Relevant bibliographies by topics / Heterocyclic

Academic literature on the topic 'Heterocyclic'

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Published: 4 June 2021
Last updated: 10 March 2023

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Journal articles on the topic "Heterocyclic"

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Luna, Isadora Silva, Rayssa Marques Duarte da Cruz, Ryldene Marques Duarte da Cruz, Rodrigo Santos Aquino de Araújo, and Francisco Jaime Bezerra Mendonça-Junior. "1,4-Dithiane-2,5-diol: A Versatile Synthon for the Synthesis of Sulfur-containing Heterocycles." Current Organic Synthesis 15, no. 8 (December 17, 2018): 1026–42. http://dx.doi.org/10.2174/1570179415666180821154551.

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Background: 1,4-Dithiane-2,5-diol (1,4-DTD) is the stable dimer of α-mercapto acetaldehyde. This commercially available ambidentade compound is characterized as having in its chemical structure one group that acts as an electrophile and another that acts as a nucleophile, this permits its use as versatile and efficient synthon in synthetic heterocycle procedures. Objective: The aim of this review is to present synthetic applications of 1,4-DTD in heterocyclic chemistry and their applicability to the synthesis of bioactive compounds. Conclusion: Gewald reactions to obtain C-4 and C-5 unsubstituted 2-amino-thiophene derivatives; sulfa- Michael/Henry and sulfa-Michael/aldol sequences to obtain polysubstituted tetrahydrothiophenes, and other heterocyclic reactions that allow synthesizing several functionalized sulfur-containing heterocycles such as thiazolidines, oxathiazinoles and thiazoles are presented and discussed. The use of such heterocyclics in subsequent reactions allows obtaining various bioactive compounds including the antiretroviral lamivudine which is one of the examples presented in this review.
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Winne, Johan, Jan Hullaert, Bram Denoo, Mien Christiaens, and Brenda Callebaut. "Heterocycles as Moderators of Allyl Cation Cycloaddition Reactivity." Synlett 28, no. 18 (July 27, 2017): 2345–52. http://dx.doi.org/10.1055/s-0036-1588511.

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For the rapid elaboration of polycarbocyclic scaffolds, prevalent in many important families of terpenoid natural products, allyl cations derived from simple heterocyclic alcohols can be used as versatile reaction partners in both (4+3) and (3+2) cycloaddition pathways. Our recent progress in this area is outlined, pointing towards the untapped potential of heterocycles to act as reagents in novel or known but challenging organic transformations.1 Heterocyclic Reagents2 Cycloadditions and Allyl Cations3 Furfuryl Cations in Cycloadditions4 Heterocycle-Substituted Cations in Cycloadditions5 Mechanistic Considerations6 Conclusions and Outlook
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Andres, C. J., Derek J. Denhart, Milind S. Deshpande, and Kevin W. Gillman. "Recent Advances in the Solid Phase Synthesis of Drug Heterocyclic Small Molecules." Combinatorial Chemistry & High Throughput Screening 2, no. 4 (August 1999): 191–210. http://dx.doi.org/10.2174/1386207302666220204193145.

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Abstract: Because of their synthetic challenge, broad range of physical I chemical properties, and diverse biological activities, heterocycles continue to be of interest to both the academic and industrial chemist. This review covers recent advances in the solid phase synthesis of drug-like heterocyclic small molecules. Syntheses which form the heterocycle on the solid phase are emphasized; syntheses in which a preformed heterocycle is functionalized on the solid support have been omitted. The majority of references are from publication year 1999. This review should be of interest to anyone involved in, or contemplating the solid phase synthesis of small molecule drug-like heterocycles, especially for combinatorial chemistry applications.
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Bhattacharya, Somenath, Soumallya Chakraborty, Rohan Pal, Sourav Saha, Bhaskar Ghosh, Chiranjit Mandal, Dr Amitava Roy, and Dr Arin Bhattacharjee. "A Comprehensive Review on Pyrazole and It’s Pharmacological Properties." International Journal for Research in Applied Science and Engineering Technology 10, no. 9 (September 30, 2022): 1769–74. http://dx.doi.org/10.22214/ijraset.2022.46924.

