Dissertations / Theses on the topic 'Helma'
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Bleses, Helma [Verfasser], Friedhelm [Gutachter] Dietze, J. [Gutachter] Schulz, and Rüdiger H. [Gutachter] Jung. "Patientenorientierung als Qualitätsmerkmal / Helma Bleses ; Gutachter: Friedhelm Dietze, J. Schulz, Rüdiger H. Jung." Berlin : Humboldt-Universität zu Berlin, 2005. http://d-nb.info/1207645214/34.
Full textBleses, Helma M. [Verfasser], Friedhelm [Gutachter] Dietze, J. [Gutachter] Schulz, and Rüdiger H. [Gutachter] Jung. "Patientenorientierung als Qualitätsmerkmal / Helma Bleses ; Gutachter: Friedhelm Dietze, J. Schulz, Rüdiger H. Jung." Berlin : Humboldt-Universität zu Berlin, 2005. http://d-nb.info/1207645214/34.
Full textFerla, Joselia Jantsch. "HELMA BERCH E O ENSINO DE MÚSICA NO CONTEXTO DA IMIGRAÇÃO ALEMÃ CATÓLICA DO VALE DO TAQUARI." Universidade Federal de Santa Maria, 2009. http://repositorio.ufsm.br/handle/1/6895.
Full textA presente dissertação, vinculada à linha de pesquisa Educação e Artes - LP4, do Programa de Pós Graduação em Educação, da Universidade Federal de Santa Maria, buscou analisar a trajetória da professora Helma Bersch, frente ao ensino de música no contexto da imigração alemã católica do sul do país, a qual atuou profissionalmente no período de 1932 a 1981, na Sociedade Escolar Dona Rita, localizada em Arroio do Meio, no Vale do Taquari, região noroeste do estado do Rio Grande do Sul. Buscou-se ainda investigar o processo de formação musical da professora; conhecer as práticas musicais desenvolvidas em sala de aula; assim como examinar a repercussão do trabalho de Helma para a comunidade de Dona Rita. Este estudo, de natureza qualitativa, utilizou os recursos metodológicos da história oral, alicerçando-se em estudos de Bourdieu (2006), Levi (2006) e Schmidt (2000), em uma perspectiva na qual a história de uma vida é tomada como via de acesso para a articulação de questões ou contextos mais amplos. Foram utilizados ainda como referenciais os trabalhos de Kreutz (2004, 2000, 1999, 1994), Garbosa (2006, 2004, 2003) e Bersch (2006). Ao analisar a trajetória da professora Helma Bersch, foi possível registrar a história de uma professora que fez de sua vida uma parte da história do ensino de música nas escolas Sul do Brasil, trazendo para a discussão especificidades em relação ao modo de conceber tal ensino, no período e contexto analisados. Foi possível ainda, refletir sobre a formação da professora e a formação ofertada aos alunos, as especificidades das práticas pedagógicas, os materiais didáticos utilizados, os instrumentos musicais presentes no contexto, assim como as repercussões do trabalho desenvolvido pela professora Helma, na Sociedade Escolar Dona Rita. Através deste estudo, foi possível verificar as contribuições de Helma Bersch para o desenvolvimento educacional, cultural e econômico do Vale, no qual a música exerceu importante papel de integração, identificação e difusão de elementos culturais e religiosos, sendo a escola o local escolhido para se atingir e manter o status quo do momento.
Fehn, Anne-Maria [Verfasser], Anne [Gutachter] Storch, Helma [Gutachter] Pasch, and Thomas [Gutachter] Widlok. "A Grammar of Ts'ixa (Kalahari Khoe) / Anne-Maria Fehn ; Gutachter: Anne Storch, Helma Pasch, Thomas Widlok." Köln : Universitäts- und Stadtbibliothek Köln, 2014. http://d-nb.info/1121174531/34.
Full textPopp, Marion Claudia Helma [Verfasser], and Karsten [Akademischer Betreuer] Hadwich. "Führung im Dienstleistungskontext : eine Betrachtung aus Unternehmens-, Mitarbeiter- und Kundenperspektive / Marion Claudia Helma Popp ; Betreuer: Karsten Hadwich." Hohenheim : Kommunikations-, Informations- und Medienzentrum der Universität Hohenheim, 2018. http://d-nb.info/1169210783/34.
Full textKröger, Oliver [Verfasser], Gerrit [Gutachter] Dimmendaal, Helma [Gutachter] Pasch, and Anne [Gutachter] Storch. "Personenreferenz und Textorganisation in Erzählungen des mosambikanischen Ngoni / Oliver Kröger ; Gutachter: Gerrit Dimmendaal, Helma Pasch, Anne Storch." Köln : Universitäts- und Stadtbibliothek Köln, 2016. http://d-nb.info/1117134857/34.
