Academic literature on the topic 'Human Centered Design methodology'

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Journal articles on the topic "Human Centered Design methodology"

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Bowman, Matthew L., Gina A. Taylor, Deana McDonagh, Leanne T. Labriola, and Dipanjan Pan. "Medical Device Design: Applying a Human-Centered Design Methodology." Proceedings of the International Symposium on Human Factors and Ergonomics in Health Care 6, no. 1 (May 15, 2017): 177–80. http://dx.doi.org/10.1177/2327857917061037.

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The OcuCheck is a novel ocular device that will disrupt the healthcare industry by reducing the need for Slit Lamps when evaluating corneal integrity. Ocular leaks should be detected and repaired quickly for the best vision outcomes. Patient comfort, user needs, and usability informed the design of the device. Key design objectives included ease of use by persons with all levels of skill, portability, and the ability to assess the patient regardless of the patient’s position or level of consciousness. We utilized a human-centric design approach, driven by the needs of both the patient and medical professionals, to elicit visual cues, patterns of behavior, and product design opportunities. We incorporated sociology, ergonomics, sustainability, human factors, business models, and marketing into the development process early on and worked in parallel with the engineers to integrate the needs of the user from the very beginning. Design, research, and prototype testing were focused upon use of materials, patient needs, ease of use, scale, location of device when not in use, and product protocols. Rather than simply creating a utilitarian solution we strove to pre-empt usability and implementation challenges through use of empathy.
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Nguyen, Hien Ngoc, Ganix Lasa, Ion Iriarte, Ariane Atxa, Gorka Unamuno, and Gurutz Galfarsoro. "Human-centered design for advanced services: A multidimensional design methodology." Advanced Engineering Informatics 53 (August 2022): 101720. http://dx.doi.org/10.1016/j.aei.2022.101720.

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Watson, Michael E., Christina F. Rusnock, John M. Colombi, and Michael E. Miller. "Human-Centered Design Using System Modeling Language." Journal of Cognitive Engineering and Decision Making 11, no. 3 (April 13, 2017): 252–69. http://dx.doi.org/10.1177/1555343417705255.

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The human user is important to consider during system design. However, common system design models, such as the system modeling language, typically represent human users and operators as external actors, rather than as internal to the system. This research presents a method for integrating human considerations into system models through human-centered design. A specific system is selected to serve as the case study for demonstrating the methodology. The sample system is analyzed to identify the task and information flow. Then, both system- and human-centered diagrams are separately created to represent different viewpoints of the system. These diagrams are compared and analyzed, and new diagrams are created that incorporate both system and human considerations into one concordant representation of the system model. These new views allow systems engineers and human factors engineers to effectively communicate the role of the user during early system design trades.
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Mitchell, Christine M. "Operations Automation: A Concept and Design Methodology for Human-Centered Automation." Proceedings of the Human Factors and Ergonomics Society Annual Meeting 47, no. 3 (October 2003): 320–24. http://dx.doi.org/10.1177/154193120304700315.

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Gaspar, José F., Ângelo P. Teixeira, Adriano Santos, C. Guedes Soares, Pavel Golyshev, and Nina Kähler. "Human centered design methodology: Case study of a ship-mooring winch." International Journal of Industrial Ergonomics 74 (November 2019): 102861. http://dx.doi.org/10.1016/j.ergon.2019.102861.

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Still, Jeremiah D., Ashley Cain, and David Schuster. "Human-centered authentication guidelines." Information & Computer Security 25, no. 4 (October 9, 2017): 437–53. http://dx.doi.org/10.1108/ics-04-2016-0034.

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Purpose Despite the widespread use of authentication schemes and the rapid emergence of novel authentication schemes, a general set of domain-specific guidelines has not yet been developed. This paper aims to present and explain a list of human-centered guidelines for developing usable authentication schemes. Design/methodology/approach The guidelines stem from research findings within the fields of psychology, human–computer interaction and information/computer science. Findings Instead of viewing users as the inevitable weak point in the authentication process, this study proposes that authentication interfaces be designed to take advantage of users’ natural abilities. This approach requires that one understands how interactions with authentication interfaces can be improved and what human capabilities can be exploited. A list of six guidelines that designers ought to consider when developing a new usable authentication scheme has been presented. Research limitations/implications This consolidated list of usable authentication guidelines provides system developers with immediate access to common design issues impacting usability. These guidelines ought to assist designers in producing more secure products in fewer costly development cycles. Originality/value Cybersecurity research and development has mainly focused on technical solutions to increase security. However, the greatest weakness of many systems is the user. It is argued that authentication schemes with poor usability are inherently insecure, as users will inadvertently weaken the security in their efforts to use the system. The study proposes that designers need to consider the human factors that impact end-user behavior. Development from this perspective will address the greatest weakness in most security systems by increasing end-user compliance.
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Vignoli, Matteo, Sara Roversi, Chhavi Jatwani, and Margherita Tiriduzzi. "HUMAN AND PLANET CENTERED APPROACH: PROSPERITY THINKING IN ACTION." Proceedings of the Design Society 1 (July 27, 2021): 1797–806. http://dx.doi.org/10.1017/pds.2021.441.

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AbstractThis work aims to test Prosperity Thinking methodology in Action and assess whether this method would respond to the needs of designers, innovators, and change-makers that are willing to change the food system. Starting from the evolution of marketing design to human-centered design, we illustrate the importance of taking into account the planet's means in the design for Sustainability at the system level. We approached the problem starting from practice, with an Action Research Innovation Management Framework (Guertler, Kriz, and Sick, 2020). Results show that designers, innovators, and changemakers have an interest in a methodology that helps them to analyze and solve systemic challenges linking the micro (human) and macro (planet) through a participatory approach to achieve long-term impact of the designed solutions.
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Barone, Eleonora. "Towards a sustainable longevity society: Instrumentalizing intergenerationality and human-centered design." ESIC MARKET Economic and Business Journal, Volume 52, Issue 2 (January 15, 2021): 401–26. http://dx.doi.org/10.7200/esicm.169.0522.3.

