Academic literature on the topic 'Heart diseases in Singapore'

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Journal articles on the topic "Heart diseases in Singapore"

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Tan, Rayner Kay Jin, Alvin Kuo Jing Teo, Nashwinder Kaur, Jack Harrison-Quintana, Mark I-Cheng Chen, and Chen Seong Wong. "Cost and anonymity as factors for the effective implementation of pre-exposure prophylaxis: an observational study among gay, bisexual and other men who have sex with men in Singapore." Sexual Health 15, no. 6 (2018): 533. http://dx.doi.org/10.1071/sh18059.

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Background HIV pre-exposure prophylaxis (PrEP) is currently offered by several public and private clinics at unsubsidised prices in Singapore, but to date, no information is available on the effect of these services. This study sought to assess the knowledge and uptake of, and willingness to use PrEP among gay, bisexual and other men who have sex with men (GBMSM) in Singapore. Methods: Recruitment was conducted through Grindr®, a geosocial networking application for GBMSM. Results were quantitatively analysed through descriptive statistics and multivariate Poisson regression models, while open-ended responses were qualitatively coded and categorised. Results: Of the 1339 participants who responded, 1098 participants who indicated their knowledge and use of PrEP were included in the analytic sample. Overall, 15.0% (n=154) had taken PrEP, 66.2% (n=678) had heard of but not taken PrEP, while 18.8% (n=193) had never heard of PrEP. Of those who had ever taken PrEP, 59.6% (n=90) had obtained PrEP from overseas or other unofficial sources. Of those who had heard of but never taken PrEP, 73.3% (n=486) reported that they would consider taking PrEP. Those who had taken PrEP were older and had higher educational attainment. Conclusions: The gap between the willingness to use PrEP and its uptake may be attributed to the cost of PrEP and issues of anonymity at healthcare settings in Singapore. National financing schemes are needed to expand access to PrEP if it is to make a meaningful effect to the Singapore HIV/AIDS response.
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Song, Jae-Hoon, Keiichi Hiramatsu, Ji Yoeun Suh, Kwan Soo Ko, Teruyo Ito, Maria Kapi, Sungmin Kiem, et al. "Emergence in Asian Countries of Staphylococcus aureus with Reduced Susceptibility to Vancomycin." Antimicrobial Agents and Chemotherapy 48, no. 12 (December 2004): 4926–28. http://dx.doi.org/10.1128/aac.48.12.4926-4928.2004.

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ABSTRACT To investigate the prevalence of Staphylococcus aureus with reduced susceptibility to vancomycin among methicillin-resistant S. aureus (MRSA) strains in Asian countries, a total of 1,357 clinical isolates of MRSA collected from 12 Asian countries were screened by using brain heart infusion agar plates containing 4 mg of vancomycin per liter. The presence of strains that were heterointermediately resistant to vancomycin (hVISA) was confirmed by population analysis. Of 347 (25.6%) MRSA isolates that grew on the screening agar plates, 58 isolates (4.3%) were hVISA. hVISA strains were found in India, South Korea, Japan, the Philippines, Singapore, Thailand, and Vietnam. However, neither vancomycin-intermediate S. aureus nor vancomycin-resistant S. aureus isolates were found among MRSA isolates from Asian countries in this survey.
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Fatima, Samreen, Sayed Saad Ali, Syeda Sadia Zia, Ehtesham Hussain, Tayyab Raza Fraz, and Mehwish Shafi Khan. "Forecasting Carbon Dioxide Emission of Asian Countries Using ARIMA and Simple Exponential Smoothing Models." International Journal of Economic and Environmental Geology 10, no. 1 (May 24, 2019): 64–69. http://dx.doi.org/10.46660/ijeeg.vol10.iss1.2019.219.

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Industrial revolution has increased the level of pollution due to emission of carbon dioxide in the past fewdecades. Resulting changes in the world’s climate are seen in the form of an increase in temperature which causes heatwaves, diseases related to skin, cardiovascular and other respiratory illnesses in humans. According to a past study,overall contribution of continent Asia is 49% - 50% in the production of carbon dioxide. Therefore, data of carbondioxide emission, heat and electricity, manufacturing industries, residential and commercial buildings, transport andother sources of Asian countries namely: Japan, Bangladesh, China, Pakistan, India, Sri Lanka, Iran, Singapore, andNepal from 1971 to 2014 have been taken for the present study. Empirical analysis shows that heat and electricity arethe main cause to increase carbon dioxide emission in Pakistan, Bangladesh, India, Iran and Sri Lanka. Whereas thisemission is increased in China due to residential and commercial buildings and transport variables. On the other hand,for Nepal and Singapore, these variables do not play any significant role in CO2 emission. Simple exponentialsmoothing (SES) and ARIMA models are used to forecast CO2 emissions. Furthermore, simple exponential smoothingis found appropriate for Pakistan and Sri Lanka based on the minimum FMAE. Whereas, for Japan, China, India, Iranand Singapore, ARIMA model is found suitable as it has minimum FMAE value. In Nepal and Bangladesh, bothmodels have significant differences, so any one of them can be used for forecasting.
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Fatima, Samreen, Sayed Saad Ali, Syeda Sadia Zia, Ehtesham Hussain, Tayyab Raza Fraz, and Mehwish Shafi Khan. "Forecasting Carbon Dioxide Emission of Asian Countries Using ARIMA and Simple Exponential Smoothing Models." International Journal of Economic and Environmental Geology 10, no. 1 (May 24, 2019): 64–69. http://dx.doi.org/10.46660/ojs.v10i1.219.

