Journal articles on the topic 'Human ILC2 function'
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Lim, Ai Ing, Silvia Menegatti, Jacinta Bustamante, Lionel Le Bourhis, Matthieu Allez, Lars Rogge, Jean-Laurent Casanova, Hans Yssel, and James P. Di Santo. "IL-12 drives functional plasticity of human group 2 innate lymphoid cells." Journal of Experimental Medicine 213, no. 4 (March 14, 2016): 569–83. http://dx.doi.org/10.1084/jem.20151750.
Full textSurace, Laura, Jean-Marc Doisne, Carys A. Croft, Anna Thaller, Pedro Escoll, Solenne Marie, Natalia Petrosemoli, et al. "Dichotomous metabolic networks govern human ILC2 proliferation and function." Nature Immunology 22, no. 11 (October 22, 2021): 1367–74. http://dx.doi.org/10.1038/s41590-021-01043-8.
Full textHurrell, Benjamin P., Doumet Goerges Helou, Pedram Shafiei-Jahani, Emily Diane Howard, Jacob Dean Painter, Christine Quach, and Omid Akbari. "CB2 engagement enhances group 2 innate lymphoid cell expansion and induction of airway hyperreactivity." Journal of Immunology 208, no. 1_Supplement (May 1, 2022): 109.14. http://dx.doi.org/10.4049/jimmunol.208.supp.109.14.
Full textMaazi, Hadi, Homayon Banie, German Aleman, Gavin Lewis, Nisheel Patel, Bowen Wang, Pejman Soroosh, and Omid Akbari. "Toll-like receptor-7-mediated activation of pDCs suppresses the ILC2-mediated airway hyperreactivity and inflammation through type-I interferon." Journal of Immunology 198, no. 1_Supplement (May 1, 2017): 53.7. http://dx.doi.org/10.4049/jimmunol.198.supp.53.7.
Full textHurrell, Benjamin P., Lauriane Galle-Treger, Pedram Shafiei Jahani, Emily Howard, Doumet Georges Helou, Homayon Banie, Pejman Soroosh, and Omid Akbari. "TNFR2 signaling enhances ILC2 survival, function and induction of airway hyperreactivity." Journal of Immunology 204, no. 1_Supplement (May 1, 2020): 60.5. http://dx.doi.org/10.4049/jimmunol.204.supp.60.5.
Full textJowett, G. M., E. Read, M. D. Norman, P. A. Arevalo, M. Vilà González, L. Roberts, L. Vallier, et al. "OP13 Mucosal organoids capture Innate Lymphoid Cells (ILC) tissue-specific development and reveal that Inflammatory Bowel Disease-associated ILC modulate intestinal remodelling." Journal of Crohn's and Colitis 15, Supplement_1 (May 1, 2021): S013—S014. http://dx.doi.org/10.1093/ecco-jcc/jjab075.012.
Full textGalle, Lauriane, Ishwarya Sankaranarayanan, Benjamin P. Hurrell, Emily Howard, Richard Lo, Hadi Maazi, Gavin Lewis, et al. "Costimulation of type-2 innate lymphoid cells by GITR promotes effector function and ameliorates type 2 diabetes." Journal of Immunology 202, no. 1_Supplement (May 1, 2019): 122.10. http://dx.doi.org/10.4049/jimmunol.202.supp.122.10.
Full textKovats, Susan, Sean Turner, Anna Karlik, Reegan Miller, Erola Ainsua-Enrich, and Sapana Kadel. "Androgen receptor activity underlies sex differences in lung-resident ILC2 functional responses during influenza virus infection." Journal of Immunology 204, no. 1_Supplement (May 1, 2020): 85.4. http://dx.doi.org/10.4049/jimmunol.204.supp.85.4.
Full textValdez, Yanet, Stephen K. Kyei, Grace F. T. Poon, Fumio Takei, Carrie Peters, Steve M. Woodside, Allen C. Eaves, and Terry E. Thomas. "Fast and efficient enrichment of functional ILC2 from human whole blood." Journal of Immunology 196, no. 1_Supplement (May 1, 2016): 209.16. http://dx.doi.org/10.4049/jimmunol.196.supp.209.16.
