Academic literature on the topic 'Heather Trials'
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Journal articles on the topic "Heather Trials"
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Niers, H., and J. van der Boon. "Effect of black peat, pH and Mg on growth of heather on sandy soil." Netherlands Journal of Agricultural Science 34, no. 1 (February 1, 1986): 103–6. http://dx.doi.org/10.18174/njas.v34i1.16820.
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Eight field trials were carried out with various heather cultivars (Calluna vulgaris Carmen, Cuprea, Robert Chapman; Erica tetralix Con Underwood; E. carnea [herbacea] King George and E. cinerea C.D. Eason). Peat at 0-8 msuperscript 3/100 msuperscript 2 was incorporated into the top soil or applied as a layer and soil pH-KCl was maintained at levels between 3 and 6.8. Increasing peat application up to 4 msuperscript 3/100 msuperscript 2 improved the growth and quality (visual rating) of the stand; higher amounts had little additional effect. Peat applied as a layer gave some slightly better results than peat incorporated into the topsoil. A soil pH-KCl value of 4.2 was the optimum for growth of most cultivars and reasonable growth could be expected in the range 3.8-4.7. Cv. King George was more tolerant to high pH than cultivars of the other species tested. In 3 trials with Calluna cultivars MgO application at 150 or 200 kg/ha increased the Mg content of the soil and shoots but had a slight negative effect on growth. (Abstract retrieved from CAB Abstracts by CABI’s permission)
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Weetman, G. F., R. Fournier, J. Barker, E. Schnorbus-Panozzo, and A. Germain. "Foliar analysis and response of fertilized chlorotic Sitka spruce plantations on salal-dominated cedar–hemlock cutovers on Vancouver Island." Canadian Journal of Forest Research 19, no. 12 (December 1, 1989): 1501–11. http://dx.doi.org/10.1139/x89-229.
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A series of microplot and conventional plot trials were used to determine the nutritional status and required nutrient additions to bring young chlorotic Sitka spruce (Piceasitchensis (Bong.) Carr) plantations out of "check." Check occurs on clear-cut and burned old-growth western red cedar (Thujaplicata Donn ex D. Don) and western hemlock (Tsugaheterophylla (Raf.) Sarg.) stands in the Coastal Western Hemlock biogeoclimatic zone growing on deep morhumus Podzols invaded by dense salal (Gaultheriashallon). Microplot trials identified the requirement for N and P. Checked trees responded to fertilization immediately with a 4- to 8-year temporary increase in leader length. Grubbing out of aboveground salal did not improve tree nutrition. There is a close parallel to "heather check" noted with Sitka spruce in British and Irish moorlands; a possible allelopathic effect of salal is suspected. It is concluded that one or more N and P additions are required to establish crown closure. Fertilized Sitka spruce show a high incidence of spruce weevil attack. The deficient and optimum foliar nutrient concentrations developed in Britain for the diagnosis of Sitka spruce appear to be applicable.
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Krewer, G. W., K. S. Delaplane, and P. A. Thomas. "SCREENING PLANTS AS SUPPLEMENTAL FORAGES FOR POLLINATING BUMBLEBEES (BOMBUS SPP.)." HortScience 31, no. 5 (September 1996): 750c—750. http://dx.doi.org/10.21273/hortsci.31.5.750c.
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Bumblebees (Bombus spp.) are important pollinators of mostly self-sterile rabbiteye blueberry (Vaccinium ashei Reade). Annual bee colonies start from solitary overwintered queens who emerge in near-synchrony with rabbiteye blueberry bloom. Although colony populations may reach several hundred individuals by midsummer, in early spring most Bombus visiting rabbiteye blueberry are queens reared the previous season. Thus, practices that encourage production of queens in summer may increase populations of blueberry pollinators the next spring. In south Georgia, midsummer shortages of nectar-yielding plants may nutritionally limit queen production, and cultured bee forages may help overcome this deficiency. Candidate plants must not compete with the crop for pollinators, and they must be attractive to bees, easy to grow, vigorous, and non-invasive. In 3 years of trials, the following plants have shown promise as supplemental bumblebee forages in south Georgia: Althea (Hibiscus syriacus), abelia (Abelia ×grandifolia), vitex (Vitex agnuscastus), red clover (Trifolium pratense perenne), Mexican heather (Cuphea hyssopifolia), monkey grass (Liriope muscari), summer sweet (Clethra alnifolia), and giant sunflower (Helianthus giganteus).
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Kerslake, J. E., L. E. B. Kruuk, S. E. Hartley, and S. J. Woodin. "Winter moth (Operophtera brumata (Lepidoptera: Geometridae)) outbreaks on Scottish heather moorlands: effects of host plant and parasitoids on larval survival and development." Bulletin of Entomological Research 86, no. 2 (April 1996): 155–64. http://dx.doi.org/10.1017/s0007485300052391.
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AbstractOutbreaks of the winter moth, Operophtera brumata Linnaeus (Lepidoptera: Geometridae), have recently become widespread on heather moorlands in northeast Scotland. These outbreaks represent remarkable phenomena given the poor nutritional quality of the dominant moorland host plant Calluna vulgaris (Linnaeus) Hull (Ericaceae). Winter moth performance on C. vulgaris was compared with that on the other available moorland host plant, Vaccinium myrtillus (Linnaeus) (Ericaceae), and parasitism levels were measured in two moorland outbreak populations. Larval densities in the field were generally higher on Calluna than on Vaccinium. However, larvae showed better survival, more rapid development and greater pupal weights on Vaccinium than on Calluna. Feeding trials indicated that Vaccinium was more digestible than Calluna. No evidence of parasitism was found in a high-altitude moorland winter moth outbreak population from mainland Scotland, but the parasitoid Phobocampe neglecta (Holmgren) (Hymenoptera: Ichneumonidae) was present in 27% of larvae from a lower-altitude moorland outbreak on Orkney. The results indicate that the presence of Vaccinium and the opportunity to escape from parasitism may facilitate O. brumata outbreak formation in high-altitude moorland sites. However, neither factor can provide a full explanation for the present phenomenon.
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Lobo, N., M. Duong, and J. S. Millar. "Conifer-seed preferences of small mammals." Canadian Journal of Zoology 87, no. 9 (September 2009): 773–80. http://dx.doi.org/10.1139/z09-070.
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The preferences of the deer mouse ( Peromyscus maniculatus (Wagner, 1845)), southern red-backed vole ( Myodes gapperi (Vigors, 1830)), heather vole ( Phenacomys intermedius Merriam, 1889), long-tailed vole ( Microtus longicaudus (Merriam, 1888)), and meadow vole ( Microtus pennsylvanicus (Ord, 1851)) for lodgepole pine ( Pinus contorta Dougl. ex Loud.), white spruce ( Picea glauca (Moench.) Voss), and subalpine fir ( Abies lasiocarpa (Hook.) Nutt.) seeds were investigated using cafeteria-style feeding experiments. Seed selection by P. maniculatus and M. gapperi in the field was also studied. Peromyscus maniculatus, M. gapperi, M. longicaudus, and M. pennsylvanicus showed a distinct preference for lodgepole pine seeds and avoidance of subalpine fir seeds, and consumed the different species of seeds in similar relative proportions. Phenacomys intermedius behaved very differently from the other rodent species in that it did not show a preference among seed species, and consumed very few seeds in total. Findings from the field seed selection trials were consistent with laboratory results. We suggest that postdispersal seed predation by small mammals could limit the recruitment success of lodgepole pine and white spruce, but would not be a major problem in the regeneration of subalpine fir stands. This could provide an advantage for subalpine fir over neighbouring competitive species.
