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Journal articles on the topic 'Home infusion'

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Author: Grafiati

Published: 10 December 2022

Last updated: 28 January 2023

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1

Gill, David Michael, Wendy Burr, Mckenzie Bell, Alisa Thomas, Jenny Simmonds, Megan Mullalley, Libby Petersen, et al. "Barriers to patient-centered oncology care: Pilot study of home infusion of anticancer immunotherapy." Journal of Clinical Oncology 39, no. 28_suppl (October 1, 2021): 36. http://dx.doi.org/10.1200/jco.2020.39.28_suppl.36.

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36 Background: ASCO published a position statement regarding home infusion of anticancer therapy in June 2020. This statement recommends independent research to evaluate the safety and effectiveness of home infusions. Intermountain Healthcare (IM) incorporated this statement into its oncology care with an IRB-approved, prospective single-arm pilot study to determine the safety and feasibility of home administration of checkpoint inhibitor (CPI) immunotherapy with synchronous telemedicine visits. Methods: Patients with cancer receiving treatment at Intermountain Medical Center and Intermountain Cancer Center St. George were screened for enrollment into an IRB-approved, non-randomized pilot study of 20 patients. Eligibility criteria required patients to receive a CPI for an FDA-approved indication, live in Washington County or Salt Lake County, Utah, and have commercial payer coverage of CPI home infusion. Eligible patients were required to receive 2 doses of CPI at an infusion center, and patients who experienced an infusion reaction were excluded from receiving home infusion. Home infusion nurses are trained in oncology, CPIs, and home infusion reaction protocol. During synchronous video visits, infusion nurses are trained to perform the hands-on portions of the physical exam. A financial analysis estimated cost to IM and commercial payers for routine and home CPI infusions. Results: 622 patients were screened, of which 104 were receiving a CPI. 64 patients lived in an eligible county and 19 patients had commercial payer coverage. Of patients on CPIs, 8.7% (9/104) met all eligibility criteria accounting for 1.4% (9/622) of all patients with cancer screened (Table). Financial analysis estimated $829 cost (excluding drug cost) to IM for standard infusion reimbursement compared to $599 for in-home CPI infusions, accounting for savings of $230 per infusion. Majority of cost savings are from elimination of infusion center facilities fee ($495). Analysis includes $269 for home infusion nurse wages. Subsequent analysis for commercial payer SelectHealth estimates $270 reimbursement savings for the payer. Conclusions: Home immunotherapy infusions are estimated to be cost effective for both IM and commercial payers. However, lack of drug coverage and the rural demographics of Utahns with cancer are barriers to home CPI infusions. The pilot study was discontinued per infeasibility stopping criteria.[Table: see text]

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2

GORSKI, LISA A. "Home Infusion Therapy." Home Healthcare Nurse: The Journal for the Home Care and Hospice Professional 27, no. 2 (February 2009): 73–74. http://dx.doi.org/10.1097/01.nhh.0000346307.56757.89.

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3

Gorski, Lisa A., and Laurie Grothman. "Home infusion therapy." Seminars in Oncology Nursing 12, no. 3 (August 1996): 193–201. http://dx.doi.org/10.1016/s0749-2081(96)80037-4.

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4

Cox, Jo Anne, and Linda J. Oakes Westbrook. "Home Infusion Therapy." Journal of Infusion Nursing 28, no. 2 (March 2005): 99–107. http://dx.doi.org/10.1097/00129804-200503000-00003.

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5

Polzien, Gladys. "Home Infusion Therapy." Home Healthcare Nurse: The Journal for the Home Care and Hospice Professional 24, no. 10 (November 2006): 681–84. http://dx.doi.org/10.1097/00004045-200611000-00016.

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6

Perreault, Sarah, Molly Schiffer, Virginia Clinchy-Jarmoszko, Nicole Bocchetta, Lisa Barbarotta, Osama Abdelghany, Francine Foss, Scott Huntington, Stuart Seropian, and Iris Isufi. "Mitigating the risk of COVID-19 exposure by transitioning from clinic-based to home-based immune globulin infusion." American Journal of Health-System Pharmacy 78, no. 12 (February 22, 2021): 1112–17. http://dx.doi.org/10.1093/ajhp/zxab072.

