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Author: Grafiati
Published: 30 May 2022
Last updated: 31 May 2022

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1

Swerdlow, David. Small holes in the universe. Cincinnati, OH: WordTech Editions, 2003.

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2

Grace, Patricia. Small holes in the silence: Short stories. Auckland, N.Z: Penguin Books, 2006.

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3

Tuwhare, Hone. Small holes in the silence: Collected works. Auckland, N.Z: Random House New Zealand, 2011.

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4

Meitzner, Laura S. Amaranth to zai holes: Ideas for growing food under difficult conditions. North Fort Myers, Fla: ECHO, 1996.

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5

Tang, K. Linda. The effect of small calibration sample sizes on TOEFL IRT-based equating. Princeton, N.J: Educational Testing Service, 1993.

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6

Maylor, Harvey. The application of quality assurance to advanced manufacturing systems for small batch sizes. Uxbridge: BrunelUniversity, 1991.

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7

Porter, Robert D. How to make a super sensitive micro drill press to drill very small holes. [United States?: s.n.], 2007.

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8

Porter, Robert D. How to make a super sensitive micro drill press to drill very small holes. [United States?: s.n.], 2007.

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9

Champlain, Andre F. De. Assessing the dimensionality of simulated LSAT item response matrices with small sample sizes and short test lengths. Newtown, PA: Law School Admission Council, 1999.

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10

Small homes: The right size. Shelter Publications, 2017.

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11

Big And Small (Sizes). Heinemann, 2005.

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12

Tuwhare, Hone. Small Holes in the Silence. Random House New Zealand, 2016.

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13

Small Crack Growth at Pin Loaded Holes. Storming Media, 2003.

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14

Melmon, Deborah. Albert's BIGGER Than Big Idea : Comparing Sizes: Big/Small. Boyds Mills & Kane, 2014.

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15

Melmon, Deborah. Albert's BIGGER Than Big Idea : Comparing Sizes: Big /Small. Boyds Mills & Kane, 2018.

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16

Melmon, Deborah. Albert's BIGGER Than Big Idea : Comparing Sizes: Big/Small. Boyds Mills & Kane, 2014.

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17

How big is big and how small is small: The sizes of everything and why. 2013.

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18

DeLong, Lois Anne, and Barbara Anne Antonucci. No Stable Too Small: Fifteen Christmas Plays for Churches of All Sizes. CSS Publishing Company, 2006.

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19

Designer crochet: 32 patterns to elevate your style, sizes small to 5X. 2015.

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20

Cardigans With A Conscience 6 Knit Designs In Sizes Small To 3x. Leisure Arts, 2010.

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21

D, Meier Paul, ed. Filling the holes in our souls: Caring groups that build lasting relationships. Chicago: Moody Press, 1992.

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22

Machines Large and Small (Learning Languages). Rourke Publishing, 2007.

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23

Blank, Beverlee. DAMN I CAN't Remember: Password Notebook Small Sizes 104 Page Size 6x9 Inches Matte Cover Design White Paper Sheet ~ Note - Funny # Security Very Fast Prints. Independently Published, 2020.

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24

Blank, Mila. Shit I Can't Remember: Password Notebook Small Sizes 100 Pages Size 6x9 Inch Glossy Cover Design White Paper Sheet ~ Print - Password # Tracker Very Fast Print. Independently Published, 2020.

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25

Scott, Frank Jesup. Art of Beautifying Suburban Home Grounds of Small Extent: The Advantages of Suburban Homes over City or Country Homes; the Comfort and Economy of Neighboring Improvements; the Choice and Treatment of Building Sites; and the Best Modes of Laying Out, P. HardPress, 2020.

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26

Tizuko, Kettmuno. Funny Beauty Comes in All Shapes and Sizes Large, Small T-Shirt Notebook: 120 Pages - Size 6x9 Inch - Use for Doodle, Note, Plan, Music Tab, Diary... ... ... ... ... ... ... ... ... ... ... ... ... . Independently Published, 2020.

