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Journal articles on the topic "Hemostatic mateial"

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Ribalta, Teresa, Ian E. McCutcheon, Antonio G. Neto, Deepali Gupta, A. J. Kumar, David A. Biddle, Lauren A. Langford, Janet M. Bruner, Norman E. Leeds, and Gregory N. Fuller. "Textiloma (Gossypiboma) Mimicking Recurrent Intracranial Tumor." Archives of Pathology & Laboratory Medicine 128, no. 7 (July 1, 2004): 749–58. http://dx.doi.org/10.5858/2004-128-749-tgmrit.

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Abstract Context.—Resorbable substances used to achieve hemostasis during neurosurgical procedures comprise 3 principal classes based on chemical composition: (1) gelatin sponge, (2) oxidized cellulose, and (3) microfibrillar collagen. Nonresorbable hemostatic aides include various forms of cotton and rayon-based hemostats (cottonoids and kites). Resorbable and nonresorbable hemostatic agents have been reported to cause symptomatic mass lesions, most commonly following intra-abdominal surgery. Histologic examination typically shows a core of degenerating hemostatic agent surrounded by an inflammatory reaction. Each agent exhibits distinctive morphologic features that often permit specific identification. Hemostat-associated mass lesions have been variously referred to as textilomas, gossypibomas, gauzomas, or muslinomas. Objectives.—The aims of this study were to (1) identify cases of histologically proven cases of textiloma in neurosurgical operations, (2) characterize the specific hemostatic agent associated with textiloma formation, and (3) characterize the preoperative magnetic resonance imaging appearance of textiloma. Design.—Cases in which a textiloma constituted the sole finding on repeat surgery for recurrent brain tumor, or was a clinically significant component of a radiologically identified mass lesion together with residual tumor, constituted the study set. Results.—Five textilomas were identified and evaluated. The primary neoplasm was different in each case and included pituitary adenoma, tanycytic ependymoma, anaplastic astrocytoma, gliosarcoma, and oligodendroglioma. In all cases, preoperative magnetic resonance imaging suggested recurrent tumor. Textilomas included all categories of resorbable hemostatic agent. Other foreign bodies were present in some cases; the origin of these foreign bodies was traced to fibers shed from nonresorbable hemostatic material placed temporarily during surgery and removed before closure (cottonoids and kites). Inflammatory reactions included giant cells, granulomas, and fibroblastic proliferation. Microfibrillar collagen (Avitene) textilomas were associated with a striking eosinophil infiltration that was not seen with any other hemostatic agent. Conclusions.—Hemostatic agents may produce clinically symptomatic, radiologically apparent mass lesions. When considering a mass lesion arising after intracranial surgery, the differential diagnosis should include textiloma along with recurrent tumor and radiation necrosis.
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Wang, Qinghua, Jingwei Chen, Dexiang Wang, Minghui Shen, Huilong Ou, Jing Zhao, Ming Chen, Guoliang Yan, and Jun Chen. "Rapid Hemostatic Biomaterial from a Natural Bath Sponge Skeleton." Marine Drugs 19, no. 4 (April 15, 2021): 220. http://dx.doi.org/10.3390/md19040220.

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Uncontrolled bleeding is the main cause of mortality from trauma. Collagen has been developed as an important hemostatic material due to its platelet affinity function. A bath sponge skeleton is rich in collagen, also known as spongin. To understand the hemostatic effect of spongin, spongin materials, SX, SFM and SR were prepared from the bath sponge Spongia officinalis, and hemostatic experiments were performed. The SX, SFM and SR were significantly better than the positive control, type I collagen, in shortening the whole blood clotting time in vitro and hemostasis upon rat tail amputation. In a hemostatic experiment of rabbit common carotid artery injury, the hemostatic time and 3 h survival rate of the SFM group were 3.00 ± 1.53 min and 100%, respectively, which are significantly better than those of the commercial hemostat CELOX-A (10.33 ± 1.37 min and 67%, respectively). Additionally, the SFM showed good coagulation effects in platelet-deficient blood and defibrinated blood, while also showing good biocompatibility. Through a variety of tests, we speculated that the hemostatic activity of the SFM is mainly caused by its hyperabsorbency, high affinity to platelets and high effective concentration. Overall, the SFM and spongin derivates could be potential hemostatic agents for uncontrolled bleeding and hemorrhagic diseases caused by deficiency or dysfunction of coagulation factors.
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Sharma, Saurabh, Tejraj P. Kale, Lingaraj J. Balihallimath, and Abhishek Motimath. "Evaluating Effectiveness of Axiostat Hemostatic Material in achieving Hemostasis and Healing of Extraction Wounds in Patients on Oral Antiplatelet Drugs." Journal of Contemporary Dental Practice 18, no. 9 (2017): 802–6. http://dx.doi.org/10.5005/jp-journals-10024-2130.

