Academic literature on the topic 'Homeostasis'

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Journal articles on the topic "Homeostasis"

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Wang, Lin-Shu, and Peizheng Ma. "The homeostasis solution – Mechanical homeostasis in architecturally homeostatic buildings." Applied Energy 162 (January 2016): 183–96. http://dx.doi.org/10.1016/j.apenergy.2015.10.058.

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Kurniawan, Shahdevi Nandar. "INTRACELLULAR Ca2+ HOMEOSTASIS." MNJ (Malang Neurology Journal) 1, no. 1 (January 1, 2015): 36–45. http://dx.doi.org/10.21776/ub.mnj.2015.001.01.7.

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Rajkumar, R. Vinodh. "Perfect Homeostasis: pH." International Journal of Physiotherapy and Research 10, no. 1 (February 11, 2022): 4111–24. http://dx.doi.org/10.16965/ijpr.2021.213.

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Physiotherapists, Dieticians, and Exercise professionals have much better scope to become trailblazers in the forthcoming years to revamp the public health system and set spectacular trends in interdisciplinary health care for the people. Meanwhile, they must scrupulously engage in research pursuits and the dissemination of advanced knowledge in health and disease. A macrocosm of research literature in all the medical super-specializations are currently available but they would go futile if they are not unified and channelized for holistic and equitable health care. Human health is attained or maintained by acquiring homeostasis to coordinate and control a wide range of physiologic parameters within Narrow Homeostatic Range (NHR) that encompasses body temperature, pH, blood glucose level, blood cholesterol level, blood pressure, heart rate, respiratory rate, etc., Homeostasis tightly regulates NHR of all the physiologic parameters to develop homeostatic competence. Homeostatic competence is quite impossible without all the physiologic parameters harmoniously integrating with each other and working in their respective NHR. Physiologic parameters in NHR can be called as homeostatic factors. Deviation of even one physiologic parameter from its NHR could lead to temporary or permanent health disturbance due to disrupted homeostasis. But diseases tend to arise as a result of disturbance in all the physiologic parameters at the same time, though some or many of them could go unnoticed in the contemporary diagnostic procedures or due to lack of appropriate diagnosis. The homeostatic competence (or perfect homeostasis) of individuals that resists non-communicable diseases could also help resisting infectious diseases or vice versa. If only the data of physiologic parameters responsible for preventing non-communicable diseases are available, the health care professionals should be able to get a standpoint about the immunologic fitness of an individual (immunocompetent or immunocompromised) or if only the data of physiologic parameters responsible for immunologic fitness are available, the health care professionals should be able to get a standpoint about an individual’s ability to resist non-communicable diseases. These postulates on homeostatic competence can be made irrefutable by carefully reviewing the literature to establish associations between various homeostatic factors and the versatile roles played by each homeostatic factor in (i) preventing infectious diseases and non-communicable diseases (ii) maintaining pH and (iii) ensuring perfect homeostasis. Advancing Estimation and Gradation of Immunologic Status (AEGIS) can also be constructed putting together all homeostatic factors. Under the beneficial ecological conditions and lifestyle, human body as a biochemical machine would strive to adapt and converge all the versatile efforts of homeostatic factors to create perfect homeostasis for itself in association with a NHR for pH. Undoubtedly, at any age, Homeostatic Excellence Actuates Life Through Health (HEALTH) is naturally possible. KEY WORDS: Homeostasis, pH, Acid-base balance, Exercise, Nutrition, Ageing, Immunity, Infections, Non-communicable diseases, Public health
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Zakharov, V. M., and I. E. Trofimov. "Homeostatic mechanisms of biological systems: Development homeostasis." Russian Journal of Developmental Biology 45, no. 3 (May 2014): 105–16. http://dx.doi.org/10.1134/s1062360414030096.

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Meizlish, Matthew L., Ruth A. Franklin, Xu Zhou, and Ruslan Medzhitov. "Tissue Homeostasis and Inflammation." Annual Review of Immunology 39, no. 1 (April 26, 2021): 557–81. http://dx.doi.org/10.1146/annurev-immunol-061020-053734.

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There is a growing interest in understanding tissue organization, homeostasis, and inflammation. However, despite an abundance of data, the organizing principles of tissue biology remain poorly defined. Here, we present a perspective on tissue organization based on the relationships between cell types and the functions that they perform. We provide a formal definition of tissue homeostasis as a collection of circuits that regulate specific variables within the tissue environment, and we describe how the functional organization of tissues allows for the maintenance of both tissue and systemic homeostasis. This leads to a natural definition of inflammation as a response to deviations from homeostasis that cannot be reversed by homeostatic mechanisms alone. We describe how inflammatory signals act on the same cellular functions involved in normal tissue organization and homeostasis in order to coordinate emergency responses to perturbations and ultimately return the system to a homeostatic state. Finally, we consider the hierarchy of homeostatic and inflammatory circuits and the implications for the development of inflammatory diseases.
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Ziambaras, Konstantinos, Roberto Civitelli, and Stathis Papavasiliou. "Weightlessness and skeleton homeostasis." HORMONES 4, no. 1 (January 15, 2005): 18–27. http://dx.doi.org/10.14310/horm.2002.11139.

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S Prasad, Sanath. "Homeostasis - Balance, Equity, Equilibrium." International Journal of Science and Research (IJSR) 13, no. 3 (March 5, 2024): 1742–43. http://dx.doi.org/10.21275/es24326161131.

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Sumner, T., J. Hetherington, R. M. Seymour, L. Li, M. Varela Rey, S. Yamaji, P. Saffrey, et al. "A composite computational model of liver glucose homeostasis. II. Exploring system behaviour." Journal of The Royal Society Interface 9, no. 69 (February 8, 2012): 701–6. http://dx.doi.org/10.1098/rsif.2011.0783.

