Journal articles on the topic 'Hepatocyte nuclear factor'
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Eeckhoute, J. "Hepatocyte Nuclear Factor 4 enhances the Hepatocyte Nuclear Factor 1 -mediated activation of transcription." Nucleic Acids Research 32, no. 8 (April 28, 2004): 2586–93. http://dx.doi.org/10.1093/nar/gkh581.
Full textSund, Newman J., Siew-Lan Ang, Sara Dutton Sackett, Wei Shen, Nathalie Daigle, Mark A. Magnuson, and Klaus H. Kaestner. "Hepatocyte Nuclear Factor 3β (Foxa2) Is Dispensable for Maintaining the Differentiated State of the Adult Hepatocyte." Molecular and Cellular Biology 20, no. 14 (July 15, 2000): 5175–83. http://dx.doi.org/10.1128/mcb.20.14.5175-5183.2000.
Full textULVILA, Johanna, Satu ARPIAINEN, Olavi PELKONEN, Kaoru AIDA, Tatsuya SUEYOSHI, Masahiko NEGISHI, and Jukka HAKKOLA. "Regulation of Cyp2a5 transcription in mouse primary hepatocytes: roles of hepatocyte nuclear factor 4 and nuclear factor I." Biochemical Journal 381, no. 3 (July 27, 2004): 887–94. http://dx.doi.org/10.1042/bj20040387.
Full textWang, Zhongyan, and Peter A. Burke. "Hepatocyte nuclear factor-4α interacts with other hepatocyte nuclear factors in regulating transthyretin gene expression." FEBS Journal 277, no. 19 (August 23, 2010): 4066–75. http://dx.doi.org/10.1111/j.1742-4658.2010.07802.x.
Full textGardner-Stephen, Dione A., and Peter I. Mackenzie. "Hepatocyte nuclear factor1 transcription factors are essential for the UDP-glucuronosyltransferase 1A9 promoter response to hepatocyte nuclear factor 4α." Pharmacogenetics and Genomics 17, no. 1 (January 2007): 25–36. http://dx.doi.org/10.1097/fpc.0b013e32801112b5.
Full textKhurana, Satish, Amit K. Jaiswal, and Asok Mukhopadhyay. "Hepatocyte Nuclear Factor-4α Induces Transdifferentiation of Hematopoietic Cells into Hepatocytes." Journal of Biological Chemistry 285, no. 7 (December 16, 2009): 4725–31. http://dx.doi.org/10.1074/jbc.m109.058198.
Full textTian, J. M., and U. Schibler. "Tissue-specific expression of the gene encoding hepatocyte nuclear factor 1 may involve hepatocyte nuclear factor 4." Genes & Development 5, no. 12a (December 1, 1991): 2225–34. http://dx.doi.org/10.1101/gad.5.12a.2225.
Full textAboudehen, Karam, Min Soo Kim, Matthew Mitsche, Kristina Garland, Norma Anderson, Lama Noureddine, Marco Pontoglio, et al. "Transcription Factor Hepatocyte Nuclear Factor–1βRegulates Renal Cholesterol Metabolism." Journal of the American Society of Nephrology 27, no. 8 (December 28, 2015): 2408–21. http://dx.doi.org/10.1681/asn.2015060607.
Full textFreedman, A. R., R. J. Sharma, G. J. Nabel, S. G. Emerson, and G. E. Griffin. "Cellular distribution of nuclear factor κB binding activity in rat liver." Biochemical Journal 287, no. 2 (October 15, 1992): 645–49. http://dx.doi.org/10.1042/bj2870645.
Full textTang, Hong, and Alan McLachlan. "Avian and Mammalian Hepadnaviruses Have Distinct Transcription Factor Requirements for Viral Replication." Journal of Virology 76, no. 15 (August 1, 2002): 7468–72. http://dx.doi.org/10.1128/jvi.76.15.7468-7472.2002.
