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Journal articles on the topic 'Hepatitis C Social aspects'

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Published: 10 December 2022

Last updated: 29 January 2023

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1

Kosagovskaya, I. I., and E. V. Volchkova. "THE MEDICO-SOCIAL ASPECTS OF VIRAL HEPATITIDES WITH THE PARENTERAL WAY OF TRANSMISSION." Epidemiology and Infectious Diseases 18, no. 1 (February 15, 2013): 28–39. http://dx.doi.org/10.17816/eid40715.

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The article is devoted to current epidemiological, social and economic aspects of parenteral viral hepatitis B and C. Statistical data on the incidence, prevalence, outcomes for viral hepatitides are provided. Prior medical and social factors influencing the formation of the epidemiological situation and the activity of infection with viral hepatitis B and C, including gaining the importance of the prevalence of parenterally transmitted viral hepatitis among drinkers, drug users, and HIV infected cases have been analyzed. The issues of economic losses and economic costs required to treat patients with viral hepatitis at various stages of infection were exhaustively covered. On the base of international recommendations a list of medical and social activities for prevention of chronic viral hepatitis B and C was given, the ways to reduce the prevalence of these socially significant diseases were proposed.

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Khurshid, Muhammad Adil, Manzoor Ahmad Naeem, and Sohail Hassan. "HEPATITIS C VIRUS (HCV)." Professional Medical Journal 25, no. 04 (April 10, 2018): 489–91. http://dx.doi.org/10.29309/tpmj/2018.25.04.333.

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Objectives: This study was carried out to find out the frequency of Hepatitis CVirus (HCV) infection in patients with end stage renal disease requiring Haemodialysis and theirrate of seroconversion to HCV positive during Haemodialysis in special subgroup population,the labour class of Punjab Pakistan. Study Designs: Cross-sectional descriptive study. Place &Duration: Haemodialysis Unit Nawaz Sharif Social Security Hospital, Multan Road Lahore fromJanuary 2009 through December 2012. Material and Method: A total of 92 patients, aged 15to 70 years belonging to Labour class of the Punjab were included in the study, who reportedfor Haemodialysis in our unit. All the patients were tested for the presence of HCV antibodyby rapid immunochromatographic technique (ICU devices) and also confirmed with EnzymeLinked Immunosorbant Assay (ELIZA) at the start of Haemodialysis and thereafter quarterly fortheir conversion to HCV positive state. Results: Out of 92 patients 34 (39.96%) were positivefor HCV Antibody 3 patients (3.26%) were positive for HbsAg where as 55 patients (59.78%)were negative for HbsAg or HCV Antibody. Out of 55 patients negative for HCV, 12 patientswere converted to HCV positive state within 18 months of Haemodialysis. Conclusion: A highincidence of HCV positive, 36.96 % was noted with a high seroconversion rate of 21.82 %toHCV positive. This study supports the idea that better socioeconomic status and awareness ofpreventive health aspects remains the corner stone for prevention and spread of HCV infection.

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Yakupova, F. M., R. V. Garipova, F. S. Gilmullina, J. M. Sozinova, and M. M. Zagidov. "Viral hepatitis B and C as occupational diseases." Medical Herald of the South of Russia 13, no. 4 (January 1, 2023): 39–44. http://dx.doi.org/10.21886/2219-8075-2022-13-4-39-44.

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Objective: to study the clinical and epidemiological features and medical and social aspects of viral hepatitis B and C in medical workers. Materials and methods: analysis of outpatient and inpatient records of medical workers with a diagnosis of chronic viral hepatitis B, C, B + C, B + D of various stages and degrees of activity, registered at the Republican Center of Occupational Pathology of the Republic of Tatarstan and the consultative and diagnostic department of the Republican Infectious Clinical Hospital named after prof. A.F. Agafonov. An on-line sociological survey of medical workers and senior students of medical universities in Kazan was conducted using the Google form. Results: medical personnel whose work is associated with the provision of invasive medical interventions are at the highest risk of infection with blood-borne infections. All medical workers had a history of accidents - needle sticks, cuts, blood spatter. The development of liver cirrhosis and the presence of lethal outcomes in liver cirrhosis decompensation reflect the general problem of chronic hepatitis C - the lack of timely effective antiviral therapy, despite the detection of hepatitis viruses in medical workers in the early stages of infection during periodic medical examinations. Conclusions: in the structure of occupational morbidity among healthcare workers in Tatarstan, viral hepatitis makes up 16.7%. There is still a risk of viral hepatitis infection in MRs of any level of education and status, including students of medical universities during work practice, assistance on a volunteer basis. Vaccination/revaccination against viral hepatitis B is regulated by regulations and shown to all healthcare workers with viral hepatitis C.