Full textKröger, Oliver [Verfasser], Gerrit Gutachter] Dimmendaal, Helma [Gutachter] Pasch, and Anne [Gutachter] [Storch. "Personenreferenz und Textorganisation in Erzählungen des mosambikanischen Ngoni / Oliver Kröger ; Gutachter: Gerrit Dimmendaal, Helma Pasch, Anne Storch." Köln : Universitäts- und Stadtbibliothek Köln, 2016. http://nbn-resolving.de/urn:nbn:de:hbz:38-69683.
Full textLandi, Germain [Verfasser], Helma [Gutachter] Pasch, Reinhold [Gutachter] Greisbach, Gerrit [Gutachter] Dimmendaal, and Anne [Gutachter] Storch. "Phonologie et morphophonologie de la langue Zandé / Germain Landi ; Gutachter: Helma Pasch, Reinhold Greisbach, Gerrit Dimmendaal, Anne Storch." Köln : Universitäts- und Stadtbibliothek Köln, 2019. http://d-nb.info/1215293720/34.
Full textRostock, Petra Verfasser], Helma [Akademischer Betreuer] [Lutz, and Birgit [Akademischer Betreuer] Sauer. "Jenseits von "Identität"? : zu den Un/Möglichkeiten nicht-identitärer Strategien politischen Handelns / Petra Rostock. Gutachter: Helma Lutz ; Birgit Sauer." Frankfurt am Main : Univ.-Bibliothek Frankfurt am Main, 2014. http://d-nb.info/1063632218/34.
Full textRostock, Petra [Verfasser], Helma [Akademischer Betreuer] Lutz, and Birgit [Akademischer Betreuer] Sauer. "Jenseits von "Identität"? : zu den Un/Möglichkeiten nicht-identitärer Strategien politischen Handelns / Petra Rostock. Gutachter: Helma Lutz ; Birgit Sauer." Frankfurt am Main : Univ.-Bibliothek Frankfurt am Main, 2014. http://d-nb.info/1063632218/34.
Full textVilímovský, Daniel. "Aplikace moderních technologií pro návrh a výrobu prototypu lyžařské helmy." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2021. http://www.nusl.cz/ntk/nusl-443216.
Full textKane, Fatou Cisse [Verfasser], Anne [Gutachter] Storch, Gerrit [Gutachter] Dimmendaal, Richard [Gutachter] Bußmann, Birgit [Gutachter] Hellwig, Helma [Gutachter] Pasch, and Anji [Gutachter] Mietzner. "Description générale de l'oniyan / Fatou Cisse Kane ; Gutachter: Anne Storch, Gerrit Dimmendaal, Richard Bußmann, Birgit Hellwig, Helma Pasch, Anji Mietzner." Köln : Universitäts- und Stadtbibliothek Köln, 2019. http://d-nb.info/1205068422/34.
Full textFreitag, Helma [Verfasser]. "Inhibition der PI3K/AKT/mTOR-Signaltransduktion: innovative Therapieoptionen für neuroendokrine Tumore auf Basis eines tieferen Verständnisses intrazellulärer Prozesse in NEN / Helma Freitag." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2018. http://d-nb.info/1160515352/34.
Full textRothkirch, Sandra Petra Helma [Verfasser], Carsten [Akademischer Betreuer] Schmidt-Weber, Carsten [Gutachter] Schmidt-Weber, and Florian [Gutachter] Bassermann. "Durchflusszytometrische Charakterisierung von T- und B-Zellsubpopulationen im Sputum und peripheren Blut / Sandra Petra Helma Rothkirch ; Gutachter: Carsten Schmidt-Weber, Florian Bassermann ; Betreuer: Carsten Schmidt-Weber." München : Universitätsbibliothek der TU München, 2018. http://d-nb.info/1188408607/34.
Full textKleinhorst, Helma [Verfasser], Katrin [Gutachter] Sommer, and Nils [Gutachter] Metzler-Nolte. "KEMIEplus : Konzeption und Wirksamkeit von Experimentiereinheiten mit dem Schwerpunkt "naturwissenschaftliche Denk- und Arbeitsweisen" / Helma Kleinhorst ; Gutachter: Katrin Sommer, Nils Metzler-Nolte ; Fakultät für Chemie und Biochemie." Bochum : Ruhr-Universität Bochum, 2013. http://d-nb.info/1228624003/34.
Full textStef, Cristina. "Hemma/Home." Thesis, Konstfack, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:konstfack:diva-3021.
Full textHultin, Kajsa, and Lina Millevik. "Hemma är jag fortsatt trött, men jag är hemma : Patienters upplevelser av att vårdas hemma i livets slut." Thesis, Mälardalens högskola, Akademin för hälsa, vård och välfärd, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:mdh:diva-38761.
