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1

Meyer‐Schuman, Rebecca, and Anthony Antonellis. "Evidence for a dominant‐negative mechanism in HARS1 ‐mediated peripheral neuropathy." FEBS Journal 288, no. 1 (September 17, 2020): 91–94. http://dx.doi.org/10.1111/febs.15538.

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2

Galatolo, Daniele, Molly E. Kuo, Patrick Mullen, Rebecca Meyer‐Schuman, Stefano Doccini, Roberta Battini, Maria Lieto, et al. "Bi‐allelic mutations in HARS1 severely impair histidyl‐tRNA synthetase expression and enzymatic activity causing a novel multisystem ataxic syndrome." Human Mutation 41, no. 7 (April 29, 2020): 1232–37. http://dx.doi.org/10.1002/humu.24024.

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3

O'Hanlon, Terrance P., and Frederick W. Miller. "Genomic organization, transcriptional mapping, and evolutionary implications of the human bi-directional histidyl-tRNA synthetase locus (HARS/HARSL)." Biochemical and Biophysical Research Communications 294, no. 3 (June 2002): 609–14. http://dx.doi.org/10.1016/s0006-291x(02)00525-9.

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4

Kuneš, I., M. Baláš, T. Koňasová, D. Zahradník, V. Balcar, O. Špulák, D. Kacálek, and M. Jakl. "Cultivation of speckled alder under harsh mountain conditions." Journal of Forest Science 58, No. 5 (May 21, 2012): 234–44. http://dx.doi.org/10.17221/92/2011-jfs.

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The aims of the paper were as follows: (1) to assess the applicability of speckled alder for pioneer stands on the mountainous clear-cut tracts and (2) to evaluate the effects of slow-release fertilizer on the survival and growth of speckled alder under harsh environmental conditions. On the basis of seven-year results we can presume that speckled alder is a convenient pioneer species that can be cultivated on harsh mountain sites where the climatic extremes need to be alleviated and a layer of surface humus renewed. The initial slow-release fertilization is, nonetheless, highly desirable. As contrasted to the control the surface and planting hole applications of amendment reduced the total seven-year mortality rate by 9.5% and 20.1%, respectively, and the periodic annual height increment (2003–2009) was promoted by 47% and 59%, respectively. Analogous results were obtained when the values of basal stem diameter and crown diameter were compared. As for the method of application, the placement of the slow-release amendment in the planting holes seems to be more efficient mainly in terms of survival promoting. The surface application is, nonetheless, less laborious and also yielded satisfactory results.     
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5

Hardie, J. "Harsh advice?" British Dental Journal 199, no. 8 (October 2005): 483–84. http://dx.doi.org/10.1038/sj.bdj.4812855.

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6

Bethka, Kathy. "Harsh Instructors." Nursing 32, no. 2 (February 2002): 8. http://dx.doi.org/10.1097/00152193-200202000-00003.

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Coleman, Carey. "Harsh Instructors." Nursing 32, no. 2 (February 2002): 8. http://dx.doi.org/10.1097/00152193-200202000-00004.

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8

Gilligan, Paula. "“Harsh Realism”." Television & New Media 14, no. 3 (September 14, 2012): 244–60. http://dx.doi.org/10.1177/1527476412457221.

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9

Scott, Marcia. "Harsh Realities." Psychiatric News 36, no. 7 (April 6, 2001): 40. http://dx.doi.org/10.1176/pn.36.7.0040a.

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10

Sriram, Malathi. "Harsh Realities* by Harsh Mariwala & Guru Charan." SDMIMD Journal of Management 13, no. 1 (March 1, 2022): 75. http://dx.doi.org/10.18311/sdmimd/2022/29622.

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11

Lhuillier, Yves, Maroun Ojail, Alexandre Guerre, Jean-Marc Philippe, Karim Ben Chehida, Farhat Thabet, Caaliph Andriamisaina, Chafic Jaber, and Raphaël David. "HARS." ACM Transactions on Embedded Computing Systems 13, no. 3s (March 2014): 1–25. http://dx.doi.org/10.1145/2517311.