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ABSTRACT Aim The aim of this study was to evaluate the efficacy of Axiostat Hemostatic Dental dressing in achieving hemostasis postextraction and determining its effect on pain and healing of the extraction wound, compared with control, i.e., conventional method of extraction in patients on oral antiplatelet therapy. Materials and methods Totally, 40 patients on oral antiplatelet drugs were included in the study and overall 80 extractions were done applying split mouth study design, without altering patient's drug regime. Extraction sites were divided into two groups: Group I received Axiostat Hemostatic Dental Dressing (study site), and group II received conventional method; pressure pack with sterile gauze under biting pressure followed by suturing if required (control site) was used to attain hemostasis. Results Extraction sites treated with Axiostat Hemostatic Dressing achieved hemostasis earlier (mean 1 minute 13 seconds) compared with control sites (mean = 14 minutes 1 second), which was also statistically significant (p < 0.001). Postoperative pain was considerably lower and significantly better healing was seen in the study group (p < 0.001) compared with the control. Conclusion Axiostat demonstrated to be an effective hemostatic agent that considerably lessens the bleeding time in patients on oral antiplatelet drugs postextraction. In addition, it even offered minimal postoperative pain and improved healing of the extraction wound. On comparing the results of this study with our study on HemCon Dental Dressing, Axiostat Dental Dressing (ADD) is found to be as effective and at par in achieving hemostasis in patients on oral antiplatelet therapy. Clinical significance The past few decades have seen an upsurge in use of low-dose aspirin either alone or in combination with other drugs. When these patients require dental/maxillofacial treatment, earlier concept of stopping these medications is associated with increased risk of thromboembolic event. The present study highlights an alternative approach using ADD which aids in quick hemostasis, accentuates healing, and reduce postoperative pain. How to cite this article Sharma S, Kale TP, Balihallimath LJ, Motimath A. Evaluating Effectiveness of Axiostat Hemostatic Material in achieving Hemostasis and Healing of Extraction Wounds in Patients on Oral Antiplatelet Drugs. J Contemp Dent Pract 2017;18(9):802-806.
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Nabavizadeh, Mohammad Reza, Arman Zargaran, Fariborz Moazami, Fatemeh Askari, Safoora Sahebi, Alireza Farhadpoor, and Pouya Faridi. "Comparison of the Hemostatic Activity of Quercus persica Jaub. & Spach. (Oak) With Ferric Sulfate in Bony Crypts." Journal of Evidence-Based Complementary & Alternative Medicine 21, no. 1 (June 30, 2015): 34–38. http://dx.doi.org/10.1177/2156587215593378.

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Effective tissue hemostasis in periapical surgical site is important in the procedures. Plants with large amount of tannins may act as a local hemostatic agent. We aimed to compare the hemostatic effect of the extract of Quercus persica with one of the common hemostatic material used in periapical surgery. Six standardized bone holes were prepared in the calvaria of 5 Burgundy rabbits. Two hemostatic medicaments were tested for their hemostatic effect and were compared with control defects: Group 1, cotton pellet soaked in 15.5% ferric sulfate solution; Group 2, cotton pellet soaked in pure ethanolic extract of Q. persica. Bleeding score between the groups was compared. The ferric sulfate group exhibited significantly less bleeding than the other 2 groups. Q. persica was found to cause more hemostasis than the control group at 4 and 5 minutes but there were no significant differences between normal saline and Q. persica extract in bleeding control.
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Zhang, Shiyao, Tingting Shi, Guangjun Wu, Qi Zhang, and Pibo Ma. "Preparation and property of soluble hemostatic material with 3D knitted structure." Journal of Industrial Textiles 52 (August 2022): 152808372211073. http://dx.doi.org/10.1177/15280837221107399.

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To solve the problems of low mechanical properties and poor coagulation effect of soluble hemostatic dressings, a new type of soluble hemostatic fabric with three-dimensional knitted structure is proposed in this paper. Three-dimensional knitted fabrics had good extension and porous structure. This three-dimensional soluble knitted fabric can be used for skin wounds clotting and healing. This paper mainly studied the influence of structural thickness on the performance of three-dimensional knitted dressings. Characterization analysis showed that three-dimensional knitted soluble hemostatic dressings had appropriate porosity and water vapor transmission rate (WVTR), and the fabric with the maximum thickness had good elongation (70.04%) and a very low blood clotting index (BCI) (11.18%). This suggests the potential application for soluble three-dimensional knitted structure fabric on skin wound hemostasis.
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Lin, Xiangwei, Yajing Shen, and Lidai Wang. "Multi-Scale Photoacoustic Assessment of Wound Healing Using Chitosan–Graphene Oxide Hemostatic Sponge." Nanomaterials 11, no. 11 (October 28, 2021): 2879. http://dx.doi.org/10.3390/nano11112879.