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27

LogBook, Doria. Log Password Book: Password Notebook Small Sizes 108 Pages Matte Cover Design White Paper Sheet Size 6 X 9 Inches ~ Removable - Personal # Personal Very Fast Print. Independently Published, 2020.

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28

Powell, Roger A., Stephen Ellwood, Roland Kays, and Tiit Maran. Stink or swim: techniques to meet the challenges for the study and conservation of small critters that hide, swim, or climb, and may otherwise make themselves unpleasant. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198759805.003.0008.

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The study of musteloids requires different perspectives and techniques than those needed for most mammals. Musteloids are generally small yet travel long distances and many live or forage underground or under water, limiting the use of telemetry and direct observation. Some are arboreal and nocturnal, facilitating telemetry but limiting observation, trapping, and many non-invasive techniques. Large sexual size dimorphism arguably doubles sample sizes for many research questions. Many musteloids defend themselves by expelling noxious chemicals. This obscure group does not attract funding, even when endangered, further reducing rate of knowledge gain. Nonetheless, passive and active radio frequency identification tags, magnetic-inductance tracking, accelerometers, mini-biologgers and some GPS tags are tiny enough for use with small musteloids. Environmental DNA can document presence of animals rarely seen. These technologies, coupled with creative research design that is well-grounded on the scientific method, form a multi-dimensional approach for advancing our understanding of these charismatic minifauna.
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29

Szeftel, Jérémie, and Sergiu Klainerman. Global Nonlinear Stability of Schwarzschild Spacetime under Polarized Perturbations. Princeton University Press, 2020. http://dx.doi.org/10.23943/princeton/9780691212425.001.0001.

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One of the major outstanding questions about black holes is whether they remain stable when subject to small perturbations. An affirmative answer to this question would provide strong theoretical support for the physical reality of black holes. This book takes an important step toward solving the fundamental black hole stability problem in general relativity by establishing the stability of nonrotating black holes — or Schwarzschild spacetimes — under so-called polarized perturbations. This restriction ensures that the final state of evolution is itself a Schwarzschild space. Building on the remarkable advances made in the past fifteen years in establishing quantitative linear stability, the book introduces a series of new ideas to deal with the strongly nonlinear, covariant features of the Einstein equations. Most preeminent among them is the general covariant modulation (GCM) procedure that allows them to determine the center of mass frame and the mass of the final black hole state. Essential reading for mathematicians and physicists alike, the book introduces a rich theoretical framework relevant to situations such as the full setting of the Kerr stability conjecture.
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30

Bernstein, Sara, and Tyron Goldschmidt, eds. Non-Being. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780198846222.001.0001.

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We are surrounded by things that exist, like chairs, tables, phones, and people. But we are also surrounded by things that don’t exist, like holes, shadows, omissions, and negative properties. We read stories of nonexistent unicorns and magical creatures. We reason about scenarios that don’t exist, from the small (‘what if I’d have studied an hour longer?’) to the large (‘what if World War II hadn’t occurred?’). We refer to nonexistents (‘that paper doesn’t exist yet’). And we hold people morally responsible for things that they don’t do (‘you should have rescued the rabbit!’). Nonexistence is ubiquitous, yet mysterious. This volume of new essays covers some of the trickiest questions about non-being and nonexistence—from Could have been nothing at all? to What are holes?—alongside answers from diverse philosophical traditions. The essays explore analytic, continental, Buddhist and Jewish philosophical perspectives, and range from metaphysics to ethics, from philosophy of science to philosophy of language, and beyond.
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31

Verschuur, Gerrit L. Impact! Oxford University Press, 1996. http://dx.doi.org/10.1093/oso/9780195101058.001.0001.

