Academic literature on the topic 'Haliclona'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Haliclona.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Journal articles on the topic "Haliclona"
1
Abdo, D. A., J. I. McDonald, E. S. Harvey, J. Fromont, and G. A. Kendrick. "Neighbour and environmental influences on the growth patterns of two temperate Haliclonid sponges." Marine and Freshwater Research 59, no. 4 (2008): 304. http://dx.doi.org/10.1071/mf07165.
Full textAbstract:
Understanding the growth dynamics of an organism is central to understanding its ecology and biology. Sponges often dominate many subtidal habitats, however, determining their growth dynamics is often difficult owing to the plastic and amorphous morphologies that occur in many species. Two sympatric Haliclonid sponge species were examined using a novel photogrammetric technique to understand how environmental and competitive influences affect their growth. Sponges of both species were tagged and monitored over a 14-month period. Haliclona sp. 1 (green Haliclona) showed little variation in growth compared with Haliclona sp. 2 (brown Haliclona), which had a significant seasonal growth pattern. Both green and brown Haliclona grew a significant amount over the period of study (green Haliclona: 3.4% month–1; brown Haliclona: 6.0% month–1 (with neighbours) and 4.1% month–1 (without neighbours)). In both species, growth was not significantly influenced by competition from neighbours; rather, neighbouring organisms appeared to provide protection from adverse environmental conditions. The growth dynamics of both species have important implications for the maintenance of both species populations, particularly given the important habitat they provide for other organisms, and their potential exploitation for the supply of bioactive metabolites.
2
KIM, HYUNG JUNE, SANG-HUI LEE, and DONG WON KANG. "New species of the Genus Haliclona (Haplosclerida: Chalinidae) from Korea." Zootaxa 4347, no. 1 (November 10, 2017): 181. http://dx.doi.org/10.11646/zootaxa.4347.1.11.
Full textAbstract:
Two new marine sponges, Haliclona ieoensis sp. nov. and Haliclona sumenyoensis sp. nov. from the south Korea are described. Morphologically distinct from each other, both species are assigned to the genus Haliclona subgenus Haliclona. Haliclona ieoensis sp. nov. individuals are thickly encrusting to massive, beige colour and have small oscules flush on surface. Haliclona sumenyoesis sp. nov. individuals have a cylindrical tube with flexible stalk morphology, ivory colour, and large oscules. The description of these two new species brings the species of Haliclona (Haliclona) in Korea to five.
3
KIM, HYUNG JUNE, and DONG WON KANG. "Two New Species of the Genus Haliclona from Korea." Zootaxa 4890, no. 2 (December 2, 2020): 289–95. http://dx.doi.org/10.11646/zootaxa.4890.2.10.
Full textAbstract:
Two new marine sponges, Haliclona (Reniera) oceanus sp. nov. and Haliclona (Reniera) juckdoensis sp. nov. of the family Chalinidae were collected from Ieodo Ocean Research Station, Ulleung-do Island, Korea by SCUBA in 2016-2017. Morphologically distinct from each other, both species are assigned to the genus Haliclona subgenus Reniera. Haliclona (Reniera) oceanus sp. nov. is similar to H. (H.) ieoensis Kim et al. 2017 in shape, habitat, growth form, but it differs in color, ectosomal, choanosomal skeleton and spicule size. Haliclona (Reniera) juckdoensis sp. nov. is similar to H. (R.) hongdoensis Kang and Sim 2007 in habitat, ectosomal, choansomal skeleton but it differs in spicule size.
4
Fattorusso, Ernesto, Patrizia Ciminiello, Valeria Costantino, Silvana Magno, and Alfonso Mangoni. "Haliclonol, a New Tetrahydropyranone from the Caribbean Sponge Haliclona hogarthi." HETEROCYCLES 34, no. 4 (1992): 765. http://dx.doi.org/10.3987/com-91-5961.
Full text
5
SIM-SMITH, CARINA, CLEVELAND HICKMAN, JR, and MICHELLE KELLY. "New shallow-water sponges (Porifera) from the Galápagos Islands." Zootaxa 5012, no. 1 (August 2, 2021): 1–71. http://dx.doi.org/10.11646/zootaxa.5012.1.1.
