Academic literature on the topic 'Heart valve prosthesis'

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Journal articles on the topic "Heart valve prosthesis"

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Briffa, Norman Paul. "Results of mechanical versus tissue AVR: caution in young patients with tissue AVR." Heart 105, Suppl 2 (March 2019): s34—s37. http://dx.doi.org/10.1136/heartjnl-2018-313516.

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The first aortic valve prosthesis, implanted more than 50 years ago, was a mechanical prosthesis (ball-and-cage design). Over the ensuing decades, tissue prostheses and new mechanical designs were introduced to mitigate the need for anticoagulation with its associated side effects. Tissue and mechanical heart valve prostheses were compared in two head-to-head randomised control trials. Both of these confirmed that mechanical prostheses were durable but patients suffered anticoagulant-related bleeds. Patients who received a tissue prosthesis were more likely to suffer prosthetic dysfunction and require reoperation. This trend was stronger in younger patients. Since the publication of those two trials, several large retrospective studies using data from meta-analyses of published papers or registries have failed to show a survival advantage of either prostheses when implanted in the aortic position in younger patients. This equipoise has been reflected in the heart valve disease guidelines published by European and US societies. In recent years, the primacy of patient choice, the rapid increase in life expectancy of populations, the increased incidence of atrial fibrillation with requirement for anticoagulation, the advent of transcatheter techniques to treat degenerating tissue valves as well as advances in anticoagulant therapy and in new tissue and to a lesser extent mechanical prosthetic design continue to influence choice of aortic valve prosthesis in younger patients undergoing aortic valve replacement.
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Ingimarsdóttir, I. J., L. Hellgren Johansson, and F. A. Flachskampf. "Preoperative aortic annulus size assessment by transthoracic echocardiography compared to the size of surgically implanted aortic prostheses." Echo Research and Practice 6, no. 2 (June 2019): 37–41. http://dx.doi.org/10.1530/erp-19-0010.

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Objectives The aortic annulus diameter measured by transthoracic echocardiography yields lower values than by computed tomography, and echo-based selection of transcatheter aortic valve prosthesis size has been implied to result in more frequent paravalvular leakage. We investigated the relation of preoperative annulus diameter by echo with the ring size of the aortic prosthesis chosen by direct assessment during open-heart aortic valve replacement. Methods Preoperative annulus diameter by echo (from parasternal long-axis cross-sections of the left ventricular outflow tract and aortic valve) and implanted prosthetic diameter (tissue annulus diameter, determined intraoperatively using a sizing instrument) were compared retrospectively in 285 consecutive patients undergoing open-heart aortic valve replacement. Results A total of 285 prostheses (240 biologic and 45 mechanical) were implanted, with prosthetic diameter ranging between 19 and 27 mm. There was a significant linear correlation (P < 0.0001) with r = 0.51, between preoperative annulus diameter by echo (mean 21.8 ± 2.8 mm) and prosthetic diameter (22.9 ± 1.7 mm). Preoperative annulus diameter of patients receiving prostheses no. 21, 23 and 25 mm aortic prostheses (the most frequent prosthesis sizes) were significantly different (P < 0.001) from each other. On average, preoperative annulus diameter by echo underestimated prosthetic diameter by a bias of 1.07 mm. Conclusion Our data confirm that preoperative echo assessment of the aortic valve may slightly underestimates the optimal surgical prosthesis diameter for the aortic valve annulus.
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Perekopskaya, Veronika S., Nataliya A. Morova, and Valeriy N. Tsekhanovich. "The structural-geometric and functional parameters of the heart in patients after mitral prosthetics with new full-flow valves in the long-term period." CardioSomatics 13, no. 1 (July 29, 2022): 4–10. http://dx.doi.org/10.17816/22217185.2022.1.201469.

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Aim. To compare the results of mitral valve replacement with the full-flow mechanical valve MedInzh-ST and the classical prosthesis MedInzh-2, to learn the structural and functional parameters of the heart depending from the prosthesis in the long-tern period. Material and methods. From 2015 to February 2020 years an the basis of the cardio-surgical department of the Regional clinical Hospital 116 patients, in order to correct defects, were underwent mitral prosthetics with MedInzh valves. Of these 55 patients received a new full-flow valve MedInzh-ST. 61 patients a classical MedInzh-2. Before surgery and in the long-term period all patients were underwent transthoracic echocardiography with using expert-class devices. In the long-tern postoperative period 34 patients were underwent echocardiographic research after implantation full-flow valves and 40 patients after prosthetics of classical prosthesis. Results. The choice of the prosthesis model did not affect the incidence of postoperative complications and the rate of hospital mortality. In all cause of death is not associated with impaired function of the prosthesis. All patients before the discharge from hospital were fixed the positive effect from surgical treatment. In the long-term postoperative period between patients after implantation of full-flow valves, the cases of prosthetic platelets were not registered. One patient was diagnosed with prosthetic thrombosis after implantation of a classical prosthesis, which required further reprosthetics. There were no signs of prosthetic endocarditis and paraprosthetic fistula in both groups. There were no significant differences in the structural and geometric parameters of the heart in all patients. Conclusion. Analysis of the functional characteristics of the new full-flow valve MedInzh-ST in the long-term period allows us to conclude that the new valve model meets modern requirements for efficiency and safety.
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Schröter, Filip, Ralf-Uwe Kühnel, Martin Hartrumpf, Roya Ostovar, and Johannes Maximilian Albes. "Progress on a Novel, 3D-Printable Heart Valve Prosthesis." Polymers 15, no. 22 (November 15, 2023): 4413. http://dx.doi.org/10.3390/polym15224413.

