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Books on the topic 'HIV Receptors'

Author: Grafiati
Published: 4 June 2021
Last updated: 1 February 2022

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1

Dimitrov, Dimiter S. HIV and membrane receptors. New York: Chapman & Hall, 1997.

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2

Meucci, Olimpia. Chemokine receptors and neuroAIDS: Beyond co-receptor function and links to other neuropathologies. New York: Springer, 2010.

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3

O, Freed Eric, and SpringerLink (Online service), eds. HIV Interactions with Host Cell Proteins. Berlin, Heidelberg: Springer-Verlag Berlin Heidelberg, 2010.

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4

Clavel, François. HIV: Portrait of a complex retrovirus, [and], A second receptor for AIDS virus? Sudbury, Ont: Laurentian University, School of Translators and Interpreters, 1996.

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5

Dimitrov, Dimiter S. HIV Receptors And Membrane Receptors. Landes Bioscience, 2005.

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6

Dimitrov, Dimiter S. HIV And Membrance Receptors. 2nd ed. Landes Bioscience, 2006.

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7

(Editor), D. S. Dimitrov, and C. C. Broder (Editor), eds. Hiv and Membrane Receptors (Medical Intelligence Unit). Springer Verlag, 1997.

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8

1950-, O'Brien Thomas, ed. Chemokine receptors and AIDS. New York: Marcel Dekker, 2002.

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9

B, Kendow Lawrence, ed. AIDS vaccines, HIV receptors, and AIDS research. New York: Nova Science Publishers, 2008.

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10

Meucci, Olimpia. Chemokine Receptors and NeuroAIDS. Springer, 2010.

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11

Dimitrov, Dimiter S., and Christopher C., Ph.D. Broder. HIV And Membrane Receptors (Medical Intelligence Unit). R G Landes Co, 1997.

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12

Meucci, Olimpia. Chemokine Receptors and NeuroAIDS: Beyond Co-Receptor Function and Links to Other Neuropathologies. Springer, 2014.

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13

Livingston, Schuyler, Benjamin Young, Martin Markowitz, Poonam Mathur, and Bruce L. Gilliam. HIV Virology. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190493097.003.0017.

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HIV is a member of the lentivirus subfamily of retroviruses. Two distinct groups of viruses are pathogenic in humans: HIV-1 and HIV-2. Both are transmitted sexually and known to cause immunodeficiency disease. HIV enters the cell through use of the CD4 receptor and chemokine co-receptors, primarily CCR5 and CXCR4. The viral genome is transcribed from RNA to DNA by reverse transcriptase and integrated into the host genome by integrase. The HIV genome encodes 15 proteins, comprising three categories: structural, regulatory, and accessory. After budding from the host cell, the virus matures into its infectious form through cleavage of viral precursor proteins by protease.
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14

Genealogy of a Gene: Patents, HIV/AIDS, and Race. MIT Press, 2015.

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15

Jackson, Myles W. Genealogy of a Gene: Patents, HIV/AIDS, and Race. MIT Press, 2015.

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16

Jackson, Myles W., and Jed Z. Buchwald. Genealogy of a Gene: Patents, HIV/AIDS, and Race. MIT Press, 2015.

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17

Jackson, Myles W., and Jed Z. Buchwald. Genealogy of a Gene: Patents, HIV/AIDS, and Race. MIT Press, 2015.

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18

Spearman, Paul, and Eric O. Freed. HIV Interactions with Host Cell Proteins. Springer, 2010.

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19

Rowell, Geoffrey. Anglican Theological Receptions. Edited by Frederick D. Aquino and Benjamin J. King. Oxford University Press, 2018. http://dx.doi.org/10.1093/oxfordhb/9780198718284.013.26.

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The Anglican reception of Newman was coloured for at least the fifty years following his death by the sense of loss, even betrayal, consequent upon his move to the Roman Catholic Church and his disillusionment with the Via Media ecclesiology of a ‘reformed Catholicism’ that he had advocated as an Anglican. Nevertheless there were those, such as the Anglo-Catholic Lord Halifax, who continued to find inspiration in Newman. Michael Ramsey and Pope Paul VI both responded positively to his writings, and the shift in ecumenical attitudes in Vatican II brought a renewed Anglican appreciation of him, particularly in the acceptance of the development of doctrine. Appreciation was especially shown in Anglican evaluations on the centenary of Newman’s death, though sometimes mixed with criticism.
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20

Chou, Harris H. W. Expressions of TGF-beta receptors in human placenta and regulation of HIF-1alpha expression in cell lines. 2004.

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21

Gray, Vivienne. Thucydides and His Continuators. Edited by Sara Forsdyke, Edith Foster, and Ryan Balot. Oxford University Press, 2017. http://dx.doi.org/10.1093/oxfordhb/9780199340385.013.41.

