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1

Kittisupamongkol, W. "Heerfordt syndrome." QJM 102, no. 2 (October 8, 2008): 149. http://dx.doi.org/10.1093/qjmed/hcn156.

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2

Larsen, Victor. "CHRISTIAN HEERFORDT." Acta Ophthalmologica 31, no. 5 (May 27, 2009): 397–99. http://dx.doi.org/10.1111/j.1755-3768.1953.tb07658.x.

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3

Füeßl, H. S. "Heerfordt-Syndrom." MMW - Fortschritte der Medizin 155, no. 14 (August 2013): 33. http://dx.doi.org/10.1007/s15006-013-2034-2.

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4

Fardet, Laurence, and Alain Dupuy. "Syndrome de Heerfordt." La Presse Médicale 34, no. 9 (May 2005): 688. http://dx.doi.org/10.1016/s0755-4982(05)84014-x.

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5

İ, Arıkan F., Çetin F, Ağras P. I, Zengin T, Çataklı T, and Dallar Bilge Y. "Adölesan dönemde Heerfordt sendromu." Ege Tıp Dergisi 53, no. 3 (September 1, 2014): 158–60. http://dx.doi.org/10.19161/etd.344076.

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6

Ikeda, Minoru, Kazuhito Yamada, Hidetoshi Kawamoto, Kumiko Yamada, and Hiroshi Tomita. "Facial Paralysis of Heerfordt Syndrome." Practica oto-rhino-laryngologica. Suppl. 1995, Supplement79 (1995): 166–71. http://dx.doi.org/10.5631/jibirinsuppl1986.1995.supplement79_166.

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7

Blair, Michael P. "Heerfordt Syndrome With Internal Ophthalmoplegia." Archives of Ophthalmology 123, no. 7 (July 1, 2005): 1017. http://dx.doi.org/10.1001/archopht.123.7.1017.

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8

MOHN, ARNE. "EIN FALL VON FEBRIS UVEOZAROTIDEA (HEERFORDT)." Acta Ophthalmologica 11, no. 3 (May 27, 2009): 397–403. http://dx.doi.org/10.1111/j.1755-3768.1933.tb07953.x.

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9

Patel, Pujan, Sebastian Mikulic, Sandra Sheffield, Catarina Canha, and Gladys Velarde. "HEERFORDT SYNDROME MANIFESTING AS CARDIAC SARCOIDOSIS." Journal of the American College of Cardiology 75, no. 11 (March 2020): 2653. http://dx.doi.org/10.1016/s0735-1097(20)33280-0.

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10

Sagowski, C., and J. Ußmüller. "Zur klinischen Diagnostik der Speicheldrüsensarkoidose (Heerfordt-Syndrom)." HNO 48, no. 8 (August 16, 2000): 613–15. http://dx.doi.org/10.1007/s001060050624.

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11

Maharaj, Satish, Megan Brown, Karan Seegobin, and Carmen Isache. "Sarcoidosis presenting with facial swelling (Heerfordt syndrome)." Clinical Case Reports 6, no. 10 (September 5, 2018): 2023–24. http://dx.doi.org/10.1002/ccr3.1741.

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12

Jonas, M., M. Barenbrock, J. Sciuk, O. Schober, and R. Schamberger. "67Ga-Szintigraphie bei akuter Sarkoidose mit Heerfordt-Syndrom." Nuklearmedizin 34, no. 01 (1995): 47–49. http://dx.doi.org/10.1055/s-0038-1629692.

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ZusammenfassungDie Sarkoidose ist eine chronische Systemerkrankung unbekannter Ätiologie, die durch nichtverkäsende epitheloidzellige Granulome gekennzeichnet ist. Wir berichten über eine 29jährige Patientin mit akuter Sarkoidose und Heerfordt-Syndrom (Parotisschwellung, Iridozyklitis und Fazialisparese), bei der zwar eine typische klinische Befundkonstellation vorlag, die transbronchiale Lungenbiopsie jedoch histologisch keinen granulomatösen Entzündungsprozeß nachweisen konnte. Die 67Ga-Szintigraphie zeigte ein so typisches Anreicherungsmuster, daß trotz negativer Histologie die Diagnose gestellt werden konnte.
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13

Yaremenko, A. I., A. Ya Razumova, S. I. Kutukova, and P. M. Baikalova. "Heerfordt-Waldenström disease. Report of two clinical cases." Stomatologiya 98, no. 6 (2019): 117. http://dx.doi.org/10.17116/stomat201998061117.