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Using a composite model of the glucose homeostasis system, consisting of seven interconnected submodels, we enumerate the possible behaviours of the model in response to variation of liver insulin sensitivity and dietary glucose variability. The model can reproduce published experimental manipulations of the glucose homeostasis system and clearly illustrates several important properties of glucose homeostasis—boundedness in model parameters of the region of efficient homeostasis, existence of an insulin sensitivity that allows effective homeostatic control and the importance of transient and oscillatory behaviour in characterizing homeostatic failure. Bifurcation analysis shows that the appearance of a stable limit cycle can be identified.
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Zhang, Huimin, Yang Li, Xiani Yao, Gang Liang, and Diqiu Yu. "POSITIVE REGULATOR OF IRON HOMEOSTASIS1, OsPRI1, Facilitates Iron Homeostasis." Plant Physiology 175, no. 1 (July 27, 2017): 543–54. http://dx.doi.org/10.1104/pp.17.00794.

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Pelletier, Luc G., Camille Guertin, J. Paige Pope, and Meredith Rocchi. "Homeostasis balance, homeostasis imbalance or distinct motivational processes? Comments on Marks (2015) ‘Homeostatic Theory of Obesity’." Health Psychology Open 3, no. 1 (January 13, 2016): 205510291562451. http://dx.doi.org/10.1177/2055102915624512.

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Dissertations / Theses on the topic "Homeostasis"

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Blanch, Graziela Torres [UNESP]. "Ajustes cardiovasculares e do equilibrio hidroeletrolítico induzidos por soluções hipertônicas em ratos com lesão do núcleo do trato solitário comissural." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/106675.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
O sistema nervoso central (SNC) tem um papel fundamental na regulação de mecanismos que controlam a osmolaridade dos líquidos corporais. O núcleo do trato solitário (NTS) é o sítio primário das aferências cardiovasculares e de osmorreceptores periféricos e se projeta à áreas prosencefálicas envolvidas com a regulação cardiovascular e do equilíbrio hidroeletrolítico. Demonstramos anteriormente que animais com lesão da porção comissural do NTS (commNTS) tem maior ingestão de água, natriurese e resposta pressora frente a sobrecarga intragástrica (ig) de NaCl 2 M. Os mecanismos responsáveis por estas alterações ainda não foram determinados. Uma vez que o estímulo com NaCl 2 M ig (2 ml) ativa osmorreceptores centrais e periféricos, não sabemos até o momento os efeitos da lesão do commNTS sobre as respostas observadas após a estimulação específica de osmorreceptores periféricos, que pode ser feita com NaCl 0,6 M ig. (2 ml). Desta forma os nossos objetivos foram: a) estudar os mecanismos que medeiam o aumento da pressão arterial e da natriurese após a sobrecarga de NaCl 2 M em animais com lesão do commNTS; b) verificar as alterações na expressão da proteína c-Fos após NaCl 2 M ig em ratos com lesão fictícia (sham) ou lesão do commNTS; c) verificar as alterações na expressão gênica no PVN após NaCl 2 M ig, d) estudar os efeitos na pressão arterial, na ingestão de água e na excreção renal subseqüentes a administração de NaCl 0,6 M ig, bem como os mecanismos responsáveis pelas alterações, em ratos com lesão fictícia (sham) ou lesão do commNTS; e) verificar as alterações na expressão da proteína c-Fos após NaCl 0,6 M ig em ratos com lesão fictícia (sham) ou lesão do commNTS. Ratos Holtzman (280-320 g) foram utilizados. A lesão eletrolítica...
The central nervous system has an important role controlling the mechanisms involved in the regulation of body fluid osmolality. The nucleus of the solitary tract (NTS) is the primary site of cardiovascular and peripheral osmoreceptors afferents and projects to prosencephalic areas involved in hydroelectrolytic balance and cardiovascular regulation. We have demonstrated that commissural NTS (commNTS) lesioned rats had an increase in arterial pressure and a greater increase in water intake and natriuresis after 2 M NaCl intragastric (ig) load. The mechanisms involved in these responses are not known. Since 2 M NaCl ig (2 ml) activates central and peripheral osmoreceptors, it is not known the effects of the commNTS lesion on the responses induced only by the activation of the peripheral osmoreceptors, which can be done by 0.6 M NaCl (2 ml) ig. Thus, the aims of this study were: a) to study the mechanisms involved in the increase of the arterial pressure and natriuresis in commNTS lesioned rats after 2 M NaCl ig; b) to verify the changes in c-Fos expression after 2 M NaCl ig in sham and commNTS lesioned rats; c) to verify the changes in gene expression in PVN after 2 M NaCl ig in naïve rats; d) to study the effects on arterial pressure, water intake and renal excretion after 0.6 M NaCl, as well as, the mechanisms involved in these responses, in sham and in commNTS lesioned rats; e) to verify the changes in c-Fos expression after 0.6 M NaCl ig in sham and commNTS lesioned rats. Male Holtzman rats (280-320 g) were used. Electrolytic lesion of the commNTS and all experiments were be performed in chronic period of lesion (14 to 21 days. For the lesion, a partial craniotomy of the occipital bone was performed, and the dorsal surface of the brainstem was exposed. The electrolytic lesion was performed using... (Complete abstract click electronic access below)
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Kisko, Mushtak. "Study of Physiological and molecular mechanisms underlying the co-regulation between phosphate and zinc homeostasis in plants." Thesis, Montpellier, SupAgro, 2018. http://www.theses.fr/2018NSAM0004/document.

