Dissertations / Theses on the topic 'Graphe simple'
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Islam, Md Kamrul. "Explainable link prediction in large complex graphs - application to drug repurposing." Electronic Thesis or Diss., Université de Lorraine, 2022. http://www.theses.fr/2022LORR0203.
Full textMany real-world complex systems can be well-represented with graphs, where nodes represent objects or entities and links/relations represent interactions between pairs of nodes. Link prediction (LP) is one of the most interesting and long-standing problems in the field of graph mining; it predicts the probability of a link between two unconnected nodes based on available information in the current graph. This thesis studies the LP problem in graphs. It consists of two parts: LP in simple graphs and LP knowledge graphs (KGs). In the first part, the LP problem is defined as predicting the probability of a link between a pair of nodes in a simple graph. In the first study, a few similarity-based and embedding-based LP approaches are evaluated and compared on simple graphs from various domains. he study also criticizes the traditional way of computing the precision metric of similarity-based approaches as the computation faces the difficulty of tuning the threshold for deciding the link existence based on the similarity score. We proposed a new way of computing the precision metric. The results showed the expected superiority of embedding-based approaches. Still, each of the similarity-based approaches is competitive on graphs with specific properties. We could check experimentally that similarity-based approaches are fully explainable but lack generalization due to their heuristic nature, whereas embedding-based approaches are general but not explainable. The second study tries to alleviate the unexplainability limitation of embedding-based approaches by uncovering interesting connections between them and similarity-based approaches to get an idea of what is learned in embedding-based approaches. The third study demonstrates how the similarity-based approaches can be ensembled to design an explainable supervised LP approach. Interestingly, the study shows high LP performance for the supervised approach across various graphs, which is competitive with embedding-based approaches.The second part of the thesis focuses on LP in KGs. A KG is represented as a collection of RDF triples, (head,relation,tail) where the head and the tail are two entities which are connected by a specific relation. The LP problem in a KG is formulated as predicting missing head or tail entities in a triple. LP approaches based on the embeddings of entities and relations of a KG have become very popular in recent years, and generating negative triples is an important task in KG embedding methods. The first study in this part discusses a new method called SNS to generate high-quality negative triples during the training of embedding methods for learning embeddings of KGs. The results we produced show better LP performance when SNS is injected into an embedding approach than when injecting state-of-the-art negative triple sampling methods. The second study in the second part discusses a new neuro-symbolic method of mining rules and an abduction strategy to explain LP by an embedding-based approach utilizing the learned rules. The third study applies the explainable LP to a COVID-19 KG to develop a new drug repurposing approach for COVID-19. The approach learns ”ensemble embeddings” of entities and relations in a COVID-19 centric KG, in order to get a better latent representation of the graph elements. For the first time to our knowledge, molecular docking is then used to evaluate the predictions obtained from drug repurposing using KG embedding. Molecular evaluation and explanatory paths bring reliability to prediction results and constitute new complementary and reusable methods for assessing KG-based drug repurposing. The last study proposes a distributed architecture for learning KG embeddings in distributed and parallel settings. The results of the study that the computational time of embedding methods improves remarkably without affecting LP performance when they are trained in the proposed distributed settings than the traditional centralized settings
Lehbab, Imène. "Problèmes métriques dans les espaces de Grassmann." Electronic Thesis or Diss., Mulhouse, 2023. http://www.theses.fr/2023MULH6508.
Full textThis work contributes to the field of metric geometry of the complex projective plane CP2 and the real Grassmannian manifold of the planes in R6. More specifically, we study all p-tuples, p ≥ 3, of equiangular lines in C3 or equidistant points in CP2, and p-tuples of equi-isoclinic planes in R6. Knowing that 9 is the maximum number of equiangular lines that can be constructed in C3, we develop a method to obtain all p-tuples of equiangular lines for all p ϵ [3,9]. In particular, we construct in C3 five congruence classes of quadruples of equiangular lines, one of which depends on a real parameter ɣ, which we extend to an infinite family of sextuples of equiangular lines depending on the same real parameter ɣ. In addition, we give the angles for which our sextuples extend beyond and up to 9-tuples. We know that there exists a p-tuple, p ≥ 3, of equi-isoclinic planes generating Rr, r ≥ 4, with parameter c, 0< c <1, if and only if there exists a square symmetric matrix, called Seidel matrix, of p × p square blocks of order 2, whose diagonal blocks are all zero and the others are orthogonal matrices in O(2) and whose smallest eigenvalue is equal to - 1/c and has multiplicity 2p-r. In this thesis, we investigate the case r=6 and we also show that we can explicitly determine the spectrum of all Seidel matrices of order 2p, p ≥ 3 whose off-diagonal blocks are in {R0, S0} where R0 and S0 are respectively the zero-angle rotation and the zero-angle symmetry. We thus show an unexpected link between some p-tuples of equi-isoclinic planes in Rr and simple graphs of order p
Montanaro, William M. Jr. "Character Degree Graphs of Almost Simple Groups." Kent State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=kent1398345504.
Full textCRUCIANI, EMILIO. "Simple Randomized Distributed Algorithms for Graph Clustering." Doctoral thesis, Gran Sasso Science Institute, 2019. http://hdl.handle.net/20.500.12571/9951.
Full textYan, Chenyu. "APPROXIMATING DISTANCES IN COMPLICATED GRAPHS BY DISTANCES IN SIMPLE GRAPHS WITH APPLICATIONS." Kent State University / OhioLINK, 2007. http://rave.ohiolink.edu/etdc/view?acc_num=kent1184639623.
Full textKimmel, Jason. "Simple Games on Networks." Oberlin College Honors Theses / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=oberlin1307994412.
Full textOkeke, Nnamdi, and University of Lethbridge Faculty of Arts and Science. "Character generators and graphs for simple lie algebras." Thesis, Lethbridge, Alta. : University of Lethbridge, Faculty of Arts and Science, 2006, 2006. http://hdl.handle.net/10133/532.
Full textvii, 92 leaves ; 29 cm.
Everett, Alistaire Duncan Fraser. "Commuting involution graphs of certain finite simple classical groups." Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/commuting-involution-graphs-of-certain-finite-simple-classical-groups(dd54ee3d-8c94-42cd-87e1-d34770756466).html.
Full textBosi, Gianluca <1991>. "Simple random walks on some partially directed planar graphs." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2019. http://amsdottorato.unibo.it/8914/1/bosi_gianluca_tesi.pdf.
Full textMahfoudh, Mariem. "Adaptation d'ontologies avec les grammaires de graphes typés : évolution et fusion." Thesis, Mulhouse, 2015. http://www.theses.fr/2015MULH1519/document.
