Journal articles on the topic 'Gremlin 1'
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Claesson-Welsh, Lena. "Gremlin: vexing VEGF receptor agonist." Blood 116, no. 18 (November 4, 2010): 3386–87. http://dx.doi.org/10.1182/blood-2010-09-299412.
Full textBeck, Sandra, Thomas Simmet, Iris Müller, Florian Lang, and Meinrad Gawaz. "Gremlin-1 C-Terminus Regulates Function of Macrophage Migration Inhibitory Factor (MIF)." Cellular Physiology and Biochemistry 38, no. 2 (2016): 801–8. http://dx.doi.org/10.1159/000443035.
Full textChatterjee, Madhumita, Alexander Behrendt, Martina Schmid, Sandra Beck, Martina Schneider, Andreas Mack, Iris Müller, Tobias Geisler, and Meinrad Gawaz. "Platelets as a novel source of Gremlin-1: Implications for thromboinflammation." Thrombosis and Haemostasis 117, no. 02 (2017): 311–24. http://dx.doi.org/10.1160/th16-08-0665.
Full textRowan, Simon C., Lucie Piouceau, Joanna Cornwell, Lili Li, and Paul McLoughlin. "Gremlin 1 blocks vascular endothelial growth factor signaling in the pulmonary microvascular endothelium." Pulmonary Circulation 10, no. 1 (October 4, 2018): 204589401880720. http://dx.doi.org/10.1177/2045894018807205.
Full textMitola, Stefania, Cosetta Ravelli, Michela Corsini, Alessandra Gianoncelli, Federico Galvagni, Kurt Ballmer-Hofer, Marco Presta, and Elisabetta Grillo. "Production and Biochemical Characterization of Dimeric Recombinant Gremlin-1." International Journal of Molecular Sciences 23, no. 3 (January 21, 2022): 1151. http://dx.doi.org/10.3390/ijms23031151.
Full textElemam, Noha Mousaad, Abdullah Imadeddin Malek, Esraa Elaraby Mahmoud, Waseem El-Huneidi, and Iman M. Talaat. "Insights into the Role of Gremlin-1, a Bone Morphogenic Protein Antagonist, in Cancer Initiation and Progression." Biomedicines 10, no. 2 (January 28, 2022): 301. http://dx.doi.org/10.3390/biomedicines10020301.
Full textZhu, Zhenbiao, Xiaowei Xing, Shisi Huang, and Yuanyuan Tu. "NAT10 Promotes Osteogenic Differentiation of Mesenchymal Stem Cells by Mediating N4-Acetylcytidine Modification of Gremlin 1." Stem Cells International 2021 (April 12, 2021): 1–10. http://dx.doi.org/10.1155/2021/8833527.
Full textAoshima, Yoichiro, Yasunori Enomoto, Shigeki Muto, Shiori Meguro, Hideya Kawasaki, Isao Kosugi, Tomoyuki Fujisawa, et al. "Gremlin-1 for the Differential Diagnosis of Idiopathic Pulmonary Fibrosis Versus Other Interstitial Lung Diseases: A Clinical and Pathophysiological Analysis." Lung 199, no. 3 (March 26, 2021): 289–98. http://dx.doi.org/10.1007/s00408-021-00440-y.
Full textPark, Sin-Aye. "Role of Gremlin-1 in Cancer." Biomedical Science Letters 24, no. 4 (December 31, 2018): 285–91. http://dx.doi.org/10.15616/bsl.2018.24.4.285.
Full textLavoz, Carolina, Jonay Poveda, Laura Marquez-Exposito, Sandra Rayego-Mateos, Raul R. Rodrigues-Diez, Alberto Ortiz, Jesús Egido, Sergio Mezzano, and Marta Ruiz-Ortega. "Gremlin activates the Notch pathway linked to renal inflammation." Clinical Science 132, no. 11 (June 5, 2018): 1097–115. http://dx.doi.org/10.1042/cs20171553.