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Chez les plantes, alors qu'il est clair que l'homéostasie des différents nutriments est fortement dépendante les uns des autres, ils sont généralement étudiés indépendamment les uns des autres. Étant donné la rareté des études antérieures évaluant la signification biologique de l'interaction de l'homéostasie des nutriments minéraux, on en sait très peu sur la base génétique et moléculaire de ces interactions. Au cours de ma thèse, nous avons progressé de manière significative vers une compréhension plus intégrative du problème et identifié les bases moléculaires et génétiques d'une interaction nutritive très importante et conservée: l'interaction du zinc et du phosphate, dans laquelle les gènes PHO1;H3 et Lyso PhosphatidylCholine (PC) AcylTransferase 1 (LPCAT1) jouent des rôles centraux. En combinant des approches de biologie systémique et de biologie fonctionnelle, nous avons identifié le module fonctionnel (quatre facteurs transcriptions) qui régule l'expression de PHO1; H3 en condition de carence en Zn. Suite à une étude de génétique d’association (GWAS) nous avons découvert un nouveau rôle du gène LPCAT1 dans l’accumulation du phosphate en conditions de carence en Zn, Ensuite, nous avons déterminé une voie moléculaire complète contrôlant l'expression de ce gène. Ce travail nous permis de révéler un lien fondamental entre le métabolisme des phospholipides et l'interaction homéostasie Pi-Zn, et de proposer un nouveau rôle pour Lyso-PC et PC dans le contrôle de l'interaction homéostasie macro- et micronutriments chez les plantes. Les résultats obtenus offrent une nouvelle perspective pour élabore des nouvelles stratégies pour améliorer l’accumulation de Pi dans les plantes via la modulation de la voie de signalisation de la carence en Zn
In plants, while it is clear the homeostasis of different nutrients is highly dependent on each other, they are usually studied independent of each other. Given the paucity of past studies assessing the biological significance of mineral nutrient homeostasis interaction, very little is known about the genetic and molecular basis of such interactions. During my thesis, we made significant progress in going towards a more integrative comprehension of the problem and identify the molecular and genetic bases for a highly important and conserved nutrients interaction: the interaction of zinc and phosphate. First, using the phosphate transporter PHO1;H3 as entry molecular point, and by combining system biology and functional genomics approaches we have identified the functional module (four transcription factors) that regulates the expression and activity of PHO1;H3 under Zn deficiency leading to control Pi accumulation in shoots. Second, following our discovery of Lyso PhosphatidylCholine (PC) AcylTransferase 1 (LPCAT1) using genome-wide association studies (GWAS), we determined complete molecular pathway controlling the expression of this gene. We further uncovered a fundamental link between phospholipid metabolism and Pi-Zn homeostasis interaction via LPCAT1, which lays the foundations to explore a new role for Lyso-PC and PC in control of macro- and micronutrients homeostasis interaction. Taken together, our discoveries offer a new perspective on how to improve Pi content in plants, as our findings suggests that modulating the Zn-deficiency signalling pathway might be a good and simple approach for that
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Blanch, Graziela Torres. "Ajustes cardiovasculares e do equilibrio hidroeletrolítico induzidos por soluções hipertônicas em ratos com lesão do núcleo do trato solitário comissural /." Araraquara : [s.n.], 2010. http://hdl.handle.net/11449/106675.

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Orientador: Débora Simões de Almeida Colombari
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Banca: Cássia Marta de Toledo Bermagaschi
Banca: Vagner Roberto Antunes
Banca: Lucila Leico Kagohara Elias
Resumo: O sistema nervoso central (SNC) tem um papel fundamental na regulação de mecanismos que controlam a osmolaridade dos líquidos corporais. O núcleo do trato solitário (NTS) é o sítio primário das aferências cardiovasculares e de osmorreceptores periféricos e se projeta à áreas prosencefálicas envolvidas com a regulação cardiovascular e do equilíbrio hidroeletrolítico. Demonstramos anteriormente que animais com lesão da porção comissural do NTS (commNTS) tem maior ingestão de água, natriurese e resposta pressora frente a sobrecarga intragástrica (ig) de NaCl 2 M. Os mecanismos responsáveis por estas alterações ainda não foram determinados. Uma vez que o estímulo com NaCl 2 M ig (2 ml) ativa osmorreceptores centrais e periféricos, não sabemos até o momento os efeitos da lesão do commNTS sobre as respostas observadas após a estimulação específica de osmorreceptores periféricos, que pode ser feita com NaCl 0,6 M ig. (2 ml). Desta forma os nossos objetivos foram: a) estudar os mecanismos que medeiam o aumento da pressão arterial e da natriurese após a sobrecarga de NaCl 2 M em animais com lesão do commNTS; b) verificar as alterações na expressão da proteína c-Fos após NaCl 2 M ig em ratos com lesão fictícia (sham) ou lesão do commNTS; c) verificar as alterações na expressão gênica no PVN após NaCl 2 M ig, d) estudar os efeitos na pressão arterial, na ingestão de água e na excreção renal subseqüentes a administração de NaCl 0,6 M ig, bem como os mecanismos responsáveis pelas alterações, em ratos com lesão fictícia (sham) ou lesão do commNTS; e) verificar as alterações na expressão da proteína c-Fos após NaCl 0,6 M ig em ratos com lesão fictícia (sham) ou lesão do commNTS. Ratos Holtzman (280-320 g) foram utilizados. A lesão eletrolítica... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: The central nervous system has an important role controlling the mechanisms involved in the regulation of body fluid osmolality. The nucleus of the solitary tract (NTS) is the primary site of cardiovascular and peripheral osmoreceptors afferents and projects to prosencephalic areas involved in hydroelectrolytic balance and cardiovascular regulation. We have demonstrated that commissural NTS (commNTS) lesioned rats had an increase in arterial pressure and a greater increase in water intake and natriuresis after 2 M NaCl intragastric (ig) load. The mechanisms involved in these responses are not known. Since 2 M NaCl ig (2 ml) activates central and peripheral osmoreceptors, it is not known the effects of the commNTS lesion on the responses induced only by the activation of the peripheral osmoreceptors, which can be done by 0.6 M NaCl (2 ml) ig. Thus, the aims of this study were: a) to study the mechanisms involved in the increase of the arterial pressure and natriuresis in commNTS lesioned rats after 2 M NaCl ig; b) to verify the changes in c-Fos expression after 2 M NaCl ig in sham and commNTS lesioned rats; c) to verify the changes in gene expression in PVN after 2 M NaCl ig in naïve rats; d) to study the effects on arterial pressure, water intake and renal excretion after 0.6 M NaCl, as well as, the mechanisms involved in these responses, in sham and in commNTS lesioned rats; e) to verify the changes in c-Fos expression after 0.6 M NaCl ig in sham and commNTS lesioned rats. Male Holtzman rats (280-320 g) were used. Electrolytic lesion of the commNTS and all experiments were be performed in chronic period of lesion (14 to 21 days. For the lesion, a partial craniotomy of the occipital bone was performed, and the dorsal surface of the brainstem was exposed. The electrolytic lesion was performed using... (Complete abstract click electronic access below)
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Val, Casals Maria 1993. "Circadian regulation of macrophages in homeostasis and disease." Doctoral thesis, Universitat Pompeu Fabra, 2020. http://hdl.handle.net/10803/669532.

