Journal articles on the topic 'HCMEC'
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Zakrzewicz, A., M. Gräfe, D. Terbeek, M. Bongrazio, W. Auch-Schwelk, B. Walzog, K. Graf, E. Fleck, K. Ley, and P. Gaehtgens. "L-Selectin–Dependent Leukocyte Adhesion to Microvascular But Not to Macrovascular Endothelial Cells of the Human Coronary System." Blood 89, no. 9 (May 1, 1997): 3228–35. http://dx.doi.org/10.1182/blood.v89.9.3228.
Full textMarquez-Curtis, Leah A., Reid Bokenfohr, Locksley E. McGann, and Janet A. W. Elliott. "Cryopreservation of human cerebral microvascular endothelial cells and astrocytes in suspension and monolayers." PLOS ONE 16, no. 4 (April 14, 2021): e0249814. http://dx.doi.org/10.1371/journal.pone.0249814.
Full textMeli, Athinoula, Ann McCormack, Ianina Conte, Qu Chen, James Streetley, Marlene L. Rose, Ruben Bierings, et al. "Altered Storage and Function of von Willebrand Factor in Human Cardiac Microvascular Endothelial Cells Isolated from Recipient Transplant Hearts." International Journal of Molecular Sciences 24, no. 5 (February 25, 2023): 4553. http://dx.doi.org/10.3390/ijms24054553.
Full textOmatsu, Tatsushi, Gediminas Cepinskas, Cheril Clarson, Eric K. Patterson, Ibrahim M. Alharfi, Kelly Summers, Pierre-Olivier Couraud, Ignacio A. Romero, Babette Weksler, and Douglas D. Fraser. "CXCL1/CXCL8 (GROα/IL-8) in human diabetic ketoacidosis plasma facilitates leukocyte recruitment to cerebrovascular endothelium in vitro." American Journal of Physiology-Endocrinology and Metabolism 306, no. 9 (May 1, 2014): E1077—E1084. http://dx.doi.org/10.1152/ajpendo.00659.2013.
Full textKhalyfa, Abdelnaby, David Gozal, and Leila Kheirandish-Gozal. "Plasma Extracellular Vesicles in Children with OSA Disrupt Blood–Brain Barrier Integrity and Endothelial Cell Wound Healing In Vitro." International Journal of Molecular Sciences 20, no. 24 (December 10, 2019): 6233. http://dx.doi.org/10.3390/ijms20246233.
Full textSamak, Mostafa, Diana Kaltenborn, Andreas Kues, Ferdinand Le Noble, Rabea Hinkel, and Giulia Germena. "Micro-RNA 92a as a Therapeutic Target for Cardiac Microvascular Dysfunction in Diabetes." Biomedicines 10, no. 1 (December 28, 2021): 58. http://dx.doi.org/10.3390/biomedicines10010058.
Full textRoig-Carles, David, Eduard Willms, Ruud D. Fontijn, Sarai Martinez-Pacheco, Imre Mäger, Helga E. de Vries, Mark Hirst, et al. "Endothelial-Derived Extracellular Vesicles Induce Cerebrovascular Dysfunction in Inflammation." Pharmaceutics 13, no. 9 (September 21, 2021): 1525. http://dx.doi.org/10.3390/pharmaceutics13091525.
Full textCucullo, Luca, Pierre-Olivier Couraud, Babette Weksler, Ignacio-Andres Romero, Mohammed Hossain, Edward Rapp, and Damir Janigro. "Immortalized Human Brain Endothelial Cells and Flow-Based Vascular Modeling: A Marriage of Convenience for Rational Neurovascular Studies." Journal of Cerebral Blood Flow & Metabolism 28, no. 2 (July 4, 2007): 312–28. http://dx.doi.org/10.1038/sj.jcbfm.9600525.