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(1) Background: Polymeric heart valves are prostheses constructed out of flexible, synthetic materials to combine the advantageous hemodynamics of biological valves with the longevity of mechanical valves. This idea from the early days of heart valve prosthetics has experienced a renaissance in recent years due to advances in polymer science. Here, we present progress on a novel, 3D-printable aortic valve prosthesis, the TIPI valve, removing the foldable metal leaflet restrictor structure in its center. Our aim is to create a competitive alternative to current valve prostheses made from flexible polymers. (2) Methods: Three-dimensional (3D) prototypes were designed and subsequently printed in silicone. Hemodynamic performance was measured with an HKP 2.0 hemodynamic testing device using an aortic valve bioprosthesis (BP), a mechanical prosthesis (MP), and the previously published prototype (TIPI 2.2) as benchmarks. (3) Results: The latest prototype (TIPI 3.4) showed improved performance in terms of regurgitation fraction (TIPI 3.4: 15.2 ± 3.7%, TIPI 2.2: 36.6 ± 5.0%, BP: 8.8 ± 0.3%, MP: 13.2 ± 0.7%), systolic pressure gradient (TIPI 3.4: 11.0 ± 2.7 mmHg, TIPI 2.2: 12.8 ± 2.2 mmHg, BP: 8.2 ± 0.9 mmHg, MP: 10.5 ± 0.6 mmHg), and effective orifice area (EOA, TIPI 3.4: 1.39 cm2, TIPI 2.2: 1.28 cm2, BP: 1.58 cm2, MP: 1.38 cm2), which was equivalent to currently used aortic valve prostheses. (4) Conclusions: Removal of the central restrictor structure alleviated previous concerns about its potential thrombogenicity and significantly increased the area of unobstructed opening. The prototypes showed unidirectional leaflet movement and very promising performance characteristics within our testing setup. The resulting simplicity of the shape compared to other approaches for polymeric heart valves could be suitable not only for 3D printing, but also for fast and easy mass production using molds and modern, highly biocompatible polymers.
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Bloomfield, P. "Choice of heart valve prosthesis." Heart 87, no. 6 (June 1, 2002): 583–89. http://dx.doi.org/10.1136/heart.87.6.583.

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Nazarov, V. M., S. I. Zheleznev, A. V. Bogachev-prokofev, A. V. Afanasev, I. I. Demin, and D. A. Astapov. "Comparative studies of modern mechanical valve prosthesis (review)." Patologiya krovoobrashcheniya i kardiokhirurgiya 17, no. 2 (October 10, 2015): 79. http://dx.doi.org/10.21688/1681-3472-2013-2-79-84.

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More than 50 years have passed since the first successful heart valve replacement. Since then, many types of mechanical prostheses have been introduced. The prosthesis choice for the replacement of an affected valve is a major concern in valvular surgery. The introduction of a new heart valve prosthesis requires accurate data collection and data processing for a long follow-up period. In present article we sought to compare modern commercial available bileaflet foreign mechanical valve prosthesis for their long follow-up with Russian mechanical valve for aortic and mitral valve replacement.
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Gramatikov, D. G., V. S. Litus, V. K. Noginov, K. E. Budanov, and K. V. Samko. "Replacement of aortic valve flaps with an autopericardium using the S. Ozaki technique." Grekov's Bulletin of Surgery 181, no. 3 (July 4, 2022): 81–84. http://dx.doi.org/10.24884/0042-4625-2022-181-3-81-84.

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Classical aortic valve replacement is often fraught with negative outcomes for patients. When replacing the aortic valve with a mechanical valve prosthesis, the patient is associated for life with the use of indirect anticoagulants, which often leads to hemorrhagic and thrombotic complications. In the case of replacement of the aortic valve with a biological prosthesis, a fairly frequent complication is early calcification and, consequently, a high frequency of dysfunctions of the biological prosthesis. In addition, mechanical and biological prosthetics of heart valves are quite expensive, which creates a serious economic load on the healthcare institution. But in the last decade, the technique of neocuspidization of the aortic valve with autopericardial flaps has been introduced into wide cardiac surgical practice, which is a clear alternative to prosthetics of heart valves.
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Klyshnikov, K. Yu, E. A. Ovcharenko, A. N. Stasev, T. V. Glushkova, Yu A. Kudryavtseva, and L. S. Barbarash. "Experimental substantiation of the design of a prosthetic heart valve for «valve-in-valve» implantation." Russian Journal of Transplantology and Artificial Organs 19, no. 2 (June 23, 2017): 69–77. http://dx.doi.org/10.15825/1995-1191-2017-2-69-77.

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The aim of the study was to perform a series of in vitro tests of a prototype of the developing heart valve prosthesis to evaluate its functional characteristics. Materials and methods. In this work we have used the frames and full prototypes of the prosthesis, consisting of a stent-like stainless steel support frame with mounted biological leaflets and cover. The authors evaluated the calculated and experimental forces necessary for the displacement of the sutureless implanted prosthesis using the test machine under uniaxial tension. The risk of defects and damages to the supporting framework as a result of implantation was evaluated by scanning electron microscopy. The hydrodynamic characteristics of the prosthesis were investigated under physiological conditions and «valvein-valve» implantation. Evaluation of the ergonomics and applicability of the proposed construction on the cadaver heart model of cattle was carried out. Results. As a result of the forces assessment, it was found that the force required to shear the prosthesis was 3.12 ± 0.37 N, while the calculated value was 1.7 N, which is significantly lower than the obtained value. The comparison of the images obtained with small and large magnifications demonstrated the absence of critical surface defects. Additional analysis under the super-large magnifications also did not reveal problem areas. During the hydrodynamic study, it was shown that the average transplant gradient increased slightly from 2.8–3.4 to 3.2–4.5 mm Hg for the initial prosthesis and the «valve-in-valve» complex, respectively. The decrease of the effective orifice area was 6–9% relative to the initial one. Evaluation of the implantation technique demonstrated the consistency of the approach: the use of the developed holder in combination with the balloon implantation system made it possible to position the prosthesis throughout the procedure. Conclusion. The series of tests demonstrates the consistency of the developed design, intended for the replacement of a failed prosthetic valve of the heart with the «valve-in-valve» implantation.
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Wysokinska, Ewa M., Katherine M. Duello, Dong Chen, and Joseph L. Blackshear. "Evaluation of Prosthetic Valve Function by Platelet Function Analysis and Von Willebrand Factor Indices." Blood 120, no. 21 (November 16, 2012): 1128. http://dx.doi.org/10.1182/blood.v120.21.1128.1128.

