Relevant bibliographies by topics / HDFC

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'HDFC'

Author: Grafiati
Published: 14 November 2023

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Journal articles on the topic "HDFC"

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Thakur, Neelam, and J. S. Bhatnagar. "Financial analysis of HDFC Bank." Scientific Journal of India 2, no. 2 (December 31, 2017): 53–54. http://dx.doi.org/10.21276/24565644/2017.v2.i2.18.

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Liu, Zeli, Jiuhong Jiang, and Ziling Xu. "Study of the Frost Resistance of HDFC Based on a Response Surface Model and GM (1,1) Model." Advances in Materials Science and Engineering 2022 (January 21, 2022): 1–14. http://dx.doi.org/10.1155/2022/8420785.

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Taking high ductility concrete (HDFC) as a research object, the frost resistance of HDFC in freeze-thaw cycle tests is studied, accurately predicted, and quantitatively described. Taking the relative dynamic elastic modulus as the evaluation index, the response surface model and GM (1,1) model were used to study the frost resistance of HDFC, and the advantages and disadvantages were evaluated. Design-Expert software was used to establish a response surface model to study the effects of polyvinyl alcohol fiber (PVA) length, polyvinyl alcohol fiber volume content, and number of freeze-thaw cycles on the frost resistance of HDFC, and a fitting relationship model between the relative dynamic elastic modulus and these three factors was established. The results show that the influence of PVA fiber content on the frost resistance durability of HDFC is higher than that of the PVA fiber length, but the effect of the external environment on the degree of deterioration for HDFC is greater than the improvement of the properties of the material itself; that is, the freeze-thaw cycling has a greater effect than the PVA fiber content and length. Grey system theory was introduced in the HDFC freezing resistance test, and the change rule for the relative elastic modulus and the average relative error for the GM (1,1) model for varying PVA fiber length and content was determined to be less than 5%. It is concluded that the freezing resistance prediction accuracy for HDFC based on the GM (1,1) model is higher than that of the response surface model. The GM (1,1) model can be used to accurately predict the degree of damage caused by freezing and melting cycles for HDFC.
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Tandon, Deepak, and Dharminder Kumar Batra. "Merger of Hdfc Ltd & Hdfc Bank: Integration for achieving growth." JIMS8M The Journal of Indian Management & Strategy 28, no. 2 (2023): 61–64. http://dx.doi.org/10.5958/0973-9343.2023.00017.0.

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Bharadwaj BP, Prerana, and Radha Pavitra Yalamarti. "A Comparative Study on Financial Performance between Equity and Debt Schemes of HDFC Mutual Funds and SBI Mutual Funds." Journal of Accounting Research, Business and Finance Management 4, no. 1 (June 13, 2023): 41–65. http://dx.doi.org/10.46610/jarbfm.2023.v04i01.005.

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According to research, investment trust businesses provide investors with a variety of programs and assist them in selecting the best one for their needs. Several investments are available to everyone, including stocks, loans, real estate, and others. Companies provide varying returns for each plan, and investors must be well-versed in their investments. Comparing and investing in the systems of the two organizations is therefore beneficial. Companies ought to elevate themselves. Investor returns from HDFC MF are lower than those from SBI MF. In addition, HDFC MF has changed significantly over the last several years. In this study, hybrid equity and debt funds from HDFC and SBI were compared and the five-year results of the two trusts were contrasted that eventually generated profitable returns. In comparison to the HDFC Hybrid Equity Fund, the SBI Hybrid Equity Fund is superior. Due to their higher returns, SBI Hybrid Debt Funds are preferable to HDFC Hybrid Debt Funds. Because of this, SBI's investment trusts are better than HDFC's. SBI funds are the finer option for investors since they produce strong returns.
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K., Subramoniam, and Harishma Hari. "Measuring the Performance Efficiency of State Bank of India and HDFC Bank using Balanced Score Card." SDMIMD Journal of Management 12, no. 2 (October 1, 2021): 11. http://dx.doi.org/10.18311/sdmimd/2021/26371.

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<p>The research article presents performance analysis of the State Bank of India Ltd and the HDFC Bank Ltd using Balanced Score Card (BSC) developed by Robert Kaplan and David Norton. It attempts an analysis to develop a deep understanding of the concept of BSC as a tool for strategy mapping and measurement of performance of a public sector bank and a private sector bank as mentioned elsewhere. BSC is a performance evaluation system not only based upon financial parameters, but also on non-financial aspects like customer indicators, internal business processes and employee learning and growth. Actual performance data from years 2009 to 2019 and business indicators of the year 2020 of the Banks are used for this purpose. The BSC model was developed to address the problems and limitations of relying only on financial measures for strategy formulation and measuring organizational performance. The study revealed that Gross NPA of SBI has increased while that of HDFC Bank has reduced during the period of study. Obviously the ROA is also better for HDFC Bank compared to that of SBI. It is inferred that HDFC Bank has garnered more net profit than SBI during the period of study. HDFC Bank has shown better performance compared to SBI according to the current study. The implication of the study is that both the banks have to visit all the areas of their business to ensure growth in financial performance, better customer service, efficient internal processes and higher learning and growth in the future years. This could ensure better profit management and risk management.</p>
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K., Subramoniam, and Harishma Hari. "Measuring the Performance Efficiency of State Bank of India and HDFC Bank using Balanced Score Card." SDMIMD Journal of Management 12, no. 2 (October 1, 2021): 11. http://dx.doi.org/10.18311/sdmimd/2021/26371.