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Abstract Purpose Intravenous immune globulin (IVIG) therapy is used in patients with hypogammaglobulinemia to lower the risk of infections. IVIG and subcutaneous IVIG (SCIG) therapy have been to shown to be safe and effective when administered as clinic-based infusions. Concern from both patients and providers for increased transmission of the coronavirus disease 2019 (COVID-19) virus to immunosuppressed patients with scheduled medical visits and procedures made it necessary for us to reassess our process of how we manage patient care in general and chronic clinic infusions in particular. Here we describe our experience of transitioning patients from clinic-based to home based IVIG and/or SCIG infusions to decrease the risk of COVID-19 exposure. Methods Criteria were developed to identify high-risk immunosuppressed patients who would be appropriate candidates for potential conversion to home based IVIG infusions. Data were collected via chart review, and cost analysis was performed using Medicare Part B reimbursement data. A patient outcome questionnaire was developed for administration through follow-up phone calls. Results From March to May 2020, 45 patients met criteria for home-based infusion, with 27 patients (60%) agreeing to home-based infusion. Posttransition patient outcomes assessment, conducted in 26 patients (96%), demonstrated good patient understanding of the home-based infusion process. No infusion-related complications were reported, and 24 patients (92%) had no concerns about receiving future IVIG and/or SCIG doses at home. No patient tested positive for COVID-19 during the study period. Clinic infusion visits decreased by 26.6 visits per month, resulting in a total of 106 hours of additional available infusion chair time per month and associated cost savings of $12,877. Conclusion Transition of clinic based to home based IVIG/SCIG infusion can be successfully done to decrease potential exposure during a pandemic in a high-risk immunosuppressed population, with no impact on patient satisfaction, adherence, or efficacy. The home-based infusion initiative was associated with a reduction in costs to patients and an increase in available chair time in the infusion clinic.

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7

Doyen, Colleen, Jeff Prosch, Sarah Watkins, and Carla Taylor. "Home infusion or infusion center decision criteria." Molecular Genetics and Metabolism 114, no. 2 (February 2015): S37—S38. http://dx.doi.org/10.1016/j.ymgme.2014.12.068.

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8

Wood, Gillian, Michael Whitby, Patrick Hogan, and Ian Frazer. "FOSCARNET INFUSION AT HOME." Lancet 333, no. 8630 (January 1989): 156. http://dx.doi.org/10.1016/s0140-6736(89)91167-7.

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9

Nathwani, D., S. T. Green, D. J. Goldberg, J. Atkinson, and D. H. Kennedy. "Ganciclovir infusion at home." Journal of Infection 19, no. 3 (November 1989): 294. http://dx.doi.org/10.1016/s0163-4453(89)90989-4.

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10

Westbrook, Kevin W., and Tony Powers. "“The Home Infusion Patient”." Health Marketing Quarterly 16, no. 3 (March 1999): 23–42. http://dx.doi.org/10.1300/j026v16n03_02.

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11

Fields, Bronwyn E., Robin L. Whitney, and Janice F. Bell. "Managing Home Infusion Therapy." AJN, American Journal of Nursing 120, no. 12 (December 2020): 53–59. http://dx.doi.org/10.1097/01.naj.0000724252.22812.a2.

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12

Wehmeyer, Connie, Lisa Berry, and Laurie Bailey. "Home infusions: One center's experience with ERT and self-infusion in the home setting." Molecular Genetics and Metabolism 108, no. 2 (February 2013): S97. http://dx.doi.org/10.1016/j.ymgme.2012.11.265.

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13

Condino, Adria A., Sara Fidanza, and Edward J. Hoffenberg. "A Home Infliximab Infusion Program." Journal of Pediatric Gastroenterology and Nutrition 40, no. 1 (January 2005): 67–69. http://dx.doi.org/10.1097/00005176-200501000-00012.

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14

Walls, Susanne, Miia Rainto, and Ilkka Kantola. "Improving home infusion follow-up." Molecular Genetics and Metabolism 120, no. 1-2 (January 2017): S136. http://dx.doi.org/10.1016/j.ymgme.2016.11.360.

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15

Hendricks, G., C. Lillis, S. Casey, K. Crocker, and G. Devereaux. "Home pain management by infusion." Journal of Pain and Symptom Management 3 (1988): S14. http://dx.doi.org/10.1016/0885-3924(88)90069-3.