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Industrial revolution has increased the level of pollution due to emission of carbon dioxide in the past fewdecades. Resulting changes in the world’s climate are seen in the form of an increase in temperature which causes heatwaves, diseases related to skin, cardiovascular and other respiratory illnesses in humans. According to a past study,overall contribution of continent Asia is 49% - 50% in the production of carbon dioxide. Therefore, data of carbondioxide emission, heat and electricity, manufacturing industries, residential and commercial buildings, transport andother sources of Asian countries namely: Japan, Bangladesh, China, Pakistan, India, Sri Lanka, Iran, Singapore, andNepal from 1971 to 2014 have been taken for the present study. Empirical analysis shows that heat and electricity arethe main cause to increase carbon dioxide emission in Pakistan, Bangladesh, India, Iran and Sri Lanka. Whereas thisemission is increased in China due to residential and commercial buildings and transport variables. On the other hand,for Nepal and Singapore, these variables do not play any significant role in CO2 emission. Simple exponentialsmoothing (SES) and ARIMA models are used to forecast CO2 emissions. Furthermore, simple exponential smoothingis found appropriate for Pakistan and Sri Lanka based on the minimum FMAE. Whereas, for Japan, China, India, Iranand Singapore, ARIMA model is found suitable as it has minimum FMAE value. In Nepal and Bangladesh, bothmodels have significant differences, so any one of them can be used for forecasting.
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Atwood, Stephen J. "It is a Small World: Global Medical Education for the Twenty-first Century." Einstein Journal of Biology and Medicine 21, no. 1 (March 2, 2016): 38. http://dx.doi.org/10.23861/ejbm200421450.

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Last year’s epidemic of the Severe Acute Respiratory Syndrome (SARS) virus in Asia and the present world-wide concern about the spread of the H5N1 avian flu virus has brought international health concerns to the front pages of national and international newspapers, newsmagazines, and health journals around the world. Add to this the global Human Immunodeficiency Virus (HIV) epidemic, the global resurgence of tuberculosis (TB), and the disturbing increases in antibiotic-resistant bacteria, and it becomes difficult to imagine the compartmentalized world of even 30 years ago when diseases of different continents stayed in their place. Today, more than one million people cross international borders each day (not including refugees and displaced persons). Air transport guarantees a rapid transit of both person and pathogen well within the incubation period of many diseases. Body-heat detectors used recently at immigration points (e.g., Singapore and Hanoi) to detect febrile passengers are symbolic of the coarse screening attempts being used to control the movement of contagious diseases.
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Jiang, Ying, Shefaly Shorey, Hoang D. Nguyen, Vivien Xi Wu, Choy Yee Lee, Lee Fung Yang, Karen Wei Ling Koh, and Wenru Wang. "The development and pilot study of a nurse-led HOMe-based HEart failure self-Management Programme (the HOM-HEMP) for patients with chronic heart failure, following Medical Research Council guidelines." European Journal of Cardiovascular Nursing 19, no. 3 (September 5, 2019): 212–22. http://dx.doi.org/10.1177/1474515119872853.

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Background: Chronic heart failure (CHF) is one of the most common causes of hospital admissions and readmissions. Managing CHF requires a comprehensive treatment plan that consists of medication treatment and behavioural change. However, patients often feel unprepared for their self-management role in the community, especially during the period of transition after discharge from hospital. Therefore, an effective intervention to promote CHF self-management is needed. Aims: This paper describes the development and pilot testing of a multicomponent nursing intervention (i.e. the HOM-HEMP) for a randomised controlled trial to assess its effectiveness in improving self-care behaviour among CHF patients in Singapore. A description of the study intervention is also delineated in detail. Methods: The HOM-HEMP was developed based on the UK Medical Research Council framework for developing and evaluating complex interventions. After the development of the study intervention, a single group pre- and post-repeated measure pilot test was conducted to evaluate the study intervention package for its acceptability and the feasibility of the data collection procedure. Ten participants were recruited through consecutive sampling. All of the participants received the full intervention package with the supplementary mobile application. The data were collected at baseline and immediately after the study intervention (i.e. 6 weeks from baseline). The outcome measures included the Self-Care Heart Failure Index, Cardiac Self-Efficacy Scale, Minnesota Living with Heart Failure Questionnaire, Hospital Anxiety and Depression Scale and Short Form of the Social Support Questionnaire. Results: The results from the pilot testing showed that the programme was feasible and potentially effective in improving patient’s self-care management, psychological outcomes and health-related quality of life. Conclusion: A self-management psychosocial education approach is the preferred choice for many patients with chronic diseases. The effectiveness of the HOM-HEMP will next be tested in a full scale randomised control trial.
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Goh, K. T., S. H. Teo, L. Tay, and E. H. A. Monteiro. "Epidemiology and control of an outbreak of typhoid in a psychiatric institution." Epidemiology and Infection 108, no. 2 (April 1992): 221–30. http://dx.doi.org/10.1017/s0950268800049700.

