Academic literature on the topic 'Heart formation'

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Journal articles on the topic "Heart formation"

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Marecki, Bogusław. "The formation of heart-proportion in fetal ontogenesis." Zeitschrift für Morphologie und Anthropologie 79, no. 2 (October 30, 1992): 197–202. http://dx.doi.org/10.1127/zma/79/1992/197.

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Pasterkamp, G. "The erythrocyte: a new player in atheromatous core formation." Heart 88, no. 2 (August 1, 2002): 115–16. http://dx.doi.org/10.1136/heart.88.2.115.

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Lasater, Phillip M. "The Heart of Self Formation." Dead Sea Discoveries 28, no. 3 (October 6, 2021): 367–95. http://dx.doi.org/10.1163/15685179-bja10025.

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Abstract This article discusses the “heart” as part of the terminology for selfhood in ancient Jewish literature. After discussing a couple of criticisms of studies of the self and showing how these criticisms fail to persuade, the paper examines a range of texts in the Hebrew Bible, the Dead Sea Scrolls, and beyond for conceptions of the moral self. Special attention is given to the legal S tradition in the Scrolls as a fruitful illustration of how the self and law are recurring conceptual companions. In this legal tradition, a universalizing conception of selfhood and agency is rooted in local, practical concerns of a community.
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CRACOWSKI, J. L. "Increased formation of F2-isoprostanes in patients with severe heart failure." Heart 84, no. 4 (October 1, 2000): 439–40. http://dx.doi.org/10.1136/heart.84.4.439.

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Weidenbach, M. "Infective endocarditis with progressive periaortal abscess formation in a previously healthy girl." Heart 89, no. 7 (July 1, 2003): 730. http://dx.doi.org/10.1136/heart.89.7.730.

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Moorman, A. "DEVELOPMENT OF THE HEART: (1) FORMATION OF THE CARDIAC CHAMBERS AND ARTERIAL TRUNKS." Heart 89, no. 7 (July 1, 2003): 806–14. http://dx.doi.org/10.1136/heart.89.7.806.

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Camacho, J. A., C. J. Peterson, G. J. White, and H. E. Morgan. "Accelerated ribosome formation and growth in neonatal pig hearts." American Journal of Physiology-Cell Physiology 258, no. 1 (January 1, 1990): C86—C91. http://dx.doi.org/10.1152/ajpcell.1990.258.1.c86.

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Rapid growth (5 mg dry heart/h) of the left ventricular free wall (LVFW) in the newborn pig heart accompanied by lack of growth of the right ventricular free wall (RVFW) represents a unique natural model of cardiac enlargement that is free of pathophysiological influences. By 3 days of life, LVFW was 71% larger than at 4 h of age. Rates of protein synthesis were measured during perfusion of isolated pig hearts with bicarbonate buffer containing glucose, lactate, insulin, and plasma concentrations of amino acids of an aortic pressure of 60 mmHg. In hearts from pigs that were 18 h of age, rates of protein synthesis were the same in RVFW and LVFW, but in 2-day-old pigs the rate was 52% greater in LVFW than RVFW. During the first 3 days of life, RNA content (mg/g) increased 3.4-fold faster in LVFW than RVFW. When RNA content was expressed per total heart portion, the increase was 7.9-fold greater. Because approximately 85% of total RNA is rRNA, these values indicated much more rapid formation of ribosomes in the LVFW than RVFW. When ribosome formation was measured in vitro in hearts from 48-h-old pigs, rates of formation were 39% greater in LVFW than RVFW, and at 18 h of age, ribosome formation was 40% faster in LVFW than RVFW. These findings indicated that formation of new ribosome preceded accelerated synthesis of total heart proteins. These findings indicated that rapid growth of LVFW compared with no growth of RVFW was associated with a 67% faster rate of ribosome formation and a 32% greater rate of protein synthesis.
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Heesch, C. M. "Cocaine activates platelets and increases the formation of circulating platelet containing microaggregates in humans." Heart 83, no. 6 (June 1, 2000): 688–95. http://dx.doi.org/10.1136/heart.83.6.688.

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Stainier, Didier Y. R. "Zebrafish genetics and vertebrate heart formation." Nature Reviews Genetics 2, no. 1 (January 2001): 39–48. http://dx.doi.org/10.1038/35047564.

