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1

Vondermans, Christel. "Smakelijk eten, hap hap! Hap." Kinderopvang 26, no. 6 (June 2016): 8–10. http://dx.doi.org/10.1007/s41189-016-0097-z.

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2

Lin, Ying-Dar Jason, Tzu-Chieh Tsai, San-Chiao Huang, and Mario Gerla. "HAP." ACM SIGCOMM Computer Communication Review 23, no. 4 (October 1993): 212–23. http://dx.doi.org/10.1145/167954.166258.

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3

MoolEnBURGH, DAnIël. "HAP." Mednet 5, no. 7 (July 2012): 15. http://dx.doi.org/10.1007/s12462-012-0192-z.

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4

Bennington, Geoffrey. "Hap." Oxford Literary Review 36, no. 2 (December 2014): 170–74. http://dx.doi.org/10.3366/olr.2014.0103.

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5

Wei, Wei, Dejun Jiang, Jin Xiong, and Mingyu Chen. "HAP." ACM Transactions on Architecture and Code Optimization 14, no. 3 (September 6, 2017): 1–25. http://dx.doi.org/10.1145/3106340.

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6

Tunçay, Ekin Ö., T. Tolga Demirtaş, and Menemşe Gümüşderelioğlu. "Microwave-induced production of boron-doped HAp (B-HAp) and B-HAp coated composite scaffolds." Journal of Trace Elements in Medicine and Biology 40 (March 2017): 72–81. http://dx.doi.org/10.1016/j.jtemb.2016.12.005.

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7

Bohn Stafleu van Loghum. "Hap, slik, foetsie." TvV Tijdschrift voor Verzorgenden 49, no. 11 (November 2017): 32–33. http://dx.doi.org/10.1007/s41183-017-0518-3.

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8

Andriessen, Peter, Leonie Bijland, and Dianne Jaspers. "De digitale HAP." Huisarts en wetenschap 63, no. 12 (November 30, 2020): 79. http://dx.doi.org/10.1007/s12445-020-0927-8.

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9

Veljović, Dj, I. Zalite, E. Palcevskis, I. Smiciklas, R. Petrović, and Dj Janaćković. "Microwave sintering of fine grained HAP and HAP/TCP bioceramics." Ceramics International 36, no. 2 (March 2010): 595–603. http://dx.doi.org/10.1016/j.ceramint.2009.09.038.

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10

Shikha, Deep, Monica Kumari, Anuradha Mohanty, Ashwini Kumar Singh, and Sanjay Kumar Sinha. "Microstructure and improvement in corrosion resistance of HAP and PVA/HAP." Journal of Polymer Engineering 42, no. 1 (November 22, 2021): 27–34. http://dx.doi.org/10.1515/polyeng-2021-0214.

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Abstract Polyvinyl alcohol (PVA) mixed with hydroxyapatite (HAP) has great potential for application as biomaterial. PVA/HAP powder was synthesized by sol–gel technique and was compressed to make pellets. These samples were examined with Fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscope (FESEM), atomic force microscope (AFM), X-ray diffraction (XRD) and electrochemical analysis (ECA) techniques. Compound formation of HAP and PVA were studied using XRD and microstructure was investigated by FESEM and AFM. Characteristics properties of the HAP and PVA/HAP composite are compared. Corrosion resistance of PVA/HAP in Ringer solution is better than HAP. Interesting microstructure features are correlated with the corrosion resistance. As the corrosion resistance is related with biocompatibility, the present work can be useful for the hard tissue implant.
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11

Khanra, Asit Kumar, Hwa Chul Jung, Kug Sun Hong, and Kwang Seon Shin. "Comparative property study on extruded Mg–HAP and ZM61–HAP composites." Materials Science and Engineering: A 527, no. 23 (September 2010): 6283–88. http://dx.doi.org/10.1016/j.msea.2010.06.031.

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12

Rapacz-Kmita, A., A. Ślósarczyk, Z. Paszkiewicz, and D. Paluch. "Evaluation of HAp-ZrO2composites and monophase HAp bioceramics. In vitro study." Journal of Materials Science 39, no. 18 (September 2004): 5865–67. http://dx.doi.org/10.1023/b:jmsc.0000040104.64482.4a.