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Hemostasis is vital to save lives, reducing risks of organ failure and hemorrhagic shock. Exploring novel hemostatic materials and precise monitoring of the hemostatic status is of great importance for efficient hemostasis. We present the development of chitosan–graphene oxide-based hemostatic composite and multi-scale photoacoustic evaluation of the hemostatic performance. The hemostatic sponge can quickly and efficiently absorb the blood with its porous cavity and specific surficial property. We inspect the hemostatic performance via an in vitro blood absorption test and in vivo mouse bleeding injury experiments. Results show that the synthesized hemostatic sponge can not only absorb plasma in blood fast with its interior porous structure but also stimulate the interfacial reaction with erythrocytes and platelets. The superiority of multi-scale photoacoustic imaging for guiding, monitoring, and evaluating the hemostatic stages of sponges is demonstrated with high spatial resolution and great sensitivity at depths. Photoacoustic evaluation of a chitosan–graphene oxide-based hemostatic sponge has the potential to be transferred toward the clinical assessment of wound healing.
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Kerbl, Kurt, and Ralph V. Clayman. "Acute Hemostasis During Laparoscopic Procedures: Method for Intraoperative Application of Hemostatic Material." Journal of Urology 151, no. 1 (January 1994): 109–10. http://dx.doi.org/10.1016/s0022-5347(17)34883-8.

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Chen, Yeyi, Lei Wu, Pengpeng Li, Xiao Hao, Xiao Yang, Guanghui Xi, Wen Liu, Yakai Feng, Hongchao He, and Changcan Shi. "Polysaccharide Based Hemostatic Strategy for Ultrarapid Hemostasis." Macromolecular Bioscience 20, no. 4 (February 18, 2020): 1900370. http://dx.doi.org/10.1002/mabi.201900370.

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Li, Lin, Yan Du, Yi Xiong, Zhengwen Ding, Guoyu Lv, Hong Li, and Tielong Liu. "Injectable negatively charged gelatin microsphere-based gels as hemostatic agents for intracavitary and deep wound bleeding in surgery." Journal of Biomaterials Applications 33, no. 5 (October 18, 2018): 647–61. http://dx.doi.org/10.1177/0885328218807358.

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Gelatin, as natural macromolecular material, has been used in biomedical fields widely. In this study, various injectable gelatins A, B, and their compound AB microsphere-based gels (A-GMGs, B-GMGs and AB-GMGs) were prepared through water-in-oil emulsion method for hemostasis, and the effects of blood coagulation in vitro and surgical hemostasis (a deep liver wound model) in vivo were evaluated. Furthermore, the influences of gelatin sorts, the size of microsphere, zeta potential (ZP) and viscoelastic properties on hemostasis were also assessed. Results showed that the gelatin microspheres (GMs) exhibited smooth surface, good sphericity and the particle size of a rough normal distribution. GMs carried negative charges and their electronegativity was stronger than that of gelatin A (GA) and gelatin B (GB) raw materials. Rheological analysis showed that a decreasing particle size of the microspheres led to stronger gel strength, and solid-like gels were exhibited under low stress conditions and liquid-like gels were exhibited under high stress conditions. The blood clotting time of B-GMGs was within 60 s, which exhibited a significantly higher blood clotting effect compared with control groups. The hemostasis assay in vivo showed that the gels had better hemostatic effect on a deep liver wound bleeding model compared with control groups, especially B-GMGs. However, in vivo and vitro hemostatic experiments, particle size of GMs had no obvious influence on the hemostatic effect of the gels. In addition, the CCK-8 assay of bone marrow mesenchymal stem cells of murine (mMSCs) indicated non-cytotoxicity of GMs for cells. These results demonstrated that the gelatin microsphere-based gels (GMGs) had potential to be an effective hemostatic material for intracavitary and deep wound bleeding in surgery.
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Chen, Zihao, Lei Han, Changjun Liu, Yu Du, Xiao Hu, Ge Du, Chao Shan, et al. "A rapid hemostatic sponge based on large, mesoporous silica nanoparticles and N-alkylated chitosan." Nanoscale 10, no. 43 (2018): 20234–45. http://dx.doi.org/10.1039/c8nr07865c.

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Due to the designed, coagulation-promoting microstructure, a rapid and safe hemostat was developed and its hemostatic efficiency was evaluated by in vitro clotting tests and in vivo hemostatic analyses.
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Dissertations / Theses on the topic "Hemostatic mateial"

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Rush, Tabitha. "Hemostatic Mechanisms of Common Textile Wound Dressing Materials." NCSU, 2010. http://www.lib.ncsu.edu/theses/available/etd-03302010-230342/.

