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1

Ithuralde, Mariano, and Rodolfo Neirotti. "Neonatal Heart Surgery: Evaluation of Risk Factors." NeoReviews 12, no. 5 (May 2011): e252-e259. http://dx.doi.org/10.1542/neo.12-5-e252.

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2

Shinkai, Noriko, Takeshi Morimoto, Hisako Yano, and Tadaaki Koyama. "Risk Factors for SSI after Open Heart Surgery." Japanese Journal of Cardiovascular Surgery 48, no. 3 (May 15, 2019): 161–69. http://dx.doi.org/10.4326/jjcvs.48.161.

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3

Krasheninnikov, S., A. Levit, I. Belyaev, S. Bozhesku, and R. Serov. "Risk factors for respiratory failure after heart surgery." Journal of Cardiothoracic and Vascular Anesthesia 34 (October 2020): S53. http://dx.doi.org/10.1053/j.jvca.2020.09.075.

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4

Ivanova, L. N., V. I. Boltenkova, E. V. Ivanova, and E. P. Evseev. "Risk factors of postpericardiotomy syndrome after heart valve surgery." Kardiologiya i serdechno-sosudistaya khirurgiya 14, no. 4 (2021): 308. http://dx.doi.org/10.17116/kardio202114041308.

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5

Jones, J. Mark, Hugh O'Kane, Dennis J. Gladstone, Mazin A. I. Sarsam, Gianfranco Campalani, Simon W. MacGowan, Jack Cleland, and Gordon W. Cran. "Repeat heart valve surgery: Risk factors for operative mortality." Journal of Thoracic and Cardiovascular Surgery 122, no. 5 (November 2001): 913–18. http://dx.doi.org/10.1067/mtc.2001.116470.

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6

Chiolero, R., A. Borgeat, and A. Fisher. "Postoperative Arrhythmias and Risk Factors after Open Heart Surgery." Thoracic and Cardiovascular Surgeon 39, no. 02 (April 1991): 81–84. http://dx.doi.org/10.1055/s-2007-1013937.

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7

Yamamura, Mitsuhiro, Masataka Mitsuno, Hiroe Tanaka, Yasuhiko Kobayashi, Masaaki Ryomoto, Hiroyuki Nishi, Shinya Fukui, Noriko Tsujiya, Tetsuya Kajiyama, and Yuji Miyamoto. "Risk factors for open heart surgery in hemodialysis patients." General Thoracic and Cardiovascular Surgery 57, no. 5 (May 2009): 235–38. http://dx.doi.org/10.1007/s11748-008-0372-2.

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8

Tibekina, L. M., E. G. Smertina, V. D. Zolotov, A. O. Zaitseva, A. P. Kretsu, M. S. Stolyarov, M. S. Kamenskikh, M. V. Starosotskaya, and D. V. Shmatov. "Risk factors of cerebral complications after cardiac surgery." Grekov's Bulletin of Surgery 176, no. 3 (June 28, 2017): 61–66. http://dx.doi.org/10.24884/0042-4625-2017-176-3-61-66.

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OBJECTIVE. The authors defined the risk factors of cerebral complications after cadiosurgical operations. MATERIAL AND METHODS. The patients with ischemic heart disease who underwent coronary artery bypass grafting (CABG) were included in the first group (n=189) 132 (69,8 %) men and 57 (30,2 %) women aged 62,5 ± 8,3 years old. The patients who underwent reconstructive surgery of the heart valves were in the second group (n=50) and numbered 34 (68 %) men and 16 (32 %) women aged 63,1 ± 7,7 years old. The operations on valves were performed under conditions of extracorporeal circulation in the Center of Cardiosurgery and Interventional Cardiology of St. Petersburg Multidisciplinary Center. RESULTS. The research showed that the proportion of severe cerebral complications such as acute stroke and delirium was equal to 7,4 % in patients with coronary artery bypass grafting, while in group of patients with valvular pathology it numbered 14,0 %. The proportion of patients with delirium was 5,8 % in the first group and it consisted of 12 % in the second group. The number of patients with stroke was 1,58 % in the first group and it counted 2,0 % in the second group. Chronic cerebrovascular failure, stroke in the anamnesis, fibrillations of auricles and post-infarction cardiosclerosis were the leading risk factors of acute stroke development in early postoperative period. CONCLUSIONS. There was noted that such risk factors as postinfarction cardiosclerosis, stroke in the anamnesis and also the constrictive atherosclerosis of brachiocephalic trunk were associated with the group of patients who had cerebral complications after CABG operation. The proportion of patients with fibrillations of auricles (paroxysmal form) and a low left ventricular ejection fraction was higher in group of patients who underwent reconstructive surgery of the heart valves. The frequency of tobacco smoking was high among patients in both subgroups (77 % and 57,1 %).
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9

Basile, A., S. Bernazzali, F. Diciolla, F. Lenzini, G. Lisi, M. Maccherini, V. Mangini, E. Nesti, and M. Chiavarelli. "Risk factors for smoking abuse after heart transplantation." Transplantation Proceedings 36, no. 3 (April 2004): 641–42. http://dx.doi.org/10.1016/j.transproceed.2004.02.054.

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10

Almenar, L., M. L. Cardo, L. Martı́nez-Dolz, C. Garcı́a-Palomar, J. Rueda, E. Zorio, M. Á. Arnau, A. Osa, and M. Palencia. "Risk Factors Affecting Survival in Heart Transplant Patients." Transplantation Proceedings 37, no. 9 (November 2005): 4011–13. http://dx.doi.org/10.1016/j.transproceed.2005.09.160.

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11

Kim, Tae Kwan, Jun Rho Yoon, Yu Na Choi, Ui Jin Park, Kyoung Rim Kim, and Taehee Kim. "Risk factors of emergency reoperations." Anesthesia and Pain Medicine 15, no. 2 (April 30, 2020): 233–40. http://dx.doi.org/10.17085/apm.2020.15.2.233.