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14

Fraga, Rafael Cavanellas, Priscila Kakizaki, Neusa Yuriko Sakai Valente, Larissa Karine Leite Portocarrero, Mônica Fernandes Senise Teixeira, and Priscilla Fernandes Senise. "Do you know this syndrome? Heerfordt-Waldenström syndrome." Anais Brasileiros de Dermatologia 92, no. 4 (August 2017): 571–72. http://dx.doi.org/10.1590/abd1806-4841.20175211.

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15

Razzak, A., G. Belalami, J. Mohad, H. Bada, M. El Belhadji, R. Rachid, A. Chakib, K. Zaghloul, and A. Amraoui. "745 Sarcoïdose révélée par un syndrome de Heerfordt." Journal Français d'Ophtalmologie 32 (April 2009): 1S221. http://dx.doi.org/10.1016/s0181-5512(09)73870-7.

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16

Walter, C., A. Schwarting, T. Hansen, and G. Weibrich. "Das Heerfordt-Syndrom ? eine seltene Erstmanifestation der Sarkoidose." Mund-, Kiefer- und Gesichtschirurgie 9, no. 1 (January 2005): 43–47. http://dx.doi.org/10.1007/s10006-004-0582-4.

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17

Grönblad, Ester. "Mikulicz's Syndrome, Uveoparotid Fever (Heerfordt) and Keratoconjunctivitis sicca (Sjögren)." Acta Medica Scandinavica 95, S89 (April 24, 2009): 316–26. http://dx.doi.org/10.1111/j.0954-6820.1938.tb19309.x.

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18

GRANSTRÖM, K. O., E. GRIPWALL, C. E. KRISTOFFERSON, and Å. G. H. LINDGREN. "A Case of Uveoparotid Fever (Heerfordt) with Autopsy Findings." Acta Medica Scandinavica 126, no. 4-5 (April 24, 2009): 307–18. http://dx.doi.org/10.1111/j.0954-6820.1946.tb19022.x.

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19

Shiraishi, Ken, Yasushi Sadamoto, and Koji Sayama. "Heerfordt syndrome developing in a patient with cutaneous sarcoidosis." Australasian Journal of Dermatology 60, no. 3 (January 8, 2019): 240–41. http://dx.doi.org/10.1111/ajd.12967.

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20

Fujita, Hiroyuki, Fumihisa Hiraide, Atsushi Kawano, Kotaro Muto, Kouji Yoshiura, Akira Hagiwara, Yasuo Ogawa, and Shinya Ohashi. "A Case of Incomplete Heerfordt Syndrome Accompanied by Dysosmia." Practica Oto-Rhino-Laryngologica 90, no. 1 (1997): 19–24. http://dx.doi.org/10.5631/jibirin.90.19.

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21

Denny, M. Carter, and A. Domnica Fotino. "The Heerfordt-Waldenström Syndrome as an Initial Presentation of Sarcoidosis." Baylor University Medical Center Proceedings 26, no. 4 (October 2013): 390–92. http://dx.doi.org/10.1080/08998280.2013.11929014.

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22

ROOS, BERTIL. "Cerebral manifestations of lymphogranulomatosis benigna (Schaumann) and uveoparotid fever (Heerfordt)." Acta Medica Scandinavica 104, no. 1-2 (April 24, 2009): 123–30. http://dx.doi.org/10.1111/j.0954-6820.1940.tb13608.x.

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23

SLOT, W. J. BRUINS, J. GOEDBLOED, and J. GOSLINGS. "Die Besnier-Boeck-(Schaumann-)sche Krankheit und die Uveo-Parotitis (Heerfordt)." Acta Medica Scandinavica 94, no. 1-2 (April 24, 2009): 74–97. http://dx.doi.org/10.1111/j.0954-6820.1938.tb13593.x.

