Relevant bibliographies by topics / Human Biophysics

Academic literature on the topic 'Human Biophysics'

Author: Grafiati
Published: 4 June 2021
Last updated: 31 January 2023

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Journal articles on the topic "Human Biophysics"

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Kalashnikov, Nikita, and Christopher Moraes. "Engineering physical microenvironments to study innate immune cell biophysics." APL Bioengineering 6, no. 3 (September 1, 2022): 031504. http://dx.doi.org/10.1063/5.0098578.

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Innate immunity forms the core of the human body's defense system against infection, injury, and foreign objects. It aims to maintain homeostasis by promoting inflammation and then initiating tissue repair, but it can also lead to disease when dysregulated. Although innate immune cells respond to their physical microenvironment and carry out intrinsically mechanical actions such as migration and phagocytosis, we still do not have a complete biophysical description of innate immunity. Here, we review how engineering tools can be used to study innate immune cell biophysics. We first provide an overview of innate immunity from a biophysical perspective, review the biophysical factors that affect the innate immune system, and then explore innate immune cell biophysics in the context of migration, phagocytosis, and phenotype polarization. Throughout the review, we highlight how physical microenvironments can be designed to probe the innate immune system, discuss how biophysical insight gained from these studies can be used to generate a more comprehensive description of innate immunity, and briefly comment on how this insight could be used to develop mechanical immune biomarkers and immunomodulatory therapies.
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Stiers, Kyle M. "Personalized biophysics of human PGM1 deficiency." Acta Crystallographica Section A Foundations and Advances 73, a1 (May 26, 2017): a167. http://dx.doi.org/10.1107/s0108767317098348.

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Yanaka, Saeko, Takamasa Ueno, Kouhei Tsumoto, and Kenji Sugase. "Revealing the peptide presenting process of human leukocyte antigen through the analysis of fluctuation." BIOPHYSICS 11 (2015): 103–6. http://dx.doi.org/10.2142/biophysics.11.103.

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Connelly, Patrick R. "Recent drug discovery success signals renaissance in biophysics." Biophysics Reviews 3, no. 2 (June 2022): 020401. http://dx.doi.org/10.1063/5.0099305.

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With a scope that spans the hierarchy of biological organization from molecules and cells to organisms and populations, the discipline of biophysics has been proven to be particularly well suited for connecting the molecular embodiments of human diseases to the medical conditions experienced by patients. Recently, fundamental biophysical research on aberrant proteins involved in maintaining salt and water balance in our lungs, oxygen transport from our lungs to the rest of the body, and the pumping of blood by our hearts have been successfully translated to the creation of transformational new medicines that are radically changing the lives of patients. With these and other emerging discoveries, the field of applied biophysics is experiencing the beginnings of a veritable renaissance era.
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Vincze, Janos, Gabriella Vincze-Tiszay, and Julianna Szakacs. "The Biophysical Modeling of the Hemodynamic in the Human Organism." Advances in Social Sciences Research Journal 7, no. 11 (December 8, 2020): 494–502. http://dx.doi.org/10.14738/assrj.711.9420.

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The circulatory apparatus has as a main function the constant maintaining of the internal environment in all the regions of the organism. The blood is a liquid tissue, being formed of a fundamental substance – plasma and blood cells. Heart is the central organ of the cardiovascular apparatus. The heart muscles have numerous biophysical properties. The cardiac muscle is never tired unless it suffered a pathological process. During the diastole, blood is aspired in the heart and during the systole it is pushed in the big and small circulation. The blood amount pushed from the heart in the vascular system in a certain time represents the blood flow. The biophysical methods are next: we administer a certain substance amount, then its passing speed will depend on its concentration; to apply the calorimetric principles for the measurement of the gastric blood flow; the diagnostic of a chronic peripheral arteriopathy we use the calorimetric method is based on measuring the heat being introduced in a certain amount of water which has known temperature; one of the most often used methods for the evaluation of the use of radioisotopes in the cardio-vascular system is the compartment method. Any attempt to apply biophysics to the life systems involves three stages. First we observe the phenomena and formulate a biophysical description in the form of equations; after to solve the equations. Finally we return to the real life system and interpret this solution in terms of reality, this interpretation may requiew experimental testing.
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Sprinzak, David, and Stephen C. Blacklow. "Biophysics of Notch Signaling." Annual Review of Biophysics 50, no. 1 (May 6, 2021): 157–89. http://dx.doi.org/10.1146/annurev-biophys-101920-082204.

