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1

Li, Hui, and Yan Zheng. "Herbal Materials Warehouse Environment Monitoring System." Applied Mechanics and Materials 329 (June 2013): 8–12. http://dx.doi.org/10.4028/www.scientific.net/amm.329.8.

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In recent years, the efficacy of Chinese herbal medicines decreases often because of bad storage. It carries huge economic losses, furthermore, it endangers the safety of people's lives. Therefore, it is an urgent need for a new monitoring concepts and monitoring system for medicine warehouse to overcome many shortcomings. Combining the wireless sensor network technology, we researched environment parameter detection system of Chinese herbal medicine storage with a reasonable structure. It can monitor the air temperature, humidity, light, and water content parameters of herbs storage environment. We designed the hardware, software and interactive interface of the monitoring system. The proposed system has a better real-time and more accurate compared with the traditional manual monitoring system.
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Bagaeva, K., Yu Hakimova, A. Uriev, and B. Efremov. "Continuous cutting beams herbal raw materials." Актуальные направления научных исследований XXI века: теория и практика 3, no. 6 (December 8, 2015): 67–71. http://dx.doi.org/10.12737/16392.

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3

Parham, Shokoh, Anousheh Zargar Kharazi, Hamid Reza Bakhsheshi-Rad, Hadi Nur, Ahmad Fauzi Ismail, Safian Sharif, Seeram RamaKrishna, and Filippo Berto. "Antioxidant, Antimicrobial and Antiviral Properties of Herbal Materials." Antioxidants 9, no. 12 (December 21, 2020): 1309. http://dx.doi.org/10.3390/antiox9121309.

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Recently, increasing public concern about hygiene has been driving many studies to investigate antimicrobial and antiviral agents. However, the use of any antimicrobial agents must be limited due to their possible toxic or harmful effects. In recent years, due to previous antibiotics’ lesser side effects, the use of herbal materials instead of synthetic or chemical drugs is increasing. Herbal materials are found in medicines. Herbs can be used in the form of plant extracts or as their active components. Furthermore, most of the world’s populations used herbal materials due to their strong antimicrobial properties and primary healthcare benefits. For example, herbs are an excellent material to replace nanosilver as an antibiotic and antiviral agent. The use of nanosilver involves an ROS-mediated mechanism that might lead to oxidative stress-related cancer, cytotoxicity, and heart diseases. Oxidative stress further leads to increased ROS production and also delays the cellular processes involved in wound healing. Therefore, existing antibiotic drugs can be replaced with biomaterials such as herbal medicine with high antimicrobial, antiviral, and antioxidant activity. This review paper highlights the antibacterial, antiviral, and radical scavenger (antioxidant) properties of herbal materials. Antimicrobial activity, radical scavenger ability, the potential for antimicrobial, antiviral, and anticancer agents, and efficacy in eliminating bacteria and viruses and scavenging free radicals in herbal materials are discussed in this review. The presented herbal antimicrobial agents in this review include clove, portulaca, tribulus, eryngium, cinnamon, turmeric, ginger, thyme, pennyroyal, mint, fennel, chamomile, burdock, eucalyptus, primrose, lemon balm, mallow, and garlic, which are all summarized.
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Dewi, Mayang Kusuma, Anis Yohana Chaerunisaa, Muhaimin Muhaimin, and I. Made Joni. "Improved Activity of Herbal Medicines through Nanotechnology." Nanomaterials 12, no. 22 (November 18, 2022): 4073. http://dx.doi.org/10.3390/nano12224073.

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Phytochemicals or secondary metabolites are substances produced by plants that have been shown to have many biological activities, providing a scientific basis for using herbs in traditional medicine. In addition, the use of herbs is considered to be safe and more economical compared to synthetic medicine. However, herbal medicines have disadvantages, such as having low solubility, stability, and bioavailability. Some of them can undergo physical and chemical degradation, which reduces their pharmacological activity. In recent decades, nanotechnology-based herbal drug formulations have attracted attention due to their enhanced activity and potential for overcoming the problems associated with herbal medicine. Approaches using nanotechnology-based delivery systems that are biocompatible, biodegradable, and based on lipids, polymers, or nanoemulsions can increase the solubility, stability, bioavailability, and pharmacological activity of herbals. This review article aims to provide an overview of the latest advances in the development of nanotechnology-based herbal drug formulations for increased activity, as well as a summary of the challenges these delivery systems for herbal medicines face.
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Raina, M. K. "EMERGING TRENDS IN QUALITY CONTROL OF HERBAL MATERIALS." INDIAN DRUGS 55, no. 08 (August 28, 2018): 5–6. http://dx.doi.org/10.53879/id.55.08.p0005.

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The therapeutic use of medicinal plants gained considerable momentum in the world during the past few decades. Traditional medicines, which are mostly based on the herbal raw materials growing in their respective regions, were used by over 70 percent of the world population as per WHO. The reason for their popularity was due to non-availability of modern medicines in the rural areas and also due to the unaffordability of modern medicines due to their high cost. Quality control of medicinal plants for use in these Traditional medicines has always been a challenge for the scientists working in this field. In our country, with the awareness growing among the people about the safety of Ayurvedic and Herbal medicines / cosmetics, the quality control testing of both raw herbal ingredients and finished formulations was seriously undertaken both by the academic / research institutions and the herbal drug manufacturers.
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Kuz’menko, A. N. "Application of gas-liquid chromatography for standardization of herbal raw materials and herbal drugs." Russian Journal of General Chemistry 82, no. 3 (March 2012): 595–601. http://dx.doi.org/10.1134/s1070363212030395.

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7

Setyowati, Nuning, Rhina Uchyani Fajarningsih, and Raden Kunto Adi. "ANALISIS POTENSI DAN STRATEGI PENGEMBANGAN JAMU INSTAN DI KABUPATEN KARANGANYAR." Caraka Tani: Journal of Sustainable Agriculture 27, no. 1 (September 11, 2017): 63. http://dx.doi.org/10.20961/carakatani.v27i1.14356.

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<p>This study aims to map the agro-rural instant herbal medicine in Karanganyar District, identifying rank (potential) of rural agro instant herbal medicine in the District of Karanganyar, formulating development strategies agroindusti rural development strategy and identify herbal instant maps of rural agro-industry business chain instant herbal medicine in the District of Karanganyar. The research method using descriptive analytical method, the technique of collecting data using surveys and focus group techniques. Analysis tools used include: Comparative Exponential Method, Borda method, SWOT and Value Chain. The results showed that the agro-instant herbal medicine spread in Jatipuro, Jenawi, Jumantono, Karanganyar, Kerjo, Mojogedang and Tawangmangu sub district. Instant herbal medicine al agroindustry is ranked second seed. Instant herbal medicine development strategy include: Increasing the ability of producers in diversifying the instant herbal products at affordable prices the market, increase market access for instant herbal product diversification, increase access to capital through access to financing institutions, development of product diversification while maintaining product quality, increase the ability of producers in access to quality raw materials at affordable prices, increase product quality with local raw materials, especially in terms of capital Strengthening of procurement of raw materials, and development of business partnerships in terms of procurement of raw materials. Business actors in the agroindustry are instant herbal-medicinal and medicinal farmers market vendors as suppliers of raw materials, manufacturers and marketers are as pengolahnya herbal merchants.</p>
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Ha, Wai-Yan, Ka-Lok Wong, Wai-Yee Ma, Yuk-Yu Lau, and Wing-Han Chan. "Enhancing Testing Laboratory Engagement in Plant DNA Barcoding through a Routine Workflow—A Case Study on Chinese Materia Medica (CMM)." Plants 11, no. 10 (May 16, 2022): 1317. http://dx.doi.org/10.3390/plants11101317.