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<p>The research article presents performance analysis of the State Bank of India Ltd and the HDFC Bank Ltd using Balanced Score Card (BSC) developed by Robert Kaplan and David Norton. It attempts an analysis to develop a deep understanding of the concept of BSC as a tool for strategy mapping and measurement of performance of a public sector bank and a private sector bank as mentioned elsewhere. BSC is a performance evaluation system not only based upon financial parameters, but also on non-financial aspects like customer indicators, internal business processes and employee learning and growth. Actual performance data from years 2009 to 2019 and business indicators of the year 2020 of the Banks are used for this purpose. The BSC model was developed to address the problems and limitations of relying only on financial measures for strategy formulation and measuring organizational performance. The study revealed that Gross NPA of SBI has increased while that of HDFC Bank has reduced during the period of study. Obviously the ROA is also better for HDFC Bank compared to that of SBI. It is inferred that HDFC Bank has garnered more net profit than SBI during the period of study. HDFC Bank has shown better performance compared to SBI according to the current study. The implication of the study is that both the banks have to visit all the areas of their business to ensure growth in financial performance, better customer service, efficient internal processes and higher learning and growth in the future years. This could ensure better profit management and risk management.</p>
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Ghosh, Uma, Chandan Singh Adhikari, and Archisman Neogi. "A Comparative Study of Performance of HDFC with select Private and Public Sector banks." Journal of Global Economy 13, no. 2 (June 26, 2017): 147–60. http://dx.doi.org/10.1956/jge.v13i2.457.

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AbstractBanking industry has undergone metamorphosis due to increase in competition from private sector banks, foreign banks as well as payment banks. This increasing competition has kept the banks on tenterhook. While public sector banks due to their own compulsions have amassed huge NPAs, other banks also could not isolate them from this NPAs problem. Last three years, in particular have been bad years for banking industry as a whole. However, HDFC bank has stood out as different player in the banking industry in terms of its stellar performance as measured by various performance indicators. This paper attempts to examine the comparative performance of public sector banks namely Punjab National Bank, Bank of India and Bank of Baroda, and private sector banks such as ICICI Bank, HDFC Bank and AXIS Bank over the last three years. Based on the comparative performance of these banks, it investigates into the tactics and strategies of HDFC Bank, which distinguished it from the other banks during the turbulent times.
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Borthakur, Mrigakshi. "The Service Marketing Mix of HDFC Bank." Shanlax International Journal of Management 9, no. 3 (January 1, 2022): 64–66. http://dx.doi.org/10.34293/management.v9i3.4562.

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Marketing mix simply means placing of the right product or a bundle of products or services at the right place at a reasonable price. For any company to run its business smoothly, it must know every aspect of the line of business it is in and how to use its marketing mix properly to attract customers. The industry made up of companies which earn income from providing services to its customers is called service industry. The major players of the service industry are banking, tourism, transportation, warehousing, distribution, hotels, restaurants, food delivery, etc. This paper would discuss on the ‘marketing mix’ of HDFC bank which happens to be a major player in the banking industry of India.
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Prashanth, Malyala, Mr Venkat Reddy, Mr G. Subbareddy, and DR Venkata Rangaiah. "Consumer Awareness At HDFC Standard Life Insurance." Think India 22, no. 2 (April 16, 2019): 77–82. http://dx.doi.org/10.26643/think-india.v22i2.7960.

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Life insurance is the insurance which is taken on the risks of the person. Though life insurance is in practice for many years in different forms in our country the concept of health insurance in its present form is of very recent origin. The fact that the sector is under penetrated can be known by the fact that less than 20% of the total population is insured for life risks. So there is a huge potentiality which is waiting to being tapped by the insurance companies.
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Kumar, Vishal. "Impact of Emotional Intelligence and Gender on Job Satisfaction: An Empirical Study amongst the Employees of HDFC Banks in Chandigarh Tricity, India." INTERNATIONAL JOURNAL OF INNOVATION AND ECONOMIC DEVELOPMENT 4, no. 2 (2018): 24–31. http://dx.doi.org/10.18775/ijied.1849-7551-7020.2015.42.2002.

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Emotional intelligence is the most significant concept used in the present scenario of the work environment towards the job satisfaction. Nowadays, Emotional intelligence is used as a tool for measuring the organization’s performance and also playing a key role in stress management and job satisfaction of employees. Job dissatisfaction results in higher absenteeism, lower productivity, defensive behavior and lower performance. The study was organized on the employees’ of HDFC banks, working in Chandigarh Tricity to analyze the impact of emotional intelligence and gender on job satisfaction. A descriptive correlational research was conducted, by taking the population of all the employees of HDFC Banks, Chandigarh Tricity. Convenience sampling method was used to select the sample of the study which included 100 respondents from various branches of HDFC banks in Chandigarh Tricity. The inferences of the study were made with the help of statistical tools such as Karl Pearson’s Correlation Coefficient, Regression analysis, t-test, and ANOVA. In the study, it has been observed that both emotional intelligence and job satisfaction has a positive relationship. It also indicates that Gender has no significant impact on these variables.
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Dissertations / Theses on the topic "HDFC"

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Ozdarska, Katarzyna. "Synthèses d’inhibiteurs de HDAC et leurs tests biologiques (Cytotoxicité, HDAC inhibition)." Thesis, Reims, 2020. http://www.theses.fr/2020REIMS023.