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16

Orr, Marsha. "Reflections on Home Infusion Therapy." Nutrition in Clinical Practice 7, no. 6 (December 1992): 255. http://dx.doi.org/10.1177/0115426592007006255.

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17

Williams, Ann. "Catheter Occlusion in Home Infusion." Journal of Infusion Nursing 41, no. 1 (2018): 52–57. http://dx.doi.org/10.1097/nan.0000000000000259.

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18

Poretz, Donald M. "Infusion Center, Office, and Home." Hospital Practice 28, sup2 (March 30, 1993): 40–43. http://dx.doi.org/10.1080/21548331.1993.11442946.

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19

Arnold, Carol M. "Home Infusion: Pharmacy Case Study." Home Health Care Management & Practice 12, no. 1 (December 1999): 20–23. http://dx.doi.org/10.1177/108482239901200108.

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20

Monk-Tutor, Mary R. "The U.S. home infusion market." American Journal of Health-System Pharmacy 55, no. 19 (October 1, 1998): 2019–25. http://dx.doi.org/10.1093/ajhp/55.19.2019.

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21

Leone, Melissa, and L. Rad Dillon. "Catheter Outcomes in Home Infusion." Journal of Infusion Nursing 31, no. 2 (March 2008): 84–91. http://dx.doi.org/10.1097/01.nan.0000313655.65410.4e.

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22

Kivekäs, Eija, Eija Toppinen, Hannu Kokki, Pekka Mäntyselkä, Ulla-Mari Kinnunen, Juhamatti Huusko, and Kaija Saranto. "Infuusiohoidot turvallisesti kotona – selvitys älykkään teknologian mahdollisuuksista." Finnish Journal of eHealth and eWelfare 9, no. 2-3 (May 21, 2017): 184. http://dx.doi.org/10.23996/fjhw.60996.

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The purpose of the research project titled “Safety at Home and in Institutional Care: Utilizing remote monitoring and smart pump -technology in infusion care” was to identify the profile of patients, who require institutional care for infusion therapy for medical and nutrition management, in district hospital area. The digital technology, monitoring, and action models currently use is mapped. The overall purpose is to study the extended implementation of infusion care at home, utilizing smart technology. The data was collected through interviews and statistics. The aim was to explore how home infusion therapy is used, and how willing health care providers are to change current practices. The results showed that infusion therapy was common at outpatient clinics and quite common at home care. Collaboration with home care and emergency care made the infusion therapy possible at patient’s home. The use of smart technology in home care was less usual. The participants were enthusiastic and willing to use smart technology in infusion care and remote monitoring of patients’ status.

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23

Brennan, Veronica. "Home self-infusion of IV immunoglobulin." Nursing Standard 5, no. 47 (August 14, 1991): 37–39. http://dx.doi.org/10.7748/ns.5.47.37.s45.

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24

Molitor, Richard E. "Competition in the Home Infusion Industry." American Journal of Health-System Pharmacy 48, no. 7 (July 1, 1991): 1441–42. http://dx.doi.org/10.1093/ajhp/48.7.1441.

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25

Benson, Judith L. "Best Practices in Home Infusion Therapy." Home Healthcare Nurse 18, no. 5 (May 2000): 341. http://dx.doi.org/10.1097/00004045-200005000-00022.

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26

VRTIS, MARY C., and KRISTIE BURNS. "Evaluating Home Health INTRAVENOUS INFUSION REFERRALS." Home Healthcare Nurse: The Journal for the Home Care and Hospice Professional 28, no. 8 (September 2010): 487–96. http://dx.doi.org/10.1097/nhh.0b013e3181df5dd1.

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27

&NA;. "Evaluating Home Health INTRAVENOUS INFUSION REFERRALS." Home Healthcare Nurse: The Journal for the Home Care and Hospice Professional 28, no. 8 (September 2010): 496–98. http://dx.doi.org/10.1097/nhh.0b013e3181e2caef.

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28

GRAVES, DANA BELKNAP. "Home Infusion Therapy MEETING A NEED." Nursing Management (Springhouse) 26, no. 8 (August 1995): 33. http://dx.doi.org/10.1097/00006247-199508000-00012.