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Iakovenko, Nataliia O., Maksim Y. Zak, Mykola O. Klymenko, Svetlana V. Zhuk, and Olena K. Nuzhna. "METHODS OF TRANSMISSION AND FEATURES OF THE COURSE OF HEPATITIS C VIRUS INFECTION IN CHILDREN: MEDICAL AND SOCIAL ASPECTS." Wiadomości Lekarskie 72, no. 5 (2019): 928–32. http://dx.doi.org/10.36740/wlek201905137.

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Introduction: Hepatitis C virus (HCV) infection is a major global problem. According to WHO, 150-200 million people globally have hepatitis C infection. Even though HCV infection morbidity rate in children is relatively low in comparison with the adult population, approximately 5 million children in the world have active HCV. There is a number of differences between HCV infection in adults and in children. However, the data pertaining to this issue is controversial. The aim: Research, analysis and synthesis of information from contemporary literature on transmission of infection and characteristics of the course of HCV infection in children. Materials and methods: Analysis and synthesis of information from contemporary literature on transmission of infection and characteristics of the course of HCV infection in children were conducted. Conclusions: Information from literature of the latest years on peculiarities of infection, disease course and complications of HCV infection in children was analyzed and summarized in this article.

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De Farias, Cleilton Sampaio, Ricardo Antunes Dantas de Oliveira, and Maurício R. M. P. da Luz. "O mapa das hepatites virais no Acre: entre territórios e territorialidades." Revista Brasileira de Geografia Física 12, no. 6 (January 30, 2020): 2339. http://dx.doi.org/10.26848/rbgf.v12.6.p2339-2354.

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As hepatites virais são doenças causadas por vírus distintos (A, B, C e D), que têm em comum o acometimento particularmente forte do fígado humano. Objetivou-se mapear a distribuição das hepatites virais no Acre, no período de 2010 a 2014, por meio de dois indicadores. Esse mapeamento foi associado a proposições para explicar seus territórios, suas territorialidades e suas territorializações, sendo respectivamente os locais de maior ocorrência, as relações históricas e sociais que causaram essas enfermidades e a formação desses territórios. Em vista de tudo isto, as hepatites virais se territorializaram historicamente no Acre, possivelmente favorecidas por aspectos inadequados de vigilância epidemiológica, ligados com o controle de outras endemias que assolavam os municípios. Estes fatores, associados com as condições socioeconômicas e ambientais, com a desigualdade de renda, de escolaridade e de desenvolvimento humano desses espaços, permitiram que as relações que proporcionam a infecção e a transmissão dessas doenças fossem passadas de geração para geração. Esse processo resultou em territórios que apresentam, além de muitos casos notificados altas taxas de incidências como em Cruzeiro do Sul, Rio Branco, Tarauacá e Assis Brasil. The map of viral hepatitis in Acre: between territories and territorialities A B S T R A C TViral hepatitis are diseases caused by distinct viruses (A, B, C and D), which have in common the particularly strong involvement of the human liver. The objective of this study was to map the distribution of viral hepatitis in Acre between 2010 and 2014, using two indicators. This mapping was associated with propositions to explain their territories, their territorialities and their territorializations, being respectively the places of greatest occurrence, the historical and social relations that caused these diseases and the formation of these territories. In view of all this, viral hepatitis were historically territorialized in Acre, possibly favored by inadequate aspects of epidemiological surveillance, linked to the control of other endemic diseases that devastated the municipalities. These factors, associated with socioeconomic and environmental conditions, income inequality, schooling and human development of these spaces, allowed the relations that provide the infection and the transmission of these diseases were passed from generation to generation. This process resulted in territories that have, in addition to many cases reported high incidence rates such as Cruzeiro do Sul, Rio Branco, Tarauacá and Assis Brasil.Keywords: Viral hepatitis, Map, Territories, Acre.