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Abstract: Heterocyclic chemistry is very important aspects in organic chemistry. Heterocyclic system consists of one or more heteroatoms like nitrogen, oxygen, sulphur, etc with hydrogen atoms. The system can be classified as saturated as well as non saturated system or hydrocarbons. Another classification of this ring system is divided in some categories like three-membered, four-membered, five-membered, six-memebered, seven-membered, fused heterocyclics etc. Some compounds under this cklassification are acidic or basic in nature. Examples of heterocyclic compounds are Pyrole, Furan, Thiophene, Pyridine, Quinoline, Isoquinoline, Indole, Purine, Pyrazole, etc. Pyrazole is very important under this heterocyclic ring sysyem. Pyrazole is five membered heterocyclics. Pyrazole is basic and unsaturated in nature due to presence of double bonds in their ring structure. When two nitrogen atoms are associated with five menbered heterocyclic ring in 1,2 positions called as Pyrazole structure. It is also known as 1,2-diazole. It is present in many drugs as well as organic compounds and Pharmaceutical compounds. The review study shown that the structure, physical and chemical properties, nomenclature, synthetic approaches, biological activities of Pyrazole heterocyclic ring structure
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Yadav, Shailendra, Sushma Singh, and Chitrasen Gupta. "A CONCISE OVERVIEW ON HETEROCYCLIC COMPOUNDS EXHIBITING PESTICIDAL ACTIVITIES." International Journal of Advanced Research 9, no. 08 (August 31, 2021): 989–1004. http://dx.doi.org/10.21474/ijar01/13352.

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Heterocyclic compounds are numerous and diverse group of organic compounds. Heterocycles are abundantly found in nature and express various physiological properties. Heterocycles are intricately linked to all aspects of life. There are many heterocyclic compounds currently known, and the number is constantly rising owing to extensive synthetic development and their applications. Heterocyclic compounds are used significantly in a number of areas, including biochemistry and medicinal chemistry, and some others. They are predominantly synthesized in agrochemical and pharmaceutical industries due to their potential biological activities. This review article focuses on recently synthesized heterocyclic compounds and their different pesticidal activities such as antifungal, antibacterial, antiviral, nematocidal, insecticidal, acaricidal, and herbicidal.
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Palaniappan, Saravana Priya. "Pharmacological Role of Heterocyclic Compounds in the Treatment of Alzheimer’s Disease: A Review." Journal of Phytopharmacology 11, no. 4 (August 15, 2022): 289–94. http://dx.doi.org/10.31254/phyto.2022.11412.

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Alzheimer’s disease (AD) is a multifactorial neurological disease that mainly affects the old age people. Neuropathologically, AD is characterized by low level of acetylcholine, loss of synapses and neurons in certain brain regions, accumulation of extracellular amyloid beta peptide (Aβ) and phosphorylation of intracellular tau protein. Patients with AD are characterized by various symptoms such as memory deficits, depression, cognitive dysfunction and difficult to perform daily activities. Currently available drugs for the treatment of AD are used to treat symptomatic relief at an early stage, however the prolonged usage of the drugs may cause adverse side effects. To overcome this, development of drugs produced from natural products is considered as one of the promising alternatives for the treatment of AD. Among that heterocyclic compound play a major role in the development of therapeutic drugs against various disorders. An organic compound which is cyclic or non-cyclic consists of one or more atoms in their ring structure are known as heterocyclic compounds. These heterocyclic compounds occur both in natural and synthetic form and play a major role in the metabolism of all living cells. Most of the organic compounds used as drugs have a heterocyclic core in their skeleton. Nitrogenous bases such as purines and pyrimidines present in DNA, chlorophyll, vitamins contain heterocycle in their structure. Other compounds containing heterocycles are proline, morphine, furan, vinblastine, cephalosporin, penicillin etc. This review summarizes the nomenclature, classification, and the role of heterocyclic compounds in the treatment of Alzheimer's disease.
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Munzeiwa, Wisdom A., Bernard Omondi, and Vincent O. Nyamori. "Architecture and synthesis of P,N-heterocyclic phosphine ligands." Beilstein Journal of Organic Chemistry 16 (March 12, 2020): 362–83. http://dx.doi.org/10.3762/bjoc.16.35.

