Relevant bibliographies by topics / Gynura procumbens

Academic literature on the topic 'Gynura procumbens'

Author: Grafiati
Published: 10 December 2022
Last updated: 29 January 2023

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Journal articles on the topic "Gynura procumbens"

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Selviani, Amalia, Sugito Sugito, and Sutriswanto Sutriswanto. "Pengaruh Variasi Konsentrasi Ekstrak Daun Sambung Nyawa terhadap Zona Hambat Bakteri Escherichia Coli Metode Difusi." Jurnal Laboratorium Khatulistiwa 2, no. 2 (July 7, 2019): 44. http://dx.doi.org/10.30602/jlk.v2i2.328.

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Abstract: Gynura procumbens plants or often called Gynura procumbens (Lour.) Merr is a plant belonging to the Asteraceae family. Based on the results of phytochemical screening performed, the chemical content contained in the leaves of Gynura procumbens (Lour).Merr is phenol, saponin and steroid. Phenol and saponin each have a mechanism as an antibacterial. The purpose of this study was to determine the inhibition zone of Gynura procumbens extract, concentration of 10%, 20%, 30%, 40% dan 50% to Escherichia coli bacteria on hook moutellic agar and to know the value of Resistant, Intermediate and Sensitive from leaf extract of Gynura procumbens (Lour).Merr against bacterial inhibition zone of Escherichia coli, as well as to analyze the effect of concentration variation of Gynura procumbens (Lour).Merr leaf extract to the inhibitory zone of Escherichia coli bacteria. The research method used is experimental method. Based on the result of the research, it is known that Gynura procumbens (Lour).Merr leaf extract have inhibition zone to Escherichia coli bacteria with the width of the lowest barrier zone of 6 mm at 10% concentration while the width of the highest resistance zone is 20 mm at concentration 50% with 30 mm control. From the statistical test result using Simple Linear Regression, the result of p(0,000) at 95% confdence level (p = 0,000 <α (0,05) meaning that there is influence of concentration of Gynura procumbens (Lour).Merr leaf extract to zone inhibit of Escherichia coli bacteria diffusion method.Abstrak: Tanaman sambung nyawa atau sering disebut dengan Gynura procumbens (Lour.) Merr merupakan tanaman yang termasuk dalam famili Asteraceae. Berdasarkan hasil skrining ftokimia yang dilakukan, kandungan kimia yang terdapat di dalam daun sambung nyawa adalah fenol, saponin dan steroid. Senyawa fenol dan saponin memiliki mekanisme sebagai antibakteri. Penelitian ini bertujuan untuk mengetahui zona hambat dari ekstrak daun sambung nyawa konsentrasi 10%, 20%, 30%,40% dan 50% terhadap bakteri Escherichia coli pada media muller hinton agar dan untuk mengetahui nilai Resisten, Intermediet dan Sensitif dari ekstrak daun sambung nyawa (Gynura procumbens (Lour).Merr) terhadap zona hambat bakteri Escherichia coli serta menganalisis pengaruh variasi konsentrasi ekstrak daun sambung nyawa (Gynura procumbens (Lour).Merr) terhadap zona hambat bakteri Escherichia coli. Metode penelitian yang digunakan adalah metode ekperimental semu. Berdasarkan hasil penelitian diketahui bahwa ekstrak daun sambung nyawa mempunyai zona hambat terhadap bakteri Escherichia coli dengan luas zona hambatan terendah 6 mm pada konsentrasi 10% sedangkan luas zona hambatan tertinggi 20 mm pada konsentrasi 50% dengan kontrol pembanding sebesar 30 mm. Dari hasil uji statistik menggunakan Regresi Linier Sederhana, didapatkan hasil p (0,000) pada tingkat kepercayaan 95% (p=0,000 < α (0,05) yang berarti ada pengaruh variasi konsentrasi ekstrak daun sambung nyawa terhadap zona hambat bakteri Escherichia coli metode difusi.
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Haque, Ehfazul, Mir Shahriar Kamal, Md Rafat Tahsin, Raju Ahmed, Jakir Ahmed Choudhury, Abu Asad Chowdhury, Shaila Kabir, Md Shah Amran, and Md Sahab Uddin. "Current Knowledge Regarding Pharmacological Profile and Chemical Constituents of Gynura procumbens." Current Topics in Medicinal Chemistry 21, no. 29 (December 22, 2021): 2671–86. http://dx.doi.org/10.2174/1568026621666211004094902.