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Abstract Abstract 1128 Background Dysfunctional or mismatched prosthetic heart valves can results in high shear stress related von Willebrand factor (VWF) impairment, and clinical bleeding. This mechanism is similar to that seen in aortic stenosis patients, where gastrointestinal bleeding related to VWF multimer loss is well described (Heyde syndrome). In this study, we compared the results of VWF testing of patients with normally functioning cardiac valve prostheses, dysfunctional prosthetic valves, severe native aortic stenosis, and normal controls. Methods A total of 75 patients, 31 female and 44 male with a median age of 79.5 years were recruited to this study. Thirty patients had severe aortic stenosis (mean gradient > 40 mm Hg); 39 patients had normally functioning prosthetic valves, 21 aortic (AVR) and 18 mitral valves (MVR); and 6 patients had with dysfunctional valves (4 aortic and 2 mitral). Whole blood and plasma samples were drawn from patients and tested for platelet function analyzer-100 collagen ADP closure time (PFA-CADP), VWF antigen (VWF:Ag), VWF activity by latex immunoassay (VWF:Ltx), VWF multimer analysis and VWF multimer densitometry ratio of large vs medium to low molecular weight multimers (>15 mers/2–15 mers). Results The 6 dysfunctional prosthetic valve patients included patient-prosthesis mismatch (2) and (one each), thrombosed mechanical aortic prosthesis, torn biological aortic prosthesis, severe tissue mitral prosthetic regurgitation, and post-mitral valve repair severe mitral regurgitation. Four of six patients had clinically significant bleeding. Most aortic stenosis and all 6 prosthetic dysfunction patients had abnormal VWF multimers which is rare in normally functioning prostheses and completely absent in normal donors. VWF:Ltx/Ag was lower in AS and MVR than normal. VWF:Ltx/Ag ratio, VWF:multimer ratio and PFA-CADP were all significantly abnormal in patients with dysfunctional prosthetic valve. VWF:multimer ratios in normally functioning prostheses tended to be intermediate between normals and than those of patients with severe AS or prosthetic valve dysfunction (Table). Conclusions VWF testing including quantitative von Willebrand multimer analysis and PFA-CADP reliably separate dysfunctional from normally functioning cardiac prostheses, and should be considered in the evaluation of patients with cardiac prostheses, especially those who have clinically significant bleeding. Disclosures: No relevant conflicts of interest to declare.
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Klyshnikov, K. Yu, E. A. Ovcharenko, Yu A. Kudryavtseva, and L. S. Barbarash. "Hydrodynamic performance of a novel suturelessprosthetic aortic valve." Russian Journal of Transplantology and Artificial Organs 22, no. 2 (July 12, 2020): 117–24. http://dx.doi.org/10.15825/1995-1191-2020-2-117-124.

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The aim of the study was an in vitro hydrodynamic study of the developed prosthetic heart valve of the second generation, designed to carry out an implantation using «valve-in-valve» method. Material and methods. Prototypes of the developed prosthesis were studied under simulated physiological conditions of the heart using a Vivitro Labs pulse duplicator (Canada) in a comparative aspect with «UniLine» clinical commercial aortic valve bioprosthesis (Russia). Samples were tested by simulating sutureless implantation procedure. Results. The developed valves showed satisfactory hydrodynamic characteristics – for all cases of «implantation» from the position of the average trans-prosthetic gradient (6.1–11.1 mm Hg) and the effective orifice area (1.60–1.81 cm2 ). The analysis of the regurgitation fraction allowed us to determine the optimal sizes for implantation using «valvein-valve» method, which subsequently will form the basis of sizing guidelines for size selection. A qualitative analysis of the leaflet’s work demonstrated the presence of slight asymmetry for a number of prostheses – in case of mismatch of sizes when simulating «valve-in-valve» procedure. Conclusion. The tests demonstrate the viability of the developed design from the standpoint of hydrodynamic efficiency and determines the basic rules of selecting a prosthesis for reimplantation relative to the primary valve.
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Dissertations / Theses on the topic "Heart valve prosthesis"

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Dellgren, Göran. "Aortic valve replacement with stentless bioprostheses : prospective long-term studies of the Biocor and the Toronto SPV /." Stockholm : Karolinska institutet, 2002. http://diss.kib.ki.se/2002/91-7349-152-7.

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Damen, Bas Stefaan, and bsdamen@hotmail com. "Design, Development, and Optimisation of a Culture Vessel System for Tissue Engineering Applications." Swinburne University of Technology. n/a, 2003. http://adt.lib.swin.edu.au./public/adt-VSWT20040512.125051.

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A Tissue Engineering (TE) approach to heart valve replacement has the aim of producing an implant that is identical to healthy tissue in morphology, function and immune recognition. The aim is to harvest tissue from a patient, establish cells in culture from this tissue and then use these cells to grow a new tissue in a desired shape for the implant. The scaffold material that supports the growth of cells into a desired shape may be composed of a biodegradable polymer that degrades over time, so that the final engineered implant is composed entirely of living tissue. The approach used at Swinburne University was to induce the desired mechanical and functional properties of tissue and is to be developed in an environment subjected to flow stresses that mimicked the haemodynamic forces that natural tissue experiences. The full attainment of natural biomechanical and morphological properties of a TE structure has not as yet been demonstrated. In this thesis a review of Tissue Engineering of Heart Valves (TEHVs) is presented followed by an assessment of biocompatible materials currently used for TEHVs. The thrust of the work was the design and development of a Bioreactor (BR) system, capable of simulating the corresponding haemodynamic forces in vitro so that long-term cultivation of TEHVs and/or other structures can be mimicked. A full description of the developed BR and the verification of its functionality under various physiological conditions using Laser Doppler Anemometry (LDA) are given. An analysis of the fluid flow and shear stress forces in and around a heart valve scaffold is also provided. Finally, preliminary results related to a fabricated aortic TEHV-scaffold and the developed cell culture systems are presented and discussed. Attempts to establish viable cell lines from ovine cardiac tissue are also reported.
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Bishop, Winona F. "Hydrodynamic performance of mechanical and biological prosthetic heart valves." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/29461.