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Objective: This article aims to decode the opportunities of longevity societies. Methodology: It uses a qualitative analytical methodology that is nourished by the learning of 6 years of research and projects carried out in mYmO1 (entity dedicated to intergenerational innovation). It also relies on technical knowledge and analysis original sources based on the Intergenerational approach and the Human-Centered Design. The proposal presents a clear goal that is to achieve Sustainable Cities and Communities, considering the unit of space-time measurement key to start mapping projects for long-lived societies. The Sustainable Development Goals (SDGs) drawn up by the United Nations are mentioned as a reference for the scope of actions in the text, the target being SDG-11. In addition, all proposed actions are based on a premise that is taken as a basis and that lies in the importance of all actors assuming their responsibility in solving problems. In order to decode the opportunities that longevity societies offer and to achieve sustainable cities and communities, community ownership of change is considered essential. Results: Based on these considerations, a strategic matrix is designed that uses the Theory of Change to establish the relationships between actions and objectives. Desired changes are identified and what should happen to ensure that these changes lead to long-term results is analysed too. In addition, as a consequence of its practical implication, the proposed matrix is useful for small and large interventions, in any development and innovation project. Within this framework, intergenerational approach and human-centered design offer the methodology and tools to put into practice the development of concrete processes and projects. Limitations: It is an essay that shows some initiatives in concrete realities whose results are not universally extrapolated. Practical implications: As a result, new models of participation are made visible in which organizations, public authorities and individuals collaborate to solve current challenges.
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Francés Morcillo, Leire, Paz Morer-Camo, María Isabel Rodriguez Ferradas, and Aitor Cazón Martín. "The Wearable Co-Design Domino: A User-Centered Methodology to Co-Design and Co-Evaluate Wearables." Sensors 20, no. 10 (May 21, 2020): 2934. http://dx.doi.org/10.3390/s20102934.

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This paper presents a user-centered methodology to co-design and co-evaluate wearables that has been developed following a research-through design methodology. It has been based on the principles of human–computer interaction and on an empirical case entitled “Design and Development of a Low-Cost Wearable Glove to Track Forces Exerted by Workers in Car Assembly Lines” published in Sensors. Insights from both studies have been used to develop the wearable co-design domino presented in this study. The methodology consists of different design stages composed of an ideation stage, digital service development and test stages, hardware development and test stage, and a final test stage. The main conclusions state that it is necessary to maintain a close relationship between human factors and technical factors when designing wearable. Additionally, through the several studies, it has been concluded that there is need of different field experts that should co-design and co-evaluate wearable iteratively and involving users from the beginning of the process.
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Thamrin, Diana, Laksmi Kusuma Wardani, and Ronald Hasudungan Irianto Sitindjak. "Empowering Surabaya Creative Communities and Start-Ups through Human-Centered Design." GATR Global Journal of Business and Social Science Review (GJBSSR) Vol.8(2) Apr-Jun 2020 8, no. 2 (June 7, 2020): 102–12. http://dx.doi.org/10.35609/gjbssr.2020.8.2(4).

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Objective - Creative communities have the potential to increase a city’s social, economic, and touristic values. Despite their evident existence in Surabaya, these communities lack support in terms of public spaces and exhibition facilities with suitable designs that could accommodate their unique activities and communicate their aspirations to the public. This research-design project aims to prove the social and economic benefits of the human-centered design process by implementing various human-centered design approaches in the interior design of creative community spaces (CCS) so that they can accommodate the unique activities of existing creative communities and serve as assembly points for entrepreneurial or start-up groups. Methodology/Technique – Two teams of interior designers were tasked to design a community space and exhibition facility for two creative communities in Surabaya. A combined method based on different human-centered design approaches of applied ethnography, participatory design, co-design, contextual design, emphatic design, and lead user approach was conducted through six stages of design process consisting of: Empathize, Point of View, Define, Ideate, Prototype, and Test. Findings & Novelty - The results of this research-design project are novel designs of community co-working spaces and exhibition facilities based on the unique human values, hobbies, and characteristics of the creative community that proved the social and economic benefits of human-centered design in the practice of interior design. Through the design of the creative community spaces yielded, interior and building designers can promote the activities and aspirations of existing creative communities such that they may, in turn, contribute to the development of Surabaya’s social, economic, and touristic values. Type of Paper: Review JEL Classification: M13, M19. Keywords: Human-Centered Design; Creative Community; Community Design; Surabaya; Creative Economy; Design. Reference to this paper should be made as follows: Thamrin, D; Wardani, L.K; Sitindjak, R.H.I. 2020. Empowering Surabaya Creative Communities and Start-ups through Human-centred Design, Global J. Bus. Soc. Sci. Review 8(2): 102 – 112. https://doi.org/10.35609/gjbssr.2020.8.2(4)
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Dissertations / Theses on the topic "Human Centered Design methodology"

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Youssef, Omar. "Development of a Human-centered Climatic Design Methodology for Transitional Spaces in Hot-arid Regions." Thesis, The University of Arizona, 2018. http://pqdtopen.proquest.com/#viewpdf?dispub=10792744.

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The anthropogenic influences on our climate system has caused an unprecedented increase of carbon emissions amongst other greenhouse gases into our atmosphere resulting in energy imbalances and observed positive feedbacks. The American Southwest is witnessing major urban transformation as its cities are becoming centers for urban growth. Without adopting climatic design, this continued sprawl will greatly compromise the natural environment and, human health and wellbeing. Intensive urbanization has the greatest risk for increasing the carbon footprint, environmental pollution, urban heat island phenomenon, and infrastructure overextension. Increasing ground surface temperatures; the outdoor environment is observing record breaking temperature highs, while the artificial indoor set points stay the same to counter that effect.

Buildings placed in areas of excessive heat and glaring sun are in need of a comprehensive approach to address their environments. With the advancements in technology, trends have shown that architects and designers are shifting towards engineering solutions to artificially control their environments to a static state. While spaces steer away from passive designs, their operation demand high energy consumption and their occupants are deprived of a sense of nature.

Climatic design is a key ingredient to the success of an optimized environment, or to its failure. Human Health is one component that is most challenged and could be most responsive to that environment and its built parameters. The important role that these components play are greater when immersed in hot-arid regions where resources are scarce, and the built environment finds itself in a hostile environment where it struggles to survive, relying heavily on the consumption of fossil fuels.

The goal of this research is to develop a methodology in which the human physiological responses are centered in the role of design. Through examination of this phenomenon and recommendations based on the findings, developers will be informed of the importance of human-centered climatic design. Data driven to optimize both human health and the environmental footprint. Utilization of this method will not only decrease the contribution of the built environment but will also decrease the chronic exposure of humans to these high contrasts and pave the way to cautious practices optimizing health of the environment. The long-term goal is to develop indices based on human-centered climatic design to inform our design decisions and represent a flagship to a sustainable way of living. The objective of this research is to validate the dialogue between climatic design and human physiological comfort. The hypothesis is that a specific list of elements in man-made built environment trigger responses in both the atmosphere and humans. The rationale behind this methodology is based on the role of architecture as a primary instrument that could cause imbalances in both the climate and the human body.

