validation of a Tibiofemoral Joint Finite Element Model and Subsequent Gait Analysis of Intact ACL and ACL Deficient Individuals." DigitalCommons@CalPoly, 2015. https://digitalcommons.calpoly.edu/theses/1488.

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Osteoarthritis (OA) is a degenerative condition of articular cartilage that affects more than 25 million people in the US. Joint injuries, like anterior cruciate ligament (ACL) tears, can lead to OA due to a change in articular cartilage loading. Gait analysis combined with knee joint finite element modeling (FEM) has been used to predict the articular cartilage loading. To predict the change of articular cartilage loading during gait due to various ACL injuries, a tibiofemoral FEM was developed from magnetic resonance images (MRIs) of a 33 year male, with no prior history of knee injuries. The FEM was validated for maximum contact pressure and anterior tibial translation using cadaver knee studies. The FEM was used to model gait of knees with an intact ACL, anteromedial (AM) bundle injury, posterolateral (PL) bundle injury, complete ACL injury, AM deficiency, PL deficiency, complete ACL rupture, as well as a bone-patellar tendon-bone (BPTB) graft. Generally, the predicted maximum contact pressure and contact area increased for all the ACL injuries when compared to intact ACLs. While an increase in maximum contact pressure and contact area is an indication of an increased risk of the development of OA, the percent of increase was typically small suggesting that walking is a safe activity for individuals with ACL injuries.
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Robin, Joshua B. "A paleopathological assessment of osteoarthritis in the lower appendicular joints of individuals from the Kellis 2 cemetery in the Dakhleh Oasis, Egypt." Master's thesis, University of Central Florida, 2011. http://digital.library.ucf.edu/cdm/ref/collection/ETD/id/4703.

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Osteoarthritis (OA) is a degenerative pathological condition of the appendicular joints which affects the cartilage and underlying bone. OA is relatively common in both the archaeological and clinical context, and a significant amount of research has been conducted on this osteological condition. The purpose of this thesis is to assess the incidence, demographic prevalence, and general severity of hip and knee OA in a Roman-Christian period (50 A.D-450 A.D) population sample from the Dakhleh Oasis, Egypt. The bioarchaeological sample originates from the Kellis 2 cemetery which is associated with the ancient town of Kellis. The town of Kellis is believed to have been a prosperous economic hub in Egypt, located in the Western Sahara Desert approximately 250 kilometers west of the Nile. The skeletal samples (n=135, 83 females and 51 males) was visually assessed for the osteological characteristics of OA in the hips and the knees. Joint surfaces of the hip include the acetabulum and femoral head. Joint surfaces of the knee include lateral/medial tibio-femoral compartments and the patellofemoral compartment. The ages of the individuals assessed in this study range from 19-72 years, and have been divided into five age categories which were then cross-tabulated with sex and OA incidence in order to determine demographic prevalence of OA. Findings indicate that age is a significant etiological factor of OA prevalence for both males and females. Males are afflicted by the disease significantly more than females in the hips (F: (L) 3.6%, (R) 5.9% and M: (L) 13.7%, (R) 13.7%) and also slightly more affected in the knees(F: (L) 17.5%, (R) 18.3% and M: (L) 22.9%, (R)21.3%). The acetabulum tends to be more arthritic than the femoral head for both males and females. Femoral condyles tend to be more arthritic than tibial condyles for both males and females.; The patello-femoral compartment tends to be the most arthritic part of the knee while the medial condyles of both tibiae exhibit virtually no OA (with the exception of one individual). The joint surface observed with the highest OA prevalence is the femoral surface of the patella (F: (L) 17.5%, (R) 15.9% and M: (L) 21.3%, (R) 21.3%). The highest prevalence of OA by joint complex is observed on the left knee in males (22.9%), and the lowest prevalence of OA is observed on the left hip of females (3.6%). Both hip and knee joints have higher prevalence of unilateral OA manifestation than bilateral. Isotopic and archaeological evidence indicates that the individuals at Kellis maintained an agricultural subsistence regime, and that the males within the population may have been highly mobile migrating to and from the Dakhleh Oasis. Subsistence agriculture has its necessary physical demands which may have been a contributory factor to OA rates. Males show higher OA rates than females throughout the joints of the legs. Sexual dimorphism of OA for the hips is suggestive of sexual divisions of labor. OA of the knees lacks sexual dimorphism therefore the knee joint complex of males and females were likely subjected to similar levels of mechanical loading. It can be concluded based on the OA data that males and females exhibit similar activity, or biomechanical stress levels in the knee joint complexes. Males exhibit significantly higher pathological manifestation of OA in the hip joint complexes, indicative of higher levels of mechanical loading in the hip joint complex which can theoretically be attributed to sexual divisions of labor or perhaps terrestrial mobility.
ID: 030646221; System requirements: World Wide Web browser and PDF reader.; Mode of access: World Wide Web.; Thesis (M.A.)--University of Central Florida, 2011.; Includes bibliographical references.
M.A.
Masters
Anthropology
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Anthropology
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Briem, Kristin. "Gait and function in knee osteoarthritis effects of hyaluronan injection /." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 183 p, 2008. http://proquest.umi.com/pqdweb?did=1601513361&sid=6&Fmt=2&clientId=8331&RQT=309&VName=PQD.