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SUMMARYAn outbreak of typhoid caused by Salmonella typhi of the same Vi-phage type (D1) and of the same antibiogram was reported in a large psychiatric institution in Singapore. A total of 95 (4·8%) of the 1965 inmates were infected, 47 with symptoms and 48 asymptomatic. Transmission was through close person-to-person contact and not through contaminated food or water. The source of infection could not be established. The outbreak was brought under control by maintaining a high standard of environmental sanitation, active search for fever and diarrhoeal cases, identification of asymptomatic cases by rectal swabbing, and isolation of those found to be infected. Mass immunization with two doses of heat-phenol inactivated typhoid vaccine was also carried out concurrently. The vaccine was found to have an efficacy of 65·8% in preventing clinical illness.
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Ho, Andrew FW, Kai Yi Lee, Xinyi Lin, Ying Hao, Nur Shahidah, Yih Yng Ng, Benjamin SH Leong, et al. "Nation-Wide Observational Study of Cardiac Arrests Occurring in Nursing Homes and Nursing Facilities in Singapore." Annals of the Academy of Medicine, Singapore 49, no. 5 (May 31, 2020): 285–93. http://dx.doi.org/10.47102/annals-acadmed.sg.2019244.

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Introduction: Nursing home (NH) residents with out-of-hospital cardiac arrests (OHCA) have unique resuscitation priorities. This study aimed to describe OHCA characteristics in NH residents and identify independent predictors of survival. Materials and Methods: OHCA cases between 2010–16 in the Pan-Asian Resuscitation Outcomes Study were retrospectively analysed. Patients aged <18 years old and non-emergency cases were excluded. Primary outcome was survival at discharge or 30 days. Good neurological outcome was defined as a cerebral performance score between 1–2. Results: A total of 12,112 cases were included. Of these, 449 (3.7%) were NH residents who were older (median age 79 years, range 69–87 years) and more likely to have a history of stroke, heart and respiratory diseases. Fewer NH OHCA had presumed cardiac aetiology (62% vs 70%, P <0.01) and initial shockable rhythm (8.9% vs 18%, P <0.01), but had higher incidence of bystander cardiopulmonary resuscitation (74% vs 43%, P <0.01) and defibrillator use (8.5% vs 2.8%, P <0.01). Non-NH (2.8%) residents had better neurological outcomes than NH (0.9%) residents (P <0.05). Factors associated with survival for cardiac aetiology included age <65 years old, witnessed arrest, bystander defibrillator use and initial shockable rhythm; for non-cardiac aetiology, these included witnessed arrest (adjusted odds ratio [AOR] 3.8, P <0.001) and initial shockable rhythm (AOR 5.7, P <0.001). Conclusion: Neurological outcomes were poorer in NH survivors of OHCA. These findings should inform health policies on termination of resuscitation, advance care directives and do-not-resuscitate orders in this population. Ann Acad Med Singapore 2020;49:285–93 Key words: Advance care directives, Do-not-resuscitate orders, Geriatrics, Out-of- hospital, Palliative care
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Heil, D. P., R. U. Newton, and D. D. A. Salle. "Characterizing the Metabolic Intensity and Cardiovascular Demands of Walking Football in Southeast Asian Women." International Journal of Physical Education, Fitness and Sports 7, no. 3 (September 30, 2018): 12–23. http://dx.doi.org/10.26524/ijpefs1832.

