Relevant bibliographies by topics / Heterocyclic compounds – Synthesis

Academic literature on the topic 'Heterocyclic compounds – Synthesis'

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Published: 4 June 2021
Last updated: 29 January 2023

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Journal articles on the topic "Heterocyclic compounds – Synthesis"

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Luna, Isadora Silva, Rayssa Marques Duarte da Cruz, Ryldene Marques Duarte da Cruz, Rodrigo Santos Aquino de Araújo, and Francisco Jaime Bezerra Mendonça-Junior. "1,4-Dithiane-2,5-diol: A Versatile Synthon for the Synthesis of Sulfur-containing Heterocycles." Current Organic Synthesis 15, no. 8 (December 17, 2018): 1026–42. http://dx.doi.org/10.2174/1570179415666180821154551.

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Background: 1,4-Dithiane-2,5-diol (1,4-DTD) is the stable dimer of α-mercapto acetaldehyde. This commercially available ambidentade compound is characterized as having in its chemical structure one group that acts as an electrophile and another that acts as a nucleophile, this permits its use as versatile and efficient synthon in synthetic heterocycle procedures. Objective: The aim of this review is to present synthetic applications of 1,4-DTD in heterocyclic chemistry and their applicability to the synthesis of bioactive compounds. Conclusion: Gewald reactions to obtain C-4 and C-5 unsubstituted 2-amino-thiophene derivatives; sulfa- Michael/Henry and sulfa-Michael/aldol sequences to obtain polysubstituted tetrahydrothiophenes, and other heterocyclic reactions that allow synthesizing several functionalized sulfur-containing heterocycles such as thiazolidines, oxathiazinoles and thiazoles are presented and discussed. The use of such heterocyclics in subsequent reactions allows obtaining various bioactive compounds including the antiretroviral lamivudine which is one of the examples presented in this review.
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Adak, Laksmikanta, and Tubai Ghosh. "Recent Progress in Iron-Catalyzed Reactions Towards the Synthesis of Bioactive Five- and Six-Membered Heterocycles." Current Organic Chemistry 24, no. 22 (December 18, 2020): 2634–64. http://dx.doi.org/10.2174/1385272824999200714102103.

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Heterocyclic compounds are the largely diverse organic molecules and find prevalent applications in the fine chemical industry, medicinal chemistry and agricultural science. They are also among the most commonly bearing frameworks in numerous drugs and pharmaceutical substances. Therefore, the development of convenient, efficient and environmentally benign methods to produce various types of heterocyclic compounds is an attractive area of research. For the synthesis and functionalization of heterocycles, enormous achievements have been attributed over the past decades. Recently, ironcatalyzed reactions have accomplished a noteworthy development in the synthesis of heterocycles. This review highlights some remarkable achievements in the iron-catalyzed synthesis of heterocyclic compounds published in the last five years.
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Murarka, Sandip, and Andrey Antonchick. "Metal-Catalyzed Oxidative Coupling of Ketones and Ketone Enolates." Synthesis 50, no. 11 (May 3, 2018): 2150–62. http://dx.doi.org/10.1055/s-0037-1609715.

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Recent years have witnessed a significant advancement in the field of radical oxidative coupling of ketones towards the synthesis of highly useful synthetic building blocks, such as 1,4-dicarbonyl compounds, and biologically important heterocyclic and carbocyclic compounds. Besides oxidative homo- and cross-coupling of enolates, other powerful methods involving direct C(sp3)–H functionalizations of ketones­ have emerged towards the synthesis of 1,4-dicarbonyl compounds. Moreover, direct α-C–H functionalization of ketones has also allowed an efficient access to carbocycles and heterocycles. This review summarizes all these developments made since 2008 in the field of metal-catalyzed/promoted radical-mediated functionalization of ketones at the α-position.1 Introduction2 Synthesis of 1,4-Dicarbonyl Compounds3 Synthesis of Heterocyclic Scaffolds4 Synthesis of Carbocyclic Scaffolds5 Conclusion
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Ābele, E., R. Ābele, Ļ. Golomba, J. Višņevska, T. Beresņeva, and K. Rubina. "Oximes of Seven-Membered Heterocyclic Compounds Containing One Heteroatom." Latvian Journal of Chemistry 50, no. 3-4 (January 1, 2011): 205–22. http://dx.doi.org/10.2478/v10161-011-0071-7.

