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Journal articles on the topic 'Guided Tissue Regeneration'

Author: Grafiati

Published: 4 June 2021

Last updated: 31 July 2024

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1

Batwa, Mohammed, Rand Bakhsh, Zainab Alghamdi, Khaled Ageely, Abdullah Alzahrani, Abdullah Alshahrani, Khalid Mujthil, et al. "Regenerative Therapies in the Treatment of Periodontal Defects." JOURNAL OF HEALTHCARE SCIENCES 03, no. 08 (2023): 254–60. http://dx.doi.org/10.52533/johs.2023.30802.

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Regenerative therapies in periodontics have shown great potential in restoring damaged periodontal tissues. Techniques such as guided tissue regeneration (GTR) and guided bone regeneration (GBR) have been effective in promoting the regeneration of periodontal ligament, cementum, and alveolar bone. These approaches create a conducive environment for cell repopulation and exclusion of non-osteogenic cells, leading to successful periodontal tissue regeneration. Tissue engineering approaches, utilizing stem cells, growth factors, and biomaterial scaffolds, have also shown promise in regenerating multiple periodontal tissues simultaneously. However, challenges such as membrane exposure and infection need to be addressed. Emerging regenerative techniques, including enamel matrix derivatives (EMDs), stem cell-based therapies, growth factor delivery systems, and gene therapies, offer innovative strategies for periodontal defect treatment. Optimization of delivery systems, refinement of biomaterials, and advancements in gene therapy and tissue-specific biomaterials may further enhance the regenerative capacity of periodontal tissues. Despite challenges, regenerative therapies have the potential to revolutionize periodontics and improve clinical outcomes by addressing the root cause of periodontal diseases and promoting long-lasting tissue regeneration.

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2

Cahaya, Cindy, and Sri Lelyati C. Masulili. "Perkembangan Terkini Membran Guided Tissue Regeneration/Guided Bone Regeneration sebagai Terapi Regenerasi Jaringan Periodontal." Majalah Kedokteran Gigi Indonesia 1, no. 1 (June 1, 2015): 1. http://dx.doi.org/10.22146/majkedgiind.8810.

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Periodontitis adalah salah satu penyakit patologis yang mempengaruhi integritas sistem periodontal yang menyebabkan kerusakan jaringan periodontal yang berlanjut pada kehilangan gigi. Beberapa tahun belakangan ini banyak ketertarikan untuk melakukan usaha regenerasi jaringan periodontal, tidak saja untuk menghentikan proses perjalanan penyakit namun juga mengembalikan jaringan periodontal yang telah hilang. Sasaran dari terapi regeneratif periodontal adalah menggantikan tulang, sementum dan ligamentum periodontal pada permukaan gigi yang terkena penyakit. Prosedur regenerasi antara lain berupa soft tissue graft, bone graft, biomodifikasi akar gigi, guided tissue regeneration sertakombinasi prosedur-prosedur di atas, termasuk prosedur bedah restoratif yang berhubungan dengan rehabilitasi oral dengan penempatan dental implan. Pada tingkat selular, regenerasi periodontal adalah proses kompleks yang membutuhkan proliferasi yang terorganisasi, differensiasi dan pengembangan berbagai tipe sel untuk membentuk perlekatan periodontal. Rasionalisasi penggunaan guided tissue regeneration sebagai membran pembatas adalah menahan epitel dan gingiva jaringan pendukung, sebagai barrier membrane mempertahankan ruang dan gigi serta menstabilkan bekuan darah. Pada makalah ini akan dibahas sekilas mengenai 1. Proses penyembuhan terapi periodontal meliputi regenerasi, repair ataupun pembentukan perlekatan baru. 2. Periodontal spesific tissue engineering. 3. Berbagai jenis membran/guided tissue regeneration yang beredar di pasaran dengan keuntungan dan kerugian sekaligus karakteristik masing-masing membran. 4. Perkembangan membran terbaru sebagai terapi regenerasi penyakit periodontal. Tujuan penulisan untuk memberi gambaran masa depan mengenai terapi regenerasi yang menjanjikan sebagai perkembangan terapi penyakit periodontal. Latest Development of Guided Tissue Regeneration and Guided Bone Regeneration Membrane as Regenerative Therapy on Periodontal Tissue. Periodontitis is a patological state which influences the integrity of periodontal system that could lead to the destruction of the periodontal tissue and end up with tooth loss. Currently, there are so many researches and efforts to regenerate periodontal tissue, not only to stop the process of the disease but also to reconstruct the periodontal tissue. Periodontal regenerative therapy aims at directing the growth of new bone, cementum and periodontal ligament on the affected teeth. Regenerative procedures consist of soft tissue graft, bone graft, roots biomodification, guided tissue regeneration and combination of the procedures, including restorative surgical procedure that is connected with oral rehabilitation with implant placement. At cellular phase, periodontal regeneration is a complex process with well-organized proliferation, distinction, and development of various type of cell to form attachment of periodontal tissue. Rationalization of the use of guided tissue regeneration as barrier membrane is to prohibit the penetration of epithelial and connective tissue migration into the defect, to maintain space, and to stabilize the clot. This research discusses: 1. Healing process on periodontal therapy including regeneration, repair or formation of new attachment. 2. Periodontal specific tissue engineering. 3. Various commercially available membrane/guided tissue regeneration in the market with its advantages and disadvantages and their characteristics. 4. Recent advancement of membrane as regenerative therapy on periodontal disease. In addition, this review is presented to give an outlook for promising regenerative therapy as a part of developing knowledge and skills to treat periodontal disease.