Full textOntologies are a formal and explicit knowledge representation. They represent a given domain by their concepts and axioms while creating a consensus between a user community. To satisfy the new requirements of the represented domain, ontologies have to be regularly updated and adapted to maintain their consistency. The adaptation may take different forms (evolution, alignment, merging, etc.), and represents several scientific challenges. One of the most important is to preserve the consistency of the ontology during the changes. To address this issue, we are interested in this thesis to study the ontology changes and we propose a formal framework that can evolve and merge ontologies without affecting their consistency.First we propose TGGOnto (Typed Graph Grammars for Ontologies), a new formalism for the representation of ontologies and their changes using typed graph grammars (TGG). A coupling between ontologies and TGG is defined in order to take advantage of the graph grammars concepts, such as the NAC (Negative Application Conditions), in preserving the adapted ontology consistency. Second, we propose EvOGG (Evolving Ontologies with Graph Grammars), an ontology evolution approach that is based on the TGGOnto formalism that avoids inconsistencies using an a priori approach. We focus on OWL ontologies and we address both : (1) ontology enrichment by studying their structural level and (2) ontology population by studying the changes affecting individuals and their assertions. EvOGG approach defines different types of ontology changes (elementary, composite and complex) and ensures their implementation by the algebraic approach of graph transformation, SPO (Single pushout).Third, we propose GROM (Graph Rewriting for Ontology Merging), an ontologies merging approach that avoids data redundancy and reduces conflict in the merged result. The proposed approach consists of three steps: (1) the similarity search between concepts based on syntactic, structural and semantic techniques; (2) the ontologies merging by the algebraic approach SPO; (3) the global ontology adaptation with graph rewriting rules.To validate our proposals, we have developed several open source tools based on AGG (Attributed Graph Grammar) tool. These tools were applied to a set of ontologies, mainly on those developed in the frame of the CCAlps (Creatives Companies in Alpine Space) European project, which funded this thesis work
Wright, Benjamin. "Graphs associated with the sporadic simple groups Fi₂₄ and BM." Thesis, University of Manchester, 2011. https://www.research.manchester.ac.uk/portal/en/theses/graphs-associated-with-the-sporadic-simple-groups-fi24-and-bm(dcdd493b-929d-4f91-a6bc-48c6b5fda3ba).html.
Full textVirotte-Ducharme, Marguerite-Marie. "Couples fischériens presque simples." Paris 7, 1985. http://www.theses.fr/1985PA077092.
Full textFrondana, Iara Moreira. "Model selection for discrete Markov random fields on graphs." Universidade de São Paulo, 2016. http://www.teses.usp.br/teses/disponiveis/45/45133/tde-02022018-151123/.
Full textNesta tese propomos um critério de máxima verossimilhança penalizada para estimar o grafo de dependência condicional de um campo aleatório Markoviano discreto. Provamos a convergência quase certa do estimador do grafo no caso de um conjunto finito ou infinito enumerável de variáveis. Nosso método requer condições mínimas na distribuição de probabilidade e contrariamente a outras abordagens da literatura, a condição usual de positividade não é necessária. Introduzimos alguns exemplos com um conjunto finito de vértices e estudamos o desempenho do estimador em dados simulados desses exemplos. Também propomos um procedimento empírico baseado no método de validação cruzada para selecionar o melhor valor da constante na definição do estimador, e mostramos a aplicação deste procedimento em dois conjuntos de dados reais.
Matos, Jody Maick Araujo de. "Graph based algorithms to efficiently map VLSI circuits with simple cells." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2018. http://hdl.handle.net/10183/174523.
Full textThis thesis introduces a set of graph-based algorithms for efficiently mapping VLSI circuits using simple cells. The proposed algorithms are concerned to, first, effectively minimize the number of logic elements implementing the synthesized circuit. Then, we focus a significant effort on minimizing the number of inverters in between these logic elements. Finally, this logic representation is mapped into a circuit comprised of only two-input NANDs and NORS, along with the inverters. Two-input XORs and XNORs can also be optionally considered. As we also consider sequential circuits in this work, flip-flops are taken into account as well. Additionally, with high-effort optimization on the number of logic elements, the generated circuits may contain some cells with unfeasible fanout for current technology nodes. In order to fix these occurrences, we propose an area-oriented, level-aware algorithm for fanout limitation. The proposed algorithms were applied over a set of benchmark circuits and the obtained results have shown the usefulness of the method. We show that efficient implementations in terms of inverter count, transistor count, area, power and delay can be generated from circuits with a reduced number of both simple cells and inverters, combined with XOR/XNOR-based optimizations. The proposed buffering algorithm can handle all unfeasible fanout occurrences, while (i) optimizing the number of added inverters; and (ii) assigning cells to the inverter tree based on their level criticality. When comparing with academic and commercial approaches, we are able to simultaneously reduce the average number of inverters, transistors, area, power dissipation and delay up to 48%, 5%, 5%, 5%, and 53%, respectively. As the adoption of a limited set of simple standard cells have been showing benefits for a variety of modern VLSI circuits constraints, such as layout regularity, routability constraints, and/or ultra low power constraints, the proposed methods can be of special interest for these applications. Additionally, some More-than-Moore applications, such as printed electronics designs, can also take benefit from the proposed approach.
Sander, Torsten [Verfasser]. "On simply structured bases of graph eigenspaces / Torsten Sander." [Clausthal-Zellerfeld] : [Univ.-Bibliothek], 2009. http://d-nb.info/997062517/34.
Full textKOUIDER-AISSA, MEKKIA. "Problemes de cycles, chaines et de decomposition de graphes simples." Paris 11, 1991. http://www.theses.fr/1991PA112396.
Full textFallahtoori, Sahar. "Distributed Graph Clustering: Study of DiDiC and Some Simpler Forms." Thesis, KTH, Skolan för informations- och kommunikationsteknik (ICT), 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-174831.
Full textGonzález, Ruiz Jacobo Leonardo 502510, and Ruiz Jacobo Leonardo González. "Calculo del clique-width en graficas simples de acuerdo a su estructura." Tesis de doctorado, Universidad Autónoma del Estado de México, 2018. http://hdl.handle.net/20.500.11799/95286.
Full textCONACyT
Silva, Allan Kardec Messias da. "O degree graph dos grupos alternados e de outros grupos simples." reponame:Repositório Institucional da UnB, 2013. http://repositorio.unb.br/handle/10482/13601.