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Oximes of Seven-Membered Heterocyclic Compounds Containing One Heteroatom Literature data on the synthesis and structure of azepane, oxepane and thiepane oximes were reviewed. Synthesis of novel heterocycles from oximes of seven-membered heterocycles containing one heteroatom were described. Biological activity of oximes of seven-membered heterocycles with one heteroatom was also reviewed.
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Ābele, E. "Oximes of Seven-Membered Heterocyclic Compounds Containing Two Heteroatoms." Latvian Journal of Chemistry 51, no. 1-2 (January 1, 2012): 83–92. http://dx.doi.org/10.2478/v10161-012-0005-z.

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Oximes of Seven-Membered Heterocyclic Compounds Containing Two Heteroatoms Literature data concerning the synthesis and structure of diazepane, oxazepane and thiazepane oximes were reviewed. Synthesis of novel heterocycles from the oximes of seven-membered heterocycles containing two heteroatoms was described. Biological activity of oximes of seven-membered heterocycles with two heteroatoms was also reviewed.
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Gupta, Vivek Kumar, Baljeet Kaur, Amandeep Kaur, Amanpreet Kaur, and Monika Gupta. "Synthesis and Biological Evaluation of 1,3,4-Oxadiazolyl benzenesulphonyl benzimidazole derivatives." Indian Journal of Pharmaceutical and Biological Research 6, no. 02 (June 30, 2018): 64–71. http://dx.doi.org/10.30750/ijpbr.6.2.10.

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Oxadiazoles are a class of heterocyclic aromatic chemical compound of azole family. Oxadiazole is five membered heterocycle having two carbons, two nitrogen, one oxygen and two double bonds. Oxadiazole exists in four isomeric forms depending upon the position of nitrogen atom in the ring. Benzimidazole is a heterocyclic aromatic compound. This bicyclic compound consists of fusion of benzene and imidazole. Benzimidazole may also be considered as cyclic analogues of imidines due to tautomerism effect. In the present study involves synthesis of1,3,4-oxadiazolyl benzenesulphonylbenzimidazole derivatives. All the synthesized compounds were screened against HepG-2 cell line to determine the growth inhibitory effect of compounds.All the synthesized compounds possessed good to moderate anti-cancer activity as compare to standard drug Adriamycin. Two of the synthesized compounds i.e. 8a and 8f were found to possess maximum anti-cancer activity.The structures of the synthesized compounds were established by IR and 1HNMR.
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Bakibayev, A. A., K. B. Zhumanov, S. Yu Panshina, S. I. Gorbin, V. S. Malkov, I. G. Tsoy, B. K. Massalimova, G. K. Matniyazova, and Е. А. Baybazarova. "Synthesis methods of phosphorylated carbamide containing acyclic and heterocyclic compounds." Bulletin of the Karaganda University. "Chemistry" series 95, no. 3 (September 30, 2019): 115–57. http://dx.doi.org/10.31489/2019ch3/115-157.

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Deng, Yongming, Qing-Qing Cheng, and Michael Doyle. "Asymmetric [3+3] Cycloaddition for Heterocycle Synthesis." Synlett 28, no. 14 (July 5, 2017): 1695–706. http://dx.doi.org/10.1055/s-0036-1588453.