To accomplish our objective and test our central hypothesis the authors outlined three broad environments; (climate, architecture, and human) to further investigate the relationship centered around the human body and its multisensory experience. Results of this study will allow the identification of an articulate common solution focused on transitional spaces.

The contribution of knowledge in this research is outlined in three sequential publications. The first adopts a comprehensive approach that redefines space and the elements in three environments that have an impact on it. The second leads with the previous developed relationship (from paper 1) to develop a human physiological comfort index applicable within a broader architecture foundation, and the third utilizes this index to demonstrate techniques developed in this research to measure climatic and human attributes objectively, and non-obtrusively. At the final stage these disciplines will be overlaid to create architecture unity in a sequence of variables which this document will follow. The conclusion outlines a series of concepts that represent human-centered climatic design applications.

This dissertation graphically articulates the interactive network of dialogue between humans and space to serve as a balanced approach to architectural design. The genesis of this investigation is supported by the development of a protocol that utilizes interdisciplinary research methodology that couples theoretical and empirical based discoveries to inform the fundamentals of the built environment, standards, and operations optimizing occupant health and wellbeing in extreme environments. By combining spatial design with health parameters, architects will be able to make decisions that will reduce energy consumption, decrease the impact on climate change; ultimately protect the natural world and optimally support future life. The actions taken in response to this study will not only decrease the direct impact of large temperature differences that trigger human stress responses, but will also reduce the emission of anthropogenic greenhouse gases.

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Manganelli, Joseph Charles. "Designing complex, interactive, architectural systems with CIAS-DM| A model-based, human-centered, design & analysis methodology." Thesis, Clemson University, 2014. http://pqdtopen.proquest.com/#viewpdf?dispub=3609779.

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The built environment increasingly contributes to improving human health, well-being, and performance in measurable, predictable, and tailorable ways. Achieving high-performance environmental systems requires real-time-interactive sensing, monitoring, actuation, and communication subsystems, as well as real-time interactions of these environmental systems with their users and other internal and external systems. Developing theories, constructs, methods, and tools necessary for designing such high-performance, complex, interactive systems is an active area of research.

This dissertation focused on methods and tools for representing the cognitive and physical affordances of complex, interactive, architectural systems (CIAS). The Complex, Interactive, Architectural Systems Design Methodology (CIAS-DM) was proposed as a method and tool for helping designers uncover and document the scope of proposed CIAS. CIAS-DM was evaluated qualitatively. This project used the design of a `smart' mattress in a patient room `smart' bed/mattress/over-the-bed table ecosystem as the basis for a series of design cases. Fourteen clinicians participated as subject matter experts. Four research associates participated as raters. The results of evaluating CIAS-DM indicate that CIAS-DM is useful for scoping CIAS design challenges. The contributions of this dissertation are: 1) identifying and characterizing CIAS; 2) introducing the systems modeling language (SysML) and a cognitive work analysis (CWA) representational and analytic methods into architecture; 2) mapping constructs and methods from CWA into SysML; and 3) providing these methods and tools in an integrated package appropriate for those designing CIAS.

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Garreta, Domingo Muriel. "Human-centered learning design with technology." Doctoral thesis, Universitat Pompeu Fabra, 2018. http://hdl.handle.net/10803/667048.

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To improve and innovate education, a novel conception of the role of design in this realm is needed. Human-centered design (HCD), a problem-solving framework underpinned by the user perspective in all stages of the process, provides professional designers with a mindset and a toolbox that includes both process and methods. HCD is multidisciplinary by default and also practice-oriented, context-aware, empathetic and incremental. As such it naturally fits both the design for learning and many of educators’ everyday realities. We apply this conception in the context of technology-enhanced learning with the conceptualisation and implementation of a genuine intervention for the design of ICT-mediated learning activities. Following the Activity-Centred Analysis and Design (ACAD) model, the contributions of this dissertation 1) cover the epistemic, social and set design dimensions of a teacher training activity for educators; 2) inform the incorporation of HCD in education; and 3) provide interdisciplinary learnings for research as well as practice. These contributions have been reported in a set of papers which are compiled in this dissertation together with an introductory kappa. The kappa frames and summaries the contributions, and closes with a proposal on how HCD could contribute to empower educators as designers and facilitate the much interdisciplinary collaboration between education, technology and design.
Facilitar la millora i la innovació docent, requereix d'una nova concepció del rol del disseny aplicat en l'educació. El disseny centrat en les persones (DCU) és una aproximació a la resolució de problemes que inclou la perspectiva dels usuaris en totes les etapes del procés i ofereix als dissenyadors professionals un model mental i els intruments necessaris per aplicar aquest procés i els seus mètodes. El DCU és multidisciplinar per defecte, està orientat a la pràctica, pren consciència del context d’ús, i és empàtic i incremental. Així doncs encaixa de forma natural en el disseny de l’aprenentatge i en la realitat diària del professorat. L'objectiu és aplicar aquesta concepció al disseny de l’aprenentatge mediat per la tecnologia conceptualitzant i implementant una intervenció genuïna per al disseny d’activitats d’aprenentatge que usin les TIC. Seguint el model d’Anàlisi i Disseny Centrat en l’Activitat (ACAD, en anglès), les contribucions d’aquesta dissertació 1) cobreixen les dimensions epistèmica, social i d’eines per al disseny d’una activitat de formació del professorat, 2) informen sobre la incorporació del DCU en educació; i 3) aporten aprenentatges rellevants tant per la recerca com per la pràctica de diferents disciplines. Aquestes contribucions han estat reportades en un conjunt d’articles compilats després de la kappa introductòria. La kappa emmarca i resumeix les contribucions i finalitza amb una proposta sobre com el DCU podria contribuir a apoderar els educadors en tant que dissenyadores i facilitar, d'aquesta manera, la tant necessària col·laboració interdisciplànaria entre educació, tecnologia i disseny.
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Sung, Ja-Young. "Towards the human-centered design of everyday robots." Diss., Georgia Institute of Technology, 2011. http://hdl.handle.net/1853/39539.