Full textAbstract:
Twenty-five new species of shallow-water sponges are described from the Galápagos Islands, a province of Ecuador in the eastern Pacific Ocean. Sponges were photographed in situ and collected by SCUBA divers between 2001 and 2004. New species include: Acanthancora equiformis sp. nov., Acanthella saladinorum sp. nov., Cacospongia hermanorum sp. nov., Cinachyrella solis sp. nov., Ciocalypta bustamanti sp. nov., Clathria (Microciona) stellata sp. nov., Clathrina andreusi sp. nov., Craniella lissi sp. nov., Dragmacidon raeae sp. nov., Dragmacidon hendersoni sp. nov., Haliclona (Haliclona) clairae sp. nov., Haliclona (Haliclona) dianae sp. nov., Haliclona (Reniera) oberi sp. nov., Haliclona (Soestella) spuma sp. nov., Haliclona (Soestella) roslynae sp. nov., Hemimycale harlequinus sp. nov., Hemimycale nathani sp. nov., Higginsia johannae sp. nov., Neopetrosia eructans sp. nov., Leucilla agitata sp. nov., Penares angeli sp. nov., Prosuberites vansoesti sp. nov., Suberea esmerelda sp. nov., Tethya annona sp. nov. and Tethya sorbetus sp. nov. In addition, three species have been recorded for the first time from the Galápagos Islands: Chalinula cf. molitba (De Laubenfels, 1949), Chelonaplysilla violacea (Von Lendenfeld, 1883) and Tedania (Tedania) tropicalis Aguilar-Camacho, Carballo & Cruz-Barraza, 2018. This paper represents a significant contribution to our knowledge of the Porifera of the Galápagos Islands.
6
Elenkov, Ivaylo, Boryana Dragova, Stoitze Andreev, and Simeon Popov. "4α-Methyl Sterols from the Sponges Haliclona cinerea and Haliclona flavescens." Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology 118, no. 1 (September 1997): 155–57. http://dx.doi.org/10.1016/s0305-0491(97)00029-1.
Full text
7
Zhu, Jiaying, Yang Liu, Zijun Liu, Hao Wang, and Huawei Zhang. "Bioactive Nitrogenous Secondary Metabolites from the Marine Sponge Genus Haliclona." Marine Drugs 17, no. 12 (December 3, 2019): 682. http://dx.doi.org/10.3390/md17120682.
Full textAbstract:
Marine sponge genus Haliclona, one of the most prolific sources of natural products, contains over 600 species but only a small part of them had been classified and chemically investigated. On the basis of extensive literature search, this review firstly summarizes 112 nitrogenous secondary metabolites from classified and unclassified Haliclona sponges as well as from their symbiotic microorganisms. Most of these substances have only been found in Haliclona sponges, and display diverse bioactive properties with potential applications in new drug discovery.
8
Ode, Muhammad Fajrin, Muhammad Ramli, and Sahidin. "KAJIAN BIOAKTIVITAS ANTIBAKTERI DAN SENYAWA METABOLIT SEKUNDER SPONS LAUT Haliclona sp., DARI PERAIRAN TANJUNG TIRAM MORAMO UTARA, SULAWESI TENGGARA." Jurnal Sapa Laut (Jurnal Ilmu Kelautan) 4, no. 1 (May 16, 2019): 13. http://dx.doi.org/10.33772/jsl.v4i1.6803.
Full textAbstract:
Spons merupakan salah satu komponen organisme penyusun terumbu karang yang menghasilkan senyawa metabolit sekunder dan mempunyai potensi yang belum banyak dimanfaatkan. Penelitian ini bertujuan untuk mengidentifikasi senyawa metabolit sekunder dan bioaktivitas antibakteri ekstrak aseton spons Haliclona sp. terhadap tiga bakteri pathogen Salmonella typhi, Staphylococcus aureus dan Escherichia coli. Pengujian dan identifikasi senyawa metabolit sekunder dilakukan dengan menggunakan reagen (pereaksi). Sedangkan aktivitas antibakteri dilakukan dengan metode difusi cakram. Hasil penelitian menunjukkan bahwa ekstrak aseton spons Haliclona sp. teridentifikasi senyawa alkaloid, flavonoid, steroid, terpenoid, tannin (terkondensasi) dan saponin. Sedangkan kemampuan bioaktivitas antibakteri ekstrak aseton spons Haliclona sp. dikategorikan sedang terhadap bakteri S. typhi, dan dikategorikan lemah terhadap bakteri E. coli dan S. aureus. Ekstrak aseton dari spons Haliclona sp. menunjukkan potensi aktivitas inhibitor pertumbuhan bakteri patogen (antibakteri) terhadap S. typhi.Kata Kunci: Antibakteri, Senyawa Metabolit Sekunder, Spons.
9
Schellenberg, Johannes, Hans-Jürgen Busse, Martin Hardt, Patrick Schubert, Thomas Wilke, Peter Kämpfer, and Stefanie P. Glaeser. "Winogradskyella haliclonae sp. nov., isolated from a marine sponge of the genus Haliclona." International Journal of Systematic and Evolutionary Microbiology 67, no. 12 (December 1, 2017): 4902–10. http://dx.doi.org/10.1099/ijsem.0.002192.
Full text
10
CRUZ-BARRAZA, JOSÉ A., and JOSÉ L. CARBALLO. "A new species of Haliclona (Demospongiae: Haplosclerida) living in association with Geodia media Bowerbank (Mexican Pacific coast)." Zootaxa 1343, no. 1 (October 26, 2006): 43. http://dx.doi.org/10.11646/zootaxa.1343.1.2.