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Given that the recent rise in obesity rates throughout Southeast Asia is disproportionately driven by women, part of the regional solution may be to encourage more habitual physical activity within this population. Taking advantage of the regional popularity of walking football, this study sought to characterize thecardiovascular demands and metabolic intensity of Southeast Asian women competing in walking football matches to determine the sports’ suitability for promoting physical health. It was hypothesized that both cardiovascular and metabolic intensity measures (≥65% HR% and ≥3.0 METs, respectively) would meet or exceed established thresholds for improving fitness and health. Methods: Women’s teams from Singapore (Mean±SD: 42±11 yrs age; 29.2±7.0 kg/m2 BMI; n=14) and Malaysia (40±10 yrs age; 32.9±5.7 kg/m2 BMI; n=8) competed in two successive matches within a single day during which measures of heart rate (HR) and GPS (from portable handheld device) were recorded for each player, while relative HR was computed as a percent of each player’s age-predicted maximal HR (HR%, %). The GPS data were later converted to walking distance and metabolic intensity (i.e., metabolic equivalents, or METs). One-sample t-tests at the 0.05 alpha level were used to compare variables to their respective thresholds. Results: Both Malaysian and Singaporean teams had mean relative HRs (91-95% of HRMAX [P=0.008] versus 77-80% of HRMAX [P<0.001], respectively) that exceeded the 65% threshold for improving cardiovascular fitness. Both teams also maintained an average metabolic intensity that was statistically similar to the 3.0 MET threshold that decreases one risk for non-communicable diseases (3.2±0.9 METs [P=0.0510] versus (3.3±1.0 METs [P=0.288], respectively), and both teams walked an average of 2.2-2.4 kms/match. Conclusions: These results support the idea that competitive walking football is of sufficient intensity to promote positive changes in both cardiovascular and metabolic fitness in this population of Southeast Asian women.
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Phang, Lim Yeong, and Tan Yong Seng. "Management of Cardiac Myxomas." Asian Cardiovascular and Thoracic Annals 5, no. 3 (September 1997): 158–61. http://dx.doi.org/10.1177/021849239700500308.

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Cardiac myxomas are benign primary tumors of the heart that require prompt surgical intervention because of the possibility of developing syncope and hemodynamic or embolic complications. From 1 January 1981 to 31 December 1996, 20 patients (11 male and 9 female) underwent surgery for cardiac myxoma at Singapore General Hospital. Nineteen patients had a left atrial myxoma and 1 had a right atrial myxoma. Five patients had concomitant coronary artery disease including one with severe mitral regurgitation. Nine patients presented with progressive dyspnea, 5 with systemic embolus, 2 with syncope, 3 with congestive cardiac failure, and 1 with right ventricular failure. In 6 patients the diagnosis was established by cardiac catheterization and 14 patients were diagnosed by two-dimensional echocardiography. Cardiopulmonary bypass with mild to moderate systemic hypothermia was used for excision of the myxoma in all cases. Five patients had concomitant coronary artery bypass grafting and 2 had concomitant mitral valve replacement. There was no hospital mortality among patients who had only excision of the myxoma, including a patient who had a recurrence of her left atrial myxoma 5 years after the initial excision. There were 2 deaths in patients with coexisting cardiac and other diseases. Surgical excision is recommended for all cases of cardiac myxoma. There is little risk associated with this procedure. All patients should be followed up regularly with echocardiographic assessment as there is a small risk of recurrence.
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Dissertations / Theses on the topic "Heart diseases in Singapore"

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Hughes, Kenneth. "The epidemiology of cardiovascular diseases in the ethnic groups in Singapore." Thesis, University of Oxford, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.235906.

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Savatteri, Giuseppe. "Enviromental factors influencing heart diseases." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2020.

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È importante individuare strategie e meccanismi per sfruttare le opportunità offerte dalla digitalizzazione in ambito sanitario delle attività e dalla gestione dei Big Data per migliorare efficienza, monitoraggio, prevenzione e cura delle patologie. possibilità di applicazione della medicina di precisione, refertazione in anatomia patologica e automazione della raccolta dati. Il lavoro di tesi è incentrato sulle problematiche legate alle malattie cardio-cerebrovascolari e la loro correlazione con il territorio con cui i soggetti interagiscono. È stato realizzato un nuovo sistema di monitoraggio del territorio che possa individuare possibili legami tra la composizione del territorio, in termini di opere pubbliche e private, e lo stato di salute delle persone. Un apposito insieme di dati viene fornito al modello di modello di machine learning, basato sulle reti neurali e provvederà ad operare nell'estrazione di possibili correlazioni tra la tipologia di edifici e la percentuale di soggetti a rischio cardiovascolare.
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Swerdan, Stephanie. "Modeling Heart Diseases in Drosophila." Thesis, The University of Arizona, 2012. http://hdl.handle.net/10150/244831.