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The objective of this research is to develop a series of material treatments and modifications, and, using a standardized set of tests, determine the extent of the ability of the modified material to enhance coagulation. This research focuses on materials commonly used in traditional textile based wound dressings; utilizing Streaming Potential studies, Scanning Electron Microscopy (SEM) and Thrombin Assays. The materials tested can be classified into 4 groups: control materials, modified PLA, SAMs treated glass, and TEOS treated materials. The control materials included: spun cotton and rayon yarn; continuous filament Nylon, Polypropylene (PP), and Polyethylene terephthalate (PET); heat cleaned glass (control glass); and PLA staple fibers. Contact angle measurements showed that both the control glass and the PET showed an increase in contact angle when treated with TEOS. This corresponds to a decrease and no improvement, respectively, in thrombogenicity for these materials in the thrombin assay. The remaining materials tested showed no change or a decrease in contact angle after TEOS treatment, and a corresponding increase in thrombogenicity. These results support previous studies that indicate an increase in wettability contributes to the enhancement of coagulation (16). While the streaming potential studies showed no correlation between thrombin formation or contact angle data, these tests provided an important launching platform for future studies utilizing the Streaming Potential Jar. Future work could benefit from the use of more physiologically relevant solutions, such as CaCl2, NaCl, or other blood substitutes (15). While no definitive correlations between test methods were elucidated, the results garnered from this research created a strong launching platform from which future materials research can continue.
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Ananieva, V. V., and S. О. Petrov. "Justification of concentration of dry extracts from vegetable raw materials in the composition of dental gel." Thesis, Національний технічний університет "Харківський політехнічний інститут", 2019. http://repository.kpi.kharkov.ua/handle/KhPI-Press/45932.

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TAVARES, Leandro Henrique de Mesquita. "Esponja do biopolímero de cana-de-açúcar no tratamento de trauma renal extenso induzido em coelhos." Universidade Federal de Pernambuco, 2012. https://repositorio.ufpe.br/handle/123456789/18288.

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Introdução: A reconstrução do parênquima renal requer, em algumas situações, uma técnica cirúrgica mais complexa e delicada. O trauma renal de alto grau e as nefrectomias parciais para remoção de tumores malignos induzem a uma reconstrução renal de difícil execução e possuem um potencial elevado para causar perda completa do órgão. A utilização de substâncias auxiliares na reconstrução renal, tais como: selantes biológicos e hemostáticos têm fundamental importância para a sua preservação. OBJETIVO: Avaliar o efeito hemostático e selante da esponja do biopolímero da cana-de-açúcar em trauma renal de alto grau induzido em coelhos. MÉTODOS: Foi realizado um estudo experimental, prospectivo e pareado, com vinte e quatro unidades renais de doze coelhos da linhagem California. Após indução de trauma renal bilateral e de alto grau (lesão da via coletora), utilizamos, para a reconstrução e hemostasia do parênquima renal direito, a esponja do biopolímero da cana-de-açúcar, e à esquerda, foi utilizada a esponja de Surgifoam®. Nos dois lados, foi realizada uma sutura com fio de poliglactina 4/0 sobre as esponjas. Desta forma, cada coelho se tornou controle de si mesmo. Durante o procedimento cirúrgico, foram avaliados: o tempo cirúrgico total, o tempo para hemostasia e o grau de perda sanguínea. Os animais foram sacrificados após quatro semanas, sendo os rins retirados e encaminhados para a análise histológica. Foi avaliada a presença de fístulas, urinoma, hematomas e aderências aos órgãos adjacentes no momento da nefrectomia. A análise histológica observou o grau de inflamação e fibrose, assim como presença de necrose. RESULTADOS: Em relação ao tamanho dos rins, não houve diferença estatística entre os grupos (p=0,058), o que configura uma homogeneidade entre eles. Da mesma forma, o tempo para hemostasia foi similar (p=0,195) e a perda sanguínea (p=0,480). Por outro lado, foi notada uma maior incidência de aderências aos órgãos adjacentes no grupo do BCPA, assim como, uma maior intensidade da resposta inflamatória a corpo estranho (p=0,004). Todavia, sem influência nos resultados finais. Não foi evidenciada a ocorrência de hemorragia maciça, formação de hematomas, abscessos, fístulas ou cálculos em nenhuma das unidades renais. A presença de fibrose e necrose foi semelhante nos dois grupos do ponto de vista estatístico (p=0,500 e 0,414, respectivamente). CONCLUSÃO: A esponja do biopolímero da cana-de-açúcar demonstrou eficácia em relação ao controle hemostático e selante sobre o parênquima renal de coelhos, sem causar complicações importantes. Futuros estudos podem direcionar seu uso rotineiro na prática urológica.
Introduction: The reconstruction of the renal parenchyma requires, in some situations, a surgical technique more complex and delicate. The high grade renal trauma and partial nephrectomy for removal of malignant tumors induce a kidney reconstruction difficult to implement and have a high potential to cause complete loss of the organ. The use of auxiliary substances in renal reconstruction, such as biological sealants and hemostatic are of enormous value to their preservation. Objective: To evaluate the effect of sealant and hemostatic sponge biopolymer of sugarcane in high grade renal trauma induced in rabbits. Methods: We conducted an experimental study, prospective, matched, with twenty-four renal units of twelve rabbits from California lineage. After induction of bilateral renal trauma and high-grade lesions, it was used for the reconstruction of right renal parenchymal, the biopolymer sponge of cane sugar, and in left kidney, we used the sponge Surgifoam®. On both sides, we performed a suture with polyglactin 4/0 on the sponges. Thus, each rabbit has control of himself. During surgery, we evaluated the total surgical time, time to hemostasis and the degree of blood loss. The animals were sacrificed after four weeks, and the kidneys removed and sent for histological analysis. We evaluated the presence of fistula, urinoma, hematoma, and adhesions to adjacent organs at the time of nephrectomy. Histological analysis showed the degree of inflammation and fibrosis, as well as necrosis. Results: In relation to the size of the kidneys, there was no statistical difference between groups (p = 0.058), which is one commonality between them. Similarly, time to hemostasis was similar (p = 0.195) and blood loss (p = 0.480). Moreover, it was noted an increased incidence of adhesions to adjacent organs in BCPA group, as well as a greater inflammatory response to foreign bodies (p = 0.004). However, no influence on final results. There was no evidence the occurrence of massive bleeding, hematomas, abscesses, fistulas, or in any calculations of renal units. The presence of fibrosis and necrosis was similar in both groups a statistically (p = 0.500 and 0.414, respectively). Conclusion: The biopolymer sponge of sugarcane has shown efficacy in the hemostatic control and sealant on the renal cortex of rabbits, without causing major complications. Future studies may direct its routine use in urologic practice.
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Walker, Anne. "Exploiting Protein- and Synthetic Polymer-Based Materials for Use in Tunable Biological Mimics and Devices." Case Western Reserve University School of Graduate Studies / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=case1554508268871554.