Full textWellbrock, Jasmin, Jan K. Hennigs, Björn Schulz, Gabi Vohwinkel, Hans Jörg Baumann, Carsten Bokemeyer, Hans Klose, Walter Fiedler, and Nicole Lüneburg. "Circulating Plasma Levels of Bone Morphogenic Protein Antagonist Gremlin-1 Are Increased in Patients with Pulmonary Arterial Hypertension." Blood 120, no. 21 (November 16, 2012): 5189. http://dx.doi.org/10.1182/blood.v120.21.5189.5189.
Full textKišonaitė, Miglė, Xuelu Wang, and Marko Hyvönen. "Structure of Gremlin-1 and analysis of its interaction with BMP-2." Biochemical Journal 473, no. 11 (May 27, 2016): 1593–604. http://dx.doi.org/10.1042/bcj20160254.
Full textKoroglu, Nadiye, Begum Aydogan Mathyk, Esra Nur Tola, Berna Aslan Cetin, Ilkbal Temel Yuksel, Ismail Dag, and Gonca Yetkin Yıldırım. "Gremlin-1 and gremlin-2 levels in polycystic ovary syndrome and their clinical correlations." Gynecological Endocrinology 35, no. 7 (February 4, 2019): 604–7. http://dx.doi.org/10.1080/09513590.2019.1566452.
Full textNilsson, Eric E., Ginger Larsen, and Michael K. Skinner. "Roles of Gremlin 1 and Gremlin 2 in regulating ovarian primordial to primary follicle transition." REPRODUCTION 147, no. 6 (June 2014): 865–74. http://dx.doi.org/10.1530/rep-14-0005.
Full textTejedor-Santamaria, Lucia, Jose Luis Morgado-Pascual, Laura Marquez-Exposito, Beatriz Suarez-Alvarez, Raul R. Rodrigues-Diez, Antonio Tejera-Muñoz, Vanessa Marchant, et al. "Epigenetic Modulation of Gremlin-1/NOTCH Pathway in Experimental Crescentic Immune-Mediated Glomerulonephritis." Pharmaceuticals 15, no. 2 (January 20, 2022): 121. http://dx.doi.org/10.3390/ph15020121.
Full textBaboota, Ritesh K., Aidin Rawshani, Laurianne Bonnet, Xiangyu Li, Hong Yang, Adil Mardinoglu, Tamar Tchkonia, et al. "BMP4 and Gremlin 1 regulate hepatic cell senescence during clinical progression of NAFLD/NASH." Nature Metabolism 4, no. 8 (August 22, 2022): 1007–21. http://dx.doi.org/10.1038/s42255-022-00620-x.
Full textMarchant, Vanessa, Alejandra Droguett, Graciela Valderrama, M. Eugenia Burgos, Daniel Carpio, Bredford Kerr, Marta Ruiz-Ortega, Jesús Egido, and Sergio Mezzano. "Tubular overexpression of Gremlin in transgenic mice aggravates renal damage in diabetic nephropathy." American Journal of Physiology-Renal Physiology 309, no. 6 (September 15, 2015): F559—F568. http://dx.doi.org/10.1152/ajprenal.00023.2015.
Full textShi, Wei, Jingsong Zhao, Kathryn D. Anderson, and David Warburton. "Gremlin negatively modulates BMP-4 induction of embryonic mouse lung branching morphogenesis." American Journal of Physiology-Lung Cellular and Molecular Physiology 280, no. 5 (May 1, 2001): L1030—L1039. http://dx.doi.org/10.1152/ajplung.2001.280.5.l1030.
Full textWellbrock, Jasmin, Sara Sheikhzadeh, Veronika Bonk, Leticia Oliveira-Ferrer, Kristin Klaetschke, Thomas Streichert, Carsten Bokemeyer, Yskert von Kodolitsch, and Walter Fiedler. "Gremlin-1 Is Overexpressed in Endothelial Cells of Patients with Loeys-Dietz Syndrome Due to Dysregulation of TGF-β Signalling,." Blood 118, no. 21 (November 18, 2011): 3269. http://dx.doi.org/10.1182/blood.v118.21.3269.3269.