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Els ritmes circadians són oscil·lacions diàries en paràmetres fisiològics necessaris per a què els organismes adaptin la seva activitat als cicles de llum i foscor. A nivell molecular, la maquinària circadiana consisteix en bucles oscil·latoris de traducció-transcripció dirigides per l’activitat de les proteïnes BMAL1 i CLOCK de manera autònoma a cada cèl·lula. La maquinària circadiana regula l’activitat de diversos tipus de cèl·lules immunitàries, inclosos els macròfags. Concretament, BMAL1 pot controlar la magnitud diària de les respostes inflamatòries dels macròfags. En el present treball, es caracteritza la regulació circadiana dels macròfags en contextos encara no explorats. Hem analitzat l’expressió i els patrons oscil·ladors dels components del rellotge en poblacions de macròfags i també hem valorat el paper potencial dels rellotges en les funcions dels macròfags. Presentem resultats identificant aspectes de la funció del rellotge en macròfags que poden ajudar a comprendre la influència dels ritmes circadians en la modulació de respostes immunitàries innates.
Circadian rhythms are daily oscillations in physiological parameters required for organisms to adapt their activity to cycles of light and darkness. At the molecular level, the circadian machinery consists of cell-autonomous transcription-translation oscillation loops led by the activity of BMAL1 and CLOCK proteins. The circadian machinery regulates the activity of diverse immune cell types, including macrophages. Specifically, BMAL1 can control the daily magnitude of macrophage inflammatory responses. In the present work we characterize the circadian regulation of macrophages in yet unexplored contexts. We have analyzed the expression and oscillatory patterns of clock components in macrophage populations, and also assessed the potential role of clocks in macrophage functions. We present results identifying aspects of clock function in macrophages that can help understand the influence of circadian rhythms in the modulation of innate immune responses.
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Wassif, Christopher A. "Dysregulation of cholesterol homeostasis." Thesis, University of Oxford, 2015. http://ora.ox.ac.uk/objects/uuid:da3374f0-9285-4490-b2e7-af493556d925.

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Cholesterol plays a critical role in the health and normal function of every mammalian cell. Cholesterol has multiple cellular functions including maintenance of cell membrane stability and fluidity, steroid hormone and bile acid synthesis, and membrane receptor signaling. As with any critical metabolite, cholesterol is highly regulated. I will detail my research focusing on the two prevalent disorders of cholesterol homeostasis. The first is a disorder of cholesterol biosynthesis, Smith-Lemli-Opitz syndrome (SLOS), and the second a disorder of cholesterol trafficking, Niemann-Pick disease, type C1 (NPC). I have identified a unique cellular phenotypic overlap between these two previously unrelated disorders. Specifically, increasing concentrations of the precursor sterol present in SLOS, 7-dehydrocholesterol, leads to the induction of an NPC-like cellular phenotype. Aspects of the NPC cellular phenotype that can be induced in SLOS fibroblasts include lysosomal storage of unesterified cholesterol, sphingosine, and glycosphingolipids. Also, similar to what is observed in NPC, dysregulation of acidic calcium stores is present in SLOS. Further research indicates that this cellular phenotype extends into both the mouse models of SLOS and the patients. The dysregulation of cholesterol trafficking in SLOS cells likely decreases cellular cholesterol bioavailabilty and thus potentially limits the therapeutic efficacy of dietary cholesterol supplementation in SLOS patients. I also show that treatment of SLOS cells with miglustat, an established therapy for NPC, ameliorates the NPC-like cellular phenotype and thus may have therapeutic benefit in SLOS. The incidence of both SLOS and NPC has been the subject of debate. Thus, using data generated from massively parallel sequencing of the human exome, I demonstrate that the previously predicted incidence of SLOS of 1:40,000 births is likely correct, but call into question the predicted NPC rate of 1:120,000 . In fact, NPC maybe closer to a rate of 1:40,000. The role of oxysterols in the teratogenicity of SLOS and the underlying secondary storage of lipids in the phenotypic presentation of SLOS has been investigated.
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Davies, Luke C. "Control of macrophage homeostasis." Thesis, Cardiff University, 2014. http://orca.cf.ac.uk/112185/.