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Gynura procumbens (Lour.) Merr. is a well-known plant used in folkloric medicine in tropical Asian countries. The plant is prevalently employed by traditional healers in the treatment of diabetes, cancer, hypertension, inflammation, fever, and skin disorders. Several scientific studies reported that Gynura procumbens possesses considerable therapeutic value for the development of emerging treatment options. The diverse pharmacological effects of this plant are attributed to its vast phytoconstituent content. Different chemical classes, including alkaloids, flavonoids, phenolics, steroids, proteins, and polysaccharides, have been isolated from this plant. In this review, we tried to explore the different aspects of Gynura procumbens as an established medicinal plant. The data gathered here give an indication that the plant Gynura procumbens is a good natural source of chemical compounds with different types of pharmacological actions, and these chemical compounds can be used as models for the development of de novo therapeutic agents.
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Haque, Ehfazul, Mir Shahriar Kamal, Md Rafat Tahsin, Raju Ahmed, Jakir Ahmed Choudhury, Abu Asad Chowdhury, Shaila Kabir, Md Shah Amran, and Md Sahab Uddin. "Current Knowledge Regarding Pharmacological Profile and Chemical Constituents of Gynura procumbens." Current Topics in Medicinal Chemistry 21, no. 29 (December 22, 2021): 2671–86. http://dx.doi.org/10.2174/1568026621666211004094902.

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Gynura procumbens (Lour.) Merr. is a well-known plant used in folkloric medicine in tropical Asian countries. The plant is prevalently employed by traditional healers in the treatment of diabetes, cancer, hypertension, inflammation, fever, and skin disorders. Several scientific studies reported that Gynura procumbens possesses considerable therapeutic value for the development of emerging treatment options. The diverse pharmacological effects of this plant are attributed to its vast phytoconstituent content. Different chemical classes, including alkaloids, flavonoids, phenolics, steroids, proteins, and polysaccharides, have been isolated from this plant. In this review, we tried to explore the different aspects of Gynura procumbens as an established medicinal plant. The data gathered here give an indication that the plant Gynura procumbens is a good natural source of chemical compounds with different types of pharmacological actions, and these chemical compounds can be used as models for the development of de novo therapeutic agents.
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Meiyanto, Edy. "EKSTRAK ETANOLIK DAUN Gynura procumbens (Luor) Merr. MENGHAMBAT PROLIFERASI SEL KANKER PAYUDARA TIKUS PADA KARSINOGENESIS YANG DIINDUKSI DENGAN dimetilbenz(a)antrazena (DMBA)." Pharmacon: Jurnal Farmasi Indonesia 13, no. 1 (January 27, 2015): 12–17. http://dx.doi.org/10.23917/pharmacon.v13i1.21.