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13

Kim, Hyehyun, Sudip Mondal, Bian Jang, Panchanathan Manivasagan, Madhappan Santha Moorthy, and Junghwan Oh. "Biomimetic synthesis of metal–hydroxyapatite (Au-HAp, Ag-HAp, Au-Ag-HAp): Structural analysis, spectroscopic characterization and biomedical application." Ceramics International 44, no. 16 (November 2018): 20490–500. http://dx.doi.org/10.1016/j.ceramint.2018.08.045.

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14

Kaur, Sarbjit, Niraj Bala, and Charu Khosla. "Investigations of thermal sprayed HAP and HAP-TiO2 composite coatings for biomedical applications." Anti-Corrosion Methods and Materials 66, no. 1 (January 7, 2019): 74–87. http://dx.doi.org/10.1108/acmm-03-2018-1917.

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Purpose The biomaterials are natural or synthetic materials used to improve quality of life either by replacing tissue/organ or assisting their function in medical field. The purpose of the study is to analyze the hydroxyapatite (HAP), HAP-TiO2 (25 percent) composite coatings deposited on 316 LSS by High Velocity Flame Spray (HVFS) technique. Design/methodology/approach The coatings exhibit almost uniform and dense microstructure with porosity (HAP = 0.153 and HAP-TiO2 composite = 0.138). Electrochemical corrosion testing was done on the uncoated and coated specimens in Ringer solution (SBF). As-sprayed coatings were characterized by XRD, SEM/EDS and cross-sectional X-ray mapping techniques before and after dipping in Ringer solution. Microhardness of composite coating (568.8 MPa) was found to be higher than HAP coating (353 MPa). Findings During investigations, it was observed that the corrosion resistance of steel was found to have increased after the deposition of HAP and HAP-TiO2 composite coatings. Thus, coatings serve as an effective diffusion barrier to prohibit the diffusion of ions from the SBF into the substrate. Composite coatings have been found to be more corrosion resistant as compared to HAP coating in the simulated body fluid. Research limitations/implications It has been concluded that corrosion resistance of HAP as well as composite coating is because of the desirable microstructural changes such as low porosity high microhardness and flat splat structures in coatings as compared to bare specimen. Practical implications This study is useful in the selection of biomedical implants. Social implications This study is useful in the field of biomaterials. Originality/value No reported literature on corrosion behavior of HAP+ 25%- TiO2 has been noted till now using flame spray technique. The main focus of the study is to investigate the HAP as well as composite coatings for biomedical applications.
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15

Loanapakul, Teerawat, Yuichi Otsuka, and Yoshiharu Mutoh. "Fatigue and Acoustic Emission Behavior of Plasma Sprayed HAp Top Coat and HAp/Ti Bond Coat with HAp Top Coat on Commercially Pure Titanium." Key Engineering Materials 452-453 (November 2010): 857–60. http://dx.doi.org/10.4028/www.scientific.net/kem.452-453.857.

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In the conventional hydroxyapatite (HAp) coating, the surface of commercially pure titanium (Cp-Ti) is blasted with Al2O3 grid-blasting powders and then plasma-sprayed with HAp. To improve the adhesive strength of HAp coating, the grid-blasting with Al2O3 powders and subsequently wet-blasting by HAp/Ti mixed powders were applied on Cp-Ti substrate at ambient temperature. On the wet-blasted surface of Cp-Ti, two-layers of coating composed of HAp/Ti bond coat and HAp top coat were deposited by plasma spraying. Both types of HAp-coated specimen could survive up to 107 cycles without spallation of HAp coating at the stress amplitude of 120 MPa under four point bending fatigue test. In order to clarify mechanical failure behavior of the coatings and Ti substrate, acoustic emission (AE) signals during the entire fatigue process were observed. Relationship between AE behavior and cracking process of coated specimen was evaluated. HAp top coat with HAp/Ti bond coat strongly improved the adhesive and cohesive strength, where dense AE signals occurred at the early stage of fatigue test corresponded to plastic deformation of Ti substrate and micro-cracks in coated layers. AE signals occurred at the final stage corresponded to crack propagation in coated specimen and spallations of coated layers.
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16

D., Y. M. "HAP : un nouveau traitement." Option/Bio 26, no. 534-535 (November 2015): 9. http://dx.doi.org/10.1016/s0992-5945(15)30341-x.

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17

Joseph, Ron. "What is HAP-Free?" Metal Finishing 97, no. 9 (September 1999): 94–97. http://dx.doi.org/10.1016/s0026-0576(01)80432-3.