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Background: Emergency reoperation is considered to be a quality indicator in surgery. We analyzed the risk factors for emergency reoperations. Methods: Patients who underwent emergency operations from January 1, 2017, to December 31, 2017, at our hospital were reviewed in this retrospective study. Multivariate logistic regression was performed for the perioperative risk factors for emergency reoperation.Results: A total of 1,481 patients underwent emergency operations during the study period. Among them, 79 patients received emergency reoperations. The variables related to emergency reoperation included surgeries involving intracranial and intraoral lesions, highest mean arterial pressure ≥ 110 mmHg, highest heart rate ≥ 100 /min, anemia, duration of operation >120 min, and arrival from the intensive care unit (ICU). Conclusions: The type of surgery, hemodynamics, hemoglobin values, the duration of surgery, and arrival from ICU were associated with emergency reoperations.
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12

Mrowczynski, Wojciech, Michal Wojtalik, Danuta Zawadzka, Girish Sharma, Jacek Henschke, Rafal Bartkowski, Malgorzata Pawelec-Wojtalik, Andrzej Wodzinski, and Przemyslaw Westerski. "Infection Risk Factors in Pediatric Cardiac Surgery." Asian Cardiovascular and Thoracic Annals 10, no. 4 (December 2002): 329–33. http://dx.doi.org/10.1177/021849230201000411.

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Cardiac operations were preformed in 499 children from January 1998 through December 1999. Their median age was 263 days. A positive culture from blood, bronchoalveolar lavage, wound, or central catheter was obtained in 110 patients (22%). Age, sex, presence of pulmonary hypertension, body surface area, ratio of body surface area to oxygenator surface area, whether heart surgery was open or closed, and the duration of the operation, cardiopulmonary bypass, intubation, and intensive care were analyzed. Patients who developed infections were significantly younger, with smaller body surface areas and disparity with the oxygenator surface area, longer operative and bypass times, extended intubation, and prolonged intensive care. There was a significant correlation between infection and pulmonary hypertension. Sex and type of operation were not predictors of infection.
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13

Batiha, Abdul-Monim Mohammad, Ibtisam Al-Zaru, Majdee Saiah AL-Shaarani, and Fadwa N. Alhalaiqa. "Pulmonary complications after open heart surgery: A retrospective study." International Journal of Emerging Trends in Health Sciences 5, no. 1 (April 30, 2021): 01–12. http://dx.doi.org/10.18844/ijeths.v5i1.5300.

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Despite significant advances in open heart surgery over the last two decades, postoperative pulmonary complications (PPCs) are considered the most important causes that contribute to patient morbidity, mortality and prolonged hospital stay. The ultimate goal of this paper was to investigate the risk factors which increasing the incidence rate of pulmonary complications after open heart surgery of Jordanian patients. A retrospective design using an existing coronary artery surgery database of adults (n = 200) who had undergone open heart surgery between August 2014 and July 2015 at a University Hospital in Jordan. A structured PPCs instrument was used to assess ‘PPCs risk factors assessment sheet’. According to the results, the proposed model provides a preliminary indication of risk factors placing open heart surgical patients at risk of PPCs. Determining patients who are at risk of developing PPC’s after cardiac surgeries are the first step towards its prevention. This reduces its burden in term of morbidity, mortality and cost. Keywords: Jordan, open heart surgery, predictors, pulmonary complications, risk factors.
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14

Kim, Yuli Y., Wei He, Thomas E. MacGillivray, and Oscar J. Benavidez. "Readmissions after adult congenital heart surgery: Frequency and risk factors." Congenital Heart Disease 12, no. 2 (December 19, 2016): 159–65. http://dx.doi.org/10.1111/chd.12433.

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15

Arif, Rawa, Philipp Seppelt, Simon Schwill, Dubravka Kojic, Ali Ghodsizad, Arjang Ruhparwar, Matthias Karck, and Klaus Kallenbach. "Predictive Risk Factors for Patients With Cirrhosis Undergoing Heart Surgery." Annals of Thoracic Surgery 94, no. 6 (December 2012): 1947–52. http://dx.doi.org/10.1016/j.athoracsur.2012.06.057.

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16

Perez, Alexander, Hiromichi Ito, Robert S. Farivar, Lawrence H. Cohn, John G. Byrne, James D. Rawn, Sary F. Aranki, et al. "Risk factors and outcomes of pancreatitis after open heart surgery." American Journal of Surgery 190, no. 3 (September 2005): 401–5. http://dx.doi.org/10.1016/j.amjsurg.2005.03.004.

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17

Raatz, Anna, Martin Schöber, Robert Zant, Robert Cesnjevar, André Rüffer, Ariawan Purbojo, Sven Dittrich, and Muhannad Alkassar. "Risk factors for chylothorax and persistent serous effusions after congenital heart surgery." European Journal of Cardio-Thoracic Surgery 56, no. 6 (July 10, 2019): 1162–69. http://dx.doi.org/10.1093/ejcts/ezz203.

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Abstract OBJECTIVES This study evaluated the various risk factors for chylothorax and persistent serous effusions (>7 days) after congenital heart surgery and developed equations to calculate the probability of their occurrence. METHODS We performed a retrospective review of different medical databases at the University Hospital of Erlangen between January 2014 and December 2016. Full model regression analysis was used to identify risk factors, and prediction algorithms were set up to calculate probabilities. Discriminative power of the models was checked with the help of C-statistics. RESULTS Of 745 operations on 667 patients, 68 chylothoraxes (9.1%) and 125 persistent pleural effusions (16.8%) were diagnosed. Lowest temperature [P = 0.043; odds ratio (OR) 0.899], trisomy 21 (P = 0.001; OR 5.548), a higher vasoactive inotropic score on the day of surgery (P = 0.001; OR 1.070) and use of an assist device (P = 0.001; OR 5.779) were significantly associated with chylothorax. Risk factors for persistent serous effusions were a given or possible involvement of the aortic arch during the operation (P = 0.000; OR 3.982 and 2.905), univentricular hearts (P = 0.019; OR 2.644), a higher number of previous heart operations (P = 0.014; OR 1.436), a higher vasoactive inotropic score 72 h after surgery (P = 0.019; OR 1.091), a higher central venous pressure directly after surgery (P = 0.046; OR 1.076) and an aortic cross-clamp time >86 min (P = 0.023; OR 2.223), as well as use of an assist device (P = 0.002; OR 10.281). The prediction models for both types of effusions proved to have excellent discriminative power. CONCLUSIONS Persistent serous effusion is associated with a higher vasoactive inotropic score 72 h after surgery, an aortic cross-clamp time >86 min and elevated central venous pressure directly after surgery, which, in combination, potentially indicate cardiac stress. The developed logistic algorithm helps to estimate future likelihood.
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18

Ricco, Jean Baptiste. "Intermittent claudication, heart disease risk factors, and mortality." Journal of Vascular Surgery 15, no. 4 (April 1992): 737–38. http://dx.doi.org/10.1016/0741-5214(92)90036-8.