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O presente trabalho é uma introdução ao estudo de um grafo chamado Degree Graph. Este grafo é associado aos graus dos caracteres de um grupo nito no seguinte modo: os vértices são os primos que dividem os graus dos caracteres irredutíveis e dois vértices p; q são conexos com uma aresta se o grupo possui um caráter irredutível cujo grau é divisível pelo produto pq. O Degree Graph foi estudado inicialmente em grupos solúveis e apenas a pouco teve seus estudos avançados para grupos não solúveis. Donald L. White completou o estudo para grupos simples em 2009 com o artigo `Degree Graphs of Simple Groups', onde ele descreve para todos os grupos nitos simples os correspondentes Degree Graphs. Vamos neste trabalho mostrar estes estudos para todos os grupos alternados, e alguns grupos simples lineares, simpléticos e unitários. O principal resultado que vamos ilustrar em detalhes é o fato que, se n 9, o Degree Graph do grupo alternado An é um grafo completo. Este resultado usa uma conjectura de Alvis, provada por Barry e Ward. _______________________________________________________________________________________ ABSTRACT
The present work is an introduction to the study of a graph called Degree Graph. This graph is associated to the degrees of the characters of a nite group in the following way: the vertices are the primes that divide the degrees of the irreducible characters and two vertices p; q are connected with an edge if the group has an irreducible character whose degree is divisible the product pq. O Degree Graph was initially studied for soluble groups and only recently also for non soluble groups. In 2009 Donald L. White completed the study for simple groups in the paper `Degree Graph of Simple Groups', where he describes for all nite simple groups the corresponding Degree Graphs. In this work, we will illustrate these studies for all alternating groups and some simple linear, symplectic and unitary groups. The main result that we will describe in detail is the fact that if n 9, the Degree Graph of the alternating group An is a complete graph. This result makes use of a conjecture of Alvis, proved by Barry Ward.
Bereczki, Márk. "Graph Neural Networks for Article Recommendation based on Implicit User Feedback and Content." Thesis, KTH, Skolan för elektroteknik och datavetenskap (EECS), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-300092.
Full textRekommendationssystem används ofta på webbplatser och applikationer för att hjälpa användare att hitta relevant innehåll baserad på deras intressen. Med utvecklingen av grafneurala nätverk nådde toppmoderna resultat inom rekommendationssystem och representerade data i form av en graf. De flesta grafbaserade lösningar har dock svårt med beräkningskomplexitet eller att generalisera till nya användare. Därför föreslår vi ett nytt grafbaserat rekommendatorsystem genom att modifiera Simple Graph Convolution. De här tillvägagångssätt är en effektiv grafnodsklassificering och lägga till möjligheten att generalisera till nya användare. Vi bygger vårt föreslagna rekommendatorsystem för att rekommendera artiklarna från Peltarion Knowledge Center. Genom att integrera två datakällor, implicit användaråterkoppling baserad på sidvisningsdata samt innehållet i artiklar, föreslår vi en hybridrekommendatörslösning. Under våra experiment jämför vi vår föreslagna lösning med en matrisfaktoriseringsmetod samt en popularitetsbaserad och en slumpmässig baslinje, analyserar hyperparametrarna i vår modell och undersöker förmågan hos vår lösning att ge rekommendationer till nya användare som inte deltog av träningsdatamängden. Vår modell resulterar i något mindre men liknande Mean Average Precision och Mean Reciprocal Rank poäng till matrisfaktoriseringsmetoden och överträffar de popularitetsbaserade och slumpmässiga baslinjerna. De viktigaste fördelarna med vår modell är beräkningseffektivitet och dess förmåga att ge relevanta rekommendationer till nya användare utan behov av omskolning av modellen, vilket är nyckelfunktioner för verkliga användningsfall.
Kaykobad, M. Tanvir. "Transforming Plane Triangulations by Simultaneous Diagonal Flips." Thesis, Université d'Ottawa / University of Ottawa, 2020. http://hdl.handle.net/10393/40499.
Full textDe, Saedeleer Julie. "The residually weakly primitive and locally two-transitive rank two geometries for the groups PSL(2, q)." Doctoral thesis, Universite Libre de Bruxelles, 2010. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210037.
Full textof rank two on which some group PSL(2,q), q a prime power, acts flag-transitively.
Actually we require that the action be RWPRI (residually weakly primitive) and (2T)1
(doubly transitive on every residue of rank one). In fact our definition of RWPRI requires
the geometry to be firm (each residue of rank one has at least two elements) and RC
(residually connected).
The main goal is achieved in this thesis.
It is stated in our "Main Theorem". The proof of this theorem requires more than 60pages.
Quite surprisingly, our proof in the direction of the main goal uses essentially the classification
of all subgroups of PSL(2,q), a famous result provided in Dickson’s book "Linear groups: With an exposition of the Galois field theory", section 260, in which the group is called Linear Fractional Group LF(n, pn).
Our proof requires to work with all ordered pairs of subgroups up to conjugacy.
The restrictions such as RWPRI and (2T)1 allow for a complete analysis.
The geometries obtained in our "Main Theorem" are bipartite graphs; and also locally 2-arc-transitive
graphs in the sense of Giudici, Li and Cheryl Praeger. These graphs are interesting in their own right because of
the numerous connections they have with other fields of mathematics.
Doctorat en Sciences
info:eu-repo/semantics/nonPublished
Lapalut, Stéphane. "Sémantique formelle et spécifications algébriques du raisonnement sur les graphes conceptuels simples et étendus." Nice, 1997. http://www.theses.fr/1997NICE5148.
Full textSchuhmacher, Michael Verfasser], and Simone Paolo [Akademischer Betreuer] [Ponzetto. "Knowledge Graph Exploration for Natural Language Understanding in Web Information Retrieval / Michael Schuhmacher ; Betreuer: Simone Paolo Ponzetto." Mannheim : Universitätsbibliothek Mannheim, 2016. http://d-nb.info/1120302587/34.
Full textSchuhmacher, Michael [Verfasser], and Simone Paolo [Akademischer Betreuer] Ponzetto. "Knowledge Graph Exploration for Natural Language Understanding in Web Information Retrieval / Michael Schuhmacher ; Betreuer: Simone Paolo Ponzetto." Mannheim : Universitätsbibliothek Mannheim, 2016. http://d-nb.info/1120302587/34.
Full textHérault, Laurent. "Réseaux de neurones récursifs pour l'optimisation combinatoire : application à la théorie des graphes et à la vision par ordinateur." Grenoble INPG, 1991. http://www.theses.fr/1991INPG0019.
Full textPrado, Gerônimo Rodrigues. "Superfosfato simples contendo fosfato de ferro de baixa solubilidade aplicado em solos de várzea do Rio Grande do Sul." Universidade Federal de Santa Maria, 2009. http://repositorio.ufsm.br/handle/1/5499.