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Raduto, O. I. "Medical social factors affecting the effectiveness of the treatment of viral hepatitis patients." Epidemiology and Infectious Diseases 19, no. 5 (October 15, 2014): 32–36. http://dx.doi.org/10.17816/eid40836.

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There was performed the analysis of modern epidemiological, social and financial aspects of the hepatitis C treatment. There was considered the influence of some factors on the efficacy of the treatment efficacy, in particular, the genetic status of patients, stage of the disease, the development of side effects and patient compliance with the treatment regimen. Social factors were shown to include also the patient's race, language barriers, being in prison, availability of the treatment. The effectiveness of treatment for this group ofpatients is also influenced by the gender, young age, the presence of mental illness in the patient, drug and alcohol abuse. Financial constraints contribute to the reducing the commitment of the drugs intaking, the deterioration of the health status of viral hepatitis C and B patients, respectively, higher total health expenditure for the health care. There was made a conclusion about the necessity of the work on the formation of the adherence of this category of patients to the treatment, the patient and doctor must work together to make a treatment decision, after careful discussion of the need to comply treatment and risks of side effects, as well as re-infection.

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Pourmarzi, Davoud, Andrew Smirnov, Lisa Hall, Gerard FitzGerald, and Tony Rahman. "‘I’m over the moon!’: patient-perceived outcomes of hepatitis C treatment." Australian Journal of Primary Health 26, no. 4 (2020): 319. http://dx.doi.org/10.1071/py20013.

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Understanding patient-perceived outcomes is crucial for assessing the effectiveness and acceptability of hepatitis C virus (HCV) treatment. This study aimed to explore patient-perceived outcomes of receiving direct-acting antivirals (DAAs). This study was a part of a mixed-methods case study of the Prince Charles Hospital program for improving access to HCV treatment in community settings. Data were collected using semi-structured interviews with nine patients who were in different stages of their treatment for HCV. The participants were recruited using purposive sampling. All interviews were audio-recorded, transcribed verbatim and analysed using thematic analysis. Patients emphasised ‘having more energy’ when reporting improvements in their physical health following treatment. They also reported a newly developed sense of freedom and hope. Improved physical and mental health empowered them to start a healthy lifestyle and to practise self-protection from the risk of re-infection. Patients highlighted their desire to help other patients to receive treatment, which was connected to their experience of the services that they received and their perceived health outcomes. Patients expect and experience various outcomes that are related to the physical, psychological and social aspects of living with, and being cured of HCV. Emphasis on the short-term outcomes of receiving HCV treatment may improve HCV treatment uptake and adherence rates.

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Orsini, Michael. "The Politics of Naming, Blaming and Claiming: HIV, Hepatitis C and the Emergence of Blood Activism in Canada." Canadian Journal of Political Science 35, no. 3 (September 2002): 475–98. http://dx.doi.org/10.1017/s0008423902778323.

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The term ''blood activism'' describes the range of collective challenges that arose among victims of Canada's tainted-blood scandal in the 1990s. This article examines the emergence of blood activism in Canada from the perspective of social movement theory, paying particular attention to the tensions between victims who contracted HIV through tainted blood and those who contracted Hepatitis C, the so-called ''forgotten victims'' of the tragedy. This study discusses how changes in the ''political opportunity structure''—loosely defined in the literature as aspects of the movement's external environment—influenced the nature of political action pursued by victims of tainted blood, the negotiation of the movement's collective identity and policy outcomes.

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MISHRA, RUCHIKA. "The Case of the Criminal Liver." Cambridge Quarterly of Healthcare Ethics 20, no. 1 (January 2011): 143. http://dx.doi.org/10.1017/s096318011000071x.

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Mr. C was a 62-year-old Chinese-American man suffering from end stage liver disease secondary to Hepatitis C. While on the waiting list for a liver, he was told that his current condition and MELD score were not advanced enough to expect a liver transplant for several years. Because of his chronic fatigue, he asked if there was any way to speed up the process but was told that was not possible.

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Mezzaroma, Ivano, Gianpiero D'Offizi, Elena Pinter, Rosetta Ferrara, Rosamaria Rosso, Emma Guerra, Giovanni Ricci, Maria Carta, Silvia Angelini, and Fernando Aiuti. "Immunological, Clinical and Epidemiological Aspects of an HIV-1 Positive Drug Abuser Cohort." Journal of Drug Issues 24, no. 4 (October 1994): 657–72. http://dx.doi.org/10.1177/002204269402400407.