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18

Cianca, E., R. Prasad, M. De Sanctis, A. De Luise, M. Antonini, D. Teotino, and M. Ruggieri. "Integrated satellite-HAP systems." IEEE Communications Magazine 43, no. 12 (December 2005): supl.33—supl.39. http://dx.doi.org/10.1109/mcom.2005.1561921.

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19

Ruppel, Helmut, and Ingrid Schmidt. "HAP Grieshaber: Elias (1957)." Zeitschrift für Pädagogik und Theologie 52, no. 1 (March 1, 2000): 101–2. http://dx.doi.org/10.1515/zpt-2000-520114.

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20

Burnham, Jason P., and Marin H. Kollef. "CAP, HCAP, HAP, VAP." Chest 152, no. 5 (November 2017): 909–10. http://dx.doi.org/10.1016/j.chest.2017.05.002.

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21

Kaur, Sarbjit, Niraj Bala, and Charu Khosla. "Characterization of Thermal-Sprayed HAP and HAP/TiO2 Coatings for Biomedical Applications." Journal of Thermal Spray Technology 27, no. 8 (October 15, 2018): 1356–70. http://dx.doi.org/10.1007/s11666-018-0766-3.

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22

Vignari, Michelle. "Non-ventilator health care-associated pneumonia (NV-HAP): NV-HAP Risk Factors." American Journal of Infection Control 48, no. 5 (May 2020): A10—A13. http://dx.doi.org/10.1016/j.ajic.2020.03.010.

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23

Toptan, Fatih, Alexandra C. Alves, Margarida A. Ferreira, Catarina I. da Silva Oliveira, and Ana M. P. Pinto. "Effect of HAP decomposition on the corrosion behavior of Ti-HAP biocomposites." Materials and Corrosion 69, no. 9 (February 27, 2018): 1292–99. http://dx.doi.org/10.1002/maco.201810049.

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24

Li, Shufeng, David Grace, Jibo Wei, and Dongtang Ma. "Inter-HAP handoff analysis for multi-cell short-endurance HAP communications systems." International Journal of Satellite Communications and Networking 29, no. 4 (December 3, 2010): 367–81. http://dx.doi.org/10.1002/sat.988.

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25

Zhang, Zhibin, Xianhui Shi, Yanhao Zhang, Shengrui Wang, Meng Wang, Yuchen Wang, W. M. Sumana Bandara Weerakoon, and Olga Sanginova. "Study on immobilization of diatomite, Ca(H2PO4)2, CaCO3, HAP and nano-HAP for heavy metal contaminated sediment." Water Quality Research Journal 55, no. 4 (October 21, 2020): 370–81. http://dx.doi.org/10.2166/wqrj.2020.117.

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Abstract The immobilization performances of Diatomite, Ca(H2PO4)2, CaCO3, Hydroxyapatite (HAP) and Nano-HAP (n-HAP) for Zn, Mn, Pb, and Cd contaminated sediments were investigated by immobilization experiments and evaluated by the European Community Bureau of Reference (BCR) extraction test, toxicity characteristic leaching procedure (TCLP). The result of BCR indicated that HAP and Nano-HAP (n-HAP) had a better immobilization effect on metal contaminated sediments, and the residual fractions of Zn, Mn, Pb, and Cd increased from 30.4, 31.9, 55.49 and 54.27% to 36, 39, 72, and 57%, respectively. The order for immobilized effects of additive was: n-HAP > HAP > CaCO3 > Ca(H2PO4)2 > diatomite. However, the cost-effectiveness of HAP was slightly higher than that of n-HAP, so HAP was more suitable for immobilization of heavy metals in sediment. The TCLP test showed that with HAP as immobilization the leaching amount was reduced by approximately 76, 28, 78, and 85% for Zn, Mn, Pb, and Cd, respectively, compared to the blank group. The results also proved that HAP would be an effective and economical agent for immobilizing heavy metals in sediment, with the optimum mass dosage of 10% (the mass ratios of HAP/sediment (dry weight)) of the sediment.
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26

Shuai, Cijun, Li Yu, Wenjing Yang, Shuping Peng, Yancheng Zhong, and Pei Feng. "Phosphonic Acid Coupling Agent Modification of HAP Nanoparticles: Interfacial Effects in PLLA/HAP Bone Scaffold." Polymers 12, no. 1 (January 13, 2020): 199. http://dx.doi.org/10.3390/polym12010199.

