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1

Jafari, Elmira, and Carola Hein. "Tehran’s Decentralization Project and the Emergence of Socio-Spatial Boundaries." International Journal of Islamic Architecture 11, no. 1 (January 1, 2022): 45–71. http://dx.doi.org/10.1386/ijia_00064_1.

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In 1966, the government-sponsored Plan Organization commissioned the first Tehran Master Plan (TMP), setting the stage for the Iranian capital’s extensive transformation and its spatial and social re-structuring. In the process, Abdolaziz Farmanfarmaian, an Iranian architect, collaborated with Victor Gruen Associates of the United States to implement lessons from Gruen’s urban model, the ‘Cellular Metropolis of Tomorrow’, in a reorganization of the socio-spatial structure of Tehran. After a three-year study of the city’s socio-economic and physical organization, the planners proposed decentralization of the congested old city centre and the development of new ‘modern’ centres of activity along a rapid transit line extending westward. This article engages with ongoing discourses on inclusive cities and reflects upon the segregating effects of boundary-edges to argue that the planners’ emphasis on locating urban facilities in the centre of communities led them to ignore emerging dead edges between socially divided neighbourhoods, ultimately hindering social interactions. The allocation of these edges to urban infrastructure, highways, urban voids, and large green spaces isolated and insulated each community from the larger urban area. Through the analysis of the TMP’s reports, this article reveals how the modernist planners mediated the creation of socio-physical boundaries, segmented the city, and increased social exclusivity.
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Zuccaro Marchi, Leonardo. "Victor Gruen: the environmental Heart." Journal of Public Space 2, no. 2 (October 11, 2017): 75. http://dx.doi.org/10.5204/jps.v2i2.94.

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<p>Victor Gruen is the pioneer of the regional shopping centre, he is the “Mall Maker”, which, is also the title of a book by M. Jeffrey Hartwick about this Austrian-born architect. Well known for his first commercial projects, which have been copied and analysed worldwide, mostly negatively influencing the structure of cities and societies, Gruen had focused his attention on the importance of the environmental crisis in his both theoretical writings and projects as early as the 1960s. How can Gruen be personified as both the “Mall Maker” and the “Architect of the Environment’? In the early 1970s Gruen presented Die Charta von Wien, as an attempt to readapt the CIAM`s Charte d`Athenes to the contemporary conditions, with a brand new emphasis on the ecological environment as well. This paper will deal mainly with these contradictions and synergies between “consumeristic” architecture and its role in the city in relation to the environmental issues posed by its inventor. The complexity of the connections between consumerism and ecology and the references to CIAM and Gruen, appear to be important themes for a discussion on public space and our contemporary urban condition.</p>
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Hill, David R. "Sustainability, Victor Gruen, and the Cellular Metropolis." Journal of the American Planning Association 58, no. 3 (September 30, 1992): 312–26. http://dx.doi.org/10.1080/01944369208975810.

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4

Zuccaro Marchi, Leonardo. "Redeeming the shopping center. Victor Gruen's ideal cellular metropolis and Louvain-la-Neuve." TERRITORIO, no. 96 (September 2021): 159–73. http://dx.doi.org/10.3280/tr2021-096015.

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The ‘mall maker' Victor Gruen is well known as the architect who played a dominant role in the design and global proliferation of the shopping mall. While many recent publications already highlighted and re-evaluated the architectural importance of Gruen's shopping center, the urban ideal/utopian projects proposed by Gruen have not been considered in depth thus far. Gruen mixed his design principles for shopping centers with ecological interpretations, proposing the Cellular Metropolis as a new urban utopia. This paper aims to shed light on Gruen's urban ideas, from his critical idea of the ecological-commercial realm to the study of radical commercial hybridizations, which are still relevant lessons for the design of our socio-spatial contemporary condition. In particular, the article focuses on the case study of Louvain-la-Neuve to ground such ideas into a real site.
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5

Styhre, Alexander. "The invention of the shopping mall." Journal of Engineering, Design and Technology 17, no. 2 (April 1, 2019): 283–99. http://dx.doi.org/10.1108/jedt-08-2018-0139.

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Purpose The economic system of competitive capitalism strives toward liquid markets wherein the cost for transacting is minimized. Liquidity is mostly addressed in association with abstract markets (e.g. the securities market), but also consumer markets are determined by liquidity concerns. The purpose of this paper is to examine the shopping mall concept, developed by the architect and social reformer Victor Gruen during the early 1950s, as a form of production of capitalist space, intended to reduce transaction costs. As an auxiliary benefit, Gruen envisioned the shopping mall as a cultural and civic center in the midst of the satellite town of suburbia, the new site of urban expansion during the post-war boom decades. Design/methodology/approach The paper reviews secondary literature on the historical development of the shopping mall as a consumer space. In addition, relevant economic and social science literature is referenced. Findings The architecture, design, ornamentation and day-to-day management of the shopping mall were premised on a consumerist way of life, ultimately serving as an all-too-visual index of the triumph of competitive capitalism in the cold war era. However, Gruen’s accomplishments were gradually compromised by the interest of money-minded developers and construction industry actors, and the shopping mall arguably never fulfilled the social and cultural function that Gruen anticipated. Regardless of such outcomes, the production of capitalist space as scripted by Gruen is still determining everyday life in consumer society, making Gruen a key figure, albeit only limitedly recognized, in the history of late modern society and in the capitalist economy. Originality/value The paper emphasizes the role of Victor Gruen in the post-Second World War period, being one of the most influential practitioners and social reformers in the era. Furthermore, the paper stresses how market liquidity is a key concern in Gruen’s project to create a communal space for the American suburban population in the era of the expanding welfare state.
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6

Fishman, Aleisa. "Mall Maker: Victor Gruen, Architect of an American Dream." History: Reviews of New Books 33, no. 1 (January 2004): 9. http://dx.doi.org/10.1080/03612759.2004.10526370.

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7

Mennel, Timothy. "Victor Gruen and the Construction of Cold War Utopias." Journal of Planning History 3, no. 2 (May 2004): 116–50. http://dx.doi.org/10.1177/1538513204264755.

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8

Smiley, David. "Mall Maker: Victor Gruen, Architect of an American Dream - Edited by M. Jeff Hardwick and Victor Gruen: From Urban Shop to New City - Edited by Alex Wall." Journal of Architectural Education 62, no. 1 (September 2008): 76–78. http://dx.doi.org/10.1111/j.1531-314x.2008.00226.x.

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9

Garvin, Alexander. "Mall Maker: Victor Gruen, Architect of an American Dream. M. Jeffrey Hardwick." Archives of American Art Journal 43, no. 3/4 (January 2003): 27–28. http://dx.doi.org/10.1086/aaa.43.3_4.1557802.

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10

Ozuduru, Burcu H. "Review: Shopping Town: Designing the City in Suburban America by Victor Gruen and Anette Baldauf, eds." Journal of Planning Education and Research 40, no. 4 (January 17, 2019): 494–95. http://dx.doi.org/10.1177/0739456x18822110.

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11

Hill, David R. "A case for teleological Urban form history and ideas: Lewis Mumford, F.L. Wright, Jane Jacobs and Victor Gruen." Planning Perspectives 8, no. 1 (January 1993): 53–71. http://dx.doi.org/10.1080/02665439308725763.

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12

Gregg, Kelly. "Conceptualizing the pedestrian mall in post-war North America and understanding its transatlantic transfer through the work and influence of Victor Gruen." Planning Perspectives 34, no. 4 (March 8, 2018): 551–77. http://dx.doi.org/10.1080/02665433.2018.1437555.

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13

Bloom, Nicholas Dagen. "M. Jeffrey Hardwick, Mall Maker: Victor Gruen, Architect of an American Dream. Philadelphia: University of Pennsylvania Press, 2004. 288pp. 47 plates. £16.50/$24.95." Urban History 38, no. 1 (April 5, 2011): 199–200. http://dx.doi.org/10.1017/s0963926811000307.

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14

Hewitt, Ashley, and Eric Beauregard. "Offender Mobility During the Crime: Investigating the Variability of Crime Event Contexts and Associated Outcomes in Stranger Sexual Assaults." Sexual Abuse 29, no. 4 (July 10, 2015): 313–41. http://dx.doi.org/10.1177/1079063215594377.

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Using data from qualitative interviews and police reports, latent class analysis is used on a sample of 54 repeat stranger sexual offenders who committed 204 sexual assaults to identify discrete contexts present at the time of victim encounter that influence these offenders’ decision to use more than one location to commit their crimes. Five distinct classes are identified: residential outdoor common area, spontaneous/quiet outdoor site, residential home, active green space, and indoor/public gathering place. An investigation into the outcome(s) that most often result from the offender’s decision to move the victim during the sexual assault indicates that those who move the victim from an active green space overwhelmingly engage in sexual penetration, as well as forcing their victims to commit sexual acts on them. Crimes where the victim is moved from a residential home show evidence of the offender physically harming the victim as well as using more force than necessary to complete the assault. Implications for situational crime prevention are discussed.
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Gruen, J. Philip. "Merchant of Illusion: James Rouse, America's Salesman of the Businessman's Utopia Nicholas Dagen Bloom Mall Maker: Victor Gruen, Architect of an American Dream M. Jeffrey Hardwick." Journal of the Society of Architectural Historians 64, no. 3 (September 2005): 390–93. http://dx.doi.org/10.2307/25068182.

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Dyer, Stephanie. "M. Jeffrey Hardwick. Mall Maker: Victor Gruen, Architect of an American Dream. Philadelphia: University of Pennsylvania Press, 2003. 288 pp. ISBN 0-8122-3762-5, $29.95." Enterprise & Society 5, no. 2 (June 2004): 345–46. http://dx.doi.org/10.1017/s1467222700013689.

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Dyer, S. "M. Jeffrey Hardwick. Mall Maker: Victor Gruen, Architect of an American Dream. Philadelphia: University of Pennsylvania Press, 2003. 288 pp. ISBN 0-8122-3762-5, $29.95." Enterprise and Society 5, no. 2 (June 1, 2004): 345–46. http://dx.doi.org/10.1093/es/khh051.

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18

Crespo-Fajardo, José Luis, Geovanny Sagbay-Jaramillo, and Luisa Pillacela-Chin. "Conversando con… Luis Longhi." EGA Revista de Expresión Gráfica Arquitectónica 26, no. 41 (March 24, 2021): 131. http://dx.doi.org/10.4995/ega.2021.15234.

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<p>Luis Longhi Traverso, catedrático de la Universidad Peruana de Ciencias Aplicadas (UPC) y conferencista internacional, nos recibe una tarde de septiembre a través de videollamada. Estamos ante uno de los arquitectos con mayor proyección del Perú. En las últimas décadas su figura ha sido ampliamente reconocida y sus proyectos le han valido importantes galardones, destacando el Hexágono de Oro 2010, la mayor distinción de la arquitectura peruana. Licenciado por la Universidad Ricardo Palma y con estudios de posgrado en la Universidad de Pennsylvania, trabajó en el estudio de Balkrishna Doshi en Amhedabad (India). En Estados Unidos se desempeñó en las oficinas de Adèle Santos, David Slovic, Gruen Associates y Farrington Design Group, entre otras. En 1994 regresó a Perú para crear la firma <em>Longhi Architects</em>, centrada en realizar arquitecturas con un alto grado de sentido artístico.</p><p><em> </em></p><p>Un ejemplo es la casa donde actualmente reside y desde la que nos recibe virtualmente: la Casa Chullpas (afueras de Lima), cuyas estructuras tubulares se relacionan con los restos arqueológicos incas de las chullpas de Sillustani, en Puno, su lugar de nacimiento. El interior de la casa Chullpas está lleno de esculturas, unas propias, las más abstractas, y otras de cariz precolombino. Las maquetas de cartón y madera nos recuerdan su oficio docente, en tanto los carteles anunciadores de representaciones teatrales hablan de la época en que ejerció como escenógrafo. Entre piedras y el gris hormigón pintado de tonos magentas, amarillos y azules, el <em>Inca Longhi</em>, como le llaman sus amigos, ha pasado este tiempo de confinamiento.</p>
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Bee, Robert L. ": The Primal Mind . ; Native Land: Nomads of the Dawn . ; Spirit of the Hunt . Thomas Howe Associates. ; Itam Hakin, Hopiit . Victor Masayesva." American Anthropologist 90, no. 1 (March 1988): 235–37. http://dx.doi.org/10.1525/aa.1988.90.1.02a00970.