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We analyzed a cohort of intravenous drug abusers with HIV-1 disease attending our institute in the years 1985–1993. We focused particular attention on the epidemiological analysis of patients, and their clinical, immunological and infectious conditions. The significance of biological markers, particulary CD4+ lymphocyte count and the occurence of other viral infections such as Cytomegalovirus, Epstein-Barr virus, Herpes Simplex virus and Hepatitis B and C viruses in the progress of HIV-1 disease were evaluated. At least two-thirds of the patients at different stages of HIV-1 were treated with antiretroviral drugs: zidovudine (AZT) from 1987 up to the present and more recently didanosine (DDI) alone or in combination with AZT. Psychological and behavioral aspects of our HIV-1 infected drug abusers, in particular needle exchange and condom use, were analyzed.

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Gross, Marielle S., Alexandra R. Ruth, and Sonja A. Rasmussen. "Respect women, promote health and reduce stigma: ethical arguments for universal hepatitis C screening in pregnancy." Journal of Medical Ethics 46, no. 10 (February 13, 2020): 674–77. http://dx.doi.org/10.1136/medethics-2019-105692.

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In the USA, there are missed opportunities to diagnose hepatitis C virus (HCV) in pregnancy because screening is currently risk-stratified and thus primarily limited to individuals who disclose history of injection drug use or sexually transmitted infection risks. Over the past decade, the opioid epidemic has dramatically increased incidence of HCV and a feasible, well-tolerated cure was introduced. Considering these developments, recent evidence suggests universal HCV screening in pregnancy would be cost-effective and several professional organisations have called for updated national policy. Historically, universal screening has been financially disincentivised on the healthcare system level, particularly since new diagnoses may generate an obligation to provide expensive treatments to a population largely reliant on public health resources. Here, we provide ethical arguments supporting universal HCV screening in pregnancy grounded in obligations to respect for persons, beneficence and justice. First, universal prenatal HCV screening respects pregnant women as persons by promoting their long-term health outside of pregnancy. Additionally, universal screening would optimise health outcomes within current treatment guidelines and may support research on treatment during pregnancy. Finally, universal screening would avoid potential harms of risk-stratifying pregnant women by highly stigmatised substance use and sexual behaviours.

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Dimitrijevic, I. K., C. S. Vucetic, N. K. Kalezic, D. R. Subotic, O. Z. Bojovic, and M. Z. Bumbasirevic. "Complications on skin and subcutaneous tissue among drug addicts caused by non sterile intravenous injections and burns." Acta chirurgica Iugoslavica 55, no. 4 (2008): 107–11. http://dx.doi.org/10.2298/aci0804107d.

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The use of psychoactive substances causes various consequences and is harmful for all organs. Some of the health consequences among intravenous drug users are HIV infections, hepatitis C, local tissue infections after drug injection, family, professional and social consequences. Through the world various harm reduction programs are established in order to educate drug users about safer drug injecting techniques, with the use of sterile needles and materials for disinfection of the drug injecting area. Authors presented epidemiological data, consequences on extremities after non sterile drug injecting and accidental burns, harm reduction programs as well as other guidelines in this field. In three case reports of intravenous drug addicts with surgical complications on the extremities and burns, surgical and anaesthesiological approaches were described. Special emphasis was given to preoperative preparations and the postoperative treatment as well as social- psychiatric aspect.

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13

Metwally, Ammal M., Dalia M. Elmosalami, Hazem Elhariri, Lobna A. El Etreby, Ahmed Aboulghate, Marwa M. El-Sonbaty, Amira Mohsen, et al. "Accelerating Hepatitis C virus elimination in Egypt by 2030: A national survey of communication for behavioral development as a modelling study." PLOS ONE 16, no. 2 (February 23, 2021): e0242257. http://dx.doi.org/10.1371/journal.pone.0242257.