Full textSome rocks used in fertilizer production contain impurities of low solubility in water such as iron aluminum phosphate (Fe- Al- P). The use of these rocks generates simple superphosphate which may contain impurity levels that do not meet the fertilizer legislation in Brazil. One of the possibilities for the use of fertilizers containing high degree of impurities of iron phosphate would be to apply in flooded soils. Thus, the aims of this work were: a) to study the phosphorous behavior originating from the simple superphosphate containing impurities of iron phosphate with low solubility in water, when submitted to flooding conditions in different flooding soils from RS used for the cultivation of the rice; b) to study the efficiency of the use of phosphorus originating from fertilizers containing impurities of insoluble iron phosphates in water when compared to single superphosphates without residues of iron phosphates in rice plants (Oryza sativa). Six lowland soils were collected from different places in the State of Rio Grande do Sul: two soils in Santa Maria (Planossolo and Gleissolo) and the others in Santa Vitória do Palmar (Chernossolo); Uruguaiana (Chernossolo); Cachoeirinha (Gleissolo) and Pelotas (Planossolo). The soils were conditioned in 8 L plastic vases. The treatments were structured in a bifatorial 6x3 (six soils, two P sources, simple superphosphate and simple superpohosphate with (Fe-P) residues without P addition). In treatments with P, 100 mg P Kg-1 was added to the soil. A water layer was maintained at 5 cm of height in vases above the soil and the collection of the soil solution was carried out weekly. pH and redox potential were measured immediately after each collection of the solution and the reading of the amount of P, iron and manganese was done just after that. Forty five days after flooding, eight exemplars of rice cultivar IRGA 422 CL were transplanted to be cultivated for 45 more days. The yield of dry matter from aerial part, the P amount in the tissue and the calculation of the P amount absorbed were determined. The results showed an increase of pH and of the amount of P, iron and manganese as well as a decrease of Eh in all soils. The simple superphophate containing insoluble impurities of iron phosphate in water presented behavior similar to simple superphosphate without impurities when applied in soils of meadow from Rio Grande do Sul, evidencing its potential to be used in these soils Rio Grande do Sul, evidencing its potential to be used in these soils.
Algumas rochas utilizadas na produção de fertilizantes contêm impurezas de baixa solubilidade em água, destacando-se alguns fosfatos de ferro-alumínio (Fe-Al-P). A utilização destas rochas pode gerar superfosfato simples contendo essas impurezas o que não atende a legislação de fertilizantes no Brasil. Uma das possibilidades para o aproveitamento dos fertilizantes com grau elevado de impurezas de fosfato de ferro seria aplicá-los em solos alagados. Portanto, os objetivos do presente trabalho foram: a) estudar o comportamento do fósforo oriundo do superfosfato simples contendo impurezas de fosfatos de ferro com baixa solubilidade em água, quando submetidos a condições de alagamento em diferentes solos de várzea do RS usados para o cultivo do arroz; e b) estudar a eficiência da utilização do fósforo oriundo dos fertilizantes contendo impurezas de fosfatos de ferro insolúveis em água quando comparados a superfosfatos simples sem resíduos de fosfatos de ferro em plantas de arroz (Oryza sativa). Foram coletados seis solos de várzea, de diferentes locais do Estado do Rio Grande do Sul (RS), sendo dois solos na cidade de Santa Maria (Planossolo e Gleissolo) e um solo em cada uma das cidades de Santa Vitória do Palmar (Chernossolo); Uruguaiana (Chernossolo); Cachoeirinha (Gleissolo) e Pelotas (Planossolo). Os solos foram acondicionados em vasos plásticos de 8 L. Os tratamentos foram estruturados em um bifatorial 6x3 (seis solos, duas fontes de fósforo - superfosfato simples e superfosfato simples com resíduos de ferro - e testemunha sem P). Nos tratamentos com fósforo foi adicionado ao solo 100 mg de P kg-1 de solo. Uma lâmina de água foi mantida a 5 cm de altura nos vasos acima do solo e realizou-se a coleta da solução do solo, semanalmente. O pH e o potencial redox foram medidos imediatamente após cada coleta da solução e em laboratório se procedeu a determinação dos teores de fósforo, ferro e manganês. Transcorrido 45 dias de alagamento, foram transplantadas oito plântulas de arroz cultivar IRGA 422 CL para serem cultivadas por um período de mais 45 dias. Foi determinado a produção de matéria seca da parte aérea (MSPA), o teor de fósforo (P) no tecido e o cálculo da quantidade de P absorvido. Os resultados mostraram aumento no pH, redução do Eh e aumento dos teores de fósforo, ferro e manganês em todos os solos. O superfofasto simples contendo impurezas de fosfato de ferro insolúveis em água apresentou comportamento semelhante ao superfosfato simples sem impurezas quando aplicados nos solos de várzea do Rio Grande do Sul, evidenciando seu potencial para uso nestes solos.
Shdeed, Edouard. "Contribution a l'etude des grandes deflexions elastoplastiques de structures simples soumises aux grandes impulsions de choc de grande energie." Nantes, 1987. http://www.theses.fr/1987NANT2014.
Full textMattos, Bruno Donadelli Trajano. "Cálculo de áreas sem o uso do Teorema Fundamental do Cálculo." Universidade de São Paulo, 2017. http://www.teses.usp.br/teses/disponiveis/55/55136/tde-02022018-090342/.
Full textWe developed a natural strategy, achievable by high school students, for the computation of area of limited regions of the cartesian plane, without making use of more advanced resources of Differential and Integral Calculus.
Shdeed, Edouard. "Contribution à l'étude des grandes délexions élasto-plastiques de structures simples soumises à des impulsions de choc de grande énergie." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb37609935p.
Full textBiswas, Arindam. "Théorie des groupes approximatifs et ses applications." Thesis, Université Paris-Saclay (ComUE), 2016. http://www.theses.fr/2016SACLS573.
Full textIn the first part of this thesis, we study the structure of approximate subgroups inside metabelian groups (solvable groups of derived length 2) and show that if A is such a K-approximate subgroup, then it is K^(O(r)) controlled (in the sense of Tao) by a nilpotent group where r denotes the rank of G=Fit(G) and Fit(G) is the fitting subgroup of G.The second part is devoted to the study of growth of sets inside GLn(Fq) , where we show a bound on the diameter (with respect to any set of generators) for all finite simple subgroups of this group. What we have is - if G is a finite simple group of Lie type with rank n, and its base field has bounded size, then the diameter of the Cayley graph C(G; S) would be bounded by exp(O(n(logn)^3)). If the size of the base field Fq is not bounded then our method gives a bound of q^(O(n(log nq)3)) for the diameter.In the third part we are interested in the growth of sets inside commutative Moufang loops which are commutative loops respecting the moufang identities but without (necessarily)being associative. For them we show that if the sizes of the associator sets are bounded then the growth of approximate substructures inside these loops is similar to those in ordinary groups. In this way for the subclass of finitely generated commutative moufang loops we have a classification theorem of its approximate subloops
Lissner, Simone [Verfasser], and Lutz [Akademischer Betreuer] Graeve. "Intrazelluläres Trafficking des intestinalen Anionenaustauschers Down-Regulated in Adenoma (DRA;SLC26A3) / Simone Lissner. Betreuer: Lutz Graeve." Hohenheim : Kommunikations-, Informations- und Medienzentrum der Universität Hohenheim, 2012. http://d-nb.info/1027353363/34.