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L’épigénétique représente les modifications de l’expression génique, sans altérer la séquence nucléique de l'ADN. L'un des mécanismes de régulation est le remodelage de la chromatine qui s’effectue via les histones acétyltransférases et les histones désacétylases (HDAC) permettant ou non la transcription de gènes. Une expression anormale des HDAC est corrélée à de nombreuses maladies (dépendance à l'alcool, inflammation ainsi que les maladies cardiovasculaires et neurodégénératives, cancers…). Il est primordial de cibler la sélectivité d’une isoforme parmi les 11 connues des HDAC zinc dépendantes pour éviter les effets secondaires. Le but de la recherche était de concevoir et de synthétiser de nouveaux composés, de vérifier leur activité inhibitrice vis-à-vis des HDAC de classe I ou II et leur cytotoxicité sur quatre lignées cellulaires: HaCaT, V79-4, SH-SY5Y et PC12. Ainsi, nous nous sommes concentrés sur les pharmacomodulations du ZBG, de l’espaceur et de la tête de molécules connues tels que le MS-275 (sélectif de la classe I des HDAC), les SAHA et TSA (espaceur en C5 ou C6) avec une forte activité inhibitrice vis-à-vis des HDAC, mais non sélectifs. Nous nous sommes concentrés sur les pharmacomodulations de l'HDACI connu modifiant le domaine de liaison au zinc ZBG (sulfonylhydrazide, catéchol), la nature de l’espaceur (alkyl, aryl) et le groupe de reconnaissance de surface (bis-aryl, adamantyl, indolopyridazinone). Une bibliothèque de 57 nouveaux composés a été créée en trois séries. Aucun d'entre eux n'a montré d'activité inhibitrice satisfaisante. Les composés sélectionnés n'ont pas montré d'activité cytotoxique sur les lignées de cellules neuronales. Sur la base de cette recherche, il est possible de créer de nouveaux composés dans la série indolopyridazinone afin de les tester
Epigenetics represents changes in gene expression without altering the nucleic sequence of DNA. One of the main mechanisms of regulation of gene expression is chromatin remodeling via histone acetyltransferases and histone deacetylases (HDAC), which may or may not allow gene transcription. An abnormal expression of HDACs is correlated with many diseases (alcohol dependence, inflammation as well as cardiovascular and neurodegenerative diseases, cancers...). It is essential to target the selectivity of one isoform among the 11 known zinc-dependent HDACs to avoid side effects. The aim of the research was to design and synthesize new compounds, verify their inhibitory activity against class I or II HDACs and their cytotoxicity on four cell lines: HaCaT, V79-4, SH-SY5Y and PC12. We focused on the pharmacomodulations of ZBG, the linker and the cap of known molecules such as MS-275 (selective for class I of HDACs), SAHA and TSA (spacer in C5 or C6) with a strong inhibitory activity towards HDACs, but not selective. We concentrated on the pharmacomodulations of known HDACI modifying the zinc binding domain (sulfonylhydrazide, catechol), the nature of the spacer (alkyl, aryl) and the surface recognition group (bis-aryl, adamantyl, indolopyridazinone). A library of 57 new compounds was designed in three series. None of them showed satisfactory inhibitory activity. The selected compounds did not show cytotoxic activity on neuronal cell lines. Based on this research, it is possible to create new compounds in the indolopyridazinone series in order to test them
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Silva, Fernández Simón Yeco. "Photometric Redshifts in the HDFS." Tesis, Universidad de Chile, 2015. http://repositorio.uchile.cl/handle/2250/133104.