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The recent advancement of robotic technology brings robots closer to assisting us in our everyday spaces, providing support for healthcare, cleaning, entertaining and other tasks. In this dissertation, I refer to these robots as everyday robots. Scholars argue that the key to successful human acceptance lies in the design of robots that have the ability to blend into everyday activities. A challenge remains; robots are an autonomous technology that triggers multi-faceted interactions: physical, intellectual, social and emotional, making their presence visible and even obtrusive. These challenges need more than technological advances to be resolved; more human-centered approaches are required in the design. However to date, little is known about how to support that human-centered design of everyday robots. In this thesis, I address this gap by introducing an initial set of design guidelines for everyday robots. These guidelines are based on four empirical studies undertaken to identify how people live with robots in the home. These studies mine insights about what interaction attributes of everyday robots elicit positive or negative user responses. The guidelines were deployed in the development of one type of everyday robot: a senior-care robot called HomeMate. It shows that the guidelines become useful during the early development process by helping designers and robot engineers to focus on how social and emotional values of end-users influence the design of the technical functions required. Overall, this thesis addresses a question how we can support the design of everyday robots to become more accepted by users. I respond to this question by proposing a set of design guidelines that account for lived experiences of robots in the home, which ultimately can improve the adoption and use of everyday robots.
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Muljono, Darwin. "The Relevance of Emergence in Human-centered Design." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1468927430.

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Lugli, Daniele Moraes. "Human-centered education : uma proposta para educação em design." reponame:Repositório Institucional da UFPR, 2016. http://hdl.handle.net/1884/45696.

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Orientador: Prof. Dr. Adriano Heemann
Dissertação (mestrado) - Universidade Federal do Paraná, Setor de Artes, Comunicação e Design, Programa de Pós-Graduação em Design. Defesa: Curitiba, 29/09/2016
Inclui referências : f. 115-120
Resumo: O presente estudo investiga a integração das abordagens human-centered design e student-centered learning no contexto de um curso superior em Design. Partindo da compreensão da educação como experiência, discute-se o papel de docentes, discentes e demais stakeholders no processo, bem como possibilidades de aplicação de ferramentas inovadoras do design e da educação para o desenvolvimento de estratégias pedagógicas compatíveis com tal concepção. A fim de verificar a aplicabilidade da proposta, realizou-se uma pesquisa-ação que resultou na cocriação da estrutura de uma unidade curricular, com a participação de diversos stakeholders. Posteriormente, uma pesquisa participante descreve o desenvolvimento das aulas dessa unidade curricular ao longo de um semestre. Por meio de dados quantitativos e qualitativos, os resultados apresentam a percepção dos stakeholders em comparação à experiência dos anos anteriores. Na análise desse feedback, percebem-se aspectos positivos derivados da abordagem human- centered, mas também empecilhos na implementação relativos aos fatores humanos intrínsecos a ela. A participação dos stakeholders resultou em insights que não seriam alcançados apenas pela pesquisadora, e a possibilidade de iteração prevista no método permitiu o desenvolvimento flexível de aulas voltadas às necessidades dos estudantes, mapeadas semana a semana. O processo, como um todo, apontou a importância da colaboração entre a equipe educacional e as dificuldades percebidas quando esta não ocorre de fato. O estudo pode servir como guia para instituições que desejem implementar modelos pedagógicos mais humanizados, pois considera-se o método aplicável a outras unidades curriculares e até mesmo a outros cursos, devido à sua adaptação às necessidades contextuais. Palavras-chave: Human-centered design. Student-centered learning. Educação em design. Competências. Colaboração.
Abstract: This study investigates the integration of the human-centered design and student- centered learning approaches in the context of an undergraduate Design program. From the understanding of education as an experience, the role of professors, students and other stakeholders involved in the process is discussed, as well as the possibilities of using innovative tools from design and education fields to develop teaching strategies that are consistent with this concept. In order to verify the applicability of this proposal, an action research was conducted and resulted in the cocreation of the structure of a course unit with the participation of various stakeholders. Subsequently, a participant research describes the development of the classes over a semester. Through quantitative and qualitative data, the results showed the perception of stakeholders in comparison to the experience of previous years. After analyzing this feedback, positive aspects derived from the human-centered approach are perceived as well as obstacles to its implementation related to the human factors that are intrinsic to it. The participation of different stakeholders resulted in insights that would not be achieved by the researcher alone, and the possibility of iteration, as provided in the method, allowed the flexible development classes geared to the weekly mapped needs of students. The process as a whole highlighted the importance of collaboration in an educational team and the difficulties perceived when it does not occur in fact. The research can work as a guide for institutions wishing to implement more humane pedagogical models, since the method is applicable to other courses and even other programs due to its adaptation to contextual needs. Keywords: Human-centered design. Student-centered learning. Design education. Competencies. Collaboration.
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Baldev, Darshan H. "Design of a Construction Safety Training System using Contextual Design Methodology." Thesis, Virginia Tech, 2006. http://hdl.handle.net/10919/35200.

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In the U.S., the majority of construction companies are small companies with 10 or fewer employees (BLS, 2004). The fatality rate in the construction industry is high, indicating a need for implementing safety training to a greater extent. This research addresses two main goals: to make recommendations and design a safety training system for small construction companies, and to use Contextual Design to design the training system. Contextual Design was developed by Holtzblatt (Beyer and Holtzblatt, 1998) in an effort to address the challenge of designing new systems. Ethnographic in nature, the Contextual Design methodology requires field data collection, requirements analysis, model building, visioning and story boarding, and prototyping. A sample of 12 participants consisting of 7 tradespersons, 3 forepersons, and 2 owners/ managers, was selected for data collection. The data was analyzed based on the Contextual Design approach and a training system prototype was designed. The results of this study are recommendations for safety in small construction companies, a low fidelity paper prototype of the training system, and recommendations on future use of Contextual Design for developing training systems.
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Webert, Nina, and Marcelle Ghaoui. "En studie av Toyotas miljöarbete genom Human-Centered Design." Thesis, Mälardalens högskola, Akademin för innovation, design och teknik, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-13103.