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Asymmetric syntheses of six-membered ring heterocycles are important research targets not only in synthetic organic chemistry but also in pharmaceuticals. The [3+3]-cycloaddition methodology is a complementary strategy to [4+2] cycloaddition for the synthesis of heterocyclic compounds. Recent progress in [3+3]-cycloaddition processes provide powerful asymmetric methodologies for the construction of six-membered ring heterocycles with one to three heteroatoms in the ring. In this account, synthetic efforts during the past five years toward the synthesis of enantioenriched six-membered ring heterocycles through asymmetric [3+3] cycloaddition are reported. Asymmetric organocatalysis uses chiral amines, thioureas, phosphoric acids, or NHC catalysis to achieve high enantiocontrol. Transition-metal catalysts used as chiral Lewis acids to activate a dipolar species is an alternative approach. The most recent advance, chiral transition-metal-catalyzed reactions of enoldiazo compounds, has contributed toward the versatile and highly selective synthesis of six-membered heterocyclic compounds.1 Introduction2 Asymmetric Formal [3+3]-Cycloaddition Reactions by Organo­catalysis2.1 By Amino-Catalysis2.2 By N-Heterocyclic Carbenes2.3 By Bifunctional Tertiary Amine-thioureas2.4 By Chiral Phosphoric Acids3 Asymmetric Formal [3+3]-Cycloaddition Reactions by Transition-Metal Catalysis3.1 Copper Catalysis3.2 Other Transition-Metal Catalysis4 Asymmetric [3+3]-Cycloaddition Reactions of Enoldiazo Compounds4.1 Asymmetric [3+3]-Cycloaddition Reactions of Nitrones with Electrophilic Metallo-enolcarbene Intermediates4.2 Dearomatization in Asymmetric [3+3]-Cycloaddition Reactions of Enoldiazoacetates4.3 Asymmetric Stepwise [3+3]-Cycloaddition Reaction of Enoldiazoacetates with Hydrazones5 Summary and Outlook
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Mohareb, Rafat, and Hanaa Hana. "Synthesis of progesterone heterocyclic derivatives of potential antimicrobial activity." Acta Pharmaceutica 58, no. 1 (March 1, 2008): 29–42. http://dx.doi.org/10.2478/v10007-007-0043-3.

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Synthesis of progesterone heterocyclic derivatives of potential antimicrobial activityThe aim of this work was to synthesize steroidal heterocycles and to elucidate the potential role of these compounds as antimicrobial agents. The synthesis of steroidal heterocycles containing the pyrazole, isoxazole, thiazole, pyrane, pyridine, pyridazine, or benzopyrane ring attached to the pregnene nucleus is reported. Progesterone (1) reacts with dimethyl formamide dimethyl acetal to form enamine2. Heterocyclization of2with hydrazines, hydroxylamine, glycine, ethyl acetoacetate or cyanomethylene afforded novel steroidal heterocyclic derivatives. Thein vitroantimicrobial evaluation showed that all synthesized compounds show activity against the used strains of Gram positive bacteria and fungi.
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Journal, Baghdad Science. "Synthesis of some Heterocyclic Compounds Derived from." Baghdad Science Journal 10, no. 3 (September 1, 2013): 525–36. http://dx.doi.org/10.21123/bsj.10.3.525-536.

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The 4-(?-bromo acetyl)-4?-toluene sulfonanilide (2) was used as key intermediate to synthesize new heterocyclic compounds. This bromo compound was synthesized via sulfonation of amino group of p-amino acetophenone using Hinsburg method with 4-toluene sulfonyl chloride to form 4-acetyl-4?-toluene sulfonanilide (1) which is used as a starting material in this work. This compound was brominated to yield compound (2) which is used as a precursor to synthesize new five and seven membered heterocyclic compounds such as substituted 1,3-oxazoles (3,4), 1,3-thiazole derivatives (5-7), thiourea compounds (8a,b), 1,3-Thiazoline-2-thione compounds (9a-f) and 1,2,5-triazepine compounds (11a-d). The synthesized compounds were identified depending upon physical, FT-IR and UV spectroscopic data.
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Dissertations / Theses on the topic "Heterocyclic compounds – Synthesis"

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Wilson, Jennifer M. "Synthesis of biologically active heterocyclic compounds." Thesis, University of Glasgow, 2007. http://theses.gla.ac.uk/45/.