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20

Longstreth, Richard. "Mall Maker: Victor Gruen, Architect of an American Dream. By M. Jeffrey Hardwick. Philadelphia: University of Pennsylvania Press, 2003. 268 pp. Illustrations, notes, index. Cloth, $29.95. ISBN 0-812-23762-5." Business History Review 78, no. 1 (2004): 142–44. http://dx.doi.org/10.2307/25096847.

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21

Rimmer, Douglas. "Current Research at the Centre of West African Studies, University of Birmingham." African Research & Documentation 39 (1985): 41–44. http://dx.doi.org/10.1017/s0305862x0000830x.

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The Centre of West African Studies was established at Birmingham in 1963 as an interdisciplinary department of area studies primarily engaged in research and postgraduate teaching. Academic appointments have been made ito the Centre in the social sciences and the humanities. A few members of other departments who are closely concerned with African studies have become Associates of the Centre.To date nearly 80 research theses have been completed in the Centre (a list is obtainable from Mrs. E. de Veer, CWAS, University of Birmingham, P.O. Box 363, Birmingham B15 2TT). Those submitted and approved in the last year (1984-85) were on the history of the cocoa industry in the Amansie district of Asante (G.M. Austin), the political transformation and ethnic unification of the Tarok (Yergam) from the 19th Century toe. 1954 (Stephen Banfa), Nigerian clerical workers (a sociological study by Victor Omogbehin), Nigeria, the West and Southern Africa, 1960-83 (Adaye Orugbani), and the economy and society of St. Louis du Senegal, 1659-1809, with special reference to the influence of Eurafricans (S.O.M. Zilombo).
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Wetherell, Sam. "Victor Gruen and Anette Baldauf (eds.), Shopping Town: Designing the City in Suburban America. Minneapolis: Minnesota University Press, 2017. 328pp. 71 b&w photos, 7 x 10. $120.00 hbk. $29.25 pbk." Urban History 46, no. 3 (July 11, 2019): 575–76. http://dx.doi.org/10.1017/s096392681900052x.

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23

Heinrich, Adam. "The Archaeology of Morris Cohen: A Jewish Farmer’s Victory over a Groundhog in Nineteenth-Century Green Brook, New Jersey." New Jersey Studies: An Interdisciplinary Journal 7, no. 2 (July 22, 2021): 108–31. http://dx.doi.org/10.14713/njs.v7i2.252.

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Excavations at the Vermeule-Mundy House uncovered a rich artifact deposit dating to the mid-1860s. The artifacts can be associated with Morris Cohen, an early Jewish farmer to settle in rural New Jersey, where he raised a family, a range of animals, and grains, and produced a large amount of butter. In an effort to deter a groundhog from burrowing under their porch, the Cohens placed hundreds of ceramic, glass, and iron objects into the burrow. These artifacts provide information about their table settings and agricultural production, and they may provide details about Cohen’s socioeconomic status as well as his Jewish ethnicity through the use of multiple ceramic and glass sets as well as a preference for olive oil.
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Bezruchko, Oleksandr, and Volodymyr Myslavskyi. "Development of the adventure genre in Ukrainian cinema in the second half of the twenties of the twentieth century." Culturology Ideas, no. 21 (1'2022) (2021): 159–67. http://dx.doi.org/10.37627/2311-9489-21-2022-1.159-167.

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Our research is based on a wide range of little-known publications in the Ukrainian and Russian periodicals 1922–1930. In this article we analyze the development of the adventure genre in Ukrainian cinema in the second half of the twenties of the twentieth century. Winners define history. The making of adventure films about the Civil War (Soviet-Ukrainian war (1917–1921)) in Ukraine by specialists of the All-Ukrainian Cinema and Photo Administration was associated with the persistent attempts of the Soviet government to rewrite the real history of the struggle of the Ukrainian people for the desired independence and their own statehood in 1917–1921 into a falsified "film history". However, these films were made mainly according to the simplified scheme of the popular at that time "kinoagitka" (propaganda films), where there were schematic "white", "red", "green", Makhnovists, white rear, red underground, struggle and victory.
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Bolton, Brenda. "Signs, Wonders, Miracles: Supporting the Faith in Medieval Rome." Studies in Church History 41 (2005): 157–78. http://dx.doi.org/10.1017/s042420840000019x.

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Judging by the quantity of surviving texts – whether vitae or saints’ lives, libelli miraculorum or narratives of miracles for public reading in church, lectionaries or collections of liturgical readings, inventiones and translationes or accounts of relics found and later moved to a new location, popular receptivity to signs, wonders and miracles had reached a high point by the turn of the twelfth century. Whilst ordinary laypeople remained fascinated by supernatural phenomena, intellectuals were already beginning to challenge the preternatural in a process described by Chenu as the ‘desacralizing’ of nature. In the first book of his treatise, De Sanctis et eorum pignoribus (c.1120), Guibert, Abbot of Nogent, had contrasted the credulity of the faithful towards pseudo-miracles with the growing unease experienced by many scholars at inadequate written evidence for the authentication of relics. Andrew of Saint-Victor (d.1175), in an exposition on the literal interpretation of Scripture, found himself arguing for a natural explanation of events before any recourse to the miraculous. In the School of Pastoral Theology at Paris, Master Peter the Chanter (d.1197) vehemently criticized trial by ordeal as a flagrant tempting of God whereby a supposedly miraculous intervention was allowed to intrude into the regular legalistic operation of the courts. In the years immediately following the Chanter’s death, his former students, led by Pope Innocent III (1198–1216) and like-minded clerical associates, developed a significant agenda, emphasizing rationality and record keeping to sustain the faith of the Church within a new and more firmly pastoral context.
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Villalta, O. N., W. S. Washington, G. M. Rimmington, and W. E. MacHardy. "Environmental factors influencing maturation and release of ascospores of Venturia pirina in Victoria, Australia." Australian Journal of Agricultural Research 52, no. 8 (2001): 825. http://dx.doi.org/10.1071/ar00093.

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The influence of moisture, light, and temperature on Venturia pirina ascospore maturation and discharge was studied during 1992–99 in 2 pear-growing regions in Victoria. In each year and site, mature ascospores were trapped over a 3-month period beginning a few days before or at the green-tip stage of pear tree development in early September and ending in late November, with the majority of ascospores ((>80%) trapped between green-tip and petal-fall. Ascospore discharge was associated with rain and dew, with 90–98% of the season’s total number of ascospores trapped during rain events and 2–10% trapped during dew events in the 12 data sets examined. Most ascospores were trapped (82.5– 99.9%) during daytime (0600–1800 hours). The 0.1–17.5% of ascospores detected during night time (1900–0500 hours) were trapped mainly within 1–3 h of dawn or dusk. There were linear relationships between the logit of cumulative percentage of ascospore maturation and temperature accumulation (above 0 degree-days), calculated both daily and for days with >= 0.2 mm of rainfall. Six linear regression equations were formulated with 10 years of field data and using the 2 methods of accumulating degree-days, to predict the cumulative percentage of matured ascospores. Predictions were compared with additional field and laboratory observations not used in the formulation of the linear equations. The importance of the temperature-based linear equations is discussed in relation to the prediction of pear scab ascospore maturity for use in a pear scab management program.
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Lever, James, Robert Brkljača, Gerald Kraft, and Sylvia Urban. "Natural Products of Marine Macroalgae from South Eastern Australia, with Emphasis on the Port Phillip Bay and Heads Regions of Victoria." Marine Drugs 18, no. 3 (February 28, 2020): 142. http://dx.doi.org/10.3390/md18030142.

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Marine macroalgae occurring in the south eastern region of Victoria, Australia, consisting of Port Phillip Bay and the heads entering the bay, is the focus of this review. This area is home to approximately 200 different species of macroalgae, representing the three major phyla of the green algae (Chlorophyta), brown algae (Ochrophyta) and the red algae (Rhodophyta), respectively. Over almost 50 years, the species of macroalgae associated and occurring within this area have resulted in the identification of a number of different types of secondary metabolites including terpenoids, sterols/steroids, phenolic acids, phenols, lipids/polyenes, pheromones, xanthophylls and phloroglucinols. Many of these compounds have subsequently displayed a variety of bioactivities. A systematic description of the compound classes and their associated bioactivities from marine macroalgae found within this region is presented.
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Мороз, B., and Д. Щепова. "VK YAKUNIN SCIENTIFIC, PUBLIC AND POLITICAL ACTOR OF HOURS "REBUILDING" AND REFORMING OF THE UKRAINIAN SOCIETY ON THE FOREIGN AFFAIRS." Problems of Political History of Ukraine, no. 15 (February 5, 2020): 30–33. http://dx.doi.org/10.33287/11923.

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The scientific and social and political views of Doctor of Historical Sciences, Professor Yakunin Victor Kuzmich are considered. Emphasis is placed on his principled position in attitude to the «truth of history», the honesty and decency of scientific research. In the article shows that the main focus of his work was the fight against chauvinism and refined nationalism.The content and essence of universal categories «patriotic», «national» and «nationalistic» are revealed. Based on primary sources comprehends the contribution of historians of the Soviet period and Ukrainian scholars of the post-Soviet times to the study of the history of the OUN and the UIM. The analysis of socio-political phenomena and socio-cultural phenomena of patriotism and nationalism in their historical development is given.His scientific works «History, Ideology, Politics», «The CPSU collapse», «Patriotism and Nationalism: Experience and Lessons in History», «OUN Ideology: History and Modernity» and others testify to the author’s principle, thoroughness and talent. His language, manner of describing various historical events and factors is almost unmatched. His scientific works are easy to read and admire. V. K. Yakunin in his scientific works analyzes the views of historians who disagree with him and have opposite visions of the «truth of history». He agrees with some points of criticism of the author, but by principles he gives his arguments and evidence. This is the truth and power of the Ukrainian scientist since the restructuring and reform of public relations in Ukraine. The article draws attention to the poor health of the professor, that he underwent heart surgery. Emphasis is placed on the support of V.K. Yakunin by colleagues and associates.
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Costa, Jamille Oliveira, Felipe J. Aidar, Juliana Santos Barbosa, Luciana Vieira Sousa Alves, Victor Batista Oliveira, Larissa Marina Santana Mendonça de Oliveira, Raysa Manuelle Santos Rocha, et al. "BALANCE Dietary Index in Patients with Heart Failure, and Its Adherence in Sergipe, Brazil." Clinics and Practice 12, no. 3 (May 31, 2022): 383–95. http://dx.doi.org/10.3390/clinpract12030043.

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Background: “The effective treatment of Heart Failure (HF) involves care with food intake. Recently, the Ministry of Health created the Brazilian Cardioprotective Diet and its dietary index, BALANCE, which assesses adherence to the standard’s recommendations”. Methods: This observational prospective study is part of the Congestive Heart Failure Registry (VICTIM-CHF) of Aracaju/SE. Observations and data collection took place from April 2018 to February 2021. Sociodemographic and clinical aspects and food consumption were evaluated. Food intake was determined using the food frequency questionnaire. Foods were categorized using the BALANCE dietary index into green, yellow, blue and red food groups. The BALANCE dietary index was obtained using median and interquartile ranges, scores of the Mann–Whitney U test, and associations between clinical variables and the index, through linear regression. Results: Participants included 240 patients with HF (61.12 ± 1.06 years), who were assisted by the Unified Health System (67.5%). Individuals with a partner showed greater adherence to the green food group recommendations (0.09; 0.00–0.17). The lowest adherence to recommendations regarding the blue food group was observed in individuals with excess weight, who had a higher consumption of foods rich in animal protein (0.54; 0.38–0.78). As for the red food group (ultra-processed foods) the highest adherence was observed by patients with diabetes mellitus (0.41; 0.05–0.77). The greatest adherence to the yellow food group, and a higher score, was observed in patients with the smallest left ventricular systolic diameter (LVSD). Conclusions: Being married was directly associated with the consumption of foods in the green group, while being overweight and having diabetes were inversely associated with adherence to the blue and red food groups, respectively. Greater adherence to the yellow food group recommendations was inversely associated with less change in the DSFVE.
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Yang, Hexiong, Tommy Yong, and Robert T. Downs. "Ferrobobfergusonite, □Na2Fe2+5Fe3+Al(PO4)6, a new mineral of the bobfergusonite group from the Victory Mine, Custer County, South Dakota, USA." Canadian Mineralogist 59, no. 3 (May 1, 2021): 617–27. http://dx.doi.org/10.3749/canmin.2000064.