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19

Bahar, Ilknur, Ahmet Akgul, Mehmet Ali Ozatik, Kerem M. Vural, Ali E. Demirbag, Mediha Boran, and Oguz Tasdemir. "Acute renal failure following open heart surgery: risk factors and prognosis." Perfusion 20, no. 6 (December 2005): 317–22. http://dx.doi.org/10.1191/0267659105pf829oa.

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Background: Acute renal failure (ARF) development after cardiac surgery carries high mortality and morbidity. Methods: Out of 14 437 consecutive patients undergoing open-heart surgery between January 1991 and May 2001, 168 (1.16%) developed postoperative ARF mandating hemodialysis. Possible perioperative risk factors, and the prognosis of this dreadful, often fatal complication were investigated. Results: The mortality rate in this group was 79.7% (134 patients). The risk factors associated with postoperative ARF were advanced age (p-0.000), diabetes mellitus (p-0.000), hypertension (p-0.000), high preoperative serum creatinine levels (p-0.004), impaired left ventricular function (p-0.002), urgent operation (p-0.000) or reoperation (p-0.007), prolonged cardiopulmonary bypass (CPB) (p-0.000) and aortic cross-clamp (ACC) (p-0.000) periods, level of hypothermia (p-0.000), concomitant procedures (p-0.000), low cardiac output state (p-0.000), re-exploration for bleeding or pericardial tamponade (p-0.000), and deep sternal or systemic infection (p-0.000). Of those who could be discharged from hospital, renal functions were restored in 21 patients (12.5%); however, eight patients (4.7%) became hemodialysis dependent. The mean follow-up period was 5.79/3.2 years (range: 4 months to 13 years; a total of 195 patient-years), and 10-year survival was 58.69/10.2% in the discharged patients. Conclusions: ARF development after cardiac surgery often results in high morbidity and mortality. Recognizing risk factors permits the timely institution of proper treatment, which is the key to reducing untoward outcomes.
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Shinkai, Noriko, Yu Shomura, Yukikatsu Okada, and Matsuko Doi. "The Risk Factors of Surgical Site Infection after Valvular Heart Surgery." Japanese Journal of Cardiovascular Surgery 42, no. 2 (2013): 108–13. http://dx.doi.org/10.4326/jjcvs.42.108.

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21

Maleki, Majid, Arsha Karbassi, Feridoun Noohi, and Gholamreza Omrani. "Risk Factors and Outcome in Iranian Cardiac Surgery: Iranian Heart Score." American Heart Hospital Journal 5, no. 4 (September 2007): 223–27. http://dx.doi.org/10.1111/j.1541-9215.2007.07348.x.

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22

Mandell, M. Susan, Tamas Seres, JoAnn Lindenfeld, Scott W. Biggins, David Chascsa, Brian Ahlgren, Michael Wachs, and Kiran M. Bambha. "Risk Factors Associated With Acute Heart Failure During Liver Transplant Surgery." Transplantation 99, no. 4 (April 2015): 873–78. http://dx.doi.org/10.1097/tp.0000000000000387.

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23

Gupta, Punkaj, Mallikarjuna Rettiganti, Jeffrey M. Gossett, Justin C. Yeh, Howard E. Jeffries, Tom B. Rice, and Randall C. Wetzel. "Risk factors for mechanical ventilation and reintubation after pediatric heart surgery." Journal of Thoracic and Cardiovascular Surgery 151, no. 2 (February 2016): 451–58. http://dx.doi.org/10.1016/j.jtcvs.2015.09.080.

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24

Pasternack, Daniel M., Manal AlQahtani, Rafael Zonana Amkie, Lisa J. Sosa, Marcelle Reyes, and Jun Sasaki. "Risk factors and outcomes for hyperbilirubinaemia after heart surgery in children." Cardiology in the Young 30, no. 6 (May 5, 2020): 761–68. http://dx.doi.org/10.1017/s1047951120000967.

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AbstractIntroduction:Liver dysfunction, associated with morbidity and mortality, is common in patients with CHD. We investigate risk factors for and outcomes of hyperbilirubinaemia in neonates and infants after cardiac surgery.Materials and methods:In a retrospective analysis of neonates and infants undergoing cardiac surgery at our institution between January 2013 and December 2017, we identified those with post-operative conjugated hyperbilirubinaemia. We tested various demographic and surgical risk factors, and use of post-operative interventions, for an association with conjugated hyperbilirubinaemia. We also tested hyperbilirubinaemia for association with post-operative mortality and prolonged length of stay.Results:We identified 242 post-operative admissions, of which 45 (19%) had conjugated hyperbilirubinaemia. The average conjugated bilirubin level in this group was 2.0 mg/dl versus 0.3 mg/dl for peers without hyperbilirubinaemia. The post-operative use of both extracorporeal membrane oxygenation (OR 4.97, 95% CI 1.89–13.5, p = 0.001) and total parenteral nutrition (OR 2.98, 95% CI 1.34–7.17, p = 0.010) was associated with conjugated hyperbilirubinaemia. No demographic variable analysed was found to be a risk factor. Hyperbilirubinaemia was associated with higher odds of mortality (OR 3.74, 95% CI 2.69–13.8, p = 0.005) and prolonged length of stay (OR 2.87, 95% CI 2.02–7.97, p = 0.005), which were independent of other risk factors.Discussion:We identified the post-operative use of total parenteral nutrition and extracorporeal membrane oxygenation as risk factors for hyperbilirubinaemia. These patients were more likely to experience morbidity and mortality than control peers. As such, bilirubin may be marker for elevated risk of poor post-operative outcomes and should be more frequently measured after cardiac surgery.
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Benavidez, Oscar J., Kimberlee Gauvreau, Pedro Del Nido, Emile Bacha, and Kathy J. Jenkins. "Complications and Risk Factors for Mortality During Congenital Heart Surgery Admissions." Annals of Thoracic Surgery 84, no. 1 (July 2007): 147–55. http://dx.doi.org/10.1016/j.athoracsur.2007.02.048.