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Tissue resident macrophages are extremely heterogeneous, which reflects their unique microenvironments and tissue specific functions. They are a constituent of all tissues, and are involved in homeostatic processes and inflammatory disease. Recent studies have shown that select tissue resident macrophage populations, such as Langerhans cells of the skin and microglia of the brain, are able to self-renew independently from the bone marrow. This is contrary to the prevailing model macrophage origins, the ‘mononuclear phagocyte system’, which dictates that all macrophages are derived from bone marrow monocytes. The work carried out in this thesis investigated the self-renewing potential of peritoneal tissue resident macrophages, and its control. Several novel discoveries were made: i) peritoneal resident macrophages proliferate at low levels to maintain their numbers during homeostasis, at higher levels during neonatal growth, and undergo a burst in proliferation during acute inflammation to restore their depleted population; ii) renewal of peritoneal resident macrophages during an acute inflammatory episode was found to be independent from the bone marrow, and dependent upon macrophage colony stimulating factor, but importantly, not interleukin-4; iii) Monocyte-derived macrophages could also proliferate within an inflammatory lesion. Collectively, these observations challenge the dogma of the mononuclear phagocyte system: they demonstrate that in vascular tissues, tissue resident macrophages could self-renewal independently of monocytes, and that monocyte-derived cells are not terminally-differentiated. Additional work leading up to these studies implicated Gata6 as a peritoneal macrophage-specific transcription factor. In this thesis, Gata6 was found to be necessary for peritoneal macrophage phenotype, normal proliferation, euploidy, and normal responses to inflammation. In summary, these studies demonstrate not only are macrophages capable of self-renewal, but this is dependent upon discrete transcriptional control. Understanding the molecular controls of tissue macrophage heterogeneity and renewal could provide novel avenues for the therapeutic manipulation of their activities.
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Hoshi, Rosangela Akemi. "Análise da variabilidade da frequência cardíaca, variáveis cardiopulmonares e catecolaminas plasmáticas durante recuperação pós-exercício." Faculdade de Medicina de São José do Rio Preto, 2015. http://hdl.handle.net/tede/253.

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Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES
Introduction: Exercises promote changes in the Autonomic Nervous System, the mainly responsible for neurodegenerative functions. Due to its importance, several methods are used in evaluation such as Heart Rate Variability (HRV) analysis, considered an indirect technique to assess autonomic functions, but its use is still questioned. Objectives: To analyze the correlation between HRV indices and concentration of epinephrine and norepinephrine, and observe post-exercise recovery, by HRV linear and nonlinear indices and cardiopulmonary parameters. Methods: 28 participants, divided into two groups (N = 14) had their recovery after exercise evaluated. One group performed submaximal effort (55% V̇O2peak), for 5 minutes, and the other, supramaximal (110% of peak V̇O2) until exhaustion. During 90 minutes post-exercise, blood samples were collected, cardiopulmonary variables were registered and HRV was analyzed. Results: Between baseline and immediately postexercise, we detected that adrenaline and noradrenaline showed significant nonlinear correlation with RR intervals, heart rate, HRV linear indices and nonlinear parameters related to complexity and fractality. After exercise performed at 55% of peak V̇O2, recovery was observed between 30 and 60 minutes, whereas for exercise at 110%, 90 minutes were not enough for returning of variables to baseline levels. Conclusions: Plasma catecholamine concentrations after exercise presented correlation with HRV linear indices and nonlinear parameters related to complex and fractal characteristics of heartbeats, especially the Lyapunov exponent. The variables recovery occurred at different times, but the changes caused by supramaximal exercise were more expressive and lasting.
Introdução: A realização de exercícios físicos promove alterações no sistema nervoso autônomo, principal responsável pelas funções neurovegetativas. Devido à sua importância, diversos métodos são utilizados para avaliação, como a análise da Variabilidade da Frequência Cardíaca (VFC), considerada uma técnica indireta de acesso ao funcionamento autonômico, porém seu emprego é ainda questionado. Objetivos: analisar a correlação entre índices de VFC e concentração de adrenalina e noradrenalina, e observar a recuperação pós-exercício, a partir dos índices lineares e não lineares de VFC e de parâmetros cardiopulmonares. Métodos: 28 participantes, divididos em dois grupos (N=14), foram submetidos à avaliação da recuperação após exercício. Um grupo realizou esforço submáximo (55% do V̇O2pico), por 5 minutos, e o outro, supramáximo ( 110% do V̇O2pico) até a exaustão. Durante 90 minutos pós-exercício foram realizadas coletas sanguíneas, registros das variáveis cardiopulmonares e análise da VFC. Resultados: No período entre o basal e imediatamente após o exercício, detectou-se que adrenalina e noradrenalina apresentaram correlações não lineares significantes com intervalos R-R, frequência cardíaca, índices lineares de VFC e parâmetros não lineares relacionados à complexidade e fractalidade. Após exercício realizado a 55% do V̇O2pico, a recuperação foi verificada entre 30 e 60 minutos, enquanto que para o esforço a 110%, 90 minutos não foram suficientes para o retorno das variáveis aos níveis basais. Conclusões: Concentrações de catecolaminas plasmáticas após exercícios apresentam correlação com índices lineares de VFC e parâmetros não lineares relacionados às características complexas e fractais dos batimentos cardíacos, sobretudo o expoente de Lyapunov. A recuperação das variáveis analisadas ocorreu em tempos diferentes, porém as alterações promovidas pelo exercício supramáximo foram muito mais expressivas e duradouras.
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Smith, Kirsty Louise. "Metabolic hormones and energy homeostasis." Thesis, Imperial College London, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.411789.

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Allstaff, Alison Jane. "Novel factors in bone homeostasis." Thesis, University of Aberdeen, 2010. http://digitool.abdn.ac.uk:80/webclient/DeliveryManager?pid=128211.