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Det ligger något motsägelsefullt i att bilföretag arbetar med miljöfrågor. Ökad globalisering och urbanisering har haft en stor inverkan på vår miljö. Som en av världens största biltillverkare anser Toyota att de har ett stort ansvar för sitt ekologiska fotavtryck och satsar dagligen 49 miljoner kronor på miljöarbete. Examensarbetet gäller för Toyota Sweden AB med syftet att skapa nya möjligheter för att kommunicera Toyotas miljöarbete hos återförsäljarna. För att kunna uppfylla syftet arbetade vi med att besvara två övergripande forskningsfrågor: Hur ser Toyotas miljöarbete ut idag samt  Hur kan Toyotas miljöprofil förstärkas hos återförsäljarna? Då forskningsfrågorna var av bred karaktär valde vi att arbeta efter IDEO:s framtagna process Human-Centered Design, kombinerat med det arbetssätt som Anders Wikström utvecklat genom den forskning han bedriver vid Mälardalens högskola. Vid Human-Centered Design utgår man från de människor man designar för genom att utveckla empati, dvs. en djup förståelse för de problem och den verklighet de människorna lever i.  Resultatet av examensarbetet kom att bestå av två delar. Dels en nulägesanalys av Toyotas miljöarbete och hur det återspeglas hos återförsäljarna. Dels ett visionärt koncept, Talking Cars, som skildrar ett framtida sätt att köpa bil som syftar till att förstärka upplevelsen i bilhallen.  En av många slutsatser som kan dras av examensarbetet är att Toyota gör det de säger sig göra i samband med sitt miljöarbete. De behöver dock bli tydligare i sin kommunikation till omvärlden för att kunna göra sitt miljöarbete rättvisa. Genom detta examensarbete är våra förhoppningar att Toyota har fått insikter och inspiration till hur de skulle kunna gå tillväga.
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Liu, Jenny S. B. Massachusetts Institute of Technology. "Inclusive : a human centered approach to accessible architectural design." Thesis, Massachusetts Institute of Technology, 2018. http://hdl.handle.net/1721.1/118700.

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Thesis: S.B., Massachusetts Institute of Technology, Department of Architecture, 2018.
Cataloged from PDF version of thesis.
Includes bibliographical references (pages 72-74).
Architecture is about creating spaces for people to live their best lives, yet architecture can be disconnected from the people most directly impacted by its work. According to a survey in 2015, only 2.6% of non-architects feel that the profession does an excellent job of understanding the needs and desires of those living and working in our buildings. As such, occupants suffer spaces that are uncomfortable and sometimes unusable; in particular, people with disabilities are often restricted to certain spaces because most places are designed without any consideration of their needs.. Universal design, a new concept in architecture, asks how can we design in a way that makes life easier, healthier, and friendlier for all by putting people with disabilities on an equal playing field with other types of users. Universal design draws from accessibility standards and design principles to create environments that can be used by as many as possible without specialized design accommodations. Integrating accessibility and universal design principles in architecture could enrich our understanding of a space and add a new layer of spatial experience for everyone. The purpose of this thesis is to investigate what makes spaces inclusive and usable for those with disabilities, how we can design for a broader population, and whether we should embrace universal design ideas. This thesis will use a review of the history and current practices of universal and accessible design and precedent studies to inform a design process focused on understanding the users and their experiences in order to maximize usability. Then, this thesis will apply this knowledge by assessing the MIT Stratton Student Center and the Ray and Maria Stata Center using observations and surveys to find the gap between their designs and universal design principles. This analysis will provide findings and recommendations of how universal design can be better incorporated in public spaces on MIT's campus.
by Jenny Liu.
S.B.
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Wallace, Michael D. "METIS : a human-computer interface design methodology." Thesis, University of Ulster, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261053.

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Books on the topic "Human Centered Design methodology"

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Kurosu, Masaaki, ed. Human Centered Design. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-21753-1.

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Kurosu, Masaaki, ed. Human Centered Design. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-02806-9.

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Boy, Guy André. Orchestrating Human-Centered Design. London: Springer London, 2013. http://dx.doi.org/10.1007/978-1-4471-4339-0.

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Boy, Guy André. Orchestrating Human-Centered Design. London: Springer London, 2013.

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Human factors methods for design: Making systems human-centered. New York, NY: Taylor & Francis, 2004.

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Scataglini, Sofia, Silvia Imbesi, and Gonçalo Marques, eds. Internet of Things for Human-Centered Design. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-8488-3.

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Human-centered system design for electronic governance. Hershey, PA: Information Science Reference, 2013.

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Pfannstiel, Mario A., ed. Human-Centered Service Design for Healthcare Transformation. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-20168-4.

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Rouse, William B. People and organizations: Explorations of human-centered design. Hoboken, N.J: John Wiley, 2007.

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Feng, Dong, Ghinea Gheorghita, and Chen Sherry Y, eds. User centered design for medical visualization. Hershey: Medical Information Science Reference, 2008.

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Book chapters on the topic "Human Centered Design methodology"

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Garcia, Camila Kamarad Zocal. "Human-Centered Product Owner: How Human-Centered Design Can Sharpen Scrum Methodology." In Communications in Computer and Information Science, 409–13. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-21380-4_69.

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Imbesi, Silvia. "Human-Centered Design for Older Users: A Design Methodology for the Development of Smart Devices and Systems Related to Health Care." In Internet of Things for Human-Centered Design, 25–37. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-8488-3_2.

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Fischer, Holger, Michael Engler, and Stefan Sauer. "A Human-Centered Perspective on Software Quality: Acceptance Criteria for Work 4.0." In Design, User Experience, and Usability: Theory, Methodology, and Management, 570–83. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-58634-2_42.

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Seymoens, Tom, Femke Ongenae, An Jacobs, Stijn Verstichel, and Ann Ackaert. "A Methodology to Involve Domain Experts and Machine Learning Techniques in the Design of Human-Centered Algorithms." In Human Work Interaction Design. Designing Engaging Automation, 200–214. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-05297-3_14.

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Astudillo, Boris, Katherine Cajilema, Marco Santórum, and Jose Aguilar. "Analysis, Evaluation, and Upgrading of a Data Analytics Methodology Through a Qualitative Evaluation Technique and a User-Centered Design Process." In Human Systems Engineering and Design III, 123–28. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-58282-1_20.

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Imbesi, Silvia, Giuseppe Mincolelli, and Filippo Petrocchi. "How to Enhance Aging People’s Wellness by Means of Human Centered and Co-design Methodology." In Advances in Simulation and Digital Human Modeling, 216–25. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-51064-0_28.

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Chen, Pei, and Yaping Huang. "Evaluation Methodology on Industry-City Integration Degree of China National High-Tech Industrial Development Zones: A Case Study of Hubei Province." In Human-Centered Urban Planning and Design in China: Volume I, 163–78. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-83856-0_10.

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Park, Sunyoung, Long Xu, Sunguen Lee, and Sangwon Lee. "A Study on the Improvement of Operation Log for Kindergarten School Bus Safety Using Human-Centered Design Methodology." In Advances in Human Factors in Communication of Design, 47–59. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-93888-2_5.