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Braun, Ralph, Mayuri Sharma, Christina DeMaso, Allan Parker, David Dominguez, Heather Watkins, Hansi Dean, et al. "1051. Characterization of Immune Responses to a Live-Attenuated Tetravalent Dengue Vaccine." Open Forum Infectious Diseases 8, Supplement_1 (November 1, 2021): S617. http://dx.doi.org/10.1093/ofid/ofab466.1245.
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Abstract Background A safe and effective vaccine against dengue is needed to address an unmet medical need that affects a large portion of the world’s population. Takeda’s live attenuated tetravalent dengue vaccine candidate (TAK-003) has shown protection in an ongoing Phase 3 efficacy trial. TAK-003 contains an attenuated dengue type 2 virus (DENV-2), and 3 genetically modified viruses in which the structural proteins from each of the serotypes 1, 3 and 4 have been placed into the DENV-2 backbone. Exploratory immunological assessments have been a part of the TAK-003 clinical development plan to better understand the mechanisms of action of TAK-003, and to identify immune response signatures that may correlate with protection. Methods Cellular and humoral immune responses elicited by vaccination in dengue-naïve and dengue-exposed individuals were measured across several clinical trials. For the humoral response, several methods were used to measure the magnitude and characteristics of the antibodies following vaccination with TAK-003 including studies of neutralizing antibodies, antibodies that bind to the viral components of the vaccine, the affinity and complement fixing capabilities of antibodies specific to structural proteins, and additionally the level of antibodies specific to nonstructural protein 1 (NS1). Results A multifunctional cellular immune response was found following vaccination that primarily targeted nonstructural proteins in the DENV-2 backbone and was cross reactive to epitopes found in the other serotypes. The vaccine elicited neutralizing antibodies with high tetravalent seropositivity rates among participants. Further assessment of this response revealed that it consists of serotype-specific and cross-reactive neutralizing antibodies against all four serotypes. In addition, sera from vaccinated individuals neutralized genotypically diverse dengue strains. In addition to antibodies specific to structural components, antibodies to DENV-2 NS1 that were cross reactive to the NS1 proteins of the other serotypes were found. Conclusion The breadth of the cellular and humoral immune responses elicited by TAK-003 in vaccine recipients across a wide age range living in different endemicities aligns with the response profile expected of a multivalent live vaccine. Disclosures Ralph Braun, PhD, Takeda Pharmaceuticals (Employee) Mayuri Sharma, PhD, Takeda Pharmaceuticals (Employee) Christina DeMaso, n/a, Takeda Pharmaceuticals (Employee) Allan Parker, n/a, Takeda Pharmaceuticals (Employee) David Dominguez, n/a, Takeda Pharmaceuticals (Employee) Heather Watkins, n/a, Takeda Pharmaceuticals (Employee) Hansi Dean, PhD, Takeda Pharmaceuticals (Consultant) Lovkesh Karwal, n/a, Takeda Pharmaceuticals (Employee) Eduardo Nascimento, n/a, Takeda Pharmaceuticals (Employee) Nicole Messere, n/a, Takeda Pharmaceuticals (Employee) Isamu Tsuji, n/a, Takeda Pharmaceuticals (Employee) Melissa Zahralban-Steele, n/a, Takeda Pharmaceuticals (Employee) Jeffrey R. Currier, PhD, Takeda Pharmaceuticals (Scientific Research Study Investigator) Heather Friberg-Robertson, PhD, Takeda Pharmaceuticals (Scientific Research Study Investigator)
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Lewis, Tomiyuri, Stephanie Flores, Leah Sabacan, Patricia Choy, Halle Thannickal, Yiwey Shieh, Jeffrey Tice, et al. "Abstract P5-19-04: The WISDOM study: Reducing sequential steps and implementing parallel workflows in pragmatic trials." Cancer Research 82, no. 4_Supplement (February 15, 2022): P5–19–04—P5–19–04. http://dx.doi.org/10.1158/1538-7445.sabcs21-p5-19-04.
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Abstract Background:The WISDOM Study is a preference-tolerant pragmatic study, comparing annual mammograms to a risk-based screening. Eligibility includes women ages 40-74 years with no history of breast cancer or DCIS. Participants are enrolled to one study arm: annual screening or risk-based screening (includes genetic testing). Pragmatic trials often involve gathering real-time data over multiple time points. Collecting real-time data sequentially can limit enrollment, delay study assignments, and reduce participant engagement. The WISDOM Study has identified such bottlenecks and has implemented parallel workflows, reducing the overall wait time for participants to complete required study steps. These data highlight how moving participants through the study more efficiently can improve enrollment and retention and inform other pragmatic trials. Methods: WISDOM participants have the option to either choose their study arm or be randomized into one as part of the preference tolerant randomized trial design. Participants then complete breast health questionnaires and genetic testing (if in the risk-based arm). This information is analyzed by the WISDOM breast cancer risk assessment algorithm, the result of which is then communicated to the participant through a screening assignment letter (SAL). Specific data elements, such as breast density found participants’ mammogram reports and genetic testing results are required for study randomization process and risk assessment calculations, respectively. The WISDOM randomization algorithm is stratified by several factors, including breast cancer risk estimated using the Breast Cancer Surveillance Consortium (BCSC) model, which uses mammographic density as a key input variable. The study team changed the workflow to allow participants to proceed to randomization without specific information by imputing both density and risk. Additionally, a parallel workflow improvement process was implemented to obtain mammogram reports while genetic testing was being completed. Results: Before the weighted BCSC and imputed density algorithms were introduced, it took an average of 47 days to randomize participants after completion of the baseline enrollment questionnaires. Now, participants are randomized immediately which has reduced delays by 100%. Prior to implementing the parallel workflow for genetic testing and mammogram ascertainment, genetic testing kits were sent only after mammogram reports were collected and validated. The expected turnaround time for genetic testing results was 30-60 days and on average, results were returned to participants in 42 days. Streamlining the study design to obtain mammogram reports while participants complete their genetic testing has shortened the time for participants to receive their screening assignment letters (SALs) from an average of 160 days to 78 days, a reduction by 49%. In comparison, participants in the annual arm of the study who do not complete genetic testing, receive their SALs after an average of 38 days from enrollment. This is due to long wait times to obtain mammographic densities from outside medical facilities. Conclusions: Creating parallel data ascertainment workflows and reducing sequential steps in the study process has increased completion of individual enrollment activities. Participants now are randomized immediately upon joining the study and have access to their SALs and genetic results more rapidly. This approach eliminated randomization wait times and improved efficiency of the early in the enrollment process. We are evaluating the impact on participant retention going forward. Workflow efficiency is critical to improve the patient experience, and our learnings can inform future trial design, particularly for studies requiring data from outside sources. Citation Format: Tomiyuri Lewis, Stephanie Flores, Leah Sabacan, Patricia Choy, Halle Thannickal, Yiwey Shieh, Jeffrey Tice, Elad Ziv, Lisa Madlensky, Martin Eklund, Christina Yau, Amie Blanco, Barry Tong, Deborah Goodman, Nancy Anderson, Heather Harvey, Steele Fors, Hannah L Park, Samrrah Raouf, Skye Stewart, Janet Wernisch, Barbara Koenig, Celia Kaplan, Robert Hiatt, Neil Wenger, Vivian Lee, Diane Heditsian, Susie Brain, Dolores Moorehead, Barbara A Parker, Alexander Borowsky, Hoda Anton-Culver, Arash Naeim, Andrea Kaster, Laura van ‘t Veer, Andrea Z LaCroix, Olufunmilayo I Olopade, Deepa Sheth, Agustin Garcia, Rachel Lancaster, Michael Plaza, Wisdom Study, Athena Breast Health Network Investigators, Advocate Partners, Allison S Fiscalini, Laura Esserman. The WISDOM study: Reducing sequential steps and implementing parallel workflows in pragmatic trials [abstract]. In: Proceedings of the 2021 San Antonio Breast Cancer Symposium; 2021 Dec 7-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2022;82(4 Suppl):Abstract nr P5-19-04.