Full textMaazi, Hadi, Nisheel Patel, Ishwarya Sankaranarayanan, Diamanda Riagas, Pejman Soroosh, Gordon Freeman, Arlene Sharpe, and Omid Akbari. "ICOS: ICOS-ligand interaction is essential for ILC2 function and survival (HYP2P.322)." Journal of Immunology 194, no. 1_Supplement (May 1, 2015): 53.3. http://dx.doi.org/10.4049/jimmunol.194.supp.53.3.
Full textDrake, Li Y., Kay Bachman, and Hirohito Kita. "The function of the circulating innate lymphoid cells is dysregulated in patients with mild asthma." Journal of Immunology 202, no. 1_Supplement (May 1, 2019): 119.27. http://dx.doi.org/10.4049/jimmunol.202.supp.119.27.
Full textHardman, Clare S., Yi-Ling Chen, Maryam Salimi, Janina Nahler, Daniele Corridoni, Marta Jagielowicz, Chathuranga L. Fonseka, et al. "IL-6 effector function of group 2 innate lymphoid cells (ILC2) is NOD2 dependent." Science Immunology 6, no. 59 (May 21, 2021): eabe5084. http://dx.doi.org/10.1126/sciimmunol.abe5084.
Full textBlomme, Evy E., Sharen Provoost, Erica Bazzan, Hannelore P. Van Eeckhoutte, Mirjam P. Roffel, Lore Pollaris, Annelies Bontinck, et al. "Innate lymphoid cells in isocyanate-induced asthma: role of microRNA-155." European Respiratory Journal 56, no. 3 (June 4, 2020): 1901289. http://dx.doi.org/10.1183/13993003.01289-2019.
Full textBartemes, Kathleen, Stephanie Fox, and Hirohito Kita. "IL-33- and IL-25-responsive innate lymphoid cells are present in human peripheral blood. (P6237)." Journal of Immunology 190, no. 1_Supplement (May 1, 2013): 181.1. http://dx.doi.org/10.4049/jimmunol.190.supp.181.1.
Full textWang, Yuan Min, Karli Shaw, Geoff Yu Zhang, Edmund Y. M. Chung, Min Hu, Qi Cao, Yiping Wang, et al. "Interleukin-33 Exacerbates IgA Glomerulonephritis in Transgenic Mice Overexpressing B Cell Activating Factor." Journal of the American Society of Nephrology 33, no. 5 (April 6, 2022): 966–84. http://dx.doi.org/10.1681/asn.2021081145.
Full textHelou, Georges Doumet, Pedram Shafiei-Jahani, Richard Lo, Emily Diane Howard, Benjamin P. Hurrell, Lauriane Galle-Treger, Jacob Dean Painter, et al. "PD-1 agonist modulates ILC2 metabolism and ameliorates airway hyperreactivity." Journal of Immunology 208, no. 1_Supplement (May 1, 2022): 109.15. http://dx.doi.org/10.4049/jimmunol.208.supp.109.15.
Full textvan der Ploeg, Esmee K., Ana Carreras Mascaro, Danny Huylebroeck, Rudi W. Hendriks, and Ralph Stadhouders. "Group 2 Innate Lymphoid Cells in Human Respiratory Disorders." Journal of Innate Immunity 12, no. 1 (February 6, 2019): 47–62. http://dx.doi.org/10.1159/000496212.
Full textKonya, Viktoria, and Jenny Mjösberg. "Lipid mediators as regulators of human ILC2 function in allergic diseases." Immunology Letters 179 (November 2016): 36–42. http://dx.doi.org/10.1016/j.imlet.2016.07.006.
Full textMazzurana, Luca, Marianne Forkel, Anna Rao, Aline Van Acker, Efthymia Kokkinou, Tamaki Ichiya, Sven Almer, Charlotte Höög, Danielle Friberg, and Jenny Mjösberg. "Suppression of Aiolos and Ikaros expression by lenalidomide reduces human ILC3–ILC1/NK cell transdifferentiation." Journal of Immunology 202, no. 1_Supplement (May 1, 2019): 187.10. http://dx.doi.org/10.4049/jimmunol.202.supp.187.10.