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Knezevic, Bojana, Roman Andrzej Lewandowski, Anatoliy Goncharuk, and Maja Vajagic. "Studying the Impact of Human Resources on the Efficiency of Healthcare Systems and Person-Centred Care." In Intelligent Systems for Sustainable Person-Centered Healthcare, 145–64. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-79353-1_8.

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AbstractWe explore the alternative explanation for barriers and facilitators for implementation of PCC evolving from human resources through the lenses of institutional theory. We have deepened the explanation by adding the perspective of different institutional logics, which shows that the physician's resistance or nurses’ support may originate from the differences in institutional logics. Working with patients by applying person-centered principles places new demands on health professionals. It is widely agreed that education and training are very important for the clarification on the roles of professionals in the person-centred care. PCC education programs were designed to be delivered through informal training, continued medical education, leadership development and training through mentors’ system. Managers, on the other hand, may support the implementation of PCC, but their motivation may be less oriented to increase of service quality, than gaining higher external legitimacy of the organization and increase organizational access to external resources. Therefore, managers may not implement sufficient control and motivational mechanisms for healthcare professionals for following PCC routines and make them slip back into ‘usual care’ or lose interest, knowledge or commitment. As the psychological state of medical staff can determine the duration and success of the treatment and care, therefore they should be properly motivated. In this chapter we show comparative research study in Ukraine and Poland. The methodology of this study selected a list of motivators for medical staff in both countries. The results of this study brought the main findings that may be useful for reforming inefficient healthcare systems.
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Imbesi, Silvia, Mattia Corzani, Filippo Petrocchi, Giovanna Lopane, Lorenzo Chiari, and Giuseppe Mincolelli. "User-Centered Design of Cues with Smart Glasses for Gait Rehabilitation in People with Parkinson’s Disease: A Methodology for the Analysis of Human Requirements and Cues Effectiveness." In Advances in Simulation and Digital Human Modeling, 348–58. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-79763-8_42.

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Conference papers on the topic "Human Centered Design methodology"

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Guedes Alcoforadoa, Manoel, José Carlos Plácido da Silvab, and Luis Carlos Paschoarellib. "Prototype-Centered Design: For Better Interactive Design Process." In Applied Human Factors and Ergonomics Conference (2022). AHFE International, 2022. http://dx.doi.org/10.54941/ahfe1001262.

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Several authors have talked about the complexity of the design activity, pointing several factors to its elevation, such as: globalization, reduction of the development cycle and product diversification, sustainability, rapid changes in user behavior, new materials and production technologies, ... it has expanded the research in methodology and stimulated the emergence of new technologies applied to the development of projects such as: 3D scanning, rapid prototyping and rapid manufacturing technologies. In this context, after several research about methodology and design management, we find that the design process could become more interactive and efficient if the prototyping activity could assume the central role in the design process and if appropriate prototypes were used in each phase, stage and purpose of design. Those factors could improve the management, the communication inside the team and among other actors in the process and expand the insertion and evaluation of user requirements. Accordingly, this article will present the results of a doctoral research in design which proposes a new design methodology centered on the prototype and the results obtained after the completion of a projective challenge to experiment and validate that methodology.
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Lubis, Pierre Yohanes, and Bahareh Shahri. "Human-Centered Design as a Qualitative Research Methodology in the Area of Public Health." In – The European Conference on Arts, Design and Education 2022. The International Academic Forum(IAFOR), 2022. http://dx.doi.org/10.22492/issn.2758-0989.2022.8.

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Ahmed, Salman, Lukman Irshad, and H. Onan Demirel. "Computational Prototyping Methods to Design Human Centered Products of High and Low Level Human Interactions." In ASME 2019 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2019. http://dx.doi.org/10.1115/detc2019-98450.

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Abstract Incorporating human factors engineering guidelines early in design has the potential to reduce the cost and product lead-time to market. Also, products that go through strict ergonomics assessments are associated with better comfort and safety ratings. However, designers are often caught in the dilemma of what prototyping method to use when assessing product ergonomics early in design. This is especially problematic during the conceptual design phase before the physical prototypes are available or built. In this research, we explore the computational prototyping dilemma for early design ergonomics assessments from both fidelity and human-product interaction perspectives. In this paper, three computational prototypes with different fidelity levels (low, medium-, and high-fidelity) are compared in their adequacy for evaluating designs that comprise low- to high-levels of human-product interactions. We used three computational prototyping strategies: (1) Method #1 is a low-fidelity methodology based a digital sketchpad tool; (2) Method #2 is a medium-fidelity methodology consisted of computer-aided design and digital human modeling; and, (3) Method #3 is a high-fidelity methodology composed of computer-aided design, digital human modeling, and surrogate modeling. In order to perform computational ergonomics analyses using above approach, we selected a generic wall mounted cabinet design and a simplified Boeing 767 cockpit model as case studies to illustrate designs that require low- and high-levels of human-product interactions. Our preliminary results show that low-, medium- and high-level prototyping strategies produce similar ergonomics outcomes when evaluating low-level human-computer interaction (e.g., cabinet model). On the other hand, both low- and medium-fidelity (Method #1 and Method #2) prototyping strategies are limited in terms of providing detailed information about human performance when compared to high-fidelity prototyping (Method #3) in evaluating designs with high-level human-computer interaction (e.g., cockpit model).
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Moquillaza, Arturo, and Freddy Paz. "Applying a user-centered design methodology to develop usable interfaces for an Automated Teller Machine." In Interacción '17: XVIII International Conference on Human Computer Interaction. New York, NY, USA: ACM, 2017. http://dx.doi.org/10.1145/3123818.3123833.

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Jawaharlal, Mariappan, Stephanie Nguyen Ellingwood, and Kiranbala Thokchom. "Life Centered Design Using Morphological Chart." In ASME 2016 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/imece2016-65121.

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Traditional engineering design is a customer-centric approach that focuses on maximizing performance objectives and minimizing costs under resource constraints. This approach may be effective in meeting the needs of a particular customer but may be detrimental for a larger group of people. A more inclusive human-centered design attempts to deal with a broader base of customers extending beyond geographical boundaries. Inadequacy of even this approach is apparent, as only humans are the center of this design paradigm. Life Centered Design (LCD) is different from traditional design methodology. It accounts for all forms of life by creating beneficial symbiotic relationships between humans and other living matters leading to sustainability. Nature has solved most problems we face in some form, and it continues to inspire humans. In this context, the LCD approach makes perfect sense as a concept. The challenge, however, is to find solutions using the LCD approach. How do engineers, who avoided biology in the first place, identify potential solutions from nature for solving problems in hand? This paper proposes the use of morphological charts in the early design phase to generate potential solutions. Specifically, the objective is to develop a structured system that will enable industry innovators to correlate everyday engineering functions with those available in nature. By developing a morphological chart with this correlation, engineers and designers can now identify and create life-friendly designs.
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Silveira Dias, José. "Symbiosis Design: An Interdisciplinary Methodology." In 13th International Conference on Applied Human Factors and Ergonomics (AHFE 2022). AHFE International, 2022. http://dx.doi.org/10.54941/ahfe1001370.