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Notch signaling is a conserved system of communication between adjacent cells, influencing numerous cell fate decisions in the development of multicellular organisms. Aberrant signaling is also implicated in many human pathologies. At its core, Notch has a mechanotransduction module that decodes receptor–ligand engagement at the cell surface under force to permit proteolytic cleavage of the receptor, leading to the release of the Notch intracellular domain (NICD). NICD enters the nucleus and acts as a transcriptional effector to regulate expression of Notch-responsive genes. In this article, we review and integrate current understanding of the detailed molecular basis for Notch signal transduction, highlighting quantitative, structural, and dynamic features of this developmentally central signaling mechanism. We discuss the implications of this mechanistic understanding for the functionality of the signaling pathway in different molecular and cellular contexts.
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Summers, RL. "Physiology and Biophysics of the 100-m Sprint." Physiology 12, no. 3 (June 1, 1997): 131–36. http://dx.doi.org/10.1152/physiologyonline.1997.12.3.131.

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The 100-m sprint is the most exciting of Olympic events, and the winner is often called the "world's fastest human." The physiology of this race is unique and invovles our most primordial survival mechanisms. A computer stimulation predicts the theoretical "physiological" limits for human achievement in this event.
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Lee, Keel Yong, Sung-Jin Park, David G. Matthews, Sean L. Kim, Carlos Antonio Marquez, John F. Zimmerman, Herdeline Ann M. Ardoña, Andre G. Kleber, George V. Lauder, and Kevin Kit Parker. "An autonomously swimming biohybrid fish designed with human cardiac biophysics." Science 375, no. 6581 (February 11, 2022): 639–47. http://dx.doi.org/10.1126/science.abh0474.

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Biohybrid systems have been developed to better understand the design principles and coordination mechanisms of biological systems. We consider whether two functional regulatory features of the heart—mechanoelectrical signaling and automaticity—could be transferred to a synthetic analog of another fluid transport system: a swimming fish. By leveraging cardiac mechanoelectrical signaling, we recreated reciprocal contraction and relaxation in a muscular bilayer construct where each contraction occurs automatically as a response to the stretching of an antagonistic muscle pair. Further, to entrain this closed-loop actuation cycle, we engineered an electrically autonomous pacing node, which enhanced spontaneous contraction. The biohybrid fish equipped with intrinsic control strategies demonstrated self-sustained body–caudal fin swimming, highlighting the role of feedback mechanisms in muscular pumps such as the heart and muscles.
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Kuo, A. D. "BIOPHYSICS: Harvesting Energy by Improving the Economy of Human Walking." Science 309, no. 5741 (September 9, 2005): 1686–87. http://dx.doi.org/10.1126/science.1118058.

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Ernest, Nola Jean, Naomi J. Logsdon, Michael B. McFerrin, Harald Sontheimer, and Susan E. Spiller. "Biophysical Properties of Human Medulloblastoma Cells." Journal of Membrane Biology 237, no. 2-3 (October 2010): 59–69. http://dx.doi.org/10.1007/s00232-010-9306-x.

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Dissertations / Theses on the topic "Human Biophysics"

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Ogilvie, Julian Andrew. "Functional specialisation in human visual processing." Thesis, Imperial College London, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.286444.

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Schluter, Nathaniel D. "Human premotor cortex : imaging and interference." Thesis, University of Oxford, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284344.

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Walker, Lloyd T. "The biomechanics of the human foot." Thesis, University of Strathclyde, 1991. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=21131.