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Magíster en Ciencias, Mención Astronomía
Se presenta fotometría óptica en 11 bandas medias a partir de observaciones realizadas con el telescopio de 2.2m en LSO (WFI) sobre un campo de ~30'×30' deg extendido en el Hubble Deep Field-South (EHDF-S), el cual es uno de los campos que contiene información en multibandas como parte del Multiwavelength Survey by Yale-Chile (MUSYC). Este campo tiene una gran cantidad de datos públicos y datos auxiliares en bandas UV, óptico, infrarrojo cercano e infrarrojo lejano. Se determinaron aperturas óptimas para fotometría de alta precisión para diversas fuentes y brillos. Se proporcionan incertezas en magnitud a través de una técnica mejorada que considera correlaciones a mayor y menor escala en el ruido. Se incluyen datos auxiliares en el óptico a partir del catálogo de MUSYC en bandas UBVRIz ' hasta una magnitud total de R=25 (AB), además de datos en infrarrojo cercano JHK de dos campos de 10 '× 10' deg con profundidades de J~22.5, H~21.5 y K~21 (5σ; Vega). Se creó un catálogo fotométrico de ~62.000 galaxias detectadas en la imagen BVR de MUSYC. Se miden redshifts fotométricos mediante el código EAzY y se compara con ~500 fuentes identificadas espectroscópicamente con la finalidad de probar la precisión y desempeño de los filtros en bandas medias. Los redshifts fotométricos resultaron más confiables para R<24 cuando la muestra contiene ~12.000 galaxias, particularmente en 0.1 < z < 1.2, región de sampleo en el óptico de características como el quiebre de Balmer. La precisión de los redshifts fotométricos en Δz/(1+z) es de 0.029, lo cual es comparable a estudios recientes con un mejoramiento del 20%. Estos valores se degradan en calidad para galaxias más débiles o cuando se utilizan menos bandas. Como demostración de la calidad de los resultados, se derivan tipos espectrales de las fuentes, luego se construyen funciones de luminosidad para comparar con trabajos similares, y así confirmar la fuerte dependencia de las SEDs con la densidad numérica de fuentes. Se incorporan datos observacionales en radio en el HDFS del Australia Telescopio Hubble Deep Field-South para estudiar en detalle su población. Este proyecto realizó observaciones en cuatro longitudes de onda, 20, 11, 6 y 3 cm y alcanza una sensibilidad en rms alrededor de 10 μJy para cada longitud de onda. Utilizando una muestra de 227 fuentes en radio seleccionadas, se realiza una clasificación detallada de la población en AGNs (-loud de radio (9%) y -quiet (46%)), galaxias con formación estelar (SFG; 39%), y galaxias normales (6%), usando los redshifts fotométricos, información en multibanda, un template combinado quasares, índices espectrales, las SEDs derivadas y la dependencia redshift luminosidad. Se confirman los resultados recientes sobre la disribución de AGNs y SFGs. Asimismo las LFs muestran consistencia para las fuentes en radio para z~1.0. Los resultados obtenidos siguen la tendencia de los trabajos previos de los últimos 4 a 5 años en la distribución de las fuentes de radio, y sugiere nuevas metodologías en torno a la caracterizacón la población en radio.
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Khan, Omar Ali. "HR23B, a biomarker for HDAC inhibitors." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:9cd76c0b-e70e-43f7-a92d-a99f403a077e.

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As our understanding of cancer biology increases and novel therapies are developed, an increasing number of predictive biomarkers are becoming clinically available. Aberrant acetylation has been strongly linked to tumourigenesis and the modulation of acetylation through targeting histone deacetylase (HDAC) has led to the introduction of many HDAC inhibitors. To date, two have had regulatory approval for the treatment of cutaneous T cell lymphoma (CTCL). Modifications in chromatin control underpin the mechanism of action of HDAC inhibitors. A genome wide loss-of-function screen identified HR23B as a gene that governs sensitivity to HDAC inhibitors. HR23B shuttles ubiquitinated cargo proteins to the proteasome and elevated levels may contribute to cell death mediated by this pathway. It also governs cell sensitivity to drugs that act directly on the proteasome. HDAC inhibitors influence proteasome activity and there may be a synergistic interaction with proteasome inhibitors. HR23B and HDAC6 interact and HDAC6 may be a negative regulator of apoptosis and a positive regulator of autophagy and through its ability to down-regulate HR23B, may impact on the cellular outcome of HDAC inhibitor treatment. Expression of HR23B has been correlated with clinical response to HDAC inhibitors in a retrospective analysis of CTCL patients. The tissue expression of HR23B and the autophagy marker LC3 has been investigated and there may be a reciprocal relationship in their expression in some tumours which may provide prognostic information and patients with low HR23B expression but high levels of autophagy appear to have a particularly poor prognosis. Well designed, biomarker-driven prospective clinical trials are needed to clarify the predictive and prognostic roles of HR23B.
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Polášek, Jaromír. "Implementace protokolu HDLC v síťových simulátorech." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2018. http://www.nusl.cz/ntk/nusl-377008.

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This diploma thesis deals with the possibility of using HDLC (High-Level Data Link Control) protocol for communication and addressing of smart metering devices with a data concentrator. The HDLC protocol is used in two DLMS/COSEM (Device Language Message Specification/Companion Specification for Energy Metering) communication profiles. To simulate these communication profiles, the most appropriate simulation program is selected. Using this simulator, the first communication profile is implemented and the second one is designed. Communication profile based on TCP/IP (Transmission Control Protocol/Internet Protocol) has been fully implemented. To implement the three-layer HDLC communication profile, all options have been thoroughly explored. Using these findings, a process was designed to guide the full implementation. For the first communication profile the qualitative parameters are measured, which are then plotted and evaluated.
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Careres, Gutierrez Franco Jesus. "Towards an S3-based, DataNode-lessimplementation of HDFS." Thesis, KTH, Skolan för elektroteknik och datavetenskap (EECS), 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-291125.