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This chapter discusses the ways in which later historians completed the unfinished history of Thucydides. Cratippus (the author of the Hellenica Oxyrhynchia), Xenophon and Theopompus all wrote completions of Thucydides. They also attached continuations to their completions, going well beyond the endpoint Thucydides envisaged at 5.26. This chapter mentions the continuations only where relevant, however, choosing instead to focus on the completions because they are our first receptions of Thucydides. It considers the ways in which they did or did not imitate their great predecessor and how in other ways they might have engaged with his narrative. Xenophon’s completion is the main focus because it is the only one that is fully extant.
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22

Biloshytsky, Vadym, and Roman Cregg. Pioneering use of gene therapy for pain. Edited by Paul Farquhar-Smith, Pierre Beaulieu, and Sian Jagger. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780198834359.003.0083.

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The landmark paper discussed in this chapter is ‘Gene therapy for pain: Results of a Phase I clinical trial’, published by Fink et al. in 2011. In this study, the first of its kind, researchers studied the efficacy and safety of a modified herpes simplex virus (HSV) vector used to deliver PENK, which encodes proenkephalin, which is cleaved into the enkephalin peptides Met-enkephalin and Leu-enkephalin, which induce analgesia by acting on opioid receptors. The development of the HSV vector was based in part on results studies in which adenovirus, adeno-associated virus, or non-viral vectors were used to overexpress genes. Overexpression of a variety of large molecules leads to a reduction in pain-related behaviour in animals. Gene therapy in the treatment of chronic pain seems to offer a promising alternative to systemic or highly invasive therapies. However, additional research is needed to determine the safety, effectiveness, and cost-efficiency of this approach.
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23

Baloh, Robert W. Breuer’s Experiments on the Semicircular Canals and Otolith Organs. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780190600129.003.0006.

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After his groundbreaking work in the mid-1860s, Josef Breuer continued to perform experiments on the inner ear balance receptors in animals. He studied the macules of fish, reptiles, and birds and noted that all these creatures had three macules arranged in the planes of the semicircular canals, perpendicular to one another. By contrast, mammals had only two macules located in the utricle (horizontal plane) and saccule (vertical plane), again perpendicular to each other. He developed the concept of “slip” to describe the movement of the otoconial membrane over the underlying sensory epithelium that occurred with linear displacement or gravity. He developed a mathematical model to hypothesize that in humans there was only one combination of responses from the two macules on each side for a single head position in space.
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24

Derrick, Stephanie L. Conclusion. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198819448.003.0007.

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The emphasis of this monograph has been on the historical, cultural, religious, and social factors that shaped C. S. Lewis and his reception. Until recently those who have considered the subject have attributed his popularity to virtues of the man himself. The fact that Lewis, in effect, was an image, a mitigated commercial product, a platform, has largely been overlooked. A critical component of Lewis’s reception is the opportunities that education provided the middle classes for social mobility in the twentieth century and the social divisions and anxieties attendant upon those evolutions. Of equal importance is the timing of Lewis’s life and publications with print history and the rise of mass media and entertainment. Lewis’s platform as a contrarian Christian resisting modernity and his reactions to the intellectual, social, and religious changes of his day made the critical difference to his transatlantic receptions.
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25

Aquino, Frederick D., and Benjamin J. King, eds. The Oxford Handbook of John Henry Newman. Oxford University Press, 2018. http://dx.doi.org/10.1093/oxfordhb/9780198718284.001.0001.

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This Handbook brings together leading scholars to cover the primary and secondary literature on John Henry Newman’s life and writings, and explore his ongoing relevance. Part I grounds Newman’s works in the places, cultures, and networks of relationships in which he lived. Part II looks particularly at the writers who shaped Newman’s thought. Part III engages critically and appreciatively with select theological, philosophical, and literary themes in his writings. Part IV continues the work begun in Receptions of Newman (Aquino and King 2015), examining how his writings have shaped conversations in the Anglican and Roman Catholic traditions of which he was part and in the university, historiography, and literature in which he worked. This Handbook will serve as an important resource for critical and appreciative exploration of the person, writings, controversies, and legacy of Newman.
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26

McManus, Laurie. Brahms in the Priesthood of Art. Oxford University Press, 2021. http://dx.doi.org/10.1093/oso/9780190083274.001.0001.