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Aim of the work This study aimed at assessing the dominance of risk practices associated with HCV endemicity in Egypt and detecting the behavioral development level concerning different aspects of HCV risk behaviors with respect to age and gender. The survey highlights the most cost-effective strategies that could accelerate HCV elimination in Egypt. Subjects and methods A national household survey targeted 3780 individuals (age range: 10–85 years). The sample was a systematic probability proportionate to size from 6 governorates representing the six major subdivisions of Egypt. The indicators used for assessing the behavioral development level towards HCV included six domains: awareness (7 indicators), perceived risk (5 indicators), motivation with the intention to change (4 and 5 indicators for males and females respectively), trial, rejection or adoption (6 and 5 indicators for males and females respectively). Results The study revealed that along the continuum of behavior development, the percentage of the participants who acquired half of the scores was as follows: 73.1% aware, 69.8% developed perceived risk, 80.6% motivated with only 28.9% adopting the recommended behaviors, 32% rejected them, 2.3% were in the trial stage versus 35.8% who did not try any. Adolescents had significantly lower levels of development for almost all domains when compared to adults. Statistical higher significance was detected in favor of adults, employees, married, Lower Egypt governorates, and university-educated participants (p<0.001) regarding awareness, perceived risk, and motivation scores. More than half of the participants incorrectly believed that contaminated food, sharing food utilities, contaminated water, mosquitoes, and schistosomiasis would lead to HCV transmission. Conclusion Egypt would be closer to HCV elimination when cost-effective strategies are directed not towards creating awareness, perceived risk or motivation to change- (at an acceptable level)- but towards motivating adopting risk-reduction behaviors for HCV, tackling misconceptions and reinforcement of social support.

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Hashim, Ahmed, Margaret O’Sullivan, Hugh Williams, and Sumita Verma. "Developing a community HCV service: project ITTREAT (integrated community-based test – stage – TREAT) service for people who inject drugs." Primary Health Care Research & Development 19, no. 02 (December 4, 2017): 110–20. http://dx.doi.org/10.1017/s1463423617000731.

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Background and aims Majority of the individuals with hepatitis C virus (HCV) infection in England are people who inject drugs, a vulnerable and disenfranchised cohort with poor engagement with secondary care. Our aim is to describe our experiences in setting up a successful nurse led HCV service at a substance misuse service (SMS). Methods We justify the need for a community HCV service and review the different community based models. Our experiences in engaging with stakeholders, obtaining funding, service set up, challenges faced and key recommendations are discussed. Finally, a summary of interim clinical outcomes is presented. Results A successful community based “one-stop” nurse led HCV service was set up in Dec 2013 at a large SMS. It provides all aspects of care (blood borne virus screening, non-invasive assessment of hepatic fibrosis, Hepatology input, HCV treatment, peer mentor, social and psychiatrist support, and opiod substitution) at one site. Interim clinical data indicate high service uptake with HCV treatment outcomes comparable to secondary care. Conclusions The advent of direct acting antivirals provides a unique opportunity for HCV elimination in England by 2030. Our “one-stop” integrated and multidisciplinary community HCV model suggests that HCV care can be successfully delivered outside of a hospital setting and warrants national adoption.

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MAIN, J. "Hepatitis C: Clinical aspects." Journal of Infection 30, no. 2 (March 1995): 103–6. http://dx.doi.org/10.1016/s0163-4453(95)80003-4.

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El-Kassas, Mohamed, and Abeer Awad. "Metabolic aspects of hepatitis C virus." World Journal of Gastroenterology 28, no. 22 (June 14, 2022): 2429–36. http://dx.doi.org/10.3748/wjg.v28.i22.2429.

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McMichael, A. J. "Environmental and social influences on emerging infectious diseases: past, present and future." Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences 359, no. 1447 (July 29, 2004): 1049–58. http://dx.doi.org/10.1098/rstb.2004.1480.