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Penelitian sebelumnya menunjukkan bahwa ekstrak etanolik daun Gynura procumbens dapat menghambat pertumbuhan tumor payudara tikus yang diinduksi DMBA. Penelitian ini bertujuan untuk mengetahui efek ekstrak etanolik daun Sambung nyawa (Gynura procumbens (Luor) Merr) pada proliferasi sel kanker payudara tikus yang diinduksi dengan Dimetilbenz(a)antrazena (DMBA). Enam puluh ekor tikus betina galur SD umur 6 minggu dibagi menjadi 6 kelompok yaitu tanpa perlakuan, perlakuan DMBA saja dan empat kelompok perlakuan DMBA+ekstrak. Inisiasi DMBA dilakukan dengan dosis 20 mg/kgBB yang diberikan sebanyak 10 kali dengan frekuensi pemberian 2 kali setiap minggu. Mulai minggu ke-1 (post I) atau ke-6 (post II) kelompok perlakuan mendapat ekstrak etanolik daun Gynura procumbens dalam CMC 0,5 % seminggu 3 kali melalui oral dengan dosis 250 mg/kgBB dan 750 mg/kgBB. Pada minggu ke-16 tikus dikorbankan, jaringan payudara diambil untuk dibuat preparat histologi dengan teknik pewarnaan silver (AgNOR). Mean AgNOR (mAgNOR) dihitung pada setiap preparat tiap kelompok. mAgNOR kelompok perlakuan dibandingkan dengan mAgNOR kelompok tanpa perlakuan. Hasil penelitian menunjukkan ekstrak etanolik daun Gynura procumbens dengan dosis 250 mg/kgBB dan 750 mg/kgBB yang diberikan mulai minggu kesatu maupun ke-6 setelah inisiasi DMBA terakhir dapat mengurangi proliferasi sel kanker payudara tikus. Rata-rata mAgNOR kelompok tanpa perlakuan dan perlakuan DMBA saja masing-masing 0,8 ± 0,34 dan 2,7 ± 0,41, mAgNOR post I kelompok dosis 250 dan dosis 750 masing-masing 1,4 ± 0,39 dan 1,3 ± 0,09, sedangkan mAgNOR post II kelompok dosis 250 dan dosis 750 masing-masing 1,6 ± 0,47 dan 1,5 ± 0,31. Pengamatan terhadap ekspresi COX-2 menunjukkan adanya penurunan pada kelompok perlakuan ekstrak dosis 250 dan 750 mg/kgBB. Hasil-hasil tersebut menunjukkan bahwa ekstrak etanolik daun Gynura procumbens dapat menghambat proliferasi sel-sel tumor payudara yang kemungkinan berhubungan dengan penurunan ekspresi COX-2. Kata kunci: Gynura procumbens, anti-karsinogenesis, proliferasi, AgNOR
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Uthia, Rahimatul, Dina Yuliana, and Widya Kardela. "Antihypertension Activity of Gynura procumbens (L.) Merr. Extract On Blood Pressure And Monoxide Nitrogen Levels In Male White Rats." JPK : Jurnal Proteksi Kesehatan 9, no. 2 (July 6, 2021): 25–31. http://dx.doi.org/10.36929/jpk.v9i2.309.

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Hypertension is closely related to vasodilation disorders because of the decreased availability of nitrogen monoxide (NO). The purpose of this study was to determine the decrease in blood pressure and nitrogen monoxide (NO) levels in rats after administration of Gynura procumbens leaves extract. The results showed that the administration of Gynura procumbens leaves extracts significantly reduced blood pressure and increased NO levels. From the results of Duncan's test, it was found that the dose of 300mg / Kg BW showed a better effect on increasing NO levels (p <0.05). From the results of the study, it can be concluded that the ethanol extract of Gynura procumbens leaves has an antihypertensive activity that can reduce blood pressure and increase the NO level.
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Rosidah, Mun Yam, Amirin Sadikun, and Mohd Asmawi. "Antioxidant Potential of Gynura procumbens." Pharmaceutical Biology 46, no. 9 (January 2008): 616–25. http://dx.doi.org/10.1080/13880200802179642.

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Hamid, Iwan Sahrial, Yuseni Kusuma P., Retno Bijanti, and Bimo Aksono. "The Number of Macrophages and Heterophils on Chick Embryo Chorioallantoic Membrane After Gynura procumbens (Lour) Merr Extract Treatment and bFgF Induction." Indonesian Journal of Cancer Chemoprevention 3, no. 2 (June 30, 2012): 398. http://dx.doi.org/10.14499/indonesianjcanchemoprev3iss2pp398-403.

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Antiangiogenesis (inhibition of new blood vessels formation) has become a strategy to inhibit cancer development. The aim of this experiment was to investigate antiangiogenic effect of Gynura procumbens (Lour) Merr focusing on the decreasing of the number of macrophages and heterophils on chick embryo chorioallantoic membrane. Nine-days-aged-eggs were divided into six groups (eight eggs each group). Group I (positive control) eggs were induced with bFGF+Tris HCl. Group II (negative control) eggs were treated with DMSO+Tris HCl. Group III (treatment I) eggs were induced with 60 ng bFGF and treated with ethanolic extract of G. procumbens leaves with the dose of 60 µg. The following treatment groups, i.e. group IV (treatment II), group V (treatment III), and group VI (treatment IV) were treated with increasing dose of extract, starting from 75 µg, 90 µg, and the last was 110 µg. Eggs were incubated until they reach the age of twelve days to observe macrophages, while to observe heterophils, eggs were incubated until the age of seventeen days. Based on haematoxylin-eosin staining, macrophages in the treatment groups were less than the control positive group (bFGF+Tris HCl), but based on giemsa staining, the effect of Gynura procumbens in decreasing the number of heterophils could not be observed because some blood smears. These analysis suggest that the ethanolic extract of Gynura procumbens leaves can perform as antiangiogenic agent decreasing the number of macrophages.Keywords: antiangiogenic, macrophages, heterophils, Gynura procumbens
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Ishak, Pertiwi, Peter Kabo, and Yulia Yusrini Djabir. "Nefroprotective Effect of Gynura procumbens Extract Against Paracetamol Toxicity in Rats." Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) 7, no. 2 (October 4, 2021): 181–90. http://dx.doi.org/10.22487/j24428744.2021.v7.i2.15584.