Full textPierreux, C. E., J. Stafford, D. Demonte, D. K. Scott, J. Vandenhaute, R. M. O'Brien, D. K. Granner, G. G. Rousseau, and F. P. Lemaigre. "Antiglucocorticoid activity of hepatocyte nuclear factor-6." Proceedings of the National Academy of Sciences 96, no. 16 (August 3, 1999): 8961–66. http://dx.doi.org/10.1073/pnas.96.16.8961.
Full textDmitrieva, Renata I., Cruz A. Hinojos, Eric Boerwinkle, Michael C. Braun, Myriam Fornage, and Peter A. Doris. "Hepatocyte Nuclear Factor 1 and Hypertensive Nephropathy." Hypertension 51, no. 6 (June 2008): 1583–89. http://dx.doi.org/10.1161/hypertensionaha.108.110163.
Full textLannoy, Vincent J., Annie Rodolosse, Christophe E. Pierreux, Guy G. Rousseau, and Frédéric P. Lemaigre. "Transcriptional Stimulation by Hepatocyte Nuclear Factor-6." Journal of Biological Chemistry 275, no. 29 (May 12, 2000): 22098–103. http://dx.doi.org/10.1074/jbc.m000855200.
Full textWang, Kewei, and Ai-Xuan Holterman. "Pathophysiologic role of hepatocyte nuclear factor 6." Cellular Signalling 24, no. 1 (January 2012): 9–16. http://dx.doi.org/10.1016/j.cellsig.2011.08.009.
Full textYue, H.-Y., C. Yin, J.-L. Hou, X. Zeng, Y.-X. Chen, W. Zhong, P.-F. Hu, et al. "Hepatocyte nuclear factor 4α attenuates hepatic fibrosis in rats." Gut 59, no. 2 (August 10, 2009): 236–46. http://dx.doi.org/10.1136/gut.2008.174904.
Full textBulla, G. A. "Hepatocyte nuclear factor-4 prevents silencing of hepatocyte nuclear factor-1 expression in hepatoma x fibroblast cell hybrids." Nucleic Acids Research 25, no. 12 (June 1, 1997): 2501–8. http://dx.doi.org/10.1093/nar/25.12.2501.
Full textERICKSON, Roger H., James R. GUM, Craig D. LOTTERMAN, James W. HICKS, Roy S. LAI, and Young S. KIM. "Regulation of the gene for human dipeptidyl peptidase IV by hepatocyte nuclear factor 1α." Biochemical Journal 338, no. 1 (February 8, 1999): 91–97. http://dx.doi.org/10.1042/bj3380091.
Full textWu, Zhi-Tao, Dan Yao, Shu-Yi Ji, Xuan Ni, Yi-Meng Gao, Li-Jian Hui, and Guo-Yu Pan. "Optimized Hepatocyte-Like Cells with Functional Drug Transporters Directly-Reprogrammed from Mouse Fibroblasts and their Potential in Drug Disposition and Toxicology." Cellular Physiology and Biochemistry 38, no. 5 (2016): 1815–30. http://dx.doi.org/10.1159/000443120.
Full textLiu, Hua, Hui Ren, and Brett T. Spear. "The Mouse Alpha-Albumin (Afamin) Promoter Is Differentially Regulated by Hepatocyte Nuclear Factor 1α and Hepatocyte Nuclear Factor 1β." DNA and Cell Biology 30, no. 3 (March 2011): 137–47. http://dx.doi.org/10.1089/dna.2010.1097.
Full textHadzopoulou-Cladaras, Margarita, Elena Kistanova, Catherine Evagelopoulou, Shengyou Zeng, Christos Cladaras, and John A. A. Ladias. "Functional Domains of the Nuclear Receptor Hepatocyte Nuclear Factor 4." Journal of Biological Chemistry 272, no. 1 (January 3, 1997): 539–50. http://dx.doi.org/10.1074/jbc.272.1.539.
