Relevant bibliographies by topics / H-1NF / Journal articles

Journal articles on the topic 'H-1NF'

To see the other types of publications on this topic, follow the link: H-1NF.
Author: Grafiati
Published: 20 June 2024

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the top 50 journal articles for your research on the topic 'H-1NF.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.

1

Michael, C. A., J. Howard, and B. D. Blackwell. "The MOSS camera on H-1NF." Review of Scientific Instruments 72, no. 1 (January 2001): 1034–37. http://dx.doi.org/10.1063/1.1326903.

Full text
APA, Harvard, Vancouver, ISO, and other styles
2

Dettrick, S. A., H. J. Gardner, and S. L. Painter. "Monte Carlo Transport Simulation Techniques for Stellarator Fusion Experiments." Australian Journal of Physics 52, no. 4 (1999): 715. http://dx.doi.org/10.1071/ph98106.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
We describe an implementation of a particle orbit-following simulation approach to the Monte Carlo calculation of neoclassical transport coecients which has been developed for application to the H-1NF Heliac. We compare and contrast some Monte Carlo transport coecient estimators that can be used in such computer codes, from both physical and computational perspectives, and we make recommendations for their use. Transport coecient calculations are performed for the H-1NF in conditions that will be available after the full National Facility upgrade.
3

Glass, F., J. Howard, and B. Blackwell. "Visible emission tomography in the H-1NF heliac." IEEE Transactions on Plasma Science 33, no. 2 (April 2005): 472–73. http://dx.doi.org/10.1109/tps.2005.845900.

Full text
APA, Harvard, Vancouver, ISO, and other styles
4

Harris, J. H., M. G. Shats, B. D. Blackwell, W. M. Solomon, D. G. Pretty, S. M. Collis, J. Howard, H. Xia, C. A. Michael, and H. Punzmann. "Fluctuations and stability of plasmas in the H-1NF heliac." Nuclear Fusion 44, no. 2 (January 12, 2004): 279–86. http://dx.doi.org/10.1088/0029-5515/44/2/008.

Full text
APA, Harvard, Vancouver, ISO, and other styles
5

Kumar, Santhosh T. A., Boyd D. Blackwell, John Howard, and Jeffrey H. Harris. "Core magnetic islands and plasma confinement in the H-1NF heliac." Physics of Plasmas 17, no. 8 (August 2010): 082503. http://dx.doi.org/10.1063/1.3474946.

Full text
APA, Harvard, Vancouver, ISO, and other styles
6

Haskey, S. R., B. D. Blackwell, B. Seiwald, and J. Howard. "Visible light tomography of MHD eigenmodes in the H-1NF stellarator using magnetic coordinates." Nuclear Fusion 54, no. 8 (July 23, 2014): 083031. http://dx.doi.org/10.1088/0029-5515/54/8/083031.

Full text
APA, Harvard, Vancouver, ISO, and other styles
7

Kumar, Santhosh T. A., Boyd D. Blackwell, and Jeffrey H. Harris. "Wire tomography in the H-1NF heliac for investigation of fine structure of magnetic islands." Review of Scientific Instruments 78, no. 1 (January 2007): 013501. http://dx.doi.org/10.1063/1.2424453.

Full text
APA, Harvard, Vancouver, ISO, and other styles
8

Bertram, J., M. J. Hole, D. G. Pretty, B. D. Blackwell, and R. L. Dewar. "A reduced global Alfvén eigenmodes model for Mirnov array data on the H-1NF heliac." Plasma Physics and Controlled Fusion 53, no. 8 (June 23, 2011): 085023. http://dx.doi.org/10.1088/0741-3335/53/8/085023.

Full text
APA, Harvard, Vancouver, ISO, and other styles
9

Haskey, S. R., B. D. Blackwell, C. Nührenberg, A. Könies, J. Bertram, C. Michael, M. J. Hole, and J. Howard. "Experiment-theory comparison for low frequency BAE modes in the strongly shaped H-1NF stellarator." Plasma Physics and Controlled Fusion 57, no. 9 (August 12, 2015): 095011. http://dx.doi.org/10.1088/0741-3335/57/9/095011.

Full text
APA, Harvard, Vancouver, ISO, and other styles
10

Kumar, S. T. A., B. D. Blackwell, J. Howard, and J. H. Harris. "Spontaneous transition of core radial electric field driven by magnetic islands in the H-1NF heliac." Nuclear Fusion 51, no. 8 (June 23, 2011): 083003. http://dx.doi.org/10.1088/0029-5515/51/8/083003.

Full text
APA, Harvard, Vancouver, ISO, and other styles
11

Collis, S. M., J. Howard, G. B. Warr, C. A. Michael, J. H. Harris, B. D. Blackwell, and D. G. Pretty. "Studies of resonantly produced plasmas in the H-1NF heliac using a far-infrared scanning interferometer." Review of Scientific Instruments 74, no. 3 (March 2003): 1629–32. http://dx.doi.org/10.1063/1.1538360.

Full text
APA, Harvard, Vancouver, ISO, and other styles
12

Petržílka, V. "Theoretical estimates of radial electric fields and plasma rotation induced in H-1NF by RF waves." Czechoslovak Journal of Physics 46, no. 11 (November 1996): 1085–91. http://dx.doi.org/10.1007/bf01690037.

Full text
APA, Harvard, Vancouver, ISO, and other styles
13

Bolsoni-Lopes, Andressa, William T. Festuccia, Talita S. M. Farias, Patricia Chimin, Francisco L. Torres-Leal, Priscilla B. M. Derogis, Paula B. de Andrade, et al. "Palmitoleic acid (n-7) increases white adipocyte lipolysis and lipase content in a PPARα-dependent manner." American Journal of Physiology-Endocrinology and Metabolism 305, no. 9 (November 1, 2013): E1093—E1102. http://dx.doi.org/10.1152/ajpendo.00082.2013.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
We investigated whether palmitoleic acid, a fatty acid that enhances whole body glucose disposal and suppresses hepatic steatosis, modulates triacylglycerol (TAG) metabolism in adipocytes. For this, both differentiated 3T3-L1 cells treated with either palmitoleic acid (16:1n7, 200 μM) or palmitic acid (16:0, 200 μM) for 24 h and primary adipocytes from wild-type or PPARα-deficient mice treated with 16:1n7 (300 mg·kg−1·day−1) or oleic acid (18:1n9, 300 mg·kg−1·day−1) by gavage for 10 days were evaluated for lipolysis, TAG, and glycerol 3-phosphate synthesis and gene and protein expression profile. Treatment of differentiated 3T3-L1 cells with 16:1n7, but not 16:0, increased basal and isoproterenol-stimulated lipolysis, mRNA levels of adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) and protein content of ATGL and pSer660-HSL. Such increase in lipolysis induced by 16:1n7, which can be prevented by pharmacological inhibition of PPARα, was associated with higher rates of PPARα binding to DNA. In contrast to lipolysis, both 16:1n7 and 16:0 increased fatty acid incorporation into TAG and glycerol 3-phosphate synthesis from glucose without affecting glyceroneogenesis and glycerokinase expression. Corroborating in vitro findings, treatment of wild-type but not PPARα-deficient mice with 16:1n7 increased primary adipocyte basal and stimulated lipolysis and ATGL and HSL mRNA levels. In contrast to lipolysis, however, 16:1n7 treatment increased fatty acid incorporation into TAG and glycerol 3-phosphate synthesis from glucose in both wild-type and PPARα-deficient mice. In conclusion, palmitoleic acid increases adipocyte lipolysis and lipases by a mechanism that requires a functional PPARα.
14

Kashkarov, Egor B., Maxim S. Syrtanov, Tatyana L. Murashkina, Alexander V. Kurochkin, Yulia Shanenkova, and Aleksei Obrosov. "Hydrogen Sorption Kinetics of SiC-Coated Zr-1Nb Alloy." Coatings 9, no. 1 (January 8, 2019): 31. http://dx.doi.org/10.3390/coatings9010031.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
This paper describes the influence of silicon carbide (SiC) coating on hydrogen sorption kinetics of zirconium alloy E110 (Zr-1Nb). Amorphous SiC coating of 1.5-μm thickness was deposited on Zr-1Nb alloy substrate by direct current magnetron sputtering of composite cathode. Hydrogen absorption by SiC-coated Zr-1Nb alloy significantly decreased due to low hydrogen permeability of the coating. Hydrogenation tests show that SiC coating provides protective properties against hydrogen permeation in the investigated temperature range of 350–450 °C. It was shown that hydrogenation of uncoated Zr-1Nb leads to formation of δ hydrides at 350 °C and δ and γ hydrides at higher temperatures whereas in the SiC-coated Zr-1Nb alloy only δ hydrides formed. Gradient hydrogen distribution through the SiC coating and H trapping in the carbon-rich interface was observed. The adhesion strength of the coating was ~5 N. Hydrogenation up to 450 °C for 5 h does not degrade the adhesion properties during scratch testing.
15

Januschowski, K., and H. Wilhelm. "Optikusneuropathie mit konzentrischer Gesichtsfeldeinengung nach lebensbedrohlicher H 1N1-Influenza." Klinische Monatsblätter für Augenheilkunde 227, no. 11 (November 2010): 860–61. http://dx.doi.org/10.1055/s-0029-1245604.