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Diverse P,N-phosphine ligands reported to date have performed exceptionally well as auxiliary ligands in organometallic catalysis. Phosphines bearing 2-pyridyl moieties prominently feature in literature as compared to phosphines with five-membered N-heterocycles. This discussion seeks to paint a broad picture and consolidate different synthetic protocols and techniques for N-heterocyclic phosphine motifs. The introduction provides an account of P,N-phosphine ligands, and their structural and coordination benefits from combining heteroatoms with different basicity in one ligand. The body discusses the synthetic protocols which focus on P–C, P–N-bond formation, substrate and nucleophile types and different N-heterocycle construction strategies. Selected references are given in relation to the applications of the ligands.
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Zhu, Yannan, and You Huang. "Organocatalyzed [3+3] Annulations for the Construction of Heterocycles." Synthesis 52, no. 08 (February 5, 2020): 1181–202. http://dx.doi.org/10.1055/s-0039-1690810.

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Six-membered heterocyclic systems are widely distributed in many natural products and pharmaceuticals, and the construction of highly functionalized six-membered heterocyclic compounds is an important topic in modern organic synthesis. Organocatalyzed [3+3] annulations represents an important method for assembling a substantial variety of six-membered cycles that contain one or more heteroatoms. This review describes the development of organocatalyzed [3+3] annulations for the synthesis of six-membered heterocycles, including organocatalysis using secondary amines, tertiary amines, phosphines, chiral phosphoric acids and N-heterocyclic carbenes.1 Introduction2 Secondary Amine Catalyzed [3+3] Annulations2.1 Synthesis of Nitrogen Heterocycles2.2 Synthesis of Oxygen Heterocycles2.3 Synthesis of Sulfur Heterocycles3 Tertiary Amine Catalyzed [3+3] Annulations3.1 Catalysis through Multiple Hydrogen-Bonding Interactions3.2 Catalysis of Tertiary Amines as Lewis Bases4 Phosphine-Catalyzed [3+3] Annulations4.1 Synthesis of Nitrogen Heterocycles4.2 Synthesis of Oxygen Heterocycles4.3 Synthesis of Heterocycles Containing Two or More Heteroatoms5 Chiral Phosphoric Acid Catalyzed [3+3] Annulations5.1 Synthesis of Nitrogen Heterocycles5.2 Synthesis of Heterocycles Containing Two or More Heteroatoms6 N-Heterocyclic Carbene Catalyzed [3+3] Annulations6.1 Synthesis of Nitrogen Heterocycles6.2 Synthesis of Oxygen Heterocycles6.3 Synthesis of Heterocycles Containing Two or More Heteroatoms7 Conclusion and Outlook
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Shaikh, Ansar R., Mazahar Farooqui, R. H. Satpute, and Syed Abed. "Overview on Nitrogen containing compounds and their assessment based on ‘International Regulatory Standards’." Journal of Drug Delivery and Therapeutics 8, no. 6-s (December 21, 2018): 424–28. http://dx.doi.org/10.22270/jddt.v8i6-s.2156.

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Heterocyclic compounds have a role in most fields of sciences such as medicinal chemistry, biochemistry also another area of sciences. More than 90% of new drugscontain heterocycles and the interface between chemistry and biology, at which so much new scientific insight, discovery and application is taking place is crossed by heterocyclic compounds. Compounds derived from heterocyclic rings in pharmacy, medicine, agriculture, plastic, polymer and other fields.Most active heterocycles that have shown considerable biological actions as antifungal, anti-inflammatory, antibacterial, anticonvulsant, antiallergic, herbicidal, anticancer activity. There is always a strong need for new and efficient processes in synthesizing of new Heterocycles.Alum have been used as a novel catalyst in the synthesis of Schiff’s bases. Synthesized Schiff’s bases are free from use of ICH class 1 and Class 2 solvents and also free from structural alerts genotoxic impurities. This review highlights on various aspects of heterocyclic compounds with its biological activity & regulatory assessment based on the ‘International Regulatory Standards’. Keywords: Heterocycles. Nitrogen containing compounds Biological activity, History, Regulatory assessment, International Regulatory Standards
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Ábrányi-Balogh, Péter, Aaron Keeley, György G. Ferenczy, László Petri, Tímea Imre, Katarina Grabrijan, Martina Hrast, et al. "Next-Generation Heterocyclic Electrophiles as Small-Molecule Covalent MurA Inhibitors." Pharmaceuticals 15, no. 12 (November 29, 2022): 1484. http://dx.doi.org/10.3390/ph15121484.