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In order to improve the interfacial bonding between hydroxyapatite (HAP) and poly-l-lactic acid (PLLA), 2-Carboxyethylphosphonic acid (CEPA), a phosphonic acid coupling agent, was introduced to modify HAP nanoparticles. After this. the PLLA scaffold containing CEPA-modified HAP (C-HAP) was fabricated by selective laser sintering (frittage). The specific mechanism of interfacial bonding was that the PO32− of CEPA formed an electrovalent bond with the Ca2+ of HAP on one hand, and on the other hand, the –COOH of CEPA formed an ester bond with the –OH of PLLA via an esterification reaction. The results showed that C-HAP was homogeneously dispersed in the PLLA matrix and that it exhibited interconnected morphology pulled out from the PLLA matrix due to the enhanced interfacial bonding. As a result, the tensile strength and modulus of the scaffold with 20% C-HAP increased by 1.40 and 2.79 times compared to that of the scaffold with HAP, respectively. In addition, the scaffold could attract Ca2+ in simulated body fluid (SBF) solution by the phosphonic acid group to induce apatite layer formation and also release Ca2+ and PO43− by degradation to facilitate cell attachment, growth and proliferation.
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27

Syarif, Dani, Djoko Prajitno, Ahmad Kurniawan, Muhamad Febrian, and Ronny Lesmana. "Hydrothermally synthesis and characterization of HAp and Zr-doped HAp nanoparticles from bovine bone and zircon for photodynamic therapy." Processing and Application of Ceramics 15, no. 2 (2021): 146–53. http://dx.doi.org/10.2298/pac2102146s.

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HAp and Zr-doped HAp nanoparticles were synthesized from bovine bone and local zircon material by using the hydrothermal method. XRD analysis showed that the HAp and Zr-doped HAp nanoparticles had hexagonal structure with a crystallite size of 20-36 nm and the lattice constants a = 9.8-9.9? and c = 6.5-6.8 ?. XRD data also showed that up to 20 at.% of Zr can be accommodated in HAp crystal structure. The lattice constant and cell volume decreased with increasing Zr concentration. FTIR data confirmed that the majority of functional groups that exist on the surface of the HAp and Zr-doped HAp nanoparticles were the hydroxyl and phosphate groups. Suspensions with the HAp and Zr-doped HAp nanoparticles prepared using citric acid as dispersant were stable with zeta potential between ?31 and ?35mV at pH = 7. Reactive oxygen species are generated on the produced HAp and Zr-doped Hap nanoparticles and confirm their potential for application in photodynamic therapy.
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28

Pratiwi, Lia, Yosi Maria Wijaya, and Monica Saptiningsih. "Expository Methods of Bundles HAP Affected the Implementation of HAP Prevention of Adult Inpatient Unit." Jurnal Ners dan Kebidanan (Journal of Ners and Midwifery) 9, no. 3 (December 28, 2022): 401–6. http://dx.doi.org/10.26699/jnk.v9i3.art.p401-406.

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Hospital-acquired pneumonia (HAP) incidents in private hospitals in Bandung reached 0.11 % -1.03 %. HAP affects the quality of hospital services related to patient safety. One of the methods used for socializing implementation of HAP prevention was the expository method means learning method that is directly implemented to maintain contact between the speaker and audience. The purpose of this study was to determine the effect of the expository method of education on HAP bundles on the implementation of HAP prevention in the adult inpatient units. The study was designed by pre-experimental design one group pretest-posttest. A total of 16 associate nurses were part of the research using the purposive sampling technique in the adult inpatient units. The variable in the study was the implementation of HAP prevention which was measured by using an observation sheet. Wilcoxon tests were used to compare the scores between pretest-posttest. The researched result was P-value 0.000 (P-value < α 0.05), meaning the expository method of education on HAP bundle affected the implementation of HAP prevention in the adult inpatient unit. Suggestions derived from this study are to advise the infection prevention and control committee to implement the expository method in socializing bundles to prevent infections categorized as HAIs to health workers and to perform a regular evaluation.
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29

Furuseki, Tomoki, and Yasumitsu Matsuo. "Anhydrous Proton Conductivity in HAp-Collagen Composite." Journal of Composites Science 6, no. 8 (August 10, 2022): 236. http://dx.doi.org/10.3390/jcs6080236.