Full textChen, Yanlan, Wen Huang, Wenlin Jiang, Xianghong Wu, Biao Ye, and Xiaoting Zhou. "HIV-1 Tat Regulates Occludin and AβTransfer Receptor Expression in Brain Endothelial Cells via Rho/ROCK Signaling Pathway." Oxidative Medicine and Cellular Longevity 2016 (2016): 1–9. http://dx.doi.org/10.1155/2016/4196572.
Full textChandrasekar, Bysani, Kirankumar Vemula, Rama Mohan Surabhi, Min Li-Weber, Laurie B. Owen-Schaub, Liselotte E. Jensen, and Srinivas Mummidi. "Activation of Intrinsic and Extrinsic Proapoptotic Signaling Pathways in Interleukin-18-mediated Human Cardiac Endothelial Cell Death." Journal of Biological Chemistry 279, no. 19 (February 11, 2004): 20221–33. http://dx.doi.org/10.1074/jbc.m313980200.
Full textIto, Shingo, Mariko Oishi, Seiryo Ogata, Tatsuki Uemura, Pierre-Olivier Couraud, Takeshi Masuda, and Sumio Ohtsuki. "Identification of Cell-Surface Proteins Endocytosed by Human Brain Microvascular Endothelial Cells In Vitro." Pharmaceutics 12, no. 6 (June 23, 2020): 579. http://dx.doi.org/10.3390/pharmaceutics12060579.
Full textZougbédé, Sergine, Florence Miller, Philippe Ravassard, Angelita Rebollo, Liliane Cicéron, Pierre-Olivier Couraud, Dominique Mazier, and Alicia Moreno. "Metabolic Acidosis Induced by Plasmodium Falciparum Intraerythrocytic Stages Alters Blood—Brain Barrier Integrity." Journal of Cerebral Blood Flow & Metabolism 31, no. 2 (August 4, 2010): 514–26. http://dx.doi.org/10.1038/jcbfm.2010.121.
Full textTai, Leon M., A. Jane Loughlin, David K. Male, and Ignacio A. Romero. "P-Glycoprotein and Breast Cancer Resistance Protein Restrict Apical-to-Basolateral Permeability of Human Brain Endothelium to Amyloid-β." Journal of Cerebral Blood Flow & Metabolism 29, no. 6 (April 15, 2009): 1079–83. http://dx.doi.org/10.1038/jcbfm.2009.42.
Full textDal Magro, Roberta, Agostina Vitali, Stefano Fagioli, Alberto Casu, Andrea Falqui, Beatrice Formicola, Lorenzo Taiarol, et al. "Oxidative Stress Boosts the Uptake of Cerium Oxide Nanoparticles by Changing Brain Endothelium Microvilli Pattern." Antioxidants 10, no. 2 (February 9, 2021): 266. http://dx.doi.org/10.3390/antiox10020266.
Full textBecker, Guillaume, Sylvia Da Silva, Amelia-Naomi Sabo, Maria Cristina Antal, Véronique Kemmel, and Laurent Monassier. "Blood–Brain Barrier Permeability: Is 5-Hydroxytryptamine Receptor Type 4 a Game Changer?" Pharmaceutics 13, no. 11 (November 3, 2021): 1856. http://dx.doi.org/10.3390/pharmaceutics13111856.
Full textLuissint, Anny-Claude, Christian Federici, François Guillonneau, Fabrice Chrétien, Luc Camoin, Fabienne Glacial, Kayathiri Ganeshamoorthy, and Pierre-Olivier Couraud. "Guanine Nucleotide-Binding Protein Gαi2: A New Partner of Claudin-5 that Regulates Tight Junction Integrity in Human Brain Endothelial Cells." Journal of Cerebral Blood Flow & Metabolism 32, no. 5 (February 15, 2012): 860–73. http://dx.doi.org/10.1038/jcbfm.2011.202.
Full textPinto, Miguel, Carlos Fernandes, Eva Martins, Renata Silva, Sofia Benfeito, Fernando Cagide, Ricardo F. Mendes, et al. "Boosting Drug Discovery for Parkinson’s: Enhancement of the Delivery of a Monoamine Oxidase-B Inhibitor by Brain-Targeted PEGylated Polycaprolactone-Based Nanoparticles." Pharmaceutics 11, no. 7 (July 12, 2019): 331. http://dx.doi.org/10.3390/pharmaceutics11070331.