Full textSui, Pengfei, Darin L. Wiesner, Jinhao Xu, Yan Zhang, Jinwoo Lee, Steven Van Dyken, Amber Lashua, et al. "Pulmonary neuroendocrine cells amplify allergic asthma responses." Science 360, no. 6393 (March 29, 2018): eaan8546. http://dx.doi.org/10.1126/science.aan8546.
Full textDulson, Sarah J., and Laurie E. Harrington. "STAT4 is required for protective Innate Lymphoid Cell responses to gastrointestinal infection." Journal of Immunology 198, no. 1_Supplement (May 1, 2017): 131.1. http://dx.doi.org/10.4049/jimmunol.198.supp.131.1.
Full textCheepsattayakorn, Attapon, and Ruangrong Cheepsattayakorn. "Pulmonary pathology of COVID-19." Journal of Lung, Pulmonary & Respiratory Research 7, no. 3 (November 4, 2020): 79–83. http://dx.doi.org/10.15406/jlprr.2020.07.00234.
Full textMoreno Nieves, Uriel Y., Joshua Tay, Saumyaa Saumyaa, David Mundy, and John B. Sunwoo. "Plasticity and Polarization of Human NK Cells in the Tumor Microenvironment." Journal of Immunology 204, no. 1_Supplement (May 1, 2020): 243.24. http://dx.doi.org/10.4049/jimmunol.204.supp.243.24.
Full textHazenberg, Mette D., and Hergen Spits. "Human innate lymphoid cells." Blood 124, no. 5 (July 31, 2014): 700–709. http://dx.doi.org/10.1182/blood-2013-11-427781.
Full textGomez-Rodriguez, Julio Washington, Francoise Meylan, Robin Handon, Erika Hayes, Stacie Anderson, Martha Kirby, Richard M. Siegel, and Pamela L. Schwartzberg. "An essential role for Itk in Th9 differentiation via TCR-mediated induction of IL-2 and IRF4." Journal of Immunology 196, no. 1_Supplement (May 1, 2016): 133.35. http://dx.doi.org/10.4049/jimmunol.196.supp.133.35.
Full textLi, Jian, Andria Doty, and Sarah Glover. "Impaired AHR Signaling Contributes To Intestinal ILC3/ILC1 Conversion In The Inflamed Terminal Ileum Of Crohn’s Disease Patients." Journal of Immunology 198, no. 1_Supplement (May 1, 2017): 55.45. http://dx.doi.org/10.4049/jimmunol.198.supp.55.45.
Full textLi, Na, Vincent van Unen, Thomas Höllt, Allan Thompson, Jeroen van Bergen, Nicola Pezzotti, Elmar Eisemann, et al. "Mass cytometry reveals innate lymphoid cell differentiation pathways in the human fetal intestine." Journal of Experimental Medicine 215, no. 5 (March 6, 2018): 1383–96. http://dx.doi.org/10.1084/jem.20171934.
Full textPuttur, Franz, Laura Denney, Lisa G. Gregory, Juho Vuononvirta, Robert Oliver, Lewis J. Entwistle, Simone A. Walker, et al. "Pulmonary environmental cues drive group 2 innate lymphoid cell dynamics in mice and humans." Science Immunology 4, no. 36 (June 7, 2019): eaav7638. http://dx.doi.org/10.1126/sciimmunol.aav7638.
Full textInaba, Akihiko, Ayane Arinaga, Keisuke Tanaka, Takaho Endo, Norihito Hayatsu, Yasushi Okazaki, Takumi Yamane, Yuichi Oishi, Hiroo Imai, and Ken Iwatsuki. "Interleukin-4 Promotes Tuft Cell Differentiation and Acetylcholine Production in Intestinal Organoids of Non-Human Primate." International Journal of Molecular Sciences 22, no. 15 (July 24, 2021): 7921. http://dx.doi.org/10.3390/ijms22157921.