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Roth, M., O. Reuthebuch, W. P. Klövekorn, and E. P. Bauer. "Thrombus formation of the right heart." European Journal of Cardio-Thoracic Surgery 13, no. 2 (February 1998): 216–17. http://dx.doi.org/10.1016/s1010-7940(97)00307-2.

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Dissertations / Theses on the topic "Heart formation"

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Vos, Marc Adriaan. "New observations to identify abnormal impulse formation in the intact heart." Maastricht : Maastricht : Datawyse ; University Library, Maastricht University [Host], 1989. http://arno.unimaas.nl/show.cgi?fid=5552.

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Song, Yuntao. "Epigenetic repression of retinoic acid responsive genes for cardiac outflow tract formation." University of Cincinnati / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1563295948947138.

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Thompson, Rosemary. "Some elements of a formation program for the religious of the Sacred Heart." Theological Research Exchange Network (TREN), 1996. http://www.tren.com.

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Caporilli, Simona. "Investigating the mechanisms of cardiac patterning and morphogenesis using a heart formation assay." Thesis, Cardiff University, 2010. http://orca.cf.ac.uk/54174/.

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Using Xenopus laevis embryos, the aim of this project is to establish a new experimental model to help understand the mechanism that regulates cardiac cell diversification and heart morphogenesis. In order to achieve these goals we use two assays. The cardiogenesis assay involves the use of animal cap explants excised from the animal pole of blastua embryos. Here it is shown that GATA-4 reliably induces the expression of ventricular and proepicardial markers, providing an assay to study the mechanisms of cardiac cell fate diversification. However, cardiomyocytes generated in animal pole explants do not undergo significant morphogenesis and physiological maturation. In order to study these later aspects of heart development we required a different assay to generate a structure similar to the heart. Using GATA-4 injected AC explants transplanted into host embryos we obtained secondary beating hearts in which regionally restricted cardiac gene expression was observed in addition to growth and a limited degree of morphogenesis. We demonstrated that the host plays an essential role as it provides a wide range of permissive regions which allow the development of the SH. Moreover, we also showed that the competence to generate a secondary heart is lost in reaggregates transplanted at stage 28. The host cells however do not contribute to the SH indicating that the role of the host is providing signals which allow the development of the SH.
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Donaldson, W. Steven. "The sedimentology, stratigraphy and diagenesis of the Upper Cretaceous Bad Heart Formation, NW Alberta." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1997. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape11/PQDD_0004/NQ40253.pdf.

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Sneesby, Kyra, and n/a. "Gene Expression in Embryonic Chick Heart Development." Griffith University. School of Biomolecular and Biomedical Science, 2003. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20030924.153514.

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Establishment of the biochemical and molecular nature of cardiac development is essential for us to understand the relationship between genetic and morphological aspects of heart formation. The molecular mechanisms that underly heart development are still not clearly defined. To address this issue we have used two approaches to identify genes involved in early chick cardiac development. Differential display previously conducted in our laboratory led to the identification of two gene fragments differentially expressed in the heart that are further described in this thesis. The full-length cDNA sequence of both eukaryotic translation initiation factor-2b (eIF-2b) and NADH cytochrome b5 reductase (b5R) were isolated using library screening. The upreglation of these genes during heart development is expected given the heart is the first functional organ to form in vertebrates and protein synthesis and cell metabolism at this stage of development is maximal. Limitations in the differential display approach led to the development and optimisation of a subtractive hybridisation approach for use with small amounts of cells or tissue. To focus on cardiac gene expression during the initial phases of heart development, subtractive hybridization was performed between the cardiogenic lateral plate mesoderm of Hamburger and Hamilton stage 4 embryos and the heart primordia of stage 9 embryos. Of the 87 independent clones identified by this procedure, 59 matched known sequences with high homology, 25 matched unknown expressed sequence tag (EST) sequences with high homology, and 3 did not match any known sequence on the database. Known genes isolated included those involved in transcription, translation, cell signalling, RNA processing, and energy production. Two of these genes, high mobility group phosphoprotein A2 (HMGA2) and C1-20C, an unknown gene, were chosen for further characterisation. The role of each gene in early chick heart development and indeed development in general, was addressed using techniques such as in situ hybridisation, transfection analysis, in ovo electroporation and RNAi. HMGA2 is a nuclear phosphoprotein commonly referred to as an architectural transcription factor due to its ability to modulate DNA conformation. In keeping with this function, HMGA2/GFP fusion protein was shown to localise to the nucleus and in particular, the nucleolus. In situ hybridisation analysis suggested a role for HMGA2 in heart and somite development. HMGA2 expression was first detected at HH stage 5 in the lateral plate mesoderm, a region synonymous with cells specified to the cardiac fate. HMGA2 was also strongly expressed in the presomitic segmental plate mesoderm and as somites developed from the segmental plate mesoderm, the expression of HMGA2 showed an increasingly more restricted domain corresponding to the level of maturation of the somite. Restriction of HMGA2 expression was first detected in the dorsal region of the epithelial somite, then the dorsomedial lip of the dermomyotome, and finally the migrating epaxial myotome cells. The novel intronless gene, C1-20C, predicts a protein of 148 amino acids containing a putative zinc finger binding domain and prenyl binding motif. Zinc binding assays showed that the zinc finger domain of C1-20C/MBP fusion protein bound over six times the quantity of zinc compared to MBP alone, although not in a 1:1 stoichiometric molar ratio. C1-20C/GFP fusion protein was shown to localise to as yet unidentified intracellular cytoplasmic vesicular compartments. These compartments did not colocalise with the endosome/lysosome pathway, aparently ruling out a role for C1-20C in protein trafficking, recycling or degradation. Expression of C1-20C in the chick embryo suggests a possible role in heart and notochord development and preliminary results using siRNA suggest that C1-20C is involved in normal heart looping.
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Sneesby, Kyra. "Gene Expression in Embryonic Chick Heart Development." Thesis, Griffith University, 2003. http://hdl.handle.net/10072/367647.