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ABSTRACT Excessive doses of paracetamol have the potential to cause acute kidney injury and even death. Gynura procumbens has been traditionally used as folk-medicine for kidney disease. This study aimed to examine the nephroprotective effect of Gynura procumbens leaf extract against paracetamol-induced nephrotoxicity in rats. Twenty-five male wistar rats (150-200 g) were divided into 5 groups. Healthy control group, placebo group, and 3 extract treatment groups that received either 100 mg/kg, 200 mg/kg or 300 mg/kg dose. The placebo (sodium carboxymethyl cellulose) or extract was given 4 consecutive days prior to paracetamol (2400 mg/kg) administration on day 5. Blood samples were withdrawn before treatment initiated (day 0), after treatment before paracetamol administration (day 5) and 24-hour after paracetamol administration (day 6). Blood samples were analyzed to obtain urea and creatinine levels. In addition, histopathological analysis was performed on the renal tissue. Paracetamol administration was shown to significantly increase the urea and creatinine levels, and the extract at 300 mg/kg dose was able to significantly prevent the elevation of the renal biomarkers. The histopathological analysis also revealed a significant reduction in renal histopathological injury in 300 mg/kg extract group. It can be concluded that the ethanolic extract of the Gynura procumbens at a dose of 300 mg/kg has a good protective effect on kidney function and tissue structure. Key words: Gynura procumbens, nephroprotective, paracetamol
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Ishak, Pertiwi, Peter Kabo, and Yulia Yusrini Djabir. "Nefroprotective Effect of Gynura procumbens Extract Against Paracetamol Toxicity in Rats." Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) (e-Journal) 7, no. 2 (October 4, 2021): 181–90. http://dx.doi.org/10.22487/j24428744.2021.v7.i2.15584.

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ABSTRACT Excessive doses of paracetamol have the potential to cause acute kidney injury and even death. Gynura procumbens has been traditionally used as folk-medicine for kidney disease. This study aimed to examine the nephroprotective effect of Gynura procumbens leaf extract against paracetamol-induced nephrotoxicity in rats. Twenty-five male wistar rats (150-200 g) were divided into 5 groups. Healthy control group, placebo group, and 3 extract treatment groups that received either 100 mg/kg, 200 mg/kg or 300 mg/kg dose. The placebo (sodium carboxymethyl cellulose) or extract was given 4 consecutive days prior to paracetamol (2400 mg/kg) administration on day 5. Blood samples were withdrawn before treatment initiated (day 0), after treatment before paracetamol administration (day 5) and 24-hour after paracetamol administration (day 6). Blood samples were analyzed to obtain urea and creatinine levels. In addition, histopathological analysis was performed on the renal tissue. Paracetamol administration was shown to significantly increase the urea and creatinine levels, and the extract at 300 mg/kg dose was able to significantly prevent the elevation of the renal biomarkers. The histopathological analysis also revealed a significant reduction in renal histopathological injury in 300 mg/kg extract group. It can be concluded that the ethanolic extract of the Gynura procumbens at a dose of 300 mg/kg has a good protective effect on kidney function and tissue structure. Key words: Gynura procumbens, nephroprotective, paracetamol
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Kim, Kyeong Jin, Ah Hyun Gim, Ji Hyun Kim, Do Hee Kim, Seo Rin Lee, Jee Hyun Park, Ji Won Lim, Ji Hoon Ha, and Soo Nam Park. "Antioxidant Activities of Gynura procumbens Extracts." Journal of the Society of Cosmetic Scientists of Korea 41, no. 2 (June 30, 2015): 181–87. http://dx.doi.org/10.15230/scsk.2015.41.2.181.