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The relevance of data processing and analysis today cannot be overstated. The convergence of several technological advancements has fostered the proliferation of systems and infrastructure that together support the generation, transmission, and storage of nearly 15,000 exabytes of digital, analyzabledata. The Hadoop Distributed File System (HDFS) is an open source system designed to leverage the storage capacity of thousands of servers, and is the file system component of an entire ecosystem of tools to transform and analyze massive data sets. While HDFS is used by organizations of all sizes, smaller ones are not as well-suited to organically grow their clusters to accommodate their ever-expanding data sets and processing needs. This is because larger clusters are concomitant with higher investment in servers, greater rates of failures to recover from, and the need to allocate moreresources in maintenance and administration tasks. This poses a potential limitation down the road for organizations, and it might even deter some from venturing into the data world altogether. This thesis addresses this matter by presenting a novel implementation of HopsFS, an already improved version of HDFS, that requires no user-managed data servers. Instead, it relies on S3, a leading object storage service, for all its user-data storage needs. We compared the performance of both S3-based and regular clusters and found that such architecture is not only feasible, but also perfectly viable in terms of read and write throughputs, in some cases even outperforming its original counterpart. Furthermore, our solution provides first-class elasticity, reliability, and availability, all while being remarkably more affordable.
Relevansen av databehandling och analys idag kan inte överdrivas. Konvergensen av flera tekniska framsteg har främjat spridningen av system och infrastruk-tur som tillsammans stöder generering, överföring och lagring av nästan 15,000 exabyte digitala, analyserbara data. Hadoop Distributed File System (HDFS) är ett öppen källkodssystem som är utformat för att utnyttja lagringskapaciteten hos tusentals servrar och är filsystemkomponenten i ett helt ekosystem av verktyg för att omvandla och analysera massiva datamängder. HDFS används av organisationer i alla storlekar, men mindre är inte lika lämpade för att organiskt växa sina kluster för att tillgodose deras ständigt växande datamängder och behandlingsbehov. Detta beror på att större kluster är samtidigt med högre investeringar i servrar, större misslyckanden att återhämta sig från och behovet av att avsätta mer resurser i underhålls- och administrationsuppgifter. Detta utgör en potentiell begränsning på vägen för organisationer, och det kan till och med avskräcka en del från att våga sig helt in i datavärlden. Denna avhandling behandlar denna fråga genom att presentera en ny implementering av HopsFS, en redan förbättrad version av HDFS, som inte kräver några användarhanterade dataservrar. Istället förlitar sig det på S3, en ledande objektlagringstjänst, för alla dess användardata lagringsbehov. Vi jämförde prestandan för både S3-baserade och vanliga kluster och fann att sådan arkitektur inte bara är möjlig, utan också helt livskraftig när det gäller läs- och skrivgenomströmningar, i vissa fall till och med bättre än dess ursprungliga motsvarighet. Dessutom ger vår lösning förstklassig elasticitet, tillförlitlighet och tillgänglighet, samtidigt som den är anmärkningsvärt billigare.
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Schreiner, Lindsay Marie. "HDAC Mediated Integration of NF-¿B Transcriptional Regulation." University of Toledo / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1404744801.

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Alqahtani, Abdulateef Alqarni. "Synthesis and Biological Evaluation of New HDAC Inhibitors." University of Toledo / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1525448898248748.

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Sindi, Shaimaa Hesham. "Guanidine- Based HDAC-Inhibitors as Anti-Cancer Agents." University of Toledo / OhioLINK, 2019. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1564676186975875.

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Perin, Stefano <1995&gt. "Sintesi di inibitori peptidici per interazione MEF2-HDAC." Master's Degree Thesis, Università Ca' Foscari Venezia, 2021. http://hdl.handle.net/10579/19004.

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I peptidi sono sempre più impiegati come agenti terapeutici per diverse malattie. Possiedono caratteristiche intermedie tra i farmaci chimici e biologici come dimensioni inferiori, sintetizzabili chimicamente, facilmente modificabili, con bassa tossicità, antigenicità ridotta, affinità di legame e specificità. Queste caratteristiche uniche li rendono una modalità attraente per lo sviluppo di inibitori di interazioni proteina-proteina. Lo scopo del progetto è sviluppare nuovi inibitori a base di peptidi in grado di bloccare l’interazione del fattore di trascrizione “myocyte enhancer 2” (MEF2) con alcuni membri della classe IIa delle istone deacetilasi (HDAC), una sottofamiglia di quattro proteine (HDAC4, HDAC5, HDAC7 e HDAC9) che sono state collegate ad una varietà di tumori solidi ed ematologici. A tal fine sono stati prodotti una serie di peptidi HDAC della classe II impiegando un sistema automatizzato di sintesi peptidica su fase solida, purificati con HPLC su fase inversa e caratterizzati via spettroscopia di massa e dicroismo circolare. L’affinità di legame dei peptidi verso MEF2 è stata testata con saggi di Polarizzazione di Fluorescenza. Infine l’affinità di legame di un peptide è stata incrementata inserendo una struttura sintetica intramolecolare (un braccio), che aiuta a bloccare il peptide in una conformazione specifica, in modo tale da ridurre l’entropia conformazionale.
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Sodji, Quaovi Hemeka. "Improving histone deacetylase inhibition therapy through isoform selectivity and targeted delivery." Diss., Georgia Institute of Technology, 2014. http://hdl.handle.net/1853/53445.

