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1

Kittisupamongkol, W. "Heerfordt syndrome." QJM 102, no. 2 (2008): 149. http://dx.doi.org/10.1093/qjmed/hcn156.

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2

Larsen, Victor. "CHRISTIAN HEERFORDT." Acta Ophthalmologica 31, no. 5 (2009): 397–99. http://dx.doi.org/10.1111/j.1755-3768.1953.tb07658.x.

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3

Füeßl, H. S. "Heerfordt-Syndrom." MMW - Fortschritte der Medizin 155, no. 14 (2013): 33. http://dx.doi.org/10.1007/s15006-013-2034-2.

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4

Akhundova, Maleyka, and Sabina Majidova. "HEERFORDT-WALDENSTRÖM SYNDROME (CLINICAL CASE)." Azerbaijan Journal of Ophthalmology, no. 2025/17/01/52 (April 8, 2025): 71–79. https://doi.org/10.71110/ajo791020251701527179.

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The article presents a clinical case of Heerfordt-Waldenström syndrome of patient A.Sh., born in 1972, who was undergoing inpatient treatment at the National Ophthalmology Centre named after Academician Zarifa Aliyeva. This syndrome manifested itself as anterior uveitis, facial nerve paralysis and of bilateral parotitis in anamnesis. Based on specific and ophthalmological examination, the following diagnosis was made: “Sarcoidosis, Heerfordt-Waldenström syndrome, uveitis, uveitic ocular hypertension of the right eye”. Appropriate complex therapy was carried out and a positive result was obtain
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5

Fardet, Laurence, and Alain Dupuy. "Syndrome de Heerfordt." La Presse Médicale 34, no. 9 (2005): 688. http://dx.doi.org/10.1016/s0755-4982(05)84014-x.

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6

İ, Arıkan F., Çetin F, Ağras P. I, Zengin T, Çataklı T, and Dallar Bilge Y. "Adölesan dönemde Heerfordt sendromu." Ege Tıp Dergisi 53, no. 3 (2014): 158–60. http://dx.doi.org/10.19161/etd.344076.

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7

Ikeda, Minoru, Kazuhito Yamada, Hidetoshi Kawamoto, Kumiko Yamada, and Hiroshi Tomita. "Facial Paralysis of Heerfordt Syndrome." Practica oto-rhino-laryngologica. Suppl. 1995, Supplement79 (1995): 166–71. http://dx.doi.org/10.5631/jibirinsuppl1986.1995.supplement79_166.

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8

Blair, Michael P. "Heerfordt Syndrome With Internal Ophthalmoplegia." Archives of Ophthalmology 123, no. 7 (2005): 1017. http://dx.doi.org/10.1001/archopht.123.7.1017.

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9

MOHN, ARNE. "EIN FALL VON FEBRIS UVEOZAROTIDEA (HEERFORDT)." Acta Ophthalmologica 11, no. 3 (2009): 397–403. http://dx.doi.org/10.1111/j.1755-3768.1933.tb07953.x.

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10

Patel, Pujan, Sebastian Mikulic, Sandra Sheffield, Catarina Canha, and Gladys Velarde. "HEERFORDT SYNDROME MANIFESTING AS CARDIAC SARCOIDOSIS." Journal of the American College of Cardiology 75, no. 11 (2020): 2653. http://dx.doi.org/10.1016/s0735-1097(20)33280-0.

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11

Sagowski, C., and J. Ußmüller. "Zur klinischen Diagnostik der Speicheldrüsensarkoidose (Heerfordt-Syndrom)." HNO 48, no. 8 (2000): 613–15. http://dx.doi.org/10.1007/s001060050624.

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12

Maharaj, Satish, Megan Brown, Karan Seegobin, and Carmen Isache. "Sarcoidosis presenting with facial swelling (Heerfordt syndrome)." Clinical Case Reports 6, no. 10 (2018): 2023–24. http://dx.doi.org/10.1002/ccr3.1741.

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13

Jonas, M., M. Barenbrock, J. Sciuk, O. Schober, and R. Schamberger. "67Ga-Szintigraphie bei akuter Sarkoidose mit Heerfordt-Syndrom." Nuklearmedizin 34, no. 01 (1995): 47–49. http://dx.doi.org/10.1055/s-0038-1629692.