Full textAbstract:
Haliclona (Haliclona) sonorensis sp. nov. (Haplosclerida, Chalinidae) is described from different shallow water localities from the Mar de Cortés (Mexican Pacific coast). The new species is characterized by its thickly incrusting form, scarce and slightly elevated oscules, and pinkish violet color in life, in conjunction with internal characteristics such as an ectosomal skeleton formed by tangential isotropic unispicular reticulation and a regular choanosomal skeleton of unipaucispicular primary lines interconnected by unispicular secondary lines. Spicules are short and robust oxeas. Both the choanosomal skeleton and typical oxeas morphology are characteristic of the subgenus Haliclona. The new species has always been found growing in a mutualistic relationship with the sponge Geodia media Bowerbank, 1873.
Dissertations / Theses on the topic "Haliclona"
1
Carneiro, RÃmulo Farias. "Lectinas da esponja marinha Haliclona (Soestella) caerulea." Universidade Federal do CearÃ, 2013. http://www.teses.ufc.br/tde_busca/arquivo.php?codArquivo=12028.
Full textAbstract:
Conselho Nacional de Desenvolvimento CientÃfico e TecnolÃgicoLectinas podem ser definidas como proteÃnas/glicoporteÃnas que reconhecem carboidratos de maneira especÃfica, mas nÃo participam do metabolismo dos mesmos e nÃo pertencem a nenhuma das principais classes de imunoglobulinas. As lectinas sÃo proteÃnas ubÃquas, estando presente em todos os organismos conhecidos. Em cÃlulas animais, lectinas tÃm sido encontradas no citoplasma, no nÃcleo e associadas a membranas das mais diversas organelas e nos mais variados tipos celulares. Tais lectinas animais podem ser classificadas em famÃlias distintas com base em suas caracterÃsticas fÃsico quÃmicas, funÃÃo e especialmente em sua identidade de estrutura primÃria e terciÃria. O objetivo deste trabalho foi purificar duas novas lectinas da esponja marinha Haliclona (Soestella) caerulea e caracterizar estruturalmente uma delas. EspÃcimes de H.caerulea foram coletados na praia do paracuru, CearÃ. Duas lectinas (H-1 e H-3) foram isoladas por tÃcnicas clÃssicas de quÃmica de proteÃnas. A estrutura primÃria de uma delas foi determinada por espectrometria de massas e RACE. A atividade tÃxica das lectinas foi avaliada frente à nÃuplios de Artemia e cepas das bactÃrias Escherichia coli e Staphylococus aureus. H-1 e H-3 apresentaram caracterÃsticas distinhas da lectina previamente isolada de H. caerulea. H-1 à uma proteÃna monomÃrica de aporoximadamente 40 kDa enquanto que H-3 à uma proteÃna trimÃrica com cadeias com massa aproximada de 9, 16 e 18 kDa. H-3 aglutina eritrÃcitos humanos do tipo A e B e foi inibida GalNAc e PSM, H-1 aglutina diversos grupos sanguineos e nÃo pÃde ser inibida por nenhum aÃÃcar testado. H-1 foi tÃxica a naÃplios de Artemia (LC50=6,4 μg.mL-1) e H-3 foi considerada nÃo tÃxica (LC50=414,2 μg.mL-1). H-3 à uma proteÃna azul, pois interage com um cromÃforo de 597 Da com absorÃÃo mÃxima a 620 nm. A estrutura primÃria de H-3 foi determinada e revelou-se Ãnica, nÃo sendo conhecida nenhuma lectina com estrutura similar. H-3 apresenta um glicano hÃbrido composto por Hex7NAcHex7DeoxiHex2. A cadeia α de H-3 sofre um processamento proteolÃtico complexo que ainda nÃo foi completamente elucidado. AlÃm disso, H-3 foi cristalizada, mas nÃo foi possÃvel a obtenÃÃo de um padraÃo de difraÃÃo que permita a resoluÃÃo da estrutura. Em suma, duas novas lectinas foram isoladas e fora observado pela primeira vez a interaÃÃo entre uma lectina e um cromÃforo natural. Pela primeira vez tambÃm, fora determinada a composiÃÃo glicÃdica de uma lectina de esponja.