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Introduction of DNA standards into Pharmacopoeia in different parts of the world enables identification of herbal materials in a complementary manner. However, little has been discussed about the quality requirements for a testing laboratory to implement DNA barcoding methods for herbal materials, which has limited the test method to be developed as a routine service. To encourage the engagement of testing laboratory in application of DNA barcode, a practical workflow including the components of analytical run and the corresponding quality control plan was suggested and employed to address a real-life challenge faced by the differentiation of plant-derived Chinese Materia Medica (CMM), Herba Potentillae Chinensis (Wei ling Cai), Herba Potentillae Discoloris (Fan Bai Cai), Radix Pulsatillae (Bai Tou Weng), and Radix Arnebiae (Zi Cao), which share similar morphological characteristics and multiple species involved. The ITS2 barcode results indicated that there are significant differences among the four CMM, together with quality control plan data to ensure the measurement traceability and validity of test results.
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Hu, Chun-di, Xiao-ru Li, Lian-fang Yu, Guang-wei Xu, Shao-yin Liu, and Yi-zeng Liang. "Analysis of volatile components in herbal pair herba schizonepetae-ramulus cinnamomi." Journal of Central South University of Technology 15, no. 6 (December 2008): 791–95. http://dx.doi.org/10.1007/s11771-008-0146-0.

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Mazur-Pączka, Anna, Mariola Garczyńska, Grzegorz Pączka, and Joanna Kostecka. "APPLIED BOTANY. II. ACQUISITION OF CHOSEN HERBAL MATERIALS." Inżynieria Ekologiczna 18, no. 4 (August 1, 2017): 184–89. http://dx.doi.org/10.12912/23920629/74957.

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11

Lai, Wing-Fu, and Andrey L. Rogach. "Hydrogel-Based Materials for Delivery of Herbal Medicines." ACS Applied Materials & Interfaces 9, no. 13 (March 23, 2017): 11309–20. http://dx.doi.org/10.1021/acsami.6b16120.

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12

LI, Ming, Hui CAO, Paul Pui-Hay BUT, and Pang-Chui SHAW. "Identification of herbal medicinal materials using DNA barcodes." Journal of Systematics and Evolution 49, no. 3 (May 2011): 271–83. http://dx.doi.org/10.1111/j.1759-6831.2011.00132.x.

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13

Samali, A., Florence D. Tarfa, K. B. Mustapha, Nneka N. Ibekwe, and O. P. Adigwe. "Variability of Heavy Metal Content of Phytomedicine from Foreign and Local Source Sold in Nigeria." Journal of Phytomedicine and Therapeutics 21, no. 1 (August 17, 2022): 747–53. http://dx.doi.org/10.4314/jopat.v21i1.2.

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The popularity of herbal products has been on increase throughout the world; but one major challenge facing it is lack of guaranteed safety with respect to heavy metals contamination. In this study, Chinese, Indian and Nigerian phytomedicine were evaluated for Copper (Cu), Cadmium (Cd), Lead (Pb) and Zinc (Zn) in order to ascertain and compare their safety or level of contamination. The samples were purchased, processed and analyzed using Flame Atomic Absorption Spectrometer (FAAS). The results obtained were presented as mean concentrations of Cu, Cd, Pb and Zn in the Nigerian, Chinese and Indian phytomedicine as 1.23±0.03μg/g, 5.46±0.04μg/g, 5.16±0.01μg/g (Cu), 2.07±0.04μg/g, 9±0.06μg/g, 6.28±0.03μg/g (Cd), 4.42±0.18μg/g, 7.74±0.07μg/g, 5.05±0.06μg/g (Pb) and 2.90±0.04μg/g, 6.40±0.04μg/g, 2.53±0.04μg/g (Zn) respectively. The results indicated all the Nigerian herbal remedies analyzed and 33.33% of the Chinese and Indian herbal remedies contained cadmium above WHO permissible limit (0.3 μg/g) for herbals. The analysis of variance (ANOVA) results obtained at p-value 95% (p ˂ 0.050) ranges from significant to non-significant difference of means among the three countries. The correlation coefficient (r) also ranges from negative to strong degree of association. The variability of the heavy metals content could be associated to geographical, environmental, anthropogenic factors and heavy metals absorption potentials of the medicinal plants used. Environmental monitoring of herbal materials is required in order to ensure their safety from chemical pollutants that could lead to bio-accumulation of heavy metals in herbal materials.
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Pitri, Rina Muhayah Noor. "PEMANFAATAN TUMBUHAN HUTAN SEBAGAI BAHAN BAKU UNIT USAHA JAMU DAN PENGOLAHAN BAHAN ALAM DI KALIMANTAN SELATAN." EnviroScienteae 12, no. 3 (December 10, 2016): 338. http://dx.doi.org/10.20527/es.v12i3.2458.

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The existence of forest plants have been the source of traditional medicine for local communities. The use of natural materials by local communitiies as part of the medicinal treatment is done for subsistence. Not many identifiable utilization of the forest plants to meet the needs of business units herbal raw materials and processing of natural materials. This study seeks to identify the utilization of forest plants as raw material for herbal medicine business unit and the processing of natural materials in South Kalimantan. Mapping the distribution of the manufacturing herbal and natural ingredients also conducted and analyzed its association with the presence of the plant and within the forest. Data is collected using semi-structured interview to further analyzed descriptively. The collection of layers that constitute thematic information for the analysis of Geographic Information Systems. GIS analysis using ArcView 3.3 software. The results showed that the mixture dipterocarp forest is a forest type that is the source material for herbal medicine business unit and the processing of natural materials in South Kalimantan. The business unit is the most widely used natural materials from the forest is the micro and small (≤ 50%) or medium sized business units are relatively few industries using natural materials from the forest (± 10%). The distribution of herbal medicine business unit and the processing of natural materials in South Kalimantan uneven. Herbal medicine business unit and the processing of natural materials is also limited to the city of Banjarmasin, Martapura, Banjarbaru, Amuntai, Barabai. Distance to the forest as a source of raw materials and distribution of herbal industry/processing of natural materials not correlate significantly. The rapid development of urban economy and cultural factors related to the presence of viscous processing units herbal and natural ingredients.
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Sienkiewicz, Aneta, Alicja Piotrowska-Niczyporuk, and Andrzej Bajguz. "Herbal Industry Wastes as Potential Materials for Biofuel Production." Proceedings 51, no. 1 (July 15, 2020): 6. http://dx.doi.org/10.3390/proceedings2020051006.

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Due to the increasing awareness of the depletion of fossil fuel resources and environmental issues, biodiesel as alternative fuel has become more and more attractive in the recent years. In this research, the characterization of herbal industry wastes as a potential feedstock for biodiesel production was carried out. There results of analytical identification of the fatty acid methyl esters (FAME) obtained in the transesterification reaction are presented. The reaction conditions were optimized, considering hexane ratio and catalyst concentration (methanol and KOH) for both steps. The FAME were extracted from the herbal samples by ultrasound-assisted extraction and subsequently were identified by gas chromatography-mass spectrometry (GC-MS) using single ion monitoring (SIM) method. Additionally, the selected properties of some bioesters were analyzed. This study determined the compounds which are ideal for fuel production. The unsaturated fatty acids were found in higher amounts than saturated fatty acids. Linoleic acid (C18:2n6c) was the major unsaturated fatty acid in herbal wastes, while palmitic acid (16:0) was the major saturated fatty acid. The application of the optimized method also revealed differences in the physical and chemical properties of isolated FAME mixtures compared to conventional diesel fuel. In this research work, for the first time, the possibilities of using the herbal industry wastes as a potential feedstock for biodiesel production are assessed.
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Pavlova, E. V., D. I. Udavliev, T. G. Putina, and S. S. Shihov. "VETERINARY AND SANITARY ASSESSMENT OF SAFETY DRY HERBAL TEA." Problems of Veterinary Sanitation, Hygiene and Ecology 1, no. 2 (2020): 196–204. http://dx.doi.org/10.36871/vet.san.hyg.ecol.202002012.