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ZusammenfassungDie Sarkoidose ist eine chronische Systemerkrankung unbekannter Ätiologie, die durch nichtverkäsende epitheloidzellige Granulome gekennzeichnet ist. Wir berichten über eine 29jährige Patientin mit akuter Sarkoidose und Heerfordt-Syndrom (Parotisschwellung, Iridozyklitis und Fazialisparese), bei der zwar eine typische klinische Befundkonstellation vorlag, die transbronchiale Lungenbiopsie jedoch histologisch keinen granulomatösen Entzündungsprozeß nachweisen konnte. Die 67Ga-Szintigraphie zeigte ein so typisches Anreicherungsmuster, daß trotz negativer Histologie die Diagnose ges
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14

Yaremenko, A. I., A. Ya Razumova, S. I. Kutukova, and P. M. Baikalova. "Heerfordt-Waldenström disease. Report of two clinical cases." Stomatologiya 98, no. 6 (2019): 117. http://dx.doi.org/10.17116/stomat201998061117.

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15

Fraga, Rafael Cavanellas, Priscila Kakizaki, Neusa Yuriko Sakai Valente, Larissa Karine Leite Portocarrero, Mônica Fernandes Senise Teixeira, and Priscilla Fernandes Senise. "Do you know this syndrome? Heerfordt-Waldenström syndrome." Anais Brasileiros de Dermatologia 92, no. 4 (2017): 571–72. http://dx.doi.org/10.1590/abd1806-4841.20175211.

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16

Razzak, A., G. Belalami, J. Mohad, et al. "745 Sarcoïdose révélée par un syndrome de Heerfordt." Journal Français d'Ophtalmologie 32 (April 2009): 1S221. http://dx.doi.org/10.1016/s0181-5512(09)73870-7.

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17

Walter, C., A. Schwarting, T. Hansen, and G. Weibrich. "Das Heerfordt-Syndrom ? eine seltene Erstmanifestation der Sarkoidose." Mund-, Kiefer- und Gesichtschirurgie 9, no. 1 (2005): 43–47. http://dx.doi.org/10.1007/s10006-004-0582-4.

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18

KHAN, ANOSH A., APURVA KETKAR, RICHA DUA, MAHRUKH KHAN, DOUG ROSS, and SHARON M. WEINER. "HEERFORDT-WALDENSTORM SYNDROME: AN ATYPICAL VARIANT OF SARCOIDOSIS." CHEST 164, no. 4 (2023): A5724—A5725. http://dx.doi.org/10.1016/j.chest.2023.07.3692.

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19

Grönblad, Ester. "Mikulicz's Syndrome, Uveoparotid Fever (Heerfordt) and Keratoconjunctivitis sicca (Sjögren)." Acta Medica Scandinavica 95, S89 (2009): 316–26. http://dx.doi.org/10.1111/j.0954-6820.1938.tb19309.x.

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20

GRANSTRÖM, K. O., E. GRIPWALL, C. E. KRISTOFFERSON, and Å. G. H. LINDGREN. "A Case of Uveoparotid Fever (Heerfordt) with Autopsy Findings." Acta Medica Scandinavica 126, no. 4-5 (2009): 307–18. http://dx.doi.org/10.1111/j.0954-6820.1946.tb19022.x.

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21

Shiraishi, Ken, Yasushi Sadamoto, and Koji Sayama. "Heerfordt syndrome developing in a patient with cutaneous sarcoidosis." Australasian Journal of Dermatology 60, no. 3 (2019): 240–41. http://dx.doi.org/10.1111/ajd.12967.

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22

Fujita, Hiroyuki, Fumihisa Hiraide, Atsushi Kawano, et al. "A Case of Incomplete Heerfordt Syndrome Accompanied by Dysosmia." Practica Oto-Rhino-Laryngologica 90, no. 1 (1997): 19–24. http://dx.doi.org/10.5631/jibirin.90.19.

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23

Denny, M. Carter, and A. Domnica Fotino. "The Heerfordt-Waldenström Syndrome as an Initial Presentation of Sarcoidosis." Baylor University Medical Center Proceedings 26, no. 4 (2013): 390–92. http://dx.doi.org/10.1080/08998280.2013.11929014.

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24

ROOS, BERTIL. "Cerebral manifestations of lymphogranulomatosis benigna (Schaumann) and uveoparotid fever (Heerfordt)." Acta Medica Scandinavica 104, no. 1-2 (2009): 123–30. http://dx.doi.org/10.1111/j.0954-6820.1940.tb13608.x.