Full textBonne-Annee, Sandra, and Thomas B. Nutman. "Modulation of human innate lymphoid cell function by IL-10." Journal of Immunology 198, no. 1_Supplement (May 1, 2017): 208.1. http://dx.doi.org/10.4049/jimmunol.198.supp.208.1.
Full textSpits, Hergen, Jochem Bernink, Charlotte Peters, and Jenny Mjosberg. "New Insights in Development and Function of Human Innate Lymphoid Cells." Blood 120, no. 21 (November 16, 2012): SCI—19—SCI—19. http://dx.doi.org/10.1182/blood.v120.21.sci-19.sci-19.
Full textEbihara, Takashi. "Dichotomous Regulation of Acquired Immunity by Innate Lymphoid Cells." Cells 9, no. 5 (May 11, 2020): 1193. http://dx.doi.org/10.3390/cells9051193.
Full textLaky, Karen, Jessica L. Kinard, Anthony Guerrerio, Min Jenny Li, and Pamela Guerrerio. "Mutation of Tgfbr1 leads to non-hematopoietic defects that drive early onset eosinophilic inflammation in the esophagus." Journal of Immunology 202, no. 1_Supplement (May 1, 2019): 67.15. http://dx.doi.org/10.4049/jimmunol.202.supp.67.15.
Full textGao, Chunji, Xiaohong Li, Jian Ma, Xiaoxiong Wu, Feifei Wang, Meng Li, Li Yu, and Wanming Da. "Ex Vivo Expansion of Highly Purified Human NK Cells.." Blood 114, no. 22 (November 20, 2009): 2157. http://dx.doi.org/10.1182/blood.v114.22.2157.2157.
Full textBrown, J. L., L. Campbell, J. Malcolm, A. Adrados Planell, J. P. Butcher, and S. Culshaw. "Enrichment of Innate Lymphoid Cell Populations in Gingival Tissue." Journal of Dental Research 97, no. 12 (June 21, 2018): 1399–405. http://dx.doi.org/10.1177/0022034518782141.
Full textRodriguez-Nieves, Jennifer, Ryan Tuck, and Kristina De Paris. "JAK/STAT Signaling of Natural Killer (NK) Cells Following Cytokine Stimulation." Journal of Immunology 198, no. 1_Supplement (May 1, 2017): 124.20. http://dx.doi.org/10.4049/jimmunol.198.supp.124.20.
Full textPoniewierska-Baran, Agata, Beata Tokarz-Deptuła, and Wiesław Deptuła. "The role of innate lymphoid cells in selected disease states – cancer formation, metabolic disorder and inflammation." Archives of Medical Science 17, no. 1 (January 5, 2021): 196–206. http://dx.doi.org/10.5114/aoms.2019.89835.
Full textTait Wojno, Elia D., and David Artis. "Emerging concepts and future challenges in innate lymphoid cell biology." Journal of Experimental Medicine 213, no. 11 (October 10, 2016): 2229–48. http://dx.doi.org/10.1084/jem.20160525.
Full textTeunissen, M. B., L. B. Møller, MB Løvendorf, C. M. Bonefeld, L. Skov, M. Mann, and B. Dyring Andersen. "195 Proteomic Analyses of ILC2 and ILC3 from Human Skin and Peripheral Blood Reveal Distinctive Phenotypes and Functions." Journal of Investigative Dermatology 141, no. 10 (October 2021): S182. http://dx.doi.org/10.1016/j.jid.2021.08.200.
Full textAhn, Yong-Oon, Bruce R. Blazar, Jeffrey S. Miller, and Michael R. Verneris. "Human IL-22 Producing CD56+ RORγt+ Innate Lymphoid Cells and Conventional NK Cells Have Distinctive Developmental Trajectories and Are Separate Cell Lineages." Blood 120, no. 21 (November 16, 2012): 1219. http://dx.doi.org/10.1182/blood.v120.21.1219.1219.
Full textMaggi, Laura, Manuela Capone, Alessio Mazzoni, Francesco Liotta, Lorenzo Cosmi, and Francesco Annunziato. "Plasticity and regulatory mechanisms of human ILC2 functions." Immunology Letters 227 (November 2020): 109–16. http://dx.doi.org/10.1016/j.imlet.2020.08.004.