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3

Villar, Cristina C., and David L. Cochran. "Regeneration of Periodontal Tissues: Guided Tissue Regeneration." Dental Clinics of North America 54, no. 1 (January 2010): 73–92. http://dx.doi.org/10.1016/j.cden.2009.08.011.

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4

Wagle, ShreeprasadVijay, AmitArvind Agrawal, Dinaz Bardoliwala, and Chhaya Patil. "Guided tissue regeneration." Journal of Oral Research and Review 13, no. 1 (2021): 46. http://dx.doi.org/10.4103/jorr.jorr_11_20.

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5

Dowell, P., J. Moran, and D. Quteish. "Guided tissue regeneration." British Dental Journal 171, no. 5 (September 1991): 125–27. http://dx.doi.org/10.1038/sj.bdj.4807634.

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6

Gilbert Triplett, R. "Guided Tissue Regeneration." Atlas of the Oral and Maxillofacial Surgery Clinics 2, no. 2 (September 1994): 93–108. http://dx.doi.org/10.1016/s1061-3315(18)30135-5.

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7

Karring, Thorkild. "Guided Tissue Regeneration." Advances in Dental Research 9, no. 3_suppl (November 1995): 18. http://dx.doi.org/10.1177/0895937495009003s0901.

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8

Gómez, Felipe. "Update on Histological Evidence of Tissue Formed by Guided Pulp Tissue Regeneration." International Journal of Medical and Surgical Sciences 3, no. 2 (October 26, 2018): 881–88. http://dx.doi.org/10.32457/ijmss.2016.021.

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The goal of regenerative endodontics is to reinstate normal pulp function in traumatized, necrotic and infected teeth that would result in reestablishment of their functions, but still fail to re-establish real pulp tissue and give unpredictable results. The aim of this review was to compile and synthesize available information on the histological evidence of tissue pulp-dentinal complex formed through guided tissue regeneration. A web-based research on MEDLINE was done using filter terms Review, published in the last 10 years and Dental journals. Keywords used for research were “Pulp", "Dentin", "Regeneratión", "Tissue” and "Histologic". The search yielded about 140 articles; the interest were selected and downloaded in full text. The most encouraging studies regarding guided tissue regeneration have been described in case reports of immature teeth diagnosed with irreversible pulpitis in which the histology odontoblasts type cells were observed. However, there are no studies with long-term follow up on this type of therapy. Some treatment protocols might result in undesired and unpredictable outcomes. Efforts are required to improve and update existing regenerative endodontic strategies to make it an effective, safe, and biological mode to save teeth.