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Fragile X mental retardation protein (FMRP) plays an important role in heart development and disease. Here we set out to create a Drosophila model of heart disease that will complement the existing mouse model based on Fragile X protein deficiency. Proteins within the Fragile X family are RNA binding proteins that control the translation of specific RNAs. Previous studies have shown that loss of Fragile X mental retardation protein, autosomal homolog 1 (FXR1) leads to heart phenotypes in the mouse. The Drosophila model will allow us to perform rapid genetic rescue experiments to identify specific targets of FMR1, the only type of FMR expressed in the fly, that are responsible for creating the structural and functional defects when FMR1 is repressed. To create a model of heart disease in the fly, we knocked down FMR1 and examined its effects by measuring the heart rate in early pupae. We discovered that the total loss of function for FMR1 leads a decreased heart rate. Interestingly, heterozygous loss of function (LOF) mutants exhibited a significant decrease in heart rate that could be partially rescued by inserting hFXR1, a human homolog of FMRP.
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Alsalamah, Mashail. "Heart diseases diagnosis using artificial neural networks." Thesis, Coventry University, 2017. http://curve.coventry.ac.uk/open/items/a9564d2b-df62-4573-8888-cabdbbdcd4e0/1.

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Information technology has virtually altered every aspect of human life in the present era. The application of informatics in the health sector is rapidly gaining prominence and the benefits of this innovative paradigm are being realized across the globe. This evolution produced large number of patients’ data that can be employed by computer technologies and machine learning techniques, and turned into useful information and knowledge. This data can be used to develop expert systems to help in diagnosing some life-threating diseases such as heart diseases, with less cost, processing time and improved diagnosis accuracy. Even though, modern medicine is generating huge amount of data every day, little has been done to use this available data to solve challenges faced in the successful diagnosis of heart diseases. Highlighting the need for more research into the usage of robust data mining techniques to help health care professionals in the diagnosis of heart diseases and other debilitating disease conditions. Based on the foregoing, this thesis aims to develop a health informatics system for the classification of heart diseases using data mining techniques focusing on Radial Basis functions and emerging Neural Networks approach. The presented research involves three development stages; firstly, the development of a preliminary classification system for Coronary Artery Disease (CAD) using Radial Basis Function (RBF) neural networks. The research then deploys the deep learning approach to detect three different types of heart diseases i.e. Sleep Apnea, Arrhythmias and CAD by designing two novel classification systems; the first adopt a novel deep neural network method (with Rectified Linear unit activation) design as the second approach in this thesis and the other implements a novel multilayer kernel machine to mimic the behaviour of deep learning as the third approach. Additionally, this thesis uses a dataset obtained from patients, and employs normalization and feature extraction means to explore it in a unique way that facilitates its usage for training and validating different classification methods. This unique dataset is useful to researchers and practitioners working in heart disease treatment and diagnosis. The findings from the study reveal that the proposed models have high classification performance that is comparable, or perhaps exceed in some cases, the existing automated and manual methods of heart disease diagnosis. Besides, the proposed deep-learning models provide better performance when applied on large data sets (e.g., in the case of Sleep Apnea), with reasonable performance with smaller data sets. The proposed system for clinical diagnoses of heart diseases, contributes to the accurate detection of such disease, and could serve as an important tool in the area of clinic support system. The outcome of this study in form of implementation tool can be used by cardiologists to help them make more consistent diagnosis of heart diseases.
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Hopmeyer, Joanne. "Effect of physiologic parameters on the quantification of mitral regurgitation using the flow convergence method." Diss., Georgia Institute of Technology, 1996. http://hdl.handle.net/1853/10969.

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Phoku, Nkosinathi Terrence. "Cardiovascular risk factors among 15-20 years old rural subjects residing in Dikgale Demographic Surveillance Site (DDSS), Limpopo Province." Thesis, University of Limpopo (Turfloop Campus), 2013. http://hdl.handle.net/10386/1048.

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Thesis (M.Sc. (Chemical Pathology) --University of Limpopo, 2013
Cardiovascular diseases (CVDs) are among one of the well documented conditions and pose a significant health burden in the world as they areconsidered to be of adult onset. However, recent studies have shown that in developed countries CVD risk factors are becoming prevalent in young people which isof great concern. Therefore, the aim of this study was to determine if CVD risk factors are present in young subjects aged 15-20 years of age residing in a rural area of a developing country. Methods: Subjects aged between 15-20 years who participated in the “Gene - Environment interaction project” were included in this sub-study. Total cholesterol, triglycerides, HDL-cholesterol, LDLcholesterol, insulin, glucose, creatinine, Lp(a), apoB, apoA-1 and hs-CRPwere determined. Blood pressure, physical activity (number of steps/day), weight, height, waist circumference and hip circumference were obtained from the database. Subjects with CRP levels above 10mg/L and creatinine levels above 130 mmol/L were excluded. Results: The present study showed an overall high prevalence of some CVD risk factors. There was high prevalence of insulin resistance (23.0% in females and 34.7% in males), and high hs-CRP (18.4% in females, 12.9% in males). The prevalence of low HDL-C levels was high (55.2% in females and 16.8 % in males), however, the prevalence of abnormal levels of other lipids such as total cholesterol/HDL-cholesterol ratio was low in both males and females. The prevalence of an increased apoB/apoA ratio was significantly higher in females 26.4% compared to males 7.9%. The prevalence of overweight (12.6%) and obesity (9.2%) was higher in females than in males (overweight 1%, obesity 0 %). The prevalence of hypertension was comparable between the two genders (5.7% in females and 10.9 % in males). Conclusion: The results showed a relatively high prevalence of non-traditional risk factors for cardiovascular diseases in adolescents residing in a rural area, Limpopo Province, while the prevalence of traditional risk factors such as total cholesterol and triglycerides was low.
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Burleson, Armelle Cagniot. "Analysis of turbulent jets for the determination of heart valve leakage." Diss., Georgia Institute of Technology, 1993. http://hdl.handle.net/1853/11307.