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Choy, Patricia, Tomiyuri Lewis, Stephanie Flores, Leah Sabacan, Halle Thannickal, Steffanie Goodman, Yiwey Shieh, et al. "Abstract P5-19-01: The impact of streamlined processes and patient-directed messaging to improve enrollment in a remote, pragmatic clinical trial." Cancer Research 82, no. 4_Supplement (February 15, 2022): P5–19–01—P5–19–01. http://dx.doi.org/10.1158/1538-7445.sabcs21-p5-19-01.
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Abstract Background Recent advances in technology have made it possible to conduct remote clinical trials that allow individuals to participate from home with comfort, privacy, and ease. Despite these advances, challenges persist in running remote trials, such as survey question redundancies, lack of patient-initiated data-sharing tools, and unclear patient communication around critical enrollment steps. The Women Informed to Screen Depending on Measures of risk (WISDOM) Study is a pragmatic, preference-tolerant randomized control breast cancer screening trial comparing personalized risk-based screening to traditional, annual screening. The study population includes women ages 40-74 without a history of breast cancer or DCIS. Since 2016, study enrollment has been available to all women in the U.S. who meet study eligibility criteria. Since October 2020, WISDOM has implemented multiple strategies to improve participant experience: participant-initiated data-sharing tools and clear participant messaging. This abstract presents the efficacy of these interventions as they relate to increasing patient enrollment in remote, pragmatic clinical trials. Methods The WISDOM Study online enrollment process includes registration, participant study arm selection or randomization, online consent, and enrollment (submission of multiple study surveys over a secure, online platform). Barriers to online enrollment were uncovered through an internally-conducted needs assessment of participants who enrolled between 2019-2020, and participant feedback obtained through phone interviews conducted by WISDOM’s embedded ethics study. Improvements to our online enrollment procedures were executed in October 2020 and included: improving the clarity of study arm selection options, streamlining data collection surveys, and enacting a secure, patient-initiated online data-sharing tool and an online portal feature with auto-launch of critical information. Study metrics were obtained through Google Analytics and Salesforce. Results Prior to the end of 2020, only 62% of the 30,046 participants who registered for the WISDOM Study completed study enrollment. After improving the enrollment process, of the 5,334 participants registered for the study between Jan-June 2021, 69% completed the enrollment process finishing both the online consent and survey forms. Conversion from consent to enrollment went from 78% in January 2020 to 93% in June 2021. Currently, 56% participants complete enrollment in one day. Streamlining online patient questionnaires led to an increase in completion rates, with 75% of participants completing their yearly surveys, compared to 59% prior to April 2021. A secure patient upload feature for data sharing led to 1,054 participants successfully sharing their mammogram reports with WISDOM between March - June 2021. Previously, mammogram reports were missing for 20% of enrolled participants. This feature has enabled WISDOM to process 300 additional mammogram reports per month. Integration of an auto-launch feature in the participant’s portal in Feb 2021 has led to a 17% increase in participants viewing their screening recommendations in Yr 1. Prior to auto-launch, only 59% (n=6328) of Yr 1 screening recommendations and 61% (n=3681) of genetic testing reports were viewed by participants. Since implementation, the numbers increased to 78% (n=8406) and 85% (n=5160), respectively. Conclusions. Streamlining data to the most essential elements, and minimizing the steps required to share clinical documents, complete questionnaires and open key study notification is essential to improving enrollment rates in virtual, pragmatic trials. Patient-initiated data-sharing tools such as the ability for participants to share documents through secure, online portals is one example of success. Citation Format: Patricia Choy, Tomiyuri Lewis, Stephanie Flores, Leah Sabacan, Halle Thannickal, Steffanie Goodman, Yiwey Shieh, Lisa Madlensky, Jeffrey A. Tice, Elad Ziv, Martin Eklund, Amie Blanco, Barry Tong, Deborah Goodman, Nancy Anderson, Heather Harvey, Steele Fors, Hannah Lui Park, Antonia Petruse, Skye Stewart, Samrrah Raouf, Janet Wernisch, Barbara Koenig, Celia Kaplan, Robert Hiatt, Neil Wenger, Vivian Lee, Diane Heditsian, Susie Brain, Dolores Moorehead, Barbara A Parker, Alexander Borowsky, Hoda Anton-Culver, Arash Naeim, Andrea Kaster, Laura van 't Veer, Andrea Z LaCroix, Olufunmilayo I. Olopade, Deepa Sheth, Agustin Garcia, Rachel Lancaster, Jennifer James, Galen Joseph, Wisdom Study, Athena Breast Health Network Investigators and Advocates, Allison Stover Fiscallini, Laura Esserman. The impact of streamlined processes and patient-directed messaging to improve enrollment in a remote, pragmatic clinical trial [abstract]. In: Proceedings of the 2021 San Antonio Breast Cancer Symposium; 2021 Dec 7-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2022;82(4 Suppl):Abstract nr P5-19-01.
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Bardia, Aditya, James T. Coates, Laura Spring, Sheng Sun, Dejan Juric, Nayana Thimmiah, Andrzej Niemierko, et al. "Abstract 2638: Sacituzumab Govitecan, combination with PARP inhibitor, Talazoparib, in metastatic triple-negative breast cancer (TNBC): Translational investigation." Cancer Research 82, no. 12_Supplement (June 15, 2022): 2638. http://dx.doi.org/10.1158/1538-7445.am2022-2638.
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Abstract Background: Sacituzumab Govitecan (SG), the first antibody-drug conjugate approved for metastatic TNBC (mTNBC), is comprised of SN-38 (active metabolite of irinotecan), a topoisomerase I (TOP1) inhibitor, coupled via a hydrolyzable linker to monoclonal antibody targeting trophoblast cell surface antigen 2 (Trop-2), an antigen overexpressed in mTNBC. Poly (ADP-ribose) polymerase inhibitors (PARPi) block resolution of TOP1 cleavage complexes (TOP1CCs) induced by TOP1 inhibitors, thus unmasking the inability of remaining pathways to repair DNA damage. However, previous clinical trials combining PARPi with standard TOP1 inhibitors (irinotecan, topotecan) were terminated early due to dose-limiting myelosuppression. We evaluated the combination of SG with PARP inhibitor in both pre-clinical models and phase 1b clinical trial. Methods and Results: In pre-clinical models we demonstrated that the targeted antibody-based delivery of SN-38 increased the ratio of tumor-to-normal cell SN-38, resulting in stabilized TOP1CCs, enhanced DNA damage and increased cytotoxicity with the combination, selectively in tumor cells but not normal cells, despite temporal separation of SG and PARPi exposure. To validate the hypothesis, we conducted a phase 1b investigator-initiated clinical trial combining SG with PARPi (talazoparib) in patients with mTNBC (NCT04039230). Inclusion criteria included female patients ≥ 18 years of age with mTNBC (per ASCO/CAP guidelines) and previous treatment with at least one prior therapeutic regimen for mTNBC. Clinical outcomes were assessed by Objective Response Rate per RECIST v1.1. In the phase 1b clinical trial (SG day 18, every 21 days with talazoparib), the staggered schedule with supportive therapy was relatively well-tolerated without DLTs, as predicted by the pre-clinical models. Furthermore, the staggered schedule demonstrated promising clinical activity. Molecular analysis of paired pre-treatment and on-treatment specimens demonstrated γ-H2AX accumulation, confirming pharmacodynamic inhibition with combination therapy. The dose-escalation portion of clinical trial successfully completed enrollment with a recommended phase-2 dose (R2PD) of sequential SG (10 mg/kg on days 1,8) with talazoparib (1 mg on days 15-21), every 21 days. Conclusion: Staggered dosing of SG and PARPi, leveraging the selective drug delivery mechanism of SG to minimize toxicity while maintaining efficacy, was feasible and demonstrated encouraging evidence of clinical activity with objective responses among patients with mTNBC. The translational study highlights how mechanistic insights and innovative scheduling could be utilized to develop promising drug combinations, including previously rejected combinations, for patients with mTNBC. Citation Format: Aditya Bardia, James T. Coates, Laura Spring, Sheng Sun, Dejan Juric, Nayana Thimmiah, Andrzej Niemierko, Phoebe Ryan, Ann Partridge, Jeffrey Peppercorn, Heather Parsons, Seth Wander, Kelsey Pierce, Victoria Attaya, Donna Fitzgerald, Brenda Lormil, Maria Shellock, Aiko Nagayama, Veerle Bossuyt, Bev Moy, Sara Tolaney, Leif Ellisen. Sacituzumab Govitecan, combination with PARP inhibitor, Talazoparib, in metastatic triple-negative breast cancer (TNBC): Translational investigation [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 2638.