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Japaralieva, Aruke. "THE EFFECT OF BARIATRIC SURGERY ON RISK FACTORS FOR CARDIOVASCULAR DISEASES." Chronos 7, no. 8(70) (October 13, 2022): 11–12. http://dx.doi.org/10.52013/2658-7556-70-8-5.

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Obese patients have an increased prevalence of risk factors for cardiovascular disease (CVD), which are improved by bariatric surgery, but whether bariatric surgery reduces long-term cardiovascular events remains unclear. This study examines the impact of bariatric surgery on the reduction of cardiac risk factors, which, in turn, protects the heart from premature death.
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Mahdi, Aithoussa, Atmani Noureddine, Moutakiallah Younes, Bamous Mehdi, Abdou Abdessamad, Nya Fouad, Seghrouchni Aniss, et al. "Upper gastrointestinal bleeding after open heart surgery." Journal of Digestive Endoscopy 05, no. 03 (July 2014): 101–5. http://dx.doi.org/10.4103/0976-5042.147501.

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Abstract Objective: The occurrence of digestive complications especially upper gastrointestinal bleeding (UGIB) has increased after cardiac surgery. The aim of this study was to determine the incidence of UGIB and identify the independent risk factors. Materials and Methods: We retrospectively analyzed data of 1077 patients undergoing cardiopulmonary bypass (CPB) from 1994 to 2012 The group of patients with UGIB (n 1 = 20) was compared with the population group (n 2 = 1057). Demographic characteristics, therapeutic management, endoscopic findings, and outcomes were analyzed. Through a regression analysis we identified independent risk factors of UGIB. Results: The mean age of the group n 1 was 58.2 ± 12.4 years and 50.18 ± 13.5 years in the group n 2. UGIB occurred about 13 ± 5.5 days after cardiac surgery. Gastroduodenal ulcer was the most common etiology of hemorrhage (n = 13, 65%). Renal insufficiency, previous gastric ulcer, increased lactate concentration during CPB, prolonged mechanical ventilation, use of vasopressor drug and pulmonary infection was likely contributing factors in UGIB. Conclusion: UGIB following open cardiac surgery is most frequently secondary to gastroduodenal ulceration. Many determinant factors of bleeding are incriminated. Surgeons must be aware of these factors to avoid fatal complications.
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Chotisukarat, Haruthai, Phuping Akavipat, Pathomporn Suchartwatnachai, Pimwan Sookplung, and Jatuporn Eiamcharoenwit. "Incidence and Risk Factors for Perioperative Cardiovascular Complications in Spine Surgery." F1000Research 11 (March 17, 2022): 15. http://dx.doi.org/10.12688/f1000research.75245.2.

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Background: An increasing number of patients are opting for spine surgery despite the associated risk of cardiovascular complications. The evidence regarding the incidence and risk factors of cardiovascular complications in spine surgery is insufficient. Therefore, we aimed to determine the incidence and risk factors for cardiovascular complications that occur perioperatively in spine surgery. Methods: This retrospective study included all patients who underwent spine surgery between January 2018 and December 2019 at a single center. Demographic, clinical, and operative data were collected from electronic medical records. The incidence of perioperative cardiac complications was determined. Univariate and multivariate analyses were performed to identify risk factors for the development of perioperative cardiovascular complications in the participants. Results: Of the 1,002 eligible patients enrolled in the study, six developed cardiac complications. Acute myocardial infarction, cardiac arrest, and congestive heart failure occurred in one, two, and three patients, respectively. Risk factors for cardiovascular complications included scoliosis surgery (odds ratios (OR): 18.61; 95% confidence interval (CI): 1.346-257.35) and a history of congestive heart failure (OR: 120.97; 95% CI: 2.12-6898.80). Conclusion: The incidence of perioperative cardiovascular complications in patients who underwent spine surgery was 0.6%. High-risk patients should be closely monitored optimally managed throughout the perioperative period.
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Stepin, A. V. "Impact of some intraoperative factors on wound infection in cardiac surgery." Ural Medical Journal 20, no. 1 (July 12, 2021): 36–43. http://dx.doi.org/10.52420/2071-5943-2021-20-1-36-43.

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Relevanc. Surgical Site Infection (SSI) after open heart surgery is a significant problem in clinical, social, and economic aspect which causes the need to identification of the preferred procedures for successful prevention of the SSI.Objectives. To determine risk of the SSI in cardiac surgery depending on complexity of intervention, using of cardiopulmonary bypass (CBP) and use of both internal mammary arteries (IMA).Methods. Prospective observations study from 2010 to 2019 in cardiac surgery department of the Ural Institute of Cardiology, where in total 4993 open heart surgery procedures were consecutively performed. All SSI cases were recorded up to 90 days after surgery. The analysis was performed to identify risk of cardiopulmonary bypass (CPB), bilateral IMA grafting and combined procedures on the risk of the postoperative wound infection.Results. During the investigation period, total 220 cases of the SSI (4,5%) have been registered of the 4993 patients undergoing open heart surgery. It included 42 cases of deep sternal infection (0,9%) and 178 cases of superficial infection (3,6%). The main pathogen identified was Staphylococcus epidermidis (56,4%). During the hospital period, 151 cases (66,5%) of SSI have been detected, with the median time to detection of the complication 6 days. The relative mortality risk in deep sternal infection group was 4,4 times higher than in the group without SSI (HR 4,6, 95 % CI 1,5-13,9, p=0,003624). CABG increases the relative risk of SSI in compare with non-CABG procedures (OR 3,086169; 95%CI 1,281 – 7,437), while the complexity of the operation (combined versus isolated interventions) does not significantly increase the risk (OR 0.972283; 95% CI: 0.696 - 1.359). The incidence of SSI in the group of in situ BIMA grafting was 8.8%, significantly increasing the likelihood of the SSI in compare to those with SIMA (OR 2.167983, 95% CI 1.463 - 3.212; p =0,000057). CBP significantly increases the risk of postoperative wound infections (OR 1.523890, 95% CI 1.149 - 2.022, p = 0.001742).Conclusions. Refusal of cardiopulmonary bypass, simultaneous procedures and bilateral coronary artery bypass does not allow completely to avoid postoperative wound infections. Nevertheless, the technical features of the preparations and use of grafts, including skeletonization, prevention of coagulation and the preference for sequential composite CABG, can reduce the risk associated with the type of the open heart surgery.
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Omoto, Tadashi, Kazutomo Minami, Dietmar Böthig, Ulrich Schütt, Gero Tenderich, Stephan Wlost, and Reiner Körfer. "Risk Factor Analysis of Orthotopic Heart Transplantation." Asian Cardiovascular and Thoracic Annals 11, no. 1 (March 2003): 33–36. http://dx.doi.org/10.1177/021849230301100109.