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李詠鸞 and Wing-luen Lee. "Multidisciplinary cardiac program for patients with heart failure." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43251328.

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Yao, Guiqing. "The economic evaluations of interventions for heart diseases." Thesis, University of Birmingham, 2010. http://etheses.bham.ac.uk//id/eprint/1058/.

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The primary aim of the thesis was to report new cost-effectiveness evidence in the clinical area of heart disease. Following a review of published empirical work, this was achieved by undertaking three new cost-effectiveness studies: one in nurse-led secondary prevention clinics for coronary heart disease in primary care, one on cardiac resynchronisation therapy with or without an implantable cardioverter defibrillator in chronic heart failure, and the final one on a new drug therapy, nebivolol, compared with standard treatment in elderly patients with heart failure. The second aim of the thesis concerned the application of modelling methodology, with the intent being the provision of general recommendations in using Markov modelling approaches in economic evaluation conducted in the heart disease area. The focus was on extrapolation of cost-effectiveness of an intervention beyond a trial both in terms of the time horizon of the analysis and in relation to the population involved. Fundamental issues in parametric distribution functions and Markov modelling approaches have been revisited, with detailed consideration of which parametric distribution functions should be employed when extrapolating beyond a trial and how they could be adopted into model-based analyses. The need for further methodology investigations in this area is discussed in conclusion.
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Lefebvre, Xavier. "Systolic anterior motion of the mitral valve in obstructive hypertrophic cardiomyopathy : an in-vitro study." Diss., Georgia Institute of Technology, 1992. http://hdl.handle.net/1853/11712.

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Books on the topic "Heart diseases in Singapore"

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Heart disease. 2nd ed. New York: Macmillan Pub. Co., 1987.

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Rickert-Sperling, Silke, Robert G. Kelly, and David J. Driscoll, eds. Congenital Heart Diseases: The Broken Heart. Vienna: Springer Vienna, 2016. http://dx.doi.org/10.1007/978-3-7091-1883-2.

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Khan, M. I. Gabriel. Encyclopedia of heart diseases. Oxford: Academic, 2004.

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Khan, M. I. Gabriel. Encyclopedia of heart diseases. 2nd ed. New York, NY: Springer, 2011.

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Khan, M. I. Gabriel. Encyclopedia of heart diseases. Burlington, MA: Elsevier Academic, 2006.

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Hollenberg, Norman K., ed. Atlas of Heart Diseases. London: Current Medicine Group, 2001. http://dx.doi.org/10.1007/978-1-4684-6909-7.

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Abdulla, Ra-id, ed. Heart Diseases in Children. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-1-4419-7994-0.

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Silverstein, Alvin. Heart disease. Minneapolis, Minn: Twenty-First Century Books, 2006.

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Michael, Reingold, ed. Heart disease. New York: J. Messner, 1986.

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Heart disease. Oxford: Oxford University Press, 2010.

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Book chapters on the topic "Heart diseases in Singapore"

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Colombo, Joseph, Rohit Arora, Nicholas L. DePace, and Aaron I. Vinik. "Heart Diseases." In Clinical Autonomic Dysfunction, 205–26. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-07371-2_19.

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Nagaratnam, Nages, Kujan Nagaratnam, and Gary Cheuk. "Heart Failure." In Geriatric Diseases, 3–16. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-33434-9_1.

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Nagaratnam, Nages, Kujan Nagaratnam, and Gary Cheuk. "Heart Failure." In Geriatric Diseases, 1–13. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-32700-6_1-1.

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Fry, John. "Ischaemic Heart Disease." In Common Diseases, 151–60. Dordrecht: Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-009-4924-9_17.

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Chessa, Massimo, and Fatma Aboalsoud Taha. "Congenital Heart Diseases." In Handbook of Psychocardiology, 407–37. Singapore: Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-287-206-7_22.

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Rustamova, Yasmin, and Massimo Lombardi. "Valvular Heart Diseases." In Cardiac Magnetic Resonance Atlas, 93–122. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-41830-4_4.

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Rustamova, Yasmin, and Massimo Lombardi. "Congenital Heart Diseases." In Cardiac Magnetic Resonance Atlas, 171–98. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-41830-4_7.