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Histone deacetylase (HDAC) inhibition has recently emerged as a novel therapy for cancer treatment. However, currently approved histone deacetylase inhibitors (HDACi) are pan-inhibitors thus inhibiting all 11 zinc dependent HDAC isoforms including those not involved in tumorigenesis. These inhibitors are also associated with various side effects including a potentially fatal cardiotoxicity. To address these issues, isoform selective HDACi were designed and synthesized. The use of 3-hydroxy-pyridin-2-thione (3HPT) as zinc chelation group resulted in small molecules devoid of HDAC1 inhibition but active against HDAC6 and/or 8. Selected 3HPT containing HDACi displayed anticancer activity against various cancer cell lines including DU145, LNCaP and Jurkat. Surprisingly, the lead-compounds were very potent against Jurkat Jγ cells which are resistant to SAHA-induced apoptosis. HDACi were also targeted to cancer cells using folic or pteroic acids as targeting groups. Incorporation of the folic acid into the HDACi pharmacophoric model resulted in inhibitors selective for HDAC6, whereas pteroic-based HDACi inhibited both HDAC1 and 6. Only the pteroic-based inhibitors displayed anticancer activities against folate receptor overexpressing tumors such KB and HeLa. Furthermore, cell-based studies established the inhibition of HDAC1 as the basis for the anticancer activities of the pteroic-based HDACi.
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Books on the topic "HDFC"

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Robert, Buckley, United States. Agency for International Development., and Housing Development Finance Corporation, eds. Private housing finance for low-income households in India: Final analysis of the Housing Guaranty (HG-002) Project with the Housing Development Finance Corporation,Ltd.(HDFC). Washington, D.C: The Urban Institute, 1989.

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Krämer, Oliver H., ed. HDAC/HAT Function Assessment and Inhibitor Development. New York, NY: Springer US, 2023. http://dx.doi.org/10.1007/978-1-0716-2788-4.

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Krämer, Oliver H., ed. HDAC/HAT Function Assessment and Inhibitor Development. New York, NY: Springer New York, 2017. http://dx.doi.org/10.1007/978-1-4939-6527-4.

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Farley, Mark. A computer assisted learning package for the HDLC protocol. [s.l: The author], 1999.

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Y, Li Jason, and Goddard Space Flight Center, eds. The cloud absorption radiometer HDF data user's guide. Greenbelt, Md: National Aeronautics and Space Administration, Goddard Space Flight Center, 1997.

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Y, Li Jason, and Goddard Space Flight Center, eds. The cloud absorption radiometer HDF data user's guide. Greenbelt, Md: National Aeronautics and Space Administration, Goddard Space Flight Center, 1997.

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The HDC in Aceh: Promises and Pitfalls of NGO Mediation and Implementation. Washington, DC: East-West Center Washington, 2004.

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Institution, British Standards. High-level data link control (HDLC) procedures =: Procédures de commande de liaison de données a hautniveau = Bitorientiertes Steuerungsverfahren zur Datenübermittlung. London: BSI, 1985.

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Institution, British Standards. High-level data link control (HDLC) procedures =: Procédures de commande de liaison de données a hautniveau = Bitorientiertes Steuerungsverfahren zur Datenübermittlung. London: BSI, 1985.

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Institution, British Standards. High-level data link control (HDLC) procedures =: Procédures de commande de liaisonde données a haut niveau = Bitorientiertes Steuerungsverfahren zur Datenübermittlung. London: BSI, 1985.

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Book chapters on the topic "HDFC"

1

Fuloria, Sanjay. "HDFC Bank." In Doing Business in South Asia, 53–56. London: Routledge, 2023. http://dx.doi.org/10.4324/9781003261155-10.

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Buchanan, W. J. "HDLC." In The Complete Handbook of the Internet, 451–59. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-0-306-48331-8_20.

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Buchanan, Bill. "HDLC." In Handbook of Data Communications and Networks, 571–79. Boston, MA: Springer US, 1999. http://dx.doi.org/10.1007/978-1-4757-0905-6_44.

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Buchanan, W. J. "HDLC." In The Handbook of Data Communications and Networks, 867–75. Boston, MA: Springer US, 2004. http://dx.doi.org/10.1007/978-1-4020-7870-5_52.

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Koziol, Quincey, Wu-Chun Feng, Wu-Chun Feng, Heshan Lin, Jack Dongarra, Piotr Luszczek, Yale N. Patt, et al. "HDF5." In Encyclopedia of Parallel Computing, 827–33. Boston, MA: Springer US, 2011. http://dx.doi.org/10.1007/978-0-387-09766-4_44.

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Schwab, Manfred. "HDAC Inhibitors." In Encyclopedia of Cancer, 1. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-27841-9_2591-2.

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Olzscha, Heidi, Mina E. Bekheet, Semira Sheikh, and Nicholas B. La Thangue. "HDAC Inhibitors." In Methods in Molecular Biology, 281–303. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3667-0_19.