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ABSTRACT A new mineral species, ferrobobfergusonite, ideally □Na2Fe2+5Fe3+Al(PO4)6, has been found in the Victory Mine, Custer County, South Dakota, USA. It is massive and associated with ferrowyllieite, schorl, fillowite, arrojadite, quartz, and muscovite. Broken pieces of ferrobobfergusonite are blocky or tabular with single crystals up to 0.9 × 0.7 × 0.4 mm. No twinning or parting is observed macroscopically. The mineral is deep green-brown and transparent with a pale green-yellow streak and vitreous luster. It is brittle and has a Mohs hardness of ∼5, with perfect cleavage on {010}. The measured and calculated densities are 3.68(1) and 3.69 g/cm3, respectively. Optically, ferrobobfergusonite is biaxial (+), with α = 1.698 (2), β = 1.705 (2), γ = 1.727 (2) (white light), 2V (meas.) = 65(2)°, 2V (calc.) = 60°, with orientation of the optic axes α ∧ X = 16°, β = Y, with X = yellowish brown, Y = brown, and Z = deep brown. The dispersion is very strong with r &gt; v. The calculated compatibility index based on the empirical formula is 0.017 (superior). An electron microprobe analysis yielded an empirical formula (based on 24 O apfu) of (Na1.72□1.28)Σ3.00(Fe2+3.50Mn0.89Mg0.44Ca0.13)Σ4.96(Fe3+0.77Al0.23)Σ1.00Al(PO4)6. Ferrobobfergusonite is isostructural with bobfergusonite, a member of the alluaudite supergroup. It is monoclinic, with space group P21/n and unit-cell parameters a = 12.7156(3), b = 12.3808(3), c = 10.9347(3) Å, β = 97.3320(10)°, and V = 1707.37(7) Å3. The crystal structure of ferrobobfergusonite contains six octahedral M (= Fe2+, Mg, Mn2+, Al, Fe3+) sites and five X (= Na, Mn2+, Ca) sites with coordination numbers between 6 and 8. The six MO6 octahedra share edges to form two types of kinked chains extending along [101], with one consisting of M1–M4–M5 linkages and the other of M2–M3–M6 linkages. These chains are joined by PO4 tetrahedra to form sheets parallel to (010), which are linked together through corner-sharing between PO4 tetrahedra and MO6 octahedra in the adjacent sheets, leaving open channels parallel to a, where the large X cations are situated. The M cations are strongly ordered over the six sites, with M1, M2, M3, and M4 being dominantly occupied by Fe2+, and M5 and M6 by Fe3+ and Al, respectively. Among the five X sites, the X1 site is filled with Mn2+ and Ca, whereas the X2–X5 sites are partially occupied by Na.
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Hogendorp, Brian K., and Raymond A. Cloyd. "Effect of Potassium Bicarbonate (MilStop®) and Insecticides on the Citrus Mealybug, Planococcus citri (Risso), and the Natural Enemies Leptomastix dactylopii (Howard) and Cryptolaemus montrouzieri (Mulsant)." HortScience 48, no. 12 (December 2013): 1513–17. http://dx.doi.org/10.21273/hortsci.48.12.1513.

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Both laboratory and greenhouse experiments were conducted to determine if the fungicide, MilStop® (BioWorks, Victor, NY), which contains the active ingredient, potassium bicarbonate, has direct activity on the citrus mealybug, Planococcus citri Risso. Spray applications of four different rates (4.5, 5.9, 7.4, and 14.9 g·L–1) were applied to green coleus, Solenostemon scutellarioides (L.) Codd., plants infested with citrus mealybugs. In addition, experiments were conducted to assess both the direct and indirect effects of MilStop® on two natural enemies of the citrus mealybug: the parasitoid, Leptomastix dactylopii (Howard), and the coccinellid beetle, Cryptolaemus montrouzieri (Mulsant). MilStop® provided between 56% and 86% mortality of citrus mealybug; however, the highest rate (14.9 g·L–1) was phytotoxic to coleus plants. Percent mortality associated with the second highest rate (7.4 g·L–1) was 82%, which was comparable to acetamiprid (84%) applied at 0.05 g·L–1. For the natural enemies, MilStop® treatment rates of 1.5 and 3.5 g·L–1 resulted in 16% mortality, whereas the 5.5- and 9.0-g·L–1 rates resulted in 33% mortality of L. dactylopii adults. MilStop® treatment rates of 3.5, 5.5, 9.0, and 12.0 g·L–1 resulted in 30%, 60%, 40%, and 90% mortality, respectively, of C. montrouzieri adults. Therefore, depending on the application rate, this fungicide may inadvertently kill citrus mealybugs when used to control fungal plant pathogens. It should not disrupt biological control programs targeting citrus mealybug in greenhouses that involve releases of L. dactylopii when used at low application rates, whereas MilStop® applications should be properly timed when using C. montrouzieri.
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A S, Vasudevan. "The Future of Work is a ‘Work in Progress’." NHRD Network Journal 13, no. 4 (October 2020): 454–63. http://dx.doi.org/10.1177/2631454120968950.

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This article is a phenomenological interpretation of the myriad processes that influence the transient nature of ‘work’ and measures to retrieve the dignity it deserves. Vasu is an emerging organisational futurist whose passion is to develop management educational approaches that ensure a positive outlook of the uncertain future ahead. The differences between Eastern and Western history, especially Indian history is ingrained with a unique resilience to catastrophic events, invasions and embedded diversity. Leaning more in defence of human dignity at work according to Pablo Gilbert, Victor Frankl, World Happiness Report 2012 and the contemporary theory of autopoiesis, he conjectures a ‘FUTOPIA’ rising in the horizon, where humanistic valuing of work becomes culture. The corporate world is realizing the shifting paradigms—from end goals of profit-centric strategies and exploitation of human futures to partnerships with associates and ‘working resources’ that optimize creative contribution from work environments. At a meta level, the nation-building agenda of development is talking the language of equal opportunity for and treatment of women at work, with equitable wage parity and abolition of forced labour in the United States. Recent bills in the Indian Parliament on education and farmers’ rights and tailoring of the archaic labour laws will strengthen the negotiation for equitable fund allocation. The spirit of enterprise will boost small and medium sectors, especially farming and food product preservation, innovation and research and development (R&D), and rapid skill development will for sure retrieve the dignity tag for academics, farm labourers and those in the service sector, such as paramedics, the police, etc. According to thought leaders, corporate founders and contemporary authors, the future of work can be seen as a promising work in progress towards a new work ethic. This article risks suggesting radical steps needed in challenging traditional leadership styles and human resource (HR) practices of a growth economy that draws on patriarchal alpha-male prominence. What will replace traditional leadership styles is compassionate servant leadership, with leaders who will become designers of future ‘work’ environments.
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Birrell, H. A., and R. L. Thompson. "Effect of environmental factors on the growth of grazed pasture in south-western Victoria." Australian Journal of Experimental Agriculture 46, no. 4 (2006): 545. http://dx.doi.org/10.1071/ea03048.

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This paper presents work from several studies on pasture production that were conducted in south-west Victoria at the Pastoral Research Institute, Hamilton. The frequency with which pasture growth commenced for each week of autumn in the years from 1965 to 1991 was assessed. The median period for the commencement of growth was in the third week of March (although the average date was March 27). Autumn data from several trials conducted over 3 decades were collated and analysed. A relationship between the grazed pasture yield (average of stocking rates plots) at the end of autumn and the rainfall showed that 200 mm of rainfall in the 3 months to the end of May was optimal while higher rainfall depressed the growth. The average daily growth rates of introduced pasture (perennial rye grass, Lolium perenne L. cv. Victorian, phalaris, Phalaris aquatica L. cv. Australian, subterranean clover Trifolium subterranneum L. and volunteer species) were measured in 2- and 4-week growth periods (G 2 and G 4, kg DM/ha.day) for the seasonal growth cycles over 4 years (1980–84 except 1983) when grazed by Merino wether sheep at stocking rates of 10, 13 or 18 sheep/ha. The rainfall throughout the study was lower than normal. Although differences in the animal performance between the stocking rates were only small, at the low stocking rate capeweed (Arctotheca calendula L.) in patches became the major component of the sward. Greater variation in G 2 than in G 4 indicated that growth responded quickly to current environmental conditions. A nonlinear regression accounted for 74% of the variance in G 2 when related to the 3 climatic factors of daylength, soil temperature at 10 cm depth and the soil moisture to a depth of 10 cm, and a plant factor of green herbage yield. The 26 % of unaccounted variance appears to be associated with an effect of stocking rate, possibly botanical composition. The botanical composition was not continuously monitored hence the only sward character included in the investigation was herbage yield. Comparison of the patterns of pasture growth from different latitudes indicated that while the growth pattern in south-western Victoria is erratic, it is intermediary between Mediterranean and temperate pasture types. Understanding this aspect has implications for improving the efficiency of animal production in this environment.
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Tobisu, Mamoru, Naoto Chatani, and Victor Snieckus. "Cluster Preface: C–O And Related Bond Activation." Synlett 28, no. 19 (November 20, 2017): 2559–60. http://dx.doi.org/10.1055/s-0036-1592031.

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Mamoru Tobisu received his PhD from Osaka University under the direction of Prof. Shinji Murai (2001). During his PhD studies, he was a visiting scientist (1999) with Prof. Gregory C. Fu at MIT. Following a period as a scientist at the Takeda Pharmaceutical Company (2001–2005), he started his academic career at Osaka University in 2005 as an assistant professor with Prof. Naoto Chatani. He was then appointed as an associate professor at the Center for Atomic and Molecular Technologies at Osaka University (2011) and was promoted to full professor at the Department of Applied Chemistry of Osaka University (2017). He received the Thieme Chemistry Journals Award (2008), the Chemical Society of Japan Award for Young Chemists (2009), the Young Scientists’ Award, a Commendation for Science and Technology from the Minister of Education, Culture, Sports, Science and Technology (2012), the Merck-Banyu Lectureship Award (2012), Thomson Reuters Research Front Award (2016), and the Mukaiyama Award (2018). Naoto Chatani received his PhD in 1984 under Professors Noboru Sonoda and Shinji Murai. In 1984, he joined the Institute of Scientific and Industrial Research at Osaka University as an Assistant Professor in the laboratory of Professor Terukiyo Hanafusa. After postdoctoral studies (1988–1989 under Professor Scott E. Denmark at the University of Illinois, Urbana-Champaign), he moved back to Osaka University and was promoted to the rank of Associate Professor (1992) and to Full Professor (2003). He is a recipient of The Chemical Society of Japan Award for Young Chemists (1990), The Green & Sustainable Chemistry Award from the Minister of Education, Culture, Sports, Science and Technology (2005), the Nagoya Silver Medal (2013), The Chemical Society of Japan Award (2017), a Humboldt Research Award (2017), a Clarivate Analytics Highly Cited Researcher (2017) and will be a recipient of an Arthur C. Cope Scholar Award (2018). Victor Snieckus was born in Kaunas, Lithuania and spent his childhood in Germany during World War II. He received training at U. Alberta, Canada, (B.Sc.), U. California, Berkeley (M.Sc. D.S. Noyce), and U. Oregon (Ph.D. Virgil Boekelheide). He returned to his adopted country for postdoctoral studies (National Research Council, Ottawa, Ted Edwards). Appointments: U. of Waterloo, Assistant (1966) to Professor (1979); Monsanto/NRC Industrial Research Chair, 1992–1998; Queen’s University, Inaugural Bader Chair in Organic Chemistry (1998–2009); Bader Chair Emeritus and Director, Snieckus Innovations, 2009-. Selective awards: A.C. Cope Scholar (2001, one of 5 Canadians), Order of the Grand Duke Gediminas (2002, from the President of Lithuania), Arvedson-Schlenk (2003, Gesellschaft Deutscher Chemiker), Bernard Belleau (2005, Canadian Society for Chemistry), Givaudan-Karrer Medal (2008, U. Zurich), Honoris causa (2009, Technical U. Tallinn, Estonia), Global Lithuanian Award (2012), Yoshida Lectureship (2017). He hopes that he has only temporarily discontinued playing hockey and wishes also to return to the clarinet.
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Silva, Paulo Celso. "Cidade. City. Cité. Smartcity. O espaço contemporâneo do Período Técnico Científico Informacional. Duas experiências globais." Revista Observatório 1, no. 1 (September 30, 2015): 233. http://dx.doi.org/10.20873/uft.2447-4266.2015v1n1p233.