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It is well known that a proton conductor is needed as an electrolyte of hydrogen fuel cells, which are attracting attention as an environmentally friendly next-generation device. In particular, anhydrous proton-conducting electrolytes are highly desired because of their advantages, such as high catalytic efficiency and the ability to operate at high temperatures, which will lead to the further development of fuel cells. In this study, we have investigated the proton-conducting properties of the hydroxyapatite (HAp)-collagen composite without external humidification conditions. It was found that, by injecting HAp into collagen, the electrical conductivity becomes higher than that of the HAp or the collagen. Moreover, the motional narrowing of the proton NMR line is observed above 130 °C. These results indicate that the electrical conductivity observed in the HAp-collagen composite is caused by mobile protons. Furthermore, we measured the proton conduction of HAp-collagen composite films with different HAp contents and investigated the necessity of the appearance of proton conductivity in HAp-collagen composites. HAp content (n = 0–0.38) is the number of HAp per collagen peptide representing Gly-Pro-Hyp. These results indicate that injection of HAp into collagen decreases the activation energy of proton conduction which becomes almost constant above a HAp content n of 0.3. It is deduced that the proton-conduction pathway in the HAp-collagen composite is fully formed above n = 0.3. Furthermore, these results indicate that the value of the activation energy of proton conductivity was lowered, accompanied by the formation of the HAp-collagen composite, and saturated at n > 0.3. From these results, the HAp-collagen composite forms the proton-conduction pathway n > 0.3 and becomes the proton conductor with no external humidification in the condition of n > 0.3 above 130 °C.
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30

Gultom, Amry Daulat, and Diah Yuniarti. "Kajian Teknologi High Altitude Platform (HAP) [Study of High Altitude Platform (HAP) Technology]." Buletin Pos dan Telekomunikasi 14, no. 1 (July 29, 2016): 11. http://dx.doi.org/10.17933/bpostel.2016.140102.

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31

Zhou, Yuan-Yuan, Song Li, Da-Lu Wang, Xi Han, and Xiaolin Lei. "Fabrication of Collagen/HAP Electrospun Scaffolds with Perfect HAP Nanorods Along Nanofiber Orientation." Science of Advanced Materials 10, no. 7 (July 1, 2018): 930–36. http://dx.doi.org/10.1166/sam.2018.3278.

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32

Wang, Youfa, Tianjian Liu, Yuhua Yan, and Shipu Li. "Comparative study on lattice parameters of HAP nanoparticles with those of HAP whiskers." Journal of Wuhan University of Technology-Mater. Sci. Ed. 23, no. 3 (June 2008): 395–98. http://dx.doi.org/10.1007/s11595-007-3395-0.

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33

Mani Rahulan, K., G. Vinitha, S. Ganesan, Reji Philip, and P. Aruna. "Synthesis and optical limiting studies of HAP and HAP@SiO2 core–shell nanoparticles." Journal of Materials Science: Materials in Electronics 23, no. 4 (September 11, 2011): 877–81. http://dx.doi.org/10.1007/s10854-011-0510-y.

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34

Ding Xifeng, 丁西峰, 马. 赛. Ma Sai, 赵尚弘 Zhao Shanghong, 王. 翔. Wang Xiang, 郑永兴 Zheng Yongxing, 温. 泉. Wen Quan, and 林. 涛. Lin Tao. "BER performance and link model of HAP-GEO-HAP all-optical amplify-and-forward relaying." Infrared and Laser Engineering 46, no. 6 (2017): 622003. http://dx.doi.org/10.3788/irla201746.0622003.

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35

Chiengsorn, Rawisada, Supimkarn Lioroongcharoen, Adisri Charoenpanich, and Tawat Chanadee. "Comparison of properties of HAp and CaTiO3-HAp ceramic composite fabricated by different sintering conditions." Science of Sintering, no. 00 (2024): 19. http://dx.doi.org/10.2298/sos240321019c.