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One of the major achievements in cardiac surgery over the past 30 years has been the ability to replace severely diseased heart valves with prosthetic ones. The option of using prosthetic heart valves for the treatment of valvular diseases has improved and prolonged many lives. This is reflected in around 120,000 heart valve replacement operations carried out every year in North America alone to correct the cardiovascular problems of stenosis, insufficiency, regurgitation, etc. The development of artificial heart valves depends on reliable knowledge of the hemodynamic performance and physiology of the cardiovascular system in addition to a sound understanding, at the fundamental level, of the associated fluid mechanics. It is evident from the literature review that noninvasive measurements in a confined area of complex transient geometry, providing critical information relating to valve performance, are indeed scarce. This thesis presents results of an extensive test program aimed at measuring turbulence stresses, steady and transient velocity profiles and their decay downstream of the mitral valve. Three mechanical tilting disc-type heart valves (Björk-Shiley convexo- concave, Björk-Shiley monostrut, and Bicer-Val) and two biological tissue valves (Hancock II and Carpentier-Edwards supraannular) are studied. The investigation was carried out using a sophisticated and versatile cardiac simulator in conjunction with a highly sensitive, noninvasive, two-component three-beam laser doppler anemometer system. The study covers both the steady (valve fully open) and pulsatile (resting heart rate) flow conditions. The continuous monitoring of the parametric time histories revealed useful details of the complex flow as well as helped establish location and timing of the peak parameter values. In addition, orientation experiments are conducted on the mechanical valves in an attempt to reduce stresses by altering the position of the major orifice. The experiments suggest correlation between high stresses and orientation. Based on the the data, the following general conclusions can be made: (i) Hemodynamic test results should be presented in nondimensional form to render them independent of test facilities, flow velocities, size of models, etc. This would facilitate comparison of results by different investigators, using different facilities and test conditions. (ii) The valves tested showed very disturbed flow fields which generated high turbulent stresses presenting a possibility of thromboembolism and, perhaps, haemolysis. (iii) Implantation orientation of the valve significantly affect the mechanical prostheses flow field. The single vortex formation in the posterior orientation results in a reduction in stresses compared to the anterior configuration. (iv) The present results together with the earlier information on pressure drop and regurgitation provide a comprehensive and organized picture of the valve performance. (v) The information is fundamental to the improvement in valve design, and development of guidelines for test methodology and acceptable performance criteria for marketing of the valves.
Applied Science, Faculty of
Mechanical Engineering, Department of
Graduate
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Jones, Mark I. "Haemocompatibility and charactersation of candidate coatings for heart valve prosthesis." Thesis, University of Nottingham, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.301695.

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Prosthetic cardiac valve surgery is a well-established technique, but the search continues for engineering materials with sup..e rior mechanical characteristics in order to extend the service life of the implant. The introduction of pyrolytic carbon was seen as a breakthrough in the development of wear resistant, non-thrombogenic materials for such applications. However, thrombo-embolic phenomena and the need for anticoagulation treatment following valve insertion remain the main problems associated with artificial materials in this application. The work carried out in this research has studied the haemocompatibility of a commercially available, wear resistant TiffiN/TiCfDLC multilayer structure, and a second TiN coating deposited by RF reactive sputtering of a titanium target in a ArIN2 environment, as candidate materials for a heart valve prosthesis. The structure of the RF deposited tiN coating was assessed as a function of deposition conditions, and was seen to develop a particular preferred crystallographic orientation. The nature of this texture was influenced by the condition of the underlying substrate. The effect of substrate condition on the biocompatibility of the tiN coating was studied by assessment of fibroblast attachment and spreading, and by haemolytic analysis of released haemoglobin. The results showed that the initial attachment and orientation of fibroblast cells was influenced by the substrate condition, but no influence on the degree of spreading and haemolytic nature was observed. Characterisation of the TiN coating and the components of the multilayer structure was carried out by Atomic Force Microscopy (AFM), X-ray Photoelectron Spectroscopy (XPS), stylus profilometry and contact angle measurement. Haemocompatibility was studied by the interaction of the surfaces with plasma proteins, blood platelets and red blood ceUs. Cytotoxicity was studied using the MTT test. The degree of platelet activation on the surfaces correlated with their surface energy. The greatest degree of platelet spreading was observed on the more hydrophilic coatings. The lack of platelet activation seen on the DLC coating is attributed to its smooth surface and hydrophobic nature, resulting in higher levels of adsorption of anticoagulation proteins. The RF sputtered TiN coating caused significant levels of haemolysis and fibroblast cell death. None of the components of the multilayer structure caused such effects, although thrombus formation was observed to a degree on the Ti, TiN and TiC components of this structure. The toxic nature of the RF deposited TiN coating was not attributed to surface chemistry or roughness, but rather to a combination of the hydrophilic nature and the defect state of the surface.
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Simon, Hélène A. "Influence of the implant location on the hinge and leakage flow fields through bileaflet mechanical heart valves." Available online, Georgia Institute of Technology, 2004:, 2003. http://etd.gatech.edu/theses/available/etd-04012004-192539/unrestricted/helene%5Fsimon%5Fa%5F200405%5Fmast.pdf.