Full textSpohn, Anna Margareta. "Helga Philipp eine Monografie." Wien Praesens-Verl, 2006. http://deposit.d-nb.de/cgi-bin/dokserv?id=2862182&prov=M&dok_var=1&dok_ext=htm.
Full textElfmark, Zdeněk. "Antény integrované do helmy." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2013. http://www.nusl.cz/ntk/nusl-220256.
Full textBártová, Jana. "Návrh zkapalňovacího cyklu Helia." Master's thesis, Vysoké učení technické v Brně. Fakulta strojního inženýrství, 2020. http://www.nusl.cz/ntk/nusl-417538.
Full textHelmetag, Arnd. "Improvement of perception and cognition in synthetic spatial environments." [S.l.] : [s.n.], 2000. http://elib.tu-darmstadt.de/diss/000130/Helm2.pdf.
Full textBlomberg, Sara. "Hela staden ska vara med! : Hela staden ska vara med!" Thesis, Örebro universitet, Institutionen för humaniora, utbildnings- och samhällsvetenskap, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:oru:diva-37078.
Full textNorstedt, Karin. "Hela barnet hela dagen : Om fritidshemspersonalens tillgång till specialpedagogiskt stöd." Thesis, Malmö universitet, Malmö högskola, Institutionen för skolutveckling och ledarskap (SOL), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-40084.
Full textYtterberg, Adam. "Partikel hela vägen." Thesis, Konstfack, Institutionen för Konst (K), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:konstfack:diva-6074.
Full textIngelfinger, Helmar [Verfasser]. "Arbeitsplatzgestaltung durch Betriebsnormen. / Helmar Ingelfinger." Berlin : Duncker & Humblot, 2021. http://d-nb.info/1238267866/34.
Full textDugonic, Vesna. "TAKK för hela förskolan." Thesis, Malmö universitet, Fakulteten för lärande och samhälle (LS), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-33437.
Full textBrodmann, Ulrich. "Wertübertragung im Musikunterricht des 19. Jahrhunderts dargestellt am Beispiel der Musikdidaktik von Johann Helm /." [S.l. : s.n.], 2002. http://deposit.ddb.de/cgi-bin/dokserv?idn=965607682.
Full textHornung, Helga [Verfasser]. "Örtliche Finanzkontrolle als Innovationsfaktor / Helga Hornung." Kassel : Kassel University Press, 2014. http://d-nb.info/1065323069/34.
Full textRaible, Helga [Verfasser]. "Trypsinogenaktivationspeptid bei akuter Pankreatitis / Helga Raible." Ulm : Universität Ulm. Medizinische Fakultät, 2002. http://d-nb.info/1015323847/34.
Full textThorsell, Heléne. "Patienter som lämnades hemma efter ambulanslarm." Thesis, Högskolan i Gävle, Akademin för hälsa och arbetsliv, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-17304.
Full textHillring, Björn. ""De ser hela barnet, hela dagen" : Fritidspedagogers uppdrag och ansvarsområden sett med rektorers glasögon." Thesis, Umeå universitet, Institutionen för tillämpad utbildningsvetenskap, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-121124.
Full textTabet-Helal, Sana Zouleykha. "Impacts moléculaire et cellulaire de mutations de la partie N-terminale de la stathmine." Thesis, Evry-Val d'Essonne, 2014. http://www.theses.fr/2014EVRY0010/document.