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Kashima, Hideaki, Ayumi Honma, Saori Kamimura, Saki Nishimura, Takashi Sano, Shoji Matsumoto, Masako Endo, and Yoshiyuki Fukuba. "Heated Corn Oil and 2,4-Decadienal Suppress Gastric Emptying and Energy Intake in Humans." Nutrients 13, no. 4 (April 15, 2021): 1304. http://dx.doi.org/10.3390/nu13041304.
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Consumption of 2,4-decadienal (2,4-DD) delays gastric emptying (GE) rate in animals. Oil heating produces 2,4-DD and other aldehydes. Here we examined whether heated oil affects GE rate and food intake in humans, and whether it is mediated by 2,4-DD. In the first experiment, 10 healthy volunteers consumed 240-g pumpkin soup with 9.2 g of heated (HO) or non-heated corn oil (CO). Subsequently, 17 participants consumed pumpkin soup containing 3.1 g of either heated corn oil (HO), 1 mg 2,4-DD + non-heated corn oil (2,4-DD), or non-heated corn oil (CO). Sixty minutes following pumpkin soup, cod roe spaghetti was provided, and then energy intake was determined. To evaluate GE rate, 13C breath test (Experiment 1) and ultrasonography (Experiments 1 and 2) were used. The results from the Experiment 1 confirmed that consumption of heated corn oil reduced GE rate. Experiment 2 showed a delayed GE rate in HO and 2,4-DD trials compared with CO trial (p < 0.05). Energy intake was approximately 600–650 kJ lower in HO and 2,4-DD trials compared with CO trial (p < 0.05). These findings suggest that 2,4-DD, either formed by oil heating or added to food, contributes to suppressing GE rate and energy intake.
Dissertations / Theses on the topic "Heather Trials"
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Nitschke, Monika. "Randomised controlled trial investigating the effects of nitrogen dioxide in classrooms on the respiratory health of asthmatic primary school children." Thesis, 2002. http://hdl.handle.net/2440/73201.
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A study to determine the effects of a randomised controlled trial of unflued gas heater replacement on asthma in children. 18 schools using unflued gas heaters in winter were randomly allocated an intervention of heater replacement with either flued gas heaters, or electric, or remained unflued. The main eligibility criteria were doctor-diagnosed asthma with no unflued gas sources at home (a priori sample). The sample was extended to asthmatic children with home gas cooking. Participants kept a daily diary of symptoms for 12 weeks in order to establish symptom rates in the intervention and control groups. Indoor NO₂ was monitored in classrooms and homes during the study period. In the a priori sample, difficulty breathing, chest tightness and asthma attack rates were significantly decreased in the intervention group compared to the control group. In the extended group, symptom rates were not significantly different. Reduced NO₂ levels in classrooms were accompanied by more than a 50% reduction in some asthmatic symptoms in the intervention a priori group.Thesis (Ph.D.) -- University of Adelaide, Dept. of Medicine, 2002
Books on the topic "Heather Trials"
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Makkar, Lali. Whateley Road solar trials: Final report. London (125 Camberwell Rd., SE5 0HB): SLC Energy Group, 1985.
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Daniels, J. L. Heathland management trials at Brindley Heath. Cheltenham: The Commission, 1985.
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James, Alan. Trial of Loki: A Study in Nordic Heathen Morality. Lulu Press, Inc., 2013.
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Anselmi, A. C. M., S. C. E. Gallon, P. Müller, and K. Reinhardt. Populationsgröße, Trichterdichte und Habitatpräferenz der Dünen-Ameisenjungfer Myrmeleon bore (Tjeder, 1941) im Gebiet der Dresdner Heide (Neuroptera). Technische Universität Dresden, 2021. http://dx.doi.org/10.25368/2022.402.
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Following the first record of Myrmeleon bore (Tjeder, 1941) in the Dresden Heath area in 2019 (KURTH 2020, Sächs. Entomol. Z. 10: 71-80), the population size and density of the species was determined. M. bore mainly was found in open, sparsely vegetated, sandy areas with direct sunlight exposure. The area-weighted density of the entire study site (4.05 hectares) was 0.177 larvae/m2. Population size estimates based on random quadrat counts lead to a figure of 4000-7000 individuals - the largest known population of this species. The positive correlation between larval size and pit diameter known for this species from laboratory trials was confirmed at our study site. This correlation may allow researchers to estimate the age structure of wild populations. Given the special responsibility of Germany for the protection of this species and the size of the population, we urge the protection of the site and a prioritisation over other protected species found in the area.
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Church of England. Diocese of Toronto., ed. Fabrications and facts, or, The trials and troubles of a clergyman in the Diocese of Toronto: A romance in real life, in which the Christian acts the heathen, and the heathen puts on the cloak of the Christian, and both conspire to make a holocaust of the clergyman. [S.l: s.n., 1987.
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Alderson, Priscilla. Critical Realism for Health and Illness Research. Policy Press, 2021. http://dx.doi.org/10.1332/policypress/9781447354550.001.0001.
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Critical realism, a toolkit of practical ideas, helps researchers to extend, clarify and validate their work. Critical realism resolves problems and contradictions between quantitative factual research and qualitative interpretive approaches. It draws on their strengths, overcomes their limitations, and helps to connect research to policy and practice. To meet growing demand from researchers and students, the book shows how versatile critical realism can be in research across the life course and around the world, from small studies to large trials. Healthcare, health promotion and heath inequalities are all addressed. This book is based on the course at University College London, first taught by Roy Bhaskar the founder of critical realism, and later convened by the author. The aim is to help readers who are new to critical realism, or are in the fairly early stages, with their research across the whole range of health and illness disciplines and professions. Chapters consider relations between structure and agency, facts and values, and between visible evidence and mainly unseen powerful influences on health and illness. Using clear definitions, diagrams and examples, this book enables readers to understand and apply valuable critical realist concepts to health and illness research.
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Worsnip, Alex. What is (In)coherence? Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198823841.003.0009.