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Books on the topic "Human knee osteoarthritis"

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Maquet, Paul G. J. Biomechanics of the Knee: With Application to the Pathogenesis and the Surgical Treatment of Osteoarthritis. Springer, 2012.

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Book chapters on the topic "Human knee osteoarthritis"

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Wu, Fong-Gong, and Hsien-Chi Kuo. "Design of an Innovative Assisting Device for Knee Osteoarthritis." In Universal Access in Human–Computer Interaction. Human and Technological Environments, 117–25. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-58700-4_11.

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Aurich, Matthias E., Jürgen A. Mollenhauer, Klaus E. Kuettner, and Ada A. Cole. "Differential effects of IL-1β on human knee and ankle chondrocytes." In The Many Faces of Osteoarthritis, 429–32. Basel: Birkhäuser Basel, 2002. http://dx.doi.org/10.1007/978-3-0348-8133-3_42.

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Hubley-Kozey, Cheryl L., and Janie Astephen Wilson. "Effects of Knee Osteoarthritis and Joint Replacement Surgery on Gait." In Handbook of Human Motion, 1521–49. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-14418-4_82.

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Hubley-Kozey, Cheryl L., and Janie Astephen Wilson. "Effects of Knee Osteoarthritis and Joint Replacement Surgery on Gait." In Handbook of Human Motion, 1–29. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-30808-1_82-1.

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Tarnita, D., M. Catana, and D. N. Tarnita. "Nonlinear Analysis of Osteoarthritis Process in Virtual Human Knee Joint." In The 11th IFToMM International Symposium on Science of Mechanisms and Machines, 223–31. Cham: Springer International Publishing, 2013. http://dx.doi.org/10.1007/978-3-319-01845-4_23.

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Poole, A. R., G. Rizkalla, M. Ionescu, A. Reiner, E. Brooks, C. Rorabeck, R. Bourne, and E. Bogoch. "Osteoarthritis in the Human Knee: A Dynamic Process of Cartilage Matrix Degradation, Synthesis and Reorganization." In Joint Destruction in Arthritis and Osteoarthritis, 3–13. Basel: Birkhäuser Basel, 1993. http://dx.doi.org/10.1007/978-3-0348-7442-7_1.

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Gong, Zidan, Rong Liu, Winnie Yu, Thomas Wong, and Yuanqi Guo. "Preliminary Therapeutic Knee Band Development for Knee Osteoarthritis (KOA) Relief in the Elderly: A Pilot Study." In Advances in Human Factors in Wearable Technologies and Game Design, 111–22. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-94619-1_11.

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Awbrey, Brian J., Sharon J. Kuong, K. L. MacNeil, and Marianne Wright. "The Role of Alpha-1-Protease Inhibitor (A1PI) in the Inhibition of Protease Activity in Human Knee Osteoarthritis." In Joint Destruction in Arthritis and Osteoarthritis, 167–71. Basel: Birkhäuser Basel, 1993. http://dx.doi.org/10.1007/978-3-0348-7442-7_19.