Full textLuiz, Simone Weide. "ESTUDO COMPARATIVO DA AQUISIÇÃO DO /R/ NA POSIÇÃO DE ONSET SIMPLES POR CRIANÇAS DE DOIS MUNICÍPIOS DO RIO GRANDE DO SUL." Universidade Federal de Santa Maria, 2012. http://repositorio.ufsm.br/handle/1/6513.
Full textO objetivo geral deste estudo é determinar e comparar a aquisição e o surgimento do rforte em onset simples, bem como a influência das variáveis linguísticas e extralinguísticas na aquisição deste fonema por crianças residentes nos municípios de Santa Maria-RS e Crissiumal-RS. A amostra de fala utilizada na pesquisa é composta por 76 entrevistas em Crissiumal e 60 entrevistas em Santa Maria, com um total de 136 informantes. Os sujeitos possuem idades entre 1:6 e 4:2. Os dados de fala de Santa Maria são provenientes de um banco de dados que contém amostras de fala de crianças com desenvolvimento fonológico típico, o qual foi criado a partir da realização de um projeto de pesquisa. Para a coleta de dados em Crissiumal, foi solicitado que as crianças observassem desenhos temáticos, parte da Avaliação Fonológica da Criança (AFC) (YAVAS, HERNANDORENA & LAMPRECHT, 1991) e também que nomeassem as figuras para observar a forma como elas produzem o r-forte . Os dados foram analisados por faixa etária para se chegar a um perfil aquisitivo. Após, para as análises estatísticas em relação às variáveis linguísticas contexto precedente, contexto seguinte, tonicidade, número de sílabas e posição na palavra; e das variáveis extralinguísticas sexo e idade, contou-se com o apoio do Pacote Computacional VARBRUL, que é um pacote estatístico amplamente utilizado em análises quantitativas variacionistas e de aquisição fonológica. Através da análise dos dados, constatou-se que o /R/ surge aos 2:0 nas crianças residentes em Santa Maria e aos 2:2 nas crianças residentes em Crissiumal. Em Santa Maria, o fonema é considerado adquirido aos 3:6 em onset inicial e aos 3:4 em onset medial. Já em Crissiumal o fonema se estabiliza em onset inicial aos 4:2 e em onset medial aos 4:0. Além disso, em Santa Maria o programa estatístico selecionou as variáveis linguísticas contexto seguinte e número de sílabas em onset inicial e a variável extralinguística sexo, tanto em onset inicial quanto em onset medial. Em Crissiumal, a variável linguística tonicidade foi selecionada em onset inicial e a variável linguística contexto seguinte foi selecionada em onset medial. Concluindo, a partir dos dados coletados, é possível constatar que as crianças residentes em Santa Maria adquirem o /R/ mais cedo que em Crissiumal. Outro aspecto relevante é que a maioria das variáveis linguísticas e as variáveis extralinguísticas consideradas afetam a aquisição do /R/ de forma distinta, conforme a variante dialetal utilizada.
Voivret, Charles. "Texture et comportement des matériaux granulaires à grande polydispersité." Phd thesis, Montpellier 2, 2008. http://www.theses.fr/2008MON20111.
Full textThis work is devoted to the numerical modeling of highly polydisperse granular materials in view of investigating the texture and mechanical behavior in quasi-static shearing. The polydispersity is modeled in terms of size span and curvature of the particle size distributions. A method is proposed to generate representative size distributions both in number and volume of size classes, and the accessible polydispersity parameters are determined for tractable number of particles. A geometrical method is used to construct large samples and to study the resulting texture in a systematic manner as a function of size distribution. These samples are then subjected to simple shear with periodic boundary conditions by means of the contact dynamics method. We show that: 1) The highest level of solid fraction corresponds to uniform distribution by particle volume fractions; 2) The shear strength in the steady state is independent of polydispersity; 3) A detailed analysis of the texture and force transmission indicates that this property results from the mutual compensation between the anisotropies of contact orientations and branch-vector lengths, and also from the fact that the strong force chains are mainly captured by the largest particles; 4) In the presence of adhesion between particles, the Coulomb cohesion increases with size span
Voivret, Charles. "Texture et comportement des matériaux granulaires à grande polydispersité." Phd thesis, Université Montpellier II - Sciences et Techniques du Languedoc, 2008. http://tel.archives-ouvertes.fr/tel-00372125.
Full textSoames, Kieron, and Jonas Lind. "Detecting Cycles in GraphQL Schemas." Thesis, Linköpings universitet, Institutionen för datavetenskap, 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-156174.
Full textXu, Yongchao. "Tree-based shape spaces : definition and applications in image processing and computer vision." Phd thesis, Université Paris-Est, 2013. http://tel.archives-ouvertes.fr/tel-00981623.
Full textLe, Boudec Adrien. "Géométrie des groupes localement compacts. Arbres. Action !" Thesis, Paris 11, 2015. http://www.theses.fr/2015PA112036.
Full textIn Chapter 1 we investigate the class of locally compact lacunary hyperbolic groups. We characterize locally compact groups having one asymptotic cone that is a real tree and whose natural isometric action is focal. We also study the structure of lacunary hyperbolic groups, and prove that in the unimodular case subgroups cannot satisfy a law. We apply the previous results in Chapter 2 to solve the problem of the existence of cut-points in asymptotic cones for connected Lie groups. In Chapter 3 we prove that Neretin's group is compactly presented and give an upper bound on its Dehn function. We also study metric properties of Neretin's group, and prove that some remarkable subgroups are quasi-isometrically embedded. In Chapter 4 we study a family of groups acting on a tree, and whose local action is prescribed by some permutation group. We prove among other things that these groups have property (PW), and exhibit some simple groups in this family. In Chapter 5 we introduce the relation range of a finitely generated group, which is the set of lengths of relations that are not generated by relations of smaller length. We establish a link between simple connectedness of asymptotic cones and the relation range of the group, and give a large class of groups having a relation range as large as possible
Barcellos, Junior Antonio Soares de. "Análise evolutiva da indústria de frigoríficos de produtos suínos no Rio Grande do Sul do ano de 1950 até o ano de 2004: declínio ou simples concentração de mercado?" Universidade do Vale do Rio do Sinos, 2006. http://www.repositorio.jesuita.org.br/handle/UNISINOS/2694.