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Establishment of the biochemical and molecular nature of cardiac development is essential for us to understand the relationship between genetic and morphological aspects of heart formation. The molecular mechanisms that underly heart development are still not clearly defined. To address this issue we have used two approaches to identify genes involved in early chick cardiac development. Differential display previously conducted in our laboratory led to the identification of two gene fragments differentially expressed in the heart that are further described in this thesis. The full-length cDNA sequence of both eukaryotic translation initiation factor-2b (eIF-2b) and NADH cytochrome b5 reductase (b5R) were isolated using library screening. The upreglation of these genes during heart development is expected given the heart is the first functional organ to form in vertebrates and protein synthesis and cell metabolism at this stage of development is maximal. Limitations in the differential display approach led to the development and optimisation of a subtractive hybridisation approach for use with small amounts of cells or tissue. To focus on cardiac gene expression during the initial phases of heart development, subtractive hybridization was performed between the cardiogenic lateral plate mesoderm of Hamburger and Hamilton stage 4 embryos and the heart primordia of stage 9 embryos. Of the 87 independent clones identified by this procedure, 59 matched known sequences with high homology, 25 matched unknown expressed sequence tag (EST) sequences with high homology, and 3 did not match any known sequence on the database. Known genes isolated included those involved in transcription, translation, cell signalling, RNA processing, and energy production. Two of these genes, high mobility group phosphoprotein A2 (HMGA2) and C1-20C, an unknown gene, were chosen for further characterisation. The role of each gene in early chick heart development and indeed development in general, was addressed using techniques such as in situ hybridisation, transfection analysis, in ovo electroporation and RNAi. HMGA2 is a nuclear phosphoprotein commonly referred to as an architectural transcription factor due to its ability to modulate DNA conformation. In keeping with this function, HMGA2/GFP fusion protein was shown to localise to the nucleus and in particular, the nucleolus. In situ hybridisation analysis suggested a role for HMGA2 in heart and somite development. HMGA2 expression was first detected at HH stage 5 in the lateral plate mesoderm, a region synonymous with cells specified to the cardiac fate. HMGA2 was also strongly expressed in the presomitic segmental plate mesoderm and as somites developed from the segmental plate mesoderm, the expression of HMGA2 showed an increasingly more restricted domain corresponding to the level of maturation of the somite. Restriction of HMGA2 expression was first detected in the dorsal region of the epithelial somite, then the dorsomedial lip of the dermomyotome, and finally the migrating epaxial myotome cells. The novel intronless gene, C1-20C, predicts a protein of 148 amino acids containing a putative zinc finger binding domain and prenyl binding motif. Zinc binding assays showed that the zinc finger domain of C1-20C/MBP fusion protein bound over six times the quantity of zinc compared to MBP alone, although not in a 1:1 stoichiometric molar ratio. C1-20C/GFP fusion protein was shown to localise to as yet unidentified intracellular cytoplasmic vesicular compartments. These compartments did not colocalise with the endosome/lysosome pathway, aparently ruling out a role for C1-20C in protein trafficking, recycling or degradation. Expression of C1-20C in the chick embryo suggests a possible role in heart and notochord development and preliminary results using siRNA suggest that C1-20C is involved in normal heart looping.
Thesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Biomolecular and Biomedical Sciences
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Ragan, Sarah E. "Peering into the heart of galactic star formation : a detailed characterization of infrared-dark clouds /." [S.l. :] University of Michigan, 2009. http://adsabs.harvard.edu/abs/2009PhDT........12R.