Full textSarker, Debashis, Udai Banerji, Sarah Patricia Blagden, Natalie Cook, T. R. Jeffry Evans, Elizabeth Ruth Plummer, Marina Braun, et al. "A multi-modular phase I/II study of UCB6114, a first-in-class, fully human IgG4P anti-Gremlin-1 monoclonal antibody, as monotherapy and in combination with mFOLFOX6 or trifluridine/tipiracil, for patients with advanced gastrointestinal (GI) tumors." Journal of Clinical Oncology 40, no. 4_suppl (February 1, 2022): TPS221. http://dx.doi.org/10.1200/jco.2022.40.4_suppl.tps221.
Full textLi, Qian, Yongwei Huo, Yonghong Guo, Xiaoyan Zheng, Wengang Sun, and Zhiming Hao. "Generation and Applications of a DNA Aptamer against Gremlin-1." Molecules 22, no. 5 (April 28, 2017): 706. http://dx.doi.org/10.3390/molecules22050706.
Full textAl-Najeem, Hadeel Thaeir, and Arshad Noori Ghani Al-Dujaili. "Assessment of Gremlin-1 Level in Pulmonary arterial hypertension disease." Research Journal of Pharmacy and Technology 10, no. 11 (2017): 3803. http://dx.doi.org/10.5958/0974-360x.2017.00690.4.
Full textKaragiannis, George S., Natasha Musrap, Punit Saraon, Ann Treacy, David F. Schaeffer, Richard Kirsch, Robert H. Riddell, and Eleftherios P. Diamandis. "Bone morphogenetic protein antagonist gremlin-1 regulates colon cancer progression." Biological Chemistry 396, no. 2 (February 1, 2015): 163–83. http://dx.doi.org/10.1515/hsz-2014-0221.
Full textKoli, Katri, Frank Wempe, Anja Sterner-Kock, Anna Kantola, Martina Komor, Wolf-K. Hofmann, Harald von Melchner, and Jorma Keski-Oja. "Disruption of LTBP-4 function reduces TGF-β activation and enhances BMP-4 signaling in the lung." Journal of Cell Biology 167, no. 1 (October 4, 2004): 123–33. http://dx.doi.org/10.1083/jcb.200403067.
Full textKudryashova, Tatiana, Yuanjun Shen, Andressa Pena, Emily Cronin, Evelyn Okorie, Dmitry Goncharov, and Elena Goncharova. "Inhibitory Antibodies against Activin A and TGF-β Reduce Self-Supported, but Not Soluble Factors-Induced Growth of Human Pulmonary Arterial Vascular Smooth Muscle Cells in Pulmonary Arterial Hypertension." International Journal of Molecular Sciences 19, no. 10 (September 28, 2018): 2957. http://dx.doi.org/10.3390/ijms19102957.
Full textKara, Sevgul, and Metin Karakok. "Investigation of GREMLIN 1, COL15A1 immunoreactivity and the relationship between microvessel density and GREMLIN 1 in papillary renal cell carcinoma and chromophobe renal cell carcinoma." Medical Science and Discovery 3, no. 4 (April 15, 2016): 184. http://dx.doi.org/10.17546/msd.61375.
Full textCostello, Christine M., Katherine Howell, Edwina Cahill, Jean McBryan, Melanie Konigshoff, Oliver Eickelberg, Sean Gaine, Finian Martin, and Paul McLoughlin. "Lung-selective gene responses to alveolar hypoxia: potential role for the bone morphogenetic antagonist gremlin in pulmonary hypertension." American Journal of Physiology-Lung Cellular and Molecular Physiology 295, no. 2 (August 2008): L272—L284. http://dx.doi.org/10.1152/ajplung.00358.2007.
Full textKapoor, Varun N., Sören Müller, Shilpa Keerthivasan, Markus Brown, Cecile Chalouni, Elaine E. Storm, Alessandra Castiglioni, et al. "Gremlin 1+ fibroblastic niche maintains dendritic cell homeostasis in lymphoid tissues." Nature Immunology 22, no. 5 (April 26, 2021): 571–85. http://dx.doi.org/10.1038/s41590-021-00920-6.
Full textKim, Minsoo, Soomin Yoon, Sukmook Lee, Seon Ah Ha, Hyun Kee Kim, Jin Woo Kim, and Junho Chung. "Gremlin-1 Induces BMP-Independent Tumor Cell Proliferation, Migration, and Invasion." PLoS ONE 7, no. 4 (April 13, 2012): e35100. http://dx.doi.org/10.1371/journal.pone.0035100.