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9

Saravanakumar, R., M. Jananni, V. Arvind Raaj, and KR Vineela. "Guided Tissue Regeneration Membrane." Annals of SBV 3, no. 2 (2014): 7–13. http://dx.doi.org/10.5005/jp-journals-10085-3202.

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10

Laurell, Lars, and Jan Gottlow. "Guided tissue regeneration update." International Dental Journal 48, no. 4 (August 1998): 386–98. http://dx.doi.org/10.1111/j.1875-595x.1998.tb00701.x.

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11

Lewandowska, Katarzyna, and Gabriel Furtos. "CHARACTERISATION OF THIN CHITOSAN FILMS FOR GUIDED TISSUE REGENERATION PURPOSES." Progress on Chemistry and Application of Chitin and its Derivatives XXII (September 30, 2017): 118–24. http://dx.doi.org/10.15259/pcacd.22.11.

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12

van den Beucken, Jeroen J. J. P., Lise T. de Jonge, Adelina S. Plachokova, and John A. Jansen. "Enzymatically Enhanced Guided Tissue Regeneration." Bioceramics Development and Applications 1 (2011): 1–3. http://dx.doi.org/10.4303/bda/d110158.

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13

Richie-Gillespie, Ray. "Guided tissue regeneration in endodontics." Journal of Endodontics 22, no. 8 (August 1996): 443. http://dx.doi.org/10.1016/s0099-2399(96)80254-8.

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14

Baikm, B. E. "Guided Tissue and Bone Regeneration." Implant Dentistry 6, no. 1 (1997): 47. http://dx.doi.org/10.1097/00008505-199700610-00020.

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15

Vedhanayagam, Mohan, Iruthayapandi Selestin Raja, Anara Molkenova, Timur Sh Atabaev, Kalarical Janardhanan Sreeram, and Dong-Wook Han. "Carbon Dots-Mediated Fluorescent Scaffolds: Recent Trends in Image-Guided Tissue Engineering Applications." International Journal of Molecular Sciences 22, no. 10 (May 20, 2021): 5378. http://dx.doi.org/10.3390/ijms22105378.

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Regeneration of damaged tissues or organs is one of the significant challenges in tissue engineering and regenerative medicine. Many researchers have fabricated various scaffolds to accelerate the tissue regeneration process. However, most of the scaffolds are limited in clinical trials due to scaffold inconsistency, non-biodegradability, and lack of non-invasive techniques to monitor tissue regeneration after implantation. Recently, carbon dots (CDs) mediated fluorescent scaffolds are widely explored for the application of image-guided tissue engineering due to their controlled architecture, light-emitting ability, higher chemical and photostability, excellent biocompatibility, and biodegradability. In this review, we provide an overview of the recent advancement of CDs in terms of their different synthesis methods, tunable physicochemical, mechanical, and optical properties, and their application in tissue engineering. Finally, this review concludes the further research directions that can be explored to apply CDs in tissue engineering.

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16

González-Jaranay, Maximino, María del Carmen Sánchez-Quevedo, Gerardo Moreu, José Manuel García, and Antonio Campos. "Electron Microprobe Analysis in Guided Tissue Regeneration: A Case Report." European Journal of Dentistry 01, no. 01 (January 2007): 40–44. http://dx.doi.org/10.1055/s-0039-1698310.

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ABSTRACTObjectives: Several procedures have been advocated as regenerative procedures in periodontology, but one of the most widely used techniques up to now is guided tissue regeneration (GTR). Likewise, different assessment methods based on clinical, radiographic or histological measurements have been proposed for the evaluation of these regenerative procedures. However, none of the methods used for human material incorporates quantitative X-ray microanalysis to assess the degree of mineralization of the regenerated periodontal hard tissues. The objective of this report was to evaluate, using quantitative X-ray microprobe analysis, the newly-formed hard tissue in a periodontal infrabony defect.Methods: Electron microprobe analysis was used to study the nature of the newly-formed hard tissue 3 years after treatment with guided tissue regeneration in a patient with localized aggressive periodontitis.Results: Our quantitative analyses, using the peak-to-background method, showed calcium/phosphorus mass ratio of 1.50±0.38 in the newly-formed hard tissue around the affected tooth root.Conclusion: Quantitative X-ray microprobe analysis is a useful tool that may provide an accurate assessment of the degree of mineralization in an extremely small tissue sample. (Eur J Dent 2007;1:40- 44)