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Apresentamos, em linhas gerais, duas experiências urbanas conceitualmente diferentes, seja na maneira de criar e organizar o espaço ou no viver. Celebration uma cidade informacional com um projeto de oferecer ao consumidor-morador uma alternativa estética na união entre a tecnologia e a tradição. Empresas de grande porte oferecem e vendem o que de mais atual pode se esperar em produtos para a casa, modernos aparatos para facilitar a vida. A cidade asiática, por seu turno, oferece o conceito de Smartcity, onde a tecnologia não é oferecida em si-mesmo, mas, conectada à inteligência do morador.Palavras-chave: Geografias da Comunicação; Período Técnico Cientifico Informacional; Cidades Globais; Smartcity; comunicação urbana. ABSTRACTHere, in general, two conceptually different urban experiences, either in the way of creating and organizing the space or live. Celebration an informational city with a project to offer the consumer-dweller an aesthetic alternative to marriage between technology and tradition. Large companies offer and sell what more can be expected in current products for the home, modern devices to make life easier. The Asian city, in turn, offers the concept of Smartcity, where technology is not offered in self, but connected to the resident's intelligence. Keywords: Geographies of communication; Technical Scientific informational Period; Global Cities; Smartcity; Urban Communication. RESUMENEn línea general, presentamos dos experiencias urbanas conceptualmente diferentes, ya sea en la forma de crear y organizar el espacio o vivir. Celebration es una ciudad informacional con un proyecto para ofrecer al consumidor-habitante una alternativa estética en la unión de la tecnología con la tradición. Grandes empresas ofrecen y venden lo más actual se puede esperar de los productos para el hogar, aparatos modernos para hacer la vida más fácil. La ciudad asiática, a su vez, ofrece el concepto de Smartcity, donde la tecnología no se ofrece en si-misma, pero conectado a la inteligencia del residente.Palabras clave: Geografías de la comunicación; Periodo Técnico Científico Informacional; Ciudades Globales; Smartcity; Comunicación Urbana. ReferênciasCASTELLS, Manuel - A sociedade em Rede - A era da informação: Economia, Sociedade e Cultura. São Paulo: Paz e Terra,1999 English version CASTELLS, Manuel. The Information Age: Economy, Society and Culture Vol. I. Cambridge, MA; Oxford, UK: Blackwell.CELEBRATION. Disponível em http://www.celebration.fl.us/town-info/community-profile/ . Acess in 14.10.2013.CELEBRATION COMPANY. The Official Website. 20. May 2005. http://www.celebrationfl.comCELEBRATION HEALTH. Disponível em http://www.celebrationhealth.com. Acesss in 09.10.2013.CELEBRATION NEWS. Disponível em http://www.celebration.fl.us/wp-content/uploads/2013/10/CELEBRATION-NEWS-OCT-2013-low.pdf Acesso em 20.10.2013.CENSUS 2010. Disponível em http://www.census.gov/2010census/ . Acesso em 15.10.2013.DISNEY'S UTOPIA. http://www.123helpme.com/disneys-utopia-view.asp?id=164640. Acesso em 20.10.2013.FREQUENTLY ASKED QUESTIONS, compiled by Kenny Cottrell Acesso em 05.03.2000. O site http://www.home.ptd.net/~glisman/cele2.htm está, atualmente, indisponível.FRANTZ, Douglas & COLLINS, Catherine (2000) Celebration, U.S.A.: living in Disney's brave new town. New York, Henry Holt and Company, 2000.GRUEN ,Victor: The heart of our cities: The urban crisis: diagnosis and cure, Thames and Hudson, London, 1965.HARVEY, David. Condição Pós moderna. São Paulo: Loyola, 1989. English version HARVEY, David. Post modern conditions., Wiley-Blackwell, 1992.MITCHELL, William J. & CASALEGN, Federico. Connected Sustainable Cities. MIT Mobile Experience Lab PublishingOSCEOLA COUNTY PLANNING DEPARTAMENT. Disponível em http://www.osceola.org/. Acesso em 15.10.2013. E-mail Address: oscear@magicnet.net RAINIERI, G. Metrópoles Utópicas, mas possíveis. Entrevista com Jordi Pardo. IN Revista da cultura, Ed. 60 julho de 2012, São Paulo: Livraria Cultura.ROSS, Andrew.: The Celebration Chronicles: Life, Liberty, and The Pursuit of Property Value in Disney's New Town, New York: Ballantine, 1999.SERRES, Michel. A lenda dos Anjos. São Paulo: Aleph, 1995. English version SERRES, Michel. Angels, The modern Myth. Flammarion; First UK edition (October 3, 1995).SONGDOIBD. Disponível em http://www.songdo.com . Acesso em 15.10.2013.STETSON EDUCATION. Disponível em http://www.stetson.edu/celebration. Acesso em 15.10.2013STETSON LIFELONG. Disponível em http://www.stetson.edu/administration/lifelong-learning/media/lifelong-learning-catalog-celebration.pdf . Acesso em 15.10.2013TOWNSEND, Antony M. Smart Cities: Big Data, Civic Hackers, and the Quest for a New Utopia. W. W. Norton & Company; 1 edition, 2013.WILLIAMSON , Lucy. Tomorrow's cities: Just how smart is Songdo? Disponível em http://www.bbc.co.uk/news/technology-23757738 Acesso em 15.10.2013.WILSON, Craig. Mickey Builds a Town: Celebration Puts Disney in Reality's Realm. USA Today. 18. October 1995: 01A, 5B. Também disponível em http://www.sjsu.edu/faculty/wooda/usacelebration.html. Acesso em 15.10.2013.WORKING SONGDO . Disponível em http://www.songdo.com/songdo-international-business-district/the-city/working.aspx. Acessado em: 16.10.2013.YU, J. LIFE AND IDENTITY IN SONGDO. Interview at facebook. Message to paulo.celso@facebook.com, 26/01/2014. Disponível em:Url: http://opendepot.org/2725/ Abrir em (para melhor visualização em dispositivos móveis - Formato Flipbooks):Issuu / Calameo
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Bednekoff, Peter A. "Animal Behavior: An Evolutionary Approach. Edited by Victor S. Lamoureux. Ontario (Canada): Apple Academic Press. $99.95. 320 p.; ill.; index. ISBN: 978-1-926692-78-4. 2011.Animal Behavior: An Evolutionary Approach. Tenth Edition. By John Alcock. Sunderland (Massachusetts): Sinauer Associates. $89.95 (paper). xvii + 522 p.; ill.; index. ISBN: 978-0-87893-966-4. 2013." Quarterly Review of Biology 89, no. 2 (June 2014): 178. http://dx.doi.org/10.1086/676074.

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SCHWARTZ, ARI J., and LAWRENCE R. RICCI. "How Accurately Can Bruises Be Aged in Abused Children? Literature Review and Synthesis." Pediatrics 97, no. 2 (February 1, 1996): 254–57. http://dx.doi.org/10.1542/peds.97.2.254.

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Unlike the severe abuse that was reported in early child abuse literature, more moderate injuries comprise 60% of physical child abuse. These less-severe abuse cases, many with limited, ill-defined bruising, may be more difficult to diagnose than a severe case with multiple-system injury or a child with specific, clearly imprinted bruising. Additionally, as the US Supreme Court observed, "Child abuse is one of the most difficult crimes to detect and prosecute in large part because there often are no witnesses except the victim. Estimates of ages of bruises along with the aging of other injuries such as fractures and brain trauma may offer the only way to associate an injury with a particular perpetrator. Yet, as an aid to child abuse diagnosis and perpetrator identification, visual aging of bruises remains an inexact science, despite recent composite charts that suggest otherwise. Even though it has been stated that it is not possible to age bruises accurately based on color, these opinions have not been represented in the child abuse literature. The study of Langlois and Gresham, to date the only research-based study of bruise aging by appearance, has not yet been cited in the medical literature (Science Citation Index search, August 1994). The available literature does not permit the estimation of a bruise's age with any precision based solely on color. Even for the practitioner to state, as Wilson suggests, that a particular bruise is "consistent with" a specific age implies a level of certainty not supported by the literature. Bruises may be described as "older" if yellow, brown, or green are present, but practitioners should note the limitations of bruise age analysis. Of course, the practitioner must continue to describe the size, shape, location, and color of each bruise accurately. This is best done by written description and drawings along with careful photographic representation. Photographs of a bruise, however, depending on available light and technique, may not represent color accurately. A standard color wheel in the photograph may help. Future research should focus on a number of questions. A study of the aging of bruises, using contusions of known age and history-blinded examiners, could determine how accurate clinical estimates are. Interobserver reliability may also be assessed in such a study. The study of Langlois and Gresham should be repeated to confirm or to refute their findings. A photographic sequence of various bruises from appearance to resolution would give researchers and clinicians a reference of possible colors in different-aged bruises for standardized description. The estimated age of a bruise should never be the sole criteria for a diagnosis of child abuse, but, rather, one component of a comprehensive assessment that incorporates a careful history of the injury, past medical history, family history, associated risk factors, a detailed physical examination, and appropriate laboratory testing.
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Weidow, Brandy L., Jacqueline Vidosh, and John P. Biggerstaff. "The Role of Soluble Fibrin and Fibrin Inhibitory Peptides in Cancer Metastasis." Blood 108, no. 11 (November 16, 2006): 5200. http://dx.doi.org/10.1182/blood.v108.11.5200.5200.