Full textZhu, Xiaoliang, and Jinfang Zhu. "CD4 T Helper Cell Subsets and Related Human Immunological Disorders." International Journal of Molecular Sciences 21, no. 21 (October 28, 2020): 8011. http://dx.doi.org/10.3390/ijms21218011.
Full textWiarda, Jayne E., Julian M. Trachsel, Sathesh K. Sivasankaran, Christopher K. Tuggle, and Crystal L. Loving. "Gene signatures for intestinal and peripheral innate lymphoid cells in pigs reveal tissue-specific imprinting and similarities to human cells via single-cell RNA sequencing." Journal of Immunology 208, no. 1_Supplement (May 1, 2022): 171.11. http://dx.doi.org/10.4049/jimmunol.208.supp.171.11.
Full textRabinowich, Hannah, Ronald B. Herberman, and Theresa L. Whiteside. "Differential Effects of IL12 and IL2 on Expression and Function of Cellular Adhesion Molecules on Purified Human Natural Killer Cells." Cellular Immunology 152, no. 2 (December 1993): 481–98. http://dx.doi.org/10.1006/cimm.1993.1306.
Full textColmenares, V., D. E. Noyola, A. Monsiváis-Urenda, M. Salgado-Bustamante, L. Estrada-Capetillo, R. González-Amaro, and L. Baranda. "Human Papillomavirus Immunization Is Associated with Increased Expression of Different Innate Immune Regulatory Receptors." Clinical and Vaccine Immunology 19, no. 7 (May 9, 2012): 1005–11. http://dx.doi.org/10.1128/cvi.00043-12.
Full textSartor, Mary M., Jenny Lau, David Gottlieb, and Kenneth F. Bradstock. "Increased Production of the Inflammatory Cytokine IL12p70 by Activated Human Blood Dendritic Cells Is Associated with Increased Severity of Acute Graft Vs Host Disease Post Allogeneic Hemopoietic Cell Transplantation." Blood 118, no. 21 (November 18, 2011): 4539. http://dx.doi.org/10.1182/blood.v118.21.4539.4539.
Full textCollins, Patrick, Marina Cella, Sofia Porter, Matthew Mccullen, Marco Colonna, and Eugene M. Oltz. "Regulatory circuits governing identity and function of human type 1 ILCs." Journal of Immunology 200, no. 1_Supplement (May 1, 2018): 170.20. http://dx.doi.org/10.4049/jimmunol.200.supp.170.20.
Full textKnipfer, Lisa, Anja Schulz-Kuhnt, Markus Kindermann, Vicky Greif, Cornelia Symowski, David Voehringer, Markus F. Neurath, Imke Atreya, and Stefan Wirtz. "A CCL1/CCR8-dependent feed-forward mechanism drives ILC2 functions in type 2–mediated inflammation." Journal of Experimental Medicine 216, no. 12 (September 19, 2019): 2763–77. http://dx.doi.org/10.1084/jem.20182111.
Full textYoussef, Youssef, Ansel P. Nalin, Jesse Kowalski, Megan Broughton, Matthew Lordo, Adam Gerhardt, Ekaterina Altynova, et al. "CD200R1 Distinguishes Uncommitted Precursors from Functionally Mature NK Cells within the Human Tonsil Stage 4A NK Cell Population." Blood 138, Supplement 1 (November 5, 2021): 993. http://dx.doi.org/10.1182/blood-2021-151783.
Full textShin, June, Nina Horowitz, Quan Tran, Chen Chen, Uriel Moreno-Nieves, Joshua Tay, Saumyaa Saumyaa, and John Sunwoo. "215 Tissue-resident natural killer cells resembling intraepithelial ILC1 have potent anti-tumor activity in human head and neck cancer and represent a novel class of effector cells for immunotherapy." Journal for ImmunoTherapy of Cancer 9, Suppl 2 (November 2021): A228. http://dx.doi.org/10.1136/jitc-2021-sitc2021.215.
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