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Most scientists now agree that some sixty-five million years ago, an immense comet slammed into the Yucatan, detonating a blast twenty million times more powerful than the largest hydrogen bomb, punching a hole ten miles deep in the earth. Trillions of tons of rock were vaporized and launched into the atmosphere. For a thousand miles in all directions, vegetation burst into flames. There were tremendous blast waves, searing winds, showers of molten matter from the sky, earthquakes, and a terrible darkness that cut out sunlight for a year, enveloping the planet in freezing cold. Thousands of species of plants and animals were obliterated, including the dinosaurs, some of which may have become extinct in a matter of hours. In Impact, Gerrit L. Verschuur offers an eye-opening look at such catastrophic collisions with our planet. Perhaps more important, he paints an unsettling portrait of the possibility of new collisions with earth, exploring potential threats to our planet and describing what scientists are doing right now to prepare for this awful possibility. Every day something from space hits our planet, Verschuur reveals. In fact, about 10,000 tons of space debris fall to earth every year, mostly in meteoric form. The author recounts spectacular recent sightings, such as over Allende, Mexico, in 1969, when a fireball showered the region with four tons of fragments, and the twenty-six pound meteor that went through the trunk of a red Chevy Malibu in Peekskill, New York, in 1992 (the meteor was subsequently sold for $69,000 and the car itself fetched $10,000). But meteors are not the greatest threat to life on earth, the author points out. The major threats are asteroids and comets. The reader discovers that astronomers have located some 350 NEAs ("Near Earth Asteroids"), objects whose orbits cross the orbit of the earth, the largest of which are 1627 Ivar (6 kilometers wide) and 1580 Betula (8 kilometers). Indeed, we learn that in 1989, a bus-sized asteroid called Asclepius missed our planet by 650,000 kilometers (a mere six hours), and that in 1994 a sixty-foot object passed within 180,000 kilometers, half the distance to the moon. Comets, of course, are even more deadly. Verschuur provides a gripping description of the small comet that exploded in the atmosphere above the Tunguska River valley in Siberia, in 1908, in a blinding flash visible for several thousand miles (every tree within sixty miles of ground zero was flattened). He discusses Comet Swift-Tuttle--"the most dangerous object in the solar system"--a comet far larger than the one that killed off the dinosaurs, due to pass through earth's orbit in the year 2126. And he recounts the collision of Comet Shoemaker-Levy 9 with Jupiter in 1994, as some twenty cometary fragments struck the giant planet over the course of several days, casting titanic plumes out into space (when Fragment G hit, it outshone the planet on the infrared band, and left a dark area at the impact site larger than the Great Red Spot). In addition, the author describes the efforts of Spacewatch and other groups to locate NEAs, and evaluates the idea that comet and asteroid impacts have been an underrated factor in the evolution of life on earth. Astronomer Herbert Howe observed in 1897: "While there are not definite data to reason from, it is believed that an encounter with the nucleus of one of the largest comets is not to be desired." As Verschuur shows in Impact, we now have substantial data with which to support Howe's tongue-in-cheek remark. Whether discussing monumental tsunamis or the innumerable comets in the Solar System, this book will enthrall anyone curious about outer space, remarkable natural phenomenon, or the future of the planet earth.
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32

Jiménez, Catalina, Julen Requejo, Miguel Foces, Masato Okumura, Marco Stampini, and Ana Castillo. Silver Economy: A Mapping of Actors and Trends in Latin America and the Caribbean. Inter-American Development Bank, 2021. http://dx.doi.org/10.18235/0003237.