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From March 1989 to December 1999, 1,013 heart transplantations were carried out in this center. Univariate analysis of potential risk factors for early death was followed by stepwise logistic regression to determine independent risk factors. Long-term results were assessed by the Kaplan-Meier method. Multivariate comparisons of long-term results were performed using Cox's proportional hazards model. Early mortality was 8.6%. Actuarial survival was 78.1%, 69.4%, and 53.1% at 1, 5, and 10 years, respectively. Mean total ischemic time was 194 minutes. Independent risk factors of early mortality were female recipient, donor age over 50 years, and ischemic heart disease in the recipient. The precise mechanism of the increased early mortality in female recipients should be studied in the future. Although older donor age was a predictor of early mortality, because of the donor shortage, older hearts should not be excluded from the donor pool. Survival was better in patients with dilative cardiomyopathy than in those with ischemic heart disease.
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31

Lastovka, Vasily A., Rustem F. Tepaev, Olga B. Gordeeva, Anuar R. Bidzhiev, and Elena A. Fedyaeva. "Clinical Risk Factors of Thrombosis in Children after Congenial Heart Diseases Management." Pediatric pharmacology 17, no. 5 (November 23, 2020): 424–28. http://dx.doi.org/10.15690/pf.v17i5.2161.

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Background. Development of thrombotic complications in the postoperative period worsens the course of the disease and increases mortality of children operated for congenital heart diseases (CDC). There is limited data on clinical risk factors of thrombosis after CDCs surgical correction in modern literature. In our opinion, there are several promising factors that have not been studied as predictors of thrombosis in children with CDCs. Aim of the study is to analyze possible effect of patient clinical characteristics on development of thrombotic complications in infants after surgical treatment of CDC. Methods. We have studied data of 156 children aged from birth to 11 months 29 days (median age — 5 months) with CDCs operated under artificial circulation. Following indexes were studied in all patients: age, surgical risk according to RACHS-1 (Risk adjustment for congenital heart surgery), anesthesia duration, surgery duration, aortic cross-clamping time, artificial circulation duration, gestation period, body weight and height at the time of surgery. Results. Thrombosis was diagnosed in 44 patients (28.2%) in the postoperative period. Thromboses of various localizations were found during the patients’ examination: cerebral, intracardiac, limbs vessels, etc. It was revealed that thrombosis detection in patients with RACHS-1 >3 has increased in 2.84 times (95% CI: 1.36-5.92), at anesthesia duration >220 minutes — in 2.64 times (95% CI: 1.15-6.05), at surgery duration >150 minutes — in 3.36 times (95% MD: 1.51-7.5), at aortic cross-clamping time >32 minutes – in 3.23 times (95% CI: 1.45-7.32), at artificial circulation duration >70 minutes — in 3.43 times (95% MD: 1.6-7.34), with gestation period less than 39 weeks — in 2.44 times (95% CI: 1.18-5.03), with child’s weight less than 5.000 grams – in 4.3 times (95% CI: 2.02-9.15), with child’s height less than 60 centimeters — in 4.57 times (95% CI: 2.15-9.73), and at the age less than 3 months old — in 2.31 times (95% CI: 1.08-4.92). Conclusion. RACHS-1 >3, anesthesia duration >220 minutes, surgery duration >150 minutes, aortic cross-clamping time >32 minutes, artificial circulation duration >70 minutes, gestation period less than 39 weeks, weight at the time of surgery less than 5000 grams, height at the time of surgery less than 60 centimeters, and age under 3 months increases the risk of thrombotic complications in postoperative period.
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Chotisukarat, Haruthai, Phuping Akavipat, Pathomporn Suchartwatnachai, Pimwan Sookplung, and Jatuporn Eiamcharoenwit. "Incidence of and Risk Factors for Perioperative Cardiovascular Complications in Spine Surgery." F1000Research 11 (January 7, 2022): 15. http://dx.doi.org/10.12688/f1000research.75245.1.

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Background: An increasing number of patients are opting for spine surgery despite the associated risk of cardiovascular complications. The evidence regarding the incidence and risk factors of cardiovascular complications in spine surgery is insufficient. Therefore, we aimed to determine the incidence and risk factors for cardiovascular complications that occur perioperatively in spine surgery. Methods: This retrospective study included all patients who underwent spine surgery between January 2018 and December 2019 at a single center. Demographic, clinical, and operative data were collected from electronic medical records. The incidence of perioperative cardiac complications was determined. Univariate and multivariate analyses were performed to identify risk factors for the development of perioperative cardiovascular complications in the participants. Results: Of the 1,002 eligible patients enrolled in the study, six developed cardiac complications. Acute myocardial infarction, cardiac arrest, and congestive heart failure occurred in one, two, and three patients, respectively. Risk factors for cardiovascular complications included scoliosis surgery (relative risk: RR, 18.61; 95% confidence interval (CI): 1.346-257.35) and a history of congestive heart failure (RR, 120.97; 95% CI: 2.12-6898.80). Conclusion: The incidence of perioperative cardiovascular complications in patients who underwent spine surgery was 0.6%. High-risk patients should be closely monitored optimally managed throughout the perioperative period.
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Zhang, Guowei, Naishi Wu, Hongyu Liu, Hang Lv, Zhifa Yao, and Junquan Li. "Case control study of gastrointestinal complications after cardiopulmonary bypass heart surgery." Perfusion 24, no. 3 (May 2009): 173–78. http://dx.doi.org/10.1177/0267659109346665.