Full textNikolaidou-Neokosmidou, Varvara, Vassilis I. Zannis, and Dimitris Kardassis. "Inhibition of hepatocyte nuclear factor 4 transcriptional activity by the nuclear factor κB pathway." Biochemical Journal 398, no. 3 (August 29, 2006): 439–50. http://dx.doi.org/10.1042/bj20060169.
Full textNing, Bei-Fang, Jin Ding, Jiao Liu, Chuan Yin, Wen-Ping Xu, Wen-Ming Cong, Qing Zhang, et al. "Hepatocyte nuclear factor 4α-nuclear factor-κB feedback circuit modulates liver cancer progression." Hepatology 60, no. 5 (June 27, 2014): 1607–19. http://dx.doi.org/10.1002/hep.27177.
Full textBonzo, Jessica A., Christina H. Ferry, Tsutomu Matsubara, Jung-Hwan Kim, and Frank J. Gonzalez. "Suppression of Hepatocyte Proliferation by Hepatocyte Nuclear Factor 4α in Adult Mice." Journal of Biological Chemistry 287, no. 10 (January 12, 2012): 7345–56. http://dx.doi.org/10.1074/jbc.m111.334599.
Full textGonzalez, Frank J. "Regulation of Hepatocyte Nuclear Factor 4α-mediated Transcription." Drug Metabolism and Pharmacokinetics 23, no. 1 (2008): 2–7. http://dx.doi.org/10.2133/dmpk.23.2.
Full textMassa, F., S. Garbay, R. Bouvier, Y. Sugitani, T. Noda, M. C. Gubler, L. Heidet, M. Pontoglio, and E. Fischer. "Hepatocyte nuclear factor 1 controls nephron tubular development." Development 140, no. 4 (January 29, 2013): 886–96. http://dx.doi.org/10.1242/dev.086546.
Full textde Boussac, Hugues, Marcin Ratajewski, Iwona Sachrajda, Gabriella Köblös, Attila Tordai, Lukasz Pulaski, László Buday, András Váradi, and Tamás Arányi. "The ERK1/2-Hepatocyte Nuclear Factor 4α Axis Regulates HumanABCC6Gene Expression in Hepatocytes." Journal of Biological Chemistry 285, no. 30 (May 12, 2010): 22800–22808. http://dx.doi.org/10.1074/jbc.m110.105593.
Full textRausa, Francisco M., Yongjun Tan, Heping Zhou, Kyung W. Yoo, Donna Beer Stolz, Simon C. Watkins, Roberta R. Franks, Terry G. Unterman, and Robert H. Costa. "Elevated Levels of Hepatocyte Nuclear Factor 3β in Mouse Hepatocytes Influence Expression of Genes Involved in Bile Acid and Glucose Homeostasis." Molecular and Cellular Biology 20, no. 21 (November 1, 2000): 8264–82. http://dx.doi.org/10.1128/mcb.20.21.8264-8282.2000.
Full textNinomiya, Toshiaki, Hayashi Yoshitake, Saijoh Kiyofumi, Ohta Kyosuke, Yoon Seitetsu, Nakabayashi Hidekazu, Tamaoki Taiki, Kasuga Masato, and Itoh Hiroshi. "Expression ratio of hepatocyte nuclear factor-1 to variant hepatocyte nuclear factor-1 in differentiation of hepatocellular carcinoma and hepatoblastoma." Journal of Hepatology 25, no. 4 (October 1996): 445–53. http://dx.doi.org/10.1016/s0168-8278(96)80203-0.
Full textGuo, Hongtao, Chengjiang Gao, Zhiyong Mi, Philip Y. Wai, and Paul C. Kuo. "Phosphorylation of Ser158 regulates inflammatory redox-dependent hepatocyte nuclear factor-4α transcriptional activity." Biochemical Journal 394, no. 2 (February 10, 2006): 379–87. http://dx.doi.org/10.1042/bj20051730.
Full textWalesky, Chad, Sumedha Gunewardena, Ernest F. Terwilliger, Genea Edwards, Prachi Borude, and Udayan Apte. "Hepatocyte-specific deletion of hepatocyte nuclear factor-4α in adult mice results in increased hepatocyte proliferation." American Journal of Physiology-Gastrointestinal and Liver Physiology 304, no. 1 (January 1, 2013): G26—G37. http://dx.doi.org/10.1152/ajpgi.00064.2012.