Full textMicrotubules (MTs) are major constituents of the cytoskeleton and are involved in many cellular processes such as the determination of cell architecture, the formation of the mitotic spindle and intracellular trafficking. These tubular structures, composed by tubulin α/β heterodimers assemble and disassemble with a finely regulated dynamics.Stathmin is a cytosolic phosphoprotein that sequesters tubulin in a non polymerizable complex consisting of two tubulin heterodimers per stathmin molecule (T2S complex).The other stathmin family proteins (SCG10, SCLIP, RB3 and its two splice variants RB3 'and RB3 ") can also bind two tubulin heterodimers through their SLD (Stathmin Like Domain), but the different tubulin/SLD complexes display varying stabilities.Based on these observations, current works showed that one chimera protein consisting of the N-terminal domain of stathmin (NS) and of the C-terminal domain of RB3 (CR) forms a T2-SLD complex remarkably stable with tubulin (NS-CR chimera). Molecular simulation experiments in silico suggest that we can increase the affinity of the NS-CR chimera by introducing mutations in the NS subdomain (Jourdain et al., 2004).In parallel to this work, Clement and colleagues found that short peptides derived from the N-terminal region of SLD alone can inhibit tubulin polymerization. Among the N-terminal part of SLD, the most effective peptide is the peptide I19L (IQVKELEKRASGQAFELIL) derived from stathmin. It corresponds to region folded into a "β-hairpin" structure observed in the T2S crystals (Clement et al., 2005). To increase the efficiency of this interaction, different mutations were introduced at the level of the I19L peptide from the stathmin N-terminal domain and tested in vitro. The results showed that the peptides I19L-K4R and I19L-K4R-A10R are the most effective to in inhibit the assembly of MTs.In this work, we introduce these mutations in the N-terminal domains of stathmin and in the NS-CR chimera with the aim of analyzing their efficiencies on MTs disassembly in cancer cell cultures like HeLa, and the impact of the mutation on MTs dynamic and cell cycle.Results from overexpression experiments of WT and stathmin mutant 2 containing the double mutation (K9R-A15R similar to the mutations K4R-A10R for the I19L peptide), suggest that this mutant significantly induces depolymerization of mitotic MTs. In its less phosphorylated state on serine 16; this mutation also reduces MTs dynamics and induces cytotoxicity.We thus suggest that we can ameliorate the binding and efficiency of the N-terminal stathmin part by including this double mutation. This variation has an impact in vitro and in some cellular aspects such as cell proliferation and MTs dynamics. These findings may lead to a targeted therapy for this type of cancer
Bergh, Nestlog Ewa. "Hela svenskan : Integrering inom svenskämnet." Thesis, Växjö University, School of Humanities, 2005. http://urn.kb.se/resolve?urn=urn:nbn:se:vxu:diva-1794.
Full textSyftet med denna uppsats är att undersöka en funktionell svenskundervisning där undervisning om språkliga strukturer integreras i undervisningen kring eget skrivande och analys av egna och andras texter. Fokus ligger på undervisningens relation till kontextuella aspekter av verksamheten, såsom sammanhang som har att göra med praxis i klassrummet, den enskilda skolan och yttre ramar på ett samhälleligt plan. Centrala begrepp är dialogicitet, processer, stödstrukturer, undervisning rörande språkliga strukturer, integrering, erfarenhetspedagogisk ämnessyn och text som socialt beteende. Såväl min analysapparat som den studerade undervisningen har inspirerats av ett sociokulturellt perspektiv på lärande, särskilt nydialogiska och genrepedagogiska teorier.
Studien följer fyra undervisningsförlopp i grundskolans senare år och i gymnasieskolan genom observationer, samtal i fokusgrupper samt intervjuer med lärare och elever.
Resultatet visar att den genomförda undervisningen värderas högt av lärare och elever, och lärarna menar att alla kategorier av elever tjänar på denna typ av integrerad undervisning. Den upplevs som effektiv och engagerande. Vad gäller de centrala begreppen, som nämnts ovan, kan man konstatera att det verkar ha funnits en strävan att implementera dessa i den studerade undervisningen, vilket också har skett i olika grad. En ytlig iscensättning av dessa begrepp i praktiken innebär dock knappast en undervisning som kan anses gestalta forskares teorier kring dessa begrepp. Ett flertal kontextuella aspekter på olika nivåer har identifierats som betydelsefulla i sammanhanget, som exempelvis läromedlens roll; lärarnas kunskaper och syn på lärande, på svenskämnet och på texter; lärarnas behov av forum för diskussioner och reflektion kring svenskundervisningen.
Lindskog, Ann-Sofie, and Ida Ringdahl. "Ovisshet upptar människans hela sfär." Thesis, Kristianstad University College, School of Health and Society, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:hkr:diva-5097.
Full textBakgrund: Att inte veta hur saker och ting förhåller sig, är att sväva i ovisshet. Att leva i ovisshet och att inte veta hur ens framtid kommer att bli kan skapa funderingar som kan leda till olika reaktioner. Sådana funderingar och reaktioner blir ofta synliga i berättelser om det inträffade. En berättelse är en skildring av ett händelseförlopp muntligt eller skriftligt av verkliga eller påhittade händelser. Genom berättandet fångas helheten upp och återskapar upplevelser och känslor. Syfte: Syftet med studien var att få en ökad förståelse för fenomenet ovisshet. Metod: Studien genomfördes som en empirisk studie där studenters livsvärldsberättelser om fenomenet ovisshet utgjorde grunden för resultatet. Materialet har analyserats med kvalitativ innehållsanalys. Resultatet: Resultatet presenterades utefter tre frågor: 1 Vad innebär ovisshet? Tankar om framtiden och att inte ha makt att kunna påverka, 2 När uppkommer ovisshet? När det vardagliga bryts och 3 Vad gör ovisshet med människan? Känslor här och nu, tankar som svävar iväg. Diskussion: En ökad förståelse för vad ovisshet är underlättar för sjuksköterskan i hennes arbete att vårda och förstå den enskilde patientens livsvärld.