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25

SLOT, W. J. BRUINS, J. GOEDBLOED, and J. GOSLINGS. "Die Besnier-Boeck-(Schaumann-)sche Krankheit und die Uveo-Parotitis (Heerfordt)." Acta Medica Scandinavica 94, no. 1-2 (2009): 74–97. http://dx.doi.org/10.1111/j.0954-6820.1938.tb13593.x.

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26

Sakikawa, Aya, Isao Suzaki, Kei Sakikawa, et al. "A Case of Complete Heerfordt Syndrome Presenting with Facial Nerve Paralysis." Practica Oto-Rhino-Laryngologica 117, no. 11 (2024): 1011–17. http://dx.doi.org/10.5631/jibirin.117.1011.

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27

Fischer, T., M. M�hler, D. Beyersdorff, et al. "Einsatz moderner Ultraschallverfahren in der Diagnostik der Speicheldr�sensarkoidose (Heerfordt-Syndrom)." HNO 51, no. 5 (2003): 394–99. http://dx.doi.org/10.1007/s00106-002-0717-6.

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28

Fakih, Hafiz Abdul Moiz, Jonathan Fida Hussain, Salim Daouk, and Michael Jantz. "The Great Masquerader: Heerfordt Syndrome as an Initial Manifestation of Sarcoidosis." Chest 150, no. 4 (2016): 1052A. http://dx.doi.org/10.1016/j.chest.2016.08.1159.

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29

Petropoulos, I., J. P. Zuber, and Y. Guex-Crosier. "Heerfordt Syndrome with Unilateral Facial Nerve Palsy: A Rare Presentation of Sarcoidosis." Klinische Monatsblätter für Augenheilkunde 225, no. 5 (2008): 453–56. http://dx.doi.org/10.1055/s-2008-1027356.

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30

JERSILD, MOGENS. "The syndrome of Heerfordt (uveo-parotid fever), a manifestation of Boeck's sarcoid." Acta Medica Scandinavica 97, no. 3-4 (2009): 322–28. http://dx.doi.org/10.1111/j.0954-6820.1938.tb09977.x.

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31

Bergner, Raoul, and Christian Löffler. "Renale Sarkoidose." Arthritis und Rheuma 44, no. 05 (2024): 318–23. http://dx.doi.org/10.1055/a-2329-1156.

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ZUSAMMENFASSUNGDie Sarkoidose ist in Nordeuropa die häufigste granulomatöse Erkrankung. Man unterscheidet zwischen akuten Formen der Sarkoidose (Löfgren-Syndrom, Heerfordt-Syndrom) und der chronischen Sarkoidose. Die chronische Sarkoidose kann nahezu alle Organe betreffen. Die Lunge ist das am häufigsten betroffene Organ. Die Niere ist mit ca. 30 % der Fälle bei gründlicher Diagnostik nach der Lunge eines der am häufigsten mitbeteiligten Organe. Die in der Diagnostik gefundenen Befunde sind jedoch meistens wenig spektakulär und reichen von einer geringen Proteinurie über eine sterile Leukozytu
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32

OTANI, Kazuhiro, Kentaro NODA, Taro UKICHI, Isamu KINGETSU, and Daitaro KUROSAKA. "A case of abortive type of Heerfordt syndrome associated with paralysis of trigeminal nerve." Japanese Journal of Clinical Immunology 36, no. 2 (2013): 115–21. http://dx.doi.org/10.2177/jsci.36.115.

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33

Hirai, Toshiaki, Shinji Miyagawa, Kazutaka Matsui, and Akira Kurita. "Small fiber neuropathy in a patient with complete Heerfordt syndrome manifesting as refractory facial pain." Rinsho Shinkeigaku 54, no. 7 (2014): 585–88. http://dx.doi.org/10.5692/clinicalneurol.54.585.

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34

With, Torben K. "LA FEBRIS UVEO-PAROTIDEA (HEERFORDT) EST-ELLE UNE MANIFESTATION DE LYMFOCRANULOMATOSIS BENIGNA (SCHAUMANN)? ETUDE CLINIQUE." Acta Ophthalmologica 15, no. 1 (2009): 104–8. http://dx.doi.org/10.1111/j.1755-3768.1937.tb08688.x.