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Thesis (M.S.)--Chemical Engineering, Georgia Institute of Technology, 2003.
Sambanis Athanassios, Committee Member ; Sotiropoulos Fotis, Committee Member ; Yoganathan Ajit, Committee Chair. Includes bibliographical references (leaves 239-243).
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Kidani, Derrick D. A. "Surface modifications to improve the biocompatibility of polymeric vascular prostheses." Thesis, Georgia Institute of Technology, 1997. http://hdl.handle.net/1853/11263.

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Yap, Cheng-Hon. "Factors influencing cryopreserved allograft heart valve degeneration." Connect to thesis, 2006. http://repository.unimelb.edu.au/10187/2120.

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Heart valve replacement is becoming more commonplace in developed nations. Despite this the ideal valve prosthesis has not been found. The allograft valve has been used for over 40 years and remains an important prosthesis with many advantages. However, like other biological valve prosthesis, they have a finite durability. The causes of allograft valve degeneration are still unknown. The study aims to identify factors associated with cryopreserved allograft valve degeneration. Knowledge of such factors will improve our understanding of the potential causes and mechanisms of allograft heart valve degeneration. (For complete abstract open document)
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Murphy, David Wayne. "The application of passive flow control to bileaflet mechanical heart valve leakage jets." Thesis, Atlanta, Ga. : Georgia Institute of Technology, 2009. http://hdl.handle.net/1853/31700.

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Thesis (M. S.)--Mechanical Engineering, Georgia Institute of Technology, 2010.
Committee Co-Chair: Ajit Yoganathan; Committee Co-Chair: Ari Glezer; Committee Member: Rudy Gleason. Part of the SMARTech Electronic Thesis and Dissertation Collection.
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Bachlah, Dana Mohamad. "Modeling of the inner structural band of the aortic valve bio prosthesis." Bachelor's thesis, Igor Sikorsky Kyiv Polytechnic Institute, 2021. https://ela.kpi.ua/handle/123456789/43660.

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Обсяг дипломної роботи становить 73 сторінок, містить 28 ілюстрацій, 20 таблиць. Загалом опрацьовано 59 джерел. Актуальність: Захворювання аортального клапана призводять до серйозних дисфункцій, спричинених зворотним потоком клапана або підвищенням його опору. Наслідком цієї патології є важка серцева недостатність, скорочення тривалості та якість життя. Єдине лікування - хірургічна заміна клапана на штучний протез або пластику аортального клапана. Заміна хворого аортального клапана на штучний протез є ефективним методом профілактики серцевої недостатності, збільшення тривалості та поліпшення якості життя. Мета: Моделювання внутрішньої структурної смуги біопротезу аортального клапана. Завдання: переглянути літературу з анатомії судин та клапанів серця; проаналізувати та виявити проблему; побудувати внутрішню структурну клапанну модель клапана у винахіднику AutoCAD; Аналіз варіантів матеріалів для виготовлення клапанного корпусу показав прийнятні механічні характеристики та біосумісність. Основні результати: переглянуто літературу з суміжних тем; порівняльний аналіз існуючих прототипів штучних клапанів серця; вибір «біологічного нітинолу»; Розроблено 5 стандартних розмірів каркаса для біопротезування аортального клапана.
The volume of the graduation work is 73 pages, contains 28 illustrations, 20 tables. In total 59 sources have been processed. Relevance: Aortic valve diseases lead to its severe dysfunction caused backflow on the valve or increased its resistance. The consequence of this pathology is severe heart failure, reduced duration and quality of life. The only treatment is surgical replacement of the valve with an artificial prosthesis or aortic valve plastic. Replacing of a sick aortic valve with an artificial prosthesis is an effective method of preventing heart failure, increasing duration and improving quality of life. Purpose: Modeling of the inner structural band of the aortic valve bio prosthesis. Tasks: to review literature on anatomy of blood vessels and heart valves; analyze and identify the problem; build inner structural band valve model in AutoCAD inventor; analyze the material options for the manufacture of the valve frame showed acceptable mechanical characteristics and biocompatibility. Main results: literature on related topics has been reviewed; comparative analysis of existing prototypes of artificial heart valves; selection of “biological nitinol”; 5 standard sizes of frame for aortic valve bio prosthesis was designed.
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Meneses, LÃdia Stella Teixeira de. "Self-care practice of evaluation of patients with mechanical heart valve prosthesis." Universidade Federal do CearÃ, 2014. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=15151.