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This thesis reports on work undertaken to study the biomechanics of the human foot during normal daily activity, particularly walking and standing. A literature review is presented on topics related to the subject and several of the areas demanding further investigation are highlighted. Three lines of enquiry were pursued to consider the kinematics, kinetics, passive structural properties and muscle activity associated with the foot. A dynamic pedobarograph with a synchronised video system was used to measure the forces and their distribution under the foot (based on seven marked areas) and six kinematic angles of the foot and lower leg. Sixty-one healthy subjects were assessed and the results are presented. Kinetic and kinematic parameters were found to be consistent and smooth for the test population. Several of the events of the gait cycle were found to be temporally different from values widely reported. In the second investigation, four cadaveric foot specimens were tested dynamically to determine the role of the plantar structures during loading in various positions. A method of sequential dissection was used and the results support many of the theories regarding ligament function. Tests on the effect of three extrinsic muscles on the foot load distribution also support previous studies while a preliminary investigation of two pathological feet partially clarifies the biomechanical effects of a hallux valgus deformity. Eight of the foot extrinsic and intrinsic muscles were assessed for the final investigation. Using electromyographic (EMG) recording techniques on six healthy subjects, the muscle EMG activity was quantified during walking a) barefoot, b) with a moulded heel plate, and c) with soft shoes. The results for the extrinsic muscles generally agree with previous work, while the intrinsic muscle activity is more variable. The intrinsic muscles were more active when shoes were worn and displayed unusual fatigue patterns.
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Schechtman, Helio. "Mechanical characterisation of fatigue failure in human tendons." Thesis, Queen Mary, University of London, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.297451.

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Alexopoulos, Evangelos Demetrios. "Extracellular matrix associated with human luteinizing granulosa cells." Thesis, University of Southampton, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.369867.

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Scase, Mark O. "Studies on normal and impaired human colour vision." Thesis, Keele University, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.254775.

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Tha, Susan P. L. "Interaction forces between human red cells aggutinated by antibody." Thesis, McGill University, 1987. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=75421.

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A theoretical and experimental method is described whereby the hydrodynamic forces, both normal and shear, acting on the spheres of a doublet can be calculated. This is applied to a system of sphered human red blood cells agglutinated by human hyperimmune anti-B antiserum undergoing Poiseuille flow and observed using the traveling microtube technique. The mean forces separating the cells of individual doublets were found to be proportional to antiserum concentration from 0.73 to 3.56% v/v, normal forces increasing from 0.060 to 0.197 nN and shear forces from 0.023 to 0.072 nN. It was impossible to determine which force was responsible for break-up. Measurements of the doublets' mean dimensionless period of rotation indicated that doublets were rigidly linked.
Micropipet aspiration was applied to the same red cell-antibody system. Separation forces were $ sim2{1 over2}$ fold greater than for normal forces of the traveling microtube technique. Non-uniformity of red cell adhesiveness was also demonstrated.
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Moran, Carmel Mary. "The physical basis for ultrasonic investigation of human skin." Thesis, Institute of Cancer Research (University Of London), 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.246108.

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Quantock, Andrew James. "The stromal ultrastructure of normal and pathologic human corneas." Thesis, Open University, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.293665.

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Jones, Simon Richard. "Non-invasive analysis of human retinal and cortical visual function." Thesis, Imperial College London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312379.

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Books on the topic "Human Biophysics"

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Bhushan, Bharat. Biophysics of Human Hair. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-15901-5.

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Radiation biophysics. 2nd ed. San Diego, Calif: Academic Press, 1998.

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Alpen, Edward L. Radiation biophysics. Englewood Cliffs, N.J: Prentice-Hall, 1990.

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Radiation biophysics. Englewood Cliffs, N.J: Prentice Hall, 1990.

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Estes, James E. Actin: Biophysics, Biochemistry, and Cell Biology. Boston, MA: Springer US, 1994.

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Biophysics of human hair: Structural, nanomechanical, and nanotribological studies. Berlin: Springer, 2010.

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1958-, Abernethy Bruce, ed. The biophysical foundations of human movement. Champaign, IL: Human Kinetics, 1997.

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Glass, Leon. Theory of Heart: Biomechanics, Biophysics, and Nonlinear Dynamics of Cardiac Function. New York, NY: Springer New York, 1991.

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Schumacher, Paul Andrew. Biophysics and regulation of a whole-cell chloride current in human peripheral T lymphocytes. Ottawa: National Library of Canada, 1993.