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Blum, Kevin Matthew. "Mechanisms Guiding Neotissue Formation and Remodeling in Tissue Engineered Vascular Grafts." The Ohio State University, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=osu1614871166400724.

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Barnum, Martin J. "The eucharistic liturgy as a school of spiritual formation." Online full text .pdf document, available to Fuller patrons only, 2002. http://www.tren.com.

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Books on the topic "Heart formation"

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Muto, Susan Annette. Formation of the Christian heart. Pittsburgh, Pa: Epiphany Association, 2006.

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Formation of the human heart. New York, NY: Crossroad, 1985.

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Kaam, Adrian L. Van. Formation of the human heart. New York: Crossroad, 1986.

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Obsessed: Making Christ the desire of your heart. Nashville, TN: LifeWay Press, 2012.

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Tomanek, Robert J., and Raymond B. Runyan, eds. Formation of the Heart and Its Regulation. Boston, MA: Birkhäuser Boston, 2001. http://dx.doi.org/10.1007/978-1-4612-0207-3.

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Ashbrook, R. Thomas. Mansions of the heart: Exploring the seven stages of spiritual growth. San Francisco: Jossey-Bass, 2009.

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Heart and soul: A guide for spiritual formation in the local church. Nashville, TN: Upper Room, 1992.

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Path of the purified heart: The spiritual journey as transformation. Eugene, Or: Cascade Books, 2012.

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Living the sacred: Ten gateways to open your heart. London: Rider, 2000.

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Footprints of the heart: Putting feet on what you believe! York, South Carolina: Grace Peace Publishing, 2005.

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Book chapters on the topic "Heart formation"

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Kheradvar, Arash, and Gianni Pedrizzetti. "Vortex Formation in the Heart." In Vortex Formation in the Cardiovascular System, 45–79. London: Springer London, 2011. http://dx.doi.org/10.1007/978-1-4471-2288-3_3.

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Imachi, Kou, Yusuke Abe, Tsuneo Chinzei, Kunihiko Mabuchi, Kazunori Baba, Hiroyuki Matsuura, Akimasa Kouno, et al. "Calcification and Thrombus Formation on Polymer Surfaces of an Artificial Heart." In Heart Replacement, 110–17. Tokyo: Springer Japan, 1998. http://dx.doi.org/10.1007/978-4-431-65921-1_16.

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Markwald, Roger R., and Andy Wessels. "Overview of Heart Development." In Formation of the Heart and Its Regulation, 1–22. Boston, MA: Birkhäuser Boston, 2001. http://dx.doi.org/10.1007/978-1-4612-0207-3_1.

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Gregorio, Carol C., and Parker B. Antin. "Myofibrillogenesis in the Heart." In Formation of the Heart and Its Regulation, 23–43. Boston, MA: Birkhäuser Boston, 2001. http://dx.doi.org/10.1007/978-1-4612-0207-3_2.

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Nojiri, Chisato, Teruo Okano, Naoto Takemura, Kazuaki Senshu, Takayuki Kido, Hitoshi Koyanagi, Sung Wan Kim, and Tetsuzo Akutsu. "Improved Patency of HEMA/Styrene Block Copolymer-Coated Small Vessel Prosthesis Without Neointima Formation." In Heart Replacement, 53–60. Tokyo: Springer Japan, 1993. http://dx.doi.org/10.1007/978-4-431-67023-0_8.

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Simuț, Corneliu C. "‘The Book Has Warmed My Heart’: Spiritual Formation as Bible Reading in Charles Spurgeon." In Spiritual Formation, 77–82. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-97447-3_12.

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Simuț, Corneliu C. "‘The Book Has Warmed My Heart’: Spiritual Formation as Bible Reading in Charles Spurgeon." In Spiritual Formation, 77–82. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-97447-3_12.

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Srebnik, Herbert H. "Formation of Heart and Great Vessels." In Concepts in Anatomy, 61–68. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0857-1_10.