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More than 11 million people worldwide are diagnosed with cancer every year. New cancer drugs are required that are more effective and selective. Nitrogen mustard alkylating agents crosslink DNA inhibiting transcription and replication. Use of the mustard pharmacophore as part of a macrocycle allows metal complexation and produces a prodrug. Hypoxic tumour cells have increased concentrations of reductase enzymes which could lead to reduction of the complex in situ and release of a cytotoxic drug. Human African Trypanosomiasis is commonly known as Sleeping Sickness and affects over 36 countries of sub-Saharan Africa. It is transmitted to humans by the tsetse fly which carries the parasitic subspecies Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. Any compounds synthesised would also be tested to assess their potential as anti-parasitic agents. Parker synthesised a range of polyazamacrocycles. Testing of compound A in vitro gave highly efficient DNA crosslinking activity. Copper complexes were formed of the macrocycles and B was found to be 24 times more toxic against hypoxic cells than oxic cells thus exploiting tumour hypoxia and creating a selective drug. Jones synthesised a range of oxaazamacrocycles such as C which when tested in vitro exhibited comparable cross-linking activity to the azamacrocycles although it proved impossible to synthesise the corresponding copper complexes. It was decided to vary the leaving group on the alkylating arms to see if the DNA crosslinking results could be improved. Eight carbamates and the corresponding copper complexes were synthesised. The R-groups were alkyl and aromatic. Anti-cancer DNA crosslinking and hypoxia selectivity results were disappointing however, a number of compounds displayed significant activity when tested against T. brucei. A range of thiaazamacrocycles would complete the set of heteroatom-containing macrocycles (N, O, S) and might produce good DNA crosslinking results. It might also be possible to synthesise the corresponding copper complexes producing prodrugs. Six thiaazamacrocycles were synthesised and 2-hydroxyethyl arms were attached. However it proved impossible to isolate the desired alkylating agents with the 2-chloroethyl arms. In the body, the p53 protein activates the transcription of specific genes. In healthy cells, the levels of p53 have to be kept to a minimum to allow the normal running of the cell, e.g. growth and replication. This function is carried out by the HDM2 protein, which forms an auto-regulatory feedback loop with p53. In some tumours, the p53 function is disrupted due to genetic mutations of p53. However other tumours possess ‘wild type’ p53 – this type of p53 has lost the ability to respond to oncogenic stress due to over-expression of HDM2. Drugs that inhibit HDM2 should cause stabilisation of p53 and induce apoptosis in cancer cells. A small library of 5-deazaflavins were synthesised and biologically tested producing some interesting biological results.
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Jamalis, Joazaizulfazli. "Synthesis of heterocyclic containing oxygen compounds." Thesis, University of Bristol, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.529847.

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Emans, John. "Synthesis of novel heterocyclic polymers." Thesis, University of St Andrews, 1987. http://hdl.handle.net/10023/15299.

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This work details the synthesis, characterisation and fabrication of a range of copolyesters, containing various angular disrupters, especially disubstituted 2,5-diphenyl- -1,3,4-oxadiazoles. These disrupters were incorporated into the polymers, to reduce the temperature at which the polymers may be processed, to enable their fabrication into fibres. The majority of the polymers prepared were found to be liquid crystalline. However, if the angular disrupter content of the polymer was high, it was found that the resultant polymers were non-liquid crystalline. The polymers were prepared by a melt acidolysis process carried out under a nitrogen flow and subsequently under vacuum, as described in Chapter 3. Eighteen of the polymers were characterised in some detail, though a measure of the relative molecular weights was thought to be of little importance in this work, since all polymers were of a different composition. Differential scanning calorimetry and hot-stage microscopy revealed that several of the polymers had rather unusual melting behaviour. The eighteen polymers that were closely characterised were spun into fibres, using a small melt-spinning apparatus that was designed and produced by Bradford University Research Ltd, The resultant fibres were characterised by differential scanning calorimetry, X-ray diffraction end tensile testing. The general conclusion of the work is that although a reduction in the processing temperature of the polymer is achieved by the incorporation of angular disruptors, which is advantageous, the tensile strength and thermal stability of the fibres produced from such polymers are reduced.
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李安怡 and On-yi Lee. "Synthesis of heterocycles via phenylseleno group transfer radical cyclization and chemoselective reductive amination promoted by InCl3." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2007. http://hub.hku.hk/bib/B3955756X.

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Leu, Chao-Wei Chemistry Faculty of Science UNSW. "Synthesis of heterocyclic analogues of phytoestrogens." Publisher:University of New South Wales. Chemistry, 2008. http://handle.unsw.edu.au/1959.4/40824.