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For safety of herbal teas for consumers, the veterinary and sanitary expertise of plant raw materials and finished goods including definition of the content of heavy metals, microbiological indicators, mycotoxins, pesticides according to requirements of Technical regulations of the Customs union 021/2011 "About safety of food products" has to be carried out. Data of veterinary and sanitary examination of 50 samples of multicomponent herbal teas on the normalized indicators are provided. The assessment of risk of contamination of herbal raw materials and herbal teas by pathogenic microorganisms and microorganism activators of damage of raw materials and products is carried out. All packed herbal tea samples conformed to the requirements fixed by the existing standards. The maintenance of mold fungi in herbal tea rooibos with cinnamon in 021% of samples from 2011 no more than 48 exceeded the normalized quantity, by 10…100 times. Mold fungi have been provided by not toxicogenic types of Alternaria, Penicillium, Cladosporium. The maintenance of aflatoxin did not exceed norm in all studied samples of herbal teas. Stability at storage of herbal tea depends on quantity and species composition of residual microflora. The raised maintenance of mold fungi of activators of damage can lead to reduction of expiration date of herbal tea.
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Sari, Lusia Oktora Ruma Kumala. "Pemanfaatan Obat Tradisional Dengan Pertimbangan Manfaat Dan Keamanannya." Pharmaceutical Sciences and Research 3, no. 1 (April 2006): 1–7. http://dx.doi.org/10.7454/psr.v3i1.3394.

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Herbal medicines in general are safer than modern drug. This matter is caused by the less side effect of herbal medicines than modern drug. Side effects of herbal medicines can be reduced with the used of right materials, accurat dose, accurat usage time, accurat way of usage, accurat analyze information, and without abusing of herbal medicines itself. Accuracy of materials determine the effect of herbal medicines. Dose measuring in set of gram can lessen possibility the happening of effect which do not be expected. Information which is not supported by adequate basic knowledges and enough study can make traditional drug return to endangering.
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Gamage, Dehel Gamage Nadeeshani Dilhara, Rathnayaka Mudiyanselage Dharmadasa, Don Chandana Abeysinghe, Rathnayaka Gamlathge Saman Wijesekara, Gamika A. Prathapasinghe, and Takao Someya. "Emerging Herbal Cosmetic Production in Sri Lanka: Identifying Possible Interventions for the Development of the Herbal Cosmetic Industry." Scientifica 2021 (March 10, 2021): 1–12. http://dx.doi.org/10.1155/2021/6662404.

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Although the herbal cosmetic industry has exponentially increased globally, manufacturing of herbal cosmetic products in Sri Lanka is still very limited. Therefore, objectives of the study were to recognize plants used in commercialized herbal cosmetic products and major constraints faced by herbal cosmetic manufacturers and to identify possible interventions for the development of herbal cosmetic industry of Sri Lanka. Information was gathered via a semistructured questionnaire by personal interviews with 11 large-scale multiple herbal cosmetic products manufacturers. Collected data were analyzed via frequency index for usage and descriptive statistics. A total of 115 plant species belonging to 56 families were identified. Extensive usage of Aloe vera (L.) Burm.f., Coscinium fenestratum (Goetgh.) Colebr., and Santalum album L. (90.91%) was reported among herbal cosmetic manufacturers. The highest number of plants or plant materials was used for manufacturing skin care products (54.78%) followed by hair care (19.13%) and oral care (6.96%). The majority of plants were reported from the plant family Fabaceae (16 species). Leaves (20.87%) were the widely used plant part, whereas 10 plant species were used as whole plants. Inadequacy of 7 plants/plant materials and importation of 8 plant materials for the production were also recognized. As major constraints faced by herbal cosmetic manufacturers, inadequate availability and poor quality of raw materials were emphasized. In conclusion, establishing proper cultivation system, implementing strategies for quality control of raw materials, and conducting ethnobotany, ethnopharmacological surveys to identify cosmetic potential of medicinal plants and partnerships with universities to transfer technology for product development to industries are possible interventions for the development of herbal cosmetic industry of Sri Lanka.
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Rajeshwari, Puttaswamy, and KoteshwarAnandrao Raveesha. "MYCOLOGICAL ANALYSIS AND AFLATOXIN B1CONTAMINANT ESTIMATION OF HERBAL DRUG RAW MATERIALS." African Journal of Traditional, Complementary and Alternative Medicines 13, no. 5 (August 12, 2016): 123–31. http://dx.doi.org/10.21010/ajtcam.v13i5.16.

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Background: The present study explores the fungal contamination of important herbal drug raw materials (HDRM), which are widely used in the preparation of many herbal drugs. Understanding of the microbial contamination status of HDRM is one of the important steps to ensure the safety and efficacy of herbal drugs. Materials and Methods: Eighteen samples of six herbal drug raw materials (HDRM) viz., Acorus calamus Linn., Cassia angustifolia Vahl., Centella asiatica (Linn.) Urban, Myristica fragrans Houtt.,Tinospora cardifolia (Wild) Miers and Withania somnifera (Linn.) Dunal, were screened for fungal contamination, by employing serial dilution method. All the isolates of Aspergillus flavus were screened for their ability to produce aflatoxin B1 (AB1) and highly contaminated samples were subjected to AB1 estimation by using Thin Layer Chromatography (TLC), spectrophotometric method and occurrence of Aflatoxin B1 was confirmed by Liquid Chromatography-Mass Spectrometry analysis (LCMS). Results: A total of 302 isolates of 42 fungal species belonging to 17 genera were found in association with test the samples. More than 61% of A. flavus isolates tested positive for production of AB1 and highest yield recorded was 5008.20 ppb from the isolates of T. cordifolia. Amongthesix highly contaminated samples three samples tested positive for AB1. Highest AB1 was recorded from T. cordifolia (104.19 µg/kg), followed by A. calamus (13.73 µg/kg) and M. fragrans (12.02 µg/kg). Conclusion: Assessment of fungal and mycotoxin contamination should be a part of the quality check while selecting HDRM for manufacture of herbal products. Safeprocessing and storage practices are necessary.
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Steshenko, Y. V., O. V. Mazulin, T. V. Oproshanska, and G. P. Smoylovska. "The microscopical investigation of diagnostic diseases of Thymus х Citriodorus var. «Silver Queen» herbs." Farmatsevtychnyi zhurnal, no. 5 (October 29, 2019): 92–98. http://dx.doi.org/10.32352/0367-3057.5.19.10.

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The actual problem of modern pharmacy is the study of promising essential oil plant species with pronounced antimicrobial and anti-inflamattory activity for their further introduction in medical practice. Species of one of the most famous Thymus L. genus are characterized by a great diversity and distribution in the world flora. The genus has about 400 species, of which up to 50 are identified in the modern flora of Ukraine. They are widespread in countries of Europe, Minor Asia, Middle Asia, North Africa, and the Mediterranean basin. Phytochemical studies the species of the Thymus L. genus were established the accumulation of various biologically active substances: essential oils, flavonoids, hydroxycinnamic acids, polysaccharides, tannins, fatty oils, vitamins, triterpene saponins, amino acids, bitterness, gums, inorganic elements. Essential oils and herbal extracts are part of phytopreparations with pronounced antimicrobial, anti-inflammatory and antioxidant activity. Ornamental varieties of this species are successfully cultivated in Western Europe and Ukraine: «Silver Queen», «Doone Vally», «Golden Duarf», «Bertram Anderson». Lemon thyme (Thymus x citriodorus Pers. Schreb. var. «Silver Queen») is promising for cultivation and introduction into medical practice. The plant has the necessary raw materials and a promising composition of biologically active compounds. The aim of the work is to install the characteristic microscopic diagnostic features of lemon thyme herb (Thymus x citriodorus Pers. Schreb. var. «Silver Queen»), harvested in Ukraine. We carried out a morphological, anatomical and microscopic study of fresh and dried herbal raw materials. The results of the research were obtained with a «Micromed XS-3320» microscope with a digital camera (5 mpix) in combination with a computer and «Biolam» with an FN-6 photo nozzle for direct and reflected light. When conducting morphological, anatomical and microscopic study of herbal raw materials of lemon thyme, common and distinctive features were established. Morphological, anatomical and microscopic studies of lemon thyme herbal raw materials were conducted and common and distinctive features were established. The established distinctive diagnostic features of lemon thyme can be used to identify herbal raw materials and are included in the draft article of the state pharmacopoeia of Ukraine «Herba Thymus x citriodorus Pers. Schreb. var. «Silver Queen».
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Mrozek-Szetela, Aneta, Piotr Rejda, and Katarzyna Wińska. "A Review of Hygienization Methods of Herbal Raw Materials." Applied Sciences 10, no. 22 (November 21, 2020): 8268. http://dx.doi.org/10.3390/app10228268.