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A hydroxyapatite (HAp) ceramic and a 20% wt CaTiO3-HAp ceramic composite for potential application as biomaterials were produced using single-step sintering (SS) and two-step sintering (TSS) in air. The sample pellets were SS sintered at 1250 ?C with a holding time of 1 h. For TSS, the pellets were heated at 10?C/min to 1250?C (T1) and held at this temperature for 20 min (t1). The temperature was then rapidly lowered at 20?C/min to 1150?C (T2), and held at this temperature for 10 min (t2). The 20% wt CaTiO3-HAp ceramic composite obtained from TSS had a fine grain of 0.56 ? 0.04 mm due to the restraint of grain growth caused by the fast cooling from T1 to T2 and the hard CaTiO3 particles dispersed in the HAp matrix. The microstructure refinement of the 20% wt CaTiO3-HAp ceramic composite fabricated by TSS produced suitable sintered density due to increased locking at triple junctions. This ceramic composite exhibited fracture toughness of 2.10 MPa.m1/2 with a brittleness of 1.97 mm-1/2, indicating that crack propagation was suppressed. MG-63 osteoblast cells were able to adhere to the surface of both HAp and the 20% wt CaTiO3-HAp ceramic composite produced by TSS and were no different between 3 and 7 days of culture. The alkaline phosphatase activity of MG-63 cells was higher on both ceramics cultured in osteogenic differentiation medium than in complete growth medium, which indicated more efficient osteoinductivity.
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Pawarangkool, Kanyakorn, and Wirunya Keawwattana. "Study the Effect of the Addition of HAp from Crocodile Bones on the Mechanical Properties of PLA/HAp Composites." Advanced Materials Research 834-836 (October 2013): 237–40. http://dx.doi.org/10.4028/www.scientific.net/amr.834-836.237.

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In this work, hydroxyapatite (HAp) was produced from crocodile bones by thermal process at 900°C. X-ray diffractometer (XRD), Fourier transform infrared spectrometer (FTIR) and Scanning electron microscope (SEM) were used to characterize the obtained HAp. Polylactic acid (PLA)/HAp composites were prepared by melt blending as follows: 95/5, 90/10 and 85/15 (weight ratio). The effect of the amount of HAp on the mechanical properties including tensile strength, modulus, elongation at break and impact strength of PLA/HAp composites was undertaken. It was found that tensile strength and elongation at break of the composites decreased with an increase of HAp content, while modulus and impact strength showed no significant effect.
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37

Wang, Guo Qing, and Li Ping Niu. "HAP/UHMWPE-Coated Titanium Preparation of Biological Materials." Advanced Materials Research 391-392 (December 2011): 625–28. http://dx.doi.org/10.4028/www.scientific.net/amr.391-392.625.

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Hydroxyapatite (HAP) is known as a kind of bioactive and biocompatible material, HAP coatings are used to improve the biocompatibility of substrate by some researchers. In this paper, homogenous precipitation of hydroxyapatite was formed in the system of CaNa2EDTA -(NH4)2HPO4-NH4OH-H2O, and HAP powder was obtained after calcinations at 800 and grinding. Add HAP in UHMWPE o-xylene solution to get dipping solution and prepare HAP/UHMWPE-coated titanium by dipping coating process. Scratch test demonstrated that Ti-HAP/UHMWPE material started to shine metallic luster under 1.03 N, and adhesive strength is 32MPa. UHMWPE not only simplified the process of preparing HAP-coated material, but also enhanced the adhesive strength, which shows great potential in biomedical areas.
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38

Wicky, Paul-Henri, Ignacio Martin-Loeches, and Jean-François Timsit. "HAP and VAP after Guidelines." Seminars in Respiratory and Critical Care Medicine 43, no. 02 (January 18, 2022): 248–54. http://dx.doi.org/10.1055/s-0041-1740246.

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AbstractNosocomial pneumonia is associated with worsened prognosis when diagnosed in intensive care unit (ICU), ranging from 12 to 48% mortality. The incidence rate of ventilation-acquired pneumonia tends to decrease below 15/1,000 intubation-day. Still, international guidelines are heterogeneous about diagnostic criteria because of inaccuracy of available methods. New entities have thus emerged concerning lower respiratory tract infection, namely ventilation-acquired tracheobronchitis (VAT), or ICU-acquired pneumonia (ICUAP), eventually requiring invasive ventilation (v-ICUAP), according to the type of ventilation support. The potential discrepancy with non-invasive methods could finally lead to underdiagnosis in almost two-thirds of non-intubated patients. Delayed diagnostic could explain in part the 2-fold increase in mortality of penumonia when invasive ventilation is initiated. Here we discuss the rationale underlying this new classification.Many situations can lead to misdiagnosis, even more when the invasive mechanical ventilation is initiated. The chest radiography lacks sntivity and specificity for diagnosing pneumonia. The place of chest computed tomography and lung ultrasonography for routine diagnostic of new plumonary infiltrate remain to be evaluated.Microbiological methods used to confirm the diagnostic can be heterogeneous. The development of molecular diagnostic tools may improve the adequacy of antimicrobial therapies of ventilated patients with pneumonia, but we need to further assess its impact in non-ventilated pneumonia.In this review we introduce distinction between hospital-acquired pneumonia according to the localization in the hospital and the oxygenation/ventilation mode. A clarification of definition is the first step to develop more accurate diagnostic strategies and to improve the patients' prognosis.
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39

P, Hystad, Shupler M, Gustafson P, and Brauer M. "The PURE-Air HAP Study." Environmental Epidemiology 3 (October 2019): 173. http://dx.doi.org/10.1097/01.ee9.0000607692.54585.95.