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Tarnita, Daniela, Marius Georgescu, and Alin Petcu. "On the Measurement of Dynamic Stability of Normal and Osteoarthritic Human Knee During Ascending and Descending the Stairs." In New Advances in Mechanisms, Mechanical Transmissions and Robotics, 543–55. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-60076-1_49.

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Spain, Lucy, and David Cheneler. "Acoustic Monitoring of Joint Health." In Data Acquisition - Recent Advances and Applications in Biomedical Engineering. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.92868.

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The joints of the human body, especially the knees, are continually exposed to varying loads as a person goes about their day. These loads may contribute to damage to tissues including cartilage and the development of degenerative medical conditions such as osteoarthritis (OA). The most commonly used method currently for classifying the severity of knee OA is the Kellgren and Lawrence system, whereby a grade (a KL score) from 0 to 4 is determined based on the radiographic evidence. However, radiography cannot directly depict cartilage damage, and there is low inter-observer precision with this method. As such, there has been a significant activity to find non-invasive and radiation-free methods to quantify OA, in order to facilitate the diagnosis and the appropriate course of medical action and to validate the development of therapies in a research or clinical setting. A number of different teams have noted that variation in knee joint sounds during different loading conditions may be indicative of structural changes within the knee potentially linked to OA. Here we will review the use of acoustic methods, such as acoustic Emission (AE) and vibroarthrography (VAG), developed for the monitoring of knee OA, with a focus on the issues surrounding data collection and analysis.
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Conference papers on the topic "Human knee osteoarthritis"

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Taylor, Portia E., Gustavo J. M. Almeida, Takeo Kanade, and Jessica K. Hodgins. "Classifying human motion quality for knee osteoarthritis using accelerometers." In 2010 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC 2010). IEEE, 2010. http://dx.doi.org/10.1109/iembs.2010.5627665.

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Chen, Yanping, Chunbin Li, Ye Hu, Zhudi Long, and Qianwen Chu. "The study of near infrared spectral characteristics of knee osteoarthritis." In International conference on Human Health and Medical Engineering. Southampton, UK: WIT Press, 2014. http://dx.doi.org/10.2495/hhme130281.

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Huang, Po-Chun, Kai-Chun Liu, Chia-Yeh Hsieh, and Chia-Tai Chan. "Human motion identification for rehabilitation exercise assessment of knee osteoarthritis." In 2017 International Conference on Applied System Innovation (ICASI). IEEE, 2017. http://dx.doi.org/10.1109/icasi.2017.7988396.

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Zahurul, Syed, Syed Zahidul, and Razali Jidin. "An Adept Edge Detection Algorithm for Human Knee Osteoarthritis Images." In 2010 International Conference on Signal Acquisition and Processing (ICSAP). IEEE, 2010. http://dx.doi.org/10.1109/icsap.2010.53.

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Honarmandi, Peyman, and Erwan Malki. "Design of Knee Prosthesis to Sustain ACL/PCL Ligaments and Alleviate Osteoarthritis." In ASME 2021 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/imece2021-72166.

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Abstract As human beings age, their bodies tend to deteriorate. It is the task of an engineer to counteract this natural process to ensure that humans can have a high quality of life for as long as possible. A condition that affects a wide range of people life is a discomfort and pain in the knee. This is most often caused by osteoarthritis, which occurs when the cartilage in the knee deteriorates causing the bones to rub against each other creating extreme discomfort. In this study, the attempt is to design an inexpensive and practical prosthesis to maintain and preserve the patient’s anterior cruciate ligament. The other design goals of this prosthesis are to be manufacturable and applicable by surgeons. Further, the finite element analysis has been conducted to assure the designed prosthesis can withstand the physiological loads applied on knees during daily activities.
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Pfeiler, T. Wayne, Mehran Kasra, Aboulfazi Shirazi-Adl, and Harold E. Cates. "Finite Element Dynamic Response Analysis of the Human Knee Joint." In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-59873.