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This article reviews various decontamination methods of herbal raw materials in Poland. These are the physical and chemical treatments of plant raw materials that remove mineral and microbiological impurities to ensure food safety. There is increasing use of herbal raw materials, and it is important to understand various methods that can be used for hygienization. Techniques used ensure the removal of mechanical impurities and elimination of microorganisms in a plant material. Depending on the method of choice, certain microorganisms are removed to a varying degree, and at the same time, there is a partial loss of the health-promoting properties of the plants subjected to the hygienization. Therefore, there is need to decide on optimal methods for hygienization of herbs that both reduce microbial contamination to the maximum extent and minimize the decrease in valuable ingredients contained in the herbs. Ozonization of plant raw materials is an effective method of removing microbiological contamination from most herbs. A good solution is also to use hybrid methods. In our literature review, ozone is very often mentioned as an effective disinfectant for herbs and spices. However, there is no information about the effect of ozone use on the substances contained in herbs and spices.
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Wojtowicz, Elżbieta, Aldona Krupska, and Renata Zawirska-Wojtasiak. "Antioxidant activity and free radicals of roasted herbal materials." Herba Polonica 63, no. 2 (June 1, 2017): 34–41. http://dx.doi.org/10.1515/hepo-2017-0011.

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Summary Introduction: Novel raw materials are being constantly searched for chicory coffee, which thanks to their specific composition can influence human health, thus promoting properties and of course the attractive aroma. Prior to their addition herbs – sea buckthorn (Hippophaë rhamnoides L.), rowanberry (Sorbus aucuparia L.), lovage roots (Levisticum officinale Koch) and dandelion (Taraxacum officinale coll.) – are roasted, which may change their antioxidant properties and generate free radicals with pro-oxidative properties. Objective: The characteristic of antioxidant activity of roasted herbal raw materials (sea buckthorn fruits, rowanberry, lovage roots and dandelion roots) for the production of chicory coffee and to determine the level of free radicals formed under the influence of roasting. Methods: Total phenolic contents were determined before and after the roasting process using the Folin-Ciocalteu phenol reagent and antioxidant activity by ABTS and DPPH assays. Free radicals were examined using electron paramagnetic resonance (EPR) spectroscopy. Results: The roasted materials were good sources of bioactive compounds, estimated at the total phenolic levels from 23.9 to 38.8 mg GAE/g. The highest antioxidant activity by ABTS and DPPH at 109.6 and 71.0 mg Tx/g was determined in roasted sea buckthorn. Free radicals were present in both the raw and roasted herbal materials. Roasted materials were characterised by markedly higher free radical concentrations when compared with the corresponding samples. The lowest free radical concentrations were recorded for roasted sea buckthorn fruits (0.031 × 1015 spin/g). Conclusion: Despite a high content of compounds with potent antioxidant activity, free radicals were present in novel roasted herbal materials. The formation of both antioxidant molecules and free radicals during the roasting process demonstrates that the two processes were not inversely related.
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Kim, Sul-Ki, and Chang-Gue Son. "Analysis of patents targeting antimetastatic effect using herbal materials." Integrative Medicine Research 9, no. 4 (December 2020): 100427. http://dx.doi.org/10.1016/j.imr.2020.100427.

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Roy, Dhritiman, Arindam Chakraborty, Payel Mukherjee, Balaram Ghosh, and Manas Chakraborty. "Recent Advances in Herbal Medicines – An Updated Review." Asian Journal of Pharmaceutical Research and Development 10, no. 1 (February 15, 2022): 45–48. http://dx.doi.org/10.22270/ajprd.v10i1.1089.

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Nowadays peoples throughout the world have been attracting towards the herbal medicines. Worldwide favour the traditional healthcare system, so day-by-day uses of herbal remedies to cure diseases is increase instead of alternative medicines. Herbal drugs have an ability to maintain health and to treat various diseases therefore herbal drugs have been used since very earlier days. To fulfil the public requirement many companies have been using herbal drug technology for converting botanical materials into medicines, where standardization, quality control, modern scientific techniques and traditional knowledge are very necessary. This review focuses on recent trends in Herbal drugs and main motto is to explain the therapeutic effectiveness of various herbal drugs, adverse drug reactions, drug interactions, standardization and stability testing of herbal medicines, pharmacovigilance and regulatory status of herbal medicines.
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Damanik, Wawan Septiawan, Gustina Siregar, Dewi Andriany, and Lila Bismala. "Peningkatan Kapasitas Produksi dan Pengembangan Kelembagaan pada Usaha Minuman Tradisional Kostfood." Aksiologiya: Jurnal Pengabdian Kepada Masyarakat 6, no. 3 (July 25, 2022): 370. http://dx.doi.org/10.30651/aks.v6i3.9209.

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Minuman herbal merupakan warisan budaya yang di ajarkan oleh orang tua terdahulu yang sangat bermanfaat untuk meningkatkan kekebalan tubuh. Hingga saat ini masih banyak masyarakat yang memilih mengkonsumsi minuman herbal dikarenakan bersumber dari bahan yang alami sehingga tidak menyebabkan efek samping dan reaksi berbehaya terhadap tubuh. Mitra pada perogram pengabdian masyarakat merupakan pengerajin minuman herbal hingga dikenal kota Kisaran Sumatera Utara. Mitra memproduksi minuman herbal yang berbahan utama jahe untuk di jual kepada masyarakat sekitar. Semakin hari, permintaan minuman herbal yang di produksi mitra semakin meningkat dan mitra merasa sulit untuk memenuhi permintan karena minimnya alat produksi dan masih dikerjakan secara manual. Dengan memberikan mesin-mesin produksi, permasalahan yang dihadapi mitra saat ini dapat teratasi. Produksi minuman herbal yang di awal hanya mampu memproduksi 20 kg/hari, kini dengan menggunakan mesin penggiling basah, mesin pengaduk otomatis, dan mesin penggiling kering produksi minuman herbal meningkat 90% yaitu sekitar 180 kg/hari
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Manani, Lata, Manan Raval, Chandni Chandarana, Kishori Gawas, and Parixit Prajapati. "Standardization, evaluation and quantification of herbal drugs by various analytical methods." International Journal of Ayurvedic Medicine 13, no. 3 (October 9, 2022): 613–24. http://dx.doi.org/10.47552/ijam.v13i3.2804.

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This review article encompasses the various evaluation parameters of standardization of different medicinal plants and its constituents. In today’s life, more and more people of the world are turning towards the use of natural or herbal products as these have very less or negligible side effects. As the use of herbal medicinal products is increasing day by day, the questions regarding their quality are also arising. This is due to lack of parameters for the standardization of these products. There is a need to set different parameters or methods that can help to standardize the herbal medicinal plant materials. Various methods like physical, chemical, biological is used for standardization and quality evaluation of herbal medicinal plants. These methods can act as a basic tool for the quality evaluation of herbal plant materials. Different parameters of standardization are the fundamental tool for evaluating and assuring the quality of the herbal plant material and its products. This review article includes the quantitative evaluation of more than 20 herbal drugs. The evaluation parameters such as TLC, HPLC, HPTLC, GC, LC-MS, UPLC, UHPLC, UPLC-MS, UHPLC-MS will help to maintain quality of different herbal medicinal drugs as well as its formulations. The set parameters can ultimately lead to the quality and efficacy of the herbal medicinal formulations. Analytical methods and standardization can ensure the quality and consistency of active ingredients in herbal medicinal formulations.
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Hadiati, S. W., H. Winarno, and S. Pramono. "Gamma irradiation as suitable preservation method on herbal medicine: a review." Food Research 5, no. 5 (August 31, 2021): 33–42. http://dx.doi.org/10.26656/fr.2017.5(5).494.