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Book chapters on the topic "Gynura procumbens"

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Sastry, K. Subramanya, Bikash Mandal, John Hammond, S. W. Scott, and R. W. Briddon. "Gynura procumbens (Longevity spinach)." In Encyclopedia of Plant Viruses and Viroids, 1124. New Delhi: Springer India, 2019. http://dx.doi.org/10.1007/978-81-322-3912-3_432.

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Conference papers on the topic "Gynura procumbens"

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Nadzir, Masrina Mohd, Farhana Nazira Idris, and Khairunisa Hat. "Green synthesis of silver nanoparticle using Gynura procumbens aqueous extracts." In 6TH INTERNATIONAL CONFERENCE ON ENVIRONMENT (ICENV2018): Empowering Environment and Sustainable Engineering Nexus Through Green Technology. AIP Publishing, 2019. http://dx.doi.org/10.1063/1.5117140.

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Khaidatul Akmar, K., and M. N. Mahanem. "Profertility and antidiabetic properties of Gynura procumbens on streptozotocin induced male rats." In THE 2016 UKM FST POSTGRADUATE COLLOQUIUM: Proceedings of the Universiti Kebangsaan Malaysia, Faculty of Science and Technology 2016 Postgraduate Colloquium. Author(s), 2016. http://dx.doi.org/10.1063/1.4966737.

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Sugiharto, Ummi Zubaidah, Dwi Winarni, and Yosephine Sri Wulan Manuhara. "Gynura procumbens methanolic extracts suppresses proliferation of hepatocellular carcinoma: In vitro assay." In THE 8TH INTERNATIONAL CONFERENCE AND WORKSHOP ON BASIC AND APPLIED SCIENCE (ICOWOBAS) 2021. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0104809.

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Lee Hyeon, W., H. Ryu Ga, S. Yang Woo, and J. Ma Choong. "Gynura Procumbens (Lour.) Merr Inhibits the Glutamate Induced Toxicity in Neuronal Cell Lines." In GA 2017 – Book of Abstracts. Georg Thieme Verlag KG, 2017. http://dx.doi.org/10.1055/s-0037-1608448.

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Kusuma, Dannis Y., Alfinda N. Kristanti, and Yosephine S. W. Manuhara. "Continuous subcultures effect on Gynura procumbens Lour. (Merr.) branch number and root length." In THE 8TH INTERNATIONAL CONFERENCE AND WORKSHOP ON BASIC AND APPLIED SCIENCE (ICOWOBAS) 2021. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0104750.

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Triwijayanti, Ely, Anggela Hajar Puspitasari, Triyono Adi Purnomo, Nindi Novia Erin, Syifa Fajrisani, Arif Yachya, and Yosephine Sri Wulan Manuhara. "Total phenolic, flavonoid, and saponin content of methanol extract from the medical plant Gynura procumbens." In THE 8TH INTERNATIONAL CONFERENCE AND WORKSHOP ON BASIC AND APPLIED SCIENCE (ICOWOBAS) 2021. AIP Publishing, 2023. http://dx.doi.org/10.1063/5.0106275.

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Tristantini, Dewi, Nathanael Sandy, Ricky Kristanda Suwignjo, and Leon Lukhas Santoso. "Antioxidant properties assay of Gynura procumbens L. fresh juice in various shelf-life time using hydroxyl radical scavenging method." In THE 5TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, AND MEDICAL DEVICES: Proceedings of the 5th International Symposium of Biomedical Engineering (ISBE) 2020. AIP Publishing, 2021. http://dx.doi.org/10.1063/5.0049273.

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Nurisa, Aryana, Alfinda Novi Kristanti, and Yosephine Sri Wulan Manuhara. "Effect of sucrose, erythrose-4-phosphate and phenylalanine on biomassa and flavonoid content of callus culture from leaves of Gynura procumbens Merr." In THE 4TH INTERNATIONAL CONFERENCE ON RESEARCH, IMPLEMENTATION, AND EDUCATION OF MATHEMATICS AND SCIENCE (4TH ICRIEMS): Research and Education for Developing Scientific Attitude in Sciences And Mathematics. Author(s), 2017. http://dx.doi.org/10.1063/1.4995205.

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