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12

Petsko, Gregory A. "A harsh climate." Genome Biology 10, no. 12 (2009): 114. http://dx.doi.org/10.1186/gb-2009-10-12-114.

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13

Petsko, Gregory A. "A harsh climate." Genome Biology 10, no. 12 (2009): 115. http://dx.doi.org/10.1186/gb-2009-10-12-115.

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14

Tee, Louise. "A HARSH TWILIGHT." Cambridge Law Journal 62, no. 1 (March 1, 2003): 36–39. http://dx.doi.org/10.1017/s0008197303336219.

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15

Axelsen, David V., and Lasse Nielsen. "Harsh and Disrespectful." Social Theory and Practice 46, no. 4 (2020): 657–79. http://dx.doi.org/10.5840/soctheorpract20201025101.

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Many policies hinge on determining whether someone’s situation is due to luck or choice. In political philosophy, this prevalence is mirrored by luck egalitarian theories. But overemphasizing the distinction between luck and choice will lead to tensions with the value of moral agency, on which the distinction is grounded. Here, we argue that the two most common contemporary critiques of luck egalitarianism, holding it to be harsh and disrespectful are best understood as illustrating exactly this tension. Elaborating on this conflict, we argue that it should lead us to modify how luck and choice are used in theories of justice.
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16

Hieber, Mäggi, Christopher T. Robinson, Urs Uehlinger, and J. V. Ward. "Are alpine lake outlets less harsh than other alpine streams?" Fundamental and Applied Limnology 154, no. 2 (May 29, 2002): 199–223. http://dx.doi.org/10.1127/archiv-hydrobiol/154/2002/199.

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17

Van de Vliert, E., and RSJ Tol. "Harsh climate promotes harsh governance (except in cold-dry-wealthy environments)." Climate Research 61, no. 1 (September 2, 2014): 19–28. http://dx.doi.org/10.3354/cr01246.

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18

Wadeson, Barry. "Smacking of harsh reality." Nursing Standard 7, no. 29 (April 7, 1993): 49–51. http://dx.doi.org/10.7748/ns.7.29.49.s57.

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19

Turack, Daniel C., Lucy E. Salyer, Jean-Marie Henckaerts., and Helene Lambert. "Laws Harsh as Tigers." International Migration Review 31, no. 1 (1997): 187. http://dx.doi.org/10.2307/2547266.

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20

Student. "HARSH WORDS FOR PROFESSORS." Pediatrics 84, no. 4 (October 1, 1989): A79. http://dx.doi.org/10.1542/peds.84.4.a79a.

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The professors—working steadily and systematically—have destroyed the university as a center of learning and have desolated higher education, which no longer is higher or much of an education. . . Academic culture is not merely indifferent to teaching, it is actively hostile to it.
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21

Ugeda, Miguel M. "Stable in harsh environments." Nature Materials 18, no. 6 (May 21, 2019): 539–40. http://dx.doi.org/10.1038/s41563-019-0351-2.

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22

Wynia, Matthew K. "Consequentialism and Harsh Interrogations." American Journal of Bioethics 5, no. 1 (January 2005): 4–6. http://dx.doi.org/10.1080/15265160590944085.

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23

SPEVACK, LESLEY ALTON. "Harsh instructors are unacceptable." Nursing 32, no. 6 (June 2002): 12–13. http://dx.doi.org/10.1097/00152193-200206000-00005.

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24

SCHMISEK, TAMI. "More about harsh instructors." Nursing 33, no. 4 (April 2003): 12. http://dx.doi.org/10.1097/00152193-200304000-00008.

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25

Johnson, James Turner. "‘Harsh Love’ and Forgiveness." Studies in Christian Ethics 28, no. 3 (August 2015): 266–72. http://dx.doi.org/10.1177/0953946814565304.