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During the processes of human population dispersal around the world over the past 50 000–100 000 years, along with associated cultural evolution and inter–population contact and conflict, there have been several major transitions in the relationships of Homo sapiens with the natural world, animate and inanimate. Each of these transitions has resulted in the emergence of new or unfamiliar infectious diseases. The three great historical transitions since the initial advent of agriculture and livestock herding, from ca . 10 000 years ago, occurred when: (i) early agrarian–based settlements enabled sylvatic enzootic microbes to make contact with Homo sapiens ; (ii) early Eurasian civilizations (such as the Greek and Roman empires, China and south Asia) came into military and commercial contact, ca . 3000–2000 years ago, swapping their dominant infections; and (iii) European expansionism, over the past five centuries, caused the transoceanic spread of often lethal infectious diseases. This latter transition is best known in relation to the conquest of the Americas by Spanish conquistadores , when the inadvertent spread of measles, smallpox and influenza devastated the Amerindian populations. Today, we are living through the fourth of these great transitional periods. The contemporary spread and increased lability of various infectious diseases, new and old, reflect the combined and increasingly widespread impacts of demographic, environmental, behavioural, technological and other rapid changes in human ecology. Modern clinical medicine has, via blood transfusion, organ transplantation, and the use of hypodermic syringes, created new opportunities for microbes. These have contributed to the rising iatrogenic problems of hepatitis C, HIV/AIDS and several other viral infections. Meanwhile, the injudicious use of antibiotics has been a rare instance of human action actually increasing ‘biodiversity’. Another aspect of this fourth transition is that modern hyper–hygienic living restricts microbial exposure in early life. This, in the 1950s, may have contributed to an epidemic of more serious, disabling, poliomyelitis, affecting older children than those affected in earlier, more endemic decades. As with previous human–microbe transitions, a new equilibrial state may lie ahead. However, it certainly will not entail a world free of infectious diseases. Any mature, sustainable, human ecology must come to terms with both the need for, and the needs of, the microbial species that help to make up the interdependent system of life on Earth. Humans and microbes are not ‘at war’; rather, both parties are engaged in amoral, self–interested, coevolutionary struggle. We need to understand better, and therefore anticipate, the dynamics of that process.

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Mack, Heather, and Ian Paylor. "Hepatitis C and Social Work." British Journal of Social Work 46, no. 4 (March 4, 2015): 1115–30. http://dx.doi.org/10.1093/bjsw/bcv016.

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Gupta MD, Harsh, Bhupinder Singh MD, Nancy Gupta MD, and N. S. Neki MD, FRCP. "Social Media & Hepatitis C." International Journal of Current Research in Medical Sciences 4, no. 12 (December 30, 2017): 56–62. http://dx.doi.org/10.22192/ijcrms.2017.03.12.008.

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Diament, Decio. "Epidemiological aspects of hepatitis C in Brazil." Brazilian Journal of Infectious Diseases 11 (October 2007): 6–7. http://dx.doi.org/10.1590/s1413-86702007000700002.

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Barone, Antonio Alci. "Hepatitis C: virological aspects and practical implications." Brazilian Journal of Infectious Diseases 11 (October 2007): 12–13. http://dx.doi.org/10.1590/s1413-86702007000700005.

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McCashland, Timothy M. "Retransplantation for recurrent hepatitis C: Positive aspects." Liver Transplantation 9, no. 11 (November 2003): S67—S72. http://dx.doi.org/10.1053/jlts.2003.50249.

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Marinho, Rui T., Miguel C. Moura, Jose A. Giria, and Paulo Ferrinho. "EPIDEMIOLOGICAL ASPECTS OF HEPATITIS C IN PORTUGAL." Journal of Gastroenterology and Hepatology 16, no. 9 (September 2001): 1076–77. http://dx.doi.org/10.1046/j.1440-1746.2001.2574a.x.

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Kashyap, A. S. "Clinical Aspects of Chronic Hepatitis C Infection." JAMA: The Journal of the American Medical Association 290, no. 11 (September 17, 2003): 1452—b—1452. http://dx.doi.org/10.1001/jama.290.11.1452-c.

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Schattner, A. "Clinical Aspects of Chronic Hepatitis C Infection." JAMA: The Journal of the American Medical Association 290, no. 11 (September 17, 2003): 1453. http://dx.doi.org/10.1001/jama.290.11.1453-a.

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Leblebicioglu, H. "Clinical Aspects of Chronic Hepatitis C Infection." JAMA: The Journal of the American Medical Association 290, no. 11 (September 17, 2003): 1453—a—1453. http://dx.doi.org/10.1001/jama.290.11.1453-b.

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Bocec, Ana Simona, Alice Azoicăi, and Evelina Moraru. "Immunological aspects in viral hepatitis C in children." Pediatru.ro 1, no. 53 (2019): 20. http://dx.doi.org/10.26416/pedi.53.1.2019.2347.

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Artemova, M. G., and D. T. Abdurakhmanov. "Cryoglobulinemic vasculitis in chronic hepatitis C: Genetic aspects." Terapevticheskii arkhiv 89, no. 4 (April 15, 2017): 110–14. http://dx.doi.org/10.17116/terarkh2017894110-114.