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Abstract Circulating soluble fibrin (sFn) is a marker for ongoing disseminated intravascular coagulation and may have prognostic significance, especially in metastatic cancers. Anti-coagulant therapies have been effective in reducing metastasis in several cancers, but with increased risk of bleeding. The authors have previously demonstrated that soluble fibrin (sFn), which is elevated in many cancer patients, enhances metastasis in an experimental model, and increases platelet/tumor cell adherence by cross-linking platelet aIIbb3 to tumor cell CD54 (a receptor for two of the leukocyte b2 integrins aLb2 and aMb2). sFn also binds to monocyte aMb2 (Mac1), and the peptide sequences of the fibrin(ogen) binding sites for aMb2 and CD54 have recently been identified. It was, therefore, hypothesized that sFn binding to these receptors would result in inhibition of monocyte/tumor cell adherence, and consequently cytotoxicity, which may be reversed by inclusion of blocking peptides. To test this, monocyte adherence to A375 melanoma cells was quantified at physiologically relevant shear rates (35–560 s−1) using a laminar flow perfusion chamber mounted on a Leica DMIRB inverted microscope equipped with a computer controlled digital imaging camera. Effector and target cells were untreated, or incubated with sFn (fibrinogen (Fg), 0.5 mg/ml; fibrin polymerization inhibitor Gly-Pro-Arg-Pro amide (GPRPa), 4 mM; and human thrombin (0.125 U/ml)) in the presence or absence of specific single or combined blocking peptides directed against the sFn binding sites on CD54 (P1) and aMb2 (P2), or the sFn g-chain binding sites for CD54 (P3) and aMb2 (P4). The effect of peptides on thrombin (0.125 U/ml) induced clotting of purified Fg (0.5 mg/ml) was assessed visually. The effect of sFn on monocyte cytotoxicity (effector: target 20:1) against green fluorescent protein (GFP) transfected A375 melanoma cells was measured by GFP release from lysed cells using a Perkin-Elmer Victor-3 96-well fluorescence plate reader. Pre-treatment of tumor cells with sFn significantly (P<0.01) increased monocyte adherence to 68.5 + 0.7% compared to the untreated control (32.9 +1.3%), whereas monocyte pre-treatment had no significant effect (P>0.05) on adherence. However, pre-incubation of both cells with sFn resulted in a significant (P<0.01) inhibition of adherence to 15.95 ± 1.0% (62% inhibition). sFn mediated inhibition of adherence was significantly reduced by pre-treatment of cells with a combination of P1 + P2 (to 22.3 ± 13.8% inhibition; P<0.01), and by pre-incubation of sFn with P3 + P4 (to 9.9 ± 3.6% inhibition; P<0.01). Single peptides blocked to an intermediate level, and controls performed appropriately. Furthermore, blocking peptides did not inhibit thrombin induced clotting of Fg. Pretreatment of both monocytes and A375 cells significantly inhibited specific cytotoxicity by 40% (P < 0.01 compared to untreated cytotoxicity − 28.6 ± 0.7%), and intermediate killing was observed when only one cell type was sFn treated. These results show that sFn incubation with both effector and target cells inhibits both cellular adherence and cytotoxicity by a mechanism involving monocyte aMb2 and tumor cell CD54. Adherence was restored by inclusion of sFn blocking peptides, which did not affect clotting. Clinically, these peptides may be effective therapeutically in reducing sFn mediated immunosuppression and may enhance the immune response to metastasizing cancer cells, without the risk of bleeding problems associated with other therapies.
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Grischuk, Tatiana. "Symptom. Toxic story." Mental Health: Global Challenges Journal 4, no. 2 (October 14, 2020): 19–24. http://dx.doi.org/10.32437/mhgcj.v4i2.91.

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Introduction Such symptoms as hard, complex, bodily or mental feelings, that turn our everyday life into a hell, at first, lead us to a doctor, and then - to a psychotherapist. A sick man is keen to get rid of a symptom. A doctor prescribes medication, that is ought to eliminate a symptom. A psychotherapist searches for a reason of the problem that needs to be removed. There is such an idea that a neurotic symptom, in particular, an anxiety - is a pathological (spare or extra) response of a body. It is generally believed that such anxiety doesn’t have some real, objective reasons and that it is the result of a nervous system disorder, or some disruption of a cognitive sphere etc. Meanwhile, it is known that in the majority of cases, medical examinations of anxious people show that they don’t have any organic damages, including nervous system. It often happens that patients even wish doctors have found at least any pathology and have begun its treatment. And yet - there is no pathology. All examinations indicate a high level of functionality of a body and great performance of the brain's work. Doctors throw their hands up, as they can't cure healthy people. One of my clients told me her story of such medical examinations (which I’ll tell you with her permission). She said that it was more than 10 years ago. So, when she told her doctor all of her symptoms - he seemed very interested in it. He placed a helmet with electrodes on her head and wore some special glasses, when, according to her words, he created some kind of stressful situation for her brain, as she was seeing some flashings of bright pictures in her eyes. She said that he had been bothered with her for quite a long time, and at the end of it he had told her that her brain had been performing the best results in all respects. He noted that he’d rarely got patients with such great health indicators. My client asked the doctor how rare that was. And he answered: “one client in two or three months.” At that moment my client didn’t know whether to be relieved, flattered or sad. But since then, when someone told her that anxiety was a certain sign of mental problems, or problems with the nervous system, or with a body in general, she answered that people who had anxiety usually had already got all the required medical examinations sufficiently, and gave them the advice to go through medical screening by themselves before saying something like that. Therefore, we see a paradoxical situation, when some experts point to a neurotic anxiety as if it is a kind of pathology, in other words - some result of a nervous system disorder. Other specialists in the same situation talk about cognitive impairments. And some, after all the examinations, are ready to send such patients into space Main text I don’t agree with the statement that any neurotic anxiety that happens is excessive and unfounded. It often happens that there is objective, specific and real causes for appearance of anxiety conditions. And these causes require solutions. And it’s not about some organic damages of the brain or nervous system. The precondition that may give a rise to anxiety disorder is the development of such a life story that at some stage becomes too toxic - when, on the one hand, a person interacts with the outside world in a way that destroys his or her personality, and, on the other hand, this person uses repression and accepts such situation as common and normal. Repression - is an essential condition for the development of a neurotic symptom. Sigmund Freud was the first who pointed this out. Repression is such a defense mechanism that helps people separate themselves from some unpleasant feelings of discomfort (pain) while having (external or internal) irritations. It is the situation when, despite the presence of irritations and painful feelings, a person, however, doesn't feel any of it and is not aware of them in his or her conscious mind. Repression creates the situation of so-called emotional anesthesia. As a result, a displacement takes place, so a body starts to signal about the existing toxic life situation via a symptom. Anxiety disorder is usually an appropriate response (symptom) of a healthy body to an unhealthy life situation, which is seen by a person as normal. And it’s common when such a person is surrounded by others (close people), who tend to benefit from such situation, and so they actively maintain this state of affairs, whether it is conscious for them or not. At the beginning of a psychotherapy almost all clients insist that everything is good in their lives, even great, as it is like in everyone else’s life. They say that they have only one problem, which is that goddamn symptom. So they focus all of their attention on that symptom. They are not interested in all the other aspects of their life, and they show their irritation when it comes to talking about it. People want to get rid of it, whatever it takes, but they often tend to keep their lives the way that it was. In such cases a psychotherapist is dealing with the resistance of clients, trying to turn their attention from a symptom to their everyday situation that includes their way of thinking, interactions with themselves and with others and with the external world in order to have the opportunity to see the real problem, to live it through, to rethink and to change the story of their lives. For better understanding about how it works I want to tell you three allegorical tales. The name of the first tale is “A frog in boiling water”. There is one scientific anecdote and an assumption (however, it is noted that such experiments were held in 19 century), that if we put a frog in a pot with warm water and start to slowly heat the water, then this frog get used to the temperature rise and stays in a hot water, the frog doesn’t fight the situation, slowly begins to lose its energy and at the last moment it couldn’t find enough strength and energy to get out of that pot. But if we throw a frog abruptly in hot water - it jumps out very quickly. It is likely that a frog, that is seating in boiling water, will have some responses of the body (symptoms). For example, the temperature of its body will rise, the same as the color of it, etc., that is an absolutely normal body response to the existing situation. But let us keep fantasizing further. Imagine a cartoon where such a frog is the magical cartoon hero, that comes to some magical cartoon doctor, shows its skin, that has changed the color, to the doctor, and asks to change the situation by removing this unpleasant symptom. So the doctor prescribes some medication to return the natural green color of the frog’s skin back. The frog gets back in its hot water. For some period of time this medication helps. But then, after a while, the frog’s body gets over the situation, and the redness of the frog's skin gets back. And the magical cartoon doctor states that the resistance of the body to this medication has increased, and each time prescribes some more and more strong drugs. In this example with the frog it is perfectly clear that the true solution of the problem requires the reduction of the water temperature in that pot. We could propose that magical cartoon frog to think and try to realize that: 1) the water in that pot is hot, and that is the reason why the skin is red; 2) the frog got used to this situation and that is why it is so unnoticeably for this frog; 3) if the temperature of the water in the pot still stay so hot, without any temperature drop, then all the medication works only temporarily; 4) if we lower the temperature in that pot - the redness disappears on its own, automatically and without any medication. Also this cartoon frog, that will go after the doctor to some cartoon physiotherapist, will face the necessity to give itself some answers for such questions as: 1) What is going on? Who has put this frog in that pot? Who is raising the temperature progressively? Who needs it? And what is the purpose or benefit for this person in that? Who benefits? 2) Why did the frog get into the pot? What are the benefits in it for the frog? Or why did the frog agree to that? 3) What does the frog lose when it gets out of this pot? What are the consequences of it for the frog? What does the frog have to face? What are the possible difficulties on the way? Who would be against the changes? With whom the frog may confront? 4) Is the frog ready to take control over its own pot in its own hands and start to regulate the temperature of the water by itself, so to make this temperature comfortable for itself? Is this frog ready to influence by itself on its own living space, to take the responsibility for it to itself? The example “A frog in boiling water” is often used as a metaphorical portrayal of the inability of people to respond (or fight back) to significant changes that slowly happen in their lives. Also this tale shows that a body, while trying to adjust to unfavorable living conditions, will react with a symptom. And it is very important to understand this symptom. Symptom - is the response of a body, it’s a way a body adjusts to some unfriendly environment. Symptom, on the one hand, informs about the existence of a problem, and from the other hand - tries to regulate this problem, at least in some way (like, to remove or reduce), at the level on which it can do it. The process is similar to those when, for example, in a body, while it suffers from some infectious disease, the temperature rises. Thus, on the one hand, the temperature informs about the existence of some infection. On the other hand, the temperature increase creates in a body the situation that is damaging for the infection. So, it would be good to think about in what way does an anxiety symptom help a body that is surrounded by some toxic life situation. And this is a good topic for another article. Here I want to emphasize that all the attempts to remove a symptom without a removal of a problem, without changing the everyday life story, may lead to strengthening of the symptom in the body. Even though the removal of a symptom without elimination of its cause has shown success, it only means that the situation was changed into the condition of asymptomatic existence of a problem. And it is, in its essence, a worse situation. For example, it can cause an occurrence of cancer. The tale “A frog in boiling water” is about the tendency of people to treat a symptom, instead of seeing their real problems, as its cause, and trying to solve it. People don’t want to see their problems, but it doesn’t mean that the problem doesn’t exist. The problem does exist and it continues to destroy a person, unnoticeably for him or her. A person with panic disorder could show us anxiety that is out of control (fear, panic), which, by its essence, seems to exist without any logical reason. Meanwhile the body of such a person could be in such processes that are similar to those that occur in the conditions of some real dangers, when the instinct for self-preservation is triggered and an automatic response of a body to fight or flight implements for its full potential. We can see or feel signs of this response, for example, in cases when some person tries to avoid some real or imaginary danger via attempts to escape (the feeling of fear), or tries to handle the situation by some attempts to fight (the feeling of anger). As I mentioned before, many doctors believe that such fear is pathological, as there is no real reason for such intense anxiety. They may see the cause of the problem in worrisome temper, so they try to remove specifically anxiety rather than help such patients to understand specific reason of their anxiety, they use special psychotherapeutic methods that are designed to help clients to develop logical thinking, so it must help them to realize the groundlessness of their anxiety. In my point of view, such anxiety often has specific, real reasons, when this response of a body, fight or flight, is absolutely appropriate, but not excessive or pathological. Inadequacy, in fact, is in the unconsciousness, but not in the reactions of a body. For a better understanding of the role of anxiety in some toxic environment, that isn’t realized, I want to tell you another allegorical tale called “The wolf and the hare”. Let us imagine that two cages were brought together in one room. The wolf was inside one cage and the hare was in another. The cages were divided by some kind of curtain that makes it impossible for them to see each other. At this point a question arises whether the animals react to each other in some way in such a situation, or not? I think that yes, they will. Since there are a lot of other receptors that participate in the receiving and processing of the sensory information. As well as sight and hearing, we have of course a range of other senses. For example, animals have a strong sense of smell. It is well known that people, along with verbal methods of communicating information, like language and speaking, also have other means of transmitting information - non-verbal, such as tone of voice, intonation, look, gestures, body language, facial expressions etc., that gives us the opportunity to receive additional information from each other. The lie detector works by using this principle: due to detecting non-verbal signals, it distinguishes the level of the accuracy of information that is transmitted. It is assumed, that about 30% of information, that we receive from the environment, comes through words, vision, hearing, touches etc. This is the information that we are aware of in our consciousness, so we could consciously (logically) use it to be guided by. And approximately 70% of everyday information about the reality around us we receive non-verbally, and this information in the majority of cases could remain in us without any recognition. It is the situation when we’ve already known something, and we even have already started to respond to it via our body, but we still don’t know logically and consciously that we know it. We can observe the responses of our own body without understanding what are the reasons for such responses. We can recognize this unconscious information through certain pictures, associations, dreams, or with the help of psychoanalysis. Psychoanalysis is a great tool that can help to recognize the information from the unconscious mind, so that it can be logically processed further on, in other words, a person then receives the opportunity to indicate the real problems and to make right decisions. But let us return to the tale where the hare and the wolf stay in one room and don’t see each other, and, maybe, don’t hear, though - feel. These feelings (in other words - non-verbal information that the hare receives) activate a certain response in the hare’s body. And it reacts properly and adequately to the situation, for instance, the body starts to produce adrenaline and runs the response “fight or flight”. So the hare starts to behave accordingly and we could see the following symptoms: the hare is running around his cage, fussing, having some tremor and an increased heart rate, etc.. And now let us imagine this tale in some cartoon. The hare stays in its house, and the wolf wanders about this house. But the hare doesn’t see the wolf. Though the body of the hare gives some appropriate responses. And then that cartoon hare goes to a cartoon doctor and asks that doctor to give it some pill from its tremor and the increased heart rate. And in general asks to treat in some way this incomprehensible, confusing, totally unreasonable severe anxiety. If we try to replace the situation from this fairy-tale to a life story, we could see that it fits well to the script of interdependent relationships, where there are a couple “a victim and an aggressor”, and where such common for our traditional families’ occurrences as a domestic family violence, psychological and physical abuse take place. Only in 2019 a law was passed that follows the European norms and gives a legislative definition of such concepts as psychological domestic abuse, sexual abuse, physical abuse, bullying, that criminalizes all of these occurrences, establishes the punishment and directly points to people that could be a potential abuser. Among them are: a husband towards his wife, parents towards their children, a wife towards her husband, a superior towards a subordinate, a teacher towards his or her students, children towards each other etc.. When it comes to recognition of something as unacceptable, it seems more easy to put to that category such occurrences as physical and sexual abuse, as we could see here some obvious events. For example, beating or sexual harassment. Our society is ready to respond to these incidents in more or less adequate way, and to recognize them as a crime. But it is harder to deal with the recognition of psychological abuse as an offence. Psychological abuse in our families is common. Psychological abuse occurs through such situations, when one person, while using different psychological manipulations, such as violation of psychological borders, imposition of feeling of guilty or shame, etc., force another person to give up his or her needs and desires, and so in such a way make this person live another’s life. Such actions have an extremely negative effect on the mental health of these people, just as much as physical abuse. It can destroy a person from the inside, ruin self-esteem and a feeling of self-worth, create the situation of absolute dependence such victim from an abuser, including financial dependence etc.. It often happens that psychological abuse takes place against the backdrop of demonstrations of care and love. So you've got this story about the wolf and the hare, that are right next to each other, and the shield between two of them is a repression - a psychological defense mechanism, when a person turns a blind eye to such offences, that take place in his or her own life and towards him or her. And this person considers this as normal, doesn't realize, doesn't have a resource to realize, that it is a crime. Most importantly - doesn’t feel anything, as a repression takes place. But a body responds in a right way - from a certain point of the existence of such a toxic situation the response “fight or flight” is launched in a body at full, in other words - the fear and anxiety with the associated symptoms. The third allegorical tale I called “Defective suit”, which I read in the book of Clarissa Pinkola Estés with the name “Running With the Wolves". “Once one man came to a tailor and started to try on a suit. When he was standing in front of a mirror, he saw that the costume had uneven edges. - Don’t worry, - said the tailor. - If you hold the short edge of the suit by your left hand - nobody notices it. But then the man saw that a lapel of a jacket folded up a little bit. - It's nothing. You only need to turn your head and to nail it by your chin. The customer obeyed, but when he put on trousers, he saw that they were pulling. - All right, so just hold your trousers like this by your right hand - and everything will be fine, - the tailor comforts him. The client agreed with him and took the suit. The next day he put on his new suit and went for a walk, while doing everything exactly in the way that the tailor told him to. He waddled in a park, while holding the lapel by his chin, and holding the short edge of the suit by his left hand, and holding his trousers by his right hand. Two old men, who were playing checkers, left the game and started to watch him. - Oh, God! - said one of them. - Look at that poor cripple. - Oh, yes - the limp - is a disaster. But I'm wondering, where did he get such a nice suit?” Clarissa wrote: “The commentary of the second old man reflects the common response of the society to a woman, who built a great reputation for herself, but turned into a cripple, while trying to save it. “Yes, she is a cripple, but look how great her life is and how lovely she looks.” When the “skin” that we put on ourselves towards society is small, we become cripples, but try to hide it. While fading away, we try to waddle perky, so everyone could see that we are doing really well, everything is great, everything is fine”. As for me, this tale is also about the process of forming a symptom in a situation when one person tries very hard to match to another one, whether it is a husband, a wife or parents. It’s about a situation when such a person always tries to support the other one, while giving up his or her own needs and causing oneself harm in such a way by feeling a tension every day, that becomes an inner normality. And so this person doesn’t give oneself a possibility to relax, to be herself (or himself), to be spontaneous, free. As a result, in this situation the person, who was supported, looks perfect from the outside, but those who tried to match, arises some visible defect, like a limp - a symptom. And so this person lives like a cripple, under everyday stress and tension, trying to handle it, while sacrificing herself (or himself) and trying to maintain this situation, so not to lose the general picture of a beautiful family and to avoid shame. The tailor, who made this defective suit and tells how to wear the suit properly, in order to keep things going as they are going, often is a mother who raised a problematic child and then tells another person how to deal with her child in the right way. It is the situation when a mother-in-law tells her daughter-in-law how to treat her son properly. In other words, how to support him, when to keep silent, to handle, how to fit in, so that her problematic son and this relationship in general looks perfect. Or vice versa, when a mother-in-law tells her son-in-law how to support her problematic daughter, how to fit in etc.. When, for example, a woman acts like this in her marriage and with her husband, with these excessive efforts to fit in - then after a while everybody will talk like: “Look at this lovely man: he lives with his sick wife, and their family seems perfect!”. But when such a woman becomes brave enough to relax and to just let the whole thing go, everybody will see that the relationship in her marriage isn’t perfect, and it is the other one who has problems. Each time when someone tries excessively to match up to another one, while turning oneself in some kind of a cripple, - he or she, on the one hand, supports the comfort of that person, to whom he or she tries to match up, and on the other hand - such a situation always arises in that person such conditions as a continuous tension, anxiety, fear to act spontaneously. A symptom - is like a visible defect, that shows itself through the body (and may look like some kind of injury). It is the result of a hidden inner prison. As a result of evolution, a pain tells us about a problem that is needed to be solved. When we repress our pain we can’t see our needs and our problems at full. And then a body starts to talk to us via a symptom. Psychotherapy aims for providing a movement from a symptom to a resumption of sensitivity to feelings, a resumption of the ability to feel your psychological pain, so you can realize your own toxic story. In this perspective another fairy-tale looks interesting to analyze - it is Andersen's fairytale “Princess and the Pea”. In the tale a prince wanted to find a princess to marry. There was one requirement for women candidates, so the prince could select her among commoner - high level of sensitivity, as the real princess would feel a pea through the mountain of mattresses, and so she could have the ability to feel discomfort, to be in a good contact with her body, to tell about her discomfort without such feeling as shame and guilt, and to refuse that discomfort, so to have the readiness to solve her problems and to demand from others the respect for her needs. It is common for our culture that the expression “a princess on a pea” very often uses for a negative meaning. So people who are in good contact with their body and who can demand comfort for themselves are often called capricious. At the same time the heroes who are ready to suffer and to tolerate their pain, who are able to repress (stop to feel) their pain represents a good example to be followed in our society. So, we may see the next algorithm in cases of various anxiety disorders: the existence of some toxic situation that brings some danger to a person. And we need not to be confused: a danger exists not for a body, but for a personality. A toxic live situation as well as having a panic attack is not a threat for the health of a body (that is what medical examinations show), and vice versa - it’s like every day intensive sport training, that could be good for your health only to some degree. A toxic situation destroys a person as a personality, who longs for one self’s expression; the existence of such a defense mechanism as repression - it’s a life with closed eyes, in pink glasses, when there is inability (or the absence of the desire) to see its own toxic story; 3.the presence of a symptom - a healthy response of a body “fight or flight” to some toxic situation; displacement - it’s replacement of the attention from the situation to a symptom, when a person starts to see and search for the problem in some other place, not where it really is. A symptom takes as some spare, pathological reaction that we need to get rid of. The readiness to fight the symptom arises, and that is the goal of such methods of therapy as pharmacological therapy, CBT and many others; the absence of adequate actions that are directed towards the change of a toxic situation itself. The absence of the readiness to show aggression when it comes to protect its space. All of it is a mechanism of formation of primary anxiety and preparation for launch of secondary anxiety. A complete anxiety disorder is the interaction between a primary and a secondary anxiety.
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Moses, Kelema Lee. "Economies of the City: Honolulu’s Financial Plaza of the Pacific." eTropic: electronic journal of studies in the tropics 17, no. 1 (April 25, 2018). http://dx.doi.org/10.25120/etropic.17.1.2018.3639.