Lectins are proteins/glycoproteins that recognize carbohydrate of a specific way, but not participate in the metabolism of the same and do not belong to any of major classes of immunoglobulins. Lectins are ubiquitous proteins, present in all known organisms. In animal cells, lectins have been found in the cytoplasm, in the nucleous and as membrane-associated proteins, in diverse organelles and cells. Animal lectins can be classified into distinct families based on their physicochemical characteristics, especially in their function and identity of primary and tertiary structure. The aim of this study was to purify, characterize structural and biologically new lectins from the marine sponge Haliclona (Soestella) caerulea. H. caerulea specimens were collected in Paracuru beach, CearÃ. Two lectins (H-1 and H-3) were isolated by classical techniques of protein chemistry. The primary structure of H-3 was determined by mass spectrometry and RACE. The toxic activity of lectins was evaluated against Artemia nauplii and Escherichia coli and Staphylococcus aureus strains. H-1 and H-3 showed distinct characteristics of the lectin previously isolated from H. caerulea. H-1 is a monomeric protein of 40 kDa whereas H-3 is a heterogeneus protein with chains of 9, 16 and 18 kDa. H-3 binds human erythrocytes of A and B type and was inhibited by GalNAc and PSM, H-1 binds different blood groups and could not be inhibited by any sugar tested. H-1 was toxic to Artemia nauplii (LC50 = 6.4 μg.mL-1) and H-3 was not considered toxic (LC50 = 414.2 μg.mL-1). H-3 is a blue protein that interacts with a chromophore of 597 Da of maximum absorbance at 620 nm. The primary structure of H-3 revealed a unique amino acid sequence no similar to any animal lectins known. H-3 has a hybrid glycan comprising by Hex7NAcHex7DeoxiHex2. The α-chain of H-3 undergoes complex proteolytic processing that not been fully elucidated. Moreover, H-3 was crystallized, but was not possible to obtain a diffraction pattern that permits solving the structure. In short, two new lectins were isolated and out first observed the interaction between a lectin and natural chromophore. Furthermore, for the first time given the composition glicidic out of a sponge lectin.
2
Carneiro, Rômulo Farias. "Lectinas da esponja marinha Haliclona (Soestella) caerulea." reponame:Repositório Institucional da UFC, 2013. http://www.repositorio.ufc.br/handle/riufc/14386.
Full textAbstract:
CARNEIRO, R. F. Lectinas da esponja marinha Haliclona (Soestella) caerulea. 2013. 127 f. Dissertação (Mestrado em Bioquímica) - Centro de Ciências, Universidade Federal do Ceará, Fortaleza, 2013.Submitted by Daniel Eduardo Alencar da Silva (dealencar.silva@gmail.com) on 2015-01-22T17:27:45Z No. of bitstreams: 1 2013_dis_rfcarneiro.pdf: 4260974 bytes, checksum: c0be525bfa10b20a04540ce33ef61d2e (MD5)
Approved for entry into archive by José Jairo Viana de Sousa(jairo@ufc.br) on 2015-12-08T21:36:29Z (GMT) No. of bitstreams: 1 2013_dis_rfcarneiro.pdf: 4260974 bytes, checksum: c0be525bfa10b20a04540ce33ef61d2e (MD5)
Made available in DSpace on 2015-12-08T21:36:29Z (GMT). No. of bitstreams: 1 2013_dis_rfcarneiro.pdf: 4260974 bytes, checksum: c0be525bfa10b20a04540ce33ef61d2e (MD5) Previous issue date: 2013
Lectins are proteins/glycoproteins that recognize carbohydrate of a specific way, but not participate in the metabolism of the same and do not belong to any of major classes of immunoglobulins. Lectins are ubiquitous proteins, present in all known organisms. In animal cells, lectins have been found in the cytoplasm, in the nucleous and as membrane-associated proteins, in diverse organelles and cells. Animal lectins can be classified into distinct families based on their physicochemical characteristics, especially in their function and identity of primary and tertiary structure. The aim of this study was to purify, characterize structural and biologically new lectins from the marine sponge Haliclona (Soestella) caerulea. H. caerulea specimens were collected in Paracuru beach, Ceará. Two lectins (H-1 and H-3) were isolated by classical techniques of protein chemistry. The primary structure of H-3 was determined by mass spectrometry and RACE. The toxic activity of lectins was evaluated against Artemia nauplii and Escherichia coli and Staphylococcus aureus strains. H-1 and H-3 showed distinct characteristics of the lectin previously isolated from H. caerulea. H-1 is a monomeric protein of 40 kDa whereas H-3 is a heterogeneus protein with chains of 9, 16 and 18 kDa. H-3 binds human erythrocytes of A and B type and was inhibited by GalNAc and PSM, H-1 binds different blood groups and could not be inhibited by any sugar tested. H-1 was toxic to Artemia nauplii (LC50 = 6.4 μg.mL-1) and H-3 was not considered toxic (LC50 = 414.2 μg.mL-1). H-3 is a blue protein that interacts with a chromophore of 597 Da of maximum absorbance at 620 nm. The primary structure of H-3 revealed a unique amino acid sequence no similar to any animal lectins known. H-3 has a hybrid glycan comprising by Hex7NAcHex7DeoxiHex2. The α-chain of H-3 undergoes complex proteolytic processing that not been fully elucidated. Moreover, H-3 was crystallized, but was not possible to obtain a diffraction pattern that permits solving the structure. In short, two new lectins were isolated and out first observed the interaction between a lectin and natural chromophore. Furthermore, for the first time given the composition glicidic out of a sponge lectin.