Bootman, Martin D. "Calcium spiking in HeLa cells." Thesis, University of Cambridge, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.281898.
Full textMalmborg, Nordgren Camilla. "Viktigt på riktigt, hela dagen." Thesis, Malmö universitet, Fakulteten för lärande och samhälle (LS), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-33712.
Full textUriondo, Boudri Heydy Wendy. "Estudios sobre la exportación de la proteína quinasa dependiente de cAMP en células humanas en cultivo." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2007. https://hdl.handle.net/20.500.12672/2515.
Full textTesis
Mittendorff, Martin [Verfasser], Manfred [Akademischer Betreuer] Helm, and Joachim [Akademischer Betreuer] Ohser. "Carrier Relaxation Dynamics in Graphene / Martin Mittendorff. Gutachter: Manfred Helm ; Joachim Ohser. Betreuer: Manfred Helm." Dresden : Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2015. http://d-nb.info/106909286X/34.
Full textMittendorff, Martin [Verfasser], Manfred Akademischer Betreuer] Helm, and Joachim [Akademischer Betreuer] [Ohser. "Carrier Relaxation Dynamics in Graphene / Martin Mittendorff. Gutachter: Manfred Helm ; Joachim Ohser. Betreuer: Manfred Helm." Dresden : Saechsische Landesbibliothek- Staats- und Universitaetsbibliothek Dresden, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:14-qucosa-159690.
Full textPaulsson, Kajsa. "Hemma Hos Oss : Bostäder för dagens familjer." Thesis, KTH, Arkitektur, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-35092.
Full textNilsson, Hanna. "”Det är lite som att vara hemma”." Thesis, Halmstad University, School of Social and Health Sciences (HOS), 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:hh:diva-2153.
Full textMina tankar inför valet av undersökning var att det finns ett stort intresse för organisation och
kön. Äldreomsorgen blev ett självklart val av arena för utförande av undersökning då det är en
verksamhet med stor könsobalans. I takt med samhällets utveckling vad gäller
jämställdhetstänkande, är det befogat anser jag att ställa sig frågan hur det kommer sig att
äldreomsorgen utvecklas så långsamt på detta område. Därför är min fråga ”Hur skapas och
återskapas könsobalansen på äldreboendet?” Syftet med arbetet är att ge en bild av hur
kvinnor och äldreomsorgen tillsammans skapar och återskapar könsobalansen. Syftet är
nedbrutit i två frågeställningar:
1) Hur kan man förklara könsobalansen på ett äldreboende?
2) Spelar kvinnors erfarenheter roll i skapandet av könsobalansen på äldreboendet?
Samtal med undersköterskor på ett äldreboende har lyft fram erfarenheter från såväl privatliv
som arbetsliv. En intervju med enhetschefen gav mig en beskrivning av boendet och en
observation av äldreboendet visade hur det dagliga arbetet kan se ut. Mitt material har
analyserats med hjälp av två teorier. Den ena teorin förklarar könsobalansen genom en
utgångspunkt i organisationen medan den andra ser mer till individen.
De kvinnliga undersköterskornas gemensamma erfarenheter kunde beskrivas genom den
”kollektiv kulturen”(Lindgren, 1992). Resultatet från undersökningen visar bland annat att
kvinnorna menar att alla är bra på olika saker och ser på så sätt arbetsdelningen som
komplementär. Detta är en del av könsmärkningsprocessen (Acker, 1990 ref i:Westberg
1996). Fler män hade underlättat de tunga lyften och de hade tillfört rakhet till det ”tjafsiga”
arbetsklimatet.
Det finns en önskan om fler män i äldreomsorgen, men hur man verkligen arbetar konkret
med rekrytering av fler män är en fråga som uppkommit i samband med denna önskan.
Andersson, Ellen. "Att känna sig hemma : - Platser och identitet." Thesis, Uppsala universitet, Kulturgeografiska institutionen, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-275850.
Full textBelokozovska, Veronica, and Emina Begic. "JAG HÖR INTE HEMMA BLAND VANLIGA “SVENSSONS”." Thesis, Malmö universitet, Fakulteten för hälsa och samhälle (HS), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-25814.