Full textMarqués, Javier, Joaquín Fernández-Irigoyen, Elena Ainzúa, María Martínez-Azcona, Adriana Cortés, Carmen Roncal, Josune Orbe, Enrique Santamaría, and Guillermo Zalba. "NADPH Oxidase 5 (NOX5) Overexpression Promotes Endothelial Dysfunction via Cell Apoptosis, Migration, and Metabolic Alterations in Human Brain Microvascular Endothelial Cells (hCMEC/D3)." Antioxidants 11, no. 11 (October 29, 2022): 2147. http://dx.doi.org/10.3390/antiox11112147.
Full textHaarmann, Axel, Michael Schuhmann, Christine Silwedel, Camelia-Maria Monoranu, Guido Stoll, and Mathias Buttmann. "Human Brain Endothelial CXCR2 is Inflammation-Inducible and Mediates CXCL5- and CXCL8-Triggered Paraendothelial Barrier Breakdown." International Journal of Molecular Sciences 20, no. 3 (January 30, 2019): 602. http://dx.doi.org/10.3390/ijms20030602.
Full textWu, Dongsheng, Camilla Cerutti, Miguel A. Lopez-Ramirez, Gareth Pryce, Josh King-Robson, Julie E. Simpson, Susanne MA van der Pol, et al. "Brain Endothelial miR-146a Negatively Modulates T-Cell Adhesion through Repressing Multiple Targets to Inhibit NF-κB Activation." Journal of Cerebral Blood Flow & Metabolism 35, no. 3 (March 2015): 412–23. http://dx.doi.org/10.1038/jcbfm.2014.207.
Full textGrossen, Philip, Gabriela Québatte, Dominik Witzigmann, Cristina Prescianotto-Baschong, Le-Ha Dieu, and Jörg Huwyler. "Functionalized Solid-Sphere PEG-b-PCL Nanoparticles to Target Brain Capillary Endothelial CellsIn Vitro." Journal of Nanomaterials 2016 (2016): 1–13. http://dx.doi.org/10.1155/2016/7818501.
Full textSorosina, Melissa, Silvia Peroni, Elisabetta Mascia, Silvia Santoro, Ana Maria Osiceanu, Laura Ferrè, Ferdinando Clarelli, et al. "Involvement of NINJ2 Protein in Inflammation and Blood–Brain Barrier Transmigration of Monocytes in Multiple Sclerosis." Genes 13, no. 11 (October 25, 2022): 1946. http://dx.doi.org/10.3390/genes13111946.
Full textHasseli, R., M. M. Fürst, P. Singh, U. Müller-Ladner, M. Kaps, F. Blaes, T. Gerriets, and M. Tschernatsch. "AB0157 IGG FROM PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS AND SYSTEMIC SCLEROSIS HAVE AN INFLUENCE ON COAGULATION FACTORS IN HUMAN CEREBRAL MICROVASCULAR ENDOTHELIAL CELLS IN-VITRO." Annals of the Rheumatic Diseases 79, Suppl 1 (June 2020): 1379. http://dx.doi.org/10.1136/annrheumdis-2020-eular.2631.
Full textLu, Yan, Zhendong Xu, Fuyi Shen, Rong Lin, Haibing Li, Xiang Lv, and Zhiqiang Liu. "Propofol Protects Against TNF-α-induced Blood-brain Barrier Disruption via the PIM-1/eNOS/NO Pathway." Current Neurovascular Research 17, no. 4 (December 14, 2020): 471–79. http://dx.doi.org/10.2174/1567202617999200819142021.
