Relevant bibliographies by topics / Hib

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Hib'

Author: Grafiati
Published: 4 June 2021
Last updated: 30 January 2023

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Journal articles on the topic "Hib"

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Yunizar, Yunizar, Asriwati Asriwati, and Anto J. Hadi. "Perilaku Ibu dalam Pemberian Imunisasi DPT/Hb-Hib di Desa Sinabang Kecamatan Simeulue Timur." Jurnal Kesehatan Global 1, no. 2 (December 11, 2018): 61. http://dx.doi.org/10.33085/jkg.v1i2.3956.

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Capaian imunisasi DPT/HB-HiB 2017 di Desa Sinabang Kecamatan Simeulue Timur 71,3 % mendapat Imunisasi DPT/HB-HIB1, 68,2% mendapat Imunisasi DPT/HB-HIB2 dan 63,3% mendapat Imunisasi DPT/HB-HIB3. Terkait dengan pengetahuan, sikap, keterampilan, dukungan petugas kesehatan dan dukungan suami/keluarga. Tujuan Penelitian ini bertujuan untuk mengetahui perilaku ibu dalam pemberian imunisasi DPT/HB-HiB di Desa Sinabang Kecamatan Simelue Timur tahun 2018. Metode Penelitian yang digunakan adalah kombinasi metode kuantitatif dan kualitatif (mixed method) dengan pendekatan triangulasi konkuren. Lokasi penelitian di desa Sinabang Kecamatan Simeulue Timur. Populasi penelitian ini 44 ibu dengan total sampel dan informan dalam penelitian ini 4 orang ibu yang memiliki bayi berumur < 1 tahun, 1 orang bidan di Puskesmas Simeulue Timur dan 1 orang Kepala Puskesmas. Hasil penelitian menunjukkan pengetahuan ibu (p<α=0,05), sikap (p<α=0,05), keterampilan (p>α=0,05), dukungan petugas kesehatan (p>α=0,05) dan dukungan suami/keluarga (p>α=0,05) dan variabel yang paling memengaruhi adalah variabel pengetahuan. Kesimpulan penelitian adalah pengetahuan, sikap dan dukungan suami/keluarga berpengaruh terhadap prilaku ibu dalam pemberian imunisasi DPT/HB-HiB dan keterampilan dan dukungan petugas kesehatan tidak berpengaruh.
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Konini, Angjelina, Mingsong Kang, and Seyed M. Moghadas. "Simulating Immune Interference on the Effect of a Bivalent Glycoconjugate Vaccine againstHaemophilus influenzaeSerotypes “a” and “b”." Canadian Journal of Infectious Diseases and Medical Microbiology 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/5486869.

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Objective.We sought to evaluate the immune responses to a bivalentHaemophilus influenzaeglycoconjugate vaccine against serotypes “a” (Hia) and “b” (Hib) in the presence of the preexisting immunity to Hib.Methods.We developed a stochastic simulation model of humoral immune response to investigate the antigenic challenge of a bivalent combined glycoconjugate vaccine and a bivalent unimolecular glycoconjugate vaccine. We compared simulation outcomes in the absence of any preexisting immunity with an already primed immune response having specific memory B cells and/or anti-Hib antibodies.Results.The simulation results show that the preexisting immune responses to Hib or carrier protein (CP) may significantly impede the production of anti-Hia antibodies by a unimolecular vaccine. In contrast, the production of anti-Hia antibodies using a combined vaccine is inhibited only in the presence of CP immune responses.Conclusions.Preexisting immunity to Hib and CP may play a critical role in the development of immune responses against Hia or Hib using bivalent combined and unimolecular vaccine formulations. Our results suggest that a bivalent combined glycoconjugate vaccine with a carrier protein not previously used in Hib conjugate vaccines may be an effective formulation for generating immune responses to protect against both Hib and Hia infections.
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Ulanova, Marina. "Global Epidemiology of Invasive Haemophilus influenzae Type a Disease: Do We Need a New Vaccine?" Journal of Vaccines 2013 (February 27, 2013): 1–14. http://dx.doi.org/10.1155/2013/941461.

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Until recently, the significance of invasive disease caused by Haemophilus influenzae serotype a (Hia), in contrast to H. influenzae serotype b (Hib), has been largely underestimated. However, during the last decade, Hia was recognized as an important pathogen causing severe infections in young children with a high case-fatality rate comparable to Hib disease before the introduction of pediatric immunization against this infection. Remarkably, the highest incidence rates of invasive Hia disease have been found in some indigenous populations, such as North American Indians and Inuit of Alaska and Northern Canada, reaching the order of magnitude of the incidence rates of Hib in the pre-Hib vaccine era. The reasons for an increased susceptibility to Hia infection among some specific populations groups are unknown. The goal of this paper is to summarize the current knowledge on Hia global epidemiology and to discuss potential prevention of this infection using specific immunization.
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Slack, Mary Paulina Elizabeth. "Long Term Impact of Conjugate Vaccines on Haemophilus influenzae Meningitis: Narrative Review." Microorganisms 9, no. 5 (April 21, 2021): 886. http://dx.doi.org/10.3390/microorganisms9050886.

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H. influenzae serotype b (Hib) used to be the commonest cause of bacterial meningitis in young children. The widespread use of Hib conjugate vaccine has profoundly altered the epidemiology of H. influenzae meningitis. This short review reports on the spectrum of H. influenzae meningitis thirty years after Hib conjugate vaccine was first introduced into a National Immunization Program (NIP). Hib meningitis is now uncommon, but meningitis caused by other capsulated serotypes of H. influenzae and non-typeable strains (NTHi) should be considered. H. influenzae serotype a (Hia) has emerged as a significant cause of meningitis in Indigenous children in North America, which may necessitate a Hia conjugate vaccine. Cases of Hie, Hif, and NTHi meningitis are predominantly seen in young children and less common in older age groups. This short review reports on the spectrum of H. influenzae meningitis thirty years after Hib conjugate vaccine was first introduced into a NIP.
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TSANG, R. S. W., M. G. BRUCE, M. LEM, L. BARRETO, and M. ULANOVA. "A review of invasiveHaemophilus influenzaedisease in the Indigenous populations of North America." Epidemiology and Infection 142, no. 7 (March 5, 2014): 1344–54. http://dx.doi.org/10.1017/s0950268814000405.