Full textThe purpose of the essay is to investigate the professional's view of how reintegration looks for people who have committed criminal acts and who have been imprisoned for these actions. This essay includes an analysis and a problematization of which possibilities and obstacles people who have been in prison can meet during the reintegration. To answer the main question was the research area based on the following questions: How does the reintegration into society look for people who have been in prison? Which opportunities and obstacles can people meet after prison? The empirical material of the study is based on six qualitative semi-structured interviews. The analysis contains an interweaving of the qualitative interviews, previous research and different theories. The result shows that the conditions for reintegration can look different from individual to individual. Frivården (The Swedish Prison and Probation Service) and Krami (a function that helps former criminals back to the labor market) works to encourage the conditions for reintegration. Besides to the professional role and their daily work, there are several individual factors: work and housing, motivation and will, social network, and the societal view that exists towards people who have been in prison. These factors are important and can either be of benefit or disadvantage to the person's reintegration into society. However, these factors do not need to be seen as turning points in the person's life but as a helping hand in order not to fall back into crime. The conclusion is that reintegration is about an interweaving of different factors in the person's life, where the interaction between different instances, already at an early stage, is of importance for encouraging people's opportunities in society to be able to live a legal life.
Tsakiridis, George. "God and time a comparative study of Augustine and Paul Helm /." Online full text .pdf document, available to Fuller patrons only, 2002. http://www.tren.com.
Full textSouza, Aryane Tofanello de [UNESP]. "Síntese e caracterização de nanopartículas magnéticas de óxido de ferro para aplicações biomédicas – um estudo citotóxico em linhagem celular de carcinoma cervical humano (células HeLa)." Universidade Estadual Paulista (UNESP), 2011. http://hdl.handle.net/11449/92023.
Full textConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Nanopartículas magnéticas (NPMs) têm sido alvo de inúmeras investigações por seu grande potencial de aplicação nos mais diferentes campos tecnológicos. Dentre tantos, elas destacam-se na área biomédica, seja no diagnóstico ou tratamento de diversas doenças. Neste trabalho foram sintetizadas nanopartículas magnéticas (NPMs) de óxido de ferro (magnetita) pelo método de coprecipitação de íons Fe2+ e Fe3+ em meio alcalino. O objetivo central foi estudar as características morfológicas, estruturais, magnéticas e o comportamento biológico desses compostos em células cancerígenas, visando futuras aplicações biomédicas. Inicialmente as nanopartículas magnéticas foram avaliadas em função dos parâmetros físico-químicos que influenciam diretamente as características finais do produto (pH, molaridade, temperatura e tipo de base) para se observar as melhores condições de síntese e a influência de cada um nas características do produto. As nanopartículas foram caracterizadas por difratometria de raios-X, microscopia eletrônica de varredura, potencial zeta e magnetometria. Desse primeiro estudo concluiu-se que a coprecipitação produz partículas com polidispersão de tamanhos alta e que os parâmetros de síntese influenciam drasticamente as propriedades dos materiais, no entanto, todas as amostras exibiam características magnéticas. Depois de estabelecida esta etapa, as NPMs foram submetidas à transfecção em cultura celular de carcinoma cervical humano (células HeLa) e a testes biológicos como coloração com Azul da Prússia e hematoxilina-eosina, ensaio de MTT e ensaio de apoptose para averiguação da citotoxidade. A principal observação vinda desses resultados foi que as nanopartículas magnéticas sintetizadas, salvo algumas adaptações de síntese...
Magnetic nanoparticles (MNPs) have been the subject of numerous investigations because of its great potential application in many different fields of technology. Among many, they stand out in the biomedical area, either in diagnosis or treatment of various diseases. In this work were synthesized magnetic nanoparticles (MNPs) of iron oxide (magnetite) by the coprecipitation method of Fe2+ and Fe3+ in an alkaline medium. The main objective was to study the morphological, structural, magnetic and biological behavior of these compounds in cancer cells, in order to future biomedical applications. Initially the magnetic nanoparticles were evaluated against the physical and chemical parameters that directly influence the final characteristics of product (pH, molarity, temperature and type of base) to observe the best synthesis conditions and influence of each characteristics. The nanoparticles were characterized by X-ray diffraction, sccaning electron microscopy, zeta potential and magnetometry. In this first study showed that coprecipitation produces particles with high polydispersity of sizes and that the synthesis parameters dramatically influence the properties of materials, however all samples exhibited magnetic characteristics. After you make this step, the MNP were subjected to transfection in cell culture of human cervical carcinoma (HeLa) and biological tests such as staining with Prussian blue and hematoxylin-eosin, MTT assay and apoptosis assay to investigate cytotoxicity. The main observation was that these results coming magnetic nanoparticles synthesized, except for some adjustments in short, constitute a class of nanocomposites with enormous potential for therapeutic and / or diagnosis. The work brings together information ranging from the synthesis of nanoparticles to their behavior inside the cells, emphasizing the best conditions for each procedure
Oliveira, Ruth Medeiros de. "Avalia??o das atividades antioxidante, anticoagulante e antiproliferativa de extratos aquosos de marsdenia megalantha." Universidade Federal do Rio Grande do Norte, 2011. http://repositorio.ufrn.br:8080/jspui/handle/123456789/12576.