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Thinking conceptually on what is tangible results in ideas that feed cycles of thought. This incremental continuum gives rise to a reflection on the current crisis of temporal dispersion.Creativity can be continuously stimulated through life-long learning. When exploring societal active methodologies within teaching and learning processes, Design is an interdisciplinary subject aided by: Artificial Intelligence in rethinking the positioning that humans conquered as conscious beings, but which underestimates nature and fails to recognize its dependency on other species; User-centered Psychotherapy and Spatial Interaction towards strategies for emotions and mind impulses which correspond to societal behaviors; Social Sciences in the context of Landscapes and Territorial Dynamics; Bionics and Mimetics reformulating technology through Nature as a model; Human Factors Engineering in the investigation of the cognitive system in the adequacy of physical and digital agents. It is projected consolidate the design of the procedural spiral in the design orientation of a methodology for the Design that leads the memory in anticipation to the retroactive effect of the knowledge that will operationalize responsible creative contents, aiming at the expansion of a remembrance against the forgetfulness of the human being to care Mother Earth.The intention to develop and validate this societal active methodology started from a model (4Xself) elaborated in the context of the PhD that, with the guidance of the respective Practical Assignments Guide, intends to guide a Symbiosis Proto-Methodology. This model was applied in 2019/20 and 2020/21 with students, and preliminary conclusions have already been reached in the scope of SPIRAL project. This project aligns with the 4th SDG on education, specifically target goal 4.7, as we aim to contribute to the SDGs defined by the UN in a transversal way with the methodology. We aspire to achieve acceptance of concepts and practices that integrate the research questions: How to create and implement a Symbiosis methodology that promotes interdisciplinary, sustainable, and ethically committed design processes? How can this methodology consolidate its meaning as a catalyst and aggregator system for acting in the Design process, guaranteeing the benefit of the agents involved?The expected outcomes of this project result from exploring different media channels to disseminate and implement Symbiosis’s proto-methodology whose expertise promote the crossing of knowledge in the respective areas and interactive practices in education, training in companies, in entrepreneurship and professionalization, ensuring the following principles: be transversal to the values and mission of the methodology for a more qualitative strategy in teaching; supporting a transition to information glocalization; reflect on Education as a learning channel for all; encourage a shared responsibility among everyone involved in the design process guaranteeing code of conduct; develop an operational methodology with and for society through Co-design and Participatory Design to better qualify individuals in society and this as a social collectively; improving training methodologies in education through interdisciplinarity and participatory learning; be enrolled in the ECO triangulation in which the Social, Economic and Ecological aspects are marked out between the poles Perception/Production and Nature/Culture in the domains of Design, Art, Science and Engineering
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Song, Joobong, Keun Ryang Park, Sanghyun Kwon, Ji Hwan Lee, Myung Hwan Yun, and Joohwan Lee. "The Development of Human-System Interactivity Metrics for Ubiquitous Service Applying User-Centered Design Methodology." In 2009 IEEE Congress on Services (SERVICES). IEEE, 2009. http://dx.doi.org/10.1109/services-i.2009.89.

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Serpa, Teresa, and Fernando Moreira da Silva. "User Centered Design Principles for Entrepreneurs: Quality and Sustainability Since Start-Ups Beginning." In Applied Human Factors and Ergonomics Conference. AHFE International, 2022. http://dx.doi.org/10.54941/ahfe1001322.

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This paper aims to enhance the importance of User Centered Design specifically for entrepreneurs, improving their companies and products and/or services. The focus of the research project concerns the importance of Design in service start-ups. The current situation, with the economical crisis and the consequent unemployment, created the opportunity for many individuals to develop their own companies, generating jobs for themselves and others. Usually, those entrepreneurs choose the same work industry where they have previous experience and know-how. Anyhow we have to consider that the average of startup companies end before being three years old. Before the creation, during daydreaming and the “kitchen table meetings” phase, people underestimate the time and effort needed to create, raise and maintain this kind of companies. This is a very important moment for the company’s maintenance and future. Focusing on the paradigm change, companies and entrepreneurs need to adapt themselves to the new reality through know-how. We underline the importance of User Centered Design (methodology and tools), Ergonomics and Human Factors to develop the projects in those small companies, which are fundamental to operationalize, enhance quality and increase global sustainability leading as main research result to a model where those are core aspects.
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Ahmed, Salman, and H. Onan Demirel. "A Pre-Prototyping Framework to Explore Human-Centered Prototyping Strategies During Early Design." In ASME 2020 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/detc2020-22700.

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Abstract Current prototyping frameworks are often prompt-based and heavily rely on designers’ experience. The lack of systematic guidelines in prototyping activities causes unwanted variation in the quality of the prototype. Notably, there is limited, or no prototyping framework exists that enables human factors engineering (HFE) guidelines be part of the early product development process. In this paper, a pre-prototyping framework is proposed to render human-centered design strategies to guide designers before the hands-on prototyping activity starts. The methodology consists of extracting key factors related to prototyping and human factors engineering principles based on an extensive literature review. The key elements are then combined to form the prototyping categories, dimensions (theory), and tools (practice). The resulting prototyping framework can be used to develop prototyping strategies consist of theoretical guidelines and practical tools that are needed during the prototyping of human-centered products. The framework provides systematic guidance to designers in the early stages of the design process so that designers, in particular novices in ergonomics and human factors, can have a head start in building the prototypes in the right direction. Finally, a case study is presented to demonstrate a walk-through and efficacy of the proposed pre-prototyping framework.
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Ko, Hyunwoong, Sangwon Lee, Dongmin Shin, and Seung Ki Moon. "A Formal Model of Human Interactions for Service Ecosystem Design." In ASME 2014 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/detc2014-34839.