Full text
APA, Harvard, Vancouver, ISO, and other styles
16

Zhou, Ayang, Guangle Hu, Keying Guo, Mengnan Zhang, and Xiangnan Liu. "Fabrication of Organic Solvent Nanofiltration Membrane through Interfacial Polymerization Using N-Phenylthioure as Monomer for Dimethyl Sulfoxide Recovery." Separations 10, no. 3 (March 7, 2023): 179. http://dx.doi.org/10.3390/separations10030179.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
To recover dimethyl sulfoxide, an organic solvent nanofiltration membrane is prepared via the interfacial polymerization method. N-Phenylthiourea (NP)is applied as a water-soluble monomer, reacted with trimesoyl chloride (TMC) on the polyetherimide substrate crosslinked by ethylenediamine. The results of attenuated total reflectance-fourier transform infrared spectroscopy and X-ray electron spectroscopy confirm that N-Phenylthiourea reacts with TMC. The membrane morphology is investigated through atomic force microscopy and scanning electronic microscopy, respectively. The resultant optimized TFC membranes NF-1NP exhibited stable permeance of about 4.3 L m−2 h−1 bar-1 and rejection of 97% for crystal violet (407.98 g mol−1) during a 36 h continuous separation operation. It was also found that the NF-1NP membrane has the highest rejection rate in dimethyl sulfoxide (DMSO), and the rejection rates in methanol, acetone, tetrahydrofuran, ethyl acetate and dimethylacetamide(DMAc) are 51%, 84%, 94%, 96% and 92% respectively. The maximum flux in the methanol system is 11 L m−2 h−1 bar−1, while that in acetone, tetrahydrofuran, ethyl acetate and DMAc is 4.3 L m−2 h−1 bar−1, 6.3 L m−2 h−1 bar−1, 3.2 L m−2 h−1 bar−1, 4.9 L m−2 h−1 bar−1 and 2.1 L m−2 h−1 bar−1, respectively. It was also found that the membrane prepared by N-Phenylthiourea containing aromatic groups has lower mobility and stronger solvent resistance than that of by thiosemicarbazide.
17

Avila-Salgado, Denis Ariel, Arturo Juárez-Hernández, María Lara Banda, Arnoldo Bedolla-Jacuinde, and Francisco V. Guerra. "Effects of Nb Additions and Heat Treatments on the Microstructure, Hardness and Wear Resistance of CuNiCrSiCoTiNbx High-Entropy Alloys." Entropy 24, no. 9 (August 26, 2022): 1195. http://dx.doi.org/10.3390/e24091195.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
In this research, a set of CuNiCrSiCoTi (H-0Nb), CuNiCrSiCoTiNb0.5 (H-0.5Nb) and CuNiCrSiCoTiNb1 (H-1Nb) high-entropy alloys (HEAs) were melted in a vacuum induction furnace. The effects of Nb additions on the microstructure, hardness, and wear behavior of these HEAs (compared with a CuBe commercial alloy) in the as-cast (AC) condition, and after solution (SHT) and aging (AT) heat treatments, were investigated using X-ray diffraction, optical microscopy, and electron microscopy. A ball-on-disc configuration tribometer was used to study wear behavior. XRD and SEM results showed that an increase in Nb additions and modification by heat treatment (HT) favored the formation of BCC and FCC crystal structures (CS), dendritic regions, and the precipitation of phases that promoted microstructure refinement during solidification. Increases in hardness of HEA systems were recorded after heat treatment and Nb additions. Maximum hardness values were recorded for the H-1Nb alloy with measured increases from 107.53 HRB (AC) to 112.98 HRB, and from 1104 HV to 1230 HV (aged for 60 min). However, the increase in hardness caused by Nb additions did not contribute to wear resistance response. This can be attributed to a high distribution of precipitated phases rich in high-hardness NiSiTi and CrSi. Finally, the H-0Nb alloy exhibited the best wear resistance behavior in the aged condition of 30 min, with a material loss of 0.92 mm3.
18

Rabert, Claudia, Karla Inostroza, Silvana Bravo, Néstor Sepúlveda, and León A. Bravo. "Exploratory Study of Fatty Acid Profile in Two Filmy Ferns with Contrasting Desiccation Tolerance Reveal the Production of Very Long Chain Polyunsaturated Omega-3 Fatty Acids." Plants 9, no. 11 (October 24, 2020): 1431. http://dx.doi.org/10.3390/plants9111431.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
Lipids are fundamental components of cell membranes and play a significant role in their integrity and fluidity. Alteration in lipid composition of membranes has been reported to be a major response to abiotic environmental stresses. This work was focused on the characterization of frond lipid composition and membrane integrity during a desiccation–rehydration cycle of two filmy fern species with contrasting desiccation tolerance: Hymenophyllum caudiculatum (less tolerant) and Hymenophyllum plicatum (more tolerant). The relative water content decreased without differences between species when both filmy ferns were subjected to desiccation. However, H. plicatum reached a higher relative water content than H. caudiculatum after rehydration. Fatty acids profiles showed the presence of a very long chain polyunsaturated fatty acid during the desiccation–rehydration cycle, with eicosatrienoic acid being the most abundant. Additionally, propidium iodide permeation staining and confocal microscopy demonstrated that, following the desiccation–rehydration cycle, H. plicatum exhibited a greater membrane integrity than H. caudiculatum. The lack of some very long chain fatty acids such as C22:1n9 and C24:1n9 in this species contrasting with H. plicatum may be associated with its lower membrane stability during the desiccation–rehydration cycle. This report provides the first insight into the fatty acid composition and dynamics of the membrane integrity of filmy ferns during a desiccation–rehydration cycle. This could potentially play a role in determining the different levels of desiccation tolerance and microhabitat preferences exhibited by Hymenophyllaceae species.
19

ROSSI, Noreen F., and Haiping CHEN. "Modulation of ETB receptor-induced arginine-vasopressin secretion by N-methyl-D-aspartate (NMDA) and γ-aminobutyric acid (GABA)-dependent mechanisms in hypothalamo-neurohypophysial explants." Clinical Science 103, s2002 (September 1, 2002): 162S—166S. http://dx.doi.org/10.1042/cs103s162s.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
The endothelins (ETs) stimulate the secretion of arginine-vasopressin (AVP) in vivo and in vitro. The activation of hypothalamic ETB receptors increases AVP release, but the neurotransmitters mediating these responses are not known. In the compartmentalized hypothalamo–neurohypophysial explant model, the overall basal release of AVP was 53±17pg·h-1·PP-1 (where PP is posterior pituitary). ETB receptor activation in hypothalamic sites by 1nM IRL1620 dose-dependently increased AVP secretion, with a maximal response of 340±70% of basal·h-1·PP-1, whereas 1nM ET-1, the ETA receptor-selective agonist, inhibited AVP release to 44±8%·h-1·PP-1. Addition of MK801 along with IRL1620 inhibited AVP release to a value no different from basal (122±41%·h-1·PP-1). In contrast, 10µM DNQX [6,7-dinitroquinozaline-2,3-(1H,4H)-dione] did not block ETB receptor-induced AVP release (326±73%·h-1·PP-1), and nor did non-selective α-adrenergic receptor antagonism. The GABAA (where GABA is γ-aminobutyric acid) receptor agonist muscimol (10µM) inhibited AVP release in response to IRL1620 (127±30%·h-1·explant-1). These data suggest that AVP release induced by activation of hypothalamic ETB receptors is mediated by a hypothalamic N-methyl-D-aspartate (NMDA) receptor-mediated mechanism. In turn, the local release of GABA associated with NMDA activation may exert an inhibitory influence and dampen the AVP secretory response.
20

Delchev, V. B., and I. G. Shterev. "Crystal structure and photochemistry of 5-azacytosine: experimental and theoretical study." Журнал структурной химии 63, no. 3 (2022): 255. http://dx.doi.org/10.26902/jsc_id88688.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
The crystal structure of 5-azacytosine was proposed by the X-ray diffraction pattern of the compound and the performed Rietveld analysis. The crystal structure solutions were achieved with the simulated annealing procedure. The model molecule for the procedure was taken from the BLYP/aug-cc-pVDZ optimization of the N1(H) oxo-amino tautomer of the compound. The refined unit cell parameters are: a = 12.82916 Å, b = 9.47282 Å, c = 3.66363 Å, and space group P212121. The studied excited-state reaction paths of the H-detachment processes of two oxo-amino tautomers show a possibility for mutual phototransformation of the two oxo-amino tautomers: N1(H) and N5(H). The driven states of this photoreaction are the 1nσ* and 1πσ* excited states.
21