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Philosophers have recently been increasingly attentive to “coherence requirements,” with heated debates about both the content of such requirements and their “normativity” (i.e., whether there is necessarily reason to obey them). Yet there is little work on the metanormative status of coherence requirements. Metaphysically: what is it for two or more mental states to be jointly incoherent, such that they are banned by a coherence requirement? In virtue of what are some putative requirements genuine and others not? Epistemologically: how are we to know which requirements are genuine and which are not? This chapter offers an account that tries to answer these questions. On this account, the incoherence of a set of attitudes is a matter of its being constitutive of the attitudes in question that any agent who holds these attitudes jointly is disposed, when conditions of full transparency are met, to give at least one of them up.
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Montgomery, Alan. Classical Caledonia. Edinburgh University Press, 2020. http://dx.doi.org/10.3366/edinburgh/9781474445641.001.0001.
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Classical Caledonia explores eighteenth-century attitudes towards Scotland’s ancient history and heritage, looking in particular at how Roman Scotland was interpreted at this time. It discusses the research of early modern antiquarians and historians both north and south of the border and looks at how Scotland’s ancient past was often misinterpreted and manipulated in attempts to create a new national identity for a country undergoing rapid and dramatic change. The book uncovers the political, patriotic and intellectual influences which fuelled the heated eighteenth-century debates surrounding the success or failure of the Roman conquests of Scotland, a place sometimes referred to in ancient sources as ‘Caledonia’, and the disagreements regarding the impact of Roman invasion on the evolution of the modern nation. Analysing the period’s historiography, antiquarianism, political propaganda and literature, Classical Caledonia investigates the widespread interest in Scotland’s Roman past during the eighteenth century and reveals the influence of folklore, myth and tradition on the accounts of Scotland’s ancient tribes and their supposed resistance to conquest by the Roman Empire. It also examines the fading interest in the subject of Roman Scotland in the later eighteenth and early nineteenth centuries, as the Scottish Enlightenment and the rise of Romanticism and associated notions of the nation’s origins overtook the desire to establish a classical heritage in the region north of Hadrian’s Wall.
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History of Boxley Parish: The Abbey, Road of Grace, and Abbots; the Clergy; the Church, Monuments and Registers; Including an Account of the Wiat Family, and of the Trial on Penenden Heath In 1076. Creative Media Partners, LLC, 2018.
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Cave-Browne, John. The History of Boxley Parish: The Abbey, Road of Grace, and Abbots; The Clergy; The Church, Monuments and Registers; Including an Account of the Wiat Family, and of the Trial on Penenden Heath in 1076. Franklin Classics Trade Press, 2018.
Find full textBook chapters on the topic "Heather Trials"
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Sutherland, Carl M., Edward T. Krementz, R. Davilene Carter, and James H. Muchmore. "Randomized trials of heated perfusion of extremity melanoma." In Cancer Treatment and Research, 173–76. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-1751-7_10.
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Guida, Michael. "The rambler’s search for the sensuous." In Listening to British Nature, 93–117. Oxford University Press, 2022. http://dx.doi.org/10.1093/oso/9780190085537.003.0005.
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By examining the habits and experiences of walking in the countryside, moors, and mountains a deeply sensual public connection to nature is found in this chapter. Listening is part of this, but so too are touching and other sensory encounters. While rambling on one hand was an escape from the trials of urban and working life, it is argued that the weekend excursions that so many Britons participated in are better thought of as an exchange and balancing out of different sensations available in different places. Having said that, it was encounters with heather, streams, and rock formations that set the pulse racing. Rambling was by no means simply a search for peace and quiet, or for hilltop contemplation, rather walkers relished the accentuation of body rhythms and the stimulation that came from direct interaction with the natural environment.
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Reid, Peter H. "Trial Day Nine." In Every Hill a Burial Place, 186–89. University Press of Kentucky, 2020. http://dx.doi.org/10.5810/kentucky/9780813179988.003.0030.
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On Sunday, the hearing begins with a heated clash after Effiwat accuses Georgiadis of threatening and intimidating potential witnesses. The judge waives off the accusation, and the trial continues. However, before proceeding, he deals with a new volatile issue as several soldiers with submachine guns are stationed at the back of the courtroom. He orders them to leave. At this point, Dr. Gerald Dockeray, the eminent pathologist from Nairobi, begins his testimony, stating that he had performed a postmortem two days after Peppy’s death. Under Georgiadis’s questioning, Dockeray testifies that he did not believe the injuries could have been caused by either the pipe or the stones, as the prosecution alleged. It was more likely that when Peppy pitched forward, fallen, and a stone had caused the injuries.
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Das, Siddhartha, and Sudeepta Pattanayak. "Nanotechnological Approaches in Sustainable Agriculture and Plant Disease Management." In Organic Agriculture. IntechOpen, 2020. http://dx.doi.org/10.5772/intechopen.92463.
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Every year approximately 30–50% of crops suffer with different kinds of biotic stresses. Rapidly growing agrochemical industries and their diverse products make the environment more toxic and simultaneously hazardous for plant heath and soil health. Such types of agrochemicals are toxic, hazardous, carcinogenic, non-eco-friendly. Therefore, this is the ideal time to think about some more effective alternatives against those problems. Nanotechnological approaches bring the alternatives in the form of decreasing toxicity, improving shelf-life, increasing solubility for poorly water-soluble agrochemicals, minimum use with maximum effect, slow leaching efficiency with long-term effect with coupling of eco-friendly naturalistic way. The way of nanoparticle application in agriculture, specifically disease management, is unique, where it can be used singly or by coupling with fungicidal, herbicidal, insecticidal, RNA-interference molecules. Though it has such a positive impact, very few products will be commercially available in our market due to high price of particular products and well-established long field trial efficacy detection among insect, pest-pathogen, and environment. Application of nanomolecules in other progressive fields has been emerging, whereas advancement in agricultural applications needs to be boosted up through skilled knowledge transfer and basic understanding of its fundamental aspect.
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Grewal, Gwenda-lin. "Contradiction." In Thinking of Death in Plato's Euthydemus, 106–27. Oxford University Press, 2022. http://dx.doi.org/10.1093/oso/9780192849571.003.0008.
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One finds in the Euthydemus a plethora of dramatic hints that point to other Platonic dialogues, particularly those that surround Socrates’ trial and execution. Whether these are direct allusions or recurring themes, they heighten the sense that this dialogue is meant to be read as a reflection on the activity of doing philosophy. As Euthydemus and Dionysodorus re-enter the conversation, they claim that to wish Cleinias to become good is to wish for him to become other than he is, which is to wish to destroy (corrupt) him. This makes his lover, Ctesippus, angry. Ctesippus accuses Dionysodorus of falsifying his intent, which leads Euthydemus to ask whether it is possible to speak falsely. If it is not, then it does not seem possible to contradict, to refute, or to be ignorant. And where there is no threat of contradiction, there is no distinction between life and death, and so, no soul. Contradiction, however, comes with a certain heated intensity even or perhaps especially when it is delivered as if it were cold, detached logic. Death may be contradiction’s threat, but by the same turn contradiction is what makes the world come alive. Socrates at least is fearlessly willing to hand himself over to Dionysodorus, as if to Medea, to be boiled alive, provided he will be rejuvenated. The suggestion seems to be that the annihilation of the self that Euthydemus and Dionysodorus offer may be poetically stimulating rather than purely destructive.