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SUMMARYHistorically, the highest incidence rates of invasiveHaemophilus influenzaedisease in the world were found in North American and Australian Indigenous children. Although immunization againstH. influenzaetype b (Hib) led to a marked decrease in invasive Hib disease in countries where it was implemented, this disease has not been eliminated and its rates in Indigenous communities remain higher than in the general North American population. In this literature review, we examined the epidemiology of invasiveH. influenzaedisease in the pre-Hib vaccine era, effect of carriage on disease epidemiology, immune response toH. influenzaeinfection and Hib vaccination in Indigenous and Caucasian children, and the changing epidemiology after Hib conjugate vaccine has been in use for more than two decades in North America. We also explored reasons behind the continued high rates of invasiveH. influenzaedisease in Indigenous populations in North America.H. influenzaetype a (Hia) has emerged as a significant cause of severe disease in North American Indigenous communities. More research is needed to define the genotypic diversity of Hia and the disease burden that it causes in order to determine if a Hia vaccine is required to protect the vulnerable populations.
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Sadeghi-Aval, Pouya, Raymond SW Tsang, Frances B. Jamieson, and Marina Ulanova. "Emergence of Non-Serotype b EncapsulatedHaemophilus influenzaeas a Cause of Pediatric Meningitis in Northwestern Ontario." Canadian Journal of Infectious Diseases and Medical Microbiology 24, no. 1 (2013): 13–16. http://dx.doi.org/10.1155/2013/828730.

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Before the introduction of the conjugate vaccine,Haemophilus influenzaeserotype b (Hib) was the leading cause of bacterial meningitis in children. Although successful in reducing Hib cases, the vaccine confers no protection against other serotypes ofH influenzae, such as a (Hia), or f (Hif). The emergence of invasive disease caused by non-Hib in northwestern Ontario (38 cases between 2002 and 2008) with predominance of Hia was previously reported by the authors. At that time, no cases of pediatric meningitis caused byH influenzaewere recorded in the region. Continued surveillance identified 12 new cases of invasive non-Hib between January 2009 and July 2011. Among these cases, three young children developed meningitis with severe complications caused by Hia or Hif. The present article describes these cases along with the characteristics of recentH influenzaeisolates from the region, (ie, their genetic background and antibiotic sensitivity). The findings point to the clonal nature of circulating Hia strains as well as to an increase in frequency and severity of pediatric invasiveH influenzaeinfections in northwestern Ontario.
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Yang, Yan-ping, Wayne R. Thomas, Pele Chong, Sheena M. Loosmore, and Michel H. Klein. "A 20-Kilodalton N-Terminal Fragment of the D15 Protein Contains a Protective Epitope(s) against Haemophilus influenzae Type a and Type b." Infection and Immunity 66, no. 7 (July 1, 1998): 3349–54. http://dx.doi.org/10.1128/iai.66.7.3349-3354.1998.

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ABSTRACT A conserved 80-kDa minor outer membrane protein, D15, ofHaemophilus influenzae has been shown to be a protective antigen in laboratory animals against H. influenzae type a (Hia) or type b (Hib) infection. To localize the protective B-cell epitope(s) within the D15 protein and to further explore the possibility of using synthetic peptides as vaccine antigens, a 20-kDa N-terminal fragment of D15 protein (truncated D15 [tD15]) was expressed as a fusion protein with glutathioneS-transferase in Escherichia coli. The tD15 moiety was cleaved from glutathione S-transferase by using thrombin and purified to homogeneity. The purified soluble tD15 appeared to contain immunodominant protective epitope(s) against Hia and Hib, since rabbit antisera directed against tD15 were capable of protecting infant rats from Hia or Hib bacteremia. The ease of purification of soluble tD15, therefore, makes it a better candidate antigen than the full-length recombinant D15 which is produced as inclusion bodies in E. coli. Furthermore, both the purified tD15 fragment and a mixture of tD15-derived peptides spanning amino acid residues 93 to 209 of the mature D15 protein were capable of inhibiting the protection against Hib conferred on infant rats by rabbit anti-tD15 antiserum, indicating that the protective epitopes of D15 may not be conformational. However, the administration of pooled rabbit immune sera raised against the same panel of peptides failed to protect infant rats from Hib infection.
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WAN SAI CHEONG, J., H. SMITH, C. HENEY, J. ROBSON, S. SCHLEBUSCH, J. FU, and C. NOURSE. "Trends in the epidemiology of invasiveHaemophilus influenzaedisease in Queensland, Australia from 2000 to 2013: what is the impact of an increase in invasive non-typableH. influenzae(NTHi)?" Epidemiology and Infection 143, no. 14 (March 12, 2015): 2993–3000. http://dx.doi.org/10.1017/s0950268815000345.

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SUMMARYFollowing the introduction of vaccination againstHaemophilus influenzaetype b (Hib), cases of invasive encapsulated Hib disease have decreased markedly. This study aimed to examine subsequent epidemiological trends in invasiveH. influenzaedisease in Queensland, Australia and in particular, assess the clinical impact and public health implications of invasive non-typableH. influenzae(NTHi) strains. A multicentre retrospective study was conducted from July 2000 to June 2013. Databases of major laboratories in Queensland including Queensland Forensic and Scientific Services (jurisdictional referral laboratory for isolate typing) were examined to identify cases. Demographic, infection site, Indigenous status, serotype, and mortality data were collected. In total, 737 invasive isolates were identified, of which 586 (79·5%) were serotyped. Hib, NTHi and encapsulated non-b strains, respectively, constituted 12·1%, 69·1% and 18·8% of isolates. The predominant encapsulated non-b strains were f (45·5%) and a (27·3%) serotypes. Of isolates causing meningitis, 48·9% were NTHi, 14·9% Hib, 14·9% Hie, 10·6% Hif, 6·4% Hia and 4·3% were untyped. During the study period, there was an increase in the incidence of invasive NTHi disease (P= 0·007) with seasonal peaks in winter and spring (P< 0·001). The incidence of Hib disease (P= 0·295) and of encapsulated non-b disease (P= 0·122) did not change significantly. Highest overall incidence was in infants, Indigenous, and elderly patients. Australian Indigenous patients were more likely to have Hia (P> 0·001) and Hib (P= 0·039) than non-Indigenous patients. In Queensland, invasiveH. influenzaedisease is now predominantly encountered in adults and most commonly caused by NTHi strains with demonstrated pathogenicity extending to otherwise young or immunocompetent individuals. Routine public health notification of these strains is recommended and recent available immunization options should be considered.
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Xirogianni, Athanasia, Theano Georgakopoulou, Vassileios Patsourakos, Ioanna Magaziotou, Anastasia Papandreou, Stelmos Simantirakis, and Georgina Tzanakaki. "Impact of a Single-Tube PCR Assay for the Detection of Haemophilus influenzae Serotypes a, c, d, e and f on the Epidemiological Surveillance in Greece." Microorganisms 10, no. 7 (July 7, 2022): 1367. http://dx.doi.org/10.3390/microorganisms10071367.