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Latin America and the Caribbean, unlike other regions, is still quite young demographically: people over age 60 make up around 11% of the total population. However, the region is expected to experience the fastest rate of population aging in the world over the coming decades. This projected growth of the elderly population raises challenges related to pensions, health, and long-term care. At the same time, it opens up numerous business opportunities in different sectorshousing, tourism, care, and transportation, for examplethat could generate millions of new jobs. These opportunities are termed the “silver economy,” which has the potential to be one of the drivers of post-pandemic economic recovery. Importantly, women play key roles in many areas of this market, as noted in the first report published by the IDB on this subject (Okumura et al., 2020). This report maps the actors whose products or services are intended for older people and examines silver economy trends in the region by sector: health, long-term care, finance, housing, transportation, job market, education, entertainment, and digitization. The mapping identified 245 actors whose products or services are intended for older people, and it yielded three main findings. The first is that the majority of the actors (40%) operate in the health and care sectors. The prevalence of these sectors could be due to the fact that they are made up of many small players, and it could also suggest a still limited role of older people in active consumption, investment, and the job market in the region. The second finding is that 90% of the silver economy actors identified by the study operate exclusively in their countries of origin, and that Mexico has the most actors (47), followed by the Southern Cone countriesBrazil, Chile, and Argentinawhich have the regions highest rates of population aging. The third finding is that private investment dominates the silver economy ecosystem, as nearly 3 out of every 4 actors offering services to the elderly population are for-profit enterprises. The sectors and markets of the silver economy differ in size and degree of maturity. For example, the long-term care sector, which includes residential care settings, is the oldest and has the largest number of actors, while sectors like digital, home automation, and cohousing are still emerging. Across all sectors, however, there are innovative initiatives that hold great potential for growth. This report examines the main development trends of the silver economy in the region and presents examples of initiatives that are already underway. The health sector has a wealth of initiatives designed to make managing chronic diseases easier and to prevent and reduce the impact of functional limitations through practices that encourage active aging. In the area of long term careone of the most powerful drivers of job creationinitiatives to train human resources and offer home care services are flourishing. The financial sector is beginning to meet a wide range of demands from older people by offering unique services such as remittances or property management, in addition to more traditional pensions, savings, and investment services. The housing sector is adapting rapidly to the changes resulting from population aging. This shift can be seen, for example, in developments in the area of cohousing or collaborative housing, and in the rise of smart homes, which are emerging as potential solutions. In the area of transportation, specific solutions are being developed to meet the unique mobility needs of older people, whose economic and social participation is on the rise. The job market offers older people opportunities to continue contributing to society, either by sharing their experience or by earning income. The education sector is developing solutions that promote active aging and the ongoing participation of older people in the regions economic and social life. Entertainment services for older people are expanding, with the emergence of multiple online services. Lastly, digitization is a cross-cutting and fundamental challenge for the silver economy, and various initiatives in the region that directly address this issue were identified. Additionally, in several sectors we identified actors with a clear focus on gender, and these primarily provide support to women. Of a total of 245 actors identified by the mapping exercise, we take a closer look at 11 different stories of the development of the silver economy in the region. The featured organizations are RAFAM Internacional (Argentina), TeleDx (Chile), Bonanza Asistencia (Costa Rica), NudaProp (Uruguay), Contraticos (Costa Rica), Maturi (Brazil), Someone Somewhere (Mexico), CONAPE (Dominican Republic), Fundación Saldarriaga Concha (Colombia), Plan Ibirapitá (Uruguay), and Canitas (Mexico). These organizations were chosen based on criteria such as how innovative their business models are, the current size and growth potential of their initiatives, and their impact on society. This study is a first step towards mapping the silver economy in Latin America and the Caribbean, and the hope is to broaden the scope of this mapping exercise through future research and through the creation of a community of actors to promote the regional integration of initiatives in this field.
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33

Anderson, Michael, and Corinne Roughley. The First Scottish Fertility Decline. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198805830.003.0014.

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The marked variations in the distribution of family sizes over time are further explored, as also are the major variations between women married to fathers in different occupations. The significance of very small families in fertility constraint is explored. The role in Scotland of possible methods of family limitation at different dates is examined, in the context of ongoing historical debates about when, if ever, most couples began consciously to ‘plan’ the size of their families, and at what point in their marriages they may have done so. In the same context, Scottish evidence is reviewed on the possible reasons for the timing of the onset of fertility decline and its spread through to the 1930s.
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34

Size matters: measuring the effects of inequality and growth shocks. UNU-WIDER, 2020. http://dx.doi.org/10.35188/unu-wider/2020/934-1.