Full textYi, Jun, Qunhua Jin, Bin Zhang, Xinqiu Wu, and Dawei Ge. "Gremlin-1 Concentrations Are Correlated with the Severity of Knee Osteoarthritis." Medical Science Monitor 22 (October 29, 2016): 4062–65. http://dx.doi.org/10.12659/msm.897849.
Full textStafford, D. A., L. J. Brunet, M. K. Khokha, A. N. Economides, and R. M. Harland. "Cooperative activity of noggin and gremlin 1 in axial skeleton development." Development 138, no. 5 (February 8, 2011): 1005–14. http://dx.doi.org/10.1242/dev.051938.
Full textLee, E., J. Kim, Y. Bae, S. Park, J. Park, L. Che, and S. Oh. "526 The involvement of gremlin 1 in particulate matter-induced melanogenesis." Journal of Investigative Dermatology 142, no. 12 (December 2022): S271. http://dx.doi.org/10.1016/j.jid.2022.09.541.
Full textO'Reilly, S. "FRI0243 Is The BMP Antagonist Gremlin-1 A Target in Systemic Sclerosis?" Annals of the Rheumatic Diseases 75, Suppl 2 (June 2016): 521.3–521. http://dx.doi.org/10.1136/annrheumdis-2016-eular.3210.
Full textZabkiewicz, C., L. Ye, R. Hargest, and W. Jiang. "Gremlin 1 expression correlates with prognostic features and survival in breast carcinoma." European Journal of Cancer 72 (February 2017): S17—S18. http://dx.doi.org/10.1016/s0959-8049(17)30136-3.
Full textMüller, Iris I., Madhumita Chatterjee, Martina Schneider, Oliver Borst, Peter Seizer, Tanja Schönberger, Sebastian Vogel, et al. "Gremlin-1 inhibits macrophage migration inhibitory factor-dependent monocyte function and survival." International Journal of Cardiology 176, no. 3 (October 2014): 923–29. http://dx.doi.org/10.1016/j.ijcard.2014.08.051.
Full textGraham, Julie R., Cara M. M. Williams, and Zhiyong Yang. "MicroRNA-27b Targets Gremlin 1 to Modulate Fibrotic Responses in Pulmonary Cells." Journal of Cellular Biochemistry 115, no. 9 (July 15, 2014): 1539–48. http://dx.doi.org/10.1002/jcb.24809.
Full textSilvério de Barros, Renata, Grazielle Suhett Dias, Ana Paula do Rosario, Fernanda Vieira Paladino, Gabriel Herculano Lopes, and Alexandre Holthausen Campos. "Gremlin-1 potentiates the dedifferentiation of VSMC in early stages of atherosclerosis." Differentiation 109 (September 2019): 28–33. http://dx.doi.org/10.1016/j.diff.2019.08.001.
Full textRowan, Simon C., Hanne Jahns, Liberty Mthunzi, Lucie Piouceau, Joanna Cornwell, Róisín Doody, Stephen Frohlich, John J. Callanan, and Paul McLoughlin. "Gremlin 1 depletion in vivo causes severe enteropathy and bone marrow failure." Journal of Pathology 251, no. 2 (May 28, 2020): 117–22. http://dx.doi.org/10.1002/path.5450.
Full textGlister, Claire, Leanne Satchell, and Phil G. Knight. "Granulosal and thecal expression of bone morphogenetic protein- and activin-binding protein mRNA transcripts during bovine follicle development and factors modulating their expression in vitro." REPRODUCTION 142, no. 4 (October 2011): 581–91. http://dx.doi.org/10.1530/rep-11-0150.
Full textLeijten, J. C. H., J. Emons, C. Sticht, S. van Gool, E. Decker, A. Uitterlinden, G. Rappold, et al. "Gremlin 1, Frizzled-related protein, and Dkk-1 are key regulators of human articular cartilage homeostasis." Arthritis & Rheumatism 64, no. 10 (September 28, 2012): 3302–12. http://dx.doi.org/10.1002/art.34535.
