Log in

Relevant bibliographies by topics / Hamigeran

Contents

Journal articles
Dissertations / Theses
Book chapters

Academic literature on the topic 'Hamigeran'

Author: Grafiati

Published: 4 June 2021

Last updated: 6 September 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Hamigeran.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Hamigeran"

1

Taber, Douglass F., and Weiwei Tian. "Synthesis of (−)-Hamigeran B." Journal of Organic Chemistry 73, no. 19 (October 3, 2008): 7560–64. http://dx.doi.org/10.1021/jo8010683.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Clive, Derrick L. J., and Jian Wang. "Synthesis of natural (−)-hamigeran B." Tetrahedron Letters 44, no. 42 (October 2003): 7731–33. http://dx.doi.org/10.1016/j.tetlet.2003.08.089.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Clive, Derrick L. J., and Jian Wang. "Synthesis of (±)-Hamigeran B, (−)-Hamigeran B, and (±)-1-epi-Hamigeran B: Use of Bulky Silyl Groups to Protect a Benzylic Carbon−Oxygen Bond from Hydrogenolysis." Journal of Organic Chemistry 69, no. 8 (April 2004): 2773–84. http://dx.doi.org/10.1021/jo030347v.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Jiang, Biao, Ming-ming Li, Ping Xing, and Zuo-gang Huang. "A Concise Formal Synthesis of (−)-Hamigeran B." Organic Letters 15, no. 4 (February 4, 2013): 871–73. http://dx.doi.org/10.1021/ol400030a.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Mukherjee, Herschel, Nolan T. McDougal, Scott C. Virgil, and Brian M. Stoltz. "A Catalytic, Asymmetric Formal Synthesis of (+)-Hamigeran B." Organic Letters 13, no. 5 (March 4, 2011): 825–27. http://dx.doi.org/10.1021/ol102669z.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Trost, Barry M., Carole Pissot-Soldermann, and Irwin Chen. "A Short and Concise Asymmetric Synthesis of Hamigeran B." Chemistry - A European Journal 11, no. 3 (January 21, 2005): 951–59. http://dx.doi.org/10.1002/chem.200400558.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Li, Ruo-Xin, Rui Han, Guo-Jie Wu, Fu-She Han, and Jin-Ming Gao. "Synthesis and Biological Evaluation of Diversified Hamigeran B Analogs as Neuroinflammatory Inhibitors and Neurite Outgrowth Stimulators." Marine Drugs 18, no. 6 (June 11, 2020): 306. http://dx.doi.org/10.3390/md18060306.

Full text

Abstract:

We describe the efficient synthesis of a series of new simplified hamigeran B and 1-hydroxy-9-epi-hamigeran B norditerpenoid analogs (23 new members in all), structurally related to cyathane diterpenoid scaffold, and their anti-neuroinflammatory and neurite outgrowth-stimulating (neurotrophic) activity. Compounds 9a, 9h, 9o, and 9q exhibited moderate nerve growth factor (NGF)-mediated neurite-outgrowth promoting effects in PC-12 cells at the concentration of 20 μm. Compounds 9b, 9c, 9o, 9q, and 9t showed significant nitric oxide (NO) production inhibition in lipopolysaccharide (LPS)-activated BV-2 microglial cells, of which 9c and 9q were the most potent inhibitors, with IC50 values of 5.85 and 6.31 μm, respectively. Two derivatives 9q and 9o as bifunctional agents displayed good activities as NO production inhibitors and neurite outgrowth-inducers. Cytotoxicity experiments, H2O2-induced oxidative injury assay, and ELISA reaction speculated that compounds may inhibit the TNF-α pathway to achieve anti-inflammatory effects on nerve cells. Moreover, molecular docking studies provided a better understanding of the key structural features affecting the anti-neuroinflammatory activity and displayed significant binding interactions of some derivatives (like 9c, 9q) with the active site of iNOS protein. The structure-activity relationships (SARs) were also discussed. These results demonstrated that this structural class compounds offered an opportunity for the development of a new class of NO inhibitors and NGF-like promotors.