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Heterocyclic electrophiles as small covalent fragments showed promising inhibitory activity on the antibacterial target MurA (UDP-N-acetylglucosamine 1-carboxyvinyltransferase, EC:2.5.1.7). Here, we report the second generation of heterocyclic electrophiles: the quaternized analogue of the heterocyclic covalent fragment library with improved reactivity and MurA inhibitory potency. Quantum chemical reaction barrier calculations, GSH (L-glutathione) reactivity assay, and thrombin counter screen were also used to demonstrate and explain the improved reactivity and selectivity of the N-methylated heterocycles and to compare the two generations of heterocyclic electrophiles.
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Dissertations / Theses on the topic "Heterocyclic"

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Locke, Julie Myree, University of Western Sydney, College of Health and Science, and School of Biomedical and Health Sciences. "Synthetic and conformational studies of hexahydropyrimidines and related heterocycles." THESIS_CHS_BHS_Locke_J.xml, 2003. http://handle.uws.edu.au:8081/1959.7/638.

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This thesis explores the synthesis and conformational behaviour of hexahydropyrimidines and related heterocycles, with particular emphasis on 5- hyrdohexahydropyrimidines. The conformational behaviour of these compounds was investigated using dynamic NMR spectroscopy, molecular modelling techniques and X-ray crystal structure analysis. The conformational behaviour of 5- hyrdohexahydropyrimidine, hexahydropyrimidine and their analogous oxygen compounds as well as a series of hexahydropyrimidines with various exocyclic substituents, were examined. The preferred conformations of all these compounds are attenuated by a combination of steric and electronic influences. These influences include intramolecular hydrogen bonding as well as anomeric and gauche interactions. The conformational behaviour of the selected seven membered benzodiazepine rings, which share structural characteristics with the six-membered 5- hyrdohexahydropyrimidines was also explored. The increased flexibility of the seven membered rings facilitates intramolecular hydrogen bonding, which in turn retards ring inversion in these systems
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Lewis, William. "Chiral Heterocyclic Ligands." Thesis, University of Canterbury. Chemistry, 2007. http://hdl.handle.net/10092/1383.

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This thesis describes the preparation and characterisation of a number of homochiral coordination and metallosupramolecular assemblies. These species were formed from the reaction of chiral pyridine and quinoline containing ligands and metal ions. The combination of traditional coordination chemistry and supramolecular interactions led to a range of polymeric and network structures being formed. The ligands used in this thesis can be divided into two broad categories: alkaloids and ligands derived from them, and amino acid-based ligands. In the first category three new ligands were synthesized, and a variety of routes towards alkaloid-based homochiral ligands were investigated. The second category focused on three ligand motifs, and resulted in the preparation of 16 ligands. These two categories of ligands were reacted with a range of metal salts to investigate their coordination and supramolecular chemistry. The structure of twenty complexes was determined by single crystal X-ray crystallography. The complexes had a range of structures, with discrete and polymeric species being formed. Hydrogen bonding was an important feature in the supramolecular chemistry of the complexes, playing a different role in different series of complexes. Two chiral coordination polymers and one chiral coordination network were synthesized. All three of these structures possessed directionality to some degree: in the coordination network and one of the polymers the directionality is counterbalanced by the opposite directionality being present in the crystal, while the second coordination polymer is generated by the screw axis present and has a high degree of overall directionality.
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Civcir, Pervin Unal. "Extended heterocyclic systems." Thesis, University of East Anglia, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.332359.

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Karatza, Mary-Helen. "Extended heterocyclic systems." Thesis, University of East Anglia, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359850.

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Collier, Steven James. "Heterocyclic ortho-quinodimethanes." Thesis, University of Liverpool, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.366249.

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White, Lindsay Anne. "Heterocyclic o-quinodimethanes." Thesis, University of Liverpool, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.262608.

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Liu, Jing. "Heterocyclic small molecule peptidomimetics." [College Station, Tex. : Texas A&M University, 2008. http://hdl.handle.net/1969.1/ETD-TAMU-3125.

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Myers, Eddie Leonard. "Heterocyclic aromatic nucleic acids." Thesis, McGill University, 2002. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=79056.