Lv, Xueqian, Zuming Liu, Ting Lei, Quan Li, Yake Ren, Xu Zhou, and Zejie Zhang. "Effect of Heat Treatment on Cr2Nb Phase and Properties of Spark Plasma Sintered Cu-2Cr-1Nb Alloy." Materials 13, no. 12 (June 25, 2020): 2860. http://dx.doi.org/10.3390/ma13122860.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
Achieving a good match between strength and conductivity is a challenge of the development of the high-performance Cu-Cr-Nb alloy for aerospace and fusion energy. The effect of heat treatment on Cr2Nb phase, strength and conductivity of spark plasma sintered (SPSed) Cu-2Cr-1Nb (at%) alloy was investigated. The results illustrated that Cr2Nb phase of Cu-2Cr-1Nb alloy can be regulated by heat treatment, multi-scale Cr2Nb phase with sizes of 0.10–0.50 μm, 30–100 nm and less than 30 nm was obtained, and the strength and conductivity were significantly increased after heat treatment at 500 °C for 2 h, the room temperature tensile strength and conductivity were 332 MPa and 86.7% IACS, 2.5% and 34.8% higher than those of as-SPSed alloy; the tensile strength at 700 °C was 76 MPa. Increasing heat treatment temperature and time, the tensile strength of the alloy was reduced by 1.5%, 4.3% and 12.3% after heat treatment at 500 °C, 700 °C and 950 °C for 72 h. The good match between strength and conductivity of Cu-Cr-Nb alloy was obtained by reducing the content of alloying elements (Cr and Nb) and microstructure regulation. This approach can be used to prepare structural/functional materials with excellent strength and conductivity.
22

Burnier, Laurent, Didier Le Roy, Thierry Roger, Thierry Fumeaux, François Saller, Marc Chanson, Delphine Borgel, et al. "Role of Growth Arrest-Specific Gene 6 Product (Gas6) in Severe Sepsis." Blood 108, no. 11 (November 16, 2006): 1640. http://dx.doi.org/10.1182/blood.v108.11.1640.1640.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
Abstract Gas6 binding to its cognate receptor tyrosine kinases (Tyro3, Axl and Mer) down-regulates the activation state of macrophages and thereby their production of proinflammatory cytokines induced by various stimuli. Mer activation inhibits TNF-α production by macrophages and alleviates endotoxic shock in mice. Gas6 receptors are cleaved in the extracellular domain to generate soluble receptors. Soluble receptors function as decoy receptors, thereby inhibiting the Gas6 interaction with cell-associated receptors. The aim of the study was to determine whether Gas6 pathway plays a role in sepsis in human and mice. In the first part of the study, we measured plasma levels of Gas6 and its soluble receptors sTyro3 and sAxl in 13 healthy subjects, 29 patients with severe sepsis, and 18 patients with acute non-infectious inflammatory diseases. Gas6 and sAxl concentrations were higher in septic patients than in healthy subjects or in patients with non-infectious inflammatory disease (P≤ 0.0001 for Gas6 and <0.004 for sAxl) and correlated with C-reactive protein levels (P=0.0019 for Gas6 and =0.0037 for sAxl). The sensitivity and specificity of Gas6 levels to predict fatal outcome was 83% and 88%. In the second part of the study, we investigated whether Gas6 affects cytokine production and outcome in experimental models of endotoxemia and peritonitis in Gas6+/+ and Gas6−/ − mice. Circulating levels of Gas6 after LPS 50mg/kg i.p. peaked at 1 h. (66±3ng/ml), were still elevated 4 h. later (47±1ng/ml) and returned approximately to baseline levels 8 h. after the LPS challenge (34±1ng/ml); P<0.001 for all time points versus baseline (23±1ng/ml). Cytokine (TNF-α and IL-6) production was higher in Gas6−/ − than Gas6+/+ mice after LPS 50mg/kg (TNF-α at 1 h.: 10±1ng/ml in Gas6−/ − versus 4.5±0.5ng/ml in Gas6+/+ mice, P<0.001; IL-6 at 4h.: 77±4ng/ml in Gas6+/+ versus 56±6ng/ml in Gas6−/ − mice, P=0.02). Similar data were obtained with Tyro3−/ − and Axl−/ − mice. Mortality induced by LPS 25mg/kg was 25% in Gas6+/+ versus 87% in Gas6−/ − mice (P=0.0023). In peritonitis models (cecal ligation and puncture, and i.p. injection of E. coli), plasma levels of Gas6 increased two-fold above baseline and remained elevated at least 24h. Increases of Gas6 levels were proportional to the importance of the size of the E. coli inoculum. In vitro experiments revealed that Gas6−/ − LPS-stimulated macrophages produced more TNF-α than Gas6+/+ macrophages. In conclusion, in septic patients, plasma levels of Gas6 and its cognate receptors were elevated and associated with fatal outcome. In mice, Gas6 plasma levels raised in experimental endotoxemia and sepsis models, and correlated also with sepsis severity. Thus, Gas6 and its receptors hold promise as early sepsis markers and outcome predictors, and could constitute therapeutic targets for new immunomodulating drugs.
23

Shang, Yilun. "Lower Bounds for Gaussian Estrada Index of Graphs." Symmetry 10, no. 8 (August 7, 2018): 325. http://dx.doi.org/10.3390/sym10080325.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
Suppose that G is a graph over n vertices. G has n eigenvalues (of adjacency matrix) represented by λ1,λ2,⋯,λn. The Gaussian Estrada index, denoted by H(G) (Estrada et al., Chaos 27(2017) 023109), can be defined as H(G)=∑i=1ne-λi2. Gaussian Estrada index underlines the eigenvalues close to zero, which plays an important role in chemistry reactions, such as molecular stability and molecular magnetic properties. In a network of particles governed by quantum mechanics, this graph-theoretic index is known to account for the information encoded in the eigenvalues of the Hamiltonian near zero by folding the graph spectrum. In this paper, we establish some new lower bounds for H(G) in terms of the number of vertices, the number of edges, as well as the first Zagreb index.
24

Thaker, Pallavi, Namrata Mahajan, Malay B. Mukherjee, and Roshan B. Colah. "Molecular Heterogeneity of Hb H Disease in India." Thalassemia Reports 12, no. 3 (July 6, 2022): 73–84. http://dx.doi.org/10.3390/thalassrep12030012.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
Alpha thalassemia is an autosomal recessive disorder caused by large deletions and/or point mutations in the α- globin genes. Hemoglobin H (Hb H) disease is most frequently due to deletion of three of the four α globin genes associated with variable clinical severity depending on the genotype. There are few reports on Hb H disease in Indians where genotyping has been done and we have reviewed the molecular and clinical heterogeneity of these cases. An electronic search for relevant articles was conducted using two journal databases, i.e., PubMed and Science Direct using the key words “Hb H Disease”, “Hemoglobin H”, “α-thalassemia”, “mutations”, “molecular heterogeneity”, “case reports” and “India”. This review was performed based on preferred reporting items for the systematic review and meta-analysis protocols (PRISMA-P) guidelines. The molecular spectrum of Hb H disease in Indians includes the most common [-α3.7, -α4.2, --SA, Poly A (AATAAA→AATA--), Hb Sallanches], rare [--SEA, --MED, IVS 1nt 1 (G→A), Hb Koya Dora, Hb Sun Prairie], very rare [Hb Iberia, Hb Seal Rock, Hb Zürich-Albisrieden] and novel [Codon 76 (+T) and --Kol] α-globin gene mutations inherited largely as compound heterozygotes with considerable clinical variability. The molecular diagnosis of Hb H disease is important for genetic counseling and management.
25

Kobayashi, H., M. Tomita, M. Ukiana, H. Mizuno, Y. Ueki, T. Yotsuji, and J. F. Konopka. "Development of the H-7100 Tem and its Computer System." Proceedings, annual meeting, Electron Microscopy Society of America 48, no. 1 (August 12, 1990): 156–57. http://dx.doi.org/10.1017/s0424820100179531.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
Built-in TV-systems for TEM image processing and storage are becoming popular in the recent TEM instrumentation. We have completed the development of the H-7100 which has greater expanding capability than the conventional instruments. The H-7100 has been designed around the computer controlled electronics of the H-7000. The new H-7100 electronics is accessible from an external computer including the specimen stage control. When it is coupled with an EDX spectrometer, an automated microanalysis is performed.Fig.l is a system diagram of the specimen stage. The rotation of the DC motor is converted to linear movement by transmission gears and a linear actuator. The linear motion is used to drive the specimen stage. The stage traverse is detected and regulated by numbers of pulse generated by a rotary encoder which is connected to the DC motor. The smallest traverse step of 1nm is available. The pulse signal of the rotary encoder is processed by a computer together with the working magnification to determine the optimum stage traverse. This design allows operator to perform both the low and high magnification work with maximum convenience and comfort. Further, specimen position memory, automatic tracking of the stage traverse and automatic return to a zero position have been incorporated.
26

Fernandez, A. I., B. Cantabrana, and A. Hidalgo. "Effects of Phorbol 12,13-Dibutyrate and H-7 1n Extravascular Smooth Muscle Contraction." Pharmacology 47, no. 3 (1993): 152–57. http://dx.doi.org/10.1159/000139092.