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17

Thomas, Nebu George, Betcy Thomas, Thomas George Velliavettil, TV Anilkumar, and Pratheesh KV. "An application of decellularized membrane as guided tissue regeneration." IP International Journal of Periodontology and Implantology 8, no. 3 (September 15, 2023): 129–35. http://dx.doi.org/10.18231/j.ijpi.2023.026.

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Decellularized Extracellular Matrix (DECM) has been established as a biomaterial that retains the natural properties of a tissue, promotes cell proliferation and cell differentiation. Periodontal regeneration requires the neovascularization niches and the proliferation and differentiation of the involved cells. DECM have various advantages and qualities in terms of stimulating periodontal tissue regeneration. Several methods for improving mechanical strength of the scaffolds have been identified like, crosslinking which is to enhance regenerative potential. This review focuses on the ability of DECM to repair damaged tissue in periodontal tissue engineering and addresses the future direction of periodontal regeneration in particular area.

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18

Ashfaq, Rabia, Anita Kovács, Szilvia Berkó, and Mária Budai-Szűcs. "Developments in Alloplastic Bone Grafts and Barrier Membrane Biomaterials for Periodontal Guided Tissue and Bone Regeneration Therapy." International Journal of Molecular Sciences 25, no. 14 (July 15, 2024): 7746. http://dx.doi.org/10.3390/ijms25147746.

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Periodontitis is a serious form of oral gum inflammation with recession of gingival soft tissue, destruction of the periodontal ligament, and absorption of alveolar bone. Management of periodontal tissue and bone destruction, along with the restoration of functionality and structural integrity, is not possible with conventional clinical therapy alone. Guided bone and tissue regeneration therapy employs an occlusive biodegradable barrier membrane and graft biomaterials to guide the formation of alveolar bone and tissues for periodontal restoration and regeneration. Amongst several grafting approaches, alloplastic grafts/biomaterials, either derived from natural sources, synthesization, or a combination of both, offer a wide variety of resources tailored to multiple needs. Examining several pertinent scientific databases (Web of Science, Scopus, PubMed, MEDLINE, and Cochrane Library) provided the foundation to cover the literature on synthetic graft materials and membranes, devoted to achieving periodontal tissue and bone regeneration. This discussion proceeds by highlighting potential grafting and barrier biomaterials, their characteristics, efficiency, regenerative ability, therapy outcomes, and advancements in periodontal guided regeneration therapy. Marketed and standardized quality products made of grafts and membrane biomaterials have been documented in this work. Conclusively, this paper illustrates the challenges, risk factors, and combination of biomaterials and drug delivery systems with which to reconstruct the hierarchical periodontium.

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19

Alqahtani, Ali M. "Guided Tissue and Bone Regeneration Membranes: A Review of Biomaterials and Techniques for Periodontal Treatments." Polymers 15, no. 16 (August 10, 2023): 3355. http://dx.doi.org/10.3390/polym15163355.

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This comprehensive review provides an in-depth analysis of the use of biomaterials in the processes of guided tissue and bone regeneration, and their indispensable role in dental therapeutic interventions. These interventions serve the critical function of restoring both structural integrity and functionality to the dentition that has been lost or damaged. The basis for this review is laid through the exploration of various relevant scientific databases such as Scopus, PubMed, Web of science and MEDLINE. From a meticulous selection, relevant literature was chosen. This review commences by examining the different types of membranes used in guided bone regeneration procedures and the spectrum of biomaterials employed in these operations. It then explores the manufacturing technologies for the scaffold, delving into their significant impact on tissue and bone regenerations. At the core of this review is the method of guided bone regeneration, which is a crucial technique for counteracting bone loss induced by tooth extraction or periodontal disease. The discussion advances by underscoring the latest innovations and strategies in the field of tissue regeneration. One key observation is the critical role that membranes play in guided reconstruction; they serve as a barrier, preventing the entry of non-ossifying cells, thereby promoting the successful growth and regeneration of bone and tissue. By reviewing the existing literature on biomaterials, membranes, and scaffold manufacturing technologies, this paper illustrates the vast potential for innovation and growth within the field of dental therapeutic interventions, particularly in guided tissue and bone regeneration.