Lectinas podem ser definidas como proteínas/glicoporteínas que reconhecem carboidratos de maneira específica, mas não participam do metabolismo dos mesmos e não pertencem a nenhuma das principais classes de imunoglobulinas. As lectinas são proteínas ubíquas, estando presente em todos os organismos conhecidos. Em células animais, lectinas têm sido encontradas no citoplasma, no núcleo e associadas a membranas das mais diversas organelas e nos mais variados tipos celulares. Tais lectinas animais podem ser classificadas em famílias distintas com base em suas características físico químicas, função e especialmente em sua identidade de estrutura primária e terciária. O objetivo deste trabalho foi purificar duas novas lectinas da esponja marinha Haliclona (Soestella) caerulea e caracterizar estruturalmente uma delas. Espécimes de H.caerulea foram coletados na praia do paracuru, Ceará. Duas lectinas (H-1 e H-3) foram isoladas por técnicas clássicas de química de proteínas. A estrutura primária de uma delas foi determinada por espectrometria de massas e RACE. A atividade tóxica das lectinas foi avaliada frente à náuplios de Artemia e cepas das bactérias Escherichia coli e Staphylococus aureus. H-1 e H-3 apresentaram características distinhas da lectina previamente isolada de H. caerulea. H-1 é uma proteína monomérica de aporoximadamente 40 kDa enquanto que H-3 é uma proteína trimérica com cadeias com massa aproximada de 9, 16 e 18 kDa. H-3 aglutina eritrócitos humanos do tipo A e B e foi inibida GalNAc e PSM, H-1 aglutina diversos grupos sanguineos e não pôde ser inibida por nenhum açúcar testado. H-1 foi tóxica a naúplios de Artemia (LC50=6,4 μg.mL-1) e H-3 foi considerada não tóxica (LC50=414,2 μg.mL-1). H-3 é uma proteína azul, pois interage com um cromóforo de 597 Da com absorção máxima a 620 nm. A estrutura primária de H-3 foi determinada e revelou-se única, não sendo conhecida nenhuma lectina com estrutura similar. H-3 apresenta um glicano híbrido composto por Hex7NAcHex7DeoxiHex2. A cadeia α de H-3 sofre um processamento proteolítico complexo que ainda não foi completamente elucidado. Além disso, H-3 foi cristalizada, mas não foi possível a obtenção de um padraão de difração que permita a resolução da estrutura. Em suma, duas novas lectinas foram isoladas e fora observado pela primeira vez a interação entre uma lectina e um cromóforo natural. Pela primeira vez também, fora determinada a composição glicídica de uma lectina de esponja.
3
Abdo, David A. "Maintenance and structuring of two temperate Haliclonid sponge populations." University of Western Australia. School of Plant Biology, 2007. http://theses.library.uwa.edu.au/adt-WU2008.0197.
Full textAbstract:
[Truncated abstract] Sponges have an invaluable ecological importance through the provision of shelter and habitat, consolidation of reefs, bio-erosion, and in benthic-pelagic coupling processes. In addition, sponges are known to be an incredible source of compounds with bio-medicinal and commercial applications. Despite their ecological and economic importance, our understanding of the processes which maintain and structure sponge populations is severely lacking compared to other sessile invertebrates (e.g. Cnidarians). This study examines the processes which help maintain and the factors which structure the populations of two sympatric Haliclona species (Demospongiae; Haplosclerida; Chalinidae) at Hamelin Bay on the south west coast of Australia. In addition, the importance of both species to the broader marine community is examined. The reproductive biology of both species was determined from histological sections taken from each species over two years at Hamelin Bay. No evidence of asexual reproduction was observed in either species. Sexual reproduction occurred from November to April in Haliclona sp. 1 (hereafter green Haliclona) and November to May in Haliclona sp. 2 (hereafter brown Haliclona). The green Haliclona is viviparous with both gonochoric and hermaphroditic individuals observed in the population. The brown Haliclona is also viviparous with separate sexes. The onset and progression of reproduction in both species corresponded to increases in water temperature and photoperiod, but only decreasing wave height showed a significant correlation to gametogenesis. ... A significant (P < 0.05) difference in concentration between seasons was also observed, suggesting environmental and physiological factors affect the production of salicylihalamide A in the green Haliclona. The importance of each species to the marine environment was assessed by investigating the endofauna inhabiting each species across their known range ( [approx. ]1000 km's). A total of 948 and 287 endofaunal individuals were found associated with the green and brown Haliclona, respectively. Twenty four endofaunal taxa were found (from mysid shrimps to teleost fish), and the endofaunal assemblages of each species were significantly different. However, only the endofaunal assemblage associated with the green Haliclona varied among locations. Overall, this study demonstrates that the populations of both species are maintained by limited sexual reproductive output and larval dispersal. Abiotic factors (e.g. water temperature, wave exposure) influence the growth and physiology of both species, which is intimately connected to their abilities to reproduce. This has important consequences for the species populations with regard to their resilience to environmental change, and potential for harvesting of biomass for supply of bioactive compounds. Additionally, both species provide important habitats for many other organisms. The findings highlight the need for a detailed understanding of the ecology of potentially exploitable sponge species, to ensure their conservation and limit the impact on the organisms which rely on the sponges.
4
Lachance, Daniel. "The cytology of a Haliclona oculata (Demospongiae, Haplosclerida) /." Thesis, McGill University, 1985. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=63362.