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Understanding the relationship between income inequality and economic growth is of utmost importance to economists and social scientists. In this paper we use a Bayesian structural vector autoregression approach to estimate the relationship between inequality and growth via growth and inequality shocks for two large economies, China and the USA, for the years 1979–2018. We find that a growth shock is inequality-increasing, and an inequality shock is growth-reducing. We also find, however, that the sizes of the effects of these shocks are very small, accounting for under 2 per cent of the variance for both countries. Finally, we also find that the effects of the shocks dissipate within ten years, suggesting that the effects of these shocks are a short-term phenomenon.
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35

Faddegon, Stephen, Ephrem O. Olweny, and Jeffrey A. Cadeddu. Ablative technologies for renal cancer. Edited by James W. F. Catto. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199659579.003.0087.

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Nearly two-thirds of newly detected renal masses are clinical stage 1, with T1a tumours accounting for 60% of the newly detected stage 1 tumours. Guideline panels convened by the American Urological Association and the European Association of Urology recommend nephron-sparing surgery as the gold standard treatment for small renal masses, with active surveillance and thermal ablation recommended as alternative strategies in select patients. However, there is a dearth of studies directly comparing outcomes for energy-based ablation to those for traditional surgical treatments for small renal masses, and future prospective randomized trials will be invaluable in this regard. Ongoing research in renal tumour ablation targets several areas, including but not limited to achieving larger ablation sizes, decreasing morbidity, and development of novel technologies for renal tumour ablation.
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36

Bliwise, Donald L., and Michael K. Scullin. Sleep and cognition. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198778240.003.0004.

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Possible associations between sleep and cognition are provocative across different domains and hold the promise of prevention or reversibility. A vast array of studies has been reported. Evidence is suggestive but hardly definitive. We provide an overview of this literature, adopting the framework of Hill’s perspective on epidemiological causation. With rare exception, formal meta-analyses have yet to appear. Apparent consistency of findings suggests relationships, but the diversity of findings involving specific components of cognitive function raises interpretative caution. Large effect sizes have been noted, but small-to-moderate effects predominate. Natural history data are similarly enticing, and studies of biological plausibility and gradient indicate likely neurobiological substrates. Perhaps the ultimate population-health criterion, demonstration of reversibility of impairment, remains elusive at best. This area offers an exciting topic for future work.
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37

Koen, N., T. Amos, J. Ipser, and D. Stein. Antidepressants in Post-Traumatic Stress Disorder. Edited by Charles B. Nemeroff and Charles R. Marmar. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190259440.003.0034.

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This chapter discusses the use of antidepressants in treating symptoms of posttraumatic stress disorder (PTSD). Tricyclic antidepressants were the first psychotropic agents to be studied systematically and rigorously for the treatment of PTSD. While early studies focused both on the tricyclics and monoamine oxidase inhibitors (MAOIs), more recent work has centered on the selective serotonin reuptake inhibitors (SSRIs); and paroxetine and sertraline are currently approved by the U.S. Food and Drug Administration (FDA) for use in this disorder. However, given the relatively small effect sizes in SSRI trials of PTSD, there is a need for ongoing psychopharmacological research to understand underlying mechanisms of antidepressant efficacy and to optimize response to pharmacotherapy. Further data on pediatric PTSD and on medication prophylaxis are needed before routine antidepressant treatment can be endorsed in these contexts.
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38

Lambert, Philip. Loyalties. University of Illinois Press, 2017. http://dx.doi.org/10.5406/illinois/9780252037603.003.0004.

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This chapter studies Wilder's music in the 1960s. Continuing to follow trends he had begun at the end of the preceding decade, he wrote volumes of concert music for groups of all sizes in the 1960s, for wind ensembles and chamber orchestras and small groups and soloists with piano. He also wrote piano music, dramatic music of diverse kinds, and a handful of new songs, following traditional popular or art-song models. Also extending earlier trends, Wilder's loyalties to his artistic and ideological roots found musical expression through the efforts of loyal friends. As his travels and residencies and friendships multiplied, so did his catalog of original compositions perfectly suited for a faculty ensemble or senior recital or informal gathering in a college practice room or dormitory basement.
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39

Fitzpatrick, Matthew C., and Aaron M. Ellison. Estimating the exposure of carnivorous plants to rapid climatic change. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198779841.003.0028.

