Journal articles on the topic 'Granzymes'
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Joeckel, Lars T., and Phillip I. Bird. "Are all granzymes cytotoxic in vivo?" Biological Chemistry 395, no. 2 (February 1, 2014): 181–202. http://dx.doi.org/10.1515/hsz-2013-0238.
Full textEbnet, K., C. N. Levelt, T. T. Tran, K. Eichmann, and M. M. Simon. "Transcription of granzyme A and B genes is differentially regulated during lymphoid ontogeny." Journal of Experimental Medicine 181, no. 2 (February 1, 1995): 755–63. http://dx.doi.org/10.1084/jem.181.2.755.
Full textHay, Zachary L. Z., and Jill E. Slansky. "Granzymes: The Molecular Executors of Immune-Mediated Cytotoxicity." International Journal of Molecular Sciences 23, no. 3 (February 6, 2022): 1833. http://dx.doi.org/10.3390/ijms23031833.
Full textGrossman, William J., James W. Verbsky, Benjamin L. Tollefsen, Claudia Kemper, John P. Atkinson, and Timothy J. Ley. "Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells." Blood 104, no. 9 (November 1, 2004): 2840–48. http://dx.doi.org/10.1182/blood-2004-03-0859.
Full textZeberg, Lennart, and Tor Olofsson. "Differential Expression of Granzymes A and K in Subsets of Human T-Cells and NK-Cells." Blood 106, no. 11 (November 16, 2005): 3917. http://dx.doi.org/10.1182/blood.v106.11.3917.3917.
Full textCao, Xuefang, Paula A. Revell, William J. Grossman, Dori A. Thomas, Zhi Hong Lu, and Timothy J. Ley. "Orphan Granzymes Downstream from Granzyme B Are Important for Tumor Clearance In Vivo and in Vitro." Blood 104, no. 11 (November 16, 2004): 2653. http://dx.doi.org/10.1182/blood.v104.11.2653.2653.
Full textKaiserman, Dion, Catherina H. Bird, Jiuru Sun, Antony Matthews, Kheng Ung, James C. Whisstock, Philip E. Thompson, Joseph A. Trapani, and Phillip I. Bird. "The major human and mouse granzymes are structurally and functionally divergent." Journal of Cell Biology 175, no. 4 (November 20, 2006): 619–30. http://dx.doi.org/10.1083/jcb.200606073.
Full textThiery, Jerome, Dennis Keefe, Saviz Saffarian, Denis Martinvalet, Michael Walch, Emmanuel Boucrot, Tomas Kirchhausen, and Judy Lieberman. "Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis." Blood 115, no. 8 (February 25, 2010): 1582–93. http://dx.doi.org/10.1182/blood-2009-10-246116.
Full textNakajima, H., H. L. Park, and P. A. Henkart. "Synergistic roles of granzymes A and B in mediating target cell death by rat basophilic leukemia mast cell tumors also expressing cytolysin/perforin." Journal of Experimental Medicine 181, no. 3 (March 1, 1995): 1037–46. http://dx.doi.org/10.1084/jem.181.3.1037.
Full textGriffiths, G. M., and S. Isaaz. "Granzymes A and B are targeted to the lytic granules of lymphocytes by the mannose-6-phosphate receptor." Journal of Cell Biology 120, no. 4 (February 15, 1993): 885–96. http://dx.doi.org/10.1083/jcb.120.4.885.
Full textLoh, Joy, Dori A. Thomas, Paula A. Revell, Timothy J. Ley, and Herbert W. Virgin. "Granzymes and Caspase 3 Play Important Roles in Control of Gammaherpesvirus Latency." Journal of Virology 78, no. 22 (November 15, 2004): 12519–28. http://dx.doi.org/10.1128/jvi.78.22.12519-12528.2004.
Full textWeston, G. Scott, and Robert D. Sindelar. "Granzymes as Potential Targets for Rational Drug Design." Current Medicinal Chemistry 3, no. 1 (February 1996): 37–46. http://dx.doi.org/10.2174/092986730301220224163207.