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Kirby, Margaret L. "Neural Crest and Heart Development." In Formation of the Heart and Its Regulation, 109–20. Boston, MA: Birkhäuser Boston, 2001. http://dx.doi.org/10.1007/978-1-4612-0207-3_6.

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Brink, Peter R., Ira S. Cohen, and Richard T. Mathias. "Integration of Stem Cells into the Cardiac Syncytium: Formation of Gap Junctions." In Regenerating the Heart, 301–20. Totowa, NJ: Humana Press, 2011. http://dx.doi.org/10.1007/978-1-61779-021-8_17.

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Conference papers on the topic "Heart formation"

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Tamura, Y., T. Miyasaka, and J. Shimizu. "Increased heart rate reduced crossbridge formation in beating rat whole heart." In 2012 IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI). IEEE, 2012. http://dx.doi.org/10.1109/bhi.2012.6211633.

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Seo, Jung Hee, Thura Abd, Richard T. George, and Rajat Mittal. "Video: Formation of Blood Clots in the Human Heart." In 68th Annual Meeting of the APS Division of Fluid Dynamics. American Physical Society, 2015. http://dx.doi.org/10.1103/aps.dfd.2015.gfm.v0023.

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McIntyre, Stephen D., Yoichiro Mori, and Elena G. Tolkacheva. "The Effect of Feedback on Alternans Formation in the Heart." In ASME 2012 5th Annual Dynamic Systems and Control Conference joint with the JSME 2012 11th Motion and Vibration Conference. ASME, 2012. http://dx.doi.org/10.1115/dscc2012-movic2012-8646.

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Bluestein, Danny, Wei Yin, Jolyon Jesty, Adam E. Saltman, Irvin B. Krukenkamp, Oscar Bernal, and Krishnamurthy Suresh. "Platelet Activation and Free Emboli Formation in Flow Past Mechanical Heart Valves." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-32288.

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Numerical studies, in vitro, and in vivo measurements were conducted, aimed at quantifying free emboli formation and procoagulant properties of platelets induced by flow past mechanical heart valves (MHV). Pulsatile turbulent flow simulation was conducted past a St. Jude medical MHV in the aortic position, to study the effects of valve implantation technique on the thromboembolic potential of the valve. A misaligned valve with subannualarly sutured pledgets produced accelerating jet flow through the valve orifices and a wider wake of shed vortices. Shear stress histories of platelets along turbulent trajectories exposed the platelets to elevated shear stresses around the leaflets, leading them to entrapment within the shed vortices. In vitro platelet studies were conducted past the MHV mounted in a recirculation flow loop and in a model of left ventricular assist device (LVAD), using an innovative platelet activity state (PAS) assay. The platelet activation significantly increased as a function of the recirculation time past the valve, and as compared to controls. Transcranial Doppler (TCD) measurements were conducted in the carotid artery of sheep with implanted MHV, showing marked increase in the number of HITS (High Intensity Transient Signals) signifying the passage of free emboli generated by the valve. The HITS were analyzed to distinguish between gaseous and thrombi emboli. Finally, platelet activity state measurements were conducted with sheep platelets, showing marked increase of platelet activation after valve implantation.
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Adib, Mohd Azrul Hisham Mohd, and Nur Hazreen Mohd Hasni. "Study the Heart Valve Elasticity and Optimal of Vortex Formation for Blood Circulation Measurement on the Left Ventricle Using the Heart Simulator (Heart-S) Apparatus." In ICBBE 2017: 2017 4th International Conference on Biomedical and Bioinformatics Engineering. New York, NY, USA: ACM, 2017. http://dx.doi.org/10.1145/3168776.3168786.

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Liu, Leening P., Nadav Shapira, Pooyan Sahbaee, Harold I. Litt, Marcus Y. Chen, and Peter B. Noël. "Dual-source photon-counting CT: consistency in spectral results at different acquisition modes and heart rates." In Seventh International Conference on Image Formation in X-Ray Computed Tomography (ICIFXCT 2022), edited by Joseph Webster Stayman. SPIE, 2022. http://dx.doi.org/10.1117/12.2646718.

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D'Antonio, Genevieve C., Bradley V. Weidner, Sarah A. Rowe, and Olga Pierrakos. "Evaluating the performance of prosthetic heart valves: transvalvular pressure drop vs. vortex ring formation number." In 2015 Systems and Information Engineering Design Symposium. IEEE, 2015. http://dx.doi.org/10.1109/sieds.2015.7117008.