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This paper concerns one monumental architectural structure that defined Honolulu’s business economy and approaches to urban planning in the Central Business District (CBD) during the 1960s – the Financial Plaza of the Pacific. As indicated from its moniker, the design and construction of the edifice highlighted Hawai‘i’s physical location as a global crossroads. The international vision of this “commercial condominium”, and by extension Honolulu, addressed the effects of urban blight and suburban flight that plagued the CBD in the years leading up to, and following, U.S. statehood. The merger of three corporate enterprises (Castle Cooke, Bank of Hawaii, and American Savings and Loan) at the Financial Plaza of the Pacific functioned as means to display corporate reinvestment in the district. The architects of the project, Leo S. Wou Associates and Victor Gruen Associates, desired to create a spatially unified environment with outdoor public space and art projects as loci for human interaction. Ultimately, the Financial Plaza of the Pacific reveals the ways in which Honolulu operated – and continues to operate – as a living city spurred by enterprise and revitalization.
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41

"Mall maker: Victor Gruen, architect of an American dream." Choice Reviews Online 41, no. 10 (June 1, 2004): 41–5707. http://dx.doi.org/10.5860/choice.41-5707.

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42

Scodeller, Dario. "Victor Gruen e lo shopping mall come modello di social design." Storia e Futuro Giugno 2022, no. 55 (September 20, 2022). http://dx.doi.org/10.30682/sef5522d.

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Il saggio ricostruisce la genesi dello shopping mall come modello spaziale per il commercio contemporaneo, illustrandone la sua concezione nel contesto dello sviluppo della città americana del secondo dopoguerra ed esaminando alcuni dei motivi che hanno reso tale modello uno dei luoghi privilegiati della socialità contemporanea. Formulato sul piano teorico e operativo dallo Studio Gruen, il concetto spaziale e sociale del mall si è progressivamente insinuato in molte altre tipologie architettoniche, commerciali e non commerciali, promuovendone principalmente la dimensione ludico-commerciale rispetto all’originale formulazione, che prevedeva una equilibrata integrazione tra retail e servizi in una fruizione pedonalizzata. Il saggio si interroga, infine, sul fenomeno del deadmalling (lo smantellamento e la chiusura dei centri commerciali), che porrà nei prossimi decenni problemi di riconversione di questi luoghi, rendendo forse di nuovo attuale una delle originali vocazioni del mall come centro civico di aggregazione sociale. This essay reconstructs the genesis of the shopping mall as a spatial model for contemporary retail trade, outlining its conception in the context of urban development in the United States after World War II. It also explores some of the reasons that have made this model one of the privileged spaces of contemporary socialization. Studio Gruen is credited with developing the spatial and social concept of the mall from a theoretical and practical point of view; the mall has progressively made its way into many other architectural typologies, both commercial and non-commercial, mainly promoting its recreational-commercial dimension as opposed to the original design, which envisaged a balanced integration of retail and facilities in a pedestrian-oriented context. Finally, the essay examines the phenomenon of “deadmalling” (the dismantling and closure of shopping centres), which will create the issue of having to decide how to reconvert these places in the coming decades, perhaps giving new relevance to one of the original functions of the mall as a social space for aggregation.
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Gregg, Kelly. "Victor Gruen versus Jan Gehl – and the contemporary model of pedestrianization." Journal of Urban Design, November 18, 2022, 1–18. http://dx.doi.org/10.1080/13574809.2022.2147491.