Full textNenhuma
O objetivo global deste estudo é proceder à verificação da evolução do Setor de Frigoríficos de Produtos Suínos Gaúchos desde o ano de 1950 até o ano de 2004. Neste sentido, a partir do Modelo das 5 Forças de Porter, serão analisados os fatos ocorridos com este Setor Industrial, buscando compreender as razões que fizeram com que o número de empresas concorrentes tenha sofrido uma diminuição tão significativa no período de pouco mais de 50 anos, bem como, a busca do entendimento das possíveis razões de sucesso daquelas que permaneceram no mercado, e se encontram atualmente competindo e disputando acirradamente na busca de um melhor “market share”. Acredita-se que a estratégia adotada e a correta utilização dos recursos, combinados com variáveis externas, muitas vezes de difícil controle, provavelmente possam ser ingredientes importantes para a busca de uma resposta. O aprofundamento destas análises e seus desdobramentos, portanto, se constituem como o eixo central desta pesquisa
This study global objective is to procede the evolution check of Pig Products Freezer Sector from Rio Grande do Sul since 1950 to 2004. In this way, according to the Model of Porter’s 5 Powers, it will be analyzed the occurred facts with this Industrial Sector, looking for understanding not only the reasons which had made the number of contestant companies suffered a significant decreasing in the period around 50 years, but also, the possible success reasons from which continue in the market and find each other, nowadays, competing intensively on the search of a better market share.It is believe that the adopted strategy and the correct resources utilization, combined with external variables, many times with difficult control, probably can be important ingredients for the search of an answer. To make our knowledge deeper about this analysis and its branches, therefore, they constitute themselves as the central axis of this research
Gueydan, Frédéric. "La transition fragile-ductile de la croûte continentale en extension : du terrain à la modélisation." Paris 6, 2001. http://www.theses.fr/2001PA066514.
Full textGramfort, Alexandre. "Localisation et suivi d'activité fonctionnelle cérébrale en électro et magnétoencéphalographie: Méthodes et applications au système visuel humain." Phd thesis, Ecole nationale supérieure des telecommunications - ENST, 2009. http://tel.archives-ouvertes.fr/tel-00426852.
Full textSantos, Adriana Goulart dos. "Estudo do comportamento resiliente de três solos da região de Campo Grande-MS e de relações entre o módulo de resiliência e resultados de ensaios de compressão simples." Universidade de São Paulo, 2003. http://www.teses.usp.br/teses/disponiveis/18/18137/tde-06102009-093939/.
Full textThe resilient modulus knowledge (MR) is fundamental for pavement design, once it is necessary for stresses, strains and deflections calculus in its layers and subgrade, as well as, the analysis of system performance. Although field tests may be used to determine the dynamic behavior of soils, most of researchers favor laboratory tests, based on the fact that such tests are less constrained because of their carefully controlled conditions. Because laboratory procedures are considered complex and highly expensive, it is desirable to establish relationships among MR and other index properties that are relatively simple and usual in pavement construction. In this research, cyclic triaxial tests were performed to determine MR of three soils used in Campo Grande-MS roads. The performance of the models most commonly adopted to represent resilient modulus as a function of state of stress were verified. A mathematical expression among MR, obtained from the cyclic triaxial tests, and the initial tangent modulus, obtained from unconfined compression strength tests, were developed considering different states of stress. Finally, were analyzed the existence of relationships among soils studied in this research, and soils used in previous studies developed at EESC-USP. Results show that this type of empirical correlation presents a satisfactory results, however incisive conclusions cannot be taken without a large number and variety of soils.
Silva, Rubens Elias da. "Guiados por mares e peixes: Memória social, inovação tecnológica e o processo de fragmentação na pequena pesca comercial simples em duas comunidades pesqueiras no Rio Grande do Norte." Universidade Federal da Paraíba, 2012. http://tede.biblioteca.ufpb.br:8080/handle/tede/7281.
Full textCoordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES
This work aims to understand the impact of new technologies incorporated in fishery production in Barra do Cunhaú and Baía Formosa in the northeastern Brazilian state of Rio Grande do Norte, from the standpoint of fishermen and members of their communities regarding the impact of social changes in the current context of modernization. In this study, I attempt to analyze "the way of life" through the qualitative method supported by ethnography, with reference to the social memory of the fishermen and their communities as well as their daily social practices in light of the social changes which have occured within the area of fishery production, and how these engender tensions and conflicts in relation to production and daily practices. These tensions can be attributed to urban restructuring due to the growth of tourism in the region and the incorporation of new technologies in the daily life of these coastal communities. From this standpoint, the transformation of the way of life peculiar to those in a process of modernization, affected the legitimacy of the social construct of honor connected with fishing. What stands out is the fragmentation of the fishing craft as a job, and as a result, the development of the current situation of social vulnerability caused by precarious working conditions which are in opposition to the development of the work technique whose interest is the pursuit of profit - economic rationality, a characteristic of modern urban industrial societies.
Este trabalho objetiva compreender o impacto das novas tecnologias inseridas no âmbito da produção pesqueira em Barra do Cunhaú e Baía Formosa, no Rio Grande do Norte, a partir dos relatos de pescadores e comunitários a respeito das transformações sociais ocorridas mediante tal impacto no atual contexto de modernidade. Neste estudo, busco analisar o modo de vida através do método qualitativo amparado pela etnografia, tendo como referência a memória social dos pescadores e comunitários e as práticas sociais cotidianas no presente face às transformações sociais ocorridas no espaço da produção da pesca, e como estas engendram tensões e conflitos, tanto nas relações de produção quanto nas práticas cotidianas. Essas tensões podem ser atribuídas à reestruturação urbana decorrente do crescimento turístico na região e na inserção das novas tecnologias no cotidiano dessas comunidades costeiras. A partir disso, a transformação do modo de vida peculiar àquelas num processo de estilização do cotidiano, afetou a legitimidade do construto social da honra ligada à pesca. Acentua-se, como conseqüência dessas transformações, a fragmentação do trabalho artesanal da pesca e, em virtude disso, o desenvolvimento do estágio atual de vulnerabilidade social causado pelas precárias condições de trabalho que se contrapõem a um desenvolvimento da técnica de trabalho cujo interesse é a busca do lucro racionalidade econômica característica das sociedades modernas urbanas industriais.
Pereira, Valeska Santana de Sena. "Preval?ncia da infec??o por papilomav?rus humano, herpes simplex tipo 1 e 2 e Chlamydia trachomatis em um segmento da popula??o feminina da grande Natal/RN." Universidade Federal do Rio Grande do Norte, 2011. http://repositorio.ufrn.br:8080/jspui/handle/123456789/13067.