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Background: Gastrointestinal complications (GIC) after cardiopulmonary bypass (CPB) surgery are rare, but, nevertheless, extremely dangerous.The identification of risks for GIC may be helpful in planning appropriate perioperative management strategies. The aim of the present study was to analyze perioperative factors of GIC in patients undergoing CPB surgery. Methods: We retrospectively analysed 206 patients who underwent GIC after cardiopulmonary bypass surgery from 2000 to 2007 and compared them with 206 matched control patients (matched for surgery, temperature, hemodilution and date). Univariate analysis and multiple logistic regression analysis were performed on 12 risk factors. Result: Sex and types of cardioplegia perfusate did not significantly influence the GIC after CPB surgery. Multiple logistic regression revealed that CPB time, preoperative serum creatinine (PSC) ≥ 179 mg/dL, emergency surgery, perfusion pressure ≤40mmHg, low cardiac output syndrome (LCOS), age ≥ 61, mechanical ventilation ≥96 h, New York Heart Association (NYHA) class III and IV were predictors of the occurrence of GIC after CPB surgery. Perfusion pressure and aprotinin administration were protective factors. Conclusion: Gastrointestinal complications after CPB surgery could be predictive in the presence of the above risk factors. This study suggests that GIC can be reduced by maintenance of higher perfusion pressure and shortening the time on CPB and ventilation.
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Belanger, Michael, Luke Tan, and Carin Wittnich. "Does young age really put the heart at risk?" Canadian Journal of Physiology and Pharmacology 95, no. 10 (October 2017): 1177–82. http://dx.doi.org/10.1139/cjpp-2017-0072.

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Despite significant advances in the management and treatment of heart disease in children, there continue to be patients who have worse outcomes than might be expected. A number of risk factors that could be responsible have been identified. Evidence-based findings will be reviewed, including whether young age and (or) reduced body weight exacerbate these responses. For example, newborn children undergoing congenital cardiac surgery are known to have worse outcomes than older children. Evidence exists that newborn hearts do not tolerate ischemia as well as adult hearts, developing irreversible injury sooner and exhibiting at-risk metabolic profiles. As well, in response to the administration of heparin, elevations in free fatty acids occur during congenital heart surgery in children, which can have detrimental effects on the heart. Furthermore, myocardial energetic state has also been suggested to impact outcomes. Unfavourable energetic profiles were correlated to lower body weights in the same age healthy newborn piglet model. Newborn children suffering from congenital heart disease, with lower body weights, also had lower myocardial energetic state and this correlated with longer postoperative ventilatory support as well as a trend to longer intensive care unit stay. These findings imply that unfavourable myocardial metabolic profiles could contribute to postoperative complications.
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Muthialu, Nagarajan. "Risk Factors and Outcome of Acute Kidney Injury After Congenital Heart Surgery." Indian Journal of Critical Care Medicine 22, no. 3 (2018): 198–99. http://dx.doi.org/10.4103/ijccm.ijccm_508_17.

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36

Seguin, Jade, Benjamin Albright, Laura Vertullo, Pamela Lai, Adrian Dancea, Pierre-Luc Bernier, Christo I. Tchervenkov, et al. "Extent, Risk Factors, and Outcome of Fluid Overload After Pediatric Heart Surgery*." Critical Care Medicine 42, no. 12 (December 2014): 2591–99. http://dx.doi.org/10.1097/ccm.0000000000000517.

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ENGER, T. B., H. PLEYM, R. STENSETH, A. WAHBA, and V. VIDEM. "Genetic and clinical risk factors for fluid overload following open-heart surgery." Acta Anaesthesiologica Scandinavica 58, no. 5 (March 14, 2014): 539–48. http://dx.doi.org/10.1111/aas.12310.

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38

Kim, Yuli Y., Kimberlee Gauvreau, Emile A. Bacha, Michael J. Landzberg, and Oscar J. Benavidez. "Risk Factors for Death After Adult Congenital Heart Surgery in Pediatric Hospitals." Circulation: Cardiovascular Quality and Outcomes 4, no. 4 (July 2011): 433–39. http://dx.doi.org/10.1161/circoutcomes.110.958256.

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39

Martinez, E. A. "Risk Factors for Death After Adult Congenital Heart Surgery in Pediatric Hospitals." Yearbook of Critical Care Medicine 2012 (January 2012): 20–22. http://dx.doi.org/10.1016/j.yccm.2012.02.003.

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40

Kim, Yuli Y., Kimberlee Gauvreau, Emile Bacha, Michael J. Landzberg, and Oscar J. Benavidez. "RISK FACTORS FOR DEATH FOLLOWING ADULT CONGENITAL HEART SURGERY IN PEDIATRIC HOSPITALS." Journal of the American College of Cardiology 55, no. 10 (March 2010): A41.E394. http://dx.doi.org/10.1016/s0735-1097(10)60395-6.

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41

Nishi, Hiroyuki, Taichi Sakaguchi, Shigeru Miyagawa, Yasushi Yoshikawa, Satsuki Fukushima, Shunsuke Saito, Takayoshi Ueno, Toru Kuratani, and Yoshiki Sawa. "Frequency, Risk Factors and Prognosis of Postoperative Hyperbilirubinemia after Heart Valve Surgery." Cardiology 122, no. 1 (2012): 12–19. http://dx.doi.org/10.1159/000338142.

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42

Hortal, Javier, Maddalena Giannella, Maria Jesús Pérez, José Maria Barrio, Manuel Desco, Emilio Bouza, and Patricia Muñoz. "Incidence and risk factors for ventilator-associated pneumonia after major heart surgery." Intensive Care Medicine 35, no. 9 (June 26, 2009): 1518–25. http://dx.doi.org/10.1007/s00134-009-1523-3.