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40

Lung, Mayli, and Gema Codina. "Molecular diagnosis in HAP/VAP." Current Opinion in Critical Care 18, no. 5 (October 2012): 487–94. http://dx.doi.org/10.1097/mcc.0b013e3283577d37.

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41

Broekhuizen, Lidewij. "Adequate antibioticavoorschriften op de HAP." Huisarts en wetenschap 60, no. 7 (July 2017): 318. http://dx.doi.org/10.1007/s12445-017-0197-2.

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42

Fine, Lynn S. "Non-ventilator health care-associated pneumonia (NV-HAP): Pathogenesis and microbiology of NV-HAP." American Journal of Infection Control 48, no. 5 (May 2020): A7—A9. http://dx.doi.org/10.1016/j.ajic.2020.03.009.

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43

Rao, R. Ramachandra, H. N. Roopa, and T. S. Kannan. "Synthesis of Pure HAP and HAP-β-TCP Biphasic Mixtures by Solid State Reaction." Transactions of the Indian Ceramic Society 57, no. 3 (January 1998): 73–76. http://dx.doi.org/10.1080/0371750x.1998.10804835.

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44

Luo, Liang Liang, Liang Hu, Xiao Feng Xing, Wei Min Gao, and Yu Ping Guo. "Preparation of β-CD-HAP Composite Microspheres." Key Engineering Materials 697 (July 2016): 67–70. http://dx.doi.org/10.4028/www.scientific.net/kem.697.67.

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β-cyclodextin-hydroxyapatite (β-CD-HAP) composite microspheres were prepared in invert microemulsion method using spherical morphology hydroxyapatite nanoparticles (nHAP) as raw materials, Span-Tween cosurfactant as mixed emulsifier and epichlorohydrin as cross linker agent. The structure, morphology and β-CD-HAP was characterized by Fourier transform Infrared spectroscope (FT-IR), X-ray powder diffraction (XRD), transmission electron microscope (SEM). Results showed that the β-CD-HAP microspheres were synthesized by adding epichlorohydrin, span-80, tween-80, and sodium hydroxide and the particle size of β-CD-HAP composite microsphere with good dispersion was several tens of nanometer.
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45

Gintu, Agung Rimayanto, Elizabeth Betty Elok Kristian, and Yohanes Martono. "Karakterisasi Pasta Gigi Berbahan Abrasif Hidroksiapatit (HAp)." Jurnal Kimia Riset 5, no. 2 (December 7, 2020): 120. http://dx.doi.org/10.20473/jkr.v5i2.22503.

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Tootpaste was a product for dental care to clean, beautify and replace the minerals decay from the dent surface. To prevent the damage of the mineral layers on the surface, added the remineralitation compounds in the formula of the toothpaste. The remineralitation agents commonly add was CaCO3 and CaPO4, during the technological development the calcium compounds added was calcium in nano size like Hydroxyapatite (HAp). In this study produced the contains abrasive HAp and CaCO3 with the mix ratio CaCO3, 50:50 (HAp:CaCO3) and HAp. The characterization to the toothpaste with CaCO3 abrasive showed the Calcium contains 21,10 ± 0,0577%; dispersibility 936,37 ± 39,42gcm/s; pH 8,3 ± 0,00; and viscosity 25 ± 0,00 P.a. The toothpaste with CaCO3:HAp (50:50) abrasive showed the Calcium contains 27,03 ± 0,0333%; dispersibility 931,93 ± 22,62gcm/s; pH 8,8 ± 0,00; and viscosity 27 ± 0,00 P.a. The toothpaste with HAp abrasive showed the Calcium contains 27,67 ± 0,0882%; dispersibility 987,33 ± 39,50gcm/s; pH 8,9 ± 0,00; and viscosity 27,5 ± 0,00 P.a. The contamination of microbiology did not found in all of the toothpastes along the storage. Based on the entire organoleptic test against the toothpastes, the formula of toothpaste with the mix of CaCO3:HAp was les liked.
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46

Purushotham, Thiyagarajan, Alagesan Thangavel, Shanmugharaj A.M., Padmapriya Arumugam, and Kalaivani Raman. "Thermal Degradation Process and Kinetics of Gelatin/HAP Composites." ECS Transactions 107, no. 1 (April 24, 2022): 16507–17. http://dx.doi.org/10.1149/10701.16507ecst.