Full textGoeritzer, Madeleine, Eva Bernhart, Ioanna Plastira, Helga Reicher, Christina Leopold, Thomas O. Eichmann, Gerald Rechberger, et al. "Myeloperoxidase and Septic Conditions Disrupt Sphingolipid Homeostasis in Murine Brain Capillaries In Vivo and Immortalized Human Brain Endothelial Cells In Vitro." International Journal of Molecular Sciences 21, no. 3 (February 9, 2020): 1143. http://dx.doi.org/10.3390/ijms21031143.
Full textAjikumar, Anjana, Merete B. Long, Paul R. Heath, Stephen B. Wharton, Paul G. Ince, Victoria C. Ridger, and Julie E. Simpson. "Neutrophil-Derived Microvesicle Induced Dysfunction of Brain Microvascular Endothelial Cells In Vitro." International Journal of Molecular Sciences 20, no. 20 (October 22, 2019): 5227. http://dx.doi.org/10.3390/ijms20205227.
Full textPark, Jee Hyun, Oriana E. Hawkins, Navin K. Chintala, Jon A. Weidanz, and Ulrich Bickel. "Internalization of T-Cell Receptor Mimic Antibody RL6A by Brain Derived Endothelial Cells Analyzed by Flow Cytometry." Journal of Immunology 196, no. 1_Supplement (May 1, 2016): 214.12. http://dx.doi.org/10.4049/jimmunol.196.supp.214.12.
Full textMarcelo, Gonçalo, Jessica Ariana-Machado, Maria Enea, Helena Carmo, Benito Rodríguez-González, José Luis Capelo, Carlos Lodeiro, and Elisabete Oliveira. "Toxicological Evaluation of Luminescent Silica Nanoparticles as New Drug Nanocarriers in Different Cancer Cell Lines." Materials 11, no. 8 (July 28, 2018): 1310. http://dx.doi.org/10.3390/ma11081310.
Full textDimova, Ivanka, Svetla Danova, Ekaterina Nikolova, and Miglena Koprinarova. "Aloe-emodin triggers ROS and Ca 2+ production and decreases the levels of mitochondrial membrane potential of human brain capillary endothelial cells." International Journal of Phytomedicine 9, no. 3 (September 2, 2017): 511. http://dx.doi.org/10.5138/09750185.2138.
Full textHuang, Wen, Geun Bae Rha, Lei Chen, Melissa J. Seelbach, Bei Zhang, Ibolya E. András, Dennis Bruemmer, Bernhard Hennig, and Michal Toborek. "Inhibition of telomerase activity alters tight junction protein expression and induces transendothelial migration of HIV-1-infected cells." American Journal of Physiology-Heart and Circulatory Physiology 298, no. 4 (April 2010): H1136—H1145. http://dx.doi.org/10.1152/ajpheart.01126.2009.
Full textKurosawa, Toshiki, Yuma Tega, Yasuo Uchida, Kei Higuchi, Hidetsugu Tabata, Takaaki Sumiyoshi, Yoshiyuki Kubo, Tetsuya Terasaki, and Yoshiharu Deguchi. "Proteomics-Based Transporter Identification by the PICK Method: Involvement of TM7SF3 and LHFPL6 in Proton-Coupled Organic Cation Antiport at the Blood–Brain Barrier." Pharmaceutics 14, no. 8 (August 12, 2022): 1683. http://dx.doi.org/10.3390/pharmaceutics14081683.
Full textVu, Kiem, Babette Weksler, Ignacio Romero, Pierre-Olivier Couraud, and Angie Gelli. "Immortalized Human Brain Endothelial Cell Line HCMEC/D3 as a Model of the Blood-Brain Barrier Facilitates In Vitro Studies of Central Nervous System Infection by Cryptococcus neoformans." Eukaryotic Cell 8, no. 11 (September 18, 2009): 1803–7. http://dx.doi.org/10.1128/ec.00240-09.
Full textStephan, Delphine, Anais Roger, Jehanne Aghzadi, Sylvie Carmona, Christophe Picard, Jean-Philippe Dales, and Sophie Desplat-Jégo. "TWEAK and TNFα, Both TNF Ligand Family Members and Multiple Sclerosis-Related Cytokines, Induce Distinct Gene Response in Human Brain Microvascular Endothelial Cells." Genes 13, no. 10 (September 24, 2022): 1714. http://dx.doi.org/10.3390/genes13101714.