Full textCoordena??o de Aperfei?oamento de Pessoal de N?vel Superior
The species of the genus Marsdenia, Apocynaceae, are widely used in folk medicine of several countries. In Brazil is found several species belonging to this genus. The in vitro antioxidant, anticoagulant and antiproliferative activities were evaluated to aqueous extracts of stalk, leaf and root of Marsdenia megalantha. In the total antioxidant capacity assay (expressed as ascorbic acid equivalents) the stalk extract showed 76.0 mg/g, while leaf and root extracts 141.3 mg/g and 57.0 mg/g, respectively. The stalk and leaf extracts showed chelating activity around 40% at 1.5 mg/mL, while root extract, at the same concentration showed, 17%. Only the leaf extract showed a significant ability in superoxide scavenging (80% at 0.8 mg/mL). Any extract was able in scavenge hydroxyl, as well anticoagulant activity. The antiproliferative activity of the extracts was evaluated against HeLa tumor cell line. The extracts inhibited in a dose-dependent manner the cell growth. However, the leaf extract showed 80% of inhibition at 1.0 mg/mL, while stalk and root extracts inhibited 63% and 30%, respectively. To assess the mechanism of cell death caused by the leaf extract in HeLa, was performed flow cytometry and western blot. The results show that leaf extract induces cell death by apoptosis through an activation caspase-independent pathway. These data indicate that stalk and leaf extracts obtained have potential to be used as antioxidants and anticancer drugs
As esp?cies do g?nero Marsdenia, Apocynaceae, s?o bastante utilizadas na medicina popular de v?rios pa?ses. No Brasil s?o encontradas v?rias esp?cies pertencentes a esse g?nero. As atividades antioxidante, anticoagulante e antiproliferativa foram avaliadas para os extratos de caule, folha e raiz de Marsdenia megalantha. Na capacidade antioxidante total (expressa como equivalente de ?cido asc?rbico), o extrato do caule apresentou 76,0 mg/g, enquanto os extratos da folha e raiz apresentaram, respectivamente, 14,3 mg/g e 57,0 mg/g. Os extratos do caule e da folha mostraram habilidade quelante em torno de 40% na concentra??o de 1,5 mg/mL, enquanto o extrato da raiz, na mesma concentra??o, apresentou 17%. Apenas o extrato da folha apresentou uma capacidade significante em sequestrar radicais super?xidos (80% em 0,8 mg/mL). Nenhum extrato mostrou capacidade em seq?estrar radicais hidroxila, bem como atividade anticoagulante. A atividade antiproliferativa dos extratos foi avaliada contra a linhagem tumoral HeLa. Os extratos inibiram, de forma dose-dependente, o crescimento celular. Entretanto, o extrato da folha foi capaz de inibir em 80% a prolifera??o celular na concentra??o de 1,0 mg/mL, enquanto os extratos de caule e raiz inibiram 63% e 30%, respectivamente. Para avaliar o mecanismo de morte celular causada pelo extrato da folha nas c?lulas HeLa, foi realizada citometria de fluxo e western blot. Os resultados mostraram que o extrato da folha induz morte celular por apoptose atrav?s de uma via de ativa??o independente de caspase. Estes resultados indicam que os extratos de caule e folha obtidos t?m potencial para serem futuramente utilizados como f?rmacos antioxidantes e antic?ncer
Souza, Aryane Tofanello de. "Síntese e caracterização de nanopartículas magnéticas de óxido de ferro para aplicações biomédicas - um estudo citotóxico em linhagem celular de carcinoma cervical humano (células HeLa) /." São José do Rio Preto : [s.n.], 2011. http://hdl.handle.net/11449/92023.