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Determination of the moments of inertia of the human body and its limbs. Berlin: Springer-Verlag, 1988.

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Book chapters on the topic "Human Biophysics"

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Ravanelli, Nicholas, Coen C. W. G. Bongers, and Ollie Jay. "The Biophysics of Human Heat Exchange." In Heat Stress in Sport and Exercise, 29–43. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-93515-7_2.

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Schlessinger, Avner. "Characterizing the Structure, Function, and Evolution of Human Solute Carrier (SLC) Transporters Using Computational Approaches." In Springer Series in Biophysics, 23–57. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-53839-1_2.

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Althaus, Felix R., and Christoph Richter. "Poly(ADP-Ribose) in Inherited Human Diseases and Experimental Disease Models." In Molecular Biology Biochemistry and Biophysics, 114–25. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-83077-8_9.

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Abramson, Jeff, Aviv Paz, and Armand S. Vartanian. "Structures of the Prokaryotic Galactose Transporter vSGLT and Their Implications on Alternating Access Mechanism in Human SGLT1." In Springer Series in Biophysics, 59–78. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-53839-1_3.

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Torrens, Francisco, and Gloria Castellano. "Swine, Avian, and Human Flu, and Origins of a (H1N1) Flu Pandemic Strain." In Biochemistry, Biophysics, and Molecular Chemistry, 53–68. Series statement: Innovations in physical chemistry: monographic series: Apple Academic Press, 2020. http://dx.doi.org/10.1201/9780429284175-5.

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Fowler, Velia M. "Inhibition of Tropomyosin Binding to F-Actin by Tropomodulin, a New Tropomyosin-Binding Protein from the Human Erythrocyte Membrane." In Springer Series in Biophysics, 337–40. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-73925-5_60.

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Leondes, Cornelius T. "Artificial Neural Network Techniques in Human Mobility Rehabilitation." In Computational Methods in Biophysics, Biomaterials, Biotechnology and Medical Systems, 327–62. Boston, MA: Springer US, 2003. http://dx.doi.org/10.1007/0-306-48329-7_8.

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Fernandes, Sofia Rita, Ricardo Salvador, Mamede de Carvalho, and Pedro Cavaleiro Miranda. "Modelling Studies of Non-invasive Electric and Magnetic Stimulation of the Spinal Cord." In Brain and Human Body Modeling 2020, 139–65. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-45623-8_8.

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AbstractExperimental studies on transcutaneous spinal cord direct current and magnetic stimulation (tsDCS and tsMS, respectively) show promising results in the neuromodulation of spinal sensory and motor pathways, with possible clinical application in spinal functional rehabilitation. Modelling studies on the electric field (EF) distribution during tsDCS and tsMS can be powerful tools to understand the underlying biophysics and to guide stimulation protocols for a specific clinical target. In this chapter, we review modelling studies of tsDCS and report on our own modelling findings on tsDCS and tsMS. We discuss the main differences between the EF induced by these two stimulation techniques and the implications for clinical practice, addressing the relevance of modelling studies for more personalized target protocols and individualized dosing.
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Vaseashta, A. "Nanomaterials Nexus in Environmental, Human Health, and Sustainability." In NATO Science for Peace and Security Series B: Physics and Biophysics, 105–18. Dordrecht: Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-90-481-2523-4_9.

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Leondes, Cornelius T. "Wavelet and other Algorithm Techniques in Model Evaluation of Human Cerebral Functioning." In Computational Methods in Biophysics, Biomaterials, Biotechnology and Medical Systems, 707–37. Boston, MA: Springer US, 2003. http://dx.doi.org/10.1007/0-306-48329-7_19.

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Conference papers on the topic "Human Biophysics"

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WIJK, R. VAN. "PRESSURE-INDUCED ELECTRICAL SKIN CONDUCTIVITY AS A SENSITIVE MEAN FOR THE DETECTION BY HUMAN-HUMAN INTERACTION OF SUBTLE BODILY CHANGES." In Proceedings of the International School of Biophysics. WORLD SCIENTIFIC, 1998. http://dx.doi.org/10.1142/9789812816887_0031.