Full textSexually transmitted diseases (STDs) are among the largest public health problems, especially in developing countries. The acquisition of these infections during early sexual activity is common and many infections have a benign course. However, in some pathogens remain in the state of latency can be reactivated and cause productive infection that may progress to severe forms. In addition, some of them are transmitted vertically resulting in congenital infection, causing immediate damage or long-term child. The classic risk factors for sexually transmitted agents are: early onset of sexual and reproductive health, multiple sexual partners throughout life, use of oral contraceptives and co-infections with different pathogens. We present the results of a cross-sectional study aimed to estimate the prevalence of genital infection by human papillomavirus (HPV), Herpes simplex virus (HSV) and Chlamydia trachomatis (CT) in a segment of the female population of the metropolitan area Christmas, among those who enrolled voluntarily sought, Basic Health Units for the examination of cancer screening cervix in the period 2008 to 2010. All participants, a total of 261 women answered a standard questionnaire by which identified the socio-demographic characteristics, classical risk factors for STDs, reproductive and sexual activity and smoking. Of each patient were obtained two samples, one for the completion of the Pap test for detection of cellular changes and the other processed for DNA extraction and analyzed by PCR (polymerase chain reaction) to detect the three pathogens studied. The population of the study was composed of sexually active women aged between 13 and 79 years, mean 38.7 years, most of them being married, low education levels and low incomes. The majority (87%) had normal results on cytology and only 2.7% had low-grade cytological abnormalities. Prevalence rates were 37.9% for HPV, 4.6% for CT and 26% for HSV. HPV prevalence was higher in women under 25, unmarried and in those who had multiple sexual partners. Women with simultaneous infection by HSV-1 and 2 had higher prevalence of HPV infection. The prevalence of HSV infection showed no association whatsoever with the risk factors analyzed and HSV-1 was the predominant type among the cases of genital HSV infection. The overall prevalence of C. Trachomatis was relatively low, thus providing greater value in younger women aged less than or equal to 20 years
As doen?as sexualmente transmiss?veis (DSTs) est?o entre os maiores problemas de sa?de p?blica, especialmente em pa?ses em desenvolvimento. A aquisi??o dessas infec??es durante o in?cio da atividade sexual ? freq?ente, por?m muitas dessas infec??es t?m curso benigno. Entretanto, em algumas o pat?geno permanecer em estado de lat?ncia podendo ser reativado e causar infec??o produtiva que podem evoluir para formas graves. Al?m disso, alguns delas se transmitem verticalmente, resultando em infec??o cong?nita, causando danos imediatos ou em longo prazo ? crian?a. Os fatores de risco cl?ssicos para agentes sexualmente transmiss?veis s?o: in?cio precoce da vida sexual e reprodutiva, m?ltiplos parceiros sexuais ao longo da vida, uso de contraceptivos orais e co-infec??es por diferentes pat?genos. N?s apresentados os resultados de um estudo transversal, que teve como objetivo, estimar a preval?ncia de infec??o genital pelo Papilomav?rus humano (HPV), pelo v?rus Herpes simples (HSV) e por Chlamydia trachomatis (CT) em um segmento da popula??o feminina da regi?o metropolitana de Natal, arroladas entre aquelas que procuraram voluntariamente, Unidades B?sicas de Sa?de para a realiza??o do exame de rastreamento do c?ncer de colo do ?tero no per?odo de 2008 a 2010. Todas as participantes, num total de 261 mulheres, responderam a um question?rio padronizado por meio do qual foram identificadas ?s caracter?sticas s?cio-demogr?ficas, fatores de risco cl?ssicos para DSTs, atividade sexual e reprodutiva e tabagismo. Foram obtidas duas amostras de cada paciente, uma destinada a realiza??o do exame citol?gico de Papanicolaou para a detec??o de altera??es celulares e a outra processada para a extra??o de DNA, e analisadas por PCR (rea??o em cadeia de polimerase) para a detec??o dos tr?s pat?genos estudados. A popula??o alvo do estudo foi composta por mulheres sexualmente ativas, com idade entre 13 e 79 anos, m?dia de 38,7 anos, sendo a maioria delas casadas, com baixo grau de instru??o e baixa renda. A maioria (87%) apresentou resultado normal no exame citol?gico e apenas 2,7% apresentaram altera??es citol?gicas de baixo grau. Foram encontradas taxas de preval?ncia de 37,9% para HPV, 4,6% para CT e 26% para o HSV. A preval?ncia do HPV foi maior nas mulheres com at? 25 anos, nas solteiras e naquelas que tiveram m?ltiplos parceiros sexuais. As mulheres com infec??o simult?nea por HSV-1 e 2 aprestaram maior preval?ncia de infec??o por HPV. A preval?ncia da infec??o pelo HSV n?o apresentou ind?cio de associa??o com os fatores de risco analisados e o HSV-1 foi o tipo predominante entre os casos de infec??o genital pelo HSV. A preval?ncia geral da C. Trachomatis foi relativamente baixa, apresentado maior valor nas mulheres mais jovens, com idade menor ou igual a 20 anos
Fusco, Pedro Ehrmann Brasiliense. "Invaginações (plicaturas) da grande curvatura gástrica e da parede anterior do estômago para controle de peso: modelos experimentais." Universidade de São Paulo, 2010. http://www.teses.usp.br/teses/disponiveis/5/5132/tde-10032010-114604/.
Full textBACKGROUND: Many bariatric endoscopic or surgical procedures performed today reduce gastric luminal volume, alone or in combination with a distal enteric intervention. A form of prosthetic wrap of the folded (or plicated) stomach was used in the past for treating obesity with a high rate of prosthesis-related reintervention. Nissen gastric fundoplication used in the treatment of gastroesophageal reflux disease induces a small but significant weight loss without gastric stapling, partitioning, or prosthesis-related morbidity. We hypothesized greater gastric curvature invagination would lead to weight loss in rats (first series of experiments named Set A). Once confirmed this hypothesis, we compared anterior gastric wall and greater gastric curvature invaginations for weight loss (second series of experiments - Set B). The anterior invagination would be technically easier as it would avoid mobilization of the greater omentum. METHODS: In Set A, 30 rats were randomly divided into 3 groups. 10 rats in the first group (A-CTRANEST) were anesthetized and weighed. The rats from the second group (ACTR- LAP) were in addition submitted to a laparotomy plus visceral manipulation. In the third group (A-INV-CURV), invagination of the greater curvature of the stomach was added. All animals were weighed on the 7th and 21st days. They were then autopsied on the 21st day. In Set B, 20 rats were randomized in 2 groups. The anterior gastric wall of 10 rats was invaginated in the first group (B-INV-ANT). The greater gastric curvature of 10 rats was invaginated in the second group (B-INV-CURV). All animals were weighed weekly for 4 weeks. They were then autopsied on the 28th day. RESULTS: In Set A, the mean body weight of the A-INV-CURV (311,41g) group became less than the A-CTR-LAP (346,18g) and A-CTR-ANEST (362,48) groups, p<0,001 (repeated measures ANOVA). The mean weight of the peritesticular fat pad from the A-INV-CURV group (4364mg) was also significantly less than from the A-CTR-ANEST group (5059mg), p<0,02 (Dunn test), the other peritesticular fat comparisons were indifferent. In Set B, the mean body weight of the B-INV-CURV group (341,90g) became less than the B-INV-ANT group (370,56g) at 21 days, p<0,03 (Tukeys adjustment). The mean weight of the peritesticular fat pad and the mean gastric volume were not different at 28 days (sacrifice). CONCLUSION: Greater gastric curvature invagination (plication) significantly reduces weight compared to isolated anesthesia, to anesthesia and laparotomy, and to anterior gastric wall invagination.