Full text
APA, Harvard, Vancouver, ISO, and other styles
27

Sübütay, Halit, and İlyas Şavklıyıldız. "Effect of High-Energy Ball Milling in Ternary Material System of (Mg-Sn-Na)." Crystals 13, no. 8 (August 9, 2023): 1230. http://dx.doi.org/10.3390/cryst13081230.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
In this study, the nature of the ball-milling mechanism in a ternary materials system (Mg-6Sn-1Na) is investigated for proper mechanical alloying. An identical powder mixture for this material system is exposed to different milling durations for a suitable mixture. First, the platelet structure formation is observed on particles with increasing milling duration, mainly formed in <200> direction of the hexagonal crystal structure of the Mg matrix. Then, the flake structure with texture formation is broken into smaller spherical particles with further ball milling up to 12 h. According to EDS analysis, the secondary phases in the Mg matrix are homogenously distributed with a 12-h milling duration which advises a proper mixture in this material system. The solid solution formation is triggered with an 8-h milling duration according to XRD analysis on 101 reflections. Conventional sintering is performed at 350 °C in 2 h for each sample. In bulk samples, XRD data reveal that secondary phases (Mg2Sn) with island-like structures are formed on the Mg matrix for a milling duration of up to 8 h. These bigger secondary phases are mainly constituted as Mg2Sn intermetallic forms, which have a negative effect on physical and mechanical properties due to a mismatch in the grain boundary formation. However, the homogenous distribution of secondary phases with a smaller particle size distribution, acquired with 12 h milling time, provides the highest density, modulus of elasticity, and hardness values for this ternary materials system. The ternary materials produced with the 12-h ball-milling process provide an improvement of about 117% in hardness value compared with the cast form.
28

Rubbo, Marcio, and Leandro A. Silva. "Filtering-Based Instance Selection Method for Overlapping Problem in Imbalanced Datasets." J 4, no. 3 (July 9, 2021): 308–27. http://dx.doi.org/10.3390/j4030024.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
The overlapping problem occurs when a region of the dimensional data space is shared in a similar proportion by different classes. It has an impact on a classifier’s performance due to the difficulty in correctly separating the classes. Further, an imbalanced dataset consists of a situation in which one class has more instances than another, and this is another aspect that impacts a classifier’s performance. In general, these two problems are treated separately. On the other hand, Prototype Selection (PS) approaches are employed as strategies for selecting appropriate instances from a dataset by filtering redundant and noise data, which can cause misclassification performance. In this paper, we introduce Filtering-based Instance Selection (FIS), using as a base the Self-Organizing Maps Neural Network (SOM) and information entropy. In this sense, SOM is trained with a dataset, and, then, the instances of the training set are mapped to the nearest prototype (SOM neurons). An analysis with entropy is conducted in each prototype region. From a threshold, we propose three decision methods: filtering the majority class (H-FIS (High Filter IS)), the minority class (L-FIS (Low Filter IS)), and both classes (B-FIS). The experiments using artificial and real dataset showed that the methods proposed in combination with 1NN improved the accuracy, F-Score, and G-mean values when compared with the 1NN classifier without the filter methods. The FIS approach is also compatible with the approaches mentioned in the relevant literature.
29

Cruzado, Josep M., Joan Torras, Marta Riera, Immaculada Herrero, Miguel Hueso, Luís Espinosa, Enric Condom, et al. "Influence of nephron mass in development of chronic renal failure after prolonged warm renal ischemia." American Journal of Physiology-Renal Physiology 279, no. 2 (August 1, 2000): F259—F269. http://dx.doi.org/10.1152/ajprenal.2000.279.2.f259.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
The present study examined the long-term consequences of warm renal ischemia (WRI) with or without renal ablation. Male Sprague-Dawley rats (250–300 g) were subjected to 60 min of complete WRI by pedicle clamping and then followed for 52 wk. Animals were organized into four groups: rats in which both kidneys were subjected to warm ischemia (2WIK); rats with left WRI and right nephrectomy (1WIK); uninephrectomized rats with a left nonischemic kidney (1NK); and sham-operated rats (2NK). Additional animals were studied at 24 h, 7 days, and 16 and 32 wk. In the first week after WRI, rats from the 2WIK and 1WIK groups displayed a similar degree of acute renal damage. After recovering from acute renal failure, 1WIK rats developed progressive and severe proteinuria, whereas it was mild in the 2WIK group, as well as in the 1NK and 2NK groups. Only animals from the 1WIK group developed severe chronic renal failure, glomerulosclerosis, interstitial fibrosis, and upregulation of transforming growth factor-β1 (TGF-β1) gene, which was associated with increased TGF-β1 protein expression in tubular epithelial cells, arterioles, and in areas of mononuclear interstitial cell infiltrate. On the contrary, long-term renal TGF-β1 expression, function, and histology were similar in 2WIK and 2NK rats. The present study shows that prolonged bilateral WRI, when both kidneys are retained in place, induces very mild long-term renal lesions as opposed to the severe renal scarring observed when WRI is combined with contralateral nephrectomy.
30

Esteves, L. V., F. Z. Brandão, R. C. Cruz, J. M. G. Souza, E. Oba, O. Facó, and J. F. Fonseca. "Reproductive parameters of dairy goats submitted to estrus synchronization with prostaglandin F2α associated or not to hCG at estrous onset." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 65, no. 6 (December 2013): 1585–92. http://dx.doi.org/10.1590/s0102-09352013000600001.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
The objective of this study was to evaluate the efficiency of two doses of PGF associated or not to hCG on the associated reproductive parameters in dairy goats. A total of 29 goats received two doses of 30µg d-cloprostenol latero-vulvar at a 10 day intervals (Day 1 and Day 10). The does were allocated according to body weight and body condition score into two treatments, to receive hCG (250IU) or saline at estrus onset. After the second dose of PGF, estrus was monitored and ultrasound exams were performed twice daily. All does were inseminated 16h after estrus onset. Blood collection was performed every day for progesterone assay. The use of hCG at estrus onset did not affect any studied parameter and therefore the data were pooled. Estrous response rate was similar (P>0.05) after the first (75.9%, 22/29) and the second dose of PGF (79.3%, 23/29). The interval between the administration of PGF and estrus onset was greater (P<0.05) after Day 1 (75.8±53.9h) than Day 10 (47.7±10.1 h). Estrus duration was superior (P < 0.05) after Day 1 (35.4±15.9h) to Day 10 (26.8±15.0h). Ovulation rate was 79.3% (23/29) after the second dose of PGF. No differences (P>0.05) between both experimental groups were detected in the following parameters, averaging: the interval from the second dose administration to the ovulation (86.6±11.4h), interval from estrus to ovulation (39.9±12.3 h), diameter of largest follicle (7.2±1.4) and number of ovulations (1.8±0.6). At Day 1, 52.4% (11/21) of does presented progesterone concentrations <1ng/mL. At Day 10, 100% of the animals presented concentrations >1ng/mL. The results of the present study indicate that estrus can be efficiently synchronized in dairy goats with the use of two doses of PGF at a 10 day interval. Further research should be done evaluating hCG use in different doses or moments of administration.
31

Nadal-Quirós, Mónica, Leon C. Moore, and Mariano Marcano. "Parameter estimation for mathematical models of a nongastric H+(Na+)-K+(NH4+)-ATPase." American Journal of Physiology-Renal Physiology 309, no. 5 (September 1, 2015): F434—F446. http://dx.doi.org/10.1152/ajprenal.00539.2014.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
The role of nongastric H+-K+-ATPase (HKA) in ion homeostasis of macula densa (MD) cells is an open question. To begin to explore this issue, we developed two mathematical models that describe ion fluxes through a nongastric HKA. One model assumes a 1H+:1K+-per-ATP stoichiometry; the other assumes a 2H+:2K+-per-ATP stoichiometry. Both models include Na+ and NH4+ competitive binding with H+ and K+, respectively, a characteristic observed in vitro and in situ. Model rate constants were obtained by minimizing the distance between model and experimental outcomes. Both 1H+(1Na+):1K+(1NH4+)-per-ATP and 2H+(2Na+):2K+(2NH4+)-per-ATP models fit the experimental data well. Using both models, we simulated ion net fluxes as a function of cytosolic or luminal ion concentrations typical for the cortical thick ascending limb and MD region. We observed that 1) K+ and NH4+ flowed in the lumen-to-cytosol direction, 2) there was competitive behavior between luminal K+ and NH4+ and between cytosolic Na+ and H+, 3) ion fluxes were highly sensitive to changes in cytosolic Na+ or H+ concentrations, and 4) the transporter does mostly Na+/K+ exchange under physiological conditions. These results support the concept that nongastric HKA may contribute to Na+ and pH homeostasis in MD cells. Furthermore, in both models, H+ flux reversed at a luminal pH that was <5.6. Such reversal led to Na+/H+ exchange for a luminal pH of <2 and 4 in the 1:1-per-ATP and 2:2-per-ATP models, respectively. This suggests a novel role of nongastric HKA in cell Na+ homeostasis in the more acidic regions of the renal tubules.
32