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20

Isobe, Shuichi. "Ultrastructural Study of Regenerative Connective Tissue Attachment by Guided Tissue Regeneration(GTR)." Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) 39, no. 2 (1997): 167–83. http://dx.doi.org/10.2329/perio.39.167.

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21

Boyne, Philip J. "The Evolution of Guided Tissue Regeneration." Oral and Maxillofacial Surgery Clinics of North America 13, no. 3 (August 2001): 397–409. http://dx.doi.org/10.1016/s1042-3699(20)30126-6.

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22

Dyer, Bret L., Raul G. Caffesse, Carlos E. Nasjleti, and Edith C. Morrison. "Guided Tissue Regeneration With Dentin Biomodification." Journal of Periodontology 64, no. 11 (November 1993): 1052–60. http://dx.doi.org/10.1902/jop.1993.64.11.1052.

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23

Tinti, Carlo, Giampaolo Vincenzi, and Roberto Cocchetto. "Guided Tissue Regeneration in Mucogingival Surgery." Journal of Periodontology 64, no. 11s (November 1993): 1184–91. http://dx.doi.org/10.1902/jop.1993.64.11s.1184.

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24

GREENSTEIN, GARY, and JACK G. CATON. "Biodegradable barriers and guided tissue regeneration." Periodontology 2000 1, no. 1 (February 1993): 36–45. http://dx.doi.org/10.1111/j.1600-0757.1993.tb00205.x.

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25

Nyman, Sture R., and Niklaus P. Lang. "Guided tissue regeneration and dental implants." Periodontology 2000 4, no. 1 (February 1994): 109–18. http://dx.doi.org/10.1111/j.1600-0757.1994.tb00011.x.

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26

PRATO, GIOVANPAOLO PINI, CARLO CLAUSER, MAURIZIO S. TONETTI, and PIERPAOLO CORTELLINI. "Guided tissue regeneration in gingival recessions." Periodontology 2000 11, no. 1 (June 1996): 49–57. http://dx.doi.org/10.1111/j.1600-0757.1996.tb00182.x.

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27

Ferris, Robert T. "A review of guided tissue regeneration." International Dental Journal 48 (June 1998): 322–25. http://dx.doi.org/10.1111/j.1875-595x.1998.tb00723.x.

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28

Lin, Louis, Melody Y. H. Chen, Domenico Ricucci, and Paul A. Rosenberg. "Guided Tissue Regeneration in Periapical Surgery." Journal of Endodontics 36, no. 4 (April 2010): 618–25. http://dx.doi.org/10.1016/j.joen.2009.12.012.

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29

Nyman, Sture. "Bone regeneration using the principle of guided tissue regeneration." Journal of Clinical Periodontology 18, no. 6 (July 1991): 494–98. http://dx.doi.org/10.1111/j.1600-051x.1991.tb02322.x.

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30

Petrović, Milica, Ljiljana Kesić, Radmila Obradović, Simona Stojanović, Branislava Stojković, Marija Bojović, Ivana Stanković, Kosta Todorović, Milan Spasić, and Nenad Stošić. "Regenerative periodontal therapy: I part." Acta stomatologica Naissi 37, no. 84 (2021): 2304–13. http://dx.doi.org/10.5937/asn2184304p.