Full textBay, Cindy, Gzona Bajraktari-Sylejmani, Walter E. Haefeli, Jürgen Burhenne, Johanna Weiss, and Max Sauter. "Functional Characterization of the Solute Carrier LAT-1 (SLC7A5/SLC2A3) in Human Brain Capillary Endothelial Cells with Rapid UPLC-MS/MS Quantification of Intracellular Isotopically Labelled L-Leucine." International Journal of Molecular Sciences 23, no. 7 (March 26, 2022): 3637. http://dx.doi.org/10.3390/ijms23073637.
Full textPiazzini, Vieri, Elisa Landucci, Giulia Graverini, Domenico Pellegrini-Giampietro, Anna Bilia, and Maria Bergonzi. "Stealth and Cationic Nanoliposomes as Drug Delivery Systems to Increase Andrographolide BBB Permeability." Pharmaceutics 10, no. 3 (August 13, 2018): 128. http://dx.doi.org/10.3390/pharmaceutics10030128.
Full textMarinovic, Iva, Maria Bartosova, Rebecca Herzog, Juan Manuel Sacnun, Conghui Zhang, Robin Hoogenboom, Markus Unterwurzacher, et al. "Understanding Cell Model Characteristics—RNA Expression Profiling in Primary and Immortalized Human Mesothelial Cells, and in Human Vein and Microvascular Endothelial Cells." Cells 11, no. 19 (October 5, 2022): 3133. http://dx.doi.org/10.3390/cells11193133.
Full textKim, Yiyoung, Eun Ji Roh, Hari Prasad Joshi, Hae Eun Shin, Hyemin Choi, Su Yeon Kwon, Seil Sohn, and Inbo Han. "Bazedoxifene, a Selective Estrogen Receptor Modulator, Promotes Functional Recovery in a Spinal Cord Injury Rat Model." International Journal of Molecular Sciences 22, no. 20 (October 12, 2021): 11012. http://dx.doi.org/10.3390/ijms222011012.
Full textHoshi, Yutaro, Yasuo Uchida, Takashi Kuroda, Masanori Tachikawa, Pierre-Olivier Couraud, Takashi Suzuki, and Tetsuya Terasaki. "Distinct roles of ezrin, radixin and moesin in maintaining the plasma membrane localizations and functions of human blood–brain barrier transporters." Journal of Cerebral Blood Flow & Metabolism 40, no. 7 (August 14, 2019): 1533–45. http://dx.doi.org/10.1177/0271678x19868880.
Full textArtus, Cédric, Fabienne Glacial, Kayathiri Ganeshamoorthy, Nicole Ziegler, Maeva Godet, Thomas Guilbert, Stefan Liebner, and Pierre-Olivier Couraud. "The Wnt/Planar Cell Polarity Signaling Pathway Contributes to the Integrity of Tight Junctions in Brain Endothelial Cells." Journal of Cerebral Blood Flow & Metabolism 34, no. 3 (December 18, 2013): 433–40. http://dx.doi.org/10.1038/jcbfm.2013.213.
Full textVeszelka, Szilvia, Mária Mészáros, Gergő Porkoláb, Ágnes Rusznyák, Katalin Szászné Réti-Nagy, Mária A. Deli, Miklós Vecsernyés, Ildikó Bácskay, Judit Váradi, and Ferenc Fenyvesi. "Effects of Hydroxypropyl-Beta-Cyclodextrin on Cultured Brain Endothelial Cells." Molecules 27, no. 22 (November 10, 2022): 7738. http://dx.doi.org/10.3390/molecules27227738.
Full textLiu, Haochen, Yixuan Zhang, Hong Zhang, Sheng Xu, Huimin Zhao, and Xiaoquan Liu. "Aβ-Induced Damage Memory in hCMEC/D3 Cells Mediated by Sirtuin-1." International Journal of Molecular Sciences 21, no. 21 (November 3, 2020): 8226. http://dx.doi.org/10.3390/ijms21218226.