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The trend of consuming herbal medicines has been increasing over the past three decades. No less than 80% of the world's population has used herbal medicines as a treatment. One of the problems in herbal medicine is the high level of microbial contamination caused by raw materials and production processes. Various attempts have been made to overcome these problems, one of them is the gamma irradiation method. Although irradiation has been widely used for food sterilization, the use of irradiation for sterilization on herbal medicines is still debated. It is because irradiation may affect the composition of active compounds of herbal medicines. This review aimed to discuss the applications of gamma irradiation for herbal medicines by emphasizing the chemical constituent stabilities of herbal medicines.
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Karobari, Mohmed Isaqali, Abdul Habeeb Adil, Ali A. Assiry, Syed Nahid Basheer, Tahir Yusuf Noorani, Ajinkya M. Pawar, Anand Marya, Pietro Messina, and Giuseppe Alessandro Scardina. "Herbal Medications in Endodontics and Its Application—A Review of Literature." Materials 15, no. 9 (April 25, 2022): 3111. http://dx.doi.org/10.3390/ma15093111.

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Herbal products are gaining popularity in dental and medical practice nowadays due to their biocompatibility, higher antimicrobial activity, antioxidant and anti-inflammatory properties. Herbal medicine has experienced rapid growth in recent years due to its beneficial properties, ease of availability, and lack of side effects. As pathogenic bacteria become more resistant to antibiotics and chemotherapeutic agents, researchers are becoming more interested in alternative products and treatment choices for oral diseases. As a result, natural phytochemicals separated from plants and utilized in traditional medicine are suitable substitutes for synthetic chemicals. The aim of this review article is to list and understand several herbal alternatives that are currently accessible for use as efficient endodontic medicaments. The herbal products used in endodontics have several advantages, including safety, ease of use, increased storability, low cost, and a lack of microbial tolerance. However, preclinical and clinical testing and interactions with other materials and adverse effects are required for these herbal products.
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Karobari, Mohmed Isaqali, Abdul Habeeb Adil, Ali A. Assiry, Syed Nahid Basheer, Tahir Yusuf Noorani, Ajinkya M. Pawar, Anand Marya, Pietro Messina, and Giuseppe Alessandro Scardina. "Herbal Medications in Endodontics and Its Application—A Review of Literature." Materials 15, no. 9 (April 25, 2022): 3111. http://dx.doi.org/10.3390/ma15093111.

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Herbal products are gaining popularity in dental and medical practice nowadays due to their biocompatibility, higher antimicrobial activity, antioxidant and anti-inflammatory properties. Herbal medicine has experienced rapid growth in recent years due to its beneficial properties, ease of availability, and lack of side effects. As pathogenic bacteria become more resistant to antibiotics and chemotherapeutic agents, researchers are becoming more interested in alternative products and treatment choices for oral diseases. As a result, natural phytochemicals separated from plants and utilized in traditional medicine are suitable substitutes for synthetic chemicals. The aim of this review article is to list and understand several herbal alternatives that are currently accessible for use as efficient endodontic medicaments. The herbal products used in endodontics have several advantages, including safety, ease of use, increased storability, low cost, and a lack of microbial tolerance. However, preclinical and clinical testing and interactions with other materials and adverse effects are required for these herbal products.
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Aminova, Al'bina, Idris Yumaguzin, Niyaz Subhankulov, and Tatyana Sedykh. "Efficacy of a herbal drug in treating bovine mastitis." Agrarian Bulletin of the 209, no. 06 (July 15, 2021): 34–42. http://dx.doi.org/10.32417/1997-4868-2021-209-06-34-42.

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Abstract. Presently, mastitis is being addressed by biologically active agents of plant origin having a bactericidal, viricidal and immune-modulating effect. In this regard, the study of the Raido drug to treat different types of mastitis in lactating cows is of a certain scientific and practical importance. The aim of the study was to determine the efficacy of the Raido herbal drug against serous and catarrhal mastitis in cows during the lactation period. Research methods. Mastitis was detected according to clinical observations, with the results being confirmed by the express diagnosticum Mastidinum or a quick mastitis test. The blood morphological composition in terms of erythrocyte, leucocyte and haemoglobin content was analyzed on a haematological analyzer. Milk samples were examined bacteriologically for the pathogenic microflora. Results. Treating serous and catarrhal mastitis with the Raido herbal drug increased the level of erythrocytes and haemoglobin in recovering cows, reduced their leucocyte content in the peripheral blood, and somatic cells in milk more than doubled. There were no clinical signs of the disease on the fifth day when serving serous mastitis with 5 or 7 ml of the herbal drug intercisternally. Treating catarrhal mastitis with 10 and 12 ml of the drug using the same administration method produced a similar effect on the sixth day. Thus, the optimal dose for daily interstitial administration of serous mastitis was 5 ml and 10 ml for catarrhal mastitis. A comparison of the therapeutic effects of the phytomedicines Raido and Riposol revealed higher efficacy of the daily Raido use in these dosages. Scientific novelty. For the first time, the optimal dosage of the Raido herbal drug for intercisternal administration to cows with serous and catarrhal mastitis was determined; the therapeutic effect of the Raido herbal remedy was detected; a comparative assessment of the Raido and Riposol herbal remedies' effect in the treatment of serous and catarrhal mastitis was made.
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P, Santhosh Kumar, Pushkar Ketkar, Shraddha Nayak, and Subarna Roy. "Application of DNA fingerprinting tools for authentication of ayurvedic herbal medicines- A review." Journal of Scientific and Innovative Research 3, no. 6 (December 25, 2014): 606–12. http://dx.doi.org/10.31254/jsir.2014.3612.

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Ayurvedic herbal medicines played a pivotal role in maintaining health and treating the disease worldwide since ancient times. Due to renewed interest and popularity the global market strategy is worth about $ 60 billion annually. As commercialization and increased demand safety, quality and assurance of Ayurvedic herbal medicines is biggest lacuna. The adulteration of herbal materials usually occurs as a result of materials not having readily distinguishable morphological features, materials sharing similar common names and the substitution of economically valuable materials with inexpensive herbs. Proper authentication process is necessary to prevent the adulteration. Since the standardization of botanical preparations most of the regulatory authorities suggest macroscopic, microscopic and chemical evaluation like TLC, HPTLC and HPLC. However, these methods have limitations because the composition and relative amount of chemicals in a particular species of plant varies with growing conditions-harvesting period, post harvesting period and storage conditions. The present review mainly focuses on authentication of Ayurvedic herbal medicines by DNA based fingerprinting methods to prevent intentional and in-advertant adulteration or substitution of targeted Ayurvedic medicinal herbs.
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Nakai, Kenichiro, Takeshi Maeda, Guang Hong, Tadafumi Kurogi, and Joji Okazaki. "Effects of herbal medicine components on the physical properties of trial denture adhesives." Dental Journal (Majalah Kedokteran Gigi) 50, no. 4 (December 30, 2017): 171. http://dx.doi.org/10.20473/j.djmkg.v50.i4.p171-177.