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26

Seton-Rogers, Sarah. "Adapting to harsh conditions." Nature Reviews Cancer 16, no. 10 (August 26, 2016): 617. http://dx.doi.org/10.1038/nrc.2016.98.

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27

DeLong, E. F. "Life in Harsh Habitats." Science 263, no. 5145 (January 21, 1994): 401–2. http://dx.doi.org/10.1126/science.263.5145.401.

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28

Berkowitz, Roger. "Book Review: Harsh Justice." Law, Culture and the Humanities 1, no. 1 (February 2005): 132–34. http://dx.doi.org/10.1191/1743872105lw009xx.

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29

Cox, Bev. "A very harsh judgment." Practice Nursing 20, no. 5 (May 2009): 218–20. http://dx.doi.org/10.12968/pnur.2009.20.5.41979.

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30

Black, John H. "Molecules in harsh environments." Faraday Discussions 109 (1998): 257–66. http://dx.doi.org/10.1039/a800591e.

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31

Amir, Ayala. "Harsh and Hopeful World." American Book Review 33, no. 4 (2012): 5. http://dx.doi.org/10.1353/abr.2012.0121.

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32

BRADLEY, BEN. "Doing Away with Harm1." Philosophy and Phenomenological Research 85, no. 2 (September 2012): 390–412. http://dx.doi.org/10.1111/j.1933-1592.2012.00615.x.

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33

Larue, Jean-François. "Precise Under Harsh Conditions." Optik & Photonik 11, no. 2 (April 2016): 35–37. http://dx.doi.org/10.1002/opph.201600014.

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34

Ylimaula, Anna-Maija. "Reaching beyond harsh conditions." Habitat International 13, no. 2 (January 1989): 55–60. http://dx.doi.org/10.1016/0197-3975(89)90066-0.

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35

Hautamäki, Lauri. "Harsh areas in Finland." Habitat International 13, no. 2 (January 1989): 77–85. http://dx.doi.org/10.1016/0197-3975(89)90069-6.

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36

YU, M., C. HUANG, M. XIANG, J. LAI, H. YANG, M. MA, and D. TAN. "hARD1 Antiserum Preparation and Primary Immunohistochemical Analysis of hARD1 in Tumor Tissues." Chinese Journal of Biotechnology 24, no. 7 (July 2008): 1155–61. http://dx.doi.org/10.1016/s1872-2075(08)60057-6.

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37

Jiménez Flores, Juan, Luz María Flores Herrera, and César Merino-Soto. "Factores de riesgo familiares y prácticas de disciplina severa que predicen la conducta agresiva infantil." Liberabit: Revista Peruana de Psicología 25, no. 2 (December 15, 2019): 195–212. http://dx.doi.org/10.24265/liberabit.2019.v25n2.05.

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38

Kuneš, I., D. Zahradník, V. Balcar, O. Špulák, M. Baláš, T. Koňasová, D. Kacálek, et al. "Effects of fertilisation on biomass of Norway spruce on a harsh mountain site." Journal of Forest Science 59, No. 1 (February 12, 2013): 8–21. http://dx.doi.org/10.17221/54/2012-jfs.

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The organic matter produced and accumulated by plants is a crucial component in the ecosystems on environmentally disturbed sites. The aim of our study was to evaluate the influence of initial fertilising on the aboveground and belowground tree biomass of Norway spruce. The biomass amount, distribution and chemical composition were studied in a young spruce stand growing on an acidified mountain clear-cut tract. The fertilised trees accumulated a higher amount of tree biomass. They nonetheless showed lower concentrations of P, N, and K in some root compartments than control trees, which could be ascribed to a dilution effect. As for the aboveground compartments, no significant differences in element concentrations were proved.
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39

Myatt, Rebecca, and Tom Treasure. "Lung cancer: the harsh reality." Cancer Nursing Practice 1, no. 9 (November 2002): 10–11. http://dx.doi.org/10.7748/cnp2002.11.1.9.10.c46.