Full text
5
Tribalat, Marie-Aude. "Métabolismes spécialisés d’éponges méditerranéennes du genre Haliclona Grant, 1836." Thesis, Université Côte d'Azur (ComUE), 2016. http://www.theses.fr/2016AZUR4072/document.
Full textAbstract:
Depuis une cinquantaine d’années, de nombreuses études ont décrit les spongiaires comme de formidables ressources de produits naturels originaux. Ces découvertes ont attisé la curiosité de nombreux scientifiques issus de domaines variés (chimie, biochimie, biologie moléculaire) qui mettent leurs connaissances en commun afin de comprendre le fonctionnement de ces animaux si particuliers. Les travaux envisagés dans ce manuscrit portent sur les éponges du genre Haliclona issu de l’ordre des Haplosclérides. En effet, ce groupe taxonomique révèle des familles de molécules très particulières, notamment les alcaloïdes 3-AP et les polyacétylènes, qui présentent un potentiel pharmacologique à exploiter. En outre la diversité chimique retrouvée au sein de ce genre remet en question la validité de la classification actuelle des Haplosclérides déjà discutée par les données de biologie moléculaire. L’intérêt particulier porté à ces composés originaux concerne également les voies métaboliques permettant d’aboutir à leur biosynthèse. Ainsi les alcaloïdes 3-AP ne trouvant aucun équivalent notamment dans le monde terrestre, la description de leur voie de biosynthèse n’a alors été envisagée que sous forme d’hypothèses. Afin d’éclaircir les différentes problématiques posées par ce groupe de spongiaires, les études menées pendant ce doctorat ont fait appel à des méthodes et techniques variées tels que les méthodes d’extraction et d’analyses de la chimie des produits naturels classique, l’outil récent qu’est la métabolomique ou encore les expériences de « feeding » et l’utilisation de composés radio-marquésSince about fifty years, several studies described sponges as astounding resources of original natural products. These discoveries aroused scientist’s curiosity in various areas (chemistry, biochemistry, molecular biology) and to understand these animal’s functioning, they share their knowledge. The proposed work in this manuscript, focus on sponges of genus Haliclona from the order Haplosclerida. Indeed, this taxonomic group reveal peculiar chemical families, including 3-AP alkaloids and polyacetylenic compounds, displaying pharmacological potential to be exploited. Besides, chemicalDépôt de thèseDonnées complémentairesdiversity encountered in this genus challenge the actual classification of Haplosclerida group already disputed by biomolecular data. The particular interest in these original compounds also concerns metabolic pathways leading to their biosynthesis. In this way, 3-AP alkaloids, which don’t have any equivalent particularly in terrestrial area, the description of their biosynthesis pathway was only considered by hypothesis. To resolve various problematics proposed by this sponges’ group, studies conducted through this PhD appeal to several methods and technics like usual natural products chemistry extraction and analytical technics, recent tool named metabolomic or feeding experiments with radiolabelled compounds
6
Salmoun, Mostafa. "Contribution à l'étude des métabolites secondaires d'éponges des genres Hyrtios et Haliclona." Doctoral thesis, Universite Libre de Bruxelles, 2002. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/211409.
Full text
7
Schmidt, Gesine [Verfasser], and Matthias [Akademischer Betreuer] Köck. "Secondary Metabolites in the Arctic Sponge Haliclona viscosa - Spatial and Temporal Variation / Gesine Schmidt ; Betreuer: Matthias Köck." Braunschweig : Technische Universität Braunschweig, 2010. http://d-nb.info/117582688X/34.
Full text
8
Ahamada, Kadiria. "Stratégies biomimétiques en vue de la synthèse totale de deux substances naturelles polycycliques complexes : la bipléiophylline et l'haliclonine A." Thesis, Paris 11, 2014. http://www.theses.fr/2014PA114807/document.