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"7 CASE NOTING It is at this point that a case note can be made. The case note has to contain all of the information that enables the case to be used. One of the most important tasks of a law student or, indeed, a legal professional is the ability to read a case and make a usable record of it. The cases that are reported are invariably important as non-important cases remain as court transcripts. The case note must note all of the important issues for the application of precedent, such as: • date of court and formal citation; • hierarchy of court, judges; • facts; • issues before the trial court; • identification of applicable legal rules; • issues, if different before appellate court(s); • procedural history of the case (in what other courts has the matter been heard); • judicial reasoning as to: why those rules applied to those facts in that way. A case note cannot be used if it only records the facts and not the rationale for the outcome as everything in law depends upon the legal reasoning. A case can only be properly used in legal argument when the reasoning of the court is both known and understood. Many students misunderstand the purpose of case noting and think that it is sufficient to have the facts of the case and know the rules concerned. This is a little like having the ingredients for a cake and knowing that, when heated, something changes, but not knowing what to do with the ingredients. It is often not even necessary to rehearse the facts of a case in an argument in which the case is used. What is important is to know points of similarity and difference in facts so that adjustments can be made to the reasoning processes in applying the earlier case to the later situation. If strenuous efforts have been made to understand a law report thoroughly, the following benefits will be achieved: (1) the case note will contain all the ingredients to enable it to be competently applied to any problem question or incorporated into any relevant essay; (2) understanding of the topic and arguing techniques will be increased; (3) competent execution of assessments and examinations (if your analysis of the questions asked is not wrong!)." In Legal Method and Reasoning, 114. Routledge-Cavendish, 2012. http://dx.doi.org/10.4324/9781843145103-87.
Full textConference papers on the topic "Heather Trials"
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Porter, Jason M., Marvin E. Larsen, and John R. Howell. "Discrete Optimization of Radiant Heaters With Simulated Annealing." In ASME 2005 Summer Heat Transfer Conference collocated with the ASME 2005 Pacific Rim Technical Conference and Exhibition on Integration and Packaging of MEMS, NEMS, and Electronic Systems. ASMEDC, 2005. http://dx.doi.org/10.1115/ht2005-72160.
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The simulated annealing algorithm is used to seek optimal radiant heater configurations that provide a desired distribution of incident radiant energy onto a surface. The problem is motivated by a need to create well-understood boundary conditions that simulate fire environments. A bank of halogen lamps irradiates the back of a thin black plate (called a shroud), which simulates the fire environment. For such fire simulations, shroud temperatures routinely exceed 1000 °C and thermal radiation is the dominant mode of heat transfer. The test specimen is then heated by placing it in front of the shroud. The panel, accommodating the radiant heaters (lamps), provides equally spaced slots all of which are powered at the same voltage. Lamp positioning is crucial to obtaining a uniform temperature on the shroud, but determining the best positioning of the lamps experimentally through trial and error has proven difficult. The discrete optimization problem searches possible lamp configurations by simulating adding or removing lamps from the panel. Inverse heat transfer methods have been successfully applied to similar problems. Applying inverse heat transfer methods to this problem, the desired boundary conditions on the shroud are used to solve for the required heater settings. Two boundary conditions are needed: the temperature profile and the heat flux profile on the shroud. The heat flux profile is determined by calculating the radiation heat transfer between the shroud and the test object. However, because the heaters used in the design can only assume discrete positions and are all maintained at the same power level, traditional inverse methods fail. A discrete inverse radiation heat transfer solution method is needed. In this study, a simulated annealing optimization routine is used to determine optimal heater positions given desired boundary conditions on the shroud. Computational characteristics of simulated annealing are presented as well as results of the optimization.
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Nadig, Ranga. "Improvements in the Performance of a Subcooling Zone in a Feedwater Heater With Dual End Plate Design With Water Seal in Between." In ASME 2015 Power Conference collocated with the ASME 2015 9th International Conference on Energy Sustainability, the ASME 2015 13th International Conference on Fuel Cell Science, Engineering and Technology, and the ASME 2015 Nuclear Forum. American Society of Mechanical Engineers, 2015. http://dx.doi.org/10.1115/power2015-49418.
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In a horizontal feedwater heater with a partial length subcooling zone the end plate located at the entrance to the subcooling zone is the only non-welded barrier that prevents the condensing zone steam from entering the subcooling zone. The end plate is usually two or three inches thick and the tube holes in the end plate are drilled to tolerances similar to that of the tubesheet. As the steam from condensing zone tries to enter the subcooling zone it condenses in the tight spaces between the active tube and the tube hole in the end plate forming a liquid barrier that prevents further ingress of steam into the subcooling zone. With usage and wear the gap between the active tube and the tube hole in the end plate increases thereby weakening the liquid barrier. The liquid barrier is completely lost when the tubes are plugged. Steam from condensing zone enters the subcooling zone and disrupts the performance of the subcooling zone, the performance of the feedwater heater and the efficiency of the power plant. This problem is faced by all horizontal feedwater heaters with subcooling zones that are in operation in power plants worldwide. This loss of performance can be eliminated by employing the patent pending Maarky concept of “dual end plate subcooling zone with a water seal”. The “dual end plate subcooling zone with water seal” concept comprises of two end plates separated by a short distance. The gap between the two end plates is filled with condensate thereby forming a triple barrier to ingress of condensing zone steam into the subcooling zone. The performance of the subcooling zone and the longevity of the heater are preserved. This paper discusses the design of subcooling zone in present day feedwater heaters, degradation of performance of subcooling zone and the improvements brought about by the patent pending Maarky concept of “dual end plate subcooling zone with water seal”.
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Kladitis, Paul E., and Victor M. Bright. "Novel Resistive Point Heater for MEMS Remote Solder Self-Assembly." In ASME 2000 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/imece2000-1087.
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Abstract MEMS structures can be assembled using the surface tension of molten solder (solder self-assembly). Until this novel development, solder self-assembly was performed at the wafer or chip level where the whole chip needed to be heated to melt the micro sized solder droplets used to assemble devices. In this paper we present the design, testing, and modeling of a resistive point heater that is used to assemble an individual device on a chip without affecting neighboring devices. The point heater was packaged in 14 and 24 pin ceramic dual inline packages and tested in air, nitrogen, and formic-acid/nitrogen vapor. The lowest power needed to liquify a 63Sn/37Pb, 8 mil diameter equivalent volume solder droplet and assemble a device in formic-acid/nitrogen vapor was found to be 714 mW. The average power, of several trials, required to liquify a solder droplet is 998 mW at 141 mA and 7.08 V. A steady-state heat transfer model predicts 986.4 mW is required to keep the droplet at 181 °C (the observed minimum temperature at which 63Sn/37Pb solder is in liquid state). Growth of pure Sn platey crystals, varified by X-ray flourescence, was noted on the point heater assembly and surroundings during assembly in formic-acid/nitrogen vapor.
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Tom, Alan M., Aleksandar K. Angelov, and John P. Coulter. "An Experimental Investigation of a Micro Injection Molded Mechanical Device." In ASME 2005 International Mechanical Engineering Congress and Exposition. ASMEDC, 2005. http://dx.doi.org/10.1115/imece2005-81968.
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The primary objective of this study, through a scientific experimental investigation, was to determine optimum injection molding processing parameters on semi-crystalline materials HDPE and POM focusing on mechanical properties, obtained thru the use of a nano-indenter, of micro gears being manufactured on non-heated and heated mold bases. A secondary objective was to initiate a similar experimental study using amorphous COC material. Taguchi’s method utilizing an L-9 orthogonal array was used to determine the effects of Tnoz, Tmold, Pinj, Vinj, Ppack, and tpack injection molding processing parameters. A nano-indenter was used to determine investigated mechanical properties on final injection molded parts that included stiffness (S), reduced modulus (Er), and hardness (H). Results showed HDPE, POM and COC, heated mold experiments exhibiting increases in mechanical properties S, Er, and H, on the order of 1.2–4.0 times those of non-heated molding trials. Decreases in optimum molding conditions for Tnoz, Pinj, and Ppack was also observed for heated molding trials. The highest mold temperatures and injection pressures tested did not produce greatest optimum molding conditions. However, largest packing times tested produced optimum molding conditions.
