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Books on the topic 'Heart transplantate'

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Author: Grafiati

Published: 11 March 2023

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1

L, Rose Marlene, and Yacoub Magdi, eds. Immunology of heart and lung transplantation. London: Edward Arnold, 1993.

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2

J, Shumway Sara, and Shumway N. E. 1923-, eds. Thoracic transplantation. Cambridge, Mass., USA: Blackwell Science, 1995.

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3

L, Franco Kenneth, ed. Pediatric cardiopulmonary transplantation. Armonk, N.Y: Futura Pub., 1997.

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4

Javier, Guerrero Gimeno, ed. Deuda de sangre. Barcelona: RBA Libros, 2014.

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5

Heat shock response and organ preservation: Models of stress conditioning. New York: Springer, 1997.

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6

Fox, Renée C. Spare parts: Organ replacement in American Society. New York: Oxford University Press, 1992.

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7

Roger, Herdman, and Institute of Medicine (U.S.). Division of Health Care Services., eds. Non-heart-beating organ transplantation: Medical and ethical issues in procurement. Washington, D.C: National Academy Press, 1997.

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8

Smith, Martin. Beating heart organ donation. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0389.

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Transplantation is the optimal treatment of end-stage dysfunction of many organs and can be life-saving. Despite increases in live donation and donation after circulatory death, donation after brain death remains the most important source of donor organs, and is currently the only source of thoracic organs in most countries. Brain death is associated with profound physiological changes including cardiovascular and respiratory changes, and severe metabolic and endocrine dysfunction that can jeopardize transplantable organ function. Although adequate time must be allowed for the proper confirmation of brain death, unnecessary delays should be avoided because the incidence of systemic complications that jeopardize transplantable organ function increases progressively with time. Aggressive donor management increases the number of potential donors who actually become donors, increases the total number of organs transplanted per donor, and improves transplantation outcomes. Various donor management strategies have been described and these are reviewed in this chapter.

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9

Rady, Mohamed Y., and Ari R. Joffe. Non-heart-beating organ donation. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199600830.003.0390.

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The transplantation community endorses controlled and uncontrolled non-heart-beating organ donation (NHBD) to increase the supply of transplantable organs at end of life. Cardiac arrest must occur within 1–2 hours after the withdrawal of life-support in controlled NHBD. Uncontrolled NHBD is performed after failed cardiopulmonary resuscitation in an unexpected witnessed cardiac arrest. Donor management aims to protect transplantable organs against warm ischaemic injury through the optimization of haemodynamics and mechanical ventilation. This also requires antemortem instrumentation and systemic anticoagulation for organ perseveration in controlled NHBD. Interval support with extracorporeal membrane oxygenation or cardiopulmonary bypass is generally required for optimal organ perfusion and oxygenation in uncontrolled NHBD, which remains a controversial medical practice. There are several unresolved ethical challenges. The circulatory criterion of 2–10 minutes of absent arterial pulse does not comply with the uniform determination of death criterion of the irreversible cessation of functions of the cardiovascular or central nervous systems. There are no robust safeguards in clinical practice that can prevent faulty prognostication, and premature withdrawal of treatment or termination of cardiopulmonary resuscitation. Unmanaged conflicting interests of increasing the supply of transplantable organs can have serious consequences on the medical care of potentially salvageable patients. Perimortem interventions can interfere with the delivery of an optimal quality of end-of-life care. The lack of disclosure of these NHBD ethical controversies does not uphold the moral obligation for an informed consent.

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10

Knife to the Heart. Macmillan, 1996.

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11

Stark, Tony. Knife to the Heart. Pan Macmillan, 1997.

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12

Knife to the Heart: Story of Transplant Surgery. Macmillan, 1997.

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13

Novel Approaches to Transplantation. Royal Society of Medicine Press Ltd, 1997.

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14

(Editor), Marlene L. Rose, and Magdi H. Yacoub (Editor), eds. Immunology of Heart and Lung Transplantation (Hodder Arnold Publication). A Hodder Arnold Publication, 1993.

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15

M, Körner M., Posival H, and Körfer Reiner, eds. Thoracic organ transplantation: Routine as a challenge : proceedings of the third international symposium held in Bad Oeynhausen, 9-11 September 1993. Amsterdam: Excerpta Medica, 1994.

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