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Antovic, Aleksandra. "Determinations of the overall haemostasis potential and fibrin gel permeability : method development and application in research and in clinical materials /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7349-932-3/.

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Meade, Eliza. "Hypoxic Regulation of VEGF and PAI-1 Expression by HIF-1[alpha] and HIF-2[alpha] in First Trimester Trophoblasts." Yale University, 2006. http://ymtdl.med.yale.edu/theses/available/etd-06282006-115727/.

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Preeclampsia results from incomplete trophoblast invasion of the spiral arteries during early pregnancy. Vascular endothelial growth factor (VEGF) and plasminogen activator inhibitor-1 (PAI-1) are critical factors involved in angiogenesis, invasion and hemostasis at the maternal-fetal interface. Both factors are transcriptionally regulated by hypoxia inducible factor (HIF), a heterodimeric complex consisting of HIF-1[beta] and either HIF-1[alpha] or -2[alpha] whose specificity or redundancy in gene regulation is cell-type specific. This study uses siRNA technology to dissect the mechanisms of hypoxia-mediated regulation of PAI-1 and VEGF expression in first trimester trophoblasts. Immortalized first trimester human extravillous trophoblasts (HTR8/SVneo cells) were maintained in serum-free and serum-containing media for 4h (n=3-4), 8h (n=6), 24h (n=5) and 48h (n=5) under normoxic (21% O2) and hypoxic (1-2% O2) conditions to determine a time of maximum induction of both VEGF and PAI-1. Subsequently, cells were maintained for 48h in the presence or absence of siRNA for HIF-1[alpha], HIF-2[alpha], HIF-1[alpha] + -2[alpha], a non-targeting (NT) sequence or Cyclophilin B (CB). Media were then removed, cells lysed, and Western blotting used to assess HIF-[alpha] knockdown. VEGF and PAI-1 levels in the media were quantified by ELISA and results expressed as pg or ng/[micro]g protein. Results from 3 to 8 independent experiments were analyzed using unpaired t-tests. Under hypoxic conditions treatment of cells with HIF-1[alpha], HIF-2[alpha] or HIF -1[alpha] + -2[alpha] siRNA resulted in >90% HIF-Ñ protein knockdown as determined by Western blotting. 48h of hypoxic treatment caused a statistically significant increase in PAI-1 levels (p<0.01) and VEGF levels (p<0.001) compared to normoxic controls. Under hypoxic conditions, PAI-1 levels were 4.75 [plus-minus] 0.46 ng/[micro]g protein and VEGF levels were 7.27 [plus-minus] 1.08 pg/[micro]g protein. Treatment with siRNA to HIF-1[alpha], HIF-2[alpha] and HIF-1[alpha] + -2[alpha] significantly reduced PAI-1 levels to 3.3 [plus-minus] 0.35 (p<0.02), 3.1 [plus-minus] 0.38 (p<0.03) and 2.4 [plus-minus] 0.19 (p<0.003), respectively. No significant difference in PAI-1 reduction was noted between the three HIF siRNA conditions. Under hypoxic conditions, levels of VEGF in cells treated with siRNA to HIF-1[alpha] (5.79 [plus-minus] 0.55), HIF-2[alpha] (5.50 [plus-minus] 1.24) and HIF-1[alpha] + -2[alpha] (4.24 [plus-minus] 0.93) were reduced compared to the hypoxic control (7.27 [plus-minus] 1.08), yet these effects did not reach statistical significance. However, when compared with the levels observed in cells treated with NT siRNA (9.90 [plus-minus] .98), all HIF siRNA treatments promoted a significant reduction in VEGF expression (p<0.003, p<0.02 and p<0.003 for HIF-1[alpha], HIF-2[alpha] and HIF-1[alpha]+ -2[alpha], respectively). In conclusion, these results indicate that hypoxia-mediated changes in PAI-1 and VEGF expression in trophoblasts are regulated similarly by both HIF-1[alpha] and HIF-2[alpha]. This provides important insight into the molecular mechanisms regulating hemostasis and trophoblast invasion as well as their potential dysfunction in pregnancies complicated by preeclampsia
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Books on the topic "Hemostatic mateial"