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Abramson, S. B., J. Yang, E. D. Gomperts, C. K. Kasper, and E. J. Fedor. "RELATIVE THERAPEUTIC EFFICACY AND MOLECULAR WEIGHT DISTRIBUTION OF DRY-HEATED AND n-HEPTANE-HEATED PREPARATIONS OF FACTOR VIII." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643920.
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Recent reports by Kemoff et al. (1985) and Gomperts et al. (1987; a multicentered multinational trial) showed that Factor VIII (Antihemophilic Factor, or AHF) “wet” heat-treated in n-hep-tane (Profilate Heat-TreatedR) presented a lower risk of transmitting non-A, non-B hepatitis and HIV than AHF products heated as lyophilized powders. No direct comparison has been reported, however, of the therapeutic efficacy of these products. We compared recovery and half-life in vivo for Profilate Heat-Treated11 with those of the dry-heated products HT ProfilateR and Koate HTR. Two sets of six subjects with severe hemophilia A were infused with either Profilate Heat-TreatedR or a dry-heated AHF in a crossover trial, and blood samples were drawn at times from 10 min to 24 hr. Half-life was determined from a linear regression plot of log (plasma AHF) vs. time from 1 hr to 24 hr. The table gives the mean ± one standard deviation of initial recovery and half-life for each product comparison. Unpaired t-tests showed no significant differences between products. Spearman’s rank analysis showed a high degree of correlation for both the initial recovery and half-life of each product pair.Analysis of molecular weight (MW) distributions of Factor VIII:C polypeptides in several commercial products using the method of Weinstein showed the majority of AHF in all products tested to have MW = 100,000 - 110,000. H.T. FactorateR, which exhibited a substantial amount of the AHF polypeptide whose MW approximates 210,000, is reported by the manufacturer to have a half-life = 11 ± 3.9 hr. We thus conclude that the 210,000 MW form of AHF is not required for therapeutic efficacy.
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Ertürk, Hakan, Ofodike A. Ezekoye, and John R. Howell. "Inverse Design of a Three Dimensional Furnace With Moving Design Environment." In ASME 2001 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2001. http://dx.doi.org/10.1115/imece2001/htd-24327.
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Abstract The inverse design of a three-dimensional furnace that is built to heat an object moving along a conveyor belt of an assembly line is considered. A furnace of this type can be used by the manufacturing industry for applications such as curing of paint, annealing or manufacturing through chemical deposition. The object that is to be heated moves along the furnace as it is heated following a specified temperature history while the spatial temperature distribution is kept isothermal through the whole process. The temperature distribution of the heaters of the furnace should be changed as the object moves so that the specified temperature history can be satisfied. The design problem is a transient design problem where a series of inverse solutions is utilized. The process furnace considered is in the shape of a rectangular tunnel where the heaters are located at top and the design object moves at the bottom. The inverse formulation of such a system is advantageous over a traditional trial-and-error solution where an iterative solution is required for every position as the object moves. The inverse formulation of the design problem involves ill-posed Fredholm equation of the first kind and the use of a regularized solver rather than an ordinary one such as Gauss-Seidel or Gauss elimination is essential. The radiative transfer is formulated utilizing the Monte Carlo method that enables including further realistic characteristics like specularly reflecting walls.
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Glasare, Karin B., Eva K. Olsson, Michael R. von Spakovsky, and Gunnar Svedberg. "Analysis of Kalina Cycle Designs With Modifications Including a Distillation Column." In ASME 1993 International Gas Turbine and Aeroengine Congress and Exposition. American Society of Mechanical Engineers, 1993. http://dx.doi.org/10.1115/93-gt-156.
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It has been shown in a number of studies that the Kalina cycle can have considerably higher efficiencies than the Rankine cycle. An especially advantageous application is as a bottoming cycle to a gas turbine. In this paper a gas turbine topping cycle has been assumed. Three different configurations of the Kalina bottoming cycle have been examined and compared. One is an original cycle (El-Sayed and Tribus, 1985) with a flash separator. In another configuration, a second feedwater heater is added and in a third a distillation column instead of a flash separator is used. The stages of the column are heated by exchanging heat with two different streams in the Kalina distillation condensation subsystem. For each configuration, the different compositions in the cycle have been varied. The First Law efficiency and the exergetic efficiency have been calculated as well as the rate of exergy loss in each unit. The results show that the cases with the best performance of each of the three configurations differ very little in efficiency. The original cycle has the highest efficiency for the conditions studied.
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Dinh, Thien X., and Yoshifumi Ogami. "A Three-Axis Thermal Accelerometer." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-63420.
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The paper presents the numerical design and performance of a triple-axis thermal accelerometer. In a typical thermal accelerometer, a heater is suspended at the center and sensing elements are located around the heater on the opening side of a cavity. Consequently, the sensitivity of the vertical axis measurement is very low in comparison with the horizontal axes measurements and the cross-sensitivity between these measurements is very high. In our new design, the heater is formed a wide ring and the sensing elements are located both inside and outside of the heater ring with a small elevation from the heater plane. The obtained results show that the sensitivity of the vertical axis measurement attains to the order of the horizontal axes measurements. The cross-sensitivities among three axes are less than 4%. For instance, at the supplied power of 15mW to the heating resistor, the sensitivity of the accelerometer is 0.12°C/g in the vertical axis and 0.25°C/g in the horizontal axes.
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Blésin, Terence, Anat Siddharth, Hao Tian, Rui Ning Wang, Alaina Attanasio, Junqiu Liu, Sunil A. Bhave, and Tobias J. Kippenberg. "Microwave-optical transduction using high overtone bulk acoustic resonances." In CLEO: Applications and Technology. Washington, D.C.: Optica Publishing Group, 2022. http://dx.doi.org/10.1364/cleo_at.2022.jth3b.26.
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We demonstrate efficient microwave-optical frequency conversion using a released HBAR-on-photonic damascene platform. Thermal tuning of coupled optical ring cavities with integrated heaters allows to operate in the triply resonant transduction scheme.
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Le-Naour, Frederic, Antoine Marret, Kenny MacLeod, Romain Vivet, and Ida Margaretha Aglen. "Electrical & Optical Double Barrier Qualification and Implementation on FENJA Electrically Trace Heated Pipe-in-Pipe Project." In Offshore Technology Conference. OTC, 2021. http://dx.doi.org/10.4043/31214-ms.