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Stepan, Lenka, Daniel Levi, and Gregory Carman. "A Thin Film Nitinol Heart Valve." In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-60850.

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In order to create a less thrombogenic heart valve with improved longevity, a prosthetic heart valve was developed using thin film nitinol (NiTi). A “butterfly” thin film NiTi valve was constructed using a single, elliptical piece of thin film NiTi and a scaffold made from Teflon tubing and NiTi wire. Flow tests and pressure readings across the valve were performed in vitro in a pulsatile flow loop. Biocorrosion experiments were conducted on untreated and passivated thin film nitinol. To determine the material’s in vivo biocompatibility, thin film nitinol was implanted in a pig using a stent covered with thin film NiTi. Flow rates and pressure tracings across the valve were comparable to those through a commercially available 19 mm Perimount Edwards tissue valve. No signs of corrosion were present on samples of thin film nitinol after immersion in Hank’s solution for 1 month. Finally, organs and tissue samples explanted from the pig 17 days after thin film NiTi implantation appeared without disease, and the thin film nitinol itself was without thrombus formation or endothelialization. Although long term testing will be needed, thin film NiTi may be very well suited for use in artificial heart valves.
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Ramaswamy, Sharan, Danielle Gottlieb, John E. Mayer, and Michael S. Sacks. "Engineered Heart Valve Tissue Formation at the Organ Level: Effects of Flow Dynamics on Tissue Development." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-193216.

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Tissue engineered heart valve (TEHV) development protocols have yet to be optimized to an extent that can offer long-term function of value to patients, beyond contemporary clinical practices. One method of optimization may be possible through appropriate mechanical conditioning of the evolving engineered tissue before implantation. Engelmayr et al. [1] showed the synergistic benefits of combined flexural and fluid induced stresses on valvular-like tissue grown on rectangular scaffold strips. However, for clinical translation to be realized, it is important to determine if the nature of extracellular matrix production in such mechanistic studies also occurs at the macro-level, in the intact tri-leaflet valve geometry. Therefore, appropriate organ-level studies are required wherein the valvular tissues are subjected to the complex 3-dimensional flow/flexure/stretch regimes under highly controlled sub-, normal, and hyper-physiological flow levels. In this manner, biomechanical factors contributing to engineered tissue development can be coupled to tri-leaflet valve geometry requirements. In this study, one possible conditioning strategy on tri-leaflet TEHV structures is presented.
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Li, Yanmei, and Danny Bluestein. "The Effects of Implantation Techniques and Vortex Shedding on Free Emboli Formation in Mechanical Heart Valves." In ASME 1999 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1999. http://dx.doi.org/10.1115/imece1999-0390.

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Abstract A numerical analysis of pulsatile turbulent flow was conducted past a St. Jude Medical MHV in the aortic position, to study the effects of valve implantation technique on the thromboembolic potential of the valve. The simulation focussed on the assumption that by altering the flow fields past the valves, the valve orientation and the suturing technique employed have a favorable or undesirable effect on the thromboembolic potential of the valve. It was demonstrated that the combination of a valve that is not aligned with the axis of the blood flow and subannularly sutured pledgets, produced accelerating jet flow through the valve orifices and a wider wake of periodic shed vortices in the valve’s leaflets wake. The existence of the shed vortices was confirmed by Digital Particle Image Velocimetry (DPIV). measurements. Platelets paths that exposed the platelets to the highest shear levels led them to entrapment within the shed vortices, indicating that the risk of cardioembolism will be enhance.
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Reports on the topic "Heart formation"

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Burnham, Alan K. Estimating the Heat of Formation of Foodstuffs and Biomass. Office of Scientific and Technical Information (OSTI), November 2010. http://dx.doi.org/10.2172/1124948.

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Byrd, Edward F. Simple Computation of the Heat of Formation and Density from Theoretically Predicted Values. Fort Belvoir, VA: Defense Technical Information Center, September 2012. http://dx.doi.org/10.21236/ada570595.

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MORENO, JAMES B., KIM S. RAWLINSON, and SCOTT A. JONES. Methods and Energy Sources for Heating Subsurface Geological Formation, Task 1: Heat Delivery Systems. Office of Scientific and Technical Information (OSTI), January 2003. http://dx.doi.org/10.2172/809444.