Cui, Ya Peng, Zi Yong Chen, Xiao Zhao Ma, Ying Ying Liu, Zhi Lei Xiang, and Li Hua Chai. "Microstructures and Mechanical Properties of a New Type of High Temperature Titanium Alloy." Materials Science Forum 993 (May 2020): 208–16. http://dx.doi.org/10.4028/www.scientific.net/msf.993.208.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
The microstructures and mechanical properties of a new type near α high temperature titanium alloy Ti-6.5Al-2.5Sn-9Zr-0.5Mo-0.25Si-1Nb-1W-0.3Re (wt. %) (denoted as TA6.5) were investigated. It was observed that the microstructure of forged TA6.5 mainly consisted of deformed lamellar α phase, small amount of equiaxed α phase, and residual β phase, exhibiting high strength and comparatively low elongation. Three different heat treatments processes were performed on forged TA6.5. The results showed that all heat treated alloys displayed high tensile strengths, and the values of strength parameters were almost unchanged with the increasing solution temperature, ascribing to the combination effects of decreasing primary α phase and increasing contents and widths of secondary α phase and lamellas. The tensile elongations of heat treated alloys tested at 650 °C decreased slightly with the increasing solution temperature, which is due to the increased width of secondary α lamellas and the generation of coarse grain boundary α phase. TA6.5 treated in the process of 990 °C/1 h/AC+700 °C/4 h/AC exhibited excellent comprehensive mechanical properties, i.e. the ultimate tensile strength of 829 MPa, yield strength of 707 MPa and elongation of 18.73% respectively.
33

CHANDRA, VIKASH, ASHISH MISHRA, and G. TARU SHARMA. "Effect of growth factors (epidermal growth factor, platelet derived growth factor, and insulin-like growth factor-1) on buffalo embryos produced in vitro." Indian Journal of Animal Sciences 82, no. 12 (December 13, 2012): 1510–14. http://dx.doi.org/10.56093/ijans.v82i12.25666.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
The present study examined effect of epidermal growth factor (EGF) on buffalo oocytes maturation and its subsequent effect on embryo development when embryos cultured in media supplemented either with insulin-like growth factor-1 (IGF-1) or/and platelet-derived growth factor (PDGF). Slaughterhouse derived excellent to good quality oocytes were matured for 24 h in TCM-199 supplemented with epidermal growth factor (EGF, 20ng/ml) and without EGF (control), 10% follicular fluid and 10% fetal bovine serum. Matured oocytes were fertilized with frozen buffalo bull semen. Presumptive zygotes were divided and cultured in 4 groups each: Group 1 (control, containing mSOF+ ß-mercaptoethanol, 100µM), group 2 (control + IGF-1, 100ng/ml), group 3 (control+ PDGF, 1ng/ml) and group 4 (control+ IGF-1 +PDGF). Maturation rate was higher in EGF supplemented group compared to control group (85.7% vs 67.5%). Cleavage rate was also higher in EGF supplemented groups. Overall developmental rate of in vitro produced embryos was significantly higher in EGF supplemented group except in PDGF supplemented groups. PDGF supplemented group showed highest cleavage when oocytes matured with EGF (42.0% and 45.5%) but was not able to convert proportionate embryos to blastocyst (15.9% and 18.5%) while IGF-1 supplemented group showed highest percentage of blastocysts (29.7%). These results indicated that addition of IGF-1 (100ng/ml) improved the cleavage and blastocyst production rate, whereas PDGF (1ng/ml) though improved cleavage significantly but showed comparatively low blastocyst production rate. It can be concluded that oocytes matured in EGF (20ng/ml) and subsequently cultured in IGF-1 (100ng/ml) supplemented media have greater embryonic developmental potential.
34

Hasbullah, N. I., Mat Zain Mazatulikhma, and N. Kamarulzaman. "Nanotoxicity of Magnesium Oxide on Human Neuroblastoma SH-SY5Y Cell Lines." Advanced Materials Research 667 (March 2013): 160–64. http://dx.doi.org/10.4028/www.scientific.net/amr.667.160.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
The use of magnesium oxide (MgO) nanoparticles in industrial applications has been raised over the last decade. However, there is limited toxicology information available regarding the effects of MgO nanoparticles. In this study, cytotoxicity and neurotoxicity of this nanoparticle on SH-SY5Y cell lines was investigated. In order to assess the cytotoxicity effect, SH-SY5Y cells were exposed to three different types of MgO nanoparticles (MgO 5, MgO 10 and MgO 24) for 24, 48 and 72 h. The concentration of nanoparticles ranges from 1nM to 1mM. Cell viability was determined by MTS assay. Neurotoxicity test was performed to determine the effects of MgO nanoparticles on human neural cells. Results indicated that MgO nanoparticles are not toxic to both undifferentiated and differentiated SH-SY5Y cells. With further exploration, the safety and health concern regarding exposure of MgO nanoparticles can be verified since the increasing of using this nanoparticle in industry over the time.
35

Ketchum, Jaclyn N., Lacey K. Quail, Kaitlin M. Epperson, Chloey Guy, Jerica J. J. Rich, Saulo Menegatti Zoca, Adalaide Kline, et al. "292 Evaluation of two Beef cow Fixed-Time AI Protocols That Utilize pre-Synchronization." Journal of Animal Science 100, Supplement_3 (September 21, 2022): 139–40. http://dx.doi.org/10.1093/jas/skac247.257.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
Abstract Pre-synchronization has been evaluated as a method to improve synchrony of ovulatory follicles before fixed-time AI (FTAI). The objective was to compare FTAI results in beef cows from two protocols that utilize pre-synchronization. Blood samples were collected on d-14 (d0=CIDR removal) to determine progesterone concentration at the start of synchronization (P4start: ≥1ng/mL=high, &lt; 1ng/mL=low). In a subset (n=1,032), an additional blood sample was taken between d-21 and -29 to determine cyclicity. Cows (n=1,119), from 21 herds, were grouped by days postpartum and age and randomly assigned to one of two protocols. Cows assigned to the PG 6-day CIDR protocol (PG6d) received prostaglandin F2α (PG) on d-9, CIDR insertion and GnRH on d-6, and CIDR removal and PG on d0. Cows assigned to the 7&7 Synch protocol (7&7) were administered PG and CIDR insertion on d-14, GnRH on d-7, CIDR removal and PG on d0. For both protocols, FTAI occurred coincident with GnRH 66 h after second PG. Pregnancy was determined by transrectal ultrasonography 30-40 d following FTAI. The GLIMMIX procedure of SAS (9.4) was used to detect differences in estrus response and pregnancy success with herd included as a random variable. Estrus response (0 to 66 h) was influenced by treatment (P&lt; 0.01; PG6d=60±5% and 7&7=74±4%), Body Condition Score (P&lt; 0.01), cycling status (P=0.03), P4start (P&lt; 0.01), and a P4start by treatment interaction (P&lt; 0.001; PG6d-highP4=62±6%, PG6d-lowP4=58±6%, 7&7-highP4=84±3%, 7&7-lowP4=60±6%). Pregnancy success was influenced by estrus expression (P&lt; 0.01; estrus=38±4% and no estrus=62±6%), and a treatment by P4start interaction (P=0.04; PG6d-highP4=58±5%, PG6d-lowP4=39±7%, 7&7-highP4=49±5%, 7&7-lowP4=55±8%) but was not influenced by treatment (P=0.45; PG6d=49±4% and 7&7=52±4%). In conclusion, effectiveness of pre-synchronization method depends on a cows’ physiological status at the beginning of the protocol. The 7&7 protocol increased estrus response compared to PG6d, but there was no difference in pregnancy success.
36

Xiao, Shen, Delbert G. Gillespie, Christine Baylis, and Edwin K. Jackson. "Estradiol and Its Metabolites Differentially Induce NO Synthesis by Human Glomerular Endothelial Cells and Inhibit Glomerular Mesangial Cell Growth." Hypertension 36, suppl_1 (October 2000): 710. http://dx.doi.org/10.1161/hyp.36.suppl_1.710-a.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
P93 Reduced NO synthesis by glomerular endothelial cells (GECs) and increased proliferation of glomerular mesangial cells (GMCs) is associated with glomerular remodeling process leading to glomerosclerosis. Moreover, estradiol (E) slows the progression of renal disease. Because E induces NO synthesis and E metabolites are as potent as E in inhibiting growth of vascular smooth muscle cells, which are phenotypically similar to GMCs, we investigated whether E and its major endogenous metabolites (2-hydroxyestradiol[2OHE] and 2-methoxyestradiol [2MeOE])inhibit growth of GMCs and induce basal NO synthesis by GECs. E and its metabolites (1nM-10μM)inhibited serum (2.5%)-induced DNA synthesis, cell number and collagen synthesis in human GMCs concentration-dependently,and with the order of potency being 2MeOE > 2OHE > E. ICI182780, an estrogen receptor antagonist (100μM) blocked the growth inhibitory effects of E, but not 2OHE and 2MeOE. Treatment with E, but not 2OHE and 2MeOE, induced NO synthesis (P<.05; assayed by the formation of 3 H-L-citrulline from 3 H-L-arginine) in human GECs, and these effects were blocked by ICI182780 and L-NMA (NO synthesis inhibitor).In conclusion, E may protect glomerosclerosis by inducing NO synthesis via an estrogen receptor-dependent mechanism and via conversion to 2OHE and 2MeOE, which inhibit GMC proliferation independently of the estrogen receptor.
37