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Kokubo, Tetsuro. "Mammalian HDAC." In Encyclopedia of Systems Biology, 1173–74. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4419-9863-7_1622.

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Ito, Akihiro, Norikazu Nishino, and Minoru Yoshida. "HDAC Inhibitors." In Histone Deacetylases, 271–97. Totowa, NJ: Humana Press, 2006. http://dx.doi.org/10.1385/1-59745-024-3:271.

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Kwon, Paul, Meier Hsu, Dalia Cohen, and Peter Atadja. "HDAC Inhibitors." In Histone Deacetylases, 315–32. Totowa, NJ: Humana Press, 2006. http://dx.doi.org/10.1385/1-59745-024-3:315.

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Conference papers on the topic "HDFC"

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Fazul, Rhauani Weber Aita, and Patrícia Pitthan Barcelos. "Métricas e Critérios de Disparo para Instrumentar o Balanceamento de Réplicas no HDFS." In Escola Regional de Alto Desempenho da Região Sul. Sociedade Brasileira de Computação - SBC, 2022. http://dx.doi.org/10.5753/eradrs.2022.19173.

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O HDFS Balancer é a solução nativa do Apache Hadoop para o balanceamento de dados por meio de rearranjo de réplicas. Atualmente, é responsabilidade do administrador do sistema monitorar o estado do HDFS e, quando necessário, executar o balanceador. Este trabalho elenca um conjunto de métricas de interesse e critérios de disparo para que o processo de balanceamento de réplicas no HDFS se torne transparente. Por meio das definições apresentadas, as decisões do melhor momento para disparo do HDFS Balancer podem ser automatizadas, removendo a necessidade de intervenção manual.
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Prado, Bruno, Edna Barros, Thiago Figueiredo, and André Aziz. "HdSC." In the 24th symposium. New York, New York, USA: ACM Press, 2011. http://dx.doi.org/10.1145/2020876.2020917.

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Kun Lu, Dong Dai, and Mingming Sun. "HDFS+: Concurrent Writes Improvements for HDFS." In 2013 13th IEEE/ACM International Symposium on Cluster, Cloud and Grid Computing (CCGrid). IEEE, 2013. http://dx.doi.org/10.1109/ccgrid.2013.41.

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Kowalkowski, James, Marc Paterno, and Saba Sehrish. "The Story of HDF5 in High Energy Physics." In The Story of HDF5 in High Energy Physics. US DOE, 2021. http://dx.doi.org/10.2172/1841424.

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Fazul, Rhauani Weber Aita, and Patrícia Pitthan Barcelos. "Estratégia Reativa e Orientada a Eventos para o Balanceamento de Réplicas em um Cluster HDFS." In Anais Estendidos do Simpósio Brasileiro de Engenharia de Sistemas Computacionais. Sociedade Brasileira de Computação - SBC, 2021. http://dx.doi.org/10.5753/sbesc_estendido.2021.18498.

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O HDFS Balancer é a solução oficial para o balanceamento de réplicas no sistema de arquivos distribuído do Hadoop (HDFS). Atualmente, é responsabilidade do administrador do cluster monitorar o estado do sistema e, quando julgar necessário, disparar a execução do balanceador. A configuração e disparo sob demanda do HDFS Balancer, entretanto, apresentam limitações e podem comprometer o propósito do processo. Este trabalho apresenta uma estratégia para o balanceamento reativo que toma ações automáticas baseadas no estado de atividade e inatividade dos nodos. Os resultados obtidos demonstraram que a solução é capaz de reagir adequadamente a eventos de adição e redução de nodos, promovendo o balanceamento de réplicas no HDFS.
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Fazul, Rhauani, and Patrícia Barcelos. "Análise Experimental dos Modos de Balanceamento de Réplicas para o HDFS Balancer." In XXI Escola Regional de Alto Desempenho da Região Sul. Sociedade Brasileira de Computação - SBC, 2021. http://dx.doi.org/10.5753/eradrs.2021.14807.

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O HDFS Balancer é a ferramenta nativa para o balanceamento de réplicas no HDFS. Ao disparar a daemon do balanceador, o administrador do sistema deve definir as configurações a serem utilizadas. De forma a auxiliar a tomada de decisão, este trabalho avalia a aplicabilidade do HDFS Balancer com as configurações recomendadas para três modos de balanceamento: default, background e fast. Os resultados demostram a efetividade de cada modo.
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Fazul, Rhauani Weber Aita, and Patrícia Pitthan Barcelos. "A Confiabilidade dos Racks e a Disponibilidade dos Dados como Métricas para o Balanceamento de Réplicas de um Cluster HDFS." In Simpósio Brasileiro de Redes de Computadores e Sistemas Distribuídos. Sociedade Brasileira de Computação, 2020. http://dx.doi.org/10.5753/sbrc.2020.12269.