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Background: The decrease in the rate of meningitis due to Haemophilus influenzae type b after vaccine introduction and a possible change in epidemiology of H. influenzae disease highlights the need for continuous serotype surveillance. Methods: A single-tube multiplex PCR assay for serotyping of H. influenzae was developed and deployed. Results: During 2003–2020, 108 meningitis cases due to H. influenzae were notified; 86 (80%) were confirmed and serotyped by molecular methods. The overall specificity and sensitivity of the assay were estimated (100% PPV and NPV respectively). The overall mean annual reported incidence for H. influenzae was 0.02, while for Hib and non-b meningitis equaled 0.02 and 0.03 per 100 000, respectively. Analysis by age group revealed that H. influenzae peaks in toddlers and children 0–4 years and in adults >45 years old. Among the serotyped cases, 39.8% were identified as Hib, 46.3% as NTHi, and 0.9% and 2.8% as serotypes a (Hia) and f (Hif)) respectively. Conclusions: Low incidence due to Hib was observed while non-typeable H. influenzae (NTHi) and serotypes Hia and Hif seem to emerge. The application of the current assay discloses the ongoing change of invasive H. influenzae disease trends during the Hib post-vaccine era.
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Cerqueira, Ashley, Sarah Byce, Raymond S. W. Tsang, Frances B. Jamieson, Julianne V. Kus, and Marina Ulanova. "Continuing surveillance of invasive Haemophilus influenzae disease in northwestern Ontario emphasizes the importance of serotype a and non-typeable strains as causes of serious disease: a Canadian Immunization Research Network (CIRN) Study." Canadian Journal of Microbiology 65, no. 11 (November 2019): 805–13. http://dx.doi.org/10.1139/cjm-2019-0210.

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In the post-Haemophilus influenzae serotype b (Hib) vaccine era, invasive H. influenzae serotype a (Hia) disease emerged in Canadian First Nation, Inuit, and Alaskan Indigenous populations. Previous studies by our group found a high incidence of invasive Hia disease in northwestern Ontario. We retrospectively reviewed 24 cases (4 pediatric and 20 adult) of invasive H. influenzae disease hospitalized at the northwestern Ontario regional hospital between August 2011 and June 2018. The objectives were to further document the changing epidemiology of invasive H. influenzae disease in the region and to discuss potential control measures. Twenty-two H. influenzae isolates were serotyped and characterized using molecular-biological methods. Of the serotyped cases, there were 2 Hib, 9 Hia, and 11 non-typeable (NTHi). All Hia isolates belonged to the most common sequence types (ST) found in Canada (ST-23 and ST-929); 8 out of 9 were pan susceptible to antibiotics. One (11%) of 9 Hia and 5 (45%) of 11 NTHi cases were fatal. Our data on the consistent presence of serious invasive H. influenzae disease, with 41% prevalence of Hia (9 out of 22 serotyped isolates) and 50% prevalence of NTHi strains (11 out of 22), emphasize the importance of continued surveillance of H. influenzae in the post-Hib vaccine era and are critical information to inform potential vaccine development.
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Dissertations / Theses on the topic "Hib"

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Coen, Pietro G. "Mathematical models of Haemophilus influenzae type b and Neisseria meningitidis." Thesis, University of Oxford, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.298260.

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Barbour, Marina Louise. "Conjugate vaccine and carriage of Haemophilus influenzae type b." Thesis, University of Oxford, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.358581.

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Dinan, Leonie Rita. "Antibody responses after Hib immunisation in premature and term infants /." Title page, table of contents and abstract only, 1998. http://web4.library.adelaide.edu.au/theses/09MPM/09mpmd583.pdf.

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Ladhani, Shamez N. "Investigations into the long-term impact of Haemophilus influenzae serptype b (Hib) immunisation on invasive H. influenzae disease, with particular emphasis on children with Hib vaccine failure." Thesis, Queen Mary, University of London, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.542039.

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Chen, Hsiang Yin. "The regulation of brown adipose tissue gene expression in HIB-1B cells." Thesis, University of Nottingham, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.575158.

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The main objective of this thesis is to contribute to our understanding of the regulation of brown adipose gene expression by examining the transcriptional regulation of the two key brown adipogenic genes, UCPl and PGCla during the initial stage of differentiation in a model brown adipocyte cell line. The principal findings were that UCP land PGC 1 a expression was induced by both forskolin and rosiglitazone, and that combination of these drugs produced a synergistic increase which required the full length promoters. These effects on UCPl and PGCla expression were partially suppressed by PKA and PPARy antagonists and results suggested that there is a cross-talk between PKA and PPARy signalling pathways. C~anges in brown adipogenic gene expression similarly provided evidence of cross-talk between PKA and PPARy signalling pathways which may explain the mechanism responsible for the synergistic effects offorskolin and rosiglitazone on UCPl expression. PPARy and CIEBPP, but not PGC 1 a overexpression, increased basal and stimulated UCP 1 mRNA. Similar results were observed with the 3.lkb UCPl-Luc reporter and co-overexpression ofPPARy with PGC 1 a markedly upregulated UCP 1 transcription in response to either forskolin or rosiglitazone. PGCla mRNA was increased in response to C/EBPP, but not PPARy overexpression and these results were confirmed using the 2.6kb PGCla-Luc reporter. PGC 1 a transcription was further up-regulated by co-overexpression of C/EBPP with PPARy in response to either forskolin or rosiglitazone. RIPl40 overexpression inhibited the effect of PG Cl a on rosiglitazone stimulated 3.lkb UCPl-Luc promoter activity. The results suggests that there are differences in transcriptional regulation between UCP 1 and PGCla promoters which indicate that the synergistic effect of cAMP and PPARy ligand stimulation on UCPl expression is a direct results of control of the PPRE and CRE on the UCPl promoter rather than indirect control though the PGCla promoter. vi
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Hadida, M. "Epidemiology of acute respiratory infections, transplacental transfer of antibodies and immunogenicity of a hib conjugate vaccine in Libyan infants." Thesis, University of Liverpool, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243199.

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Bago, Barbara Christina Barbosa. "Validação do processo de limpeza de tanque multiuso utilizado para formulação de vacinas." Universidade do Estado do Rio de Janeiro, 2010. http://www.bdtd.uerj.br/tde_busca/arquivo.php?codArquivo=2716.