Full textFasler-Kan, Elizaveta, Claudia Suenderhauf, Natasha Barteneva, Birk Poller, Daniel Gygax, and Jörg Huwyler. "Cytokine signaling in the human brain capillary endothelial cell line hCMEC/D3." Brain Research 1354 (October 2010): 15–22. http://dx.doi.org/10.1016/j.brainres.2010.07.077.
Full textYin, Yujie, Qian Zhang, Qifei Zhao, Guoyuan Ding, Cong Wei, Liping Chang, Hongrong Li, et al. "Tongxinluo Attenuates Myocardiac Fibrosis after Acute Myocardial Infarction in Rats via Inhibition of Endothelial-to-Mesenchymal Transition." BioMed Research International 2019 (June 16, 2019): 1–13. http://dx.doi.org/10.1155/2019/6595437.
Full textQin, Lan-hui, Wen Huang, Xue-an Mo, Yan-lan Chen, and Xiang-hong Wu. "LPS Induces Occludin Dysregulation in Cerebral Microvascular Endothelial Cells via MAPK Signaling and Augmenting MMP-2 Levels." Oxidative Medicine and Cellular Longevity 2015 (2015): 1–9. http://dx.doi.org/10.1155/2015/120641.
Full textMkrtchyan, H., S. Scheler, I. Klein, A. Fahr, P. O. Couraud, I. A. Romero, B. Weksler, and T. Liehr. "Molecular Cytogenetic Characterization of the Human Cerebral Microvessel Endothelial Cell Line hCMEC/D3." Cytogenetic and Genome Research 126, no. 4 (2009): 313–17. http://dx.doi.org/10.1159/000253080.
Full textBurghardt, Isabel, Elisa Ventura, Tobias Weiss, Judith Johanna Schroeder, Katharina Seystahl, Christian Zielasek, Dorothee Gramatzki, and Michael Weller. "Endoglin and TGF-β signaling in glioblastoma." Cell and Tissue Research 384, no. 3 (January 20, 2021): 613–24. http://dx.doi.org/10.1007/s00441-020-03323-5.
Full textForcaia, Greta, Beatrice Formicola, Giulia Terribile, Sharon Negri, Dmitry Lim, Gerardo Biella, Francesca Re, Francesco Moccia, and Giulio Sancini. "Multifunctional Liposomes Modulate Purinergic Receptor-Induced Calcium Wave in Cerebral Microvascular Endothelial Cells and Astrocytes: New Insights for Alzheimer’s disease." Molecular Neurobiology 58, no. 6 (January 29, 2021): 2824–35. http://dx.doi.org/10.1007/s12035-021-02299-9.
Full textMa, Xiaoqing, Ho Jun Yun, Kenneth Elkin, Yunliang Guo, Yuchuan Ding, and Guangwen Li. "MicroRNA-29b Suppresses Inflammation and Protects Blood-Brain Barrier Integrity in Ischemic Stroke." Mediators of Inflammation 2022 (August 23, 2022): 1–11. http://dx.doi.org/10.1155/2022/1755416.
Full textJin, Liang, Roger L. Nation, Jian Li, and Joseph A. Nicolazzo. "Species-Dependent Blood-Brain Barrier Disruption of Lipopolysaccharide: Amelioration by ColistinIn VitroandIn Vivo." Antimicrobial Agents and Chemotherapy 57, no. 9 (June 24, 2013): 4336–42. http://dx.doi.org/10.1128/aac.00765-13.
Full textSreekanthreddy, Peddagangannagari, Radka Gromnicova, Heather Davies, James Phillips, Ignacio A. Romero, and David Male. "A three-dimensional model of the human blood-brain barrier to analyse the transport of nanoparticles and astrocyte/endothelial interactions." F1000Research 4 (November 17, 2015): 1279. http://dx.doi.org/10.12688/f1000research.7142.1.
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