Libera, Ondřej, Patricie Halodová, Petra Gávelová, and Jakub Krejčí. "NANOINDENTATION OF HYDROGEN ENRICHED Zr-1Nb ZIRCONIUM ALLOY NUCLEAR FUEL CLADDINGS." Acta Polytechnica CTU Proceedings 27 (June 11, 2020): 155–59. http://dx.doi.org/10.14311/app.2020.27.0155.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
Zirconium alloys are being commonly used as a material of choice for nuclear fuel claddings in water cooled nuclear reactors for decades due to their good corrosion resistance and low neutron absorption. However, the increasing operation conditions of next generation nuclear reactors (Gen-V) in terms of higher temperatures, pressures and higher neutron flux requires evaluation of further Zr cladding usability. The embrittlement of Zr claddings due to hydrogen pickup from reactor coolant is one of the issues for its potential use in Gen-IV reactors. Nanoindentation is an effective tool for analysis of the change of mechanical properties of hydrogen enriched Zr claddings from localised material volume. Zirconium alloy Zr-1Nb (E110) with experimentally induced hydrides was analysed by the means of nanoindentation. Zirconium hydrides were formed in the material after exposure in high temperature water autoclave. The optimized methodology of surface preparation suitable for nanoindentation is described and the resulting surface quality is discussed. The nanoindentation measurements were performed as an array of 10x10 indents across areas with hydrides. Depth dependent hardness and reduced modulus values measured by nanoindentation were compared between the material with no hydrogen content, low hydrogen content (127 ppm H) and high hydrogen content (397 ppm H). Complementary microhardness measurements at HV 0.1 were performed on all materials for bulk material hardness comparison.
38

Nandipati, K. R., Arun Kumar Kanakati, H. Singh, and S. Mahapatra. "Controlled intramolecular H-transfer in malonaldehyde in the electronic ground state mediated through the conical intersection of 1nπ* and 1ππ* excited electronic states." Physical Chemistry Chemical Physics 21, no. 36 (2019): 20018–30. http://dx.doi.org/10.1039/c9cp03762d.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
We report photo-isomerization of malonaldehyde in its electronic ground state (S0), mediated by coupled 1nπ*(S1)–1ππ*(S2) excited electronic states, accomplished with the aid of optimally designed ultraviolet (UV)-laser pulses.
39

Prieto Vidal, Natalia, Oludoyin Adeseun Adigun, Thu Pham, Abira Mumtaz, Charles Manful, Grace Callahan, Peter Stewart, Dwayne Keough, and Raymond Thomas. "The Effects of Cold Saponification on the Unsaponified Fatty Acid Composition and Sensory Perception of Commercial Natural Herbal Soaps." Molecules 23, no. 9 (September 14, 2018): 2356. http://dx.doi.org/10.3390/molecules23092356.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
Saponification is the process in which triglycerides are combined with a strong base to form fatty acid metal salts during the soap-making process. The distribution of unsaturated and saturated fatty acid determines the hardness, aroma, cleansing, lather, and moisturizing abilities of soaps. Plant extracts, such as rosemary, vegetable, and essential oils are frequently added to soaps to enhance quality and sensory appeal. Three natural soaps were formulated using cold saponification to produce a base or control bar (BB), hibiscus rosehip bar (H), and a forest grove bar (FG). Rosemary extract (R) or essential oil (A) blends were added as additives to each formulation prior to curing to evaluate the effects of natural plant additives on the lipid composition and sensory characteristics of these natural herbal soaps. A total of seven natural soaps, three without additives (BB, H, FG) and four with additives (BBR, HA, FGR, FGA), were manufactured and studied. The majority (86–99%) of the polyunsaturated fatty acids (5.0–7.0 µg/mg) remained unsaponified in the manufactured natural soaps regardless of feedstock used. Principal component analysis (PCA) analyses showed the unsaponifiable fatty acids were different in the hibiscus bar compared to the other bars. There was a very strong correlation between the content of unsaponified C18:3n3 and C18:1n9 in all natural soaps. These results indicate that unsaponified fatty acids are important contributors to the quality and overall sensory perception and preference of natural herbal soaps following manufacturing by cold saponification.
40

Saeed, Osama A., Umar M. Sani, Awis Q. Sazili, Henny Akit, Abdul R. Alimon, and Anjas A. Samsudin. "Profiling of Fatty Acids and Rumen Ecosystem of Sheep Fed on a Palm Kernel Cake-Based Diet Substituted with Corn." Agriculture 13, no. 3 (March 9, 2023): 643. http://dx.doi.org/10.3390/agriculture13030643.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
The purpose of this study was to analyze the effects of corn substitution on the rumen functions and fatty acid profile of Dorper lambs fed a diet based on palm kernel cake (PKC). Corn was replaced with PKC basal diet at the following levels: C0% = (0% corn + 75.3% PKC), C1% = (5% corn + 70.3% PKC) and C2% = (10% corn + 65.3% PKC) of diet. The rumen fermentation was carried out in vitro, and feeding trials were in vivo. Twenty-seven lambs were used to determine gastrointestinal tract content and rumen fluid fatty acid. Rumen liquor was obtained from four fistulae Dorper sheep and incubated with 200 mg of each treatment for 24 and 72 h. In vitro organic matter digestibility (IVOMD), in vitro dry matter digestibility (IVDMD), volatile fatty acids (VFA), methane estimation (CH4), rumen microbial population and fatty acid biohydrogenation were determined. The results of the in vitro study showed there were no significant differences in IVDMD, IVOMD, NH3-N, pH and VFA at 72 h. Higher significant CH4 production was observed in C0% when compared with C1% and C2%. Microbial population did not differ significantly between treatment groups. The rates of biohydrogenation were not affected by corn substitution, although a significant difference was observed in C18:1n9 (in vitro) and C18:1 t-11 (in vivo). In conclusion, the present study indicated that the corn substitution in the PKC diets maintained fermentation characteristics with an increase in unsaturated fatty acids in the rumen.
41

Callejas, S., G. Uslenghi, J. Larghi, and J. Cabodevila. "Comparación de dos protocolos para sincronizar ovulación e implementar inseminación artificial en vaquillonas." Revista Veterinaria 25, no. 2 (October 7, 2016): 100. http://dx.doi.org/10.30972/vet.252502.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
Se efectuaron dos experimentos (EI y EII) en vaquillonas Bos taurus de 20-24 meses de edad y 3-3,5 de condición corporal (escala 1 a 5). El objetivo fue comparar dos protocolos de sincronización de la ovulación (PSO), utilizando dispositivos intravaginales con progesterona (DISP) combinados con cipionato de estradiol (CPE) administrado al momento de retirar el DISP o benzoato de estradiol (BE) 24 h más tarde. En el día 0, las vaquillonas (EI, n=16; EII, n=173) recibieron un DISP (1 g de progesterona) más 2 mg BE; en el día 8 se retiró el DISP, se administraron 0,150 mg de D-Cloprostenol y se aplicó, a sendos PSO, una inyección de 1 mg de CPE en dicho momento o 1 mg de BE 24 h más tarde. En EI, se efectuaron ecografías (días 0, 8 y 9 y desde este último momento cada 12 h hasta el día 11) y muestreos sanguíneos para determinar progesterona plasmática (P4; días 8, 9, 10, 11 y 21); se determinó porcentaje de vaquillonas con cuerpo lúteo (días 0 y 8), los diámetros de los folículos dominante (FD, día 8) y ovulatorio. En EII, se realizó IATF (día 10) y se determinó preñez (día 35). Los análisis estadísticos se realizaron por SAS. Los diámetros del FD (13,1±2,4 mm) y ovulatorio (15,4±2,2 mm) y el intervalo retiro DISP-ovulación (65,3±5,3 h) no difirieron entre PSO (p>0,05); se observó un efecto del día sobre el nivel de P4 (p<0,05), no así del PSO o interacción PSO x día (p>0,05), el nivel de P4 al día 8 (4,6±4,4 ng/ml) disminuyó a valores <1ng/ml post retiro del DISP. La preñez fue similar entre PSO (60,7%; p>0,05). Se concluye que en vaquillonas Bos taurus, ambos PSO generan similares cambios ováricos, variaciones en el nivel de P4 y porcentajes de preñez.
42

Read, Mike. "Wild Flowers of the Falkland IslandsT. H. Davies and J. H. McAdam Bluntisham Books, Huntingdon, 48pp., SB £3.50 plus £1.00 postage from Dr Kate Thompson, East Mains Cottage, Tullibardine, Auchterarder, Perthshire PH3 1NU, UK." Oryx 24, no. 4 (October 1990): 232. http://dx.doi.org/10.1017/s0030605300035018.