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In order to investigate the role played by the aromatic moiety of Aromatic Peptide Nucleic Acids (APNAs) in their ability to hybridize with RNA and DNA, as well as improve the solubility of APNA oligomers in aqueous solutions, a new generation of heterocyclic monomers were designed. APNA monomers, where the nucleobase can be thymine, cytosine adenine or guanine, with backbones contain thiophene and pyridine moieties were synthesized. Suitably protected APNA-APNA and PNA-APNA dimers were also synthesized as building blocks for the solid phase synthesis of APNA-PNA chimeras and APNA homopolymers. Due to the instability of the pyridine-containing APNA oligomers to the harsh acidic conditions required to cleave oligomers from the MBHA resin, a new protocol was developed for the synthesis of these molecules on the trityl chloride resin. Oligomers of PNA and APNA-PNA chimeras were successfully synthesized on this solid support, and cleaved from the resin using mild acidic conditions.
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Jones, Richard G. "Studies in heterocyclic synthesis." Thesis, University of Nottingham, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.238268.

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Chauncey, Marek Anthony. "Reactions heterocyclic quinone methides." Thesis, University of Ulster, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328193.

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Books on the topic "Heterocyclic"

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Abel, E. W., ed. Heterocyclic Chemistry. Cambridge: Royal Society of Chemistry, 2007. http://dx.doi.org/10.1039/9781847551061.

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(Keith), Mills K., and Knovel (Firm), eds. Heterocyclic chemistry. 4th ed. Malden, MA: Blackwell Science, 2000.

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Suschitzky, H., and O. Meth-Cohn, eds. Heterocyclic Chemistry. Cambridge: Royal Society of Chemistry, 1985. http://dx.doi.org/10.1039/9781847556325.

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Suschitzky, H., ed. Heterocyclic Chemistry. Cambridge: Royal Society of Chemistry, 1986. http://dx.doi.org/10.1039/9781847556332.

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Gupta, Radha Raman, Mahendra Kumar, and Vandana Gupta. Heterocyclic Chemistry. Berlin, Heidelberg: Springer Berlin Heidelberg, 1999. http://dx.doi.org/10.1007/978-3-662-07757-3.

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Gupta, Radha Raman, Mahendra Kumar, and Vandana Gupta. Heterocyclic Chemistry. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-72276-9.

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Joule, J. A., K. Mills, and G. F. Smith. Heterocyclic Chemistry. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4899-3222-8.

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Gilchrist, T. L. Heterocyclic chemistry. Harlow, Essex, Eng: Longman Scientific & Technical, 1989.

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K, Mills, ed. Heterocyclic chemistry. 4th ed. Malden, MA: Blackwell Science, 2000.

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(Keith), Mills K., ed. Heterocyclic chemistry. 5th ed. Hoboken, N.J: Wiley, 2009.

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Book chapters on the topic "Heterocyclic"

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Sahar, Amna, Ubaid ur Rahman, Muhammad Issa Khan, and Muhammad Azam Khan. "Heterocyclic Amines." In Food Safety, 89–111. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-39253-0_5.

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John, Kaarthik. "Heterocyclic Amines." In Encyclopedia of Cancer, 1–7. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27841-9_2693-2.

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Gupta, Radha Raman, Mahendra Kumar, and Vandana Gupta. "Heterocyclic Synthesis." In Heterocyclic Chemistry, 159–273. Berlin, Heidelberg: Springer Berlin Heidelberg, 1998. http://dx.doi.org/10.1007/978-3-642-72276-9_5.

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John, Kaarthik. "Heterocyclic Amines." In Encyclopedia of Cancer, 2066–72. Berlin, Heidelberg: Springer Berlin Heidelberg, 2017. http://dx.doi.org/10.1007/978-3-662-46875-3_2693.

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Gooch, Jan W. "Heterocyclic Compound." In Encyclopedic Dictionary of Polymers, 364. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_5914.

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Gooch, Jan W. "Heterocyclic Monomers." In Encyclopedic Dictionary of Polymers, 364. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-6247-8_5915.

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Shi, Xueliang, and Chunyan Chi. "Heterocyclic Quinodimethanes." In Topics in Current Chemistry Collections, 169–207. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-93302-3_4.

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Thomson, R. H. "N-Heterocyclic quinones." In Naturally Occurring Quinones IV, 583–649. Dordrecht: Springer Netherlands, 1997. http://dx.doi.org/10.1007/978-94-009-1551-0_5.