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Background: Denture adhesive is widely used in elderly people who wear complete dentures. Chinese herbal medicine has long been used for the treatment of oral disease. The addition of herbal medicine to denture adhesive might be used to develop an adhesive which is effective for xerostomia patients. Purpose: The purpose of this study was to evaluate physical properties and cytototoxicity of herbal medicine components in denture adhesive. Methods: This study used a combination of 35wt% PVM-MA, 20wt% CMC, 40wt% white petrolatum and 5wt% liquid paraffin as base materials. Three kinds of herbal medicine components: Maimendong (Ophiopogon), Fuling (Hoelen) and Dongkuizi (Cluster mallow seed) were added to base materials of 1wt%, 5wt% and 10wt%. The initial viscosity was measured using a controlled-stress rheometer (AR-G2). The adhesive strength was quantified according to ISO-10873 recommended procedures. All data was analyzed independently by one-way Anova combined with a Turkey’s multiple comparison test at a 5% level of significance. Results: Significant differences were observed between materials in initial viscosity (p < 0.05). Specifically, samples containing 5wt% and 10wt% of Maimendong (Ophiopogon) showed higher values compared with the control samples. The larger the amounts of herbal medicine components, the greater the changes in the adhesive strength of denture adhesives over time. The denture adhesives containing herbal medicine components do not have a cytotoxic effect and are safe for use in actual clinical practice. Conclusion: The study showed that the addition of herbal medicine components does not affect physical properties (i.e. initial viscosity and adhesive strength) of denture adhesive and cytotoxicity in fibroblast cells.
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Singh, Priyanka, Bhawana Srivastava, Ashok Kumar, and N. K. Dubey. "Fungal Contamination of Raw Materials of Some Herbal Drugs and Recommendation of Cinnamomum camphora Oil as Herbal Fungitoxicant." Microbial Ecology 56, no. 3 (March 6, 2008): 555–60. http://dx.doi.org/10.1007/s00248-008-9375-x.

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Dev, Asish, and Dhanashree Santosh Kadam. "Perspective on Traditional Herbal Medicine – Ashwagandha." Journal of Advances in Bio- pharmaceutics and Pharmacovigilance 4, no. 1 (May 17, 2022): 9–22. http://dx.doi.org/10.46610/jabp.2022.v04i01.002.

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Herbal medicines comprise of herbs, its materials, preparations, and finished products, that contains main constituents which are parts of plants, plant materials, their combinations. In Ayurveda's medical armamentarium, Ashwagandha remains renowned for improving health and well-being, and has proved to be beneficial in the treatment of many ailments. Ashwagandha (Withania somnifera) [L. Dunal, Family: Solanaceae] is one of the leading and appreciated therapeutic plant of the Indian Ayurvedic medicine system. Ashwagandha is also called as poisonous gooseberry, winter cherry, and Indian ginseng. Inclination to develop new products with Ashwagandha bioactive molecules continues. Ashwagandha is a potential medicinal plant that can produce international business in India. Scientific studies on this plant need to be expanded with more immediate comparisons in order to effectively limit patent technology based on this plant and to utilize a few of its therapeutic uses at the highest level.
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Baruah*, Prantik Sharma, and Borthakur S. K. "Formulation of an herbal mosquito repellent." Annals of Plant Sciences 5, no. 12 (December 20, 2016): 1463. http://dx.doi.org/10.21746/aps.2016.12.002.

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The present paper deals with formulation of a mosquito repellent product prepared using four plant materials viz, Homalomena aromatica, Ocimum basilicum, Ageratum conyzoides and Litsea glutinosa based on traditional knowledge in prevalent among the ethnic groups of Assam.
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Sasmita Reza, Jihan, and Maysarah Binti Bakri. "Upaya Pemberdayaan Apotek Hidup Dan Pentingnya Tanaman Obat Dalam Menjaga Imunitas Tubuh Selama Pandemi Covid-19." Jurnal Riset dan Pengabdian Masyarakat 2, no. 1 (January 18, 2022): 57–66. http://dx.doi.org/10.22373/jrpm.v2i1.1157.

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The Covid-19 pandemic delays learning activities on campus, especially in the process of practicum, student community service (KPM), and completing final assignments. Not only students, the pandemic also has an impact on the society. This condition requires the society to be healthy for doing daily activities. One way to do it is by consuming healthy and natural food such as vegetables or herbals. The objectives of this study were (1) to identify the types of to improve the health status of society, (2) to find out the way of using herbals in the program and the benefit of it as raw materials for herbal medicine as an alternative of chemical drugs. The KPM student initiates to make a living pharmacy to improve the body’s immune system. The students performs Covid-19 prevention socialization and train the village community of Doy, in the cultivation of herbs to maintain the immunity. The expected result of such activities is increasing society’s interest in growing a living pharmacy plant in their yard, increasing society knowledge in optimizing their garden for the cultivation of living pharmacies, and increasing public knowledge regarding the advantages of each herbal plant
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Chebyshev, N. V., A. V. Strelyaeva, D. I. Lezhava, A. N. Luferov, N. V. Bobkova, N. V. Kartashova, and R. M. Kuznetsov. "Investigation of Walnut Herbal Drug Raw Material." Drug development & registration 8, no. 4 (November 26, 2019): 38–46. http://dx.doi.org/10.33380/2305-2066-2019-8-4-38-46.

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Introduction. Walnut (Juglans regia L.) is a medicinal plant containing a large number of biologically active substances. A number of authors propose to use walnut leaves as medicinal raw materials, in which juglone, flavonoids, tannins, ascorbic acid and other substances are identified. Currently, a standardization technique for this type of raw material has been developed and proposed. However, the medicinal plant walnut can be a source of other types of raw materials, such as milky-waxed walnuts, walnut bark, and walnut partitions. These types of medicinal raw materials contain a large number of biologically active substances and have a great potential for pharmacological activity. Therefore, the study with the subsequent standardization of medicinal plant material of walnut fruits in the stage of milk-wax ripeness and walnut bark is relevant.Aim. The aim of the study is to study the external signs, microscopy of raw walnut bark and walnut fruit in the stage of milky-wax ripeness and chemical composition of alcohol extract from these types of raw materials.Materials and methods. Chromato-mass spectrometry and TLC were used in the work.Results and discussion. When describing external signs and microscopy, diagnostic signs of both whole and crushed raw materials, and powder of walnut bark, and fruits of walnut in the stage of milky-wax ripeness were revealed. Alcohol extract obtained from medicinal plant raw materials walnut bark is a clear brown liquid. Alcohol extract obtained from medicinal plant raw materials of walnut fruit at the stage of milky-wax ripeness is a transparent, green-brown liquid with a fragrant odor.Conclusion. Gallic acid was identified by TLC in walnut bark. Chromato-mass spectrometry in alcohol extraction from the fruit of walnut in the stage of milky-wax maturity was able to identify 17 compounds belonging to different classes of biologically active substances. Sugars, flavonoids, coumarin phenolic compounds, organic acids were identified. In alcoholic extraction from the bark of a walnut, marker compounds have been determined, the combination of which makes it possible to quickly identify this type of raw material using chromatography-mass spectrometry.
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Utami, N., I. S. Bidara, J. I. Royani, R. Reninta, I. Dwimahyani, and D. Mulyono. "Increasing secondary metabolites production of Phyllanthus sp to support development of herbal medicine industry." IOP Conference Series: Earth and Environmental Science 1114, no. 1 (December 1, 2022): 012082. http://dx.doi.org/10.1088/1755-1315/1114/1/012082.