Full textAbstract:
Les travaux présentés concernent dans une première partie la synthèse biomimétique d’un alcaloïde indolomonoterpénique : la bipléiophylline. La bipléiophylline est le résultat de l’assemblage complexe de deux unités indoliques identiques ancrées sur une plateforme aromatique. Une stratégie générale de synthèse biomimétique de la bipléiophylline consistant i) à la synthèse de l’unité indolique pléiocarpamine et ii) à l’oxydation de l’acide 2,3-dihydroxybenzoïque a été envisagée. L’accès au squelette complexe de la pléiocarpamine a été étudié selon plusieurs stratégies de synthèse totale mais également par hémisynthèse. Parallèlement une étude des conditions d’oxydation notamment par électrochimie de l’acide 2,3-dihydroxybenzoïque ont permis de déterminer et caractériser son potentiel d’oxydation et de mettre au point les conditions de formation de sa forme oxydée. La seconde partie est consacrée à la synthèse biomimétique d’un modèle du cœur central de l’haliclonine A, un alcaloïde de la famille des manzamines. La synthèse de plusieurs précurseurs a été réalisée ainsi que l’étude de l’étape clé de double addition nucléophile sur un 5,6-dihydropyridiniumOur work deals in the first part with a biomimetic synthesis of bipleiophyllin, an indolomonoterpenic alkaloid. The bipleiophyllin is the result of a complex anchorage of two identical indolic subunits on an aromatic platform. A general strategy for the biomimetic synthesis of bipleiophyllin consisting of i) the synthesis of the indolic unit pleiocarpamin and ii) the oxidation of 2,3-dihydroxybenzoic acid; was considered. Access to the complex skeleton of pleiocarpamin has been studied by different total synthesis strategies but also by hemisynthesis. Meanwhile this work, a study of the oxidation conditions of 2,3-dihydroxybenzoic acid including by electrochemistry, helped identify and characterize its oxidation potential and develop the required conditions to obtain its oxidized form. The second part is devoted to the biomimetic synthesis of a model compound, mimic of the central core of haliclonin A, an alkaloid of the family of manzamins. The synthesis of several precursors and the study of the key step consisting in a double nucleophilic addition to a 5,6-dihydropyridinium were done
9
Mani, Luke. "Antiplasmodial compounds from marine sponges of the Solomon Islands." Toulouse 3, 2010. http://www.theses.fr/2010TOU30280.
Full textAbstract:
Dans le cadre de la recherche de nouvelles molécules antipaludiques, une espèce d'Haliclona et quatre lots de l'éponge Aplysina ianthelliformis ont été étudiées pour fournir 22 composés, dont sept sont nouveaux 141-147. Un produit connu, l'haliclonacyclamine A 129, qui a montré ici une activité in vitro sur des souches de Plasmodium falciparum FCB1 résistantes à la chloroquine avec une CI50 de 98nM et un index de sélectivité (activité Antipalsmodiale/cytotoxicité) de 57 et 67 déterminé respectivement sur cellules MVF7 et Véro. Testée in vivo sur le modèle souris, l'haliclonacyclamine A 129 a montré 48% d'inhibition de la parasitémie le 4ème jour après 3 jours de traitement à 10mg/Kg/jour administré par voie intra-péritonéale à des souris Swiss femelles infectées par P. Vinckei petteri. Les échantillons d'A. Ianthelliformis ont fourni 21 produits, tous sauf deux (aureol 137 et aplysterol 138) appartenant à la série des bromotyrosines. Ces composés 35a, 36, 130-147 montrent une faible activité in vitro sur les souches résistantes ou sensibles à la chloroquine, P. Falciparum FCB1 et 3D7 respectivement, avec des CI50 allant de 0. 9 à 44µM. Tous les composés dérivés de la bromotyrosine manquent de sélectivité, sauf l'araplysillin I 139 qui présente un faible index de sélectivité de 5,5 et 6,5 respectivement sur cellules MCF7 et Vero, et une CI50 = 4,5µM sur P. Falciparum FCB1. Tous ces produits présentent une faible activité sur la Protéinefarnésyletransférase (PFTase) ; le composé le plus actif, l'aerophobin II 135, a une CI50 = 4. 9µM. L'inactivité de la molécule 144 suggère l'importance du motif isoxazolinique dans l’activité sur PFTaseIn a search for new antiplasmodial compounds, one Haliclona and four Aplysina ianthelliformis sponges were chemically investigated to furnish 21 compounds, seven of which are novel ones 141-147. The Haliclona sponge gave the known product, haliclonacylamine A 129 which exhibits potent in vitro activity against the chloroquine-resistant strain, Plasmodium falciparum FCB-1 with an IC50 of 98 nM and a strong selectivity index of 57 and 67 (determined as antiplasmodial activity/ cytotoxicity). In the in vivo mice model, haliclonacyclamine A 129 gave 45% parasitaemia inhibition on the fourth day following three days of treatment at 10 mg/Kg/day administered intra-peritoneally to Swiss female mice infected with P. Vinckei petteri. The A. Ianthelliformis sponges furnished 20 compounds, all but two (aureol 137 and aplysterol 138) of which are bromotyrosine derivatives. All bromotyrosine-derived compounds; 35a, 36, 130-147 exhibit mild in vitro activities against the chloroquine-resistant and sensitive strains, P. Falciparum FCB-1 and 3D7 respectively, with IC50s ranging between 0. 9 – 50. 5 µM. All bromotyrosine compounds lack selectivity except for araplysillin I 139 which has a weak selectivity index of 5. 5 and 6. 5 (measured for MCF-7 and Vero cells respectively) and an IC50 value of 4. 5 µM against P. Falciparum, FCB-1. All bromotyrosine derivatives, except for the novel compound 144, also exhibit weak Protein farnesyltransferase (PFTase) inhibitory activity; the most active, aerophobin II 135, has an IC50 of 8. 0 µM. The inactivity of compound 144 suggests the importance of the isoxazoline motif in conferring PFTase activity in bromotyrosine compounds
10
Pichon, Emmanuel. "Recherche de molécules naturelles bioactives issues de la biodiversité marine de la zone sud-ouest de l'océan Indien." Thesis, La Réunion, 2016. http://www.theses.fr/2016LARE0018/document.