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Nelson, David J., and Steven P. Nolan. "N-Heterocyclic Carbenes." In N-Heterocyclic Carbenes, 1–24. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2014. http://dx.doi.org/10.1002/9783527671229.ch01.

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FRANTA, E., and L. REIBEL. "Cationic Heterocyclic Polymerization." In ACS Symposium Series, 183–94. Washington, D.C.: American Chemical Society, 1985. http://dx.doi.org/10.1021/bk-1985-0286.ch014.

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Conference papers on the topic "Heterocyclic"

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Torroba, Tomas, Oleg Rakitin, and Charles Rees. "New heterocyclic materials." In The 4th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2000. http://dx.doi.org/10.3390/ecsoc-4-01781.

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Stanovnik, Branko. "3-Dimethylaminopropenoates and Related Compounds in the Synthesis of Heterocyclic Systems and Heterocyclic Amino Acids." In The 4th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2000. http://dx.doi.org/10.3390/ecsoc-4-01783.

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Schnell, Barbara, and Thomas Kappe. "Sulfidation of Heterocyclic 1,3-Dicarbonyl Systems ." In The 3rd International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 1999. http://dx.doi.org/10.3390/ecsoc-3-01720.

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Šíbor, Jiří, and Aleš Bárta. "NEW WAYS OF HETEROCYCLIC CHEMISTRY TEACHING." In 12th International Technology, Education and Development Conference. IATED, 2018. http://dx.doi.org/10.21125/inted.2018.1210.

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Manabe, S., H. Yanagisawa, S. Ishikawa, Y. Kitagawa, K. Tohyama, S. Abe, and O. Wada. "TRYPTOPHAN PYROLYSIS PRODUCTS FOUND IN COOKED FOODS INHIBIT HUMAN PLATELET AGGREGATION BY INHIBITING CYCLOOXYGENASE." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643402.

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Humans are exposed to numerous toxic compounds in foods. During the past decade, several carcinogenic heterocyclic amines have been reported to be present in the cooked foods. Recently, we reported that some of the carcinogenic heterocyclic amines isolated from foods were present in human plasma. In order to know the effects of the carcinogens isolated from foods on the cell function, we investigated the effects of the carcinogenic heterocyclic amines including Trp-P-1(3-amino-l,4-dimethyl-5H-pyrido❘4,3-b❘indole) and Trp-P-2(3-amino-1-methyl-5H-pyrido❘4,3-b❘indole) on human platelet aggregation and polymorphonuclear leukocyte aggregation. Only tryptophan pyrolysis products, Trp-P-1 and Trp-P-2, had potent inhibitory effects on human platelet aggregation when platelets were preincubated with the carcinogens for 15 min. Other carcinogenic heterocyclic amines such as glutamic acid pyrolysates (Glu-P-1 and Glu-P-2) and 3H-imidazo ❘4,5-f❘quinoline-2-amines(IQ and MelQ) did show no effect on platelet aggregation even at 100 μM.The autoradiogram demonstrated that Tryptophan pyrolysis products, Trp-P-1 and Trp-P-2, dose-dependently inhibited the formation of HHT,PGD2,PGE2 and TXB2 induced by sodium arachidonate in human platelets labeled with ❘ 14c❘ arachidonic acid. Moreover, Trp-P-1 and Trp-P-2 did not show significant effects on leukocyte aggregation induced by sodium arachidonate (0.75mM) even at lOOnM. It is concluded that Trp-P-1 and Trp-P-2 isolated from cooked foodstuffs have potent inhibitory effects on the cyclo-oxygenase pathway of the platelet. Therefore, human platelet function might be affected with daily foods containing tryptophan pyrolysis products in vivo.
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Wolfe, James F. "Rigid Aromatic Heterocyclic Polymers For Nonlinear Optics." In 30th Annual Technical Symposium, edited by Garo Khanarian. SPIE, 1987. http://dx.doi.org/10.1117/12.939640.

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Maiboroda, D. A., V. V. Scherbukhin, and E. V. Babaev. "Computer design of heterocyclic ring-opening reactions." In The first European conference on computational chemistry (E.C.C.C.1). AIP, 1995. http://dx.doi.org/10.1063/1.47787.

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Ha, Sie-Tiong, Guan-Yeow Yeap, Teck-Leong Lee, and Teck-Ming Koh. "New Heterocyclic Liquid Crystals with Benzothiazole Core." In The 14th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2010. http://dx.doi.org/10.3390/ecsoc-14-00373.