Full textYarosh, I. V., V. A. Misyurin, and I. I. Krasnyuk. "NOVEL IMMUNOTHERAPEUTIC TARGETED GRANZYME DELIVERY SYSTEMS IN TREATMENT OF MALIGNANT TUMORS." Russian Journal of Biotherapy 20, no. 2 (July 14, 2021): 31–41. http://dx.doi.org/10.17650/1726-9784-2021-20-2-31-41.
Full textNakajima, H., P. Golstein, and P. A. Henkart. "The target cell nucleus is not required for cell-mediated granzyme- or Fas-based cytotoxicity." Journal of Experimental Medicine 181, no. 5 (May 1, 1995): 1905–9. http://dx.doi.org/10.1084/jem.181.5.1905.
Full textPrunk, Mateja, Milica Perisic Nanut, Jerica Sabotic, Urban Svajger, and Janko Kos. "Increased cystatin F levels correlate with decreased cytotoxicity of cytotoxic T cells." Radiology and Oncology 53, no. 1 (March 3, 2019): 57–68. http://dx.doi.org/10.2478/raon-2019-0007.
Full textMacIvor, Debra M., Christine T. N. Pham, and Timothy J. Ley. "The 5′ Flanking Region of the Human Granzyme H Gene Directs Expression to T/Natural Killer Cell Progenitors and Lymphokine-Activated Killer Cells in Transgenic Mice." Blood 93, no. 3 (February 1, 1999): 963–73. http://dx.doi.org/10.1182/blood.v93.3.963.
Full textMacIvor, Debra M., Christine T. N. Pham, and Timothy J. Ley. "The 5′ Flanking Region of the Human Granzyme H Gene Directs Expression to T/Natural Killer Cell Progenitors and Lymphokine-Activated Killer Cells in Transgenic Mice." Blood 93, no. 3 (February 1, 1999): 963–73. http://dx.doi.org/10.1182/blood.v93.3.963.403k18_963_973.
Full textRönnberg, Elin, Gabriela Calounova, Bengt Guss, Anders Lundequist, and Gunnar Pejler. "Granzyme D Is a Novel Murine Mast Cell Protease That Is Highly Induced by Multiple Pathways of Mast Cell Activation." Infection and Immunity 81, no. 6 (March 25, 2013): 2085–94. http://dx.doi.org/10.1128/iai.00290-13.
Full textWaterhouse, Nigel J., Vivien R. Sutton, Karin A. Sedelies, Annette Ciccone, Misty Jenkins, Stephen J. Turner, Phillip I. Bird, and Joseph A. Trapani. "Cytotoxic T lymphocyte–induced killing in the absence of granzymes A and B is unique and distinct from both apoptosis and perforin-dependent lysis." Journal of Cell Biology 173, no. 1 (April 10, 2006): 133–44. http://dx.doi.org/10.1083/jcb.200510072.
Full textVeugelers, Kirstin, Bruce Motyka, Christine Frantz, Irene Shostak, Tracy Sawchuk, and R. Chris Bleackley. "The granzyme B–serglycin complex from cytotoxic granules requires dynamin for endocytosis." Blood 103, no. 10 (May 15, 2004): 3845–53. http://dx.doi.org/10.1182/blood-2003-06-2156.
Full textJohnson, Hillary, Luca Scorrano, Stanley J. Korsmeyer, and Timothy J. Ley. "Cell death induced by granzyme C." Blood 101, no. 8 (April 15, 2003): 3093–101. http://dx.doi.org/10.1182/blood-2002-08-2485.
Full textYamanaka, Gaku, Shinichiro Morichi, Tomoko Takamatsu, Ryou Takahashi, Yusuke Watanabe, Yu Ishida, Mika Takeshita, et al. "Granzyme A Participates in the Pathogenesis of Infection-Associated Acute Encephalopathy." Journal of Child Neurology 35, no. 3 (November 11, 2019): 208–14. http://dx.doi.org/10.1177/0883073819886217.
Full textCasciola-Rosen, Livia, Margarita Garcia-Calvo, Herbert G. Bull, Joseph W. Becker, Tonie Hines, Nancy A. Thornberry, and Antony Rosen. "Mouse and Human Granzyme B Have Distinct Tetrapeptide Specificities and Abilities to Recruit the Bid Pathway." Journal of Biological Chemistry 282, no. 7 (December 19, 2006): 4545–52. http://dx.doi.org/10.1074/jbc.m606564200.