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nÃo hÃ
Os pacientes com prÃtese cardÃaca valvar mecÃnica exigem acompanhamento regular da equipe de saÃde durante a vida, com vistas a praticar o autocuidado para recuperaÃÃo e promoÃÃo da sua saÃde. Tem-se como objetivo avaliar a prÃtica do autocuidado de pacientes com prÃtese valvar mecÃnica, acompanhados na consulta de enfermagem. Como objetivos especÃficos tÃm-se: identificar os fatores condicionantes para a prÃtica do autocuidado, considerando indicadores sociodemogrÃficos e clÃnicos; verificar as prÃticas de autocuidado e os dÃficits de autocuidado de pacientes portadores de prÃtese valvar mecÃnica; e levantar os consequentes decorrentes do dÃficit de autocuidado. Estudo descritivo e transversal, desenvolvido em dois ambulatÃrios de valvopatias de hospitais escola de Fortaleza-Ce. CompÃs a amostra 127 pacientes com prÃtese valvar mecÃnica. Coletou-se os dados por meio de entrevista, avaliaÃÃo da pressÃo arterial e medidas antropomÃtricas. O projeto foi aprovado pelo Comità de Ãtica e Pesquisa (No 422.098). Como resultados dos fatores condicionantes predominaram: sexo feminino (56,7%), faixa etÃria 40 a 59 anos (50,4%), estudaram mais de 5 anos (69,2%), casados/uniÃo estÃvel (63,8%), procedentes de Fortaleza (54,3%), renda familiar de atà um salÃrio mÃnimo (53,5%), cor da pele nÃo-branca (55,1%) e nÃo exerce atividade laboral (80,3%). As prÃticas de autocuidado universal de maior incidÃncia foram: higiene corporal (cabelos lavados-97,6%, banho diÃrio-92,1%); higiene oral (escova os dentes ao dormir-87,4%); ingestÃo de lÃquidos (ingere Ãgua potÃvel-95,2%); ingestÃo de alimentos (ingestÃo de sal < 2g/dia-92,1%, consumo de vegetais e frutas diariamente- 79,5%); eliminaÃÃes intestinais (sem sangue, muco ou secreÃÃo purulenta-96%, ausÃncia de parasitas-94,4%); eliminaÃÃes urinÃrias (ausÃncia de sangue ou pus-96,8%, frequÃncia urinÃria de 4 a 6 vezes ao dia-96%). Como requisitos de autocuidado desenvolvimental predominaram: nunca usou drogas ilÃcitas, nem fumou, nem bebeu ou parou na descoberta da doenÃa (70%). Como requisitos de autocuidado desvio de saÃde tem-se: faz uso de medicaÃÃo certa na dose certa (95,2%); comparecimento Ãs consultas da equipe de saÃde (cardiologista-92,1%; enfermagem-84,2%); controle do INR (identifica sinais de sangramento-85,8%); e conhecimento (57,4%). Os dÃficits de autocuidado universal foram: higiene corporal (unhas grandes ou sujas-43,6%, faz depilaÃÃo com aparelho manual-77,2%), higiene oral (nÃo usa fio dental-70,9%, usa palito de dentes-71,7%, nÃo realiza visita ao dentista-65,4%), ingestÃo de alimentos (consumo desregular de alimentos que contem vitamina k - 33,1%, faz poucas refeiÃÃes por dia- 36,3%); prÃtica de exercÃcio fÃsico (nÃo usa roupas adequadas-62,3%, faz exercÃcio fÃsico menos de 30 min-65,4%, faz exercÃcio fÃsico menos de 5 vezes na semana-70,9%,); sono e repouso (demora a dormir-37,1%). Como dÃficit de autocuidado de desvio de saÃde destacou-se: nÃo realiza controle laboratorial do INR (55,2%). Os consequentes do dÃficit de AC predominaram: eventos hemorrÃgicos (55,1%) e tromboembÃlicos (13,4%). Conclui-se que nenhum paciente com valva cardÃaca mecÃnica segue todas as prÃticas de autocuidado nos requisitos universais, desenvolvimentais e desvio de saÃde recomendadas, assim como nenhuma prÃtica à seguida por todos os participantes do estudo. Portanto, à necessÃrio que os profissionais dos ambulatÃrios de valvopatias estabeleÃam estratÃgias para reduÃÃo do dÃficit de autocuidado, considerando os fatores condicionantes do autocuidado dos pacientes.
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Books on the topic "Heart valve prosthesis"

1

Love, Jack. Autologous tissue heart valves. Austin: R.G. Landes Co., 1993.

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2

Symposium on Current Concepts on the Use of Aortic and Pulmonary Allografts for Heart Valve Substitutes (1987 Berlin, Germany). Cardiac valve allografts, 1962-1987: Current concepts on the use of aortic and pulmonary allografts for heart valve substitutes : proceedings of the Symposium on Current Concepts on the Use of Aortic and Pulmonary Allografts for Heart Valve Substitutes, Berlin (West), September 7-9, 1987. Darmstadt: Steinkopff, 1988.

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3

Zabalgoitia, Miguel. Echocardiography of prosthetic heart valves. Austin: R.G. Landes Co., 1994.

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4

Carlos, Gomez-Duran, Reul George J, and St Jude Medical Inc, eds. Indications for heart valve replacement by age group. Boston: Kluwer Academic Publishers, 1989.

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5

Institution of Mechanical Engineers (Great Britain) and Institution of Mechanical Engineers (Great Britain). Engineering in Medicine Section., eds. Heart valve engineering: Papers presented at a seminar organized by the Engineering in Medicine Group of the Institution of Mechanical Engineers and held at the Institution of Mechanical Engineers on 4-5 December 1986. London: Published by Mechanical Engineering Publications for the Institution of Mechanical Engineers, 1986.

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6

European Symposium on the St. Jude Medical Valve (2nd 1984 Düsseldorf, Germany). Update in heart valve replacement: Proceedings of the Second European Symposium on the St. Jude Medical Heart Valve. Darmstadt: Steinkopff, 1986.

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7

Gregorio, Rábago, and Cooley Denton A. 1920-, eds. Heart valve replacement & future trends in cardiac surgery. Mount Kisco, N.Y: Futura Pub. Co., 1987.

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8

Endre, Bodnar, Yacoub Magdi, Cardiothoracic Institute (London England), National Heart Hospital (London, England), and International Symposium on Cardiac Bioprostheses. (3rd : 1985 : London, England), eds. Biologic & bioprosthetic valves: Proceedings of the third international symposium. [New York?]: Yorke Medical Books, 1986.

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Endre, Bodnar, and Frater Robert, eds. Replacement cardiacvalves. New York: Pergamon, 1991.

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Zussa, Claudio. Artificial chordae in mitral valve surgery. Austin: R.G. Landes Co., 1994.

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Book chapters on the topic "Heart valve prosthesis"

1

Aberle, Corinne M., Chrisita L. Powlett, and Jennifer R. Cozart. "Valve Prosthesis." In Valvular Heart Disease, 223–35. London: Springer London, 2019. http://dx.doi.org/10.1007/978-1-4471-2840-3_11.