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Abstract This paper provides an overview of the work completed to design, qualify, manufacture and integrate electrical and optical double barrier penetrators with the Electrically Trace Heated Pipe-in-Pipe (ETH-PiP) as part of the Neptune Energy Fenja Development Project. Typical subsea penetrator systems in the oil and gas industry, such as pumps, compressors and X-trees are designed to be retrievable, to enable periodic refurbishment as well as providing the option for replacement, if required. However, the ETH-PiP architecture makes retrieval of system components complicated and uneconomical. Both the electrical and optical dual barrier penetrator system designs have to comply with a set of ETH-PiP specific criteria, such as to be maintenance free over a 25 years service life, prevent water ingress to the pipeline, provide pressure containment for operational media (in an unlikely scenario where the inner pipe bursts) and guarantee minimum footprint to allow an optimum integration onto the Pipeline End Termination (PLET) structure. In addition, the electrical system has to comply with a medium voltage rating (i.e. 5.0/8.7kV) to ensure a wide range of possible ETH-PiP architectures. The optical system has to maintain insertion loss below 0.5dB and a back reflection below -45dB to comply with the stringent requirements of distributed temperature monitoring sensor system over long distances. The qualification program of the electrical dual barrier penetrator system was performed in accordance with IEC 60502-4 and SEPS-SP-1001. A tailor made sequence had to be developed for the optical system, based on guidance from SEAFOM-TSD-01, considering that the system partly falls outside the associated standard application. The electrical dual barrier penetrator system qualification sequence was developed in two phases; firstly, the electrical transition contacts in the feedthrough chamber were qualified in accordance with IEC 60502-4 and secondly, four electrical double barrier penetrator prototypes were manufactured to allow the completion of the qualification sequence defined as per SEPS-SP-1001. The optical dual barrier penetrator system qualification employed the manufacturing of three prototypes to execute the pre-defined qualification sequence. Following the individual qualification of the electrical and optical dual barrier penetrator systems, subsequent welding and full-scale assembly trials were performed to ensure that the maximum allowable temperatures within the penetrators would not be exceeded during welding to the PLET, and to proof test the assembly procedure. Electrical verification testing was also undertaken during these trials to verify that the integrity of the penetrators had been maintained during the assembly and that the PLET arrangement did not give rise to any electrical stresses that could result in excessive deterioration of the penetrators. Integration of the four electrical and two optical dual barrier penetrator systems to the project PLET was completed in Q1 2020, with the actual subsea installation of the first ETH-PiP section including the PLET in Q3 2020.
Reports on the topic "Heather Trials"
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Yaroslav Chudnovsky and Aleksandr Kozlov. Development and Field Trial of Dimpled-Tube Technology for Chemical Industry Process Heaters. Office of Scientific and Technical Information (OSTI), October 2006. http://dx.doi.org/10.2172/894062.
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Poverenov, Elena, Tara McHugh, and Victor Rodov. Waste to Worth: Active antimicrobial and health-beneficial food coating from byproducts of mushroom industry. United States Department of Agriculture, January 2014. http://dx.doi.org/10.32747/2014.7600015.bard.
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Background. In this proposal we suggest developing a common solution for three seemingly unrelated acute problems: (1) improving sustainability of fast-growing mushroom industry producing worldwide millions of tons of underutilized leftovers; (2) alleviating the epidemic of vitamin D deficiency adversely affecting the public health in both countries and in other regions; (3) reducing spoilage of perishable fruit and vegetable products leading to food wastage. Based on our previous experience we propose utilizing appropriately processed mushroom byproducts as a source of two valuable bioactive materials: antimicrobial and wholesome polysaccharide chitosan and health-strengthening nutrient ergocalciferol⁽ᵛⁱᵗᵃᵐⁱⁿ ᴰ2⁾. ᴬᵈᵈⁱᵗⁱᵒⁿᵃˡ ᵇᵉⁿᵉᶠⁱᵗ ᵒᶠ ᵗʰᵉˢᵉ ᵐᵃᵗᵉʳⁱᵃˡˢ ⁱˢ ᵗʰᵉⁱʳ ᵒʳⁱᵍⁱⁿ ᶠʳᵒᵐ ⁿᵒⁿ⁻ᵃⁿⁱᵐᵃˡ ᶠᵒᵒᵈ⁻ᵍʳᵃᵈᵉ source. We proposed using chitosan and vitamin D as ingredients in active edible coatings on two model foods: highly perishable fresh-cut melon and less perishable health bars. Objectives and work program. The general aim of the project is improving storability, safety and health value of foods by developing and applying a novel active edible coating based on utilization of mushroom industry leftovers. The work plan includes the following tasks: (a) optimizing the UV-B treatment of mushroom leftover stalks to enrich them with vitamin D without compromising chitosan quality - Done; (b) developing effective extraction procedures to yield chitosan and vitamin D from the stalks - Done; (c) utilizing LbL approach to prepare fungal chitosan-based edible coatings with optimal properties - Done; (d) enrichment of the coating matrix with fungal vitamin D utilizing molecular encapsulation and nano-encapsulation approaches - Done, it was found that no encapsulation methods are needed to enrich chitosan matrix with vitamin D; (e) testing the performance of the coating for controlling spoilage of fresh cut melons - Done; (f) testing the performance of the coating for nutritional enhancement and quality preservation of heath bars - Done. Achievements. In this study numerous results were achieved. Mushroom waste, leftover stalks, was treated ʷⁱᵗʰ ᵁⱽ⁻ᴮ ˡⁱᵍʰᵗ ᵃⁿᵈ ᵗʳᵉᵃᵗᵐᵉⁿᵗ ⁱⁿᵈᵘᶜᵉˢ ᵃ ᵛᵉʳʸ ʰⁱᵍʰ ᵃᶜᶜᵘᵐᵘˡᵃᵗⁱᵒⁿ ᵒᶠ ᵛⁱᵗᵃᵐⁱⁿ ᴰ2, ᶠᵃʳ ᵉˣᶜᵉᵉᵈⁱⁿᵍ any other dietary vitamin D source. The straightforward vitamin D extraction procedure and ᵃ ˢⁱᵐᵖˡⁱᶠⁱᵉᵈ ᵃⁿᵃˡʸᵗⁱᶜᵃˡ ᵖʳᵒᵗᵒᶜᵒˡ ᶠᵒʳ ᵗⁱᵐᵉ⁻ᵉᶠᶠⁱᶜⁱᵉⁿᵗ ᵈᵉᵗᵉʳᵐⁱⁿᵃᵗⁱᵒⁿ ᵒᶠ ᵗʰᵉ ᵛⁱᵗᵃᵐⁱⁿ ᴰ2 ᶜᵒⁿᵗᵉⁿᵗ suitable for routine product quality control were developed. Concerning the fungal chitosan extraction, new freeze-thawing protocol was developed, tested on three different mushroom sources and compared to the classic protocol. The new protocol resulted in up to 2-fold increase in the obtained chitosan yield, up to 3-fold increase in its deacetylation degree, high whitening index and good antimicrobial activity. The fungal chitosan films enriched with Vitamin D were prepared and compared to the films based on animal origin chitosan demonstrating similar density, porosity and water vapor permeability. Layer-by-layer chitosan-alginate electrostatic deposition was used to coat fruit bars. The coatings helped to preserve the quality and increase the shelf-life of fruit bars, delaying degradation of ascorbic acid and antioxidant capacity loss as well as reducing bar softening. Microbiological analyses also showed a delay in yeast and fungal growth when compared with single layer coatings of fungal or animal chitosan or alginate. Edible coatings were also applied on fresh-cut melons and provided significant improvement of physiological quality (firmness, weight ˡᵒˢˢ⁾, ᵐⁱᶜʳᵒᵇⁱᵃˡ ˢᵃᶠᵉᵗʸ ⁽ᵇᵃᶜᵗᵉʳⁱᵃ, ᵐᵒˡᵈ, ʸᵉᵃˢᵗ⁾, ⁿᵒʳᵐᵃˡ ʳᵉˢᵖⁱʳᵃᵗⁱᵒⁿ ᵖʳᵒᶜᵉˢˢ ⁽Cᴼ2, ᴼ²⁾ ᵃⁿᵈ ᵈⁱᵈ not cause off-flavor (EtOH). It was also found that the performance of edible coating from fungal stalk leftovers does not concede to the chitosan coatings sourced from animal or good quality mushrooms. Implications. The proposal helped attaining triple benefit: valorization of mushroom industry byproducts; improving public health by fortification of food products with vitamin D from natural non-animal source; and reducing food wastage by using shelf- life-extending antimicrobial edible coatings. New observations with scientific impact were found. The program resulted in 5 research papers. Several effective and straightforward procedures that can be adopted by mushroom growers and food industries were developed. BARD Report - Project 4784