Full textZhou, Zhiwei, Huabin He, Kun Wang, Xuyan Shi, Yupeng Wang, Ya Su, Yao Wang, et al. "Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells." Science 368, no. 6494 (April 16, 2020): eaaz7548. http://dx.doi.org/10.1126/science.aaz7548.
Full textKiselevsky, D. B. "Granzymes and Mitochondria." Biochemistry (Moscow) 85, no. 2 (February 2020): 131–39. http://dx.doi.org/10.1134/s0006297920020017.
Full textDressel, Ralf, Srikumar M. Raja, Stefan Höning, Tim Seidler, Christopher J. Froelich, Kurt von Figura, and Eberhard Günther. "Granzyme-mediated Cytotoxicity Does Not Involve the Mannose 6-Phosphate Receptors on Target Cells." Journal of Biological Chemistry 279, no. 19 (February 25, 2004): 20200–20210. http://dx.doi.org/10.1074/jbc.m313108200.
Full textBalkow, Sandra, Astrid Kersten, Thi Thanh Thao Tran, Thomas Stehle, Philipp Grosse, Crisan Museteanu, Olaf Utermöhlen, et al. "Concerted Action of the FasL/Fas and Perforin/Granzyme A and B Pathways Is Mandatory for the Development of Early Viral Hepatitis but Not for Recovery from Viral Infection." Journal of Virology 75, no. 18 (September 15, 2001): 8781–91. http://dx.doi.org/10.1128/jvi.75.18.8781-8791.2001.
Full textBrowne, Kylie A., Elizabeth Blink, Vivien R. Sutton, Christopher J. Froelich, David A. Jans, and Joseph A. Trapani. "Cytosolic Delivery of Granzyme B by Bacterial Toxins: Evidence that Endosomal Disruption, in Addition to Transmembrane Pore Formation, Is an Important Function of Perforin." Molecular and Cellular Biology 19, no. 12 (December 1, 1999): 8604–15. http://dx.doi.org/10.1128/mcb.19.12.8604.
Full textBots, M., and J. P. Medema. "Granzymes at a glance." Journal of Cell Science 119, no. 24 (December 15, 2006): 5011–14. http://dx.doi.org/10.1242/jcs.03239.
Full textHwang, Joo-Hee, Jeong-Hwan Hwang, and Chang-Seop Lee. "Elevated Extracellular Levels of Granzymes in Patients with Scrub Typhus." American Journal of Tropical Medicine and Hygiene 105, no. 6 (December 1, 2021): 1680–83. http://dx.doi.org/10.4269/ajtmh.20-1369.
Full textWensink, Annette C., C. Erik Hack, and Niels Bovenschen. "Granzymes Regulate Proinflammatory Cytokine Responses." Journal of Immunology 194, no. 2 (January 2, 2015): 491–97. http://dx.doi.org/10.4049/jimmunol.1401214.
Full textBovenschen, Niels, and J. Alain Kummer. "Orphan granzymes find a home." Immunological Reviews 235, no. 1 (April 28, 2010): 117–27. http://dx.doi.org/10.1111/j.0105-2896.2010.00889.x.
Full textRomero, V., and F. Andrade. "Non-apoptotic functions of granzymes." Tissue Antigens 71, no. 5 (May 2008): 409–16. http://dx.doi.org/10.1111/j.1399-0039.2008.01013.x.
Full textSower, Laurie E., Gary R. Klimpel, William Hanna, and Christopher J. Froelich. "Extracellular Activities of Human Granzymes." Cellular Immunology 171, no. 1 (July 1996): 159–63. http://dx.doi.org/10.1006/cimm.1996.0187.
Full textEwen, C. L., K. P. Kane, and R. C. Bleackley. "A quarter century of granzymes." Cell Death & Differentiation 19, no. 1 (November 4, 2011): 28–35. http://dx.doi.org/10.1038/cdd.2011.153.
Full textKaiserman, D., and P. I. Bird. "Control of granzymes by serpins." Cell Death & Differentiation 17, no. 4 (November 6, 2009): 586–95. http://dx.doi.org/10.1038/cdd.2009.169.
Full textCullen, S. P., M. Brunet, and S. J. Martin. "Granzymes in cancer and immunity." Cell Death & Differentiation 17, no. 4 (January 15, 2010): 616–23. http://dx.doi.org/10.1038/cdd.2009.206.