Full textBanca: Paula Rahal
Banca: Maria Cristina Nonato Costa
Resumo: Nanopartículas magnéticas (NPMs) têm sido alvo de inúmeras investigações por seu grande potencial de aplicação nos mais diferentes campos tecnológicos. Dentre tantos, elas destacam-se na área biomédica, seja no diagnóstico ou tratamento de diversas doenças. Neste trabalho foram sintetizadas nanopartículas magnéticas (NPMs) de óxido de ferro (magnetita) pelo método de coprecipitação de íons Fe2+ e Fe3+ em meio alcalino. O objetivo central foi estudar as características morfológicas, estruturais, magnéticas e o comportamento biológico desses compostos em células cancerígenas, visando futuras aplicações biomédicas. Inicialmente as nanopartículas magnéticas foram avaliadas em função dos parâmetros físico-químicos que influenciam diretamente as características finais do produto (pH, molaridade, temperatura e tipo de base) para se observar as melhores condições de síntese e a influência de cada um nas características do produto. As nanopartículas foram caracterizadas por difratometria de raios-X, microscopia eletrônica de varredura, potencial zeta e magnetometria. Desse primeiro estudo concluiu-se que a coprecipitação produz partículas com polidispersão de tamanhos alta e que os parâmetros de síntese influenciam drasticamente as propriedades dos materiais, no entanto, todas as amostras exibiam características magnéticas. Depois de estabelecida esta etapa, as NPMs foram submetidas à transfecção em cultura celular de carcinoma cervical humano (células HeLa) e a testes biológicos como coloração com Azul da Prússia e hematoxilina-eosina, ensaio de MTT e ensaio de apoptose para averiguação da citotoxidade. A principal observação vinda desses resultados foi que as nanopartículas magnéticas sintetizadas, salvo algumas adaptações de síntese... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: Magnetic nanoparticles (MNPs) have been the subject of numerous investigations because of its great potential application in many different fields of technology. Among many, they stand out in the biomedical area, either in diagnosis or treatment of various diseases. In this work were synthesized magnetic nanoparticles (MNPs) of iron oxide (magnetite) by the coprecipitation method of Fe2+ and Fe3+ in an alkaline medium. The main objective was to study the morphological, structural, magnetic and biological behavior of these compounds in cancer cells, in order to future biomedical applications. Initially the magnetic nanoparticles were evaluated against the physical and chemical parameters that directly influence the final characteristics of product (pH, molarity, temperature and type of base) to observe the best synthesis conditions and influence of each characteristics. The nanoparticles were characterized by X-ray diffraction, sccaning electron microscopy, zeta potential and magnetometry. In this first study showed that coprecipitation produces particles with high polydispersity of sizes and that the synthesis parameters dramatically influence the properties of materials, however all samples exhibited magnetic characteristics. After you make this step, the MNP were subjected to transfection in cell culture of human cervical carcinoma (HeLa) and biological tests such as staining with Prussian blue and hematoxylin-eosin, MTT assay and apoptosis assay to investigate cytotoxicity. The main observation was that these results coming magnetic nanoparticles synthesized, except for some adjustments in short, constitute a class of nanocomposites with enormous potential for therapeutic and / or diagnosis. The work brings together information ranging from the synthesis of nanoparticles to their behavior inside the cells, emphasizing the best conditions for each procedure
Mestre
Flynn, Patrick G. "Activation of Non-Muscle Myosin IIB Helps Mediate TNF-Alpha Cell Death Signaling." Scholarly Repository, 2010. http://scholarlyrepository.miami.edu/oa_dissertations/369.
Full textBonnard, Erika. "Uppochnervända roller hemma hos Martina : En undersökning av den självförringande humorns subversiva kraft i Martina Haags Hemma hos Martina." Thesis, Södertörn University College, School of Gender, Culture and History, 2006. http://urn.kb.se/resolve?urn=urn:nbn:se:sh:diva-482.
Full textMartina Haag’s method of self-mockery used in her chronicles is characterized by her wish to live up to various ideals. This essay brings out the subversive power of self-deprecatory hu-mor expressed in her book Hemma hos Martina. The author’s strategies and kinds of humor are being studied, leading up to what this humor accomplishes. General theories on humor, by Mary Ann Rishel, Maria Ohlsson, Henri Bergson, Joannne R. Gilbert and Simon Critchley are being applied to find the essence of her craftsmanship in writing comedy. The analysis also goes more closely into the style and language, to give a deeper understanding of how she creates jokes, and also how she relates to her ideals through language. The main thrust of the analysis, though, builds on theories on self-deprecatory humor. Haag is included into Joanne R. Gilbert’s theory on self-deprecation and The Whiner within the field of stand-up comedy.
Some American feminist critics have rejected self-deprecatory humor as being anti-feminist, stating that women applying this particular kind of humor merely reinforce stereoty-pes, and put themselves down. This paper objects to those critics, leaning on Haag’s book. I wish to show that Haag is not demeaning towards herself, but towards the cultural norms and expectations in our present society. In this context, I show how Haag manages to demystify and criticize ideal representations of women, by lampooning them and revolting against them. In this way, her book turns into a satirical critique of cultural values. My essay illustrates how Haag objectifies herself, making regular use of stereotypes. This is necessary, since these two elements are essential to most humor. Haag confirms stereotypes to make people laugh. This laughter brings about awareness in the reader, making Haag’s work a social critique of current values and norms concerning women.
Schaller, Kerstin [Verfasser], Helga [Akademischer Betreuer] Bernhard, and Christian [Akademischer Betreuer] Peschel. "Generierung zytotoxischer T-Zellen gegen das tumorassoziierte Antigen HER3 / Kerstin Schaller. Gutachter: Helga Bernhard ; Christian Peschel. Betreuer: Helga Bernhard." München : Universitätsbibliothek der TU München, 2012. http://d-nb.info/1031513787/34.
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