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The pyrrolo[3,2,1-ij]quinolin-6-one ring system was synthesised from 3-aryl-4,6-dimethoxyindoles and 2,3-disubstituted-4,6-dimethoxyindoles. The reaction of 4,6-dimethoxyindoles under Friedel-Crafts or Vilsmeier-Haack acylation gave the 2- and 7-indolyldeoxybenzoins in good yield. Cyclisation of 7-indolyldeoxybenzoins with N,N-dimethylformamide dimethyl acetal as a one carbon reagent gave the pyrroloquinolin-6-ones in high yield. Reduction of pyrroloquinolin-6-ones with hydrogen gas and 10% palladium on carbon or lithium aluminium hydride yielded the dihydropyrroloquinolin-6-ones. Demethylation of pyrroloquinolin-6-ones with 48% hydrobromic acid in glacial acetic acid gave a mixture of the monohydroxy and dihydroxy analogues in high yield. The synthesis of quinolin-4-ones using the Conrad-Limpach method was attempted using three different cyclisation conditions such as Dowtherm A, polyphosphoric acid and a mixture of diphenyl ether and methanesulfonic acid. Quinolin-2-ones such as 4-methyl-3-aryl-, 3,4-diaryl- and 3-aryl-4-benzyl-5,7-dimethoxyquinolin-2-ones could be synthesised from either the N-phenylacetylaniline or the N-trifluoroacetyl aniline strategy. Attempted reduction of the quinolin-2-ones with standard metal hydride reagents was unsuccessful. However reduction was achieved via the conversion of quinolin-2-one to the corresponding 2-chloroquinoline followed by reaction of the chloroquinoline with zinc powder and glacial acetic acid to produce a novel, highly substituted quinoline system. Demethylation was successfully carried out with 48% hydrobromic acid in glacial acetic acid to give the trihydroxyquinolin-2-one in high yield. The reactions of 4-substituted-5,7-dimethoxyquinolin-2-ones and the corresponding 2-chloroquinolines as potential organic intermediates were explored. Facile formylation of both quinolin-2-ones and 2-chloroquinolines was observed under Vilsmeier-Haack conditions while acetylation was successful under Friedel-Crafts conditions using antimony (V) pentachloride as the Lewis acid. Further reaction of 8-formyl-quinolin-2-one with 1,2-diaminobenzene in N,N-dimethylformamide led to the formation of a new 8-(benzimidazolyl)-quinolin-2-one ring system. The quinolin-2-ones exhibited selective electrophilic substitution at the C8 position for a range of reactions. However, an unexpected nitration occurred at the C3 position for the 4-methoxy and 4-phenyl-5,7-dimethoxyquinolin-2-ones with good yields. A series of novel 4,6-hydroxylindoles was successfully synthesised from the corresponding methoxy analogues in high yield using anhydrous aluminium chloride. When 3-(4-bromophenyl)-4,6-dimethoxyindole was reacted with 48% hydrobromic acid in glacial acetic acid a 2,2?-indolylindoline dimer was formed. The 5,7-dihydroxyquinolin-2-ones were similarly synthesised in high yield using anhydrous aluminium chloride in chlorobenzene.
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Burnett, Duane Arthur. "Synthesis of nitrogen containing heterocycles /." The Ohio State University, 1986. http://rave.ohiolink.edu/etdc/view?acc_num=osu1487264603219377.

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Khan, Musharraf Naveed. "Synthesis of different heterocyclic compounds of pharmaceutical relevance." Thesis, University of Huddersfield, 2013. http://eprints.hud.ac.uk/id/eprint/19503/.