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A validação de limpeza de equipamentos é requisito regulatório para assegurar que os procedimentos de limpeza removem os resíduos de produto e agente de limpeza existentes até um nível de aceitação pré-determinado, garantindo que não haja contaminação cruzada. A metodologia analítica escolhida para monitorar a ocorrência de contaminação cruzada foi a determinação de carbono orgânico total (TOC) por ser uma técnica não específica permitindo assim quantificar os resíduos antes e após o procedimento de limpeza. Para execução desta validação foi selecionado o pior caso em relação ao contaminante. A vacina Hib foi escolhida como pior caso, pois possui maior aderência ao aço inox 316L, apresentando uma menor percentagem de recuperação, quando comparada à vacina Meningite A e C, sendo respectivamente de 93,0% e 98,4% para o tempo de extração de 30 segundos e 67,8% e 72,6% para o tempo de extração de 10 segundos. O resíduo aceitável de produto em água de rinsagem foi de 0,0007 g/mL de polissacarídeo (0,49 g/mL de TOC) e em swab foi de 0,006 g/mL de polissacarídeo (3,49 g/mL de TOC). As amostras retiradas para determinação de resíduo de produto foram analisadas e corrigidas pelo fator de recuperação deste resíduo para amostras de água de rinsagem que é de 98,5% e para amostras em swab que é de 98,4%. Já o resíduo aceitável para agente de limpeza (NaOH) foi de 3,5 g/mL que fornece um pH de 9,94, porém não existem evidências que a concentração calculada de resíduo de NaOH não interferirá quimicamente ao entrar em contato com a vacina. Assim o critério adotado foi o mesmo da água para injetáveis, segundo USP que é pH entre 5 e 7. As amostras retiradas para determinação de resíduo de agente de limpeza não foram corrigidas pelo fator de recuperação uma vez que o critério utilizado é muito mais crítico que o calculado. Todas as análises realizadas apresentaram resultados dentro dos parâmetros aceitáveis permitindo a conclusão de que o procedimento de limpeza para tanque de aço inox 316L é eficiente removendo os resíduos até níveis aceitáveis, evitando assim uma contaminação cruzada
The cleaning validation of equipments is a regulatory requirement to ensure that the procedure to remove residues of the product and the cleaning agent to a level of acceptance, ensuring no cross contamination. The analytical methodology chose to monitor the occurrence of cross-contamination was the determination of total organic carbon (TOC) as it is a non-specific technique allowing to quantify the residues before and after the cleaning procedure. For the execution of the validation it was selected the worst case regarding contaminant. The Hib vaccine was chosen as the worst case because it has greater adherence to stainless steel 316L, with a lower percentage of recovery when compared to vaccine meningitis A and C, being respectively 93.0% and 98.4% for the extraction time of 30 seconds and 67.8% and 72.6% for the extraction time of 10 seconds. The considered acceptable product residue in the rinsing water was 0.0007 mg/mL of polysaccharide (0.48 mg/mL of TOC) and in swab it was 0.006 mg/mL of polysaccharide (3.49 mg/mL of TOC). Samples took for determination of residual product has been analyzed and corrected by the recovery factor for this waste water samples by rinsing which is 98.5% and for samples in swab that is 98.4%. The acceptable residue for the cleaning agent (NaOH) was 3.512 mg/mL which provides a pH of 9.94, but there is no evidence that the concentration of residual NaOH does not chemically interfere in contact with the vaccine. Thus, the criterion used was the same as for water for injection, according to USP, that is between pH 5 and 7. Samples took for the determination of residual cleaning agent were not corrected by the recovery factor because the criterion used is much more critical than that calculated. All the analysis results were within the acceptable parameters allowing to conclude that the cleaning procedure for 316L stainless steel tank was effective, removing the waste to acceptable levels, thus, preventing from cross-contamination
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Martins, Fernanda Otaviano. "Avaliação da resposta imunológica humoral, em animais de experimentação, induzida pela combinação da vacina DTP-Hib com as vacinas meningocócicas B e C conjugada, desenvolvidas em Bio-Manguinhos." Instituto de Tecnologia em Imunobiológicos, 2011. https://www.arca.fiocruz.br/handle/icict/5918.

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Fundação Oswaldo Cruz. Instituto de Tecnologia em Imunobiológicos. Rio de Janeiro, RJ, Brasil.
A combinação de vacinas é uma estratégia de grande relevância para o Programa Nacional de Imunizações. Através dela, é possível aumentar a proteção a múltiplas doenças em uma única vacina, bem como diminuir as constantes visitas ao posto de saúde. Contudo, uma das desvantagens em relação a esse tipo de estratégia é a possibilidade de ocorrer interferência antigênica entre os seus componentes,o que pode resultar na diminuição da resposta imunológica. Devido a este fato, foi realizada uma combinação com vacinas já presentes no calendário brasileiro de imunizações (DTP-Hib) a vacinas experimentais em desenvolvimento em Bio-Manguinhos (meningocócica B e meningocócica C conjugada), com a finalidade de apresentar uma nova perspectivade produto a esta unidade bem como estabelecer a correlação antigênica entre esses componentes, comparando metodologias já padronizadas para este fim à metodologia alternativa (ELISA), além de avaliar a pirogenicidade e a interferência entre os componentes vacinais utilizados na combinação. A resposta imunológica aos componentes vacinais foiavaliada em camundongos suíços, NIH e cobaias Short-Hair pelo ELISA (VME, polissacarídeo C, PRRP, Bordetella pertussis) e os testes de soroneutralização in vivo(componentes tetânico e diftérico). Todos os componentes vacinais avaliados pelo ELISA induziram soroconversão nos animais 30 dias após a última imunização. Quando comparadas à vacina combinada completa, somente a resposta imunológica ao polissacarídeo C sofreu interferência de algum componente vacinal. Após novas combinações davacina meningocócica C conjugada às outras vacinas, pode-se concluir que avacinas DTP e Hib interagem positivamente na resposta daquela vacina. Em relação à soroneutralização in vivo, houve uma diminuição da potência dos componentes tetânicoe diftérico quando cobaias Short-Hair foram imunizadas com a vacina DTP-Hib combinada às vacinas meningocócicas B e C conjugada. Em contrapartida, na quantificação de IgG total em camundongos suíços imunizados com as duas combinações (DTP-Hib e DTP-Hib/B/C), não ocorreu diferença significativa entre os dois grupos. O teste de pirogenicidade realizado em coelhos comprovou que, quando combinadas entre si, às vacinas são capazes de aumentar a temperatura destes animais, provavelmente, devido àpresença de Bordetella pertussise VME de Neisseria meningitidisgrupo B. Apesar de não ter sido possível à comparação com ostestes padronizados, o ELISA mostrou-se muito satisfatório na pesquisa da resposta imunológica em camundongos. Embora preliminares, os resultados são muito importantes, pois introduzem novas perspectivas para a realização de outras combinações que atendam as demandas requisitadas pelo Programa Nacional de Imunizações.
The combination of vaccines is a great relevance strategy to the National Immunization Program. It enables increase protection to multiple diseases in a single injection, as well as reduces constant visits to health care. However, a disadvantage of this strategy is antigenic interference among vaccine components, resulting in immune response decreased. Due to this fact, a combination between vaccines of Brazilian immunization calendar (DTP-Hib) and experimental vaccines developed in Bio-Manguinhos (meningococcal B and meningococcal C conjugate) wasperformed, in order to present a new perspective of product to this unit and establish the antigenic correlation of these components, comparing standardized methodologies with alternative methodology (ELISA), besides evaluating pyrogenicity and interference ofcombined vaccine components. The immune response to vaccine components was evaluated in Swiss and NIH mice and Short-Hair guinea pigs by ELISA (OMV, polysaccharide C, PRP, Bordetella pertussis) and in vivoneutralization test (tetanus and diphtheria components). All vaccine components assessed by ELISA induced seroconversion rates 30 days after the last immunization in animals. The complete combined vaccine, interfered in the immune response to polysaccharide C. After new combinations of meningococcal C conjugate vaccine to other vaccines, we concluded that DTP and Hib vaccines induce a positive interaction in immune response to that vaccine. Regarding in vivoneutralization, there was a decrease of tetanus and diphtheria components potency when Short-Hair guinea pigs were immunized with DTP-Hib combined to B and C meningococcal conjugate vaccines. In contrast, when total IgG in Swiss mice immunizedwith the two combinations (DTP-Hib and DTP-Hib/B/C) was quantified, no significant difference was observed. Pirogenicity test in rabbits proved that complete combined vaccine increase the temperature of these animals, probably due to the presence of Bordetella pertussisand Neisseria meningitidisgroup B outer membrane vesicle. Although it was not possible comparision with standardized test, ELISA was a satisfactory test in studing immune response in mice. Although preliminary, the results are important because introduce new perspectives for other combinations could be done to atempt the required demands of National Immunization Program.
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Weissmueller, Nikolas T. "Needle-free vaccination : formulation and dermal delivery of diphtheria toxin CRM197 mutant." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:be74f39b-1f36-451c-8200-4f14b701bcee.