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40

Thomas, Eileen. "Harsh labour 12 years on." Nursing Standard 8, no. 5 (October 20, 1993): 52–53. http://dx.doi.org/10.7748/ns.8.5.52.s64.

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41

Nuckton, Thomas J. "Medical Aspects of Harsh Environments." Wilderness & Environmental Medicine 15, no. 1 (March 2004): 67. http://dx.doi.org/10.1580/1080-6032(2004)015[0067:br]2.0.co;2.

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42

Dickinson, Robert. "The harsh truth about terraforming." Physics Today 74, no. 12 (December 1, 2021): 10. http://dx.doi.org/10.1063/pt.3.4891.

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43

Velderrain, Michelle, and Matthew Lindberg. "Modifiable Silicones for Harsh Environments." International Symposium on Microelectronics 2011, no. 1 (January 1, 2011): 000090–98. http://dx.doi.org/10.4071/isom-2011-ta3-paper3.

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Silicones have been used for decades in aerospace and other harsh environments where temperature extremes are common. As the level of sophistication increases for electronic devices to serve these industries where failure is not an option, the material supplier has to also be able to meet these needs. Silicones are polymeric materials composed primarily of repeating silicon and oxygen bonds, known as siloxanes, which can be optimized for various chemical and physical properties by incorporating different organic groups onto the silicon atom. Employing advanced processing techniques to the siloxane system can also greatly reduce mobile siloxane molecules to reduce contamination that can cause electronic failures during assembly or operation. Siloxane based polymeric systems are also unique polymers compared to standard organic based materials in that they have a large free volume that imparts a low modulus which absorbs stresses during thermal cycling as well as not degrading at continuous operating temperatures up to 250 C. They are also slightly polar which allows the incorporation of fillers to impart a variety of unique properties. Filler technology is also a rapidly growing enterprise where fillers with various particle sizes and shapes can be added to silicones to impart key properties such as maintaining electric conductivity at elevated temperatures. This paper will explain fundamentals of silicone chemistry and processing related to getting the optimal performance in harsh environments. A case study comparing two different electrically conductive fillers and how they can influence the electrical conductivity at elevated temperatures will be presented.
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44

Bybee, Karen. "Pipelines in a Harsh Environment." Journal of Petroleum Technology 56, no. 12 (December 1, 2004): 43–44. http://dx.doi.org/10.2118/1204-0043-jpt.

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Rodríguez, José. "NP-harsh problems in education." International Journal of Mathematical Education in Science and Technology 34, no. 4 (January 2003): 537–47. http://dx.doi.org/10.1080/0020739031000108547.

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46

Eriksen, Gert F., and Karsten Dyrbye. "Protective coatings in harsh environments." Journal of Micromechanics and Microengineering 6, no. 1 (March 1, 1996): 55–57. http://dx.doi.org/10.1088/0960-1317/6/1/011.

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47

Reinero, Bryan. "Harsh Sinha on Product Management." IEEE Software 35, no. 2 (March 2018): 105–8. http://dx.doi.org/10.1109/ms.2018.1661314.

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48

Wadman, Meredith. "Harsh spotlight falls on Vytorin." Nature Medicine 14, no. 5 (May 2008): 471. http://dx.doi.org/10.1038/nm0508-471c.

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49

Isaacs, Lawrence, and David J. Karras. "The Harsh Reality of Bioterrorism." Emergency Medicine News 23, no. 11 (November 2001): 8. http://dx.doi.org/10.1097/01.eem.0000288685.77477.0a.

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Kurlan, Matt. "Harsh Realities and Intelligent Policies." Emergency Medicine News 24, no. 4 (April 2002): 47. http://dx.doi.org/10.1097/01.eem.0000334189.04749.9b.

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