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Microarray analysis of gene expression in osteoblasts from patients with osteoporosis (OP) and osteoarthritis (OA) showed that 115 genes were robustly differentially expressed (P<0.05). Functional annotation clustering revealed cell adhesion to be the gene ontology classification most likely to be associated with this gene list. In addition scrutiny of the list revealed several genes with strong biological support for the involvement in bone homeostasis (FOSL1, BMPR2 and TGFBR1). Real -time PCR validated the trends seen in the microarray analysis, but failed to reach statistical significance for any of the genes examined. This analysis supports the value and potential of larger scale comparison of gene expression in OA and OP osteoblasts as a method for identifying novel factors involved in bone homeostasis. The cannabinoid system has recently been identified as involved in the regulation of bone homeostasis. In vitro investigation revealed that although cannnabinoid receptor agonists N-arachidonoylethanolamine (AEA), 2-arachidonoylglycerol (2-AG) and JWH015 had no effect on metabolic activity, cell number, or alkaline phosphatase activity of calvarial mouse osteoblasts there were changes in gene expression. RankL expression was reduced relative to Opg expression by both JWH015 and AEA. Preliminary results indicate that JWH015 was also capable of increasing PPARγ expression which could alter the balance of osteoblastic and adipocytic differentiation of mesenchymal stem cells (MSC). This could have implications for use of these drugs in vivo. Using the 3T3-F442A cell line to develop a model of MSC differentiation highlighted difficulties associated with using cell models. Necessary additional factors required to induce differentiation of a cell line compared to a primary cell make interpretation of results more complicated. This model also highlighted that alkaline phosphatase and osteocalcin (markers usually used to identify osteogenic differentiation) were expressed during adipocytic differentiation. Future use of such markers in MSC models should be closely scrutinized.
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Thompson, Shirley Patricia. "Calcium homeostasis in the elderly." Thesis, University of Nottingham, 1989. http://eprints.nottingham.ac.uk/14012/.

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The initial aims of this investigation were to develop a reliable assay system for measuring serum 1,Z5-dihydroxyvitamin D [1,Z5(OH)ZD] concentrations and to establish a normal range in young healthy adults. Compared with young healthy individuals, the elderly population are indeed vitamin D deficient. Vitamin D deficiency was also demonstrated in a group of elderly osteomalacic patients. Slight improvements in osteomalacia was achieved by one month of treatment with vitamin D3' or alphacalcidiol with or without calcium supplements. The improvements were small and occured slowly. A significant increase in the strength of bone seems unlikely to occur in the short term. On the present evidence the combination of alphacalcidiol and calcium supplements seems no better than vitamin D3 or alphacalcidiol alone although it may require closer monitoring to avoid hypercalcaemia. In a group of elderly patients with osteoporosis and femoral neck fracture (FNF), serum osteocalcin concentrations rose significantly in the first week after fracture fixation. The change in osteocalcin correlated well (p < 0.001) with the change in serum 1,Z5(OH)ZD concentration. Histomorphometric measurements of the extent of osteoid correlated better with osteocalcin than alkaline phosphatase. Serum concentrations of 1,Z5(OH)ZD were also reduced in elderly patients with FNF irrespective of the presence of osteomalacia and therefore cannot be used as a screening test for osteomalacia in this patient group. Reduction of 1,Z5(OH)ZD was not due to a reduction in vitamin D binding protein. It is suggested that the low rate of bone turnover in these elderly patients reduces the requirement of vitamin D. Of the ten elderly patients who had underwent laryngo pharyngeal surgery all developed hypocalcaemia. This immediate post-operative decrease, due to a rapid reduction in circulating PTH concentrations, lead to an overall increase in urinary calcium excretion. Serum concentration of 1,25(OH)2D also fell postoperatively thus potentiating the hypocalcaemic state in these patients. Thus, it is important to give parenteral feeding supplemented with calcium and vitamin D, preferably alphacalcidiol. If delayed then profound as well as prolonged hypocalcaemia can occur. The human osteosarcoma cell 20S metabolised 25(OH)D3 in a substrate concentration and time dependent manner to produce products which were secreted into the extracellular medium. These products eluted from HPLC with a retention time coincident with 24,25(OH)2D3 and exhibited an UV absorption spectrum characteristic of a vitamin D sterol. Mass spectroscopy analysis indicated at least two products were synthesised by the cells. One was identical to 24,25(OH)2D3; the other appeared to be an unsaturated trihydroxylated derivative of vitamin D3.
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Books on the topic "Homeostasis"

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Gelissen, Ingrid C., and Andrew J. Brown, eds. Cholesterol Homeostasis. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-6875-6.

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Snow, Andrew L., and Michael J. Lenardo, eds. Immune Homeostasis. Totowa, NJ: Humana Press, 2013. http://dx.doi.org/10.1007/978-1-62703-290-2.

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Carafoli, Ernesto, and Joachim Krebs, eds. Calcium Homeostasis. Berlin, Heidelberg: Springer Berlin Heidelberg, 2000. http://dx.doi.org/10.1007/978-3-642-58306-3.

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Pool, Ontario Assessment Instrument, ed. Homeostasis: Draft. Toronto: Minister of Education, Ontario, 1989.

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Kumar, Vijay, ed. Immune Homeostasis. New York, NY: Springer US, 2024. http://dx.doi.org/10.1007/978-1-0716-3754-8.

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Smith, Robert Elijah. Mammalian homeostasis. Burlington, N.C: Carolina Biological Supply Co., 1987.

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Banfalvi, Gaspar. Homeostasis - Tumor - Metastasis. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-007-7335-6.

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Jeong, Jeeyon, ed. Plant Iron Homeostasis. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-3183-6.

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1937-, Brenner Barry M., and Stein Jay H. 1937-, eds. Body fluid homeostasis. New York: Churchill Livingstone, 1987.

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Panda, Sanjib Kumar, and Yoshiharu Y. Yamamoto, eds. Redox Homeostasis in Plants. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-319-95315-1.

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Book chapters on the topic "Homeostasis"

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Soper, Roland. "Homeostasis." In Human Biology GCSE, 111–31. London: Macmillan Education UK, 1992. http://dx.doi.org/10.1007/978-1-349-12789-4_8.

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Kilgour, O. F. G. "Homeostasis." In Work Out Biology GCSE, 159–71. London: Macmillan Education UK, 1987. http://dx.doi.org/10.1007/978-1-349-09450-9_9.