APA, Harvard, Vancouver, ISO, and other styles

8

Cao, Bao-Chen, Guo-Jie Wu, Fang Yu, Yu-Peng He, and Fu-She Han. "A Total Synthesis of (−)-Hamigeran B and (−)-4-Bromohamigeran B." Organic Letters 20, no. 12 (June 6, 2018): 3687–90. http://dx.doi.org/10.1021/acs.orglett.8b01490.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Jiang, Biao, Ming-ming Li, Ping Xing, and Zuo-gang Huang. "ChemInform Abstract: A Concise Formal Synthesis of (-)-Hamigeran B (XIV)." ChemInform 44, no. 28 (June 21, 2013): no. http://dx.doi.org/10.1002/chin.201328176.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Sperry, Jeffrey B., and Dennis L. Wright. "Synthesis of the hamigeran skeleton through an electro-oxidative coupling reaction." Tetrahedron Letters 46, no. 3 (January 2005): 411–14. http://dx.doi.org/10.1016/j.tetlet.2004.11.108.

Full text

APA, Harvard, Vancouver, ISO, and other styles

More sources

Dissertations / Theses on the topic "Hamigeran"

1

Tian, Weiwei. "Rhodium-mediated carbene insertion synthesis of (-)-hamigeran B and the (-)-sordaricin core /." Access to citation, abstract and download form provided by ProQuest Information and Learning Company; downloadable PDF file, 119 p, 2008. http://proquest.umi.com/pqdweb?did=1609287781&sid=2&Fmt=2&clientId=8331&RQT=309&VName=PQD.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Lundy, Sarah Diane. "Synthetic Approaches to the Bicyclic Core of TEO3.1, Hamigerone and Embellistatin." Thesis, University of Canterbury. Chemistry, 2007. http://hdl.handle.net/10092/3273.

Full text

Abstract:

This thesis describes synthetic studies directed towards the total synthesis of the natural products TEO3.1, hamigerone and embellistatin. Chapter One provides an overview, which details the role of antifungal natural products in the pharmaceutical and agrochemical industries, and describes the association between total synthesis and natural products. Three structurally related natural products TEO3.1, hamigerone and embellistatin are introduced as synthetic targets and a strategy for their synthesis is proposed involving an intramolecular Diels-Alder (IMDA) reaction, followed by addition-elimination chemistry. Investigations into the application of the IMDA reaction to the synthesis of the bicyclic core are described in Chapter Two. A Julia olefination reaction was used to install the diene moiety and allowed for the successful synthesis of a model triene precursor. The IMDA cyclisation of the triene was shown to proceed with high endo-selectivity. However, efforts to generate the diene-containing bicyclic core failed and, as a result, this approach to the natural products was abandoned. Chapter Three introduces the diene-regenerative Diels-Alder reaction as an alternative strategy for the direct installation of the diene moiety. The preparation of a model system is described, which established methodology for the efficient preparation of the pyrone-containing Diels-Alder substrate. Cyclisation of this material via a [4 + 2] cycloaddition reaction, followed by extrusion of carbon dioxide, proved a viable method for generating the desired cyclohexadiene system. In Chapter Four, the previously established methodology is applied to the synthesis of the fully functionalised bicyclic core of TEO3.1, hamigerone and embellistatin. The preparation of the racemic Diels-Alder substrate and its successful cyclisation to the bicyclic core is described. An investigation into the preparation of chiral material is also discussed, as well as the description of a model study for the installation of the various side-chains of the natural products. The chapter concludes with a brief discussion of the future studies required to complete the total synthesis of the TEO3.1, hamigerone and embellistatin.

APA, Harvard, Vancouver, ISO, and other styles

3

Murlidhar, Shinde Harish. "Enantioselective Total Synthesis Of Diverse, Bioactive Natural Products : (+)-1S-Minwanenone, (+)-SCH 642305 And 6-EPI-(-)-Hamigeran B." Thesis, 2007. https://etd.iisc.ac.in/handle/2005/590.

Full text

Abstract:

Natural product synthesis is one of the most creative branch of chemistry in terms of its boundless scope for innovation and has stimulated several generations of synthetic organic chemists. With advancement in the technology, particularly in the isolation and purification techniques, high-field NMR and X-ray crystallography, it has become fairly routine to isolate and assign the structures, high-field NMR and X-ray crystallography, it has become fairly routine to isolate and assign the structures, even to those complex molecules, which are available only in microscopic quantities from natural sources. Concurrently, one has witnessed tremendous advances in the availability of new synthetic methodologies with high region-, stereo-, and enantiocontrol for one or multiple C-C bond formations and rapid generation of molecular complexity. These developments have rekindled interest with total synthesis of natural products as platforms for testing and validating new reactions and strategies. Many natural products exhibit wide range of biological activities and thus provide good leads in drug discovery but quite often such bioactive compounds are obtained only in minute quantities from Nature. Hence, there is need to synthesize them to obtain requisite quantities and build diversity around their scaffold to further explore their therapeutic potential. Thus, natural product synthesis combines both intellectual challenge and possible application for human wellbeing. Our research group is actively engaged in the synthesis of structurally complex, bioactive natural products and as a part of this endeavour, total syntheses of several bioactive compounds have been accomplished in our laboratory in recent past. The present thesis has also evolved around the ongoing theme directed towards natural product synthesis and is organized under three chapters. Chapter I: Total synthesis of (+)-1S-Minwanenone Chapter II: Enantioselective total synthesis of the bioactive natural product (+)-Sch 642305. Chapter III: Enantiospecific total synthesis of 6-epi-(-)-Hamigeran B.