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Yi, Ji. "Elastic light scattering spectroscopy in living human retina (Conference Presentation)." In Biophysics, Biology and Biophotonics IV: the Crossroads, edited by Adam Wax and Vadim Backman. SPIE, 2019. http://dx.doi.org/10.1117/12.2513716.

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Doronin, Alexander, Holly E. Rushmeier, Igor Meglinski, and Alexander V. Bykov. "Cloud-based Monte Carlo modelling of BSSRDF for the rendering of human skin appearance (Conference Presentation)." In Biophysics, Biology and Biophotonics: the Crossroads, edited by Adam Wax and Vadim Backman. SPIE, 2016. http://dx.doi.org/10.1117/12.2214512.

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Risvas, Konstantinos, Michail Pavlou, Evangelia I. Zacharaki, and Konstantinos Moustakas. "Biophysics-based simulation of virtual human model interactions in 3D virtual scenes." In 2020 IEEE Conference on Virtual Reality and 3D User Interfaces Abstracts and Workshops (VRW). IEEE, 2020. http://dx.doi.org/10.1109/vrw50115.2020.00026.

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Pu, Yang, Binlin Wu, Jiangpeng Xue, Jason Smith, and Xin Gao. "Machine learning based analysis of human prostate cancer cell lines at different metastatic ability using native fluorescence spectroscopy with selective excitation wavelength." In Biophysics, Biology and Biophotonics III: the Crossroads, edited by Adam Wax and Vadim Backman. SPIE, 2018. http://dx.doi.org/10.1117/12.2281315.

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Firstova, Victoria V., Alexander L. Kravtsov, Tatyana P. Schmelkova, and Tatyana N. Shchukovskaya. "Evaluation of antitularaemia immunity via whole human blood leukocyte cytofluorometric analysis." In Saratov Fall Meeting 2004: Optical Technologies in Biophysics and Medicine VI, edited by Valery V. Tuchin. SPIE, 2005. http://dx.doi.org/10.1117/12.634771.

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Choi, Jeunghwan, and John C. Bischof. "Attachment State Shifts Viability Versus Cooling Rate (Inverted U Curve) During Freezing for Human Dermal Fibroblasts." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53156.

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A large number of studies in cryobiology have focused on understanding the underlying biophysics at the cellular level to help predict survival outcome after cryopreservation or cryosurgery. While this behavior is increasingly well studied and understood in cells gaps remain in our understanding of how cells in tissues behave which can hamper freezing applications in tissues. This study compares freezing behavior in cells in suspension vs. attached (a model tissue) state to investigate any differences in cellular behavior in these two states.
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Melnikov, A. G., A. B. Pravdin, V. I. Kochubey, and G. V. Melnikov. "Luminescent probe in the study of surfactant-induced structural changes in serum albumin in human blood plasma." In Saratov Fall Meeting 2004: Optical Technologies in Biophysics and Medicine VI, edited by Valery V. Tuchin. SPIE, 2005. http://dx.doi.org/10.1117/12.634650.

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Bashkatov, Alexey N., Elina A. Genina, Vyacheslav I. Kochubey, Valery V. Tuchin, Elena E. Chikina, Anatoly B. Knyazev, and Oleg V. Mareev. "Optical properties of human maxillary sinus mucosa and estimation of Methylene Blue diffusion coefficient in the tissue." In Saratov Fall Meeting 2004: Optical Technologies in Biophysics and Medicine VI, edited by Valery V. Tuchin. SPIE, 2005. http://dx.doi.org/10.1117/12.634835.

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Raufer, Stefan, and Hideko H. Nakajima. "Impedance measurements of the human cochlear partition." In TO THE EAR AND BACK AGAIN - ADVANCES IN AUDITORY BIOPHYSICS: Proceedings of the 13th Mechanics of Hearing Workshop. Author(s), 2018. http://dx.doi.org/10.1063/1.5038530.

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Reports on the topic "Human Biophysics"

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Huwiler, Kristin G., and Deane F. Mosher. Biophysical Studies of the Type 1 Repeats of Human Thrormbospondin-1 to Characterize the Structural Basis of Its Angiostatic Effect. Fort Belvoir, VA: Defense Technical Information Center, August 1997. http://dx.doi.org/10.21236/ada333301.

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