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The unsafe use of needles propagates cross infections with bloodborne pathogens and reduces the positive impact of vaccinations on global health. While a plethora of needle-free injection devices exist, the reformulation of protein-based vaccines is largely empirical and costly, which presents a barrier to their widespread clinical application. This thesis contributes to the identification of approaches that facilitate rapid vaccine reformulation and enhance the immunogenicity of needle-free dry-powder vaccines with the help of novel antigen delivery platforms. We hypothesised that the thermodynamic stabilisation of diphtheria toxin mutant 197 (CRM197), a glycoconjugate vaccine carrier protein, may enhance its structural preservation during spray-freeze-drying (SFD), and that its formulation in either soluble, surface-adsorbed, or nanoparticle form impacts the elicited immune response. Differential scanning fluorimetry was used to study the effect of excipients on the thermal stability of CRM197. Dry-powder formulation of CRM197 used i) encapsulation into a thermodynamically stabilising excipient matrix by SFD, ii) surface-immobilisation via physisorption onto a novel potassium-doped hydroxyapatite (kHA) carrier microparticle formed by molten salt synthesis, and iii) chemical conjugation and surface presentation on amphiphilic block copolymer nanoparticles that were incorporated into SFD-powders (SFD-NP). The structural integrity of CRM197 was assessed by size separation in addition to various spectral and thermal analysis methods. The immunogenicity of dry-powder CRM197 formulations was subsequently tested in vivo. The results suggest that the thermodynamic stability of CRM197 in solution does not ensure its structural stability during SFD. While needle-free dermal vaccination with kHA-adsorbed CRM197 induced comparable antibody titres to conventional IM injection of alum-adjuvanted CRM197, needle-free SFD and SFD-NP powders were less immunogenic. The highest mean IgG titre and most balanced Th1/Th2 response was achieved with nanoparticle-conjugated CRM197 by IM, which outperformed the current clinical standard. Therefore, future vaccine design should combine thermodynamic and kinetic stability screening, and place special emphasis on the delivery and structural presentation of the antigen to the immune system.
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Anwar, Kanar Shwan. "Adverse prevents in premature infants born before 28 + 0 weeks of gestation after vaccation with Synflorix (PhiD-CV) and Infanrix hexa (DTPaHBV-IPV/Hib)." Thesis, Örebro universitet, Institutionen för medicinska vetenskaper, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-52512.

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Books on the topic "Hib"

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Massachusetts. Department of Public Health. Hib vaccine. Boston, MA: Massachusetts Dept. of Public Health, 1992.

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Stephens, Nathalie. Species: Ex(hib)it. [Toronto]: BookThug, 2003.

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Stephens, Nathalie. Species ex(hib)it. Toronto, ON: BookThug, 2004.

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Azzopardi, Helen J. Invasive haemophilus influenzae disease in the post HIB vaccine era. Oxford: Oxford Brookes University, 1999.

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Olowokure, Babatunde. The impact of Hib conjugate vaccine on the epidemiology of invasive Haemophilus influenzae disease in the West Midlands and the effect of deprivation and other environmental risk factors: An ecological study, 1990-1994. [s.l.]: typescript, 1999.

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Belokosa, Bozana. Hip, hip, hip, hooray. Detroit, Mich: Harlo, 1986.

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Greg, Neri, ed. Hip, hip, hip, les dents! Markham, Ont: Scholastic, 2002.

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Waddell, Martin. Hip hip hip ! Coin coin ! Bruxelles: Kaléidoscope, 2008.

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Vardan, Lewon. Hin, hin baner. Pēyrutʻ: Hratarakutʻiwn Libananabnak Ayntʻaptsʻineru Hayrenaktsʻakan Miutʻean, 1997.

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Vardan, Lewon. Hin, hin baner. Pēyrutʻ: Hratarakutʻiwn Libananabnak Ayntʻaptsʻineru Hayrenaktsʻakan Miutʻean, 1997.

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Book chapters on the topic "Hib"

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Gooch, Jan W. "Hib Vaccine." In Encyclopedic Dictionary of Polymers, 898. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_13921.

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Dudley, Matthew Z., Daniel A. Salmon, Neal A. Halsey, Walter A. Orenstein, Rupali J. Limaye, Sean T. O’Leary, and Saad B. Omer. "Haemophilus Influenzae Type B (Hib)." In The Clinician’s Vaccine Safety Resource Guide, 39–44. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-94694-8_7.