Full textCourtois, G., S. Baumhueter, and G. R. Crabtree. "Purified hepatocyte nuclear factor 1 interacts with a family of hepatocyte-specific promoters." Proceedings of the National Academy of Sciences 85, no. 21 (November 1, 1988): 7937–41. http://dx.doi.org/10.1073/pnas.85.21.7937.
Full textHayhurst, Graham P., Ying-Hue Lee, Gilles Lambert, Jerrold M. Ward, and Frank J. Gonzalez. "Hepatocyte Nuclear Factor 4α (Nuclear Receptor 2A1) Is Essential for Maintenance of Hepatic Gene Expression and Lipid Homeostasis." Molecular and Cellular Biology 21, no. 4 (February 15, 2001): 1393–403. http://dx.doi.org/10.1128/mcb.21.4.1393-1403.2001.
Full textRawat, Siddhartha, and Michael J. Bouchard. "The Hepatitis B Virus (HBV) HBx Protein Activates AKT To Simultaneously Regulate HBV Replication and Hepatocyte Survival." Journal of Virology 89, no. 2 (October 29, 2014): 999–1012. http://dx.doi.org/10.1128/jvi.02440-14.
Full textDrewes, Thorsten, Annette Clairmont, Ludger Klein-Hitpass, and Gerhart U. Ryffel. "Estrogen-Inducible Derivatives of Hepatocyte Nuclear Factor-4, Hepatocyte Nuclear Factor-3 and Liver Factor B1 are Differently Affected by Pure and Partial Antiestrogens." European Journal of Biochemistry 225, no. 1 (October 1994): 441–48. http://dx.doi.org/10.1111/j.1432-1033.1994.00441.x.
Full textChou, Ho, Lai, Chen, Wu, Shun, Wen, and Lai. "B-Cell Activating Factor Enhances Hepatocyte-Driven Angiogenesis via B-Cell CLL/Lymphoma 10/Nuclear Factor-KappaB Signaling during Liver Regeneration." International Journal of Molecular Sciences 20, no. 20 (October 10, 2019): 5022. http://dx.doi.org/10.3390/ijms20205022.
Full textCheng, Chun-Chia, Wan-Yu Yang, Ming-Chen Hsiao, Kuan-Hao Lin, Hao-Wei Lee, and Chiou-Hwa Yuh. "Transcriptomically Revealed Oligo-Fucoidan Enhances the Immune System and Protects Hepatocytes via the ASGPR/STAT3/HNF4A Axis." Biomolecules 10, no. 6 (June 12, 2020): 898. http://dx.doi.org/10.3390/biom10060898.
Full textNaiki, Takafumi, Masahito Nagaki, Takahiko Asano, Takayuki Kimata, and Hisataka Moriwaki. "Adenovirus-mediated hepatocyte nuclear factor-4α overexpression maintains liver phenotype in cultured rat hepatocytes." Biochemical and Biophysical Research Communications 335, no. 2 (September 2005): 496–500. http://dx.doi.org/10.1016/j.bbrc.2005.07.102.
Full textMACHIDA, Tomohisa, Masanori YASUDA, Michio SIMIZU, Norihide MOCHIZUKI, Kenji KAWAI, Hitoshi ITOH, Hiroshi KAJIWARA, Naoya NAKAMURA, and Yoshiyuki OSAMURA. "Immunocytochemical hepatocyte nuclear factor-1.BETA. expression in effusions." Journal of the Japanese Society of Clinical Cytology 49, no. 4 (2010): 242–47. http://dx.doi.org/10.5795/jjscc.49.242.