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43

Lai, Yi Chun, and Yik Weng Yew. "Psoriasis as an Independent Risk Factor for Cardiovascular Disease." Journal of Cutaneous Medicine and Surgery 20, no. 4 (August 27, 2015): 327–33. http://dx.doi.org/10.1177/1203475415602842.

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Background: Psoriasis is known to be associated with metabolic syndrome, a well-established risk factor for ischemic heart disease and stroke. Emerging evidence indicates that psoriasis is an independent risk factor for cardiovascular disease and stroke. Objective: To evaluate whether psoriasis is independently associated with myocardial infarction (MI), ischemic heart disease (MI, angina pectoris, or coronary heart disease), and stroke, we conducted a cross-sectional study using the US National Health and Nutrition Examination Survey (NHANES) database. Methods: Data on clinical history of psoriasis, MI, angina pectoris, coronary heart disease, and stroke from the questionnaire as well as laboratory parameters on serum lipid and uric acid levels in the cycle years 2003-2006 and 2009-2012 were analyzed. Multivariate analysis with logistic regression modelling was performed with the aforementioned cardiovascular events or stroke as the dependent variables and with risk factors such as age, gender, ethnic group, current smoking status, alcohol consumption, metabolic syndrome, hyperuricemia, and psoriasis as independent variables. Results: There were 520 cases of psoriasis, and 108 of them had metabolic syndrome (20.8%). Well-established cardiovascular risk factors such as age, gender, ethnic group, smoking, alcohol consumption, metabolic syndrome, and hyperuricemia were also found to have significant associations with MI and ischemic heart disease (all P values <.001). Psoriatic patients were at significantly higher risks of developing MI (odds ratio [OR] 2.24; 95% CI: 1.27-3.95; P = .005) and ischemic heart disease (OR 1.90; 95% CI: 1.18-3.05; P = .008), but not stroke (OR 1.01; 95% CI: 0.48-2.16; P = .744), after adjustment was made for major cardiovascular risk factors. Conclusion: This study provides epidemiological evidence that psoriasis may be independently associated with the development of MI and ischemic heart disease. Physicians should be cognizant of any underlying cardiovascular risk factors, especially among psoriatic patients with metabolic syndrome, and manage them according to national guidelines.
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44

Preveden, Mihaela, Andrej Preveden, Ranko Zdravkovic, Nina Dracina, Vladislava Djoric, and Milanka Tatic. "Delirium in cardiac surgery - risk factors and prevention." Medical review 75, no. 3-4 (2022): 133–37. http://dx.doi.org/10.2298/mpns2204133p.

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Introduction. Delirium is defined as an acute change in mental status that leads to disturbance in perception, thinking, memory, attention, emotional status, as well as sleep rhythm disorders and is most often reversible. Postoperative delirium is an acute mental disorder that develops after cardiovascular surgery with an incidence of 20 - 50% of operated patients. This complication is associated with a longer hospitalization, longer stay in the intensive care unit, as well as increased morbidity and mortality. Risk Factors. The risk factors are divided into preoperative, intraoperative and postoperative. The most common preoperative risk factors are older age, stenosis of the carotid arteries, previous cerebral diseases, depression, diabetes, hypertension, low ejection fraction of the left ventricle, as well as heart rhythm disorders. Intraoperative risk factors include the type of surgery, type of anesthesia, duration of extracorporeal circulation, and duration of aortic clamp. The most important postoperative risk factors include the use of psychoactive drugs, prolonged pain, the use of opioid drugs, duration of mechanical ventilation, and the length of stay in the intensive care unit. Prevention. Prevention is a very important aspect that is most often focused on intraoperative and postoperative precipitating factors. Preventive treatment includes pharmacological and non-pharmacological methods. The main recommendation refers to avoiding routine use of antipsychotics. Conclusion. Continuous infusion of dexmedetomidine compared to propofol reduces the incidence of postoperative delirium. Nonpharmacological approach consists of a series of procedures that are carried out postoperatively, such as the protocol that includes monitoring of Awakening, Breathing, Coordination, Delirium, Early mobility, and Family engagement.
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Ringaitienė, Donata, Dalia Gineitytė, Vaidas Vicka, Tadas Žvirblis, Jūratė Šipylaitė, Algimantas Irnius, and Juozas Ivaškevičius. "Preoperative risk factors of malnutrition for cardiac surgery patients." Acta medica Lituanica 23, no. 2 (July 31, 2016): 99–109. http://dx.doi.org/10.6001/actamedica.v23i2.3326.

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Background. Malnutrition (MN) is prevalent in cardiac surgery, but there are no specific preoperative risk factors of MN. The aim of this study is to assess the clinically relevant risk factors of MN for cardiac surgery patients. Materials and methods. The nutritional state of the patients was evaluated one day prior to surgery using a bioelectrical impedance analysis phase angle (PA). Two groups of patients were generated according to low PA: malnourished and well nourished. Risk factors of MN were divided into three clinically relevant groups: psychosocial and lifestyle factors, laboratory findings and disease-associated factors. Variables in each different group were entered into separate multivariate logistic regression models. Results. A total of 712 patients were included in the study. The majority of them were 65-year old men after a CABG procedure. Low PA was present in 22.9% (163) of patients. The analysis of disease-related factors of MN revealed the importance of heart functions (NYHA IV class OR: 3.073, CI95%: 1.416–6.668, p = 0.007), valve pathology (OR: 1.825, CI95%: 1.182–2.819, p = 0.007), renal insufficiency (OR: 4.091, CI95%: 1.995–8.389, p
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Pérez-Miralles, F., J. C. Sánchez-Manso, L. Almenar-Bonet, T. Sevilla-Mantecón, L. Martı́nez-Dolz, and J. J. Vílchez-Padilla. "Incidence of and Risk Factors for Neurologic Complications After Heart Transplantation." Transplantation Proceedings 37, no. 9 (November 2005): 4067–70. http://dx.doi.org/10.1016/j.transproceed.2005.09.162.