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"Review: Victor Gruen: From Urban Shop to New City, by Alex Wall." Journal of the Society of Architectural Historians 66, no. 3 (September 1, 2007): 411–12. http://dx.doi.org/10.1525/jsah.2007.66.3.411.

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Baldauf, Anette. "Shopping Town USA. Victor Gruen, der Kalte Krieg und die Shopping Mall." L'Homme 17, no. 2 (January 2006). http://dx.doi.org/10.7767/lhomme.2006.17.2.81.

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46

Oberndorfer, Ulrich, and Andreas Ziegler. "2002 German Federal Elections and Associated Energy Policy: How Were Energy Corporations Financially Affected?" Jahrbücher für Nationalökonomie und Statistik 229, no. 5 (January 1, 2009). http://dx.doi.org/10.1515/jbnst-2009-0504.

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SummaryThis paper analyzes the effect of the 2002 German federal elections to the Lower House of Parliament (Bundestag) on the financial performance of German energy corporations.We consider the last minute victory of the government coalition consisting of Social Democrats and the Green party which was generally associated with a major shift in energy policy towards the promotion of renewable energies and a phasing out of nuclear energy. Our event study approach is based on the application of the Fama-French three-factor model to estimate abnormal stock returns. The results of the empirical analysis imply neither for traditional utilities nor for renewable energy corporations any robust positive or negative impact of the elections and therefore of the general energy policy direction of the government in the next legislative period.
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47

Hollo, Ashley, Sara Kohlbeck, Mark Nimmer, and Michael Levas. "Association between Well-being and Community Assets in a Cohort of Youth Victims of Violence in an Urban Setting." HPHR Journal, no. 59 (2021). http://dx.doi.org/10.54111/0001/ggg1.

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Objective The primary purpose of this study is to determine if there is an association between proximity to protective community assets and youth well-being following exposure to violence. Methods This study is a retrospective data analysis using existing data from 471 participants in a violence intervention program. Street addresses of participants were mapped using ArcMap version 10.8.1 mapping software and a buffer analysis was conducted to determine the association between victim well-being and proximity to green space. Results Living close to a green space is associated with decreased fatigue at 1000 ft (p=0.3), 1500 ft (p=0.01), and 2000ft (p=0.008). Proximity to green space is associated with increased overall psychosocial well-being at 1500ft (p=0.004) and 2000ft (p<0.001). Living close to green space was also associated with increased anxiety in youth victims of violence at 1000ft (p=0.027). Conclusions A relationship exists between proximity to green space and youth fatigue and overall well-being following exposure to violence. However, those victims of violence who live closest to green spaces report higher anxiety scores. Subsequent research should focus on determining why proximity to green space differentially impacts youth well-being in the face of violence.
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Masso, Majid. "Accurate and efficient structure-based computational mutagenesis for modeling fluorescence levels of Aequorea victoria green fluorescent protein mutants." Protein Engineering, Design and Selection 33 (2020). http://dx.doi.org/10.1093/protein/gzaa022.

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Abstract A computational mutagenesis technique was used to characterize the structural effects associated with over 46 000 single and multiple amino acid variants of Aequorea victoria green fluorescent protein (GFP), whose functional effects (fluorescence levels) were recently measured by experimental researchers. For each GFP mutant, the approach generated a single score reflecting the overall change in sequence-structure compatibility relative to native GFP, as well as a vector of environmental perturbation (EP) scores characterizing the impact at all GFP residue positions. A significant GFP structure–function relationship (P &lt; 0.0001) was elucidated by comparing the sequence-structure compatibility scores with the functional data. Next, the computed vectors for GFP mutants were used to train predictive models of fluorescence by implementing random forest (RF) classification and tree regression machine learning algorithms. Classification performance reached 0.93 for sensitivity, 0.91 for precision and 0.90 for balanced accuracy, and regression models led to Pearson’s correlation as high as r = 0.83 between experimental and predicted GFP mutant fluorescence. An RF model trained on a subset of over 1000 experimental single residue GFP mutants with measured fluorescence was used for predicting the 3300 remaining unstudied single residue mutants, with results complementing known GFP biochemical and biophysical properties. In addition, models trained on the subset of experimental GFP mutants harboring multiple residue replacements successfully predicted fluorescence of the single residue GFP mutants. The models developed for this study were accurate and efficient, and their predictions outperformed those of several related state-of-the-art methods.
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Boomiraj, K., R. Jagadeeswaran, S. Karthik, R. Poornima, S. Jothimani, and R. Jude Sudhagar. "Assessing the Carbon Sequestration Potential of Coconut Plantation in Vellore District of Tamil Nadu, India." International Journal of Environment and Climate Change, December 31, 2020, 618–24. http://dx.doi.org/10.9734/ijecc/2020/v10i1230345.

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Agriculture, very often falls victim of climate change around the world. Adopting a cost efficient system of agricultural production with minimal environmental impacts, depends on the selection of best cropping system and associated farming practices. The coconut farming and coconut agroecosystem is one of the country’s largest agricultural systems and sectors that could substantially preserve carbon dioxide (CO2) through sequestration. Tamil Nadu state is one of the largest growers of coconut with an area of 443000 ha. In the present investigation the Vellore district was chosen as study area. Coconut data such as tree diameter and tree height were collected from the Tall (Aliyar nagar 1), Dwarf (Chowghat Orange Dwarf (COD)) and Chowghat Green Dwarf (CGD) varieties at different ages (five, fifteen, twenty and twenty-fifth years) at various plantations of Vellore district. The carbon sequestered by five, ten, fifteen, twenty and twenty-five-years old coconut tall variety trees were found to be 1.32, 1.97, 2.11, 3.10 and 3.96 tons per acre per year, respectively. Similarly, five, ten, fifteen, twenty and twenty-five-year-old coconut dwarf variety could able to sequester 1.45, 1.27, 1.58, 2.03 and 2.63 tons per acre per year, respectively in Vellore district. The C sequestration potential of ten year old coconut tree (Tall or Dwarf) were 18 to 28 kg per tree per year approximately. The fifteen years (2003-04 to 2017-18) coconut plantation of both tall and dwarf varieties in Vellore district had sequestered 1.15 million tons of carbon from the atmosphere.
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Holloway, Donell Joy, Lelia Green, and Kylie Stevenson. "Digitods: Toddlers, Touch Screens and Australian Family Life." M/C Journal 18, no. 5 (August 20, 2015). http://dx.doi.org/10.5204/mcj.1024.