Full textBellanné-Chantelot, Christine, Dominique Chauveau, Jean-François Gautier, Danièle Dubois-Laforgue, Séverine Clauin, Sandrine Beaufils, Jean-Marie Wilhelm, et al. "Clinical Spectrum Associated with Hepatocyte Nuclear Factor-1β Mutations." Annals of Internal Medicine 140, no. 7 (April 6, 2004): 510. http://dx.doi.org/10.7326/0003-4819-140-7-200404060-00009.
Full textSingh, Puja, Shu-Ping Tung, Eun Hee Han, In-Kyu Lee, and Young-In Chi. "Dimerization defective MODY mutations of hepatocyte nuclear factor 4α." Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 814 (March 2019): 1–6. http://dx.doi.org/10.1016/j.mrfmmm.2019.01.002.
Full textTaraviras, Stavros, Gunther SchuTz, and Gavin Kelsey. "Generation of Inhibitory Mutants of Hepatocyte Nuclear Factor 4." European Journal of Biochemistry 244, no. 3 (March 15, 1997): 883–89. http://dx.doi.org/10.1111/j.1432-1033.1997.00883.x.
Full textAntkowiak, Mark, and Richard M. Green. "Telomeres, p53, Hepatocyte Nuclear Factor 4α, and Liver Disease." Hepatology 72, no. 4 (October 2020): 1166–68. http://dx.doi.org/10.1002/hep.31454.
Full textKanazawa, T., A. Konno, Y. Hashimoto, and Y. Kon. "Expression of Hepatocyte Nuclear Factor 4α in Developing Mice." Anatomia, Histologia, Embryologia 38, no. 1 (February 2009): 34–41. http://dx.doi.org/10.1111/j.1439-0264.2008.00889.x.
Full textLazarevich, N. L., and D. V. Alpern. "Hepatocyte nuclear factor 4 in epithelial development and carcinogenesis." Molecular Biology 42, no. 5 (October 2008): 699–709. http://dx.doi.org/10.1134/s0026893308050075.
Full textGreen, Janelle, Dorit Naot, and Garth Cooper. "Hepatocyte nuclear factor 1 negatively regulates amylin gene expression." Biochemical and Biophysical Research Communications 310, no. 2 (October 2003): 464–69. http://dx.doi.org/10.1016/j.bbrc.2003.09.046.
Full textYokoyama, Atsushi, Shogo Katsura, Ryo Ito, Waka Hashiba, Hiroki Sekine, Ryoji Fujiki, and Shigeaki Kato. "Multiple post-translational modifications in hepatocyte nuclear factor 4α." Biochemical and Biophysical Research Communications 410, no. 4 (July 2011): 749–53. http://dx.doi.org/10.1016/j.bbrc.2011.06.033.
Full textCao, Henian, and Robert A. Hegele. "Human hepatocyte nuclear factor-1β (HNF1B) 1968A/G polymorphism." Journal of Human Genetics 45, no. 2 (March 2000): 98–99. http://dx.doi.org/10.1007/s100380050021.
Full textChandra, Shubhra, Srilakshmi Srinivasan, and Jyotsna Batra. "Hepatocyte nuclear factor 1 beta: A perspective in cancer." Cancer Medicine 10, no. 5 (February 13, 2021): 1791–804. http://dx.doi.org/10.1002/cam4.3676.
Full textLiu, Hailing, Brett E. Jones, Cynthia Bradham, and Mark J. Czaja. "Increased cytochrome P-450 2E1 expression sensitizes hepatocytes to c-Jun-mediated cell death from TNF-α." American Journal of Physiology-Gastrointestinal and Liver Physiology 282, no. 2 (February 1, 2002): G257—G266. http://dx.doi.org/10.1152/ajpgi.00304.2001.
Full textBingle, C. D., B. P. Hackett, M. Moxley, W. Longmore, and J. D. Gitlin. "Role of hepatocyte nuclear factor-3α and hepatocyte nuclear factor-3β in Clara cell secretory protein gene expression in the bronchiolar epithelium." Biochemical Journal 308, no. 1 (May 15, 1995): 197–202. http://dx.doi.org/10.1042/bj3080197.
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