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47

Molina, B. D., M. G. C. Leiro, L. A. Pulpón, S. Mirabet, J. F. Yañez, L. A. Bonet, F. G. Vilchez, et al. "Incidence and Risk Factors for Nonmelanoma Skin Cancer After Heart Transplantation." Transplantation Proceedings 42, no. 8 (October 2010): 3001–5. http://dx.doi.org/10.1016/j.transproceed.2010.08.003.

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48

Ghosh, Suman, Joseph Philip, Nikita Patel, Jennifer Munoz-Pareja, Dalia Lopez-Colon, Mark Bleiweis, and Steven Parrish Winesett. "Risk Factors for Seizures and Epilepsy in Children With Congenital Heart Disease." Journal of Child Neurology 35, no. 7 (February 27, 2020): 442–47. http://dx.doi.org/10.1177/0883073820904912.

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Objectives: To identify potential risk factors for pre- and postoperative seizures and epilepsy in children with congenital heart disease. Methods: Retrospective cohort study of neonates and infants <3 months of age with congenital heart disease who underwent cardiopulmonary bypass from November 24, 2006, until June 1, 2015. Children with seizures were classified based on time of occurrence into early preoperative, early postoperative, and late postoperative. Children with recurring seizures 30 days after cardiac surgery met criteria for epilepsy. Results: 247 patients completed follow-up; 2.4% had seizures early preoperation and 1.6% early postoperation. Late postoperative epilepsy occurred in 5.3% of the cohort. The majority of seizures in the late postoperative epilepsy group started after 1 year of age (mean 1.53 years, range = 0.18-4.7 years). One of the 13 patients with epilepsy had a seizure during their intensive care unit hospitalization. Potential risk factors for seizures included brain injury ( P < .001), high-risk surgery (Society of Thoracic Surgeons-European Association for Cardio-Thoracic Surgery score ≥3, P = .024), and low birth weight ( P < .04). Infants with stroke were more likely to develop epilepsy ( P = .04). Presence of seizures was associated with increased length of stay ( P < .001). Conclusions: Our study suggests an association between children with congenital heart disease diagnosed with stroke in the neonatal/infancy period and the development of epilepsy. These children may not have prior early pre- and postoperative seizures. Risk factors for seizures include brain injury, high-risk surgery, and lower birth weight. Seizures were associated with an increased length of stay but did not necessarily lead to subsequent epilepsy.
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Spiropoulou, Eleni, George Samanidis, Meletios Kanakis, and Ioannis Nenekidis. "Risk Factors for Acute Postoperative Delirium in Cardiac Surgery Patients >65 Years Old." Journal of Personalized Medicine 12, no. 9 (September 18, 2022): 1529. http://dx.doi.org/10.3390/jpm12091529.

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Background: Acute postoperative delirium is the most common neuropsychiatric disorder in cardiac surgery patients in the intensive care unit (ICU). The purpose of this study was to evaluate the possible risk factors of postoperative delirium (POD) for cardiac surgery patients in the ICU. Materials and Methods: The study population was composed of 86 cardiac surgery patients managed postoperatively in the cardiac surgery ICU. Presence of POD in patients was evaluated by the CAM-ICU scale. Results: According to the CAM-ICU scale, 22 (25.6%) patients presented POD; history of smoking, alcohol use, COPD, and preoperative permanent atrial fibrillation were associated with POD (for all, p < 0.05). The type of cardiac surgery operations, type of analgesia, and red blood cell transfusion in the ICU were not associated with POD (p > 0.05), while cardiac arrhythmia in the ICU, hypoxemia in the ICU after extubation (pO2 < 60 mmHg), and heart rate after extubation were predisposing factors for POD (for all, p < 0.05). Multivariable logistic regression analysis (adjusted to risk factors) showed that hypoxemia after extubation (OR = 20.6; 95%CI: 2.82–150), heart rate after extubation (OR = 0.95; 95% CI: 0.92–0.98), and alcohol use (OR = 74.3; 95%CI: 6.41–861) were predictive factors for acute postoperative delirium (for all, p < 0.05). Conclusion: Alcohol use and respiratory dysfunction before and after heart operation were associated with acute postoperative delirium in cardiac surgery ICU patients.
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Spaniol, SE, EF Bond, GL Brengelmann, M. Savage, and RS Pozos. "Shivering following cardiac surgery: predictive factors, consequences, and characteristics." American Journal of Critical Care 3, no. 5 (September 1, 1994): 356–67. http://dx.doi.org/10.4037/ajcc1994.3.5.356.

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BACKGROUND: Shivering is common after cardiac surgery and may evoke harmful hemodynamic changes. Neither those changes nor factors increasing probability of shivering are well defined. OBJECTIVES: (1) To identify factors linked with risk of shivering by comparing age, weight, body surface area, gender, intraoperative details, anesthetics, postoperative temperatures, hemodynamics, and therapeutics in shivering vs nonshivering patients. (2) To describe temperatures, hemodynamics, therapeutics, myocardial oxygen consumption correlates (rate-pressure product, heart rate, systemic vascular resistance) in shivering and nonshivering groups, and shivering and nonshivering periods. (3) To characterize the electromyogram to determine whether the tremor is cold-induced. METHODS: A descriptive design with a time series component was used to study a convenience sample of 10 shivering and 10 nonshivering adults for 4 hours during early recovery from cardiac surgery. Pulmonary artery and skin (facial, calf, trunk) temperature were measured every 60 seconds; heart rate and arterial pressure, every 15 minutes; cardiac output, 3 times. Electromyogram was recorded intermittently. Medications and treatments were noted. RESULTS: Lower skin temperature was significantly related to shivering risk. Heart rate was significantly higher initially in shiverers and remained higher by 13.6 beats per minute. Significantly more nitroprusside was used to control arterial pressure before than after shivering. No significant differences were noted between groups in core temperature, age, weight, body surface area, anesthesia type, intraoperative temperature; or surgery, circulatory bypass, or cardiac cross-clamp duration. The electromyogram pattern during shivering was typical of that produced by cold. CONCLUSIONS: These results suggest that true shivering occurs after cardiac surgery. Skin, but not core, temperature and elevated heart rate predict shivering. Shivering may be more likely in hemodynamically unstable patients.
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