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Emani, Sitaram M. "Mitral Valve Replacement with Melody Valve Prosthesis." In Fetal and Hybrid Procedures in Congenital Heart Diseases, 367–75. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-40088-4_44.

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Deville, C., F. Madonna, S. A. M. Nashef, and C. Doutremepuich. "Anticoagulant therapy and heart valve prosthesis." In Anticoagulation, 376–80. New York, NY: Springer New York, 1994. http://dx.doi.org/10.1007/978-1-4612-2668-0_20.

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Rose, Alan G. "Design, Classification and Identification of Prosthetic Heart Valves: Gross Examination of the Heart containing a Prosthesis, Analysis of Removed Prostheses." In Pathology of Heart Valve Replacement, 24–44. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-3227-2_3.

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Fraile, J., J. Martinell, V. Artiz, C. F. Kizner, J. M. Arribas, B. Viñals, J. Moya, and J. G. Puente. "ATS Medical mechanical valve prosthesis in reoperations." In Advancing the Technology of Bileaflet Mechanical Heart Valves, 101–10. Heidelberg: Steinkopff, 1998. http://dx.doi.org/10.1007/978-3-642-93691-3_11.

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Dalichau, H., H. Nigbur, J. Kalotai, and A. Schmitz-Köhler. "Experience with the St. Jude medical heart valve prosthesis." In Invasive Cardiovascular Therapy, 106–20. Dordrecht: Springer Netherlands, 1987. http://dx.doi.org/10.1007/978-94-009-4293-6_10.

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Chatterjee, S., and T. J. Gardner. "Factors Determining Selection of Valve Prosthesis - Tissue or Mechanical: Current Status." In Pathophysiology, Evaluation and Management of Valvular Heart Diseases, 189–94. Basel: KARGER, 2002. http://dx.doi.org/10.1159/000058927.

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Deverall, P. B. "Thromboembolic Complications in Pediatric Patients Undergoing Valve Replacement with the St. Jude Medical® Prosthesis." In Indications for Heart Valve Replacement by Age Group, 25–28. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-6900-4_4.

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Burckhardt, D., D. Striebel, S. Vogt, A. Hoffmann, J. Roth, U. Althaus, J. J. Goy, H. Sadeghi, and E. Grädel. "Heart Valve Replacement with the St. Jude Medical® Valve Prosthesis: Long-Term Experience in 743 Patients Receiving Valve Implants in Switzerland." In Indications for Heart Valve Replacement by Age Group, 323–24. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-6900-4_35.

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10

Arom, K. V., D. M. Nicoloff, W. G. Lindsay, W. F. Northrup, T. E. Kersten, and R. W. Emery. "Aortic and Mitral Valve Replacement with the St. Jude Medical® Prosthesis: A Nine-Year Update Report." In Indications for Heart Valve Replacement by Age Group, 301–9. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-6900-4_33.

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Conference papers on the topic "Heart valve prosthesis"

1

Corbett, Scott C., Neil Verma, Parnian Boloori Zadeh, Ahmet U. Coskun, and Hamid N.-Hashemi. "Characterization of a Novel Polymeric Trileaflet Heart Valve Prosthesis." In ASME 2009 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2009. http://dx.doi.org/10.1115/sbc2009-203817.

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While heart valve prostheses have been used successfully since 1960, 10-year survival rates still range from 37–58% [1]. The underlying problem with bioprostheses is a limited life from structural changes such as calcification and leaflet wear, leading to valve failure [2]. Biological tissue fixation and methods used to mount the tissue to a supporting stent can be blamed for this shortcoming. The underlying problem with mechanical heart valves is the presence of a centrally located leaflet, or occluder. It propagates high velocity jets, turbulence and areas of stagnation: the disturbances which necessitate anticoagulation [3]. A polyurethane valve has the potential to improve upon the shortcomings of existing valves and ultimately improve patient survival.
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2

Kwon, Young Joo. "A Comparative Study of Structural Analyses for Flat and Curved Mechanical Heart Valve Prostheses to Enhance Durability." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-41184.

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This paper addresses a comparative study of structural analyses for flat and curved mechanical heart valve prostheses. The same fluid force computed by the fluid mechanics analysis for the blood flow passing through the leaflets of a bileaflet mechanical heart valve prosthesis is used to both flat and curved mechanical heart valve prostheses for comparison. This fluid force is applied to both mechanical heart valve prostheses for the rigid body dynamics analyses to confirm the kinematic and dynamic characteristics of leaflet motions, the structural mechanics analyses for deformed leaflets of both flat and curved mechanical heart valve prostheses are executed to give quite different stress and deflection results even though they have the almost same kinematic and dynamic characteristics.
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3

Kim, Jung Kyung, Jaeyong Sung, Jung Yul Yoo, Jun Keun Chang, and Byoung Goo Min. "PIV Measurements of Flow Distal to Polyurethane Heart Valve Prosthesis Under Steady and Pulsatile Flow Conditions." In ASME 1999 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1999. http://dx.doi.org/10.1115/imece1999-0376.

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Abstract Hemodynamic performance of a polyurethane heart valve prosthesis was evaluated in comparison with that of Björk-Shiley Monostrut mechanical valve in steady and pulsatile flow. Pressure losses through the valves were obtained from the streamwise pressure distributions downstream of the valves under steady flow condition. Unsteady and turbulent flow through the heart valve prostheses were investigated using PIV in conjunction with the opening behaviors of valve leaflets. Direct measurements of the wall shear stress by hot-film anemometry (HFA) were compared with the PIV data. By examining the velocity field downstream of the polyurethane heart valve, it is known that high shear stress regions exist at the interface between strong axial jet flows along the wall and vortical flows in the central area. In addition, there are large recirculation regions near the valve, where thrombus formation can be induced by accumulation of damaged blood cells. A correlation between the flow pattern downstream of the valve and the corresponding opening posture of the polyurethane valve leaflet gives useful data necessary for improved design of the superstructure and leaflet geometry of the valve.
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4

Holzamer, A., M. Zerdzitzki, K. Debl, M. Creutzenberg, M. Fischer, C. Schmid, and M. Hilker. "Early Experience with a Novel Transcatheter Tricuspid Heart Valve Prosthesis." In 48th Annual Meeting German Society for Thoracic, Cardiac, and Vascular Surgery. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1678845.