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Slack, Mary P. E. "Haemophilus influenzae type b (Hib) Vaccines." In Pediatric Vaccines and Vaccinations, 171–81. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-59952-6_19.

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Slack, Mary P. E. "Haemophilus influenzae Type b (Hib) Vaccines." In Pediatric Vaccines and Vaccinations, 195–206. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-77173-7_19.

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Kawai, A., T. Fukushige, J. Makino, D. Sugimoto, and M. Taiji. "The PCI Interface for Grape Systems: PCI-HIB." In Astrophysics and Space Science Library, 233–37. Dordrecht: Springer Netherlands, 2001. http://dx.doi.org/10.1007/978-94-010-0864-8_26.

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Silfverdal, Sven Arne, Lennart Bodin, Marina Ulanova, Mirjana Hahn-Zoric, Lars Å. Hanson, and Per Olcén. "Antibody Response to Haemophilus Influenzae Type B (HIB) in Children with Invasive HIB Infection in Relation to Duration of Exclusive Breastfeeding." In Advances in Experimental Medicine and Biology, 311–13. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0559-4_60.

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Severin, W. P. J. "Zijn er rationele argumenten om vóór DKTP/HIB/BMR-vaccinatie te desinfecteren?" In Vademecum permanente nascholing huisartsen, 1860–61. Houten: Bohn Stafleu van Loghum, 2006. http://dx.doi.org/10.1007/978-90-313-8808-0_991.

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Gao, Jianwen, Gang Zhao, Gang Tang, Yong Xu, and Tao Xiong. "Study on primary recrystallisation annealing of 3% Si low temperature nitriding HiB steel." In Advances in Materials Science, Energy Technology and Environmental Engineering, 193–96. P.O. Box 11320, 2301 EH Leiden, The Netherlands, e-mail: Pub.NL@taylorandfrancis.com , www.crcpress.com – www.taylorandfrancis.com: CRC Press/Balkema, 2016. http://dx.doi.org/10.1201/9781315227047-37.

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Dankel, Simon Nitter. "3-Hydroxyisobutyrate (3-HIB): Features and Links as a Biological Marker in Diabetes." In Biomarkers in Diabetes, 1–12. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-81303-1_15-1.

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Dankel, Simon Nitter. "3-Hydroxyisobutyrate (3-HIB): Features and Links as a Biological Marker in Diabetes." In Biomarkers in Diabetes, 299–309. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-08014-2_15.

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Conference papers on the topic "Hib"

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Hoffmann, D. H. H., and J. Jacoby. "Status of HIB fusion in Europe." In Laser interaction and related plasma phenomena: 12th international conference. AIP, 1996. http://dx.doi.org/10.1063/1.50533.

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Someya, T., T. Kikuchi, K. Miyazawa, S. Kawata, and A. Ogoyski. "HIB Irradiation on a Direct-Driven Fuel Target in Heavy Ion Fusion." In IEEE Conference Record - Abstracts. 2005 IEEE International Conference on Plasma Science. IEEE, 2005. http://dx.doi.org/10.1109/plasma.2005.359208.

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Lima, Alan Gomes, and Mickie Takagi. "AVALIAÇÃO DO CRESCIMENTO DE HAEMOPHILUS INFLUENZAE TIPO B EM MEIO SÓLIDO ISENTO DE SANGUE DE CAVALO." In I Congresso de Engenharia de Biotecnologia. Revista Multidisciplinar de Educação e Meio Ambiente, 2021. http://dx.doi.org/10.51189/rema/1383.

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Introdução: A bactéria Haemophilus Influenzae tipo b (Hib) apresenta uma grande importância médica em todo mundo, pois, é causadora de diversas doenças, sendo mais agravante a meningite. A capsula polissacarídica que é composto por moléculas de poliribosil-ribitol-fosfato (PRP) é considerada como principal fator de virulência sendo utilizada como antígeno vacinal. Por ser considerada um microrganismo fastidioso, Hib necessita de condições especificas para seu crescimento, por esse motivo o meio solido amplamente utilizado é o Ágar chocolate, onde, adiciona-se sangue de cavalo, carneiro ou coelho em temperatura alta para que liberem compostos fundamentais para seu desenvolvimento. Com a crescente discussão sobre o uso de animais e seus componentes para estudos laboratoriais, a busca por alternativas que diminua o uso destes é extremamente importante, desse modo objetivo do presente estudo é avaliar a viabilidade célular de hib utilizando meio alternativo suplementado com fatores de crescimento NAD e Hemina; preparar o lote de trabalho utilizando o meio alternativo definido; quantificar a concentração de PRP obtida em frasco agitados. Material e métodos: O teste de viabilidade celular foi feito através da contagem do número de colônias viáveis que existem em 1 mL de amostra analisada expressa em UFC/mL; O teste de pureza da colônia foi feito através de Coloração de Gram; O acompanhamento do crescimento celular em meio líquido foi feito através da medida de Densidade Óptica em 540 nm (DO540); a determinação da concentração de PRP foi realizada através do método modificado de Bial (ASHWELL, 1957). Resultados: O meio solido suplementado proposto, proporcionou a manutenção da viabilidade celular em 1,4 x 1010 UFC/mL, muito similar a viabilidade atingida com o agar chocolate. Os ensaios em frascos agitados, em meio líquido apresentaram velocidade máxima específica de crescimento (µmax) de 0,515 h-1 e concentração de PRP na 8ª hora de cultivo de 360,9 mg/L de PRP reproduzindo aos ensaios cujo lote de trabalho fora realizado em agar chocolate. Conclusão: O meio sólido utilizado sem o uso de sangue de cavalo se mostrou eficiente para garantindo a viabilidade celular e a produção de PRP.
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Mannucci, Aldo, Ettore Anelli, Fabio Zana, Claudio Tommasi, Mariano Armengol, Laura Alleva, and Giorgio Porcu. "Bends for Critical Line Pipe Projects: Advantages of the Off-Line Full Quenching and Tempering." In ASME 2009 28th International Conference on Ocean, Offshore and Arctic Engineering. ASMEDC, 2009. http://dx.doi.org/10.1115/omae2009-79800.