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24

Fakih, Hafiz Abdul Moiz, Jonathan Fida Hussain, Salim Daouk, and Michael Jantz. "The Great Masquerader: Heerfordt Syndrome as an Initial Manifestation of Sarcoidosis." Chest 150, no. 4 (October 2016): 1052A. http://dx.doi.org/10.1016/j.chest.2016.08.1159.

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25

Fischer, T., M. M�hler, D. Beyersdorff, H. Guski, M. Bollow, B. Hamm, M. Werbs, and S. Filimonow. "Einsatz moderner Ultraschallverfahren in der Diagnostik der Speicheldr�sensarkoidose (Heerfordt-Syndrom)." HNO 51, no. 5 (May 1, 2003): 394–99. http://dx.doi.org/10.1007/s00106-002-0717-6.

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26

Petropoulos, I., J. P. Zuber, and Y. Guex-Crosier. "Heerfordt Syndrome with Unilateral Facial Nerve Palsy: A Rare Presentation of Sarcoidosis." Klinische Monatsblätter für Augenheilkunde 225, no. 5 (May 2008): 453–56. http://dx.doi.org/10.1055/s-2008-1027356.

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27

JERSILD, MOGENS. "The syndrome of Heerfordt (uveo-parotid fever), a manifestation of Boeck's sarcoid." Acta Medica Scandinavica 97, no. 3-4 (April 24, 2009): 322–28. http://dx.doi.org/10.1111/j.0954-6820.1938.tb09977.x.

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28

OTANI, Kazuhiro, Kentaro NODA, Taro UKICHI, Isamu KINGETSU, and Daitaro KUROSAKA. "A case of abortive type of Heerfordt syndrome associated with paralysis of trigeminal nerve." Japanese Journal of Clinical Immunology 36, no. 2 (2013): 115–21. http://dx.doi.org/10.2177/jsci.36.115.

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29

Hirai, Toshiaki, Shinji Miyagawa, Kazutaka Matsui, and Akira Kurita. "Small fiber neuropathy in a patient with complete Heerfordt syndrome manifesting as refractory facial pain." Rinsho Shinkeigaku 54, no. 7 (2014): 585–88. http://dx.doi.org/10.5692/clinicalneurol.54.585.

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30

With, Torben K. "LA FEBRIS UVEO-PAROTIDEA (HEERFORDT) EST-ELLE UNE MANIFESTATION DE LYMFOCRANULOMATOSIS BENIGNA (SCHAUMANN)? ETUDE CLINIQUE." Acta Ophthalmologica 15, no. 1 (June 25, 2009): 104–8. http://dx.doi.org/10.1111/j.1755-3768.1937.tb08688.x.

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31

Gallo, Chiara, Letizia Mazzini, Claudia Varrasi, Domizia Vecchio, Eleonora Virgilio, and Roberto Cantello. "Bilateral Facial Palsy as the Onset of Neurosarcoidosis: A Case Report and a Revision of Literature." NeuroSci 3, no. 2 (May 29, 2022): 321–31. http://dx.doi.org/10.3390/neurosci3020023.

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Unilateral facial nerve palsy (FNP) is one of the most common cranial mononeuropathies. Among rare etiologies, neurosarcoidosis (NS) can cause bilateral involvement (both recurring and simultaneous) only in 15% to 25% of cases. The rarity of this systemic disease and its clinical heterogeneity, due to granulomatous inflammation that may affect many anatomic substrates, frequently make the diagnosis a real challenge for the clinician. Based on laboratory and instrumental tests, a careful diagnostic algorithm must be adopted to avoid misdiagnosis and delay in treatment. We present a 52-year-old woman with an acute onset of unilateral right FNP, rapidly developing contralateral involvement (simultaneous bilateral FNP). Lung findings pointed towards a systemic disease, and then lymph node biopsy confirmed NS. Corticosteroid therapy was started. After three years of follow-up, the patient is still in remission with a low prednisone dose. We discuss the differential diagnosis of bilateral FNP, focusing on clinical presentation, diagnosis, and treatment of NS. We have performed a literature revision, confirming bilateral FNP, outside Heerfordt syndrome, to be rare and sometimes represent the only neurological manifestation of NS onset.
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32

Sugawara, Yoshifumi, Kenshi Sakayama, Eiji Sada, Makoto Kajihara, Takatoshi Semba, Hiroshi Higashino, and Teruhito Mochizuki. "Heerfordt Syndrome Initially Presenting With Subcutaneous Mass Lesions: Usefulness of Gallium-67 Scans Before and After Treatment." Clinical Nuclear Medicine 30, no. 11 (November 2005): 732–33. http://dx.doi.org/10.1097/01.rlu.0000182264.76461.74.