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Climatic change likely will exacerbate current threats to carnivorous plants. However, estimating the severity of climatic change is challenged by the unique ecology of carnivorous plants, including habitat specialization, dispersal limitation, small ranges, and small population sizes. We discuss and apply methods for modeling species distributions to overcome these challenges and quantify the vulnerability of carnivorous plants to rapid climatic change. Results suggest that climatic change will reduce habitat suitability for most carnivorous plants. Models also project increases in habitat suitability for many species, but the extent to which these increases may offset habitat losses will depend on whether individuals can disperse to and establish in newly suitable habitats outside of their current distribution. Reducing existing stressors and protecting habitats where numerous carnivorous plant species occur may ameliorate impacts of climatic change on this unique group of plants.
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40

Buitelaar, Jan K., Nanda Rommelse, Verena Ly, and Julia J. Rucklidge. Nutritional intervention for ADHD. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198739258.003.0040.

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This chapter discusses four dietary interventions (exclusion of artificial colours and preservatives; restrictive elimination diets/oligoantigenic diets; supplementation with omega-3 fatty acids; and supplementation with micronutrients) and their clinical relevance for ADHD. The evidence base for exclusion of artificial colours and preservatives has many gaps. Effectiveness of the elimination phase of elimination diets has been demonstrated in several randomized clinical trials and about one-third of the children with ADHD show an excellent response. Data on maintenance of effect in the longer term, however, are lacking. Supplementation of free fatty acids was associated with a small but reliable reduction of ADHD symptoms, but the clinical relevance is unclear. The trials using a broad spectrum of micronutrients show promise but suffered from small sample sizes, lack of controls, varied sampling procedures and inclusion criteria, and multiple assessment methods, and need confirmation.
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41

Holdt, Lesca M., and Daniel Teupser. Genetic background of atherosclerosis and its risk factors. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199656653.003.0002.

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This chapter is concerned with how atherosclerosis risk is modulated by a complex interplay between genetic and environmental risk factors. The contribution of genetics to the variability of atherosclerosis risk is estimated as 50%. Recent genome-wide association studies have led to the identification of over 50 gene variants which modulate atherogenesis. Risk factors for atherosclerosis are also partly genetically determined and some of the variants which play a role in atherogenesis overlap with those modulating its risk factors. However, the current relevance of these findings for clinical practice is limited, mainly due to the small effect sizes of identified risk variants with insufficient discriminatory power, and a large portion of the genetic contribution to atherosclerosis is still unknown. The major promise therefore lies in understanding the pathophysiology of newly identified genes with the perspective of novel therapeutic approaches.
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42

Ravindran, Arun V., and Tricia L. da Silva. The role of complementary and alternative therapies for the management of bipolar disorder. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198748625.003.0029.

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Complementary and alternative medicine (CAM) therapies are a group of diverse medical and health systems, practices, and products not currently considered to be part of conventional medicine. These therapies have growing popularity and it is suggested that more than a third of patients with bipolar disorder (BD) use some form of CAM therapy. Although there are several forms of CAM therapies, including physical therapies, nutraceuticals, herbal remedies, and mindfulness-based interventions, reports in BD are few in number and often of poor quality. Sleep deprivation has the strongest evidence for benefit as an augmentation therapy in bipolar depression. There is promising evidence for other CAM therapies, including exercise, bright light therapy, omega-3 fatty acids, N-acetylcysteine, and the traditional Chinese medicine formulation, Free and Easy Wanderer Plus. However, limitations such as small number of studies, small sample sizes, few randomized investigations, and contradictory findings currently preclude definitive recommendations.
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43

Joyce, Rosemary A. Breaking Bodies and Biographies. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190614812.003.0002.