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Wu, Yu-Shu. A comparison of analytical approaches for wellbore heat transmission in layered formations. Office of Scientific and Technical Information (OSTI), August 1988. http://dx.doi.org/10.2172/6918217.

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Thomas, Douglas, and Mellon Michael. Sublimation of terrestrial permafrost and the implications for ice-loss processes on Mars. Engineer Research and Development Center (U.S.), July 2021. http://dx.doi.org/10.21079/11681/41244.

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Sublimation of ice is rate-controlled by vapor transport away from its outer surface and may have generated landforms on Mars. In ice-cemented ground (permafrost), the lag of soil particles remaining after ice loss decreases subsequent sublimation. Varying soil-ice ratios lead to differential lag development. Here we report 52 years of sublimation measurements from a permafrost tunnel near Fairbanks, Alaska, and constrain models of sublimation, diffusion through porous soil, and lag formation. We derive the first long-term in situ effective diffusion coefficient of ice-free loess, a Mars analog soil, of 9.05 × 10⁻⁶ m² s⁻¹, ~5× larger than past theoretical studies. Exposed ice-wedge sublimation proceeds ~4× faster than predicted from analogy to heat loss by buoyant convection, a theory frequently employed in Mars studies. Our results can be used to map near-surface ice-content differences, identify surface processes controlling landform formation and morphology, and identify target landing sites for human exploration of Mars.
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Adams, David P., Deidre A. Hirschfeld, Ryan J. Hooper, and Michelle V. Manuel. Prediction and characterization of heat-affected zone formation due to neighboring nickel-aluminum multilayer foil reaction. Office of Scientific and Technical Information (OSTI), September 2015. http://dx.doi.org/10.2172/1222538.

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Desain, J. D., and T. J. Curtiss. The Predicted Heat of Formation of Several Si-Cl-O-H and Ti-Cl-O-H Species. Fort Belvoir, VA: Defense Technical Information Center, January 2006. http://dx.doi.org/10.21236/ada445087.

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Kingston, A. W., O. H. Ardakani, and R A Stern. Tracing the subsurface sulfur cycle using isotopic and elemental fingerprinting: from the micro to the macro scale. Natural Resources Canada/CMSS/Information Management, 2022. http://dx.doi.org/10.4095/329789.

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Hydrogen sulfide (H2S) is a toxic and corrosive gas that commonly occurs in deeply buried sedimentary systems. Understanding its distribution is paramount to creating safe and effective models of H2S occurrence aiding in the identification of high-risk areas. Characterizing subsurface sulfur sources and H2S formation pathways would enhance these models leading to more accurate predictions of potential high H2S regions. However, gaps remain in our understanding of the dominant formation processes and migration pathways of key ingredients for H2S production in the Lower Triassic Montney Formation of the Western Canada Sedimentary Basin (WCSB). Essential to this is assessing the reactants necessary for H2S production, potential pathways for fluid migration, diagenetic history, and changes in redox conditions through time. The Montney Formation has undergone several phases of diagenesis related to post-depositional alteration and multiple cycles of tectonic burial and uplift. Early chemical alteration includes dolomitization and, in some cases, microbial reduction of porewater sulfate to sulfide that occurred prior to significant burial (Davies et al., 1997; Vaisblat et al., 2021; Liseroudi et al., 2020, 2021). The most recent tectonic-related burial during the Laramide Orogeny resulted in burial depths in excess of 3-5 km (Ness, 2001; Ducros et al., 2017) leading to significant thermal and barometric alteration. Associated with this orogenic activity was the reactivation of underlying faults (O'Connell et al., 1990) and development of fractures especially near the deformation front. These fractures provide conduits for fluid migration into the Montney that combined with heat and pressure resulting in hydrocarbon generation, migration, and development of overpressure, notably in the western margin of the basin. In addition, high temperatures resulted in thermochemical sulfate reduction (TSR) leading to the formation of H2S and subsequently pyrite. We present an interpretation of the Montney subsurface sulfur cycle through the use of petrography, micro- and macro-scale geochemical analysis (isotopic and elemental) to illustrate the complexity of this system. This work relies heavily on previous studies within and outside our research group and incorporates new analytical techniques to expand the toolbox. We aim to guide future research directions and activities by addressing issues related to sampling and data quality issues, analytical approaches, and highlight knowledge gaps.
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N�ñez-Betelu, K., C. J. Collom, and L. V. Hills. Palynological data from the Kaskapau, Bad Heart, and Puskwaskau formations (Smoky Group: uppermost Turonian-upper Santonian), Smoky River, Alberta, Canada. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1999. http://dx.doi.org/10.4095/211013.