Full text
APA, Harvard, Vancouver, ISO, and other styles
43

Chien, Dang Tran, and Pham Duy Long. "Effect of Annealing Temperature on the Structure, optical and Electronic Properties of \(\text{TiO}_{2}\) Made by Thermal Treatment of \(\text{Ti}\)." Communications in Physics 24, no. 2 (July 18, 2014): 155. http://dx.doi.org/10.15625/0868-3166/24/2/3702.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
In this work, TiO\(_{2}\) nanocrystalline thin films were obtained through evaporating Ti films by Electron Beam Deposition (EBD) followed by thermal treatment. The deposition speed of Ti thin fims was carried out at 0.15 nm/s and 1 nm/s. The results show that after annealing at 450\(^\circ\)C for 8 h, the obtained TiO\(_{2}\) thin films have nanoparticle structure with grain size of 20 nm for the Ti thin film deposited at the rate of 1nm/s, whereas at the a deposition rate of 0.15 nm/s, the TiO\(_{2}\) has a nanorod structure with the rod length of 300 -- 400 nm. At 700\(^\circ\)C for 8 h, the rutile phase was formed. At annealing temperature of 450\(^\circ\)C, all the samples are close to the stress free TiO\(_{2}\). The band gap of TiO\(_{2}\) thin films decreased with annealing temperature in both doposition rate of Ti thin films. The response of the films annealed at 450\(^\circ\)C presented a faster rise and fall in photocurrent under UV illumination on and off interval. Nanoporous structure TiO\(_{2}\) shows photoelectronic property better than that of nanorod structure. The obtained TiO\(_{2}\) films were characterized by X-ray diffraction (XRD) and a field emission scanning electron microscope (FE-SEM). The TiO\(_{2}\) films were used in a photo-electrochemical (PEC) cell as a working electrode and a platinum electrode as a counter electrode. The electrolyte solution contains 1 M KCl and 0.1 M Na\(_{2}\)S.
44

Nandi, Shishir Kumar, Afrina Yeasmin Suma, Aminur Rashid, Muhammad Anamul Kabir, Khang Wen Goh, Zulhisyam Abdul Kari, Hien Van Doan, Nik Nur Azwanida Zakaria, Martina Irwan Khoo, and Lee Seong Wei. "The Potential of Fermented Water Spinach Meal as a Fish Meal Replacement and the Impacts on Growth Performance, Reproduction, Blood Biochemistry and Gut Morphology of Female Stinging Catfish (Heteropneustes fossilis)." Life 13, no. 1 (January 6, 2023): 176. http://dx.doi.org/10.3390/life13010176.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
The identification and development of a new plant-based feed ingredient as an alternative protein source to FM have gained the interest of the aquafeed industrial players. Therefore, this study aimed to investigate the physical, biochemical, and bacteriological properties of dietary FWM and the impacts on the growth and reproductive performances of farmed female stinging catfish, H. fossilis broodstock. Five experimental diets were formulated with different FWM inclusion (0, 25, 50, 75, and 100%). Fatty acid profiles such as 4:0, 10:0, 20:0, 21:0, 22:0, 24:0, 20:1n9, 18:3n6, 20:3n6, 20:4n6, and 22:6n3 were found in higher levels in FWM compared to the water spinach meal (WM). Meanwhile, there were no significant differences in the physical properties of the FWM experimental diets (p > 0.05). Furthermore, the experimental feed with 0, 25, 50, and 75% FWM were more palatable to the broodstock than 100% FWM. The number of total bacteria (TB) and lactic acid bacteria (LAB) in catfish diets exhibited a rising trend with an increase in FWM, while 50% of FWM-fed fish intestines had a significantly (p < 0.05) higher TB and LAB than other treatment groups. The growth, feed utilization, and reproductive variables of H. fossilis were significantly (p < 0.05) influenced by FWM inclusion at various levels. Moreover, the significantly (p < 0.05) highest oocytes weight, fertilization, egg ripeness, and ovipositor diameter were observed in the treatment of 50% FWM diet treatment group. In addition, the spawning response was 100% in all treatments except for the control group (66.67%). Significant differences (p < 0.05) were found in the hematological and serum biochemical indices in most treatment groups. In addition, the histological analysis of H. fossilis midintestinal tissue indicated that the fish fed with a 50% FWM diet had an unbroken epithelial barrier with more goblet cell arrangements and a well-organized villi structure and tunica muscularis compared to other treatment groups. These outcomes suggested that FWM at 50% inclusion is an adequate protein supplement for fish feed, resulting in better growth, reproductive performance, and health of H. fossilis broodstock development.
45

Pappa, Vassiliki, F. Kontsioti, E. Liakata, S. Papageorgiou, A. Spathis, P. Tsirigotis, ED Ioannidou, et al. "Dasatinib Is An Effective Inhibitor of Proliferation and Inducer of Apoptosis in the KASUMI Cell Line Bearing the T(8;21)(q22;q22) and the N822K KIT Mutation." Blood 112, no. 11 (November 16, 2008): 5054. http://dx.doi.org/10.1182/blood.v112.11.5054.5054.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
Abstract Introduction. Within the group of core binding factor (CBF) AML, the presence of the t(8;21)(q22;q22) confers a favorable prognosis based on high complete remission rates and high survival probabilities. However within this subgroup the presence of KIT mutations and in some studies specifically mutations at codon 816 in exon 17 have been associated with inferior event free survival, relapse free survival, cumulative incidence of relapse and overall survival. Dasatinib a dual SRC/ABL kinase inhibitor is an active agent already approved for the treatment of imatinib resistant or intolerant chronic myelogenous leukemia which has shown in vitro activity against KIT exon 17 mutations including the D816 imatinib resistant mutation. The aim of the present study was the investigation of the activity of dasatinib on cell proliferation and apoptosis of leukemic cell lines with or without KIT mutations. Materials and methods. The leukemic cell lines ME-1, NB4 and KASUMI were cultured in RPMI. Following RNA extraction RT-PCR was performed for the amplification of the extracellular (exon 8,9), transmembrane/juxtamembrane (exon 10,11) and tyrosine kinase 2 domains (exon 17,18) of c-Kit.Following sequencing only the KASUMI cell line derived from a t(8;21)(q22;q22) AML was found to bear the N822K KIT mutation at exon 17, also described in patients’samples. The KASUMI, the K562 cell line bearing the t(9;22) used as a positive control and the NB4 cell line without KIT mutations used as a negative control, were subsequently cultured under the presence of dasatinib at the concentrations of 1nM, 10nM, 100nM, 500 nM. Cell proliferation, was determined at 24, 48, 72 h using the Cell Proliferation Elisa, BrDU protocol and apoptosis was determined by the method of annexin using flow cytometry at the same time points. Results The BrDU value of K562 cells at 48h without the drug was 1.046 significantly higher compared to those of cells cultured under the presence of Dasatinib at 1nM, 10nM, 100nM, 500 nM (0.6485, 0,5647, 0,4770, 0.4755 respectively) (p&lt;0.001). Similarly the BrDU value of K562 cells without the drug at 72h was 1.320 significantly higher to those under the presence of the drug at 10, 100, 500 nM (0.8137, 0.7292, 0.6637 respectively) (p&lt;0.001). The level of apoptosis was significantly induced by the drug at all concentrations at 24h(p&lt;0.001) and at the concentrations of 10nM, 100nM, 500 nM at 48h (p&lt;0.001) but not at 72h.Ôhere was no effect of the drug on the proliferation and apoptosis of the NB4 cell line. In the KASUMI cells there was a significant reduction of the BrDU values by the presence of dasatinib at the concentrations of 10nM, 100nM, 500nM at 48h (0.9517 vs 0.6462, 0.5653, 0.3467, p=0.038, 0.011, 0.002 respectively). The same was true at the concentrations of 100nM and 500nM at 72h (0.9538 vs 0.2412, 0.1907, p=0.002, 0.004 respectively). Dasatinib significantly increased the level of apoptosis of the KASUMI cells at 24h at 1nM, 10nM, 100nM (2.45 vs 1.41, 1.71, 2.18, p&lt;0.001, &lt;0.001, 0.026 respectively) At 48h dasatinib significantly increased the level of apoptosis at the concentrations of 1nM, 10nM, 100nM (0.84vs 1.03, 1.49, 2.81, p=0.02, p&lt;0.001, p&lt;0.001 respectively). At 72h there was a significant induction of apoptosis by the drug at all concentrations (0.16 vs 1.11, 1.94, 2.93, 1.88 p&lt;0.001) Conclusion. Dasatinib is an effective suppressor of proliferation and inducer of apoptosis of the KASUMI cell line with the t(8;21)(q22;q22) and the N822K KIT mutation. These encouraging results need to be confirmed on patients’ cells with the view to integrate the drug in conventional chemotherapy regimens in future clinical trials.
46