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Nowak, Kacper, Michal Grzelczak, Boguslaw Szlachetko, Piotr Swiatek, Malgorzata Strzelecka, Lukasz A. Sterczewski, Edward F. Plinski, and Stanislawa Plinska. "Terahertz investigations on some bi-heterocyclic compounds." In 2016 21st International Conference on Microwave, Radar and Wireless Communications (MIKON). IEEE, 2016. http://dx.doi.org/10.1109/mikon.2016.7492097.

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Pausch, Axel E., Thomas Geelhaar, Eike Poetsch, and Ulrich Finkenzeller. "New fluorinated heterocyclic compounds for improved FLC mixtures." In SPIE/IS&T 1992 Symposium on Electronic Imaging: Science and Technology, edited by Paul S. Drzaic and Uzi Efron. SPIE, 1992. http://dx.doi.org/10.1117/12.60381.

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Reports on the topic "Heterocyclic"

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Allcock, Harry R. Strained Inorganic Heterocyclic Compounds and their Conversion to Macrocycles and High Polymers. Fort Belvoir, VA: Defense Technical Information Center, October 1991. http://dx.doi.org/10.21236/ada241414.

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Pagoria, P., and A. Racoveanu. Trinitromethyl Heterocyclic Oxidizers as a Solid Propellant Ingredient Final Report CRADA No TC02146.0. Office of Scientific and Technical Information (OSTI), August 2017. http://dx.doi.org/10.2172/1417952.

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Klubek, B. Microbial removal of organic sulfur from coal (bacterial degradation of sulfur-containing heterocyclic compounds). Office of Scientific and Technical Information (OSTI), March 1990. http://dx.doi.org/10.2172/7019091.

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Parshikov, Igor. Microbial Transformation of Some Ethylpyridines by Fungi. Intellectual Archive, January 2022. http://dx.doi.org/10.32370/iaj.2635.

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Abstract:
We were observed transformation 4-ethylpyridine and 2-methyl-5-ethylpyridine by fungus Beauveria bassiana ATCC 7159. Stereoselective oxidation of methylene group leading to the optically active (-)-(1-hydroxyethyl)pyridine was shown. Besides, the hydroxylation of methyl groups and the oxidation of the heterocyclic ring in the nitrogen atom to the respective primary alcohols and N-oxides were observed
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Bogen, Kenneth. PSA-Based Screening Outcomes, Dietary Heterocyclic Amine Exposure, and Prostate Cancer Risk in African-Americans. Fort Belvoir, VA: Defense Technical Information Center, January 2006. http://dx.doi.org/10.21236/ada448532.

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Keating, Garrett A. PSA-Based Screening Outcomes, Dietary Heterocyclic Amine Exposure, and Prostate Cancer Risk in African Americans. Fort Belvoir, VA: Defense Technical Information Center, June 2008. http://dx.doi.org/10.21236/ada504067.

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Bogen, Kenneth T. PSA-Based Screening Outcomes, Dietary Heterocyclic Amine Exposure, and Prostate Cancer Risk in African Americans. Fort Belvoir, VA: Defense Technical Information Center, January 2007. http://dx.doi.org/10.21236/ada466696.

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Hong, Jun-Yan. Inter-Individual Variation in the Metabolic Activation of Heterocyclic Amines and Susceptibility to Prostate Cancer. Fort Belvoir, VA: Defense Technical Information Center, July 2005. http://dx.doi.org/10.21236/ada470103.

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Pagoria, P., and A. Racoveanu. Synthesis of a Novel Energetic Heterocyclic Oxidizer with Higher Energy and Lower Sensitivity Final Report CRADA No. TC02099.0. Office of Scientific and Technical Information (OSTI), September 2017. http://dx.doi.org/10.2172/1396220.

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Pagoria, P. F., and A. Racoveanu. Synthesis of a Novel Energetic Heterocyclic Oxidizer with Higher Energy and Lower Sensitivity (Phase 2) Final Report CRADA No. TC02125.0. Office of Scientific and Technical Information (OSTI), September 2017. http://dx.doi.org/10.2172/1396235.

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You might also be interested in the extended bibliographies on the topic 'Heterocyclic' for particular source types:
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