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Hydroxyapatite (HAP)-loaded gelatin, a biopolymeric composite, has gained a lot of attention in biomedical applications like bone regeneration because it compensates for the low fracture stiffness and fragility of pure HAP. Furthermore, it improves bone injury tolerance by controlling the amorphous calcium phosphate deposition kinetics and microstructure. Doping metal ions in HAP and thereafter preparing gelatin/HAP composites may result in an increase in the desired property upgrades. Understanding the breakdown kinetics of gelatin/HAP composites offers the opportunity for the composites to be engineered for specific purposes. In the present work, gelatin/HAP composites with/without metal-ion doping were prepared and subjected to thermal degradation studies using thermogravimetric analysis under a nitrogen environment to understand their degradation kinetics.
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47

Krucińska, Izabella, Olga Chrzanowska, Maciej Boguń, Marek Kowalczuk, and Piotr Dobrzyński. "Fabrication of Plga/Hap and Plga/Phb/Hap Fibrous Nanocomposite Materials for Osseous Tissue Regeneration." Autex Research Journal 14, no. 2 (June 1, 2014): 95–110. http://dx.doi.org/10.2478/aut-2014-0006.

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Abstract The study presents the manufacturing of nanofibrous structures as osteoconductive, osteoinductive materials for osseous tissue regeneration. The fibrous structures were obtained by electrospinning of poly(l-lactide-coglicolide) (PLGA) with addition of hydroxyapatite (HAp) and of a blend of PLGA with polyhydroxybutyrate with HAp added. The polymers used in the experiment were synthesised by an innovative method with a zirconium catalyst. First, the optimal electrospinning process parameters were selected. For the characterisation of the obtained osseous tissue reconstruction materials, the physical, macroscopic, functional, mechanical and thermal properties as well as crystallinity index were studied. The study of the radiation sterilisation influence on average molar mass, thermal and mechanical properties was made in order to analyse the degradation effect.
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48

Davila, Shannon. "Non-ventilator health care-associated pneumonia (NV-HAP): Taking action to improve NV-HAP outcomes." American Journal of Infection Control 48, no. 5 (May 2020): A28—A35. http://dx.doi.org/10.1016/j.ajic.2020.03.004.

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49

Quinn, Barbara, Karen K. Giuliano, and Dian Baker. "Non-ventilator health care-associated pneumonia (NV-HAP): Best practices for prevention of NV-HAP." American Journal of Infection Control 48, no. 5 (May 2020): A23—A27. http://dx.doi.org/10.1016/j.ajic.2020.03.006.

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50

Renaud, Cherie, and Marin H. Kollef. "Classical and Molecular Techniques to Diagnose HAP/VAP." Seminars in Respiratory and Critical Care Medicine 43, no. 02 (January 18, 2022): 219–28. http://dx.doi.org/10.1055/s-0041-1739359.

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AbstractNosocomial pneumonia, including hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP), are the most common nosocomial infections occurring in critically ill patients requiring intensive care. However, challenges exist in making a timely and accurate diagnosis of HAP and VAP. Under diagnosis of HAP and VAP can result in greater mortality risk, especially if accompanied by delays in the administration of appropriate antimicrobial treatment. Over diagnosis of HAP and VAP results in the unnecessary administration of broad spectrum antibiotics that can lead to further escalation of antibiotic resistance. Optimal diagnosis and management of HAP and VAP require a systematic approach that combines clinical and radiographic assessments along with proper microbiologic techniques. The use of more invasive sampling methods (bronchoalveolar lavage and protected specimen brush) may enhance specimen collection resulting in more specific diagnoses to limit unnecessary antibiotic exposure. Molecular techniques, currently in use and investigational technique, may improve the diagnosis of HAP and VAP by allowing more rapid identification of offending pathogens, if present, thus increasing both appropriate antibiotic treatment and avoiding unnecessary drug exposure.
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