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Introduction Children are beginning to use digital technologies at younger and younger ages. The emerging trend of very young children (babies, toddlers and pre-schoolers) using Internet connected devices, especially touch screen tablets and smartphones, has elicited polarising opinions from early childhood experts. At present there is little actual research about the risks or benefits of tablet and smartphone use by very young children. Current usage recommendations, based on research into passive television watching which claims that screen time is detrimental, is in conflict with advice from education experts and app developers who commend interactive screen time as engaging and educational. Guidelines from the health professions typically advise strict time limits on very young children’s screen-time. Based for the most part on policy developed by the American Academy of Paediatrics, it is usually recommended that children under two have no screen time at all (Brown), and children over this age have no more than two hours a day (Strasburger, et al.). On the other hand, early childhood education guidelines promote the development of digital literacy skills (Department of Education). Further, education-based research indicates that access to computers and the Internet in the preschool years is associated with overall educational achievement (Bittman et al.; Cavanaugh et al; Judge et al; Neumann). The US based National Association for Education of Young Children’s position statement on technology for zero to eight year-olds declares that “when used intentionally and appropriately, technology and interactive media are effective tools to support learning and development” (NAEYC). This article discusses the notion of Digitods—a name for those children born since the introduction of the iPhone in 2007 who have ready access to touchscreen technologies since birth. It reports on the limited availability of evidence-based research about these children’s ICT use concluding that current research and recommendations are not grounded in the everyday life of very young children and their families. The article then reports on the beginnings of a research project funded by the Australian Research Council entitled Toddlers and Tablets: exploring the risks and benefits 0-5s face online. This research project recognises that at this stage it is parents who “are the real experts in their toddlers’ use of screen technologies. Accordingly, the project’s methodological approach draws on parents, pre-schoolers and their families as communities of practice in the construction of social meaning around toddlers’ use of touch screen technology. Digitods In 2000 Bill Gates introduced the notion of Generation I to describe the first cohort of children raised with the Internet as a reality in their lives. They are those born after the 1990s and will, in most cases; have no memory of life without the Net. [...] Generation I will be able to conceive of the Internet’s possibilities far more profoundly than we can today. This new generation will become agents of change as the limits of the Internet expand to include educational, scientific, and business applications that we cannot even imagine. (Gates)Digitods, on the other hand, is a term that has been used in education literature (Leathers et al.) to describe those children born after the introduction of the iPhone in 2007. These children often begin their lives with ready access to the Internet via easily usable touch screen devices, which could have been designed with toddlers’ touch and swipe movements in mind. Not only are they the youngest group of children to actively engage with the Internet they are the first group to grow up with a range of mobile Internet devices (Leathers et al.). The difference between Digitods and Gates’s Generation I is that Digitods are the first pre-verbal, non-ambulant infants to have ready access to digital technologies. Somewhere around the age of 10 months to fourteen months a baby learns to point with his or her forefinger. At this stage the child is ready to swipe and tap a touch screen (Leathers et al.). This is in contrast to laptops and PCs given that very young children often need assistance to use a mouse or keyboard. The mobility of touch screen devices allows very young children to play at the kitchen table, in the bedroom or on a car trip. These mobile devices have, of course, a myriad of mobile apps to go with them. These apps create an immediacy of access for infants and pre-schoolers who do not need to open a web browser to find their favourite sites. In the lives of these children it seems that it has always been possible to touch and swipe their way into games, books and creative and communicative experiences (Holloway et al. 149). The interactivity of most pre-school apps, as opposed to more passive screen activities such as watching television shows or videos (both offline or online), requires toddlers and pre-schoolers to pay careful attention, think about things and act purposefully (Leathers et al.). It is this interactivity which is the main point of difference, one which holds the potential to engage and educate our youngest children. It should be noted within this discussion about Digitods that, while the trope Digital Natives tends to homogenise an entire generation, the authors do not assume that all children born today are Digitods by default. Many children do not have the same privileged opportunities as others, or the (parental) cultural capital, to enable access, ease of use and digital skill development. In addition to this it is not implied that Digitods will be more tech savvy than their older siblings. The term is used more to describe and distinguish those children who have digital access almost since birth—in order to differentiate or tease out everyday family practices around these children’s ICT use and the possible risks and benefits this access affords babies, toddlers and pre-schoolers. While the term Digital Native has also been criticised as being a white middle class phenomenon this is not necessarily the case with Digitods. In the Southeast Asia and the Pacific region developed countries like Japan, Korea, New Zealand and Singapore have extremely high rates of touchscreen use by very young children (Child Sciences; Jie; Goh; Unantenne). Other countries such as the Philippines and Indonesia have moved to a high smart phone usage by very young children while at the same time have only nascent ICT access and instruction within their education systems (Unantenne). The Digitod Parent Parents of Digitods are usually experienced Internet users themselves, and many are comfortable with their children using these child-friendly touch screen devices (Findahl). Digital technologies are integral to their everyday lives, often making daily life easier and improving communication with family and friends, even during the high pressure parenting years of raising toddlers and pre-schoolers. Even though many parents and caregivers are enabling very young children’s use of touch screen technologies, they are also concerned about the changes they are making. This is because very young children’s use of touch screen devices “has become another area where they fear possible criticism and in which their parental practices risk negative evaluation by others” (Holloway et al). The tensions between expert advice regarding young children’s screen-time and parents’ and caregivers’ own judgments are also being played out online. Parenting blogs, online magazines and discussion groups are all joining in the debate: On the one hand, parents want their children to swim expertly in the digital stream that they will have to navigate all their lives; on the other hand, they fear that too much digital media, too early, will sink them. Parents end up treating tablets like precision surgical instruments, gadgets that might perform miracles for their child’s IQ and help him win some nifty robotics competition—but only if they are used just so. (Rosin)Thus, with over 80 000 children’s apps marketed as educational in the Apple App Store alone, parents can find it difficult to choose apps that are worth purchasing (Yelland). Nonetheless, recent research regarding Australian children shows that three to five year olds who access touch screen devices will typically have five or more specific apps to choose from (5.23 on average) (Neumann). With little credible evidence or considered debate, parents have been left to make their own choices about the pros and cons of their young children’s access to touch screens. Nonetheless, one immediate benefit that comes to mind is toddlers and pre-schoolers video chatting with dispersed family member—due to increased globalisation, guest worker arrangements, FIFO (fly-in fly-out) workforces and family separation or divorce. Such clear benefits around sociability and youngsters’ connection with significant others make previous screen-related guidelines out of date and no longer contextually relevant. Little Research Attention Family ownership of tablet devices as well as touch screen phones has risen dramatically in the last five years. With very young children being loaned these technologies by mum or dad, and a tendency in Australia to rely on market-orientated research regarding ownership and usage, there is very little knowledge about touch screen usage rates for very young Australian children. UK and US usage figures indicate that over the last few years there has been a five-fold increase in tablet uptake by zero to eight year olds (Ofcom; Rideout). Although large scale, comparative Australian data is not available, previous research regarding older children indicates that Australia is similar to high use countries like some Scandinavian nations and the UK (Green et al.). In addition to this, two small research projects in Australia, with under 160 participant families each, indicate that two thirds of these children (0-5) use touchscreen devices (Neumann; Coenenna et. al.). Beyond usage figures, there is also very limited evidence-based research about very young children’s app use. Interactive technologies available via touch screen technologies have been available domestically for a very short time. Consequently, “valid scientific research has not been completed and replicated due to [the lack of] available time” (Leathers el al. 129) and longitudinal studies which rely on an intervention group (in this case exposure to children’s apps) and a control group (no exposure) are even fewer and more time-consuming. Interestingly, researchers have revisited the issue of passive screen viewing. A recent 2015 review of previous 2007 research, which linked babies watching videos with poor language development, has found that there was statistical and methodological issues with the 2007 study and that there are no strong inferences to be drawn between media exposure and language development (Ferguson and Donellan). Thus, there seems to be no conclusive evidence-based research on which to inform parents and educators about the possible downside or benefits of touch screen use. Nonetheless, early childhood experts have been quick to weigh in on the possible effects of screen usage, some providing restrictive guidelines and recommendations, with others advocating the use of interactive apps for very young children for their educational value. This knowledge-gap disguises what is actually happening in the lives of real Australian families. Due to the lack of local data, as well as worldwide research, it is essential that Australian researchers obtain a comprehensive understanding about actual behaviour around touch screen use in the lives of children aged between zero and five and their families. Beginning Research While research into very young children’s touch screen use is beginning to take place, few results have been published. When researching two to three year olds’ learning from interactive versus non-interactive videos Kirkorian, Choi and Pempek found that “toddlers may learn more from interactive media than from non-interactive video” (Kirkorian et al). This means that the use of interactive apps on touch screen devices may hold a greater potential for learning than passive video or television viewing for children in this age range. Another study considered the degree to which the young children could navigate to and use apps on touch screen devices by observing and analysing YouTube videos of infants and young children using touch screens (Hourcade et al.). It was found that between the ages of 12 months and 17 months the children filmed seemed to begin to “make meaningful use of the tablets [and] more than 90 per cent of children aged two [had] reached this level of ability” (1923). The kind of research mentioned above, usually the preserve of psychologists, paediatricians and some educators, does not, however, ground very young children’s use in their domestic context—in the spaces and with those people with whom most touch screen usage takes place. With funding from the Australian Research Council Australian, Irish and UK researchers are about to adopt a media studies (domestication) approach to comprehensively investigate digital media use in the everyday lives of very young children. This Australian-based research project positions very young children’s touch screen use within the family and will help provide an understanding of the everyday knowledge and strategies that this cohort of technology users (very young children and their parents) have already developed—in the knowledge vacuum left by the swift appropriation and incorporation of these new media technologies into the lives of families with very young children. Whilst using a conventional social constructionist perspective, the project will also adopt a co-creation of knowledge approach. The co-creation of knowledge approach (Fong) has links with the communities of practice literature (Wegner) and recognises that parents, care-givers and the children themselves are the current experts in this field in terms of the everyday uses of these technologies by very young children. Families’ everyday discourse and practices regarding their children’s touch screen use do not necessarily work through obvious power hierarchies (via expert opinions), but rather through a process of meaning making where they shape their own understandings and attitudes through experience and shared talk within their own everyday family communities of practice. This Toddlers and Tablets research is innovative in many ways. It seeks to capture the enthusiasm of young children’s digital interactions and to pioneer new ways of ‘beginnings’ researching with very young children, as well as with their parents. The researchers will work with parents and children in their broad domestic contexts (including in and out-of-home activities, and grandparental and wider-family involvement) to co-create knowledge about young children’s digital technologies and the social contexts in which these technologies are used. Aspects of these interactions, such as interviews and observations of everyday digital interactions will be recorded (audio and video respectively). In addition to this, data collected from media commentary, policy debates, research publications and learned articles from other disciplinary traditions will be interrogated to see if there are correlations, contrasts, trends or synergies between parents’ construction of meaning, public commentary and current research. Critical discourse tools and methods (Chouliaraki and Fairclough) will be used to analyse verbatim transcripts, video, and all written materials. Conclusion Very young children are uniquely dependent upon others for the basic necessities of life and for the tools they need, and will need to develop, to claim their place in the world. Given the ubiquitous role played by digital media in the lives of their parents and other caregivers it would be a distortion of everyday life for children to be excluded from the technologies that are routinely used to connect with other people and with information. In the same way that adults use digital media to renew and strengthen social and emotional bonds across distance, so young children delight in ‘Facetime’ and other technologies that connect them audio-visually with friends and family members who are not physically co-present. Similarly, a very short time spent in the company of toddlers using touch screens is sufficient to demonstrate the sheer delight that these young infants have in developing their sense of agency and autonomy (https://www.youtube.com/watch?v=aXV-yaFmQNk). Media, communications and cultural studies are beginning to claim a space for evidence based policy drawn from everyday activities in real life contexts. Research into the beginnings of digital life, with families who are beginning to find a way to introduce these technologies to the youngest generation, integrating them within social and emotional repertoires, may prove to be the start of new understandings into the communication skills of the preverbal and preliterate young people whose technology preferences will drive future development – with their parents likely trying to keep pace. Acknowledgment This research is supported under Australia Research Council’s Discovery Projects funding scheme (project number DP150104734). References Bittman, Michael, et al. "Digital Natives? New and Old Media and Children's Outcomes." Australian Journal of Education 55.2 (2011): 161-75. Brown, Ari. "Media Use by Children Younger than 2 Years." Pediatrics 128.5 (2011): 1040-45. Burr, Vivien. Social Constructionism. 2nd ed. London: Routledge, 2003. Cavanaugh, Cathy, et al. "The Effects of Distance Education on K–12 Student Outcomes: A Meta-Analysis." Naperville, Ill.: Learning Point Associates, 2004. 5 Mar. 2009 ‹http://www.ncrel.org/tech/distance/index.html›. Child Sciences and Parenting Research Office. Survey of Media Use by Children and Parents (Summary). Tokyo: Benesse Educational Research and Development Institute, 2014. Coenena, Pieter, Erin Howiea, Amity Campbella, and Leon Strakera. Mobile Touch Screen Device Use among Young Australian Children–First Results from a National Survey. Proceedings 19th Triennial Congress of the IEA. 2015. Chouliaraki, Lilie and Norman Fairclough. Discourse in Late Modernity: Rethinking Critical Discourse Analysis. Edinburgh: Edinburgh UP, 1999. Department of Education. "Belonging, Being and Becoming: The Early Years Learning Framework for Australia." Australian Government, 2009. Ferguson, Christopher J., and M. Brent Donnellan. "Is the Association between Children’s Baby Video Viewing and Poor Language Development Robust? A Reanalysis of Zimmerman, Christakis, and Meltzoff (2007)." Developmental Psychology 50.1 (2014): 129. Findahl, Olle. Swedes and the Internet 2013. Stockholm: The Internet Infrastructure Foundation, 2013. Fong, Patrick S.W. "Co-Creation of Knowledge by Multidisciplinary Project Teams." Management of Knowledge in Project Environments. Eds. E. Love, P. Fong, and Z. Irani. Burlington, MA: Elsevier, 2005. 41-56. Gates, Bill. "Enter 'Generation I': The Responsibility to Provide Access for All to the Most Incredible Learning Tool Ever Created." Instructor 109.6 (2000): 98. Goh, Wendy W.L., Susanna Bay, and Vivian Hsueh-Hua Chen. "Young School Children’s Use of Digital Devices and Parental Rules." Telematics and Informatics 32.4 (2015): 787-95. Green, Lelia, et al. "Risks and Safety for Australian Children on the Internet: Full Findings from the AU Kids Online Survey of 9-16 Year Olds and Their Parents." Cultural Science Journal 4.1 (2011): 1-73. Holloway, Donell, Lelia Green, and Carlie Love. "'It's All about the Apps': Parental Mediation of Pre-Schoolers' Digital Lives." Media International Australia 153 (2014): 148-56. Hourcade, Juan Pablo, Sarah Mascher, David Wu, and Luiza Pantoja. Look, My Baby Is Using an iPad! An Analysis of YouTube Videos of Infants and Toddlers Using Tablets. Proceedings of the 33rd Annual ACM Conference on Human Factors in Computing Systems. ACM, 2015. Jie S.H. "ICT Use Statistics of Households and Individuals in Korea." 10th World Telecommunication/ICT Indicators Meeting (WTIM-12). Korea Internet & Security Agency (KISA), 25-7 Sep. 2012.Judge, Sharon, Kathleen Puckett, and Sherry Mee Bell. "Closing the Digital Divide: Update from the Early Childhood Longitudinal Study." The Journal of Educational Research 100.1 (2006): 52-60. Kirkorian, H., K. Choi, and Pempek. "Toddlers' Word Learning from Contingent and Non-Contingent Video on Touchscreens." Child Development (in press). Leathers, Heather, Patti Summers, and Desollar. Toddlers on Technology: A Parents' Guide. Illinois: AuthorHouse, 2013. NAEYC. Technology and Interactive Media as Tools in Early Childhood Programs Serving Children from Birth through Age 8 [Position Statement]. Washington: National Association for the Education of Young Children, the Fred Rogers Center for Early Learning and Children’s Media at Saint Vincent College, 2012. Neumann, Michelle M. "An Examination of Touch Screen Tablets and Emergent Literacy in Australian Pre-School Children." Australian Journal of Education 58.2 (2014): 109-22. Ofcom. Children and Parents: Media Use and Attitudes Report. London, 2013. Rideout, Victoria. Zero to Eight: Children’s Media Use in America 2013. San Francisco: Common Sense Media, 2013. Rosin, Hanna. "The Touch-Screen Generation." The Atlantic, 20 Apr. 2013. Strasburger, Victor C., et al. "Children, Adolescents, and the Media." Pediatrics 132.5 (2013): 958-61. Unantenne, Nalika. Mobile Device Usage among Young Kids: A Southeast Asia Study. Singapore: The Asian Parent and Samsung Kids Time, 2014. Wenger, Etienne. Communities of Practice: Learning, Meaning, and Identity. New York: Cambridge University Press, 1998. Wenger, Etienne. "Communities of Practice and Social Learning Systems." Organization 7.2 (2000): 225-46. Yelland, Nicola. "Which Apps Are Educational and Why? It’s in the Eye of the Beholder." The Conversation 13 July 2015. 16 Aug. 2015 ‹http://theconversation.com/which-apps-are-educational-and-why-its-in-the-eye-of-the-beholder-37968›.
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