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This thesis describes the synthesis of different cyclic imines and the exploration of their reactivity with cyclopropenones and 1,3-dipoles,as well as an investigation of the chemistry of the products. The synthesis of biologically and pharmaceutically important heterocyclic natural product analogues, such as the pyrroloazepines, indolizidines and pyrrolizidines has been achieved using a cycloaddition reaction between cyclic imidates and cyclopropenones. A new route to pyridines has been developed using the generation of a proposed 3-azacyclopentadienone as the key step. The 3-azacyclopentadienones are generated by using boiling toluene to induce a [2+2]-cycloreversion in a series of azabicyclo[3.2.0]hept-2-en-4- ones. Regiospecific Diels-Alder reaction of the intermediate 3-azacyclopentadienone with a styrene is followed by chelotropic extrusion of carbon monoxide and loss of hydrogen to give the pyridine. The process is similar to the well-known process by which benzenes are accessed from cyclopentadienones. The azabicyclo[3.2.0]hept-2 en-4-ones were available from the reaction of cyclopropenones with 1-azetines, where cyclopropenones behave as an all carbon 1,3- dipole equivalents. Using the same methodology 1,3-dipolar cycloaddition of nitrile oxides to 4-aryl-2-alkylthio-1-azetines afforded a series of oxadiazabicyclo[3.2.0]heptenes as single diastereoisomers. Heating these cycloadducts in toluene resulted in an overall [2+2]- cycloreversion to give 5-alkylthio-3-aryl-1,2,4 oxadiazoles. Cycloaddition reactions of a series of benzodiazepines were also studied. The benzodiazepines were formed using literature methods and converted to cyclic imines with the help of Meerwein’s reagent. Reactions between such cyclic imines and cyclopropenones and 1,3 dipoles were attempted to produce tricyclic and tetracyclic benzodiazepine analogues. Finally, some multicomponent reactions of aryl aldehydes with cyanides and 1,3-dicarbonyl compounds were investigated to produce fully substituted heterocyclic compounds like dihydropyridines and pyrans with substituents suitable for intramolecular cyclization and imine formation. The main substituent of interest was the azide group as this had been used in section 2.3.3.1.2 & 2.3.3.1.3 in this thesis.
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Stewart, Lesley Ann. "Synthesis of heterocyclic compounds as potential anticancer agents." Thesis, University of Glasgow, 1996. http://theses.gla.ac.uk/4936/.

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Taher, Abutariq. "Novel cyclisations of nitro-compounds for heterocyclic synthesis." Thesis, Loughborough University, 2001. https://dspace.lboro.ac.uk/2134/34705.

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The research described in this thesis is aimed at developing novel methods of synthesis for heterocyclic compounds, in particular cyclisation reactions involving the nitro functional group. The first chapter describes investigations into the Wallach imidazole synthesis. A number of chloroimidazoles were prepared, but the possible extension to highly functionalised imidazoles proved elusive. The second chapter describes studies on the successful conversion of nitroimidazolyl malonates 1 into imidazo[4,5-c]isoxazoles 2, Scheme 1. Related cyclisations are described in chapter three and the thiophene fused isoxazole 3 was successfully prepared. Chapter four investigates the reactivity of the strained imidazo[4,5-c]isoxazole heterocycles. Ring opening of the isoxazole occurred on reaction with phosphines to give iminophosphorane derivatives. Reactions with electron deficient acetylenes led to pyrrolyl imidazoles 4, and a novel [1,4]diazepino[2,3-c]isoxazole 5, Scheme 1, but no reaction was observed with alkenes. [Illustration omitted.] Chapter five entails synthesis of a series of 5-aryl-2H,1H-imidazo[4,5-d][1,2,3]triazole derivatives 7. Triethyl N-1-ethyl-2-methyl-4-nitro-1H-imidazol-5-yl phosphoramidate compound 6 was treated with a range of aryl isocyanates which gave imidazo[4,5-c]triazoles 7 in moderate to good yields. A mechanism involving carbodiimide formation was postulated and was supported using infra-red spectroscopy, Scheme 2. Chapter six reports a new synthesis of 5-aryl-2H indazole derivatives 9 by base catalysed reaction of 2-nitrobenzyl triphenylphosphonium bromide salts 8 with a range of aryl isocyanates. A mechanism of this reaction was proposed and investigated by infra-red spectroscopy, Scheme 3.
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Shirtcliff, Laura Donnell. "'Coarctate' cyclizations : applications to heterocycle synthesis /." view abstract or download file of text, 2006. http://proquest.umi.com/pqdweb?did=1188876631&sid=1&Fmt=2&clientId=11238&RQT=309&VName=PQD.

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Thesis (Ph. D.)--University of Oregon, 2006.
Typescript. Includes vita and abstract. Includes bibliographical references (leaves 336-357). Also available for download via the World Wide Web; free to University of Oregon users.
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Books on the topic "Heterocyclic compounds – Synthesis"

1

Ellis, G. P. Synthesis of fused heterocycles. Chichester [Sussex]: Wiley, 1987.

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A, Silling S., and Zaikov Gennadiĭ Efremovich, eds. Synthesis and properties of heterocyclic compounds. Huntington, N.Y: Nova Science Publishers, 2001.