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Brahms in the Priesthood of Art: Gender and Art Religion in the Nineteenth-Century German Musical Imagination explores the intersection of gender, art religion (Kunstreligion), and other aesthetic currents in Brahms reception of the nineteenth and early twentieth centuries. In particular, it focuses on the theme of the self-sacrificing musician devoted to his art, or “priest of music,” with its quasi-mystical and German Romantic implications of purity seemingly at odds with the lived reality of Brahms’s bourgeois existence. While such German Romantic notions of art religion informed the thinking on musical purity and performance, after the failed socio-political revolutions of 1848/49, and in the face of scientific developments, the very concept of musical priesthood was questioned as outmoded. Furthermore, its essential gender ambiguity, accommodating such performing mothers as Clara Schumann and Amalie Joachim, could explain why Brahms never married while leaving the composer open to speculation about his health and masculinity. Supportive critics combined elements of masculine and feminine values with a muddled rhetoric of prophets, messiahs, martyrs, and other art-religious stereotypes to account for the special status of Brahms and his circle. Detractors tended to locate these stereotypes in more modern, fin-de-siècle psychological frameworks that scrutinized the composer’s physical and mental well-being. In analyzing these receptions side by side, this book revises the accepted image of Brahms, recovering lost ambiguities in his reception. It resituates him not only in a romanticized priesthood of art but also within the cultural and gendered discourses overlooked by the absolute music paradigm.
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27

Cox, Fiona. Conclusion. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198779889.003.0013.

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The conclusion summarizes the significant and shaping contribution made to Ovidian reception by these third-wave women writers, and evaluates the implications for future receptions. An analysis of the extraordinary journey that Ovid has taken with contemporary women writers—that has seen him enter the virtual world of the internet, a world where gender transformation has become possible, a world that is itself in a process of constant transformation through the trafficking of refugees and the experience of contemporary exiles —has demonstrated how the ‘strange monsters’ housed within these contemporary ‘writing women’ affirm Ovid’s worlds of wonder and enchantment. In their hands Ovid’s song stretches into the future, as he continues to give voice to today’s women.
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28

Derrick, Stephanie L. The Fame of C. S. Lewis. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198819448.001.0001.

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This book considers the history of British literary scholar, author and Christian apologist C. S. Lewis’s fame from the 1940s through the present and compares his contrasting patterns of reception in Britain and America. Lewis was both an esteemed literary figure and a divisive personality among his colleagues at Oxford and Cambridge Universities, who recognized his penchant for projecting a persona. It took the outbreak of the Second World War and invitations from Christian leaders to draw Lewis into crafting popular Christian apologetics. Yet Lewis’s reasons for writing books that were accessible to a broad audience, including his children’s books, were rooted in a literary theory informed by his early reading life in Edwardian Belfast and his objections to literary modernism. The reception of Lewis’s popular works in America was shaped by the fact that American readers did not appreciate Lewis’s literary and cultural context. His posthumous fame, furthermore, should be accredited in part to factors independent of the qualities of his work: e.g. the publishing history of his books, the rise of visual media, the history of evangelicalism, and the manipulation of his legacy by the C. S. Lewis Estate. The evolution of rival portraits of Lewis as a Christian apologist and a children’s author is equally part of this story. Lewis’s platform as a contrarian Christian resisting modernity and his reactions to the intellectual, social, and religious changes of his day made the critical difference to his disparate transatlantic receptions.
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29

Miller, Mitchell. The Reception of Hesiod by the Early Pre-Socratics. Edited by Alexander C. Loney and Stephen Scully. Oxford University Press, 2018. http://dx.doi.org/10.1093/oxfordhb/9780190209032.013.42.

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The early pre-Socratics’ major speculative and critical initiatives—in particular Anaximander’s conceptions of the justice of the cosmos and of the apeiron as its archē and Xenophanes’s polemics against immorality and anthropomorphism in the depiction of the gods and against any claim to divine inspiration—appear to break with Hesiod’s form of thought. But the conceptual, critical, and ethical depth of Hesiod’s own rethinking of the lore that he inherited complicates this picture. Close examination of each of their major initiatives together with the relevant passages in Hesiod shows that even in the course of departing from his thought, Anaximander and Xenophanes also reappropriate and renew it. A postscript to this chapter poses some questions for future inquiry into Heraclitus’s and Parmenides’s receptions of Hesiod.
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30

Ingleheart, Jennifer. Here Aphrodite Is Not. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198819677.003.0006.

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Bainbrigge’s closet drama is explored from a number of perspectives. These include its debt to Victorian classical burlesques, and responses to other versions of the myth of Achilles, including Homer’s. This chapter explores Bainbrigge’s dramatization of the secrecy that surrounds homoerotic writing, and its use of homoerotic codes. It interrogates the radical homoerotic literary heritage Bainbrigge lays claim to, and his portrayal of lesbianism as equivalent to male homosexuality, not least via a tradition of homoerotic receptions of Sappho, including those of Swinburne and John Addington Symonds. The chapter further explores Bainbrigge’s comments on the links between love between males and classical education, and the continuities between ancient and modern sexualities. The play offers an anarchic range of queer options, encompassing gender fluidity, cross-dressing, and a very wide variety of sexual possibilities and roles.
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31

Bannwarth, Bernard, and Francis Berenbaum. Systemic analgesics (including paracetamol and opioids). Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199668847.003.0029.