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Figurines made in Honduras between 900 and 400 BCE established connections among persons through fragmentation, partibility, and enchainment. These figurines were made in two distinct sizes, both miniaturized. Their miniaturization requires concentrated attention to worked surfaces that reveal, on close examination, fine detail, requiring handling and rotation. Larger figurines are rarely recovered intact, often forming assemblages of heads or bodies that imply the dispersal of a partible body. Smaller figurines pierced for suspension as pendants normally are completely intact. They differ in their range of subjects, including both animals and the human subjects typical of the larger figurines. The small figurine pendants were likely to have been objects worn as part of costume. They thus can also be seen as fragmented, separated from the human bodies of which they once formed prosthetic extensions. Together, the larger and smaller figurines create social relations through their miniaturization, focusing attention, and partibility, creating connections.
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44

Hilbert, Anja, Lisa Opitz, and Martina de Zwaan. Internet-Based Interventions for Eating Disorders. Edited by W. Stewart Agras and Athena Robinson. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780190620998.013.28.

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Evidence demonstrating the efficacy of treatment and prevention programs for eating disorders is accruing. However, the common face-to-face delivery of these interventions has a number of limitations, including high cost and limited accessibility. E-mental health, referring to the use of information and communication technology—particularly the Internet—in interventions for mental health disorders, has the potential to overcome these barriers and enhance the treatment and prevention of eating disorders. To date, the limited number of evaluations have documented small to moderate effect sizes in the improvement of eating disorder symptomatology through Internet-based treatment and prevention. Beyond efficacy, major questions remain regarding content, structure, and modes of delivery of Internet-based interventions; suitable diagnostic tools and safety measures; and cost-effectiveness, dissemination, and implications for public health programming. These aspects deserve attention in future research before widely recommending Internet-based interventions for eating disorders.
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45

Edele, Mark. Scenarios. Oxford University Press, 2017. http://dx.doi.org/10.1093/oso/9780198798156.003.0004.

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This chapter discusses the various ways in which defectors came across the front line. Scenarios varied. Some defectors came as part of organized desertions of entire units; more came in small groups; and about just as many came alone. The front line could be overcome simply by letting it pass, a particularly viable option in 1941, but also possible later in the war; others exploited holes in the front, used planes or tanks to get across, or absconded after having been sent across the line in an attack or a commando operation. Often, defection was a violent process, which required sometimes deadly force against superiors or compadres. The chapter describes these scenarios and puts the moment of defection into a larger framework of the wartime trajectories of men who ended up surrendering.
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46

Yousefshahi, Fardin, Giuliano Michelagnoli, and Juan Francisco Asenjo. Ketamine Use and Opioid-Tolerant Cancer Patients. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190271787.003.0031.

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Pain occurs in up to 70% of cancer patients and it can be challenging to manage. The standard for analgesic therapy is the World Health Organization ladder; however, up to 25% of patients don’t reach a level of comfort using this approach. Ketamine has been recognized as an excellent adjuvant for cancer pain treatment, especially when other analgesics have failed. Some randomized clinical trials have confirmed ketamine’s efficacy in refractory cancer pain, but most had small sample sizes and low power. Some publications have confirmed the beneficial effect of oral, intranasal, subcutaneous, or intravenous ketamine in treatment of refractory chronic cancer pain, while others are less conclusive. While ketamine is rapidly gaining ground as an adjuvant in treating pain in patients with cancers refractory to conventional therapy and/or patients with opioid tolerance, care should be taken to identify patients with ketamine contraindications in order to offer the greatest benefit with the lowest risk of side effects.
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47

Newman, Mark. The configuration model. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198805090.003.0012.

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A discussion of the most fundamental of network models, the configuration model, which is a random graph model of a network with a specified degree sequence. Following a definition of the model a number of basic properties are derived, including the probability of an edge, the expected number of multiedges, the excess degree distribution, the friendship paradox, and the clustering coefficient. This is followed by derivations of some more advanced properties including the condition for the existence of a giant component, the size of the giant component, the average size of a small component, and the expected diameter. Generating function methods for network models are also introduced and used to perform some more advanced calculations, such as the calculation of the distribution of the number of second neighbors of a node and the complete distribution of sizes of small components. The chapter ends with a brief discussion of extensions of the configuration model to directed networks, bipartite networks, networks with degree correlations, networks with high clustering, and networks with community structure, among other possibilities.
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48

Bennell, Kim L., Ans Van Ginckel, Fiona Dobson, and Rana S. Hinman. Exercise for the person with osteoarthritis. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199668847.003.0022.