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29

Michela, Nancy J. "High-tech home care infusion therapy." Geriatric Nursing 16, no. 5 (September 1995): 249–50. http://dx.doi.org/10.1016/s0197-4572(05)80177-6.

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30

Matthews, Lyle E. "PREPARING YOUR PATIENT FOR HOME INFUSION." Nursing 24, no. 10 (October 1994): 28–29. http://dx.doi.org/10.1097/00152193-199410000-00013.

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31

Pugliese, Gina, and Martin S. Favero. "HCV Transmission During Home Infusion Therapy." Infection Control & Hospital Epidemiology 18, no. 9 (September 1997): 669–70. http://dx.doi.org/10.1017/s019594170009247x.

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32

Romeo, Cathy C., and Patsy Jones. "Home Infusion Therapies for Obstetric Patients." Journal of Obstetric, Gynecologic & Neonatal Nursing 23, no. 8 (October 1994): 675–81. http://dx.doi.org/10.1111/j.1552-6909.1994.tb01937.x.

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33

Chapel, H., and V. Brennan. "Self-infusion with immunoglobulin at home." Journal of Clinical Pathology 44, no. 5 (May 1, 1991): 358–59. http://dx.doi.org/10.1136/jcp.44.5.358.

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34

Condino, A. A., S. Fidanza, and E. J. Hoffenberg. "P0597 A HOME INFLIXIMAB INFUSION PROGRAM." Journal of Pediatric Gastroenterology and Nutrition 39, Supplement 1 (June 2004): S283—S284. http://dx.doi.org/10.1097/00005176-200406001-00721.

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35

Wilder, Gloria Lee. "Medication Safety in Home Infusion Care." Journal of Infusion Nursing 26, no. 5 (September 2003): 311–18. http://dx.doi.org/10.1097/00129804-200309000-00007.

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36

Webb, Joshua, and Doohee Lee. "Medicare Home Infusion Therapy Reimbursement Gap." Home Health Care Services Quarterly 31, no. 4 (December 2012): 302–16. http://dx.doi.org/10.1080/01621424.2012.734741.

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37

&NA;. "Pocket Guide to Home Infusion Therapy." Home Healthcare Nurse: The Journal for the Home Care and Hospice Professional 23, no. 6 (June 2005): 404. http://dx.doi.org/10.1097/00004045-200506000-00016.

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38

Power, Elaine J. "Home Drug Infusion Therapy Under Medicare." JAMA: The Journal of the American Medical Association 270, no. 4 (July 28, 1993): 427. http://dx.doi.org/10.1001/jama.1993.03510040027008.

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39

Gupta, Arjun, Mary C. Hon, Neil Keshvani, Eileen M. Marley, David H. Johnson, Navid Sadeghi, and Hsiao Ching Li. "Creating value: Institution of outpatient infusional EPOCH-based chemotherapy at a safety-net hospital." Journal of Clinical Oncology 36, no. 30_suppl (October 20, 2018): 128. http://dx.doi.org/10.1200/jco.2018.36.30_suppl.128.

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128 Background: EPOCH-based chemotherapy regimens are traditionally administered inpatient because they include a continuous 96-hour infusion. These admissions are costly, and disruptive to patients’ lives. We transitioned EPOCH-based chemotherapy regimens to an ambulatory infusion model at our safety-net hospital (Parkland Health and Hospital System, Dallas, TX), where patients visit the infusion center daily for 5 days. Methods: Guidelines for chemotherapy administration and educational materials were developed through a multidisciplinary collaboration with physicians, nursing, and pharmacy. Data were collected through chart review and the finance department. Project costs included purchase of portable infusion pumps and increasing outpatient infusion clinic capacity. Patient satisfaction with home infusions compared to hospitalization was measured on a Likert-type scale via direct-to-patient survey. Results: From 1/30/2017 through 1/30/2018, a total of 87 cycles of EPOCH-based chemotherapy were administered to 23 unique patients. 61 (70%) of these cycles were administered in the outpatient setting to 18 unique patients. There was a 58% reduction in drug costs in the outpatient setting due to lower drug acquisition cost. An estimated 336 days of hospital stay were avoided. There were no inappropriate prophylactic antimicrobial prescriptions and daily blood draws in the outpatient setting. 88% of survey responders reported > 3 (scale, 1 to 5) on a Likert-type scale for both overall experience with home infusions, and likelihood they would use home infusions again. No chemotherapy spills or extravasation occurred; 1 cycle was complicated by pump failure where chemotherapy was given at a slower rate than intended. Conclusions: Multiday EPOCH-based regimens were successfully and safely administered in an ambulatory setting at our safety net urban hospital. Patients reported satisfaction with the experience, and received less unnecessary interventions in the outpatient setting. Significant cost savings from avoided hospitalization and decreased drug acquisition cost were demonstrated.