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Introduction: Under the concept of regenerative periodontal therapy, there are two approaches: the first is the passive regeneration conceptthat includes bone substituents and guided periodontal regeneration by using of biomembranes and the second concept of active regeneration that impliesthe use of growth factors. The aim of the passive regeneration, by using of bone matrix (bone substituens) has been stabilization and bone defects management, preventing epithelial tissue growth, as well as saving space for the new tissue regeneration. This concept implies the use of autogenous transplantats, xenografts, allografts, as well as alloplastic materials. The carriers for active tissue regeneration, growth factors -GF are biological mediators that regulate cellular processes and that is crucial for the tissue regeneration. Aim:Presentation ofmodern approaches to periodontal therapy thatare focused on the attachment regeneration and complete reconstruction of periodontal tissue. Conclusion: In the future, periodontal regenerative therapy with periodontalligament progenitor cells should encourage repopulation of the areas that have been affected by periodontal disease.

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31

Bajpai, Devika. "Recent advances in GTR scaffolds." Bioinformation 18, no. 12 (December 31, 2022): 1181–85. http://dx.doi.org/10.6026/973206300181181.

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Periodontitis is a serious chronic inflammatory condition that can cause periodontal tissue deterioration and, eventually, tooth loss. Periodontal regenerative therapy using membranes and bone grafting materials, as well as flap debridement and/or flap curettage, have all been used with varying degrees of clinical effectiveness. Current resorbable and non-resorbable membranes serve as a physical barrier, preventing connective and epithelial tissue down growth into the defect and promoting periodontal tissue regeneration. The "perfect" membrane for use in periodontal regenerative therapy has yet to be created, as these conventional membranes have several structural, mechanical, and bio-functional constraints. We hypothesised in this narrative review that the next-generation of guided tissue and guided bone regeneration (GTR/GBR) membranes for periodontal tissue engineering will be a graded-biomaterials that closely mimics the extracellular matrix.

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Namanloo, Reza Abdollahi, Maedeh Ommani, Kamyar Abbasi, Mostafa Alam, Ashkan Badkoobeh, Mahdi Rahbar, Hadi Kokabi Arasteh, Emran Hajmohammadi, Reza Sayyad Soufdoost, and Seyed Ali Mosaddad. "Biomaterials in Guided Bone and Tissue Regenerations: An Update." Advances in Materials Science and Engineering 2022 (May 5, 2022): 1–14. http://dx.doi.org/10.1155/2022/2489399.

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Purpose. Guided tissue reconstruction can be performed to restore the supporting structure of a previously lost tooth, which, in addition to maintaining beauty, preserves the function of the tooth in the patient. Materials and Methods. In this review, Scopus, PubMed, and MEDLINE databases were searched using the keywords “biocompatible materials,” “membrane,” “bone regeneration,” “tissue reconstruction,” and “dental biomaterials.” Overall, 150 articles were reviewed, and finally, 107 articles published during 2000–2021 were included in the final paper. Results. Studies have been conducted on a variety of membranes in both clinical and experimental settings. The first half of this article explores the different kinds of membranes and diverse classes of biomaterials used in these procedures. Secondly, biomaterials are examined for their therapeutic uses such as growth factors, stem cells, and gene delivery vehicles. Conclusion. If a tooth has been extracted or if the gums have been infected with periodontal disease, guided bone regeneration procedures may be used to restore the lost bone. Recent years have seen a variety of approaches to regenerating these tissues. To prevent nonossifying cells from entering, membranes are heavily employed during guided rebuilding.

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Buser, D., U. Brägger, N. P. Lang, and S. Nyman. "Regeneration and enlargement of jaw bone using guided tissue regeneration." Clinical Oral Implants Research 1, no. 1 (December 1990): 22–32. http://dx.doi.org/10.1034/j.1600-0501.1990.010104.x.

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Sahu, Jigyasa, Deepti Rakesh Gattani, Rajvir Malik, Saurabh Lingala, and Nupur Kar. "MEMBRANES FOR GUIDED TISSUE REGENERATION - AN UPDATE." International Journal of Advanced Research 8, no. 7 (July 31, 2020): 1066–74. http://dx.doi.org/10.21474/ijar01/11369.

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Caffesse, Raul G., and William Becker. "Principles and Techniques of Guided Tissue Regeneration." Dental Clinics of North America 35, no. 3 (July 1991): 479–94. http://dx.doi.org/10.1016/s0011-8532(22)00852-7.