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Caon, Martin. "Homeostasis." In Examination Questions and Answers in Basic Anatomy and Physiology, 139–49. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-75599-1_6.

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Capinera, John L., Thomas O. Crist, John B. Heppner, Minos E. Tzanakakis, Severiano F. Gayubo, Aurélien Tartar, Pauline O. Lawrence, et al. "Homeostasis." In Encyclopedia of Entomology, 1832. Dordrecht: Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6359-6_1365.

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Gaab, Jens. "Homeostasis." In Encyclopedia of Behavioral Medicine, 1080. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-39903-0_22.

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Orbell, Sheina, Havah Schneider, Sabrina Esbitt, Jeffrey S. Gonzalez, Jeffrey S. Gonzalez, Erica Shreck, Abigail Batchelder, et al. "Homeostasis." In Encyclopedia of Behavioral Medicine, 978. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-1005-9_22.

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Moreno, Alvaro, and Kepa Ruiz-Mirazo. "Homeostasis." In Encyclopedia of Astrobiology, 1. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-642-27833-4_730-2.

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Cummins, Robert A. "Homeostasis." In Encyclopedia of Quality of Life and Well-Being Research, 2901–4. Dordrecht: Springer Netherlands, 2014. http://dx.doi.org/10.1007/978-94-007-0753-5_1303.

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Stout, G. W., and N. P. O. Green. "Homeostasis." In Work Out Biology A Level, 166–76. London: Macmillan Education UK, 1995. http://dx.doi.org/10.1007/978-1-349-13844-9_11.

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Moreno, Alvaro, and Kepa Ruiz-Mirazo. "Homeostasis." In Encyclopedia of Astrobiology, 1113–14. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-662-44185-5_730.

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Conference papers on the topic "Homeostasis"

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Polyak, Emil. "Homeostasis." In SIGGRAPH '20: Special Interest Group on Computer Graphics and Interactive Techniques Conference. New York, NY, USA: ACM, 2020. http://dx.doi.org/10.1145/3386567.3388559.

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Zeinali-Davarani, Shahrokh, and Seungik Baek. "Testing Different Hypotheses of Vascular Homeostasis Based on Mechanical Stress or Strain in Image-Based Models Using an Inverse Method." In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53213.

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Various hypotheses are previously suggested to describe the tendency of vascular tissue to adapt in response to alterations in mechanical stimuli. It is still a matter of controversy which mechanical quantity governs or correlates well with the adaptation, contributing to the mechanical homeostasis. A computational tool that can distinguish between different hypotheses under various physiological conditions may help better understanding of the governing rules. Recently, an inverse optimization method has been developed to estimate the optimal spatial distributions of arterial wall thickness and material anisotropy of image-based models while satisfying a homeostatic condition assumed [1]. The same numerical method can be utilized to investigate the consequent optimal structures resulting from different hypotheses for the mechanical homeostasis. We consider three hypotheses for a homeostatic state based on intramural stress or cyclic stretch and examine their effects on the optimized distributions of thickness and anisotropy. The results show the capability of the presented method in discriminating different hypotheses of vascular homeostasis with image-based models, the validity of which requires more experimental data.
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Roy, Sudip, Lucja Kot, Gabriel Bender, Bailu Ding, Hossein Hojjat, Christoph Koch, Nate Foster, and Johannes Gehrke. "The Homeostasis Protocol." In SIGMOD/PODS'15: International Conference on Management of Data. New York, NY, USA: ACM, 2015. http://dx.doi.org/10.1145/2723372.2723720.

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Domin, C., and L. Medlin. "Homeostasis and perpetual change." In ECO-ARCHITECTURE 2010. Southampton, UK: WIT Press, 2010. http://dx.doi.org/10.2495/arc100031.

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Hunley, S. C., S. Kwon, and S. Baek. "Influence of Surrounding Tissues on Biomechanics of Aortic Wall: A Feasibility Study of Mechanical Homeostasis." In ASME 2010 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/sbc2010-19264.

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Previous research in cardiovascular mechanics has shown that mechanical factors strongly influence the growth and remodeling of blood vessels, thereby leading the hypothesis of mechanical homeostasis as a mechanism of regulating vascular adaptation [1]. Nevertheless, this assumption is mostly based on stress analysis of an idealized blood vessel. However, for the aorta, its motion is considerably limited by the surrounding tissue during the cardiac cycle, with the thickness of the posterior side significantly thinner than the anterior side (Fig. 1). In this work, we test the possibility of the existence of a homeostatic level of stress in the aorta using a linear plane-strain model that accounts for thickness variations and surrounding tissues. The results of this computational study show that the surrounding tissue, together with thickness variations, homogenizes the stress level of blood vessel under a physiological pressure, which implies that the mechanical homeostasis is still feasible even with thickness variations and the influence of the surrounding tissues in the aorta.
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Kiryu, Tohru. "Handling Risk Homeostasis in Biofunctions*." In 2020 IEEE 2nd Global Conference on Life Sciences and Technologies (LifeTech). IEEE, 2020. http://dx.doi.org/10.1109/lifetech48969.2020.1570618241.

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Renaud, Karen, and Merrill Warkentin. "Risk Homeostasis in Information Security." In NSPW '17: 2017 New Security Paradigms Workshop. New York, NY, USA: ACM, 2017. http://dx.doi.org/10.1145/3171533.3171534.

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Clark, Sean, and Stephen Scrivener. "Rebuilding Stephen Scrivener's Homeostasis Artwork." In Proceedings of EVA London 2023. BCS Learning & Development, 2023. http://dx.doi.org/10.14236/ewic/eva2023.15.