FARIAS, Julianna Santos. "DESENVOLVIMENTO DE UM SIMPLES E NOVO SENSOR PARA FLUTAMIDA À BASE DE NANOTUBOS DE CARBONO OXIDADO E ÓXIDO DE GRAFENO: APLICAÇÃO EM AMOSTRAS DE URINA ARTIFICIAL E FORMULAÇÕES FARMACÊUTICAS." Universidade Federal do Maranhão, 2017. http://tedebc.ufma.br:8080/jspui/handle/tede/1291.
Full textMade available in DSpace on 2017-04-12T15:30:06Z (GMT). No. of bitstreams: 1 Juliana Santos Farias.pdf: 1234303 bytes, checksum: 420e49b91acb05fb1346e95075411509 (MD5) Previous issue date: 2017-03-06
CAPES, FAPEMA,CNPQ
This paper describes the development of a simple and new sensor electrochemical determination of flutamide in voltamétrica formulations pharmaceutical and artificial urine specimens using a carbon electrode vitreous (ECV) modified with oxidized carbon nanotubes and graphene oxide (NCO-OG), which was named ECV/NCO-OG. Electronic microscopy techniques scanning (SEM) and Raman Spectroscopy were used for the characterization of carbon based materials. The electrochemical response of the analyte front of the ECV/NCO-OG was investigated by cyclic voltammetry techniques (VC) and square wave voltammetry (VOQ). The sensor exhibited a high activity eletrocatalítica for the reduction of flutamide in 0.05 V vs. Ag/AgCl. The parameters experimental influence the response of the electrode was investigated and the optimum conditions were found for the electrode modified with NCO-OG, in Britton-Robinson buffer solution-BR on concentration of 0.1 mol L-1 (pH 5). The proposed sensor presented a wide range of linear response of concentration for the flutamide of 0.1 to 1000 µmol L-1 (or µ g L-1 27.6 to 0.27 g L-1) for n = 15 (R2 = 0.997), limit of detection (LOD), limit of quantification (LOQ), and sensitivity of 0.03 µmol L-1, 0.1 µmol L-1, and 0.30 µmol µA -1 L, respectively. The ECV/NCO-OG was successfully applied to the determination of flutamide in pharmaceutical formulations used in the treatment of prostate cancer and artificial urine samples. The results obtained with the proposed sensor were compared with the method described in the literature and showed a level of 95% confidence, demonstrating that there is no statistical difference between the method of reference and the method proposed. The addition and recovery studies show that the proposed method presents a satisfactory accuracy with average value of 101% recovery ( 1)%. for the fortified samples.
Este trabalho descreve o desenvolvimento de um simples e novo sensor eletroquímico para determinação voltamétrica de flutamida em formulações farmacêuticas e amostras de urina artificial empregando um eletrodo de carbono vítreo (ECV) modificado com nanotubos de carbono oxidado e óxido de grafeno (NCO-OG), o qual foi denominado ECV/NCO-OG. As técnicas microscopia eletrônica de varredura (MEV) e a Espectroscopia Raman foram utilizadas para a caracterização dos materiais à base de carbono. A resposta eletroquímica do analito frente ao ECV/NCO-OG foi investigada através das técnicas de voltametria cíclica (VC) e voltametria de onda quadrada (VOQ). O sensor exibiu uma alta atividade eletrocatalítica para a redução da flutamida em 0,05 V vs Ag/AgCl. Os parâmetros experimentais que influenciam a resposta do eletrodo foram investigados e as condições ótimas foram encontradas para o eletrodo modificado com NCO-OG, em solução tampão Britton-Robinson-BR na concentração de 0,1 mol L-1 (pH 5). O sensor proposto apresentou uma ampla faixa de resposta linear de concentração para a flutamida de 0,1 a 1000 µmol L-1 (ou 27,6 µg L-1 a 0,27 g L-1) para n=15 (R2=0,997), com limite de detecção (LOD), limite de quantificação (LOQ), e sensibilidade de 0,03 µmol L-1, 0,1 µmol L-1, e 0,30 µA µmol-1 L, respectivamente. O ECV/NCO-OG foi aplicado com sucesso para a determinação de flutamida em formulações farmacêuticas utilizadas no tratamento de câncer de próstata e amostras de urina artificial. Os resultados obtidos com o sensor proposto foram comparados com o método descrito na literatura e observou-se um nível de confiança de 95%, demonstrando que não há diferença estatística entre o método de referência e o método proposto. Os estudos de adição e recuperação mostram que o método proposto apresenta uma exatidão satisfatória com valor médio de recuperação de 101% ( 1) %. para as amostras fortificadas.
Scarlato, Michele. "Sicurezza di rete, analisi del traffico e monitoraggio." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2012. http://amslaurea.unibo.it/3223/.
Full textHwang, Joe, and 黃守偉. "Automatic Graph Drawing for Simple Graphs." Thesis, 1998. http://ndltd.ncl.edu.tw/handle/62852007564092722674.
Full textChang, Chia-Yi, and 張嘉益. "Two Efficient Graph Representations for SimpleTwo Efficient Graph Representations for Simple Graphs." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/91938888012934084888.
Full text國立臺灣科技大學
資訊管理系
93
Representing graphs is a fundamental data-structuring problem. Adjacency matrices and adjacency lists are two well known representations. The operations on an adjacency matrix which contain adjacency test, inserting/deleting an edge can be done in constant time. However, finding all adjacency vertices of a given vertex will take θ(n) time by using an adjacent matrix. On the other hand, to test adjacency on adjacency lists will take O(deg(i)) time, where deg(i) is the degree of vertex i. In this thesis, we propose two efficient representations which not only support adjacency test in constant time, but also support the adjacency test of a given vertex in θ(deg(i)). Our representation will take θ(n2) time to initialize. However, inserting/deleting an edge only takes constant time. The proposed representations will be very efficient for the problems with a lot of inserting/deleting edge operations.
Papoutsakis, Ioannis. "Tree Spanners of Simple Graphs." Thesis, 2013. http://hdl.handle.net/1807/35920.
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