Full textChen, G., L. Shi, D. W. Litchfield, and A. H. Greenberg. "Rescue from granzyme B-induced apoptosis by Wee1 kinase." Journal of Experimental Medicine 181, no. 6 (June 1, 1995): 2295–300. http://dx.doi.org/10.1084/jem.181.6.2295.
Full textFeehan, David D., Khusraw Jamil, Maria J. Polyak, Henry Ogbomo, Mark Hasell, Shu Shun LI, Richard F. Xiang, et al. "Natural killer cells kill extracellular Pseudomonas aeruginosa using contact-dependent release of granzymes B and H." PLOS Pathogens 18, no. 2 (February 24, 2022): e1010325. http://dx.doi.org/10.1371/journal.ppat.1010325.
Full textSattar, Rabia, S. Abid Ali, and Atiya Abbasi. "Bioinformatics of granzymes: sequence comparison and structural studies on granzyme family by homology modeling." Biochemical and Biophysical Research Communications 308, no. 4 (September 2003): 726–35. http://dx.doi.org/10.1016/s0006-291x(03)01458-x.
Full textDutta, Dibyendu, In Park, Hiwot Guililat, Samuel Sang, Arpita Talapatra, Barkha Singhal, and Nathaniel C. Mills. "Testosterone regulates granzyme K expression in rat testes." Endocrine Regulations 51, no. 4 (October 26, 2017): 193–204. http://dx.doi.org/10.1515/enr-2017-0020.
Full textPączek, Sara, Marta Łukaszewicz-Zając, and Barbara Mroczko. "Granzymes—Their Role in Colorectal Cancer." International Journal of Molecular Sciences 23, no. 9 (May 9, 2022): 5277. http://dx.doi.org/10.3390/ijms23095277.
Full textAndzelm, Milena M., Xi Chen, Konrad Krzewski, Jordan S. Orange, and Jack L. Strominger. "Myosin IIA is required for cytolytic granule exocytosis in human NK cells." Journal of Experimental Medicine 204, no. 10 (September 17, 2007): 2285–91. http://dx.doi.org/10.1084/jem.20071143.
Full textFutas, Ján, Jan Oppelt, Pamela Anna Burger, and Petr Horin. "A Deadly Cargo: Gene Repertoire of Cytotoxic Effector Proteins in the Camelidae." Genes 12, no. 2 (February 21, 2021): 304. http://dx.doi.org/10.3390/genes12020304.
Full textFehniger, Todd A., Sheng F. Cai, Xuefang Cao, Andrew J. Bredemeyer, Rachel M. Presti, Anthony R. French, and Timothy James Ley. "Murine NK Cells Require Activation-Dependent Expression of Granzyme B and Perforin To Become Potent Cytotoxic Effectors." Blood 108, no. 11 (November 16, 2006): 920. http://dx.doi.org/10.1182/blood.v108.11.920.920.
Full textVahedi, Fatemeh, Nya Fraleigh, Caitlyn Vlasschaert, Janet McElhaney, and Pejman Hanifi-Moghaddam. "Human granzymes: Related but far apart." Medical Hypotheses 83, no. 6 (December 2014): 688–93. http://dx.doi.org/10.1016/j.mehy.2014.09.019.
Full textSalvesen, G. "Cytosolic protease cascades: activation by granzymes." Biochemistry and Cell Biology 75, no. 4 (August 1, 1997): 475. http://dx.doi.org/10.1139/abstract26.
Full textMartinvalet, Denis, and Jérôme Thiery. "Comment les granzymes tuent leurs cibles." médecine/sciences 24, no. 11 (November 2008): 901–3. http://dx.doi.org/10.1051/medsci/20082411901.
Full textGranville, D. J. "Granzymes in disease: bench to bedside." Cell Death & Differentiation 17, no. 4 (March 15, 2010): 565–66. http://dx.doi.org/10.1038/cdd.2009.218.
Full textZeglinski, Matthew R., and David J. Granville. "Granzymes in cardiovascular injury and disease." Cellular Signalling 76 (December 2020): 109804. http://dx.doi.org/10.1016/j.cellsig.2020.109804.
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