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35

Gallo, Chiara, Letizia Mazzini, Claudia Varrasi, Domizia Vecchio, Eleonora Virgilio, and Roberto Cantello. "Bilateral Facial Palsy as the Onset of Neurosarcoidosis: A Case Report and a Revision of Literature." NeuroSci 3, no. 2 (2022): 321–31. http://dx.doi.org/10.3390/neurosci3020023.

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Unilateral facial nerve palsy (FNP) is one of the most common cranial mononeuropathies. Among rare etiologies, neurosarcoidosis (NS) can cause bilateral involvement (both recurring and simultaneous) only in 15% to 25% of cases. The rarity of this systemic disease and its clinical heterogeneity, due to granulomatous inflammation that may affect many anatomic substrates, frequently make the diagnosis a real challenge for the clinician. Based on laboratory and instrumental tests, a careful diagnostic algorithm must be adopted to avoid misdiagnosis and delay in treatment. We present a 52-year-old
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36

Sugawara, Yoshifumi, Kenshi Sakayama, Eiji Sada, et al. "Heerfordt Syndrome Initially Presenting With Subcutaneous Mass Lesions: Usefulness of Gallium-67 Scans Before and After Treatment." Clinical Nuclear Medicine 30, no. 11 (2005): 732–33. http://dx.doi.org/10.1097/01.rlu.0000182264.76461.74.

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37

Heckmann, Josef, Christoph Lang, Peter Urban, et al. "Therapie der idiopathischen Fazialisparese (Bell’s palsy)." Aktuelle Neurologie 44, no. 10 (2017): 712–27. http://dx.doi.org/10.1055/s-0043-118088.

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ZusammenfassungDie periphere Fazialisparese ist die häufigste Hirnnervenläsion und wird klinisch diagnostiziert. Neurophysiologische Zusatzuntersuchungen können ergänzend zur Differenzierung und Prognoseabschätzung herangezogen werden. Der Anteil idiopathischer Fazialisparesen beträgt 60 – 75 %. Die übrigen 25 – 40 % lassen sich mit einer definierten Ätiologie in Zusammenhang bringen. Am häufigsten sind dabei die Neuroborreliose und der Zoster oticus (Ramsay-Hunt-Syndrom), seltener andere Infektionen. Weitere mögliche Auslöser sind die Sarkoidose (Heerfordt-Syndrom), das Sjögren-Syndrom, eine
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38

Yagi, Takuya, Hidenori Hattori, Masayuki Ohira, et al. "Progressive multifocal leukoencephalopathy developed in incomplete Heerfordt syndrome, a rare manifestation of sarcoidosis, without steroid therapy responding to cidofovir." Clinical Neurology and Neurosurgery 112, no. 2 (2010): 153–56. http://dx.doi.org/10.1016/j.clineuro.2009.10.005.

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39

Fujiwara, Keishi, Yasushi Furuta, and Satoshi Fukuda. "Two Cases of Heerfordt’s Syndrome: A Rare Manifestation of Sarcoidosis." Case Reports in Otolaryngology 2016 (2016): 1–4. http://dx.doi.org/10.1155/2016/3642735.

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Heerfordt’s syndrome is a rare manifestation of sarcoidosis characterized by the presence of facial nerve palsy, parotid gland enlargement, anterior uveitis, and low grade fever. Two cases of Heerfordt’s syndrome and a literature review are presented.Case 1. A 53-year-old man presented with swelling of his right eyelid, right facial nerve palsy, and swelling of his right parotid gland. A biopsy specimen from the swollen eyelid indicated sarcoidosis and he was diagnosed with incomplete Heerfordt’s syndrome based on the absence of uveitis. His symptoms were improved by corticosteroid therapy.Cas
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40

Hubbard, Richard, Victoria Carter, William Henley, and David Price. "Re “Inhaled Corticosteroid Particle Size and Risk of Hospitalization Rue to Exacerbations and All-Cause Mortality in Patients With Chronic Obstructive Respiratory Disease. A Nationwide Cohort Study”. Heerfordt et al [Letter]." International Journal of Chronic Obstructive Pulmonary Disease Volume 20 (February 2025): 243–44. https://doi.org/10.2147/copd.s514150.