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Recent trends for linepipe projects reflect a sustained increasing complexity: Sour Service (SS), High Temperature & High Pressure (HT/HP) field conditions, deep and ultra-deep water oil and gas transportation, Artic and Artic “alike” areas. This reflects into stringent requirements for manufacturing and testing of the concerned products, which are not only the straight pipes but also a number of accessories, among which bends are the ones presenting the most complex combination of critical issues. As long as a whole chain reliability standpoint is assumed as the main concern, the design, production and supply of the bends have become a key stage within a linepipe project. Bends for linepipe projects are produced in general by hot induction bending (HIB). Two different fabrication routes can be clearly identified: HIB followed by Stress Relieving (SR) and HIB followed by off-line full quenching and tempering (Q&T). The first method is known as “Traditional route (TR)”, while the second one as “Quenching-Tank (QT)”. A large investigation program was carried out involving the most recognised benders in Europe. The matrix of industrial trials comprised a dimensional size range from 168 to 406 mm OD, 8 to 34 mm WT; X60 to X70 steel grades, different bending and post-bending heat treatments conditions and mother pipe chemistries. For each analysed item, the final bend, the corresponding mother pipe and samples taken in as-bent / as-quenched (TR / QT) conditions were fully characterised in terms of mechanical properties, hardness profiles and microstructure features. As a result, a much better performance was found for the bends produced by the off-line full Q&T method, principally due to the better quenching efficiency with respect to the in-line system. Production of bends through out the traditional method can be seen as a reliable option for bends which are not going to face hard conditions in the field, and therefore the corresponding specification requirements are no stringent as well (i.e. X52 grade or lower, Charpy tests required at 0°C or higher temperature, no corrosion tests required, etc.). If either stringent conditions are required or X60-X80 steel grades are involved, the off-line quenching tank route becomes the reliable option.
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Costa, Anna Carolina Dockhorn de Menezes Carvalho, Lucas Dalvi Armond Rezende, Maria Gabriella Bianconi, Maxsuelen Rosa Da Silva Santos, and Gabriel Confalonieri Brtoldi Brtoldi. "O QUE HÁ DE EVIDÊNCIAS SOBRE PNEUMONIA ADQUIRIDA NA COMUNIDADE (PAC) EM CRIANÇAS: UMA REVISÃO DA LITERATURA EM MEIO À PANDEMIA DO COVID-19." In I Congresso Nacional de Microbiologia Clínica On-Line. Revista Multidisciplinar em Saúde, 2021. http://dx.doi.org/10.51161/rems/1203.

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Introdução: A pneumonia adquirida na comunidade (PAC) lidera as causas de mortes entre crianças menores de 5 anos no mundo todo, associada, ainda, a um mal diagnóstico pelos médicos. Isso tudo ainda num cenário de vacinação contra o Streptococcus pneumoniae e para Haemophilus influenzae tipo B (Hib). Ela pode ser causada tanto por vírus, quanto por bactérias, estas sendo secundárias à infecção viral em sua maioria. Material e Métodos: Realizou-se uma revisão integrativa de literatura na base de dados PubMed com os descritores conferidos no Medical Subjetics Headings (MeSH), sendo eles: “Community-Acquired Pneumonia” AND “Child” AND “Therapeutics”. Utilizou-se os filtros: texto completo disponível, intervalo temporal dos últimos 10 anos e artigos que correspondem a questão norteadora: “Quais as evidências científicas sobre o tratamento de PAC em crianças?”. Resultados: Os principais agentes da PAC achados foram o pneumococo e o Hib, contudo, mesmo com o advento das vacinas e esses patógenos controlados, ainda há grande mortalidade de crianças menores de cinco anos no mundo por PAC. O diagnóstico é majoritariamente clínico, podendo utilizar radiografias de tórax, sendo estas o padrão ouro, apresentando infiltrado pulmonar, tanto alveolar quanto intersticial, e a reação em cadeia de polimerase (PCR). O tratamento pode ser em meio hospitalar e ambulatorial. Quanto aos critérios de internação variam entre países desenvolvidos e subdesenvolvidos, sendo o tratamento de primeira linha para pneumonia bacteriana, amoxicilina via oral em pacientes ambulatoriais, e, para pacientes internados, ampicilina ou penicilina G ou amoxicilina, todos via intravenosa e para pacientes menores de 5 anos. O tratamento baseia-se no consenso mundial de que o patógeno Streptococcus pneumoniae é o agente mais comum em pacientes pediátricos Conclusão: Ainda há muita subestimação do quadro de PAC em crianças, com diagnósticos equivocados de síndromes gripais. No atual cenário global de pandemia do COVID-19, torna-se mais difícil de conseguir um diagnóstico eficaz devido às superlotações hospitalares e diminuição de recursos humanos. É imprescindível a setorização e manejo para que esses casos não se deteriorem e para que haja diminuição na mortalidade de crianças e neonatos.
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Miyahira, Clara Kimie, and Vania Maria Sabadoto Brienze. "Comparative analysis between the profile of cerebrospinal liquid (CSF) and clinical evolution in patients with bacterial meningitis." In XIII Congresso Paulista de Neurologia. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/1516-3180.023.

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Background: Bacterial meningitis is a serious infection that occurs in the Central Nervous System, which presents important morbidity and mortality, mainly in children. The main bacterial agents causing meningitis in the community are Haemophilus influenzae, Neisseria meningitidis and Streptococcus pneumoniae. Specific signs and symptoms suggest meningitis and cerebrospinal fluid analysis is the main exam leading to diagnosis. Objectives: To analyze the behavior of cerebrospinal fluid during the evolution of the patient with bacterial meningitis. Methods: A retrospective study revised the medical records of patients with bacterial meningitis confirmed by cerebrospinal fluid examination in the Base Hospital of São José do Rio Preto from January 1996 to December 2002. Results: in the 63 Patients, there were 18 cases (28.6%) of S. pneumoniae, 20 cases (31.7%) of H. influenzae, 12 cases (19%) of N.meningitides B and 13 (20.6%) cases of N. meningitidis C. In the 18 patients with pneumococcus, 10 (55.6%) were discharged and 8 (44.4%) died. In the 20 patients with HIB, only 3 (15%) died, there was no death patients with meningococcus B and C. Conclusion: There was no difference statistics in the cerebrospinal fluid of the patients who were discharged and those who died.
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Martinón-Torres, F., SA Halperin, T. Nolan, B. Tapiero, KP Perrett, IS de la Cueva, J. García-Sicilia, et al. "Immunantwort auf die DTPa-HBV-IPV/Hib-Auffrischimpfung bei Kleinkindern von Müttern, die während der Schwangerschaft mit Tdap-Impfstoff geimpft worden waren: Folgestudie einer randomisierten, placebokontrollierten Studie." In Kongressabstracts zur Tagung 2020 der Deutschen Gesellschaft für Gynäkologie und Geburtshilfe (DGGG). © 2020. Thieme. All rights reserved., 2020. http://dx.doi.org/10.1055/s-0040-1717189.

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Meschian, Moe, Andy Duncan, Matt Yarmuch, and Fred Myschuk. "An Investigation on Microstructural Evolution of X70 Steel Pipe During Hot Induction Bending." In 2018 12th International Pipeline Conference. American Society of Mechanical Engineers, 2018. http://dx.doi.org/10.1115/ipc2018-78018.