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Shomer, Ilan, Ruth E. Stark, Victor Gaba, and James D. Batteas. Understanding the hardening syndrome of potato (Solanum tuberosum L.) tuber tissue to eliminate textural defects in fresh and fresh-peeled/cut products. United States Department of Agriculture, November 2002. http://dx.doi.org/10.32747/2002.7587238.bard.

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The project sought to understand factors and mechanisms involved in the hardening of potato tubers. This syndrome inhibits heat softening due to intercellular adhesion (ICA) strengthening, compromising the marketing of industrially processed potatoes, particularly fresh peeled-cut or frozen tubers. However, ICA strengthening occurs under conditions which are inconsistent with the current ideas that relate it to Ca-pectate following pectin methyl esterase (PME) activity or to formation of rhamnogalacturonan (RG)-II-borate. First, it was necessary to induce strengthening of the middle lamellar complex (MLX) and the ICA as a stress response in some plant parenchyma. As normally this syndrome does not occur uniformly enough to study it, we devised an efficient model in which ICA-strengthening is induced consistently under simulated stress by short-chain, linear, mono-carboxylic acid molecules (OAM), at 65 oC [appendix 1 (Shomer&Kaaber, 2006)]. This rapid strengthening was insufficient for allowing the involved agents assembly to be identifiable; but it enabled us to develop an efficient in vitro system on potato tuber parenchyma slices at 25 ºC for 7 days, whereas unified stress was reliably simulated by OAMs in all the tissue cells. Such consistent ICA-strengthening in vitro was found to be induced according to the unique physicochemical features of each OAM as related to its lipophilicity (Ko/w), pKa, protonated proportion, and carbon chain length by the following parameters: OAM dissociation constant (Kdiss), adsorption affinity constant (KA), number of adsorbed OAMs required for ICA response (cooperativity factor) and the water-induced ICA (ICAwater). Notably, ICA-strengthening is accompanied by cell sap leakage, reflecting cell membrane rupture. In vitro, stress simulation by OAMs at pH<pKa facilitated the consistent assembly of ICAstrengthening agents, which we were able to characterize for the first time at the molecular level within purified insoluble cell wall of ICA-strengthened tissue. (a) With solid-state NMR, we established the chemical structure and covalent binding to cell walls of suberin-like agents associated exclusively with ICA strengthening [appendix 3 (Yu et al., 2006)]; (b) Using proteomics, 8 isoforms of cell wall-bound patatin (a soluble vacuolar 42-kDa protein) were identified exclusively in ICA-strengthened tissue; (c) With light/electron microscopy, ultrastructural characterization, histochemistry and immunolabeling, we co-localized patatin and pectin in the primary cell wall and prominently in the MLX; (d) determination of cell wall composition (pectin, neutral sugars, Ca-pectate) yielded similar results in both controls and ICA-strengthened tissue, implicating factors other than PME activity, Ca2+ or borate ions; (e) X-ray powder diffraction experiments revealed that the cellulose crystallinity in the cell wall is masked by pectin and neutral sugars (mainly galactan), whereas heat or enzymatic pectin degradation exposed the crystalline cellulose structure. Thus, we found that exclusively in ICA-strengthened tissue, heat-resistant pectin is evident in the presence of patatin and suberinlike agents, where the cellulose crystallinity was more hidden than in fresh control tissue. Conclusions: Stress response ICA-strengthening is simulated consistently by OAMs at pH< pKa, although PME and formation of Ca-pectate and RG-II-borate are inhibited. By contrast, at pH>pKa and particularly at pH 7, ICA-strengthening is mostly inhibited, although PME activity and formation of Ca-pectate or RG-II-borate are known to be facilitated. We found that upon stress, vacuolar patatin is released with cell sap leakage, allowing the patatin to associate with the pectin in both the primary cell wall and the MLX. The stress response also includes formation of covalently bound suberin-like polyesters within the insoluble cell wall. The experiments validated the hypotheses, thus led to a novel picture of the structural and molecular alterations responsible for the textural behavior of potato tuber. These findings represent a breakthrough towards understanding of the hardening syndrome, laying the groundwork for potato-handling strategies that assure textural quality of industrially processed particularly in fresh peeled cut tubers, ready-to-prepare and frozen preserved products.
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