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Henri, Bourg, and Lisle Amaury, eds. Biomaterials developments and applications. Hauppauge, N.Y: Nova Science Publishers, 2009.

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F, Williams D., ed. Blood compatibility. Boca Raton, Fla: CRC Press, 1987.

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Book chapters on the topic "Hemostatic mateial"

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Paidas, Michael J., and Nazli Hossain. "Maternal and Fetal Thrombocytopenia." In Hemostasis and Thrombosis in Obstetrics & Gynecology, 41–66. Oxford, UK: Wiley-Blackwell, 2011. http://dx.doi.org/10.1002/9781444328332.ch4.

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Friedman, Mark T., Kamille A. West, Peyman Bizargity, Kyle Annen, H. Deniz Gur, and Timothy Hilbert. "Dial M for Maternal Antibody." In Immunohematology, Transfusion Medicine, Hemostasis, and Cellular Therapy, 213–19. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-14638-1_29.

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Källén, Bengt. "Maternal Use of Anticoagulants or Hemostatic Drugs and Infant Congenital Malformations." In Maternal Drug Use and Infant Congenital Malformations, 65–72. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-17898-7_8.

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Duarte-Chavez, Rodrigo, Sagar Mehta, Janak Bahirwani, Ronak Modi, and Stanislaw Stawicki. "The Use of Biomaterials in Gastrointestinal Endoscopy." In Biosurgicals - The Next Frontier in Operative Approaches [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.94528.

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Gastrointestinal endoscopy has evolved to become a therapeutic resource for multiple pathologic conditions, utilizing many techniques, tools and materials from the field of conventional surgery. Thermal, mechanical or chemical modalities are often employed to expedite the process of hemostasis and achieve a stable coagulum. Thermocoagulation coupled with devices for mechanical hemostasis have been adapted successfully to endoscopy. Chemical hemostasis from biomaterials can be obtained from biologically active materials such as thrombin and fibrin, absorbable products such as gelatins, collagen and oxidized cellulose or synthetic products and inorganic powders. Aside from hemostatic properties, biomaterials are also appealing due to its ability to promote wound healing. However, the use of biomaterials has not been as widespread in endoscopy as in conventional surgery, mainly because of the constraint of delivering these materials through an endoscope. Over the last decade, the options for biomaterials have expanded and its incorporation in endoscopy has slowly increased. Although the cost of biomaterials is higher compared to traditional hemostatics, this may be offset by the potential benefits of decreased bleeding related complications, procedure time, hospital stay and blood transfusions. Biomaterials have demonstrated an improvement in clinical outcomes during conventional surgery. Nevertheless, more studies are required to extrapolate these benefits to endoscopy.
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Claude Petit-Me, Jean, Stanislaw P. Stawicki, Michael S. Firstenberg, and Evan Marlin. "Biosurgical Materials in Neurosurgical Applications: From Pioneers to Leaders." In Contemporary Applications of Biologic Hemostatic Agents across Surgical Specialties [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.95898.

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Hemostasis in neurosurgery has evolved significantly over the past few decades. New advances in hemostatic agents, some developed specifically with neurosurgical applications in mind, allowed for more effective control of difficult intraoperative bleeding. These agents vary in the mechanism of action and each may be indicated in different and often highly specific situations. Here we present a review of the most commonly used hemostatic agents, their mechanism of action and their indications. Focus is placed on key aspects and considerations regarding the use biosurgical materials in neurosurgery, with emphasis on clinical appropriateness and patient safety.
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Latańska, Ilona, Piotr Rosiak, Paulina Paul, Witold Sujka, and Beata Kolesińska. "Modulating the Physicochemical Properties of Chitin and Chitosan as a Method of Obtaining New Biological Properties of Biodegradable Materials." In Chitin and Chitosan - Physicochemical Properties and Industrial Applications [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.95815.