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Apart from non-steroidal anti-inflammatory drugs (NSAIDs), there are only two categories of systemic analgesics, namely paracetamol (acetaminophen) and opioids, that are currently available worldwide for clinical use. Paracetamol is poorly effective in relieving pain and improving function in patients with symptomatic osteoarthritis (OA). Furthermore, its safety profile is less favourable than classically thought. In fact, there is evidence paracetamol acts as a weak inhibitor of the cyclooxygenase enzymes. Given that paracetamol poses a lower risk of severe adverse events than NSAIDs while being better tolerated than opioids, it is usually considered as the first-line systemic analgesic for OA. Commonly prescribed opioids are primarily agonists of the mu receptors, thereby producing similar desirable (analgesia) and untoward effects. Meta-analyses of short-term clinical trials showed that, on average, the modest clinical benefits of opioids did not outweigh the side effects in patients with knee or hip OA. Accordingly, most current guidelines support the use of opioids for selected OA patients only (e.g. patients who have not had an adequate response to other treatment modalities and are not candidates for total joint arthroplasty). In view of the limited efficacy and/or potential harms of available analgesics, particular attention was paid to novel painkillers, especially nerve growth factor (NGF) antagonists. Although these agents provided clinically meaningful improvements in pain and physical function in patients with hip or knee OA, they lead to severe side effects, including rapidly destructive arthropathies and neuropathies. Thus, if approved for marketing, NGF antagonists would be reserved for selected and well-defined patients with OA.
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32

Mease, Philip. Neurobiology of pain in osteoarthritis. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199668847.003.0013.

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Significant advances in our understanding of the neurobiology of pain in osteoarthritis (OA) have occurred in the last decade and are herein summarized. Pain is the predominant symptom of OA and occurs at multiple levels from non-cartilage peripheral tissues to spinal cord, and brain and back. At each level, nerve function is regulated by complex ionic channels, neuropeptide expression, and cytokine and chemokine activity. Previously considered a non-inflammatory condition, it is now recognized that cell proliferation and inflammatory cytokine production occurs in OA synovium, contributing to peripheral sensitization. Genetic profile influences nociceptive neuropeptide expression and thus, pain perception. Both peripheral and central sensitizing factors, including increased neuropeptide and microglial activity, lead to pain augmentation and persistence. Pain processing in brain centres such as the somatosensory cortex and insula are influenced by affective areas such as the amygdala. Descending receptor pathways through the midbrain to the dorsal horn, such as norepinephrine, serotonin, opioid, and cannabinoid, normally provide pain inhibitory function but this function may be diminished in chronic pain states such as OA, leading to allodynia and hyperalgesia. Functional neuroimaging has contributed to our understanding of the complex interplay of peripheral and central mechanisms. Recent evidence that grey matter volume decrease in chronic pain states may be reversible (e.g. after pain relief post OA hip arthroplasty) illuminates the potential for central neuroplasticity. Greater understanding of the neurobiology of OA pain provides evidence for therapeutic approaches that address peripheral and/or central pain mechanisms and provides a guide for future targeted pain therapeutics.
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33

Knust, Jennifer, and Tommy Wasserman. To Cast the First Stone. Princeton University Press, 2018. http://dx.doi.org/10.23943/princeton/9780691169880.001.0001.

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The story of the woman taken in adultery features a dramatic confrontation between Jesus and the Pharisees over whether the adulteress should be stoned as the law commands. In response, Jesus famously states, “Let him who is without sin be the first to throw a stone at her.” This book traces the history of this provocative story from its first appearance to its enduring presence today. Likely added to the Gospel of John in the third century, the passage is often held up by modern critics as an example of textual corruption by early Christian scribes and editors, yet a judgment of corruption obscures the warm embrace the story actually received. The book traces the story's incorporation into Gospel books, liturgical practices, storytelling, and art, overturning the mistaken perception that it was either peripheral or suppressed, even in the Greek East. It explores the story's many different meanings. Taken as an illustration of the expansiveness of Christ's mercy, the purported superiority of Christians over Jews, the necessity of penance, and more, this vivid episode has invited any number of creative receptions. This history reveals as much about the changing priorities of audiences, scribes, editors, and scholars as it does about an “original” text of John. The book calls attention to significant shifts in Christian book cultures and the enduring impact of oral tradition on the preservation—and destabilization—of scripture.
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