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Inuzuka, Akihiro, Toshiaki Shibutani, and Yukio Iwayama. "Effect of Bisphosphonate on Guided Tissue Regeneration." Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) 40, no. 1 (1998): 9–17. http://dx.doi.org/10.2329/perio.40.9.

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37

Agus Susanto, Susi Susanah, Bambang Pontjo, and Mieke Hemiawati Satari. "MEMBRAN GUIDED TISSUE REGENERATION UNTUK REGENERASI PERIODONTAL." Dentika Dental Journal 18, no. 3 (July 1, 2015): 300–304. http://dx.doi.org/10.32734/dentika.v18i3.1980.

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Berbagai teknik bedah dan bahan terus dikembangkan untuk meningkatkan regenerasi periodontal. Salah satu metode bedahyang sering digunakan pada defek periodontal adalah menggunakan barriermembranguided tissue regeneration (GTR) atauguided bone regeneration (GBR). Prinsip GTR/GBR adalah menggunakan barriermembran untuk menutupi tulang danligamen periodontal, kemudian memisahkannya sementara dari epitel gusi. Fungsi membran ini meningkatkan dan menjagabekuan darah dan bertindak sebagai scaffold untuk perlekatan dan proliferasi sel. Terdapat dua jenis membran yaitumembran non resorbable dan resorbable. Membran non resorbable pada umumnya terbuat dari polytetrafluoroethylene,membran ini sifatnya stabil, nondegradable dan biokompatibel, tetapi penggunaannya memerlukan bedah kedua untukmengambil membran. Membran resorbable berasal dari bahan sintetis seperti polyglycolic, polylactic acid dan bahan alamiseperti kolagen dan laminar bone. Pembuatan membran yang ideal masih terus dikembangkan, membran kolagen saat inilebih sering digunakan karena mempunyai biocompatibility yang optimal walaupun tingkat resorpsi membran sulit untukdiprediksi.

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38

Quin¯ones, Carlos R., and Raul G. Caffesse. "Current status of guided periodontal tissue regeneration." Periodontology 2000 9, no. 1 (October 1995): 55–68. http://dx.doi.org/10.1111/j.1600-0757.1995.tb00056.x.

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39

de Olyveira, Gabriel Molina, Márcio Luiz dos Santos, Ligia Maria Manzine Costa, Paula Braga Daltro, Pierre Basmaji, Gildásio de Cerqueira Daltro, and Antônio Carlos Guastaldi. "Bacterial Cellulose Biocomposites for Guided Tissue Regeneration." Science of Advanced Materials 6, no. 12 (December 1, 2014): 2673–78. http://dx.doi.org/10.1166/sam.2014.1985.

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40

Giardino, Roberto, Milena Fini, Nicolo Nicoli Aldini, Gianluca Giavaresi, and Michele Rocca. "Polylactide Bioabsorbable Polymers for Guided Tissue Regeneration." Journal of Trauma: Injury, Infection, and Critical Care 47, no. 2 (August 1999): 303–8. http://dx.doi.org/10.1097/00005373-199908000-00014.

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41

Tayebi, Lobat, Morteza Rasoulianboroujeni, Keyvan Moharamzadeh, Thafar K. D. Almela, Zhanfeng Cui, and Hua Ye. "3D-printed membrane for guided tissue regeneration." Materials Science and Engineering: C 84 (March 2018): 148–58. http://dx.doi.org/10.1016/j.msec.2017.11.027.

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42

Diedrich, Peter R. "Guided tissue regeneration associated with orthodontic therapy." Seminars in Orthodontics 2, no. 1 (March 1996): 39–45. http://dx.doi.org/10.1016/s1073-8746(96)80038-7.

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CORTELLINI, PIERPAOLO, and MAURIZIO S. TONETTI. "Focus on intrabony defects: guided tissue regeneration." Periodontology 2000 22, no. 1 (February 2000): 104–32. http://dx.doi.org/10.1034/j.1600-0757.2000.2220108.x.