APA, Harvard, Vancouver, ISO, and other styles

4

Murlidhar, Shinde Harish. "Enantioselective Total Synthesis Of Diverse, Bioactive Natural Products : (+)-1S-Minwanenone, (+)-SCH 642305 And 6-EPI-(-)-Hamigeran B." Thesis, 2007. http://hdl.handle.net/2005/590.

Full text

Abstract:

Natural product synthesis is one of the most creative branch of chemistry in terms of its boundless scope for innovation and has stimulated several generations of synthetic organic chemists. With advancement in the technology, particularly in the isolation and purification techniques, high-field NMR and X-ray crystallography, it has become fairly routine to isolate and assign the structures, high-field NMR and X-ray crystallography, it has become fairly routine to isolate and assign the structures, even to those complex molecules, which are available only in microscopic quantities from natural sources. Concurrently, one has witnessed tremendous advances in the availability of new synthetic methodologies with high region-, stereo-, and enantiocontrol for one or multiple C-C bond formations and rapid generation of molecular complexity. These developments have rekindled interest with total synthesis of natural products as platforms for testing and validating new reactions and strategies. Many natural products exhibit wide range of biological activities and thus provide good leads in drug discovery but quite often such bioactive compounds are obtained only in minute quantities from Nature. Hence, there is need to synthesize them to obtain requisite quantities and build diversity around their scaffold to further explore their therapeutic potential. Thus, natural product synthesis combines both intellectual challenge and possible application for human wellbeing. Our research group is actively engaged in the synthesis of structurally complex, bioactive natural products and as a part of this endeavour, total syntheses of several bioactive compounds have been accomplished in our laboratory in recent past. The present thesis has also evolved around the ongoing theme directed towards natural product synthesis and is organized under three chapters. Chapter I: Total synthesis of (+)-1S-Minwanenone Chapter II: Enantioselective total synthesis of the bioactive natural product (+)-Sch 642305. Chapter III: Enantiospecific total synthesis of 6-epi-(-)-Hamigeran B.

APA, Harvard, Vancouver, ISO, and other styles

Book chapters on the topic "Hamigeran"

1

"Synthesis of (-)-Hamigeran B." In Organic Synthesis, 120–21. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2006. http://dx.doi.org/10.1002/0470056312.ch61.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Miesch, Michel, Tania Welsch, Vincent Rietsch, and Laurence Miesch. "Total Syntheses of Hamigeran B." In Strategies and Tactics in Organic Synthesis, 203–29. Elsevier, 2013. http://dx.doi.org/10.1016/b978-0-08-099362-1.00007-2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Taber, Douglass. "Transition Metal Catalyzed Construction of Carbocyclic Rings: (-)-Hamigeran B." In Organic Synthesis. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780199764549.003.0076.

Full text

Abstract:

Several elegant methods for the enantioselective transformation of preformed prochiral rings have been put forward. Derek R. Boyd of Queen’s University, Belfast devised (Chem. Commun. 2008, 5535) a Cu catalyst that effected allylic oxidation of cyclic alkenes such as 1 with high ee. Christoph Jaekel of the Ruprecht-Karls-Universität Heidelberg established (Adv. Synth. Cat. 2008, 350, 2708) conditions for the enantioselective hydrogenation of cyclic enones such as 3. Marc L. Snapper of Boston College developed (Angew. Chem. Int. Ed. 2008, 47, 5049) a Cu catalyst for the enantioselective allylation of activated cyclic enones such as 5. Alexandre Alexakis of the University of Geneva showed (Angew. Chem. Int. Ed. 2008, 47, 9122) that dienones such as 8 could be induced to undergo 1,4 addition, again with high ee. Tsutomu Katsuki of Kyushu University originated (J. Am. Chem. Soc. 2008, 130, 10327) an Ir catalyst for the addition of diazoacetate 11 to alkenes such as 10 to give the cyclopropane 12 with high chemo-, enantio- and diastereoselectivity. Weiping Tang of the University of Wisconsin found (Angew. Chem. Int. Ed. 2008, 47, 8933) a silver catalyst that rearranged cyclopropyl diazo esters such as 13 to the cyclobutene 14 with high regioselectivity. Zhang-Jie Shi of Peking University demonstrated (J. Am. Chem. Soc. 2008, 130, 12901) that under oxidizing conditions, a Pd catalyst could cyclize 15 to 16. Sergio Castillón of the Universitat Rovira i Virgili, Tarragona devised (Organic Lett. 2008, 10, 4735) a Rh catalyst for the enantioselective cyclization of 17 to 18. Virginie Ratovelomanana-Vidal of the ENSCP Paris and Nakcheol Jeong of Korea University established (Adv. Synth. Cat. 2008, 350, 2695) conditions for the enantioselective intramolecular Pauson-Khand cyclization of 19 to give, after hydrolysis, the cyclopentenone 20. Quanrui Wang of Fudan University, Several elegant methods for the enantioselective transformation of preformed prochiral rings have been put forward. Derek R. Boyd of Queen’s University, Belfast devised (Chem. Commun. 2008, 5535) a Cu catalyst that effected allylic oxidation of cyclic alkenes such as 1 with high ee.

APA, Harvard, Vancouver, ISO, and other styles

4

Taber, Douglass F. "Substituted Benzenes: The Piers/Lau Synthesis of Hamigeran B." In Organic Synthesis. Oxford University Press, 2013. http://dx.doi.org/10.1093/oso/9780199965724.003.0064.

Full text

Abstract:

Govindasamy Sekar of the Indian Institute of Technology, Madras, developed ( Chem. Commun. 2011, 47, 5076) an environmentally friendly procedure for the amination of 1 to 2. Jens-Uwe Peters of Hoffmann-La Roche, Basel, showed (Tetrahedron Lett. 2011, 52, 749) that the Udenfriend protocol could be used to convert drugs such as 3 to their hydroxylated metabolites. Suman L. Jain and Anil K. Sinha of the Indian Institute of Petroleum reported (Chem. Commun. 2011, 47, 1610) complementary conditions for arene hydroxylation. Dimethyl aniline has been used, inter alia, as a nucleophile in enantioselective MacMillan conjugate addition. Zhong-Xia Wang of USTC established (Angew. Chem. Int. Ed. 2011, 50, 4901) that the quaternized salt 5 could participate in Negishi coupling. Mark R. Biscoe of the City College of New York discovered (Org. Lett. 2011, 13, 1218) that with a Ni catalyst, the secondary organozinc 9 will couple without rearrangement. Igor V. Alabugin of Florida State University devised (J. Org. Chem. 2011, 76, 1521) a radical-based protocol for replacing a phenolic OH with alkyl, to give 12. Petr Beier of the Academy of Sciences of the Czech Republic used (J. Org. Chem. 2011, 76, 4781) vicarious nucleophilic substitution followed by alkylation to convert 13 to 15. Robin B. Bedford of the University of Bristol developed (Angew. Chem. Int. Ed. 2011, 50, 5524) a Pd-catalyzed procedure for the ortho bromination of an anilide 16. Jin-Quan Yu of Scripps/La Jolla took advantage (J. Am. Chem. Soc. 2011, 133, 7652) of the energetic N-O bond of 19 to drive the functionalization of 18 to 20. Lei Liu of Tsinghua University devised (Org. Lett. 2011, 13, 3235) a Rh-mediated oxidative ortho coupling of the carbamate 21 with 22. Kohtaro Kirimura of Waseda University inserted (Chem. Lett. 2011, 40 , 206) the DNA for a novel Trichosporon decarboxylase into Escherichia coli and found that the resulting fermentation efficiently converted 24 into 25. The alternative Kolbe-Schmitt reaction requires high temperature and pressure. Sometimes, usually with more highly substituted benzene rings, creating the ring is worthwhile.

APA, Harvard, Vancouver, ISO, and other styles

5

Mistry, Harsh, Rashmi Thakor, Himanshu Polara, Tejas Shah, and Himanshu Bariya. "Biogenically efficient production and characterization of silver nanoparticles using the marine fungus Hamigera terricola along with their antimicrobial and antioxidative efficacy." In Nanotechnology and In Silico Tools, 89–96. Elsevier, 2024. http://dx.doi.org/10.1016/b978-0-443-15457-7.00002-2.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!