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33

Heckmann, Josef, Christoph Lang, Peter Urban, Franz Glocker, Bruno Weder, Gudrun Reiter, Christian Bischoff, Uwe Meier, and Orlando Guntinas-Lichius. "Therapie der idiopathischen Fazialisparese (Bell’s palsy)." Aktuelle Neurologie 44, no. 10 (September 6, 2017): 712–27. http://dx.doi.org/10.1055/s-0043-118088.

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ZusammenfassungDie periphere Fazialisparese ist die häufigste Hirnnervenläsion und wird klinisch diagnostiziert. Neurophysiologische Zusatzuntersuchungen können ergänzend zur Differenzierung und Prognoseabschätzung herangezogen werden. Der Anteil idiopathischer Fazialisparesen beträgt 60 – 75 %. Die übrigen 25 – 40 % lassen sich mit einer definierten Ätiologie in Zusammenhang bringen. Am häufigsten sind dabei die Neuroborreliose und der Zoster oticus (Ramsay-Hunt-Syndrom), seltener andere Infektionen. Weitere mögliche Auslöser sind die Sarkoidose (Heerfordt-Syndrom), das Sjögren-Syndrom, eine Meningeosis carcinomatosa, das Melkersson-Rosenthal-Syndrom, das Guillain-Barré-Syndrom, raumfordernde Prozesse im Kleinhirnbrückenwinkel, Frakturen des Felsenbeins, Parotistumoren und otogene Prozesse.Patienten mit idiopathischer Fazialisparese sollen mit Glukokortikoiden behandelt werden. Steroide begünstigen die vollständige Rückbildung und verringern das Risiko von Synkinesien, autonomen Störungen sowie Kontrakturen (Number needed to treat [NNT] 10; 95 % KI 6 – 20). Eine zusätzliche virustatische Therapie kann bei nur dezentem zusätzlichen Nutzen (< 7 %) nicht generell empfohlen werden. Patienten mit Fazialisparesen durch eine definierte Ätiologie werden ursachenbezogen behandelt. In der klinischen Praxis bewährt hat sich die symptomatische Therapie (Dexpanthenol-Augensalbe, Uhrglasverband) zum Schutz der Hornhaut. Eine zusätzliche Übungsbehandlung ist aus psychologischen Gründen angeraten. Nach Defektheilung können Methoden der Lidbeschwerung oder eine Tarsorrhaphie zur Erzielung eines hinreichenden Lidschlusses durchgeführt werden. In Einzelfällen sind operative mikrochirurgische Behandlungsmöglichkeiten zur Reanimation des N. fazialis in Betracht zu ziehen. Bei Schwangeren gelten grundsätzlich die gleichen diagnostischen und therapeutischen Prinzipien.
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34

Yagi, Takuya, Hidenori Hattori, Masayuki Ohira, Kazuo Nakamichi, Mutsuyo Takayama-Ito, Masayuki Saijo, Toshihiko Shimizu, Daisuke Ito, Kazushi Takahashi, and Norihiro Suzuki. "Progressive multifocal leukoencephalopathy developed in incomplete Heerfordt syndrome, a rare manifestation of sarcoidosis, without steroid therapy responding to cidofovir." Clinical Neurology and Neurosurgery 112, no. 2 (February 2010): 153–56. http://dx.doi.org/10.1016/j.clineuro.2009.10.005.

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35

Fujiwara, Keishi, Yasushi Furuta, and Satoshi Fukuda. "Two Cases of Heerfordt’s Syndrome: A Rare Manifestation of Sarcoidosis." Case Reports in Otolaryngology 2016 (2016): 1–4. http://dx.doi.org/10.1155/2016/3642735.