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41

Ahmed, Syed Mohaimeen, Anika Hossain, Md Rihan Azad, Mohammad Sakhawat Hossen Khan, and Md Rashedul Islam. "Heerfordt’s syndrome: an uncommon manifestation of sarcoidosis." BIRDEM Medical Journal 11, no. 1 (2020): 67–69. http://dx.doi.org/10.3329/birdem.v11i1.51033.

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Heerfordt’s syndrome – the combination of facial palsy, parotid swelling, anterior uveitis and fever, is a rare manifestation of sarcoidosis. Here, we present case history of a patient with bilateral lower motor neuron facial nerve palsy, who was found to have bilateral parotid gland swelling and bilateral hilar lymphadenopathy. Computed tomography guided fine needle aspiration cytology from hilar lymph node findings were consistent with sarcoidosis. Subsequently, based on clinical features and cytological findings, the case was diagnosed as incomplete Heerfordt’s syndrome.
 Birdem Med J
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42

Dostálová, Lucie, David Kalfeřt, Alžběta Fíková, Martin Kuchař, and Jan Plzák. "Heerfordt’s syndrom – a rare manifestation of sarcoidosis from an ENT perspective." Otorinolaryngologie a foniatrie 72, no. 1 (2023): 33–35. http://dx.doi.org/10.48095/ccorl202333.

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Summary Sarcoidosis is a systemic granulomatous disease that mainly affects the pulmonary and lymphatic systems. In its rare, acute forms, it can manifest as Lofgren’s syndrome (combination of erythema nodosum, bilateral pulmonary hilar lymphadenopathy, joint pain, fever and general symptoms) and even more rarely as Heerfordt’s syndrome (combination of fever, anterior uveitis, bilateral edema of the parotid area and uni or bilateral facial nerve paresis). Although this dia­gnosis is rare, it belongs to the differential dia­gnosis of sudden paresis of the facial nerve and swelling of the paroti
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43

Arikan, F., F. Ozkan, P. I. Agras, T. Zengin, T. Catakli, and Y. D. Bilge. "513 HeerfordtS Syndrom in an Adolescent Boy." Archives of Disease in Childhood 97, Suppl 2 (2012): A149. http://dx.doi.org/10.1136/archdischild-2012-302724.0513.

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44

Dua, Anisha, and Augustine Manadan. "Heerfordt's Syndrome, or Uveoparotid Fever." New England Journal of Medicine 369, no. 5 (2013): 458. http://dx.doi.org/10.1056/nejmicm1303454.

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45

Tanaka, Saichiroh, Ryozo Umeda, Kazuhisa Kitagawa, Yumiko Tajika, and Astuo Miwa. "A case of Heerfordt's syndrome." Practica Oto-Rhino-Laryngologica 80, no. 9 (1987): 1363–67. http://dx.doi.org/10.5631/jibirin.80.1363.

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46

Di Stefano, Fabio, Roberto Paganelli, Nicola Verna, and Mario Di Gioacchino. "Cardiac sarcoidosis presenting as Heerfordt’s syndrome." American Journal of Medicine 112, no. 7 (2002): 594–95. http://dx.doi.org/10.1016/s0002-9343(02)01067-7.

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47

SANDBACKA-HOLMSTRÖM, I. "Schaumann's Disease and Heerfordt's, Subchronic uveoparotid Fever“." Acta Medica Scandinavica 103, no. 3-5 (2009): 482–85. http://dx.doi.org/10.1111/j.0954-6820.1940.tb11889.x.

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48

Tana, Claudio, Marco Tana, Giulio Cocco, Andrea Mezzetti, and Cosima Schiavone. "Atypical variant of Heerfordt's syndrome: Ultrasound findings." European Journal of Internal Medicine 24 (October 2013): e181. http://dx.doi.org/10.1016/j.ejim.2013.08.466.

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49

Srirangaramasamy, Jamunarani, and Shakthesh Kathirvelu. "A Rare Case of Heerfordt’s Syndrome with Bilateral Facial Palsy." Indian Journal of Otolaryngology and Head & Neck Surgery 71, S2 (2016): 1027–29. http://dx.doi.org/10.1007/s12070-016-0964-6.

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50

Glocker, F. X., C. Seifert, and C. H. L�cking. "Facial palsy in Heerfordt's syndrome: Electrophysiological localization of the lesion." Muscle & Nerve 22, no. 9 (1999): 1279–82. http://dx.doi.org/10.1002/(sici)1097-4598(199909)22:9<1279::aid-mus18>3.0.co;2-#.

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