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40

O'Leary, Shirley, Jill Beavin, Cynthia Bishop, Lisa Capolino, Elida Greinel, and Elizabeth Hudson. "Practical Guidelines for Administering Natalizumab: A Nursing Perspective." International Journal of MS Care 9, no. 1 (January 1, 2007): 1–8. http://dx.doi.org/10.7224/1537-2073-9.1.1.

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Natalizumab (Tysabri) was recently reapproved in the United States and the European Union for the treatment of relapsing forms of multiple sclerosis (MS). Natalizumab is administered once every 4 weeks as a 300-mg intravenous infusion given over 1 hour, followed by 1 hour of monitoring. Guidelines for preparing and administering natalizumab infusions are reviewed. In addition, patient monitoring parameters and guidelines for identification and management of infusion-related reactions are discussed. Natalizumab may be administered in various settings, including the hospital, physician's office, and infusion center. Special considerations for these settings are also discussed. Currently, home care is not a consideration for natalizumab infusion.

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41

Laskey, A. L., C. Dyer, and J. D. Tobias. "Venous Air Embolism During Home Infusion Therapy." PEDIATRICS 109, no. 1 (January 1, 2002): e15-e15. http://dx.doi.org/10.1542/peds.109.1.e15.

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42

Weinstein, Sharon M. "A Coordinated Approach to Home Infusion care." Home Healthcare Nurse: The Journal for the Home Care and Hospice Professional 11, no. 1 (January 1993): 15–20. http://dx.doi.org/10.1097/00004045-199301000-00004.

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43

Benson, Judith L. "Home Infusion: Current Status and Future Trends." Home Healthcare Nurse: The Journal for the Home Care and Hospice Professional 14, no. 3 (March 1996): 207. http://dx.doi.org/10.1097/00004045-199603000-00012.

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44

Martel, Denise. "Infusion Therapy in the Home Care Setting." Home Healthcare Nurse 30, no. 9 (October 2012): 506–14. http://dx.doi.org/10.1097/nhh.0b013e31826a679c.

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45

Millward, Edward T. "Impact of Medicare Cuts on Home Infusion." Home Health Care Management & Practice 13, no. 4 (June 2001): 280–82. http://dx.doi.org/10.1177/108482230101300407.

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46

Birnbaum, Howard G., and Ming Tang. "The Home Infusion Therapy/Relative Benefit Index." Medical Care 36, no. 5 (May 1998): 757–65. http://dx.doi.org/10.1097/00005650-199805000-00016.

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47

Boulétreau, P. "The optimal infusion line for home parenteralnutrition." Clinical Nutrition 14 (June 1995): 56–58. http://dx.doi.org/10.1016/s0261-5614(95)80285-1.

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48

Balinsky, Warren, and Arthur Mollin. "Home Drug Infusion Therapy: A Literature Update." International Journal of Technology Assessment in Health Care 14, no. 3 (1998): 535–43. http://dx.doi.org/10.1017/s026646230001151x.

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AbstractThis paper is a literature review and update of home drug infusion therapy (HDIT) in the United States. It concentrates on cost-effectiveness studies of parenteral antibiotic therapy administered in an outpatient setting. This update is timely because Medicare and other payors are under the pressure of cost containment with respect to this modality. Additionally, managed care is redefining reimbursement programs, which will affect HDIT in the future.

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49

Rich, Darryl. "Physicians, pharmacists, and home infusion antibiotic therapy." American Journal of Medicine 97, no. 2 (August 1994): 3–8. http://dx.doi.org/10.1016/0002-9343(94)90281-x.

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50

Loader, Jill, Graham Sewell, and Shivaun Gammie. "Survey of home infusion care in England." American Journal of Health-System Pharmacy 57, no. 8 (April 15, 2000): 763–66. http://dx.doi.org/10.1093/ajhp/57.8.763.

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