Kouchaki, Samaneh, Reza Boostani, and Fatemeh Razavipour. "FATIGUE DETECTION USING THE STRENGTH OF DOMINANT EEG SOURCE: A BEAMFORMING APPROACH." Biomedical Engineering: Applications, Basis and Communications 30, no. 03 (May 30, 2018): 1850023. http://dx.doi.org/10.4015/s1016237218500230.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
It is evident that the electroencephalogram (EEG) rhythms are slightly changed when the efficacy of mental activity declines (brain fatigue). Nonetheless, this slight change is not easily detectable by the so far suggested scalp EEG features. The goal of this paper is to propose an EEG-based biomarker, which has a congruity to the mental fatigue variation to detect the transition from non-fatigue to the fatigue mental state. The strength of the dominant EEG source, extracted by minimum variance beamformer (MVB), is proposed here as a discriminative feature to remarkably classify the two mental states. To assess the proposed scheme, EEG signals of 17 volunteers were recorded via 32 electrodes before and after taking an exhausting mental exam (3[Formula: see text]h) and the extracted EEG features were labeled as non-fatigue and fatigue, respectively. After removing the eye-blink effect, the proposed feature along with the conventional EEG features were extracted from the recorded EEGs and then applied to support vector machine (SVM) and 1-nearest neighbor (1NN) classifiers in order to differentiate these two mental states. The best result is achieved by applying the proposed feature to the SVM classifier providing 97.06% classification accuracy which is significantly ([Formula: see text]) superior to its counter parts.
47

Lawer-Yolar, Gideon, Benjamin Dawson-Andoh, and Emmanuel Atta-Obeng. "Synthesis of Biodiesel from Tall Oil Fatty Acids by Homogeneous and Heterogeneous Catalysis." Sustainable Chemistry 2, no. 1 (March 10, 2021): 206–21. http://dx.doi.org/10.3390/suschem2010012.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
This study compared the yield of biodiesel produced from tall oil fatty acids (TOFA) via (i) homogeneous catalyst (sulfuric acid) and (ii) a heterogeneous catalyst (Amberlyst® BD20, together with Ambersep BD 19 (Midcontinental Chemical Co., Olathe, KS, USA)® using a batch reactor. The effect of operation conditions including temperature, catalyst concentration, methanol: oil ratio and reaction time on esterification yield were investigated. Gas chromatographic data showed that the major fatty acids present in the TOFA are oleic acid (C18:1n9) and linoleic acid (C18:2n6). Homogenous catalysis yielded 96.76% biodiesel compared to 90.24% for heterogeneous catalysis. Optimized conditions for homogenous catalysis were at a catalyst concentration of 0.5 w/w%, 15:1 methanol: oil mass ratio at 55 °C for 60 min. FTIR results also showed that the homogeneous catalyst yielded a more complete reaction toward biodiesel production in a shorter time (60 min) compared to the heterogeneous catalyst (4.7 h). For heterogeneous catalysis, the highest yield and the lowest acid value were achieved after a second recycling because the reactants were not fully in contact with the catalyst during the first recycling. The catalyst did not show a reduction in catalytic activity even after the fourth recycling. However, the acid value was higher than that for ASTM standards for biodiesel.
48

Li, Zhi Jun, Shuang Ling Jin, Shi Min Zhang, Hua Feng Zhang, Ning Jiang, Jie Ling Cheng, Xia Shao, Ming Lin Jin, and Rui Zhang. "Influence of Surface Properties and Pore Structure of High Surface Activated Carbon on Adsorption Capacity of Dibenzothiophene." Advanced Materials Research 1061-1062 (December 2014): 244–50. http://dx.doi.org/10.4028/www.scientific.net/amr.1061-1062.244.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
Four activated carbons (ACs) with different properties were heat-treated at 600 °Cfor 3 h and the ACs before and after the treatment were characterized by nitrogen adsorption and XPS. The relationship between pore texture, surface chemistry and dibenzothiophene adsorption capacity was investigated. It is found that pore volume for the pore below 1nm and between 1.1-1.6 nm decreases and increases respectively, and mesopore volume increases after the heat treatment. The Brunauer- Emmett-Teller (BET) surface areas of the four samples remain almost the same after the treatment. The surface oxygen content decreases after the treatment. The adsorption isotherms can be better fitted by Freundlich equation than Langmuir equation, indicating that the adsorption sites on surface of the ACs is inhomogeneous. The dibenzothiophene adsorption capacity has a linear relationship with the pore volume of the pores in the range of 0.536-1.179 nm, indicating that micropore filling of dibenzothiophene is the dominant mechanism for dibenzothiophene adsorption. The adsorption capacity of dibenzothiophene for the pristine ACs is larger than that of the heat-treated ACs under the same pore volume for the pores in the range of 0.536-1.179 nm, indicating that surface oxygen functional groups favors the adsorption for dibenzothiophene.
49

Vithana, Vidushi P., Zhifang Guo, Glen B. Deacon, Anthony E. Somers, and Peter C. Junk. "RE(III) 3-Furoate Complexes: Synthesis, Structure, and Corrosion Inhibiting Properties." Molecules 27, no. 24 (December 13, 2022): 8836. http://dx.doi.org/10.3390/molecules27248836.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
In this study, two types of Rare Earth (RE) 3-furoate complexes were synthesized by metathesis reactions between RE chlorides or nitrates and preformed sodium 3-furoate. Two different structural motifs were identified as Type 1RE and Type 2RE. The Type 1RE monometallic complexes form 2D polymeric networks with the composition [RE(3fur)3(H2O)2]n (1RE = 1La, 1Ce, 1Pr, 1Nd, 1Gd, 1Dy, 1Ho, 1Y; 3furH = 3-furoic acid) while Type 2RE bimetallic complexes form 3D polymeric systems [NaRE(3fur)4]n (2RE = 2Ho, 2Y, 2Er, 2Yb, 2Lu). The stoichiometric mole ratio used (RE: Na(3fur) = 1:3 or 1:4) in the metathesis reaction determines whether 1RE or 2RE (RE = Ho or Y) is formed, but 2RE (RE = Er, Yb, Lu) were obtained regardless of the ratio. The corrosion inhibition behaviour of the compounds has been examined using immersion studies and electrochemical measurements on AS1020 mild steel surfaces by a 0.01 M NaCl medium. Immersion test results revealed that [Y(3fur)3(H2O)2]n has the highest corrosion inhibition capability with 90% resistance after 168 h of immersion. Potentiodynamic polarisation (PP) measurements also indicate the dominant behaviour of the 1Y compound, and the PP curves show that these rare earth carboxylate compounds act predominantly as anodic inhibitors.
50

Duus, Karen M., Eric D. Miller, Jonathan A. Smith, Grigoriy I. Kovalev, and Lishan Su. "Separation of Human Immunodeficiency Virus Type 1 Replication from nef-Mediated Pathogenesis in the Human Thymus." Journal of Virology 75, no. 8 (April 15, 2001): 3916–24. http://dx.doi.org/10.1128/jvi.75.8.3916-3924.2001.

Full text
APA, Harvard, Vancouver, ISO, and other styles
Abstract:
ABSTRACT Human immunodeficiency virus type 1 (HIV-1) is frequently attenuated after long-term culture in vitro. The attenuation process probably involves mutations of functions required for replication and pathogenicity in vivo. Analysis of attenuated HIV-1 for replication and pathogenicity in vivo will help to define these functions. In this study, we examined the pathogenicity of an attenuated HIV-1 isolate in a laboratory worker accidentally exposed to a laboratory-adapted HIV-1 isolate. Using heterochimeric SCID-hu Thy/Liv mice as an in vivo model, we previously defined HIV-1 env determinants (HXB/LW) that reverted to replicate in vivo (L. Su, H. Kaneshima, M. L. Bonyhadi, R. Lee, J. Auten, A. Wolf, B. Du, L. Rabin, B. H. Hahn, E. Terwilliger, and J. M. McCune, Virology 227:46–52, 1997). Here we further demonstrate that HIV-1 replication in vivo can be separated from its pathogenic activity, in that the HXB/LW virus replicated to high levels in SCID-hu Thy/Liv mice, with no significant thymocyte depletion. Restoration of the nef gene in the recombinant HXB/LW genome restored its pathogenic activity, with no significant effect on HIV-1 replication in the thymus. Our results suggest that in vitro-attenuated HIV-1 lacks determinants for pathogenicity as well as for replication in vivo. Our data indicate that (i) the replication defect can be recovered in vivo by mutations in the envgene, without an associated pathogenic phenotype, and (ii)nef can function in the HXB/LW clone as a pathogenic factor that does not enhance HIV-1 replication in the thymus. Furthermore, the HXB/LW virus may be used to study mechanisms of HIV-1nef-mediated pathogenesis in vivo.

To the bibliography