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Cryoglobulinemia (CG) is detected in more than 50% of patients with chronic hepatitis C (CHC); however, only 15—25% of them develop cryoglobulinemic vasculitis (CV) that is a systemic vasculitis due to the formation of immune deposits, which affects small (less than medium-sized) vessels and which is frequently fatal for the patient. The causes of CG only in some patients with CHC and the pathogenesis of CV remain unstudied; however, the accumulated data allow one to identify the special contribution of the patient’s genetic factors to the development of the disease. The paper considers the genetic aspects of the development of CG and CV in CHC.

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Drochioi, Ana Simona, Evelina Moraru, Bogdan Diaconu, and Dan Cristian Moraru. "Hematological aspects in viral hepatitis C in children." Romanian Medical Journal 65, no. 3 (September 30, 2018): 196–201. http://dx.doi.org/10.37897/rmj.2018.3.7.

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Sumlivaia, O. N., M. S. Nevzorova, A. T. Sayfitova, and S. A. Vysotin. "Modern clinical laboratory aspects of chronic hepatitis C." Experimental and Clinical Gastroenterology, no. 7 (September 27, 2021): 37–42. http://dx.doi.org/10.31146/1682-8658-ecg-191-7-37-42.

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Aim. Assess the current diagnostic value of clinical laboratory markers of liver damage in chronic viral hepatitis C. Materials and methods. Comprehensive clinical examination of 194 patients with the diagnosis chronic hepatitis C and 73 almost healthy faces was conducted. Results. According to the clinical examination, 91% of patients have hepatomegaly. According to the results of elastography, the subgroup without fibrosis F0 49 (25%) people, with fibrosis of stages F1-F3-145 (75%) patients. The occurrence of HCV genotypes was: HCV-1-33%, HCV-2-12% and HCV-3-55%. The virusemia indicator showed large variations of values. During the research it was established that indirect indicators of a fibrosis of a liver: levels of AST and ALT, GGTP, a direct and general bilirubin, the APRI index are authentically exceeded by indexes of control group while the level of thrombocytes and de Ritis’s coefficient authentically decrease. Conclusions. The current course of chronic hepatitis C occurs with hepatomegalia, often associated with gastrointestinal and cardiovascular damage. The most common virus among patients is the HVC-3 genotype virus. When examining indirect markers of fibrosis in viral hepatitis C, the APRI test is an early predictor and has high predictive value. Platelet levels decrease with viral liver damage. As a consequence, the APRI index increases and the de Ritis ratio decreases.

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Hosseini Moghaddam, Seyed Mohammadmehdi, Seyed Moayed Alavian, and Mohammad Rahnavardi. "Therapeutic Aspects of Hepatitis C in Hemodialysis Patients." American Journal of Nephrology 29, no. 2 (2009): 123–28. http://dx.doi.org/10.1159/000151633.

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Atta, M. L. B. Sousa, P. E. Margarida, B. C. Leite, C. M. Pereira, R. Paran??, and A. M. Atta. "Autoimmune Aspects of Hepatitis C in Bahia (Brazil)." JCR: Journal of Clinical Rheumatology 12, Supplement (April 2006): S6. http://dx.doi.org/10.1097/01.rhu.0000217148.53598.0c.

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Anne Marie, COUROUCE, and BUSCH Michael. "Symposium S01 Hepatitis B and C - Biological aspects." Transfusion Clinique et Biologique 8 (June 2001): 7–8. http://dx.doi.org/10.1016/s1246-7820(01)00143-4.

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Flamm, S. L. "Clinical Aspects of Chronic Hepatitis C Infection--Reply." JAMA: The Journal of the American Medical Association 290, no. 11 (September 17, 2003): 1453—b—1454. http://dx.doi.org/10.1001/jama.290.11.1453-c.

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McGoldrick, Mary. "Hepatitis C." Home Healthcare Nurse 32, no. 6 (June 2014): 373. http://dx.doi.org/10.1097/nhh.0000000000000093.

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Zacks, Steven, Kimberly Beavers, Dickens Theodore, Karen Dougherty, Betty Batey, Jeremy Shumaker, Joseph Galanko, Roshan Shrestha, and Michael W. Fried. "Social Stigmatization and Hepatitis C Virus Infection." Journal of Clinical Gastroenterology 40, no. 3 (March 2006): 220–24. http://dx.doi.org/10.1097/00004836-200603000-00009.