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It is generally accepted that hot induction bending (HIB) results in a decrease in strength and an increase in fracture toughness in bend area, heat affected zone (HAZ) and weld metal (WM). As the result, Post bend heat treatment (PBHT) is not considered to be a requirement and could be waived for saving money and time. This research work raises the concern that factual verification of proper microstructure and no localized brittle zone is vitally necessary prior to waving PBHT. Evaluation of the steel microstructure and mechanical properties as the result of various pipe chemistries during pipe bending has been verified in this experimental work. It is emphasized that knowledge and control of prior steel pipe chemistry, control of temperature, cooling rate and bending speed assures the reliability and repeatability of induction bends, especially in critical environments such as low temperature application. In the present work, qualitative and quantitative microstructural analysis, hardness and impact test performed and evaluated on samples from X70 line pipe with 3 different steel chemistries. The samples prepared from different locations on body, weld and HAZ in the as received and as bent condition. It was found that the final microstructure and mechanical properties in the as bent condition is dependent on the chemistry, steel cleanliness and microstructural uniformity. It was observed that small localized brittle zone with traces of upper Bainite and Martensite islands could be transformed in the microstructure with rich chemistry containing non-homogenous central segregation. It is concluded that factual verification of proper microstructure with no localized hard zone is required prior to waving PBHT.
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Widyaningsih, Vitri, and Bhisma Murti. "Antenatal Care and Provision of Basic Immunization in Children Aged 12-23 Months: Meta-Analysis." In The 7th International Conference on Public Health 2020. Masters Program in Public Health, Universitas Sebelas Maret, 2020. http://dx.doi.org/10.26911/the7thicph.03.125.

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ABSTRACT Background: Among the leading causes of global child morbidity and mortality are vaccine-preventable diseases, especially in low-and middle-income countries (LMICs). A complete basic immunization for children contains one BCG, three DPT-HB-Hib immunizations, four polio immunizations, and one measles immunizations. Antenatal care visit contributes an important to complete the basic immunization. This study aimed to estimate the effect of antenatal care on the completeness of basic immunization in children aged 12-23 months in Africa using meta-analysis. Subjects and Method: A meta-analysis and systematic review was conducted to examine the effect of antenatal care on the basic immunization completeness in children aged 12-23 months. Published articles in 2015-2020 were collected from PubMed and Google Scholar databases. Keywords used “immunization coverage” OR “vaccination coverage” OR “complete immunization” OR “complete vaccination” OR “full immunization” OR “full vaccination” AND children OR “child immunization” OR “child immunization coverage” NOT “incomplete immunization” OR “incomplete vaccination”. The inclusion criteria were full text, in English language, and using cross-sectional study design. The selected articles were analyzed by Revman 5.3. Results:6 studies from Senegal, Nigeria, Ethiopia, and South Africa showed that antenatal care increased basic immunization completeness in children aged 12-23 months (aOR=1.19; 95% CI= 1.06 to 1.36; p<0.001) with I2 = 95%). Conclusion: Antenatal care increases basic immunization completeness in children aged 12-23 months. Keywords: basic immunization, antenatal care, children aged 12-23 months Correspondence: Farida. Masters Program in Public Health, Universitas Sebelas Maret. Jl. Ir. Sutarmi 36A, Surakarta 57126, Central Java. Email: faridariza9232@gmail.com. Mobile: 085654415292 DOI: https://doi.org/10.26911/the7thicph.03.125
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Zheng, Jian-Wu, Jing Zhao, and Xin-Ping Guan. "Independent Delegation: Resolving Key Escrow Problem in HIBE and HIBS." In Computer Science and Technology 2016. Science & Engineering Research Support soCiety, 2016. http://dx.doi.org/10.14257/astl.2016.123.36.

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Reports on the topic "Hib"

1

Pinter, Abraham. HIV Vaccines Based on Novel MULV-HIV Fusion Proteins. Fort Belvoir, VA: Defense Technical Information Center, July 1999. http://dx.doi.org/10.21236/ada373677.

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2

Bingamon, Brian Michael. HIV Mosaic Vaccine. Office of Scientific and Technical Information (OSTI), December 2019. http://dx.doi.org/10.2172/1581247.

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3

Bae, Donal S., and Benjamin Shore. Pediatric Septic Hip. Touch Surgery Simulations, January 2016. http://dx.doi.org/10.18556/touchsurgery/2015.s0061.

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4

Kanki, Phyllis. Interactions of HIV-1 and HIV-2 in West Africa. Fort Belvoir, VA: Defense Technical Information Center, July 1999. http://dx.doi.org/10.21236/ada367779.

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Kanki, Phyllis. Interactions of HIV-1 and HIV-2 in West Africa. Fort Belvoir, VA: Defense Technical Information Center, July 1997. http://dx.doi.org/10.21236/ada329299.

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6

Kanki, Phyllis J. Interactions of HIV-1 and HIV-2 in West Africa. Fort Belvoir, VA: Defense Technical Information Center, October 2002. http://dx.doi.org/10.21236/ada416999.

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7

Goldstein, Neal. Epidemiology Blog of Neal D. Goldstein, PhD, MBI. Neal D. Goldstein, 2023. http://dx.doi.org/10.17918/goldsteinepi.

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Abstract:
Musings on topics related to epidemiology, epidemiological methods, public and clinical health. Written by Neal D. Goldstein, PhD, MBI. Dr. Goldstein is an Associate Professor of Epidemiology at the Drexel University Dornsife School of Public Health. With a background in biomedical informatics, he focuses on computational approaches in complex data settings, especially electronic health records and disease surveillance, to understand infectious disease transmission. This has been demonstrated through his work with blood borne pathogens (HIV and hepatitis C), COVID-19, vaccine preventable diseases, and healthcare associated infections.
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8

Camarillo, G., P. Nikander, J. Hautakorpi, A. Keranen, and A. Johnston. HIP BONE: Host Identity Protocol (HIP) Based Overlay Networking Environment (BONE). RFC Editor, January 2011. http://dx.doi.org/10.17487/rfc6079.

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9

Wilhoit, Juliana, Natalie Myers, and George Calfas. Data collection and management with ENSITE HUB: ENSITE HUB Version 1.0. Construction Engineering Research Laboratory (U.S.), September 2017. http://dx.doi.org/10.21079/11681/23050.

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10

Sood, Neeraj, and Yanyu Wu. The Impact of Insurance and HIV Treatment Technology on HIV Testing. Cambridge, MA: National Bureau of Economic Research, September 2013. http://dx.doi.org/10.3386/w19397.

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