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Because of its beneficial effects on pain and physical dysfunction commonly reported by afflicted individuals, all clinical guidelines of osteoarthritis (OA) advocate exercise therapy as a vital component of conservative management strategies. Although the optimal exercise modalities in terms of dosage, exercise type, or delivery mode are not yet known, clinical benefits can be achieved with a wide range of exercise types. While treatment effect sizes may be considered small to moderate, they are similar to those of common analgesic drugs or oral non-steroidal anti-inflammatories but seem to elicit fewer side effects. To achieve optimal treatment outcomes, programme parameters should be individualized to the patient’s clinical characteristics and preferences. Where validated instruments could assist the clinician in monitoring the progress of an exercise intervention programme, adherence to exercise in the longer term is a prerequisite to maintain symptom relief over time. Whereas the current body of evidence mainly comprises clinical trials in people with knee OA, future studies should continue to address efficacy and safety of exercise therapy in individuals suffering from hand or hip OA and should further determine its ability to postpone the need for costly arthroplasty surgery.
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49

Aveyard, Bob. Surfactants. Oxford University Press, 2019. http://dx.doi.org/10.1093/oso/9780198828600.001.0001.

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Characteristically, surfactants in aqueous solution adsorb at interfaces and form aggregates (micelles of various shapes and sizes, microemulsion droplets, and lyotropic liquid crystalline phases). This book is about the behaviour of surfactants in solution, at interfaces, and in colloidal dispersions. Adsorption at liquid/fluid and solid/liquid interfaces, and ways of characterizing the adsorbed surfactant films, are explained. Surfactant aggregation in systems containing only an aqueous phase and in systems with comparable volumes of water and nonpolar oil are each considered. In the latter case, the surfactant distribution between oil and water and the behaviour of the resulting Winsor systems are central to surfactant science and to an understanding of the formation of emulsions and microemulsions. Surfactant layers on particle or droplet surfaces can confer stability on dispersions including emulsions, foams, and particulate dispersions. The stability is dependent on the surface forces between droplet or particle surfaces and the way in which they change with particle separation. Surface forces are also implicated in wetting processes and thin liquid film formation and stability. The rheology of adsorbed films on liquids and of bulk colloidal dispersions is covered in two chapters. Like surfactant molecules, small solid particles can adsorb at liquid/fluid interfaces and the final two chapters focus on particle adsorption, the behaviour of adsorbed particle films and the stabilization of Pickering emulsions.
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Schairer, John R., and Steven J. Keteyian. Pathophysiology and causes of pericardial tamponade. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0166.

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Pericardial disease leading to pericardial effusion (PEF) is a common clinical disorder. The most common causes are viral infections, metastatic cancer, renal disease, and bleeding disorders. PEF that accumulates slowly can become quite large before haemodynamic embarrassment occurs, while PEF that accumulates rapidly from trauma or aortic dissection can be small,yet cause haemodynamic embarrassment. As the PEF increases in size, the pressure in the pericardial space increases, leading to a decrease in atrial and ventricular chamber sizes, and limiting filling of the chambers. Ultimately, cardiac output is decreased,resulting in cardiac tamponade. When the limits of the pericardial stretch are reached, the volume in the pericardial sac becomes fixed. Any additional increase of PEF results in decreased cardiac size and any change in chamber size with respiration results in a paradoxical change in size of the other chambers. Tamponade is divided into three phases based on changes in pericardial and arterial pressure and cardiac output. Doppler echocardiography is the cornerstone of the diagnosis, follow-up, and management of PEF. It provides information about the presence, size, and location of the PEF, its impact on right ventricle, right atrium, and inferior vena cava size, and assesses tamponade physiology. Comorbid conditions may modify the signs of tamponade and need to be considered during the clinical assessment. Tamponade is not an all-or-nothing diagnosis, but instead should be viewed along a continuum of progressively worsening haemodynamics.
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