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Irshad, M., I. Khushboo, Shiwani Singh, and Sukhbir Singh. "Hepatitis C Virus (HCV): A Review of Immunological Aspects." International Reviews of Immunology 27, no. 6 (January 2008): 497–517. http://dx.doi.org/10.1080/08830180802432178.

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Withers, NW, RC Hilsabeck, P. Malek-Ahmadi, and DA Hensley. "Psychosomatic aspects in liver disease I: chronic hepatitis C." Journal of Psychosomatic Research 55, no. 2 (August 2003): 120–21. http://dx.doi.org/10.1016/s0022-3999(03)00440-9.

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Roberts. "The economic aspects of hepatitis C - implications for haemophilia." Haemophilia 5, no. 6 (November 1999): 402–9. http://dx.doi.org/10.1046/j.1365-2516.1999.00363.x.

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Carra, R., G. Elia, N. Santangelo, B. A. Trovato, D. Rosso, E. Giunta, and R. Siciliano. "Hepatitis C virus genotypes in elderly patients with chronic hepatitis C." Archives of Gerontology and Geriatrics 22 (January 1996): 287–90. http://dx.doi.org/10.1016/0167-4943(96)86950-0.

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Grundy, Gillian, and Nicholas Beeching. "Understanding social stigma in women with hepatitis C." Nursing Standard 19, no. 4 (October 6, 2004): 35–39. http://dx.doi.org/10.7748/ns.19.4.35.s62.

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Grundy, Gillian, and Nicholas Beeching. "Understanding social stigma in women with hepatitis C." Nursing Standard 19, no. 4 (October 6, 2004): 35–39. http://dx.doi.org/10.7748/ns2004.10.19.4.35.c3720.

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Berezenko, V. S., and O. V. Tsaryova. "Clinical and paraclinical aspects of chronic hepatitis C in children." PERINATOLOGIYA I PEDIATRIYA, no. 2(62) (July 15, 2015): 38–42. http://dx.doi.org/10.15574/pp.2015.62.38.

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Elkholy, MostafaG, GamalT Shamma, MohammedE Enaba, and FatmaA Eldeeb. "Spotlight on some psychiatric aspects of hepatitis-C virus patients." Tanta Medical Journal 49, no. 2 (2021): 130. http://dx.doi.org/10.4103/tmj.tmj_34_18.

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Diallo, Salamata, Mariéme Polele Fall, Marie Louise Bassène, Mamadou Ngoné Gueye, Mame Aissé Thioubou, Cheikh Ahmadou Bamba Cissé, Alioune Badara Fall, Abdoul Aziz Atteib Fall, and Alsine Yauck. "Hepatitis C: Epidemiological, Clinical and Therapeutic Aspects in Dakar (Senegal)." Open Journal of Gastroenterology 12, no. 04 (2022): 98–106. http://dx.doi.org/10.4236/ojgas.2022.124010.

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Chew, Kara W., and Debika Bhattacharya. "Virologic and immunologic aspects of HIV–hepatitis C virus coinfection." AIDS 30, no. 16 (October 2016): 2395–404. http://dx.doi.org/10.1097/qad.0000000000001203.

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Rehermann, Barbara, and Michael P. Manns. "Immunologic aspects of acute and chronic hepatitis B and C." Current Opinion in Gastroenterology 12, no. 6 (November 1996): 554–59. http://dx.doi.org/10.1097/00001574-199611000-00011.

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Hilsabeck, Robin C., Steven A. Castellon, and Charles H. Hinkin. "Neuropsychological Aspects of Coinfection with HIV and Hepatitis C Virus." Clinical Infectious Diseases 41, Supplement_1 (July 1, 2005): S38—S44. http://dx.doi.org/10.1086/429494.

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Issaeva, N. "Hepatitis B and C: seroepidemiological aspects and modern prevention approach." Journal of Hepatology 34 (April 2001): 178. http://dx.doi.org/10.1016/s0168-8278(01)80653-x.

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Issaeva, N., A. Skovorodin, and O. Kanin. "Hepatitis B and C: seroepidemiological aspects and modern prevention approach." Journal of Hepatology 34 (April 2001): 178. http://dx.doi.org/10.1016/s0168-8278(01)81528-2.

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