Full textHu, Kongzu, Heyan Sun, Binjie Gui, and Cong Sui. "Gremlin-1 suppression increases BMP-2-induced osteogenesis of human mesenchymal stem cells." Molecular Medicine Reports 15, no. 4 (February 28, 2017): 2186–94. http://dx.doi.org/10.3892/mmr.2017.6253.
Full textYin, Miao, Mira Tissari, Jenni Tamminen, Irene Ylivinkka, Mikko Rönty, Pernilla von Nandelstadh, Kaisa Lehti, Marko Hyytiäinen, Marjukka Myllärniemi, and Katri Koli. "Gremlin-1 is a key regulator of the invasive cell phenotype in mesothelioma." Oncotarget 8, no. 58 (October 6, 2017): 98280–97. http://dx.doi.org/10.18632/oncotarget.21550.
Full textYin, Miao, Mira Tissari, Jenni Tamminen, Irene Ylivinkka, Mikko Ronty, Kaisa Lehti, Marko Hyytiainen, Marjukka Myllarniemi, and Katri Koli. "OA02.02 Gremlin-1 is a Key Regulator of the Invasive Phenotype in Mesothelioma." Journal of Thoracic Oncology 12, no. 1 (January 2017): S246—S247. http://dx.doi.org/10.1016/j.jtho.2016.11.233.
Full textGooding, Sarah, and Simon J. Leedham. "Gremlin 1 — small protein, big impact: the multiorgan consequences of disrupted BMP antagonism †." Journal of Pathology 251, no. 4 (June 20, 2020): 349–52. http://dx.doi.org/10.1002/path.5479.
Full textLi, Ruohan, Huaixiang Zhou, Mingzhe Li, Qiuyan Mai, Zhang Fu, Youheng Jiang, Changxue Li, et al. "Gremlin-1 Promotes Colorectal Cancer Cell Metastasis by Activating ATF6 and Inhibiting ATF4 Pathways." Cells 11, no. 14 (July 7, 2022): 2136. http://dx.doi.org/10.3390/cells11142136.
Full textSung, Nam Ji, Na Hui Kim, Young-Joon Surh, and Sin-Aye Park. "Gremlin-1 Promotes Metastasis of Breast Cancer Cells by Activating STAT3-MMP13 Signaling Pathway." International Journal of Molecular Sciences 21, no. 23 (December 3, 2020): 9227. http://dx.doi.org/10.3390/ijms21239227.
Full textWellbrock, Jasmin, Lars Harbaum, Hauke Stamm, Jan K. Hennigs, Björn Schulz, Hans Klose, Carsten Bokemeyer, Walter Fiedler, and Nicole Lüneburg. "Intrinsic BMP Antagonist Gremlin-1 as a Novel Circulating Marker in Pulmonary Arterial Hypertension." Lung 193, no. 4 (April 30, 2015): 567–70. http://dx.doi.org/10.1007/s00408-015-9735-5.
Full textWorthley, Daniel L., Michael Churchill, Jocelyn T. Compton, Yagnesh Tailor, Meenakshi Rao, Yiling Si, Daniel Levin, et al. "Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential." Cell 160, no. 1-2 (January 2015): 269–84. http://dx.doi.org/10.1016/j.cell.2014.11.042.
Full textKhatib Shahidi, Roxana, Jenny M. Hoffmann, Shahram Hedjazifar, Laurianne Bonnet, Ritesh K. Baboota, Stephanie Heasman, Christopher Church, et al. "Adult mice are unresponsive to AAV8-Gremlin1 gene therapy targeting the liver." PLOS ONE 16, no. 2 (February 19, 2021): e0247300. http://dx.doi.org/10.1371/journal.pone.0247300.
Full textWorthley, Daniel L., Michael Quante, Samuel Asfaha, Christoph B. Westphalen, Yagnesh H. Tailor, Jean-Philippe Pradere, Juliane S. Troeger, Robert Schwabe, and Timothy C. Wang. "552 The BMP Antagonist Gremlin 1 Labels a Mesenchymal Progenitor Cell in the Gastrointestinal Tract." Gastroenterology 142, no. 5 (May 2012): S—111. http://dx.doi.org/10.1016/s0016-5085(12)60417-x.
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