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A replicação, embora vital para o bom funcionamento do HDFS, favorece o desbalanceamento do cluster. O HDFS Balancer é uma solução integrada ao Apache Hadoop voltada ao balanceamento de réplicas. O balanceador, entretanto, não é otimizado para atender possíveis demandas de tolerância a falhas e disponibilidade dos dados ao realizar a redistribuição das réplicas. Este trabalho apresenta uma customização para o HDFS Balancer que considera a propensão a falhas dos racks do sistema para definir quais nodos devem receber uma maior ou menor quantidade de dados. Em conjunto, utilizou-se uma prioridade que esforça-se em aumentar a disponibilidade geral dos dados armazenados no HDFS durante o reposicionamento das réplicas no cluster.
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Fazul, Rhauani W., and Patricia Pitthan Barcelos. "Política Customizada de Balanceamento de Réplicas para o HDFS Balancer do Apache Hadoop." In XX Workshop de Testes e Tolerância a Falhas. Sociedade Brasileira de Computação - SBC, 2019. http://dx.doi.org/10.5753/wtf.2019.7717.

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Data replication is a fundamental mechanism of the Hadoop Distributed File System (HDFS). However, the way data is spread across the cluster directly affects the replication balancing. The HDFS Balancer is a Hadoop integrated tool which can balance the storage load on each machine by moving data between nodes, although its operation does not address the specific needs of applications while performing block rearrangement. This paper proposes a customized balancing policy for HDFS Balancer based on a system of priorities, which can be adapted and configured according to usage demands. The priorities define whether HDFS parameters, or whether cluster topology should be considered during the operation, thus making the balancing more flexible.
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Fazul, Rhauani Weber Aita, and Patrícia Pitthan Barcelos. "O Balanceamento de Réplicas no HDFS frente a aplicações com uso intensivo de E/S, dados e CPU." In Anais Estendidos do Simpósio Brasileiro de Engenharia de Sistemas Computacionais. Sociedade Brasileira de Computação - SBC, 2021. http://dx.doi.org/10.5753/sbesc_estendido.2021.18499.

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A replicação de dados é essencial para o sistema de arquivos distribuído do Apache Hadoop (HDFS). Para garantir alta confiabilidade, disponibilidade e desempenho, as réplicas precisam estar armazenadas de forma otimizada pelos nodos do cluster. Entretanto, quando os nodos armazenam quantidades desproporcionais de dados, o funcionamento do sistema é afetado. Visando mitigar os problemas inerentes do desbalanceamento de réplicas, o HDFS Balancer é a solução oficial disponibilizada para a redistribuição dos dados já armazenados no cluster. Neste trabalho, nós avaliamos a efetividade do HDFS Balancer e como o sistema de arquivos explora a localidade dos dados em diferentes situações. Para uma análise aprofundada, aplicações com comportamentos distintos foram consideradas. Os resultados demonstram que o balanceamento de réplicas possibilita otimizações de desempenho significativas no HDFS.
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Fahmy, Mariam Malak, Iman Elghandour, and Magdy Nagi. "CoS-HDFS." In UCC '16: 9th International Conference on Utility and Cloud Computing. New York, NY, USA: ACM, 2016. http://dx.doi.org/10.1145/3006299.3006314.

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Reports on the topic "HDFC"

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Simpson, W., ed. PPP in HDLC Framing. RFC Editor, December 1993. http://dx.doi.org/10.17487/rfc1549.

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Simpson, W., ed. PPP in HDLC-like Framing. RFC Editor, July 1994. http://dx.doi.org/10.17487/rfc1662.

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Josey, Colin James. Converting the MCNP Runtape to HDF5. Office of Scientific and Technical Information (OSTI), September 2019. http://dx.doi.org/10.2172/1566077.

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Miller, Mark, Elena Pourmal, and Elsa Gonsiorowski. PSIP For HDF5 Pilot Project (Final Report). Office of Scientific and Technical Information (OSTI), October 2020. http://dx.doi.org/10.2172/1698291.

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Bormann, C. PPP in a Real-time Oriented HDLC-like Framing. RFC Editor, September 1999. http://dx.doi.org/10.17487/rfc2687.

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Goldstein, Justin, Charles Hammock, Ralph Liu, Jacob Janz, Clyburn Cunningham, and Mitchell Rimerman. Offloading Calculations to Computational Storage Devices: Spark and HDFS. Office of Scientific and Technical Information (OSTI), August 2021. http://dx.doi.org/10.2172/1813800.

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Kulesza, Joel, and Colin Josey. Fission Matrix Processing Using the MCNP6.3 HDF5 Restart File. Office of Scientific and Technical Information (OSTI), May 2022. http://dx.doi.org/10.2172/1867160.

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Priest, R. G., U. R. Obeysekare, and C. J. Williams. Conversion of IRAMMP Data to HDF Format. Fort Belvoir, VA: Defense Technical Information Center, October 1992. http://dx.doi.org/10.21236/ada256515.

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Kulesza, Joel. MCNP® Code Version 6.3.0 Unstructured-mesh HDF5-based Output Verification. Office of Scientific and Technical Information (OSTI), September 2022. http://dx.doi.org/10.2172/1889958.

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Bethel, E. Wes, Luke Gosink, John Shalf, Kurt Stockinger, and Kesheng Wu. HDF5-FastQuery: An API for Simplifying Access to Data Storage,Retrieval, Indexing and Querying. Office of Scientific and Technical Information (OSTI), June 2006. http://dx.doi.org/10.2172/888964.

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