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1956-, Nylund Kristian, and Johansson Peder 1945-, eds. Heterocyclic compounds: Synthesis, properties, and applications. Hauppauge, N.Y: Nova Science Publishers, 2009.

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P, Nolan Steven, ed. N-Heterocyclic carbenes in synthesis. Weinheim: Wiley-VCH, 2006.

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Fluorinated heterocyclic compounds: Synthesis, chemistry, and applications. Hoboken, N.J: Wiley, 2009.

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Patel, Ramesh. Triazines: Synthesis, applications, and toxicity. Hauppauge, N.Y: Nova Science Publishers, 2011.

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C, Palmer David, ed. Oxazoles: Synthesis, reactions, and spectroscopy. Hoboken, N.J: Wiley, 2003.

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Ellis, G. P. Synthesis of fused heterocycles : Part 2. Chichester [Sussex]: Wiley, 1992.

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Rusanov, A. L. Aromatic polyethers based on heterocyclic monomers. Hauppauge, N.Y: Nova Science Publishers, 2010.

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Vicario, Jose L., Dolores Badia, and Luisa Carrillo. New methods for the asymmetric synthesis of nitrogen heterocycles 2005. Kerala, India: Research Signpost, 2005.

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Book chapters on the topic "Heterocyclic compounds – Synthesis"

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Tabaković, Ibro. "Anodic synthesis of heterocyclic compounds." In Topics in Current Chemistry, 87–139. Berlin, Heidelberg: Springer Berlin Heidelberg, 1997. http://dx.doi.org/10.1007/3-540-61454-0_71.

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Ata, Athar, and Samina Naz. "Synthesis of Bioactive Heterocyclic Compounds." In Greener Synthesis of Organic Compounds, Drugs and Natural Products, 137–50. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9781003089162-8.

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Rathore, Deepshikha, Geetanjali, and Ram Singh. "Enzyme-Mediated Synthesis of Heterocyclic Compounds." In Advances in Green Synthesis, 277–88. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-67884-5_16.

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Yamamoto, Yoshihiko, and Kenji Itoh. "Ruthenium-Catalyzed Synthesis of Heterocyclic Compounds." In Ruthenium Catalysts and Fine Chemistry, 249–76. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/b94646.

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Joule, J. A., K. Mills, and G. F. Smith. "Saturated and partially unsaturated heterocyclic compounds: reactions and synthesis." In Heterocyclic Chemistry, 463–78. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4899-3222-8_26.

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Miles, Dillon H., and F. Dean Toste. "Enantioselective Gold-Catalyzed Synthesis of Heterocyclic Compounds." In Topics in Heterocyclic Chemistry, 227–48. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/7081_2015_5003.

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Hoffmann, Reinhard W., Achim Hense, Ingo Münster, Jochen Krüger, David Brückner, and Vincent J. Gerusz. "Synthesis of Heterocyclic Compounds by Allylboration Reactions." In ACS Symposium Series, 160–75. Washington, DC: American Chemical Society, 2001. http://dx.doi.org/10.1021/bk-2001-0783.ch012.

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Norman, Richard, and James M. Coxon. "The synthesis of five-and six-membered heterocyclic compounds." In Principles of Organic Synthesis, 676–727. Dordrecht: Springer Netherlands, 1993. http://dx.doi.org/10.1007/978-94-011-2166-8_21.

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Barba, Fructuoso. "Electrosynthesis of Heterocyclic Compounds and Other Alternative Electrosynthetic Processes." In Novel Trends in Electroorganic Synthesis, 271–74. Tokyo: Springer Japan, 1998. http://dx.doi.org/10.1007/978-4-431-65924-2_82.

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Race, Nicholas J., and John F. Bower. "Synthesis of Heteroaromatic Compounds by Alkene and Enyne Metathesis." In Topics in Heterocyclic Chemistry, 1–32. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/7081_2015_145.

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Conference papers on the topic "Heterocyclic compounds – Synthesis"

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Redda, Kinfe Ken, Madhavi Gangapuram, Mohammad A. Ghaffari, Suresh Eyunni, Nelly Mateeva, and Bereket Mochona. "Abstract 2229: Synthesis of heterocyclic compounds as anticancer agents." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-2229.