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Bogaert, J., and A. M. Taylor. "Heart Muscle Diseases." In Clinical Cardiac MRI, 275–353. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/174_2011_358.

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Khan, M. Gabriel. "Endocrine Heart Diseases." In Contemporary Cardiology, 571–91. Totowa, NJ: Humana Press, 2014. http://dx.doi.org/10.1007/978-1-61779-962-4_18.

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Yin, Wei-Hsian, and Ming-Chon Hsiung. "Congenital Heart Diseases." In Atlas of Perioperative 3D Transesophageal Echocardiography, 121–46. Singapore: Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-10-0587-9_7.

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Conference papers on the topic "Heart diseases in Singapore"

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Mesihović-Dinarević, Senka, Mirza Halimić, and Almira Kadić. "ACQUIRED AND GENETICALLY PREDISPOSED HEART DISEASE IN CHILDREN." In Acquired Heart Diseases. Academy of Sciences and Arts of Bosnia and Herzegovina, 2015. http://dx.doi.org/10.5644/pi2015-158-01.

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Omerčahić-Dizdarević, Aida, Velma Selmanović, and Adisa Čengić. "RHEUMATIC FEVER: A DISEASE THAT SHOULD NOT YET BE FORGOTTEN." In Acquired Heart Diseases. Academy of Sciences and Arts of Bosnia and Herzegovina, 2015. http://dx.doi.org/10.5644/pi2015-158-02.

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Begić, Fatima. "ACQUIRED VALVULAR HEART DISEASE IN CHILDREN: OUR EXAMPLES." In Acquired Heart Diseases. Academy of Sciences and Arts of Bosnia and Herzegovina, 2015. http://dx.doi.org/10.5644/pi2015-158-03.

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Cerić, Šejla, and Elma Kučukalić-Selimović. "THE IMPORTANCE OF PHARMACOLOGICAL STRESS IN MYOCARDIAL PERFUSION SCINTIGRAPHY." In Acquired Heart Diseases. Academy of Sciences and Arts of Bosnia and Herzegovina, 2015. http://dx.doi.org/10.5644/pi2015-158-04.

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Kušljugić, Zumreta, and Katarina Kovačević. "BRUCELLA ENDOCARDITIS: A CASE STUDY." In Acquired Heart Diseases. Academy of Sciences and Arts of Bosnia and Herzegovina, 2015. http://dx.doi.org/10.5644/pi2015-158-05.

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Kulić, Mehmed, Ibrahim Terzić, Mirza Dilić, Elnur Tahirović, and Muhamed Spužić. "PRIMARY PERCUTANEOUS CORONARY INTERVENTIONS NETWORK IN BOSNIA AND HERZEGOVINA." In Acquired Heart Diseases. Academy of Sciences and Arts of Bosnia and Herzegovina, 2015. http://dx.doi.org/10.5644/pi2015-158-06.

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Haxhibeqiri-Karabdić, Ilirijana, Emir Kabil, and Haris Vranić. "ISCHAEMIC HEART DISEASE – SURGICAL TREATMENT AND POST-OPERATIVE COMPLICATIONS." In Acquired Heart Diseases. Academy of Sciences and Arts of Bosnia and Herzegovina, 2015. http://dx.doi.org/10.5644/pi2015-158-07.

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Pandur, Sanko. "REVIEW UP-TO-DATE CORONARY ARTERY BYPASS GRAFT SURGERY." In Acquired Heart Diseases. Academy of Sciences and Arts of Bosnia and Herzegovina, 2015. http://dx.doi.org/10.5644/pi2015-158-08.

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Patel, Ankeeta R., and Maulin M. Joshi. "Heart diseases diagnosis using neural network." In 2013 Fourth International Conference on Computing, Communications and Networking Technologies (ICCCNT). IEEE, 2013. http://dx.doi.org/10.1109/icccnt.2013.6726740.

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Krželj, Vjekoslav, and Ivana Čulo Čagalj. "INHERITED METABOLIC DISORDERS AND HEART DISEASES." In Symposium with International Participation HEART AND … Akademija nauka i umjetnosti Bosne i Hercegovine, 2019. http://dx.doi.org/10.5644/pi2019.181.02.