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Tacail, Théo, Jamie Lewis, Thomas Tütken, Christopher D. Coath, Nicholas Lloyd, Marcus Clauss, and Tim Elliott. "Potassium Stable Isotope Homeostasis in Vertebrates." In Goldschmidt2020. Geochemical Society, 2020. http://dx.doi.org/10.46427/gold2020.2524.

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Oka, Mizuki, Hirotake Abe, and Takashi Ikegami. "Dynamic Homeostasis in Packet Switching Networks." In European Conference on Artificial Life 2015. The MIT Press, 2015. http://dx.doi.org/10.7551/978-0-262-33027-5-ch020.

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Reports on the topic "Homeostasis"

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Kilduff, Thomas S. Neurobiological Correlates of Sleep Homeostasis. Fort Belvoir, VA: Defense Technical Information Center, January 2001. http://dx.doi.org/10.21236/ada391757.

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Young, Jamey D., and Young M. Whang. Targeting Redox Homeostasis in LKB1-deficient NSCLC. Fort Belvoir, VA: Defense Technical Information Center, September 2014. http://dx.doi.org/10.21236/ada614534.

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Blumwald, Eduardo, and Avi Sadka. Sugar and Acid Homeostasis in Citrus Fruit. United States Department of Agriculture, January 2012. http://dx.doi.org/10.32747/2012.7697109.bard.

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Citrus fruit quality standards have been determined empirically, depending on species and on the particular growing regions. In general, the TSS (total soluble solids) to total acidity (TA) ratio determines whether citrus fruit can be marketed. Soluble sugars account for most of the TSS during harvest while TA is determined almost solely by the citric acid content, which reaches levels of 1-5% by weight in many cultivated varieties. Acid and sugar homeostasis in the fruit is critical for the management of existing cultivars, the development of new cultivars, the improvement of pre- and post-harvest strategies and the control of fruit quality and disorders. The current proposal (a continuation of a previous proposal) aimed at: (1) completing the citrus fruit proteome and metabolome, and establish a citrus fruit functional database, (2) further characterization of the control of fruit acidity by studying the regulation of key steps affecting citrate metabolism, and determine the fate of citrate during acid decline stage, and (3) Studying acid and sugar homeostasis in citrus fruits by characterizing transport mechanisms across membranes. These aims were completed as the following: (1) Our initial efforts were aimed at the characterization and identification of citric acid transporters in citrus juice cells. The identification of citrate transporters at the vacuole of the citrus juice cell indicated that the steady-state citrate cytosolic concentration and the action of the cytosolic aconitase were key elements in establishing the pH homeostat in the cell that regulates the metabolic shift towards carbon usage in the fruit during the later stages of fruit development. We focused on the action of aconitase, the enzyme mediating the metabolic use of citric acid in the cells, and identified processes that control carbon fluxes in developing citrus fruits that control the fruit acid load; (2) The regulation of aconitase, catalyzing a key step in citrate metabolism, was further characterized by using two inhibitors, citramalte and oxalomalte. These compounds significantly increased citrate content and reduced the enzyme’s activity. Metabolite profiling and changes of amino-acid metabolizing enzymes in oxalomalate- treated cells suggested that the increase in citrate, caused by aconitase inhibition, induces amino acid synthesis and the GABA shunt, in accordance with the suggested fate of citrate during the acid decline stage in citrus fruit. (3) We have placed a considerable amount of time on the development of a citrus fruit proteome that will serve to identify all of the proteins in the juice cells and will also serve as an aid to the genomics efforts of the citrus research community (validating the annotation of the fruit genes and the different ESTs). Initially, we identified more than 2,500 specific fruit proteins and were able to assign a function to more than 2,100 proteins (Katz et al., 2007). We have now developed a novel Differential Quantitative LC-MS/MS Proteomics Methodology for the identification and quantitation of key biochemical pathways in fruits (Katz et al., 2010) and applied this methodology to identify determinants of key traits for fruit quality (Katz et al., 2011). We built “biosynthesis maps” that will aid in defining key pathways associated with the development of key fruit quality traits. In addition, we constructed iCitrus (http://wiki.bioinformatics.ucdavis.edu/index.php/ICitrus), a “functional database” that is essentially a web interface to a look-up table that allows users to use functional annotations in the web to identify poorly annotated citrus proteins. This resource will serve as a tool for growers and field extension specialists.
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R. Nebreda, Ángel. Señalización de estrés en la homeostasis tumoral: implicaciones terapéuticas. Sociedad Española de Bioquímica y Biología Molecular, October 2017. http://dx.doi.org/10.18567/sebbmdiv_anc.2017.10.1.

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Kongara, Sameera. Role of Autophagy in Keratin Homeostasis in Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, December 2012. http://dx.doi.org/10.21236/ada583662.

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Kongara, Sameera. Role of Autophagy in Keratin Homeostasis in Breast Cancer. Fort Belvoir, VA: Defense Technical Information Center, March 2014. http://dx.doi.org/10.21236/ada601249.

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Kohrt, Wendy M. Disruption of Calcium Homeostasis during Exercise as a Mediator of Bone Metabolism. Fort Belvoir, VA: Defense Technical Information Center, October 2013. http://dx.doi.org/10.21236/ada593122.

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Kohrt, Wendy M. Disruption of Calcium Homeostasis during Exercise as a Mediator of Bone Metabolism. Fort Belvoir, VA: Defense Technical Information Center, October 2014. http://dx.doi.org/10.21236/ada615544.

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Puigserver, Pere. Maintenance of Glucose Homeostasis through Acetylation of the Metabolic Transcriptional Coactivator PGC-1alpha. Fort Belvoir, VA: Defense Technical Information Center, February 2007. http://dx.doi.org/10.21236/ada467976.

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Puigserver, Pere. Maintenance of Glucose Homeostasis Through Acetylation of the Metabolic Transcriptional Coactivator PGC1-alpha. Fort Belvoir, VA: Defense Technical Information Center, February 2011. http://dx.doi.org/10.21236/ada551301.

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