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Physical and chemical modifications of chitin and chitosan allow for obtaining new functional properties of the natural polymers. This is a particularly valuable feature for the design and manufacture of new materials for medical applications. Due to their wide and varied biological activity, chitin and chitosan materials are increasingly used as dressing materials with antibacterial and hemostatic properties and as materials accelerating the regeneration of damaged tissues because of stimulation of granulation tissue formation, re-epithelialization and reduction of the formation of scar tissue. In addition, chitosan derivatives have antifungal, antiviral, anticancer activity. The increasing use of chitin and chitosan also has a positive impact on the environment, as it is obtained as a result of chitin deacetylation, usually isolated from shellfish shells. The main source of chitin is waste coating of crustaceans. The annual natural reproducibility of chitin by biosynthesis is estimated at 2–3 billion tons. Our interest in the use of biodegradable biopolymers derived from chitin concerns the design, synthesis in laboratory scale, testing new material properties and the final implementation of new developments for industrial practice of new dressing materials useful in the treatment of bleeding wounds (haemostatic properties) as well as in the regeneration of wounds and ulcers of various etiologies. Examples of chitin-based dressing materials introduced by Tricomed SA are Medisorb R Ag, Medisorb R Membrane, Medisorb R Powder and Tromboguard®.
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Feldman, D. "Adhesion and Hemostasis in Surgery." In Encyclopedia of Materials: Science and Technology, 38–43. Elsevier, 2001. http://dx.doi.org/10.1016/b0-08-043152-6/00007-3.

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Dammann, Kyle, Amanda Gifford, Kathryn Kelley, and Stanislaw P. Stawicki. "Operative Hemostasis in Trauma and Acute Care Surgery: The Role of Biosurgical Agents." In Biosurgicals - The Next Frontier in Operative Approaches [Working Title]. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.94100.

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Trauma and acute care surgery (TACS) constitutes the foundation of emergency surgical services in the United States. Blunt and penetrating traumatic injuries are a leading cause of death worldwide. Non-trauma general surgical emergencies are also a major source of morbidity and mortality. Operative interventions performed within the scope of TACS often revolve around the core principles of contamination control, hemostasis, surgical repair, and subsequent functional restoration. Hemorrhage control is an integral part of emergent operative interventions, and while most instances of surgical bleeding require direct suture ligation or some other form of direct tissue intervention, some circumstances call for the use of adjunctive means of hemostasis. This is especially applicable to situations and settings where direct applications of surgical energy, suture ligation, or direct compression are not possible. Difficult-to-control bleeding can be highly lethal and operative control can be very challenging when confounded by the lethal triad of acidosis, coagulopathy and hypothermia. Topical biosurgical materials (BSM) are of great value in such scenarios, and their use across a variety of settings, from pre-hospital trauma application to emergency general surgery operations, represents an important adjunct to improve patient outcomes. Here we present the different BSMs, discuss their various uses, and provide insight on future applications and developments in this important area.
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Conference papers on the topic "Hemostatic mateial"

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LI, Yan-ming, Zhen-zhen LIANG, and Yan SONG. "Application of Absorbable Hemostatic Materials Observed in Thyroid Operation." In International Conference on Advanced Material Science and Engineeering (AMSE2016). WORLD SCIENTIFIC, 2016. http://dx.doi.org/10.1142/9789813141612_0077.

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Shaji, Shyna, and Lynda V. Thomas. "A chitosan-gelatin hemostatic wound dressing- in-vitro functional evaluation studies in comparison with a commercially available hemostatic dressing." In INTERNATIONAL CONFERENCE ON SCIENCE AND TECHNOLOGY OF ADVANCED MATERIALS: STAM 20. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0016812.

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Liu, Mengyuan, Jian Yang, Jing Guan, Shujie Huang, Zhihong Li, and Miaolei Jing. "Effect of Grafted Chain Length on Hemostatic Activity of N-alkylated Chitosan." In 4th Annual International Conference on Material Engineering and Application (ICMEA 2017). Paris, France: Atlantis Press, 2018. http://dx.doi.org/10.2991/icmea-17.2018.53.

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Shakirov, M. N., R. I. Yulchiev, R. N. Dzhonibekova, M. M. Shakirov, and A. S. Lozhkomoev. "Assessment of the hemostatic activity of micro-mesoporous Fe2O3 nanostructures." In PROCEEDINGS OF THE INTERNATIONAL CONFERENCE ON PHYSICAL MESOMECHANICS. MATERIALS WITH MULTILEVEL HIERARCHICAL STRUCTURE AND INTELLIGENT MANUFACTURING TECHNOLOGY. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0034309.