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Mechanical factors play an important role in the etiology of knee injuries and diseases such as osteoarthritis (OA). While performing daily, occupational, and sport activities, the joint is subjected to dynamic loads such as vibration and multiple impacts. According to an individual’s age, fitness, and weight, these activities may cause the joint load, stiffness, and damping to reach critical limits initiating or accelerating different knee disorders such as osteoarthritis [Wolfe et al., 1996]. Computational models of the knee have been developed over the past several decades. However, these models leave much to be desired, since they often over-simplify the geometry and material properties of the knee. Several two dimensional models have been created [Gill et al., 1996]. Three-dimensional analytical studies have become more common in recent years, and typically model the tibiofemoral joint [Abdel-Rahman et al., 1993; Blankevoort et al, 1991; Wisman et al., 1980]. These studies typically model only surfaces and neglect the effect of ligaments and menisci/cartilage.
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Ali, Neserin, Jon Tjörnstrand, Paul Neuman, Elin Folkesson, Velocity Hughes, Patrik Önnerfjord, and Martin Englund. "THU0415 EXPLORATORY PROTEIN PROFILING OF HUMAN SYNOVIAL FLUID FROM KNEE OSTEOARTHRITIS." In Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12–15 June 2019. BMJ Publishing Group Ltd and European League Against Rheumatism, 2019. http://dx.doi.org/10.1136/annrheumdis-2019-eular.5287.

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Dabiri, Yaghoub, and LePing Li. "A Numerical Model of Mechanics of Osteoarthritis in Human Knee Joint." In ASME 2012 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/imece2012-89225.

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Articular cartilage is composed of water entrapped in a solid matrix formed by proteoglycans and collagen fibers. Therefore, the mechanical behavior of this tissue is determined by all of these three components. In addition, the properties of articular cartilage vary along the depth and by location. In the human knee joint, the three dimensional geometry as well as the contact between the cartilaginous tissues plays essential roles in the joint mechanics. On the other hand, initiation and progression of osteoarthritis (OA) could be partly caused by contact loads. Consequently, the fibrillar and non-fibrillar matrices, the three dimensional geometry and the contact between the tissues should be considered as essential parameters in the study of the mechanics of osteoarthritis. However, previous studies on OA mechanics were mostly limited to explants geometries [1]. Also, the contact mechanics associated with the fluid pressure have not been considered in the previous OA models. In a recent knee model, fluid was considered in femoral cartilage but not in the menisci [2]. Additionally, the depth-dependent mechanical properties were not included in that model.
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Wang, Jaw-Lin, Cheng-Hsien Chung, and Chung-Kai Chiang. "How the External Impact Energy Affects the Internal Kinetics of Knee Joint: The Comparison of Porcine and Human Knee Joint." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-42913.

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Degenerative osteoarthritis is recognized as the consequences of mechanical injuries. The abnormal impact force applied to articular cartilage would result in bone fracture or surface fissuring, and would cause the osteoarthritis [1,2]. The relation among the injury and impact energy was well studied. However, how the external energy attenuated to the internal joint is not carefully studied yet. The porcine knee joint was used as a biomechanical model for the simulation of human knee joint during impact loading. The objective of current study was to find the variation of kinetic characteristics between human and porcine knee joint during axial impact loading. Eight fresh-frozen knee joints from 10 month-old swine and seven cadaver human knee joints were used in the experiment. The mechanical responses such as forces and bending moment of knee joint, and the accelerations of femur was quantitatively analyzed. The results showed that the axial force response between human and porcine joints was similar, however, the anteroposterior shear, flexion bening moment and accelerations of these two joints were different.
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Yu, Chengbo, Yinli Tian, Qiyi Dai, Xichao Zhao, and Shaokui Yan. "Based on the genetic algorithm to optimize the BP neural network of knee osteoarthritis diagnosed." In International conference on Human Health and Medical Engineering. Southampton, UK: WIT Press, 2014. http://dx.doi.org/10.2495/hhme130061.

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