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In this digital era, the natures of services are becoming increasingly complex and diverse due to the convergences between the existing human-centered services and other supportive device services, or interactions between heterogeneous services. Expecting this trend is to be accelerated more, new scientific and engineered approaches to the service design are needed more than ever. In this context, a service designed conceptually and abstractly has significant limitations that keep the customers’ satisfaction from advancing above a certain level. Hence, in an initial service design phase, a service delivery process can be expressed quantitatively through a systematic analysis of its natures and the goals. In this paper, a human-centered complex service system is newly defined as service ecosystem. This study proposes a method for designing service processes as a Discrete Event System (DES) in formal ways by utilizing the concepts of affordance, preference, and a Affordance-based Finite State Automata (FSA) modeling methodology. The proposed design method suggests a model framework that focuses on service actions that reflects related properties of customers, employees, and environment entities and their interactions quantitatively. The formally expressed relations between properties of service entities such as customer, employee, and service environment provide guidelines for service designers in a more scientific way than traditional ones. In addition, it is expected that it will enable to add computational to the human-centered service system design and control and develop effective reusable controllers for complex service deliveries as well.
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Reports on the topic "Human Centered Design methodology"

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Scott, Ronald, Emille M. Roth, Stephen E. Deutsch, Erika Malchiodi, Thomas E. Kazmlerczak, Robert G. Eggleston, Smauel R. Kuper, and Randall D. Whitaker. Work-Centered Support Systems: A Human-Centered Approach to Intelligent System Design. Fort Belvoir, VA: Defense Technical Information Center, January 2003. http://dx.doi.org/10.21236/ada446490.

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Boyle, Edward. The Poet Revealed: A Future for Human-Centered Design. Fort Belvoir, VA: Defense Technical Information Center, September 1990. http://dx.doi.org/10.21236/ada226648.

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Iribagiza, Chantal. Human-Centered Design of an Air Quality Feedback System to Promote Healthy Cooking. Portland State University Library, January 2000. http://dx.doi.org/10.15760/etd.6432.

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Colina Unda, Vanessa. Citizen Experience Design for Digital Transformation. Inter-American Development Bank, April 2021. http://dx.doi.org/10.18235/0003194.

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How many times have you heard the term "human-centered design"? How about "human-centered technology"? These terms are often used interchangeably in conversations involving digital transformation. The purpose of this paper is to provide a path for policymakers to start considering user-centric design to better understand citizens characteristics, challenges, and needs. The guidelines and case studies presented here are meant to be timeless, high-level, and strategic. There is a focus on principles throughout the publication that can be used and adapted for any particular starting point. The paper also describes suggested metrics to measure and improve the quality of the citizen experience.
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Furman, Susanne, Mary Theofanos, and Sam Chapman. Human Engineering Design Criteria Standards Part 2 : Methodology and Interview Results FY10-14 DHS S [and] T Standards Project. National Institute of Standards and Technology, April 2014. http://dx.doi.org/10.6028/nist.ir.7934.

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Weller, Joel I., Harris A. Lewin, and Micha Ron. Determination of Allele Frequencies for Quantitative Trait Loci in Commercial Animal Populations. United States Department of Agriculture, February 2005. http://dx.doi.org/10.32747/2005.7586473.bard.

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Individual loci affecting economic traits in dairy cattle (ETL) have been detected via linkage to genetic markers by application of the granddaughter design in the US population and the daughter design in the Israeli population. From these analyses it is not possible to determine allelic frequencies in the population at large, or whether the same alleles are segregating in different families. We proposed to answer this question by application of the "modified granddaughter design", in which granddaughters with a common maternal grandsire are both genotyped and analyzed for the economic traits. The objectives of the proposal were: 1) to fine map three segregating ETL previously detected by a daughter design analysis of the Israeli dairy cattle population; 2) to determine the effects of ETL alleles in different families relative to the population mean; 3) for each ETL, to determine the number of alleles and allele frequencies. The ETL on Bostaurusautosome (BT A) 6 chiefly affecting protein concentration was localized to a 4 cM chromosomal segment centered on the microsatellite BM143 by the daughter design. The modified granddaughter design was applied to a single family. The frequency of the allele increasing protein percent was estimated at 0.63+0.06. The hypothesis of equal allelic frequencies was rejected at p<0.05. Segregation of this ETL in the Israeli population was confirmed. The genes IBSP, SPP1, and LAP3 located adjacent to BM143 in the whole genome cattle- human comparative map were used as anchors for the human genome sequence and bovine BAC clones. Fifteen genes within 2 cM upstream of BM143 were located in the orthologous syntenic groups on HSA4q22 and HSA4p15. Only a single gene, SLIT2, was located within 2 cM downstream of BM143 in the orthologous HSA4p15 region. The order of these genes, as derived from physical mapping of BAC end sequences, was identical to the order within the orthologous syntenic groups on HSA4: FAM13A1, HERC3. CEB1, FLJ20637, PP2C-like, ABCG2, PKD2. SPP, MEP, IBSP, LAP3, EG1. KIAA1276, HCAPG, MLR1, BM143, and SLIT2. Four hundred and twenty AI bulls with genetic evaluations were genotyped for 12 SNPs identified in 10 of these genes, and for BM143. Seven SNPs displayed highly significant linkage disequilibrium effects on protein percentage (P<0.000l) with the greatest effect for SPP1. None of SNP genotypes for two sires heterozygous for the ETL, and six sires homozygous for the ETL completely corresponded to the causative mutation. The expression of SPP 1 and ABCG2 in the mammary gland corresponded to the lactation curve, as determined by microarray and QPCR assays, but not in the liver. Anti-sense SPP1 transgenic mice displayed abnormal mammary gland differentiation and milk secretion. Thus SPP 1 is a prime candidate gene for this ETL. We confirmed that DGAT1 is the ETL segregating on BTA 14 that chiefly effects fat concentration, and that the polymorphism is due to a missense mutation in an exon. Four hundred Israeli Holstein bulls were genotyped for this polymorphism, and the change in allelic frequency over the last 20 years was monitored.
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Evidence-informed planning and action in Central Asia: Learnings from the Tajikistan Adolescent Wellbeing and Health Pilot Project. Population Council, 2021. http://dx.doi.org/10.31899/sbsr2021.1046.

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To address adolescent health and wellbeing in Tajikistan, the Aga Khan Foundation (AKF) and Population Council used a hybrid human-centered (HCD) and evidence-based program design to engage adolescent girls, boys, and caregivers in a guided process of defining key issues and program areas. The design informed the development of a first-of-its-kind program model for AKF and in Tajikistan: coordinated community-based groups for adolescent girls and boys, caregivers' groups, and an institutional stakeholder community of practice in Tajikistan. Design and implementation experiences established "proof of concept" as a basis to expand the approach across the country and region. The pilot generated valuable lessons and resources to inform and support both expansion and new programming.
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