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Abstract This study aim to improve the quality of Phyllanthus sp production by increasing the content of secondary metabolites as a bioactive compound. Phyllanthus sp contains various secondary metabolites that enhance immunity and treat diabetes, hypertension, antioxidants, anti-cancer, kidney disorders, and other illnesses. Since the Covid-19 pandemic, Phyllanthus sp widely used as a raw material for making herbal medicines. The trade value of Indonesian herbal medicines is estimated to increase in 2022, and the price will reach around the US $ 910 million, so it has very bright business prospects. These relatively limited phytopharmaceutical products constrain the supply of high-quality raw materials under the requirements of the herb medicine industry. Therefore, conducting a depth assessment related to efforts to improve the quality of Phyllanthus sp production by increasing the content of secondary metabolites is necessary. The efforts to enhance the quality of Phyllanthus sp as a source of herbal medicine raw materials can be made through plant breeding such as genetic mutations and in combination with the environmental arrangements of soil water content and solar radiation intensity. The efforts to increase the quality of herbal medicine raw materials are critical to support the development of the herbal medicine industry.
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Ming, Li, Wei Xia, Bo Dong, Jun Hua Mao, Xin Wen Zhoug, and Jia Rong Pan. "Study on the Preparation and Adsorption Properties of Activated Carbon Obtained from Chinese Herbal Medicine Residue." Advanced Materials Research 904 (March 2014): 200–204. http://dx.doi.org/10.4028/www.scientific.net/amr.904.200.

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In this paper, we use residue of ten different Chinese herbal medicine as raw material and ZnCl2, KOH,K2CO3 as activator, using chemical activation method to prepare activated carbon, and we do performance testing on the activated carbon. The experimental process includes the preparation and properties testing of activated carbon, as well as testing the content of leading components of lignin in these Chinese herbal medicine raw materials and their calorific values. We've studied the relationship between leading components of these raw materials and out put and properties of the activated carbon. As a result, we got that using KOH and K2CO3 as activator to prepare activated carbon is a good choose for residue of Chinese herbal medicine belonging to rootstock which contains high content of lignin.And ZnCl2 for residue of Chinese herbal medicine belonging to cane.
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Toktonalieva, N., and I. Toktonaliev. "Studying the Attitude of Pharmaceutical Workers of the Kyrgyz Republic to Medicinal Products of Plant Origin." Bulletin of Science and Practice 6, no. 8 (August 15, 2020): 130–34. http://dx.doi.org/10.33619/2414-2948/57/10.

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Herbal medicines currently widely used for the treatment and prevention of various diseases. Their share now is about 30% among all medicines and will only increase in the future. Therefore, every year the range of herbal remedies is expanding in pharmacies. At the same time, concerns about safety regarding the widespread use of herbal medicines among healthcare workers have increased, as the Kyrgyz population still believes that herbal medicines are safe and have a mild effect on the body. Our study aimed at assessing the knowledge, attitudes and practices of pharmacists in the field of herbal medicines. This article presents the results of a questionnaire survey conducted among pharmaceutical workers of the Kyrgyz Republic. The research materials used specially designed questionnaires, including the demographic characteristics of the participants, their knowledge, perception, attitude to the use of herbal remedies, and included issues of the effectiveness and safety of herbal medicines. In the course of the study, pharmacoepidemiological, sociological research methods and an expert assessment method used. The results of the study showed that the majority of pharmacists consider herbal medicine effective and safe, and noted that providing reliable information when dispensing herbal preparations is their professional responsibility.
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Хохлова, К. О. "Scientific-methodological approach for standardization of herbal raw materials and herbal preparations using high-performance thin-layer chromatography procedure." Farmatsevtychnyi zhurnal, no. 4 (August 26, 2021): 76–89. http://dx.doi.org/10.32352/0367-3057.4.21.07.

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The high-performance thin-layer chromatography (HPTLC) is widely used for quality control of herbal raw materials (HRM). The purpose of this work were to define the problematic issues of quality control of herbal drugs in Ukraine and to develop a systematic scientific and methodological approach for the standardization of HRM and herbal drugs using the modern analytical technique of HPTLC: to optimize the existing and develop new methods of identification and determination of adulterations, and to develop alternative methods of quantitative determination, as well as studying of the stability. As a result of a critical evaluation of existing approaches for the standardization of HRM and herbal drugs of Ukraine’s flora, numerous problematic issues were identified, including the existence of a limited number of national monographs / national parts of monographs on the HRM of the Ukraine’s flora, which were not previously standardized by other pharmacopeias; non-consideration of Ukraine’s flora species (non-pharmacopoeial) in monographs on closely related species that introduced in the State Pharmacopoeia of Ukraine; lack of specificity of combinations of physical and chemical methods used for quality control; lack of specificity and reproducibility, the labor intensity of methods; necessity of usage of toxic solvents and precursors; use of different groups of markers and methods for the HRM and its finished product or HRM and its closely related species, etc. The proposed systematic scientific and methodological approach includes: a preliminary collection of information about the object of study, markers/groups of bioactive substances, approaches to its standardization; theoretical evaluation of existing techniques of quality control in monographs on HRM and experimental approbation using samples of domestic plants, determination of the need for optimization of existed methods by the parallel development of specific, reproducible and documented methods for identification, adulterations’ detection, quantification, and bio-detection (if necessary) by HPTLC method. The approach is illustrated with examples. The proposed approach can be used for comprehensive HPTLC analysis of domestic HRM and herbal drugs for research, prevention of adulteration, standardization of initial HRM and its finished product, pharmaceutical development, and stability studies.
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Raudonis, Raimondas, Lina Bumblauskiene, Valdas Jakstas, Audrius Pukalskas, and Valdimaras Janulis. "Optimization and validation of post-column assay for screening of radical scavengers in herbal raw materials and herbal preparations." Journal of Chromatography A 1217, no. 49 (December 2010): 7690–98. http://dx.doi.org/10.1016/j.chroma.2010.10.017.

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Sugiarti, Lilis, Dian Arsanti Palupi, and Indah Febriana. "Effect of Ethanol Extract from Herbal Consortium for Pytirosporum ovale Inhibition." JURNAL SAINS NATURAL 12, no. 4 (November 12, 2022): 184. http://dx.doi.org/10.31938/jsn.v12i4.444.

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Dandruff is a skin disease caused by the fungus Pytirosporum ovale. The use of chemical compounds for dandruff is very limited and can cause side effects, such as toxicity to the eyes and hair becoming too dry. The consortium of herbal plants was hope had greater inhibitory activity than the single plants. The purpose of this study was to determine the antifungal effectiveness of a consortium of herbs (soursop leaves, basil leaves, bay leaves and green betel leaves) in a 1:1:1:1 ratio against Pytirosporum ovale. Extraction method using maceration method and 70% ethanol solvent. The extract of the herbal consortium was made in series with concentrations of 10, 25, 40, 55 and 70%, a negative control and a positive control by disc diffusion method. Data analysis using Post Hoc LSD test, correlation, and linear regression. The results showed that all concentrations of extract of the herbal consortium could inhibit the activity of the fungus Pytirosporum ovale. The minimum inhibitory concentration was at a concentration of 10% with a diameter of 7.33 mm while the optimum inhibitory at a concentration of 70% with a diameter of 15.55 mm. The inhibition zone diameter in positive control of 24.66 mm. The results of the correlation test show a very strong and unidirectional relationship. The results of the linear regression test obtained the value of y=0.138x+5.889. The diameter of the fungal inhibition zone was influenced by the extract concentration of 99.99% (r2=0.9999), the remaining 0.01% was influenced by other factors such as temperature, radiation, light, humidity, pH and others. The ethanol extract of the herbal consortium was not effective in inhibiting the growth of the fungus Pytirosporum ovale when compared to positive control.Keywords: Herbal consortium; Ethanol extract; Antifungal; MIC; Pytirosporum ovaleABSTRAKEfektivitas Ekstrak Etanol Konsorsium Herbal terhadap Pytirosporum ovaleKetombe merupakan penyakit kulit yang disebabkan adanya jamur Pytirosporum ovale. Konsorsium herbal diharapkan mempunyai potensi antijamur yang lebih besar dari pada herbal tunggalnya. Penelitian dengan menggunakan daun sirsak, daun kemangi, daun salam dan daun sirih hijau, bertujuan untuk mengetahui efektivitas ekstrak konsorsium herbal perbandingan 1:1:1:1 terhadap Pytirosporum ovale. Ekstraksi senyawa aktif menggunakan metode maserasi dan pelarut etanol 70%. Ekstrak konsorsium herbal dibuat seri konsentrasi 10, 25, 40, 55 dan 70%; kontrol negatif dan kontrol positif dengan metode difusi cakram. Data dianalisis menggunakan uji Post Hoc LSD, korelasi dan regresi linier. Hasil penelitian menunjukkan semua konsentrasi ekstrak konsorsium herbal berpotensi menghambat aktivitas jamur Pytirosporum ovale. Daerah hambat terkecil terdapat pada konsentrasi ekstrak 10% dengan diameter daerah hambat sebesar 7,33 mm sedangkan daerah hambat terbesar terjadi pada konsentrasi ekstrak 70% dengan diameter daerah hambat sebesar 15,55 mm. Diameter daerah hambat pada kontrol positif sebesar 24,66 mm. Hasil uji korelasi menunjukkan ada hubungan yang sangat erat antara konsentrasi ekstrak dengan diameter daerah hambat. Hasil uji regresi linier diperoleh nilai y=0,138x+5,889. Diameter daerah hambat jamur terpengaruhi oleh konsentrasi ekstrak sebesar 99,99% (r2=0,9999), sisanya sebesar 0,01% oleh faktor lingkungan, Ekstrak etanol konsorsium herbal belum efektif dalam menghambat pertumbuhan jamur Pytirosporum ovale bila dibandingkan dengan kontrol positifnya.Kata kunci: Konsorsium herbal, Ekstrak etanol, Antijamur, KHM, Pytirosporum ovale
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Ramirez, L. I., O. N. Kanwugu, and M. N. Ivantsova. "Impact of herbal supplements nowadays: an overview." Chimica Techno Acta 9 (April 22, 2022): 202292S4. http://dx.doi.org/10.15826/chimtech.2022.9.2.s4.