Full textAbstract:
Les travaux de thèse présentés dans ce manuscrit portent sur l'étude de quatre éponges marines issues de la zone Sud-Ouest de l'Océan Indien : Plakortis kenyensis, Theonella swinhoei, Haliclona fascigera et Fascaplysinopsis reticulata. Les travaux entrepris comprenaient l'étude chimique de ces éponges incluant l'extraction, l'isolement et l'identification des métabolites secondaires par différentes techniques chromatographiques (CLMP, CLHP...) et spectroscopiques (UV-visible, HRMS, RMN 1D et 2D...). Douze métabolites secondaires ont été isolés de ces éponges dont six de structures nouvelles, à savoir : l'acide 2,5-époxydocosan-6-én-21-ynoïque (HF1), un acide gras atypique isolé de l'éponge Haliclona fascigera ; la 8-oxo-tryptamine (FR2), la 6,6’-bis-(débromo)- gelliusine F (FR3), la 6-bromo-2’-déméthyl-3’-N-méthyl-1’,8-dihydroaplysinopsine (FR6), la 5,6-dibromo-2’- déméthyl-3’-N-méthyl-1’,8-dihydroaplysinopsine (FR7) et la 5,6-dibromo-3’-déimino-2’-déméthyl-3’-oxo-1’,8- dihydroaplysinopsine (FR8), cinq alcaloïdes indoliques isolés de l'éponge Fascaplysinopsis reticulata. La valorisation des molécules isolées a ensuite été envisagée via l'évaluation de leurs activités biologiques. Parmi les douze molécules isolées, sept ont montré une activité antipaludique, trois une activité inhibitrice du quorum sensing de la bactérie bioluminescente Vibrio harveyi et cinq une activité anti-microfouling par inhibition de l'adhésion et/ou de la croissance de souches microbiennes marinesThe work described in this manuscript concerns four sponges from the South-West Indian Ocean: Plakortis kenyensis, Theonella swinhoei, Haliclona fascigera and Fascaplysinopsis reticulata. The chemical study of the sponges including extraction, isolation and identification of secondary metabolites was undertaken using various chromatographic (MPLC, HPLC ...) and spectroscopic (UV-visible, HRMS, 1D and 2D NMR ...) techniques. Twelve secondary metabolites including six new molecules were isolated from these sponges. The new molecules are: 2,5-époxydocosan-6-en-21-ynoic acid (HF1) an unusual fatty acid isolated from the sponge Haliclona fascigera; 8-oxo-tryptamine (FR2), 6,6'-bis (debromo)-gelliusine F (FR3), 6-bromo-2'-demethyl-3'-N- methyl-1',8-dihydroaplysinopsine (FR6), 5,6-dibromo-2'-demethyl-3'-N-methyl-1',8-dihydroaplysinopsine (FR7) and 5,6-dibromo-3’-deimino-2’-demethyl-3’-oxo-1’,8-dihydroaplysinopsine (FR8), five indole alkaloids isolated from the sponge Fascaplysinopsis reticulata. The biological activities of the isolated molecules were then evaluated. Among the twelve isolated molecules, seven were active against the malaria parasite Plasmodium falciparum, three were identified as inhibitors of the quorum sensing-regulated bioluminescence in Vibrio harveyi and five, showing marine bacterial adhesion and/or growth inhibition, exhibited potential anti- microfouling activity
Book chapters on the topic "Haliclona"
1
Jones, W. C. "Skeletal Variation in Embryo-Containing Specimens of Haliclona Rosea (Bowerbank) from Anglesey, North Wales." In Taxonomy of Porifera, 101–24. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-70892-3_6.
Full text
2
Jones, W. C. "Monthly Variations in the Size of Spicules of the Haplosclerid Sponge, Haliclona rosea (Bowerbank)." In Fossil and Recent Sponges, 404–20. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-75656-6_33.
Full textConference papers on the topic "Haliclona"
1
Li, Hanwei, Bin Wang, and Yongmei Li. "An unusual mercapto-containing and three known diketopiperazines from the marine sponge Haliclona sp." In 2011 International Conference on Human Health and Biomedical Engineering (HHBE). IEEE, 2011. http://dx.doi.org/10.1109/hhbe.2011.6028393.
Full text
2
Bovio, Elena, Marina Rosenthal Pereira Lima, Benoît Industri, Pham Giang Nam, Laurent Lapeyre, Renaud Canaguier, Laurent Boyer, Mohamed Mehiri, and Michel Ponchet. "From the Sea to the Field: The Case Study of the Mycobiota Associated to the Marine Sponge <em>Haliclona fulva</em> and its Interest as Biocontrol Agent Source for Agriculture <sup>†</sup>." In 1st International Electronic Conference on Biological Diversity, Ecology and Evolution. Basel, Switzerland: MDPI, 2021. http://dx.doi.org/10.3390/bdee2021-09466.
Full text