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Abstract:
Inherited metabolic disorders can cause heart diseases, cardiomyopathy in particular, as well as cardiac arrhythmias, valvular and coronary diseases. More than 40 different inherited metabolic disorders can provoke cardiomyopathy, including lysosomal storage disorders, fatty acid oxidation defects, organic acidemias, amino acidopathies, glycogen storage diseases, congenital disorders of glycosylation as well as peroxisomal and mitochondrial disorders. If identified and diagnosed on time, some of congenital metabolic diseases could be successfully treated. It is important to assume them in cases when heart diseases are etiologically undefined. Rapid technological development has made it easier to establish the diagnosis of these diseases. This article will focus on common inherited metabolic disorders that cause heart diseases, as well as on diseases that might be possible to treat.
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Reports on the topic "Heart diseases in Singapore"

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Aleksandrov, A. V., L. N. Shilova, I. Yu Alekhina, N. V. Aleksandrova, N. V. Nikitina, and E. V. Benedickaya. COMBINED USE OF IMMUNOLOGICAL AND ULTRASOUND METHODS OF ESTIMATION OF VALVE HEART STATUS IN PATIENTS WITH INFLAMMATORY RHEUMATIC DISEASES. Планета, 2018. http://dx.doi.org/10.18411/978-5-907109-24-7-2018-xxxv-14-18.

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Treadwell, Jonathan R., James T. Reston, Benjamin Rouse, Joann Fontanarosa, Neha Patel, and Nikhil K. Mull. Automated-Entry Patient-Generated Health Data for Chronic Conditions: The Evidence on Health Outcomes. Agency for Healthcare Research and Quality (AHRQ), March 2021. http://dx.doi.org/10.23970/ahrqepctb38.

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Background. Automated-entry consumer devices that collect and transmit patient-generated health data (PGHD) are being evaluated as potential tools to aid in the management of chronic diseases. The need exists to evaluate the evidence regarding consumer PGHD technologies, particularly for devices that have not gone through Food and Drug Administration evaluation. Purpose. To summarize the research related to automated-entry consumer health technologies that provide PGHD for the prevention or management of 11 chronic diseases. Methods. The project scope was determined through discussions with Key Informants. We searched MEDLINE and EMBASE (via EMBASE.com), In-Process MEDLINE and PubMed unique content (via PubMed.gov), and the Cochrane Database of Systematic Reviews for systematic reviews or controlled trials. We also searched ClinicalTrials.gov for ongoing studies. We assessed risk of bias and extracted data on health outcomes, surrogate outcomes, usability, sustainability, cost-effectiveness outcomes (quantifying the tradeoffs between health effects and cost), process outcomes, and other characteristics related to PGHD technologies. For isolated effects on health outcomes, we classified the results in one of four categories: (1) likely no effect, (2) unclear, (3) possible positive effect, or (4) likely positive effect. When we categorized the data as “unclear” based solely on health outcomes, we then examined and classified surrogate outcomes for that particular clinical condition. Findings. We identified 114 unique studies that met inclusion criteria. The largest number of studies addressed patients with hypertension (51 studies) and obesity (43 studies). Eighty-four trials used a single PGHD device, 23 used 2 PGHD devices, and the other 7 used 3 or more PGHD devices. Pedometers, blood pressure (BP) monitors, and scales were commonly used in the same studies. Overall, we found a “possible positive effect” of PGHD interventions on health outcomes for coronary artery disease, heart failure, and asthma. For obesity, we rated the health outcomes as unclear, and the surrogate outcomes (body mass index/weight) as likely no effect. For hypertension, we rated the health outcomes as unclear, and the surrogate outcomes (systolic BP/diastolic BP) as possible positive effect. For cardiac arrhythmias or conduction abnormalities we rated the health outcomes as unclear and the surrogate outcome (time to arrhythmia detection) as likely positive effect. The findings were “unclear” regarding PGHD interventions for diabetes prevention, sleep apnea, stroke, Parkinson’s disease, and chronic obstructive pulmonary disease. Most studies did not report harms related to PGHD interventions; the relatively few harms reported were minor and transient, with event rates usually comparable to harms in the control groups. Few studies reported cost-effectiveness analyses, and only for PGHD interventions for hypertension, coronary artery disease, and chronic obstructive pulmonary disease; the findings were variable across different chronic conditions and devices. Patient adherence to PGHD interventions was highly variable across studies, but patient acceptance/satisfaction and usability was generally fair to good. However, device engineers independently evaluated consumer wearable and handheld BP monitors and considered the user experience to be poor, while their assessment of smartphone-based electrocardiogram monitors found the user experience to be good. Student volunteers involved in device usability testing of the Weight Watchers Online app found it well-designed and relatively easy to use. Implications. Multiple randomized controlled trials (RCTs) have evaluated some PGHD technologies (e.g., pedometers, scales, BP monitors), particularly for obesity and hypertension, but health outcomes were generally underreported. We found evidence suggesting a possible positive effect of PGHD interventions on health outcomes for four chronic conditions. Lack of reporting of health outcomes and insufficient statistical power to assess these outcomes were the main reasons for “unclear” ratings. The majority of studies on PGHD technologies still focus on non-health-related outcomes. Future RCTs should focus on measurement of health outcomes. Furthermore, future RCTs should be designed to isolate the effect of the PGHD intervention from other components in a multicomponent intervention.
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