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El Fattah, M. E. Abd, H. H. Abd Allah, and A. H. Soliman. "Synthesis and Biological Activity of Some New Heterocyclic Compounds." In The 14th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2010. http://dx.doi.org/10.3390/ecsoc-14-00495.

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Haddad, Batool S., and Mariam Abdul-bary. "Synthesis of new Azo compounds combining with heterocyclic groups." In International Conference of Chemistry and Petrochemical Techniques (ICCPT). AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0093536.

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Glukhacheva, Vera, and Sergey Ilꞌyasov. "SYNTHESIS AND PROPERTIES OF NITRO DERIVATIES OF HETEROCYCLIC ANTRACENES." In Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m729.aks-2019/97-99.

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Stanovnik, Branko. "3-Dimethylaminopropenoates and Related Compounds in the Synthesis of Heterocyclic Systems and Heterocyclic Amino Acids." In The 4th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2000. http://dx.doi.org/10.3390/ecsoc-4-01783.

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Drokin, R., D. Gazizov, D. Tiufiakov, E. Voinkov, E. Gorbunov, E. Ulomsky, G. Rusinov, and V. Rusinova. "POTASSIUM SALTS OF NITROCARBONYL COMPOUNDS IN THE SYNTHESIS OF NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS." In Chemistry of nitro compounds and related nitrogen-oxygen systems. LLC MAKS Press, 2019. http://dx.doi.org/10.29003/m749.aks-2019/187-189.

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Marinescu, Maria, Maria Antonia Tănase, Ludmila-Otilia Cinteză, Ioana Cătălina Gȋfu, Sabina Georgiana Burlacu, and Cristian Petcu. "Synthesis and Nonlinear Optical Studies of N-Containing Heterocyclic Compounds." In Priochem 2021. Basel Switzerland: MDPI, 2022. http://dx.doi.org/10.3390/chemproc2022007039.

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Pyrko, A. N. "ENVIRONMENTALLY FRIENDLY SYNTHESIS AND BIOLOGICAL TESTING FOR PESTICIDAL ACTIVITY OF HETEROCYCLIC ANALOGS OF STEROIDS." In SAKHAROV READINGS 2022: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY. International Sakharov Environmental Institute of Belarusian State University, 2022. http://dx.doi.org/10.46646/sakh-2022-1-187-190.

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Abstract:
The aim of the study is the synthesis and testing for pesticidal activities of 2,3-dimethoxy-16,16-dimethyl-D-homo-8-azagona-1,3,5 (10),13-tetraene-12,17а-one and 2,3-dimethoxy-16,16-dimethyl-d-homo-8-azagona-1,3,5(10),13-tetraene-12-imino-17а-one hydrochloride which could become the basis of plant protection products. The first compound was obtained by condensation of 6,7-dimethoxy-2,3-dihydroisoquinoline with 2-acetyl-5.5-dimethylcyclohexane-1,3-dione. The second substance was synthesized by interaction of the first with ammonium chloride. The synthesized compounds were tested for certain types of pesticide activities. Both synthesized compounds showed herbicidal activity against amaranthus retroflexus, brassica rapa, abutilon theophrasti and insecticidal activity against toxoptera graminum. Hydrochloride 2,3-dimethoxy-16,16-dimethyl-D-homo-8-azagon-1,3,5(10),13-tetraene-12-imino-17a-one showed insecticidal activity against musca domestica and fungicidal activity against drechslera.
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AL-Khazraji, Shaima Ibraheem Chyad. "Synthesis and characterization of some heterocyclic compounds derived from 2-mercapto benzothiazole." In INTERNATIONAL CONFERENCE OF NUMERICAL ANALYSIS AND APPLIED MATHEMATICS ICNAAM 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0027534.

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Obaid, Ehab K., Rahmah H. Abdullah, Hussein Abdulkadim Hasan, Najlaa N. Hussein, Maha A. Khalaf, and Ali Jabbar Radhi. "Synthesis and study biological activity of new heterocyclic compounds based on sugar." In INTERNATIONAL CONFERENCE OF NUMERICAL ANALYSIS AND APPLIED MATHEMATICS ICNAAM 2019. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0027867.

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