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"Modification of Chitosan, a Kind of Marine Polymer Extracted from Shellfish, and Used for Hemostatic Material." In International Academy of Engineers. International Academy of Engineers, 2015. http://dx.doi.org/10.15242/iae.iae0215417.

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Li, Yanming, Yi Lu, and Aizhong Zhao. "Clinical Study of 200 Cases of Absorbable Hemostatic Gauze in Breast Cancer Surgery." In 2015 4th International Conference on Sensors, Measurement and Intelligent Materials. Paris, France: Atlantis Press, 2016. http://dx.doi.org/10.2991/icsmim-15.2016.153.

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Sivakumar, P., and Bhaarathi Dhurai. "An investigation on hemostatic suitability of macro and nano particles of sodium alginate, calcium alginate and chitosan for blood clotting bandages." In PROCEEDINGS OF ADVANCED MATERIAL, ENGINEERING & TECHNOLOGY. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0019647.

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Teja, J. L., S. A. Lopez-Haro, L. Leija, and A. Vera. "A finite element simulation of High Intensity Focused Ultrasound with polyacrylamide as coupling material for acoustic hemostasis." In 2013 Pan American Health Care Exchanges (PAHCE). IEEE, 2013. http://dx.doi.org/10.1109/pahce.2013.6568244.

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LI, Yan-ming, Zhen-zhen LIANG, and Chun-lei SONG. "Comparing the Effect of 3 Kinds of Different Materials on the Hemostasis of the Central Venous Catheter." In International Conference on Advanced Material Science and Engineeering (AMSE2016). WORLD SCIENTIFIC, 2016. http://dx.doi.org/10.1142/9789813141612_0082.

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Bezerra, Thaiane Fernanda Marques Barros, Eduarda Erika Ursulino Matos, Silvana Maria De Morais Campos, Carla Mikaela Brandão Santos, and Waleska Mendonça Paes Silva. "A IMPORTÂNCIA DA VITAMINA K COMO FATOR DE PREVENÇÃO PARA DISTÚRBIOS ADQUIRIDOS DA HEMOSTASIA." In II Congresso Brasileiro de Hematologia Clínico-laboratorial On-line. Revista Multidisciplinar em Saúde, 2022. http://dx.doi.org/10.51161/hematoclil/40.

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Introdução: A hemostasia baseia-se no mecanismo de bloqueio de uma ruptura vascular, o que garante a integridade desses vasos por meio dos fatores da coagulação sanguínea. Algumas alterações nos fatores de coagulação podem acarretar distúrbios que comprometam o processo de coagulação e consequentemente a hemostasia vascular, como a deficiência da vitamina K a qual é fundamental para a síntese dos carreadores da coagulação. A sua significância no que concerne a clínica médica provém das anormalidades hemostáticas desencadeadas pelos distúrbios adquiridos provenientes da carência da vitamina K. Objetivos: Analisar como a deficiência da vitamina K está associada aos distúrbios adquiridos de coagulação no processo hemostático atrelado aos fatores de risco, como má absorção intestinal de vitaminas, uso contínuo de antibióticos orais e quadros ictéricos graves, averiguando os distúrbios causados na coagulação sanguínea que interferem na qualidade de vida do indivíduo. Material e métodos: O estudo efetuado foi de caráter analítico propiciando a elaboração de avaliações comparativas dos estudos bibliográficos encontrados na base de dados SciELO, utilizando os seguintes descritores: vitamina K, hemostasia, prática clínica, distúrbios de coagulação. Resultados: Foi apurado que a vitamina K é um cofator constituinte da formação do ácido gama carboxiglutâmico, atuando como precursor da coagulação sanguínea. Logo, uma má absorção intestinal da vitamina, ocasionada pelas mais diversas patologias - síndrome de má absorção intestinal, obstrução biliar, fibrose cística, dentre outros - ou ainda, uma ingestão diária inferior a 1mg/kg resultam em um quadro de hipoprotrombinemia que aumentam o risco de hemorragias. Ademais, algumas classes de antibióticos, a exemplo das cefalosporinas, tem habilidade de impedir a epoxi-redutase de vitamina K, inibindo seu ciclo. Sobre pacientes com icterícia obstrutiva que tiveram o comprometimento da hemostasia, os estudos demonstraram uma concomitância entre a faixa etária dos pacientes e a atividade dos fatores de coagulação vitamina K dependentes, além de uma diminuição significativa na atividade dos mesmos. Conclusão: O conhecimento específico acerca da hemostasia atrelado a deficiência da vitamina K e seus fatores de risco possibilitará um maior controle das alterações adquiridas sobre a coagulação através de medidas profiláticas precoces, bem como proporcionará estudos direcionados facilitando os diagnósticos e seus respectivos tratamentos.
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