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5

Griffith, Boyce E., Vittoria Flamini, Abe DeAnda, and Lawrence Scotten. "Simulating the Dynamics of an Aortic Valve Prosthesis in a Pulse Duplicator: Numerical Methods and Initial Experience." In ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/fmd2013-16185.

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Each year, approximately 50,000 aortic valve replacement operations are performed in the United States, but despite decades of development, many of the limitations of aortic valve prostheses remain consequences of the fluid dynamics induced by the replacement valve. We aim to develop detailed fluid-structure interaction (FSI) models of aortic valve prostheses mounted within a ViVitro Systems, Inc. pulse duplicator. Here, we describe numerical methods for simulating FSI with rigid structures, such as the leaflets of a mechanical heart valve, and we present initial three-dimensional simulation studies of the fluid dynamics of a St. Jude Regent bileaflet valve prosthesis.
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6

Adlparvar, Payam, George Guo, and Chris Kingsbury. "Motion analysis of mechanical heart valve prosthesis utilizing high-speed video." In 20th International Congress on High Speed Photography and Photonics, edited by John M. Dewey and Roberto G. Racca. SPIE, 1993. http://dx.doi.org/10.1117/12.145799.

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7

Castellini, P., M. Pinotti, and L. Scalise. "Particle image velocimetry for flow analysis in mechanical artificial heart valves." In European Conference on Biomedical Optics. Washington, D.C.: Optica Publishing Group, 2001. http://dx.doi.org/10.1364/ecbo.2001.4434_187.

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Red blood cell damage (hemolysis) and thromboemblism are the main complications associated to the implantation of mechanical artificial heart valves. In the last decades a great number of in vitro studies have been conducted to improve the design and to understand the transvalvular flow patterns under steady state and pulsatile conditions. Steady state tests are useful to study the flow established upstream and downstream the valve prosthesis in the moment of the peak flow rate. In the present study, Particle Image Velocimetry (PIV) technique was employed to visualise the flow patterns in a precommercial model of bi-leaflet mechanical heart valve prosthesis in a steady state flow. PIV technique and a convenient test rig have provided good conditions to investigate the whole flowfield upstream and downstream the valve.
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8

Pengo, V., M. Boschello, P. Peruzzi, D. Pagotto, L. Schivazappa, and S. Dalla Volta. "PATIENTS WITH ARTIFICIAL BUT NOT BIOLOGICAL HEART VALVE PROSTHESIS PRESENT A HYPERCOAGULABILITY RELATED TO THE INTENSITY OF ANTICOAGULATION." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643878.

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Long term anticoagulant therapy is mandatory for patients with artificial heart valve prosthesis and is suggested for some patients with biological heart valve prosthesis. Oral anticoagulants reduce but not abolish thromboembolic complication in these patients. They act lowering the level of vitamin K-dependent coagulation factors and that in turn should result in a depression of "in vivo" thrombin formation. Fibrinopeptide A (FpA) is a good marker of thrombin formation and therefore we ascertained in several occasions the thrombin formation in 43 patients with artificial and 18 with biological heart valve prosthesis, all the patients being on oral anticoagulant treatment at least from 1 year. FpA was significantly higher in patients with artificial (determinations n = 138) with respect to biological (n=73) heart valve prosthesis (p 0.01). The FpA level in biological valves was close to that obtained in 22 not anticoagulated healthy subjects. When we divided FpA values in artificial heart valves according to the intensity of anticoagulation, we obtained a decreasing FpA mean levels with the increase of the degree of anticoagulation. In particular FpA values with an INR 4.5 were close to values obtained in healthy subjects. These data support the concept that patients with artificial heart valves are at higher risk of thromboembolism and therefore the intensity of anticoagulation should be different with respect to biological valves and probably a little higher than that recommended at the Leuven Consensus Conference.
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9

Wang, Jong H., George Guo, Stefan Schreck, and Michael Prisco. "A Numerical Study of Flow Through a Mechanical Heart Valve." In ASME 1996 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1996. http://dx.doi.org/10.1115/imece1996-1221.

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Abstract The purpose of this study was to develop a numerical model for simulating the flow through a Mechanical Heart Valve (MHV), for which a good understanding of the detailed flow information is desired. This is because that fluid mechanics may play an important role in the thrombus formation and hemolysis in the mechanical valve prosthesis.
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10

Kouhi, Esfandyar, and Yos Morsi. "Fluid Structure Interaction Analysis of Stentless Bio-Prosthetic Aortic Heart Valve in Sinus of Valsalva." In ASME 2010 International Mechanical Engineering Congress and Exposition. ASMEDC, 2010. http://dx.doi.org/10.1115/imece2010-39386.

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In this paper the fluid structure interaction in stentless aortic heart valve during acceleration phase was performed successfully using the commercial ANSYS/CFX package. The aim is to provide unidirectional coupling FSI analysis of physiological blood flow within an anatomically corrected numerical model of stentless aortic valve. Pulsatile, Newtonian, and turbulent blood flow rheology at aortic level was applied to fluid domain. The proposed structural prosthesis had a novel multi thickness leaflet design decreased from aortic root down to free age surface. An appropriate interpolation scheme used to import the fluid pressure on the structure at their interface. The prosthesis deformations over the acceleration time showed bending dominant characteristic at early stages of the cardiac cycle. More stretching and flattening observed in the rest of the times steps. The multi axial Von Mises stress data analysis was validated with experimental data which confirmed the initial design of the prosthesis.
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