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At present, people around the world are looking for more natural alternatives for treating all kinds of health conditions as well as improving the general wellbeing. As such, the consumption of herbal supplements has increased globally, generating billions in revenue. The use of these herbal products is firmly rooted in the traditional use of medicinal plants for disease prevention and treatment, practiced in several cultures. Although herbal products are recognized by the WHO as an essential component of the healthcare system, there have been increasing concerns regarding their quality and safety. Generally, herbal products are not strictly regulated as they are largely categorized under dietary supplements, thus escaping the rigorous scrutiny meted out to pharmaceuticals. Notwithstanding that many consumers generally perceive herbal products as benign and inherently safe, several reports have shown that herbal products can induce mild to acute adverse effects of clinical significance. Moreover, some herbal products on the market have been reported to be contaminated with microorganisms, environmental toxins, and adulterants. Furthermore, evidence regarding the efficacy of herbal supplements is extremely discrepant.
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Dziubanek, Grzegorz, Dawid Konwant, Danuta Rogala, and Joanna Domagalska. "Cadmium in herbal weight loss products as a health risk factor for consumers." Postępy Higieny i Medycyny Doświadczalnej 76, no. 1 (January 1, 2022): 165–73. http://dx.doi.org/10.2478/ahem-2022-0021.

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Abstract Introduction Herbal weight loss remedies are produced from various plant species which could accumulate heavy metals from the environment. The consumption of contaminated herbal preparations could be a source of consumer exposure to toxic metals. The aim of the study was to evaluate the content of cadmium in selected herbal weight loss products available on the Polish market, to determine exposure of consumers to the heavy metal included in herbal infusions prepared from the studied products and the related health risk. Materials and Methods The study included 29 herbal weight loss products available on the Polish market. The content of cadmium in the analyzed dried herbs and herbal infusions was analyzed. Based on the obtained results, the exposure of consumers to cadmium and the related health risks were estimated. Results Cadmium concentration in dried herbs did not exceed the maximum allowable concentration. Conclusions The exposure of consumers of the most contaminated herbal infusions to cadmium could be equal to half of the reference dose, which is an acceptable exposure threshold.
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46

Pal, Rashmi S., Nikita Saraswat, Pranay Wal, Ankita Wal, and Yogendra Pal. "Preparation & Assessment of Poly-Herbal Anti-Dandruff Formulation." Open Dermatology Journal 14, no. 1 (July 6, 2020): 22–27. http://dx.doi.org/10.2174/1874372202014010022.

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Background: Dandruff is a major problem of hair, which cannot be fully cured with the aid of chemicals. An attempt has been made to prepare a poly-herbal anti-dandruff hair care formulation and it is standardized to ensure its stability and quality aspects. Objective: The present work is oriented at the synthesis of herbal anti-dandruff hair formulation and the estimation of its various aspects for its valuability. Materials and Methods: The herbal preparation was prepared in the laboratory, on the basis of decided proportion, with the help of all the herbal contents. The pack was gauged for its various parameters. Results: The results were concluded to be sufficiently ample for the assessment of herbal formulation. The findings of different aspects vindicated the worth of the formulation. Conclusion: Herbal hair formulation has been formulated and assessed using the various aspects. It serves as a good alternate, devoid of any side effects. The results can be unified while evolving the pharmacopoeial standards.
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Livne, Shiri, Sapir Simantov, Arkadi Rahmanov, Uziel Jeffet, and Nir Sterer. "Hydroxyethyl Cellulose Promotes the Mucin Retention of Herbal Extracts Active against Streptococcus mutans." Materials 15, no. 13 (July 1, 2022): 4652. http://dx.doi.org/10.3390/ma15134652.

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Streptococcus mutans is considered a major cariogenic bacterium. Most anti-cariogenic dentifrices are limited by a short exposure time. The aim of the present study was to test the hypothesis that adding a mucoadhesive agent to the formulation may increase its bioavailability and efficacy. We tested the effect of adding hydroxyethyl cellulose (HEC) to an herbal extract solution containing lavender, echinacea, sage, and mastic gum, which have been previously shown to be effective against Streptococcus mutans. Mucin-coated wells were treated with four test solutions: saline, herbal extracts, herbal extracts with HEC, and chlorhexidine. The wells were incubated with Streptococcus mutans and studied for biofilm formation (Crystal violet assay), acid production (lactate assay), acid tolerance (ATPase assay), and exopolysaccharide (EPS) production using fluorescent microscopy. The results showed that the addition of HEC to the herbal extract solution caused a significant reduction in Streptococcus mutans biofilm formation, lactic acid production, and EPS quantity (p < 0.001). These results suggest that HEC may be a beneficial added excipient to herbal extracts in an anti-cariogenic formulation.
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Ngari, FW, RN Wanjau, EN Njagi, and NK Gikonyo. "Herbal Materials Used in Management of Oral Conditions in Nairobi, Kenya." Journal of Oral Health and Community Dentistry 8, no. 1 (January 2014): 36–42. http://dx.doi.org/10.5005/johcd-8-1-36.

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ABSTRACT Aim This study was carried out to document the medicinal plants used in management of oral health and diseases by traditional medical practitioners in Nairobi County, Kenya. Methods An ethnomedicinal survey was conducted using a standard questionnaire and informal discussion to collect information from traditional medical practitioners, traders and vendors of medicinal plants used in oral care practice. Results This study identified 35 species from 24 families, commonly used by the traditional medical practitioners in Nairobi to manage oral health and diseases in Nairobi County. Conclusion There are various plants that are used by traditional medical practitioners to manage oral diseases either singly or in combination.
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Larina, Galina V., and Angelina D. Makaryuk. "Biologically active components in herbal medicinal raw materials of Gorny Altai." Vestnik Тomskogo gosudarstvennogo universiteta. Khimiya, no. 21 (March 1, 2021): 18–31. http://dx.doi.org/10.17223/24135542/21/2.

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50

Zhogova, A. A., and K. I. Eller. "THE METODOLOGICAL APPROACH TO THE IRIDOID ANALYSIS IN HERBAL RAW MATERIALS." Reviews on Clinical Pharmacology and Drug Therapy 10, no. 2 (June 15, 2012): 48–49. http://dx.doi.org/10.17816/rcf10248-49.

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