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SANZ, MARIANO, and JEAN LOUIS GIOVANNOLI. "Focus on furcation defects: guided tissue regeneration." Periodontology 2000 22, no. 1 (February 2000): 169–89. http://dx.doi.org/10.1034/j.1600-0757.2000.2220111.x.

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JT, Mellonig, and Triplett RG. "Guided tissue regeneration and endosseous dental implants." Implant Dentistry 3, no. 1 (1994): 56. http://dx.doi.org/10.1097/00008505-199404000-00015.

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Nyman, Sture, Jan Gottlow, Jan Lindhe, Thorkild Karring, and Jan Wennstrom. "New attachment formation by guided tissue regeneration." Journal of Periodontal Research 22, no. 3 (May 1987): 252–54. http://dx.doi.org/10.1111/j.1600-0765.1987.tb01581.x.

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Zhang, Ben, and Jie Song. "3D-Printed Biomaterials for Guided Tissue Regeneration." Small Methods 2, no. 9 (January 22, 2018): 1700306. http://dx.doi.org/10.1002/smtd.201700306.

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Funakoshi, Eiji. "The application of guided tissue regeneration, guided bone regeneration and implants to periodontal treatment." Nihon Shishubyo Gakkai Kaishi (Journal of the Japanese Society of Periodontology) 40, Supplement1 (1998): 55. http://dx.doi.org/10.2329/perio.40.supplement1_55.

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Srinivasan, K. "Recent advances in periodontal regeneration – A review." Journal of the Indian Dental Association Tamil Nadu 14, no. 2 (2024): 1. http://dx.doi.org/10.26634/jidat.14.2.20135.

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Abstract:

Periodontal Disease (PD) is one of the most common inflammatory oral diseases, affecting approximately 47% of adults aged 30 years or older in the United States. If not treated properly, PD leads to degradation of periodontal tissues, causing tooth movement, and eventually tooth loss. Conventional clinical therapy for PD aims at eliminating infectious sources and reducing inflammation to arrest disease progression, which cannot achieve the regeneration of lost periodontal tissues. Over the past two decades, various regenerative periodontal therapies, such as Guided Tissue Regeneration (GTR), enamel matrix derivative, bone grafts, growth factor delivery, and the combination of cells and growth factors with matrix-based scaffolds, have been developed to target the restoration of lost tooth-supporting tissues, including the periodontal ligament, alveolar bone, and cementum. This review discusses recent progress in periodontal regeneration using tissue-engineering and regenerative medicine approaches. Specifically, the focus is on the advances in biomaterials and controlled drug delivery for periodontal regeneration in recent years. Special attention is given to the development of advanced bio-inspired scaffolding biomaterials and temporospatial control of multi-drug delivery for the regeneration of the cementum-periodontal ligament-alveolar bone complex. Challenges and future perspectives are presented to provide inspiration for the design and development of innovative biomaterials and delivery systems for new regenerative periodontal therapy.

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Malhotra, Ranjan, Anoop Kapoor, Vishakha Grover, Nitin Verma, and Jasjit Kaur Sahota. "Future of Periodontal Regeneration." Journal of Oral Health and Community Dentistry 4, Spl (2010): 38–47. http://dx.doi.org/10.5005/johcd-4-spl-38.

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ABSTRACT The management of periodontal defects has been an ongoing challenge in clinical periodontics. In the recent past, attention has been focused more on regenerative and reconstructive therapies i.e. bone grafts, guided tissue regeneration, root conditioning, polypeptide growth factors, rather than on respective therapies. These therapeutic measures are shown to be limited in the predictability of healing and regenerative response in the modern clinical practice because oral environment presents several complicating factors that border regeneration. The 21st century appears to represent a time in history when there is a convergence between clinical dentistry and medicine, human genetics, developmental and molecular biology, biotechnology, bioengineering, and bioinformatics, resulting in the emergence of novel regenerative therapeutic approaches viz. tissue engineering, gene therapy and RNA interference. The focus of this review paper is to furnish and update the current knowledge of periodontal tissue engineering, gene therapy and RNA interference i.e. the future of periodontal regeneration.

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