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Heerfordt’s syndrome is a rare manifestation of sarcoidosis characterized by the presence of facial nerve palsy, parotid gland enlargement, anterior uveitis, and low grade fever. Two cases of Heerfordt’s syndrome and a literature review are presented.Case 1. A 53-year-old man presented with swelling of his right eyelid, right facial nerve palsy, and swelling of his right parotid gland. A biopsy specimen from the swollen eyelid indicated sarcoidosis and he was diagnosed with incomplete Heerfordt’s syndrome based on the absence of uveitis. His symptoms were improved by corticosteroid therapy.Case 2. A 55-year-old woman presented with left facial nerve palsy, bilateral hearing loss, and swelling of her bilateral parotid glands. She had been previously diagnosed with uveitis and bilateral hilar lymphadenopathy. Although no histological confirmation was performed, she was diagnosed with complete Heerfordt’s syndrome on the basis of her clinical symptoms. Swelling of the bilateral parotid glands and left facial nerve palsy were improved immediately by corticosteroid therapy. Sarcoidosis is a relatively uncommon disease for the otolaryngologist. However, the otolaryngologist may encounter Heerfordt’s syndrome as this syndrome presents with facial nerve palsy and swelling of the parotid gland. Therefore, we otolaryngologists should diagnose and treat Heerfordt’s syndrome appropriately in cooperation with pneumologists and ophthalmologists.
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36

Ahmed, Syed Mohaimeen, Anika Hossain, Md Rihan Azad, Mohammad Sakhawat Hossen Khan, and Md Rashedul Islam. "Heerfordt’s syndrome: an uncommon manifestation of sarcoidosis." BIRDEM Medical Journal 11, no. 1 (December 31, 2020): 67–69. http://dx.doi.org/10.3329/birdem.v11i1.51033.

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Heerfordt’s syndrome – the combination of facial palsy, parotid swelling, anterior uveitis and fever, is a rare manifestation of sarcoidosis. Here, we present case history of a patient with bilateral lower motor neuron facial nerve palsy, who was found to have bilateral parotid gland swelling and bilateral hilar lymphadenopathy. Computed tomography guided fine needle aspiration cytology from hilar lymph node findings were consistent with sarcoidosis. Subsequently, based on clinical features and cytological findings, the case was diagnosed as incomplete Heerfordt’s syndrome. Birdem Med J 2021; 11(1): 67-69
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37

Arikan, F., F. Ozkan, P. I. Agras, T. Zengin, T. Catakli, and Y. D. Bilge. "513 HeerfordtS Syndrom in an Adolescent Boy." Archives of Disease in Childhood 97, Suppl 2 (October 1, 2012): A149. http://dx.doi.org/10.1136/archdischild-2012-302724.0513.

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38

Dua, Anisha, and Augustine Manadan. "Heerfordt's Syndrome, or Uveoparotid Fever." New England Journal of Medicine 369, no. 5 (August 2013): 458. http://dx.doi.org/10.1056/nejmicm1303454.

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39

Tanaka, Saichiroh, Ryozo Umeda, Kazuhisa Kitagawa, Yumiko Tajika, and Astuo Miwa. "A case of Heerfordt's syndrome." Practica Oto-Rhino-Laryngologica 80, no. 9 (1987): 1363–67. http://dx.doi.org/10.5631/jibirin.80.1363.

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40

Di Stefano, Fabio, Roberto Paganelli, Nicola Verna, and Mario Di Gioacchino. "Cardiac sarcoidosis presenting as Heerfordt’s syndrome." American Journal of Medicine 112, no. 7 (May 2002): 594–95. http://dx.doi.org/10.1016/s0002-9343(02)01067-7.

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41

SANDBACKA-HOLMSTRÖM, I. "Schaumann's Disease and Heerfordt's, Subchronic uveoparotid Fever“." Acta Medica Scandinavica 103, no. 3-5 (April 24, 2009): 482–85. http://dx.doi.org/10.1111/j.0954-6820.1940.tb11889.x.

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42

Tana, Claudio, Marco Tana, Giulio Cocco, Andrea Mezzetti, and Cosima Schiavone. "Atypical variant of Heerfordt's syndrome: Ultrasound findings." European Journal of Internal Medicine 24 (October 2013): e181. http://dx.doi.org/10.1016/j.ejim.2013.08.466.

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43

Glocker, F. X., C. Seifert, and C. H. L�cking. "Facial palsy in Heerfordt's syndrome: Electrophysiological localization of the lesion." Muscle & Nerve 22, no. 9 (September 1999): 1279–82. http://dx.doi.org/10.1002/(sici)1097-4598(199909)22:9<1279::aid-mus18>3.0.co;2-#.

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44

Srirangaramasamy, Jamunarani, and Shakthesh Kathirvelu. "A Rare Case of Heerfordt’s Syndrome with Bilateral Facial Palsy." Indian Journal of Otolaryngology and Head & Neck Surgery 71, S2 (February 19, 2016): 1027–29. http://dx.doi.org/10.1007/s12070-016-0964-6.

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45

Darlington, P., L. Tallstedt, L. Padyukov, I. Kockum, K. Cederlund, A. Eklund, and J. Grunewald. "HLA-DRB1* alleles and symptoms associated with Heerfordt's syndrome in sarcoidosis." European Respiratory Journal 38, no. 5 (May 12, 2011): 1151–57. http://dx.doi.org/10.1183/09031936.00025011.

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46

Rubin, Mark G., and Joseph W. McGoey. "Heerfordt's syndrome presenting with an erythematous eruption of the lower legs." Journal of the American Academy of Dermatology 13, no. 2 (August 1985): 314–16. http://dx.doi.org/10.1016/s0190-9622(85)80301-7.

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47

Tanaka, Moe, Takeshi Kawanobe, Yuki Horiguchi, Masakatsu Tokunaga, Kosuke Ito, Yuho Ishida, Hiroki Umezawa, et al. "A case report of sarcoidosis with Heerfordt’s syndrome diagnosed after 5 years." Japanese Journal of Sarcoidosis and Other Granulomatous Disorders 41, no. 1_2 (October 1, 2021): 71–75. http://dx.doi.org/10.7878/jjsogd.41.1_2_71.

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48

Bernardinello, Nicol, Simone Petrarulo, Elisabetta Balestro, Elisabetta Cocconcelli, Marcel Veltkamp, and Paolo Spagnolo. "Pulmonary Sarcoidosis: Diagnosis and Differential Diagnosis." Diagnostics 11, no. 9 (August 28, 2021): 1558. http://dx.doi.org/10.3390/diagnostics11091558.

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Sarcoidosis is a multisystem disorder of unknown origin and poorly understood pathogenesis that predominantly affects lungs and intrathoracic lymph nodes and is characterized by the presence of noncaseating granulomatous inflammation in involved organs. The disease is highly heterogeneous and can mimic a plethora of other disorders, making diagnosis a challenge even for experienced physicians. The evolution and severity of sarcoidosis are highly variable: many patients are asymptomatic and their disease course is generally benign with spontaneous resolution. However, up to one-third of patients develop chronic or progressive disease mainly due to pulmonary or cardiovascular complications that require long-term therapy. The diagnosis of sarcoidosis requires histopathological evidence of noncaseating granulomatous inflammation in one or more organs coupled with compatible clinical and radiological features and the exclusion of other causes of granulomatous inflammation; however, in the presence of typical disease manifestations such as Löfgren’s syndrome, Heerfordt’s syndrome, lupus pernio and asymptomatic bilateral and symmetrical hilar lymphadenopathy, the diagnosis can be established with high level of certainty on clinical grounds alone. This review critically examines the diagnostic approach to sarcoidosis and emphasizes the importance of a careful exclusion of alternative diagnoses.
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49

Wu, Danwei, Neda Sattarnezhad, Shefali Dujari, Christopher Bruce Lock, and May Han. "Heerfordt's syndrome with polyradiculopathy, a rare presentation of neurosarcoidosis: Case report and review of literature." Neuroimmunology Reports 2 (2022): 100087. http://dx.doi.org/10.1016/j.nerep.2022.100087.

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50

Fischer, T., S. Filimonow, J. Petersein, C. Zimmer, D. Beyersdorff, and H. Guski. "Diagnosis of Heerfordt's syndrome by state-of-the-art ultrasound in combination with parotid biopsy: a case report." European Radiology 12, no. 1 (April 6, 2001): 134–37. http://dx.doi.org/10.1007/s003300100879.

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