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1

G, Gubernatis, ed. Acute rejection of liver grafts. Austin: R.G. Landes, 1993.

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2

1946-, Solez Kim, Racusen Lorraine C. 1948-, and Billingham Margaret E. 1930-, eds. Solid organ transplant rejection: Mechanisms, pathology, and diagnosis. New York: Marcel Dekker, Inc., 1996.

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3

Brough, Stephen James Simon. The routes of sensitization in graft rejection. Birmingham: University of Birmingham, 1989.

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4

Hill, John Clifford. The mechanism and management of corneal graft rejection. Amsterdam: Kugler, 1996.

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5

1948-, Racusen Lorraine C., Solez Kim 1946-, and Burdick James F. 1941-, eds. Kidney transplant rejection: Diagnosis and treatment. 3rd ed. New York: M. Dekker, 1998.

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6

1941-, Burdick James F., ed. Kidney transplant rejection: Diagnosis and treatment. 2nd ed. New York: Dekker, 1992.

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7

Conference on Transplantation and Clinical Immunology (28th 1996). Late graft loss: Proceedings of the 28th Conference on Transplantation and Clinical Immunology, 3-5 June, 1996. Dordrecht: Kluwer Academic Publishers, 1997.

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8

1949-, Orosz Charles G., Sedmak Daniel D, and Ferguson Ronald M, eds. Transplant vascular sclerosis. Austin: R.G. Landes, 1995.

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9

Green, Colin. Recent progress in organ transplantation. Oxford: Medicine Group for the Medicine Publishing Foundation, 1988.

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10

1926-, Starzl Thomas E., and Thomson Angus W, eds. Immunosuppressive drugs: Developments in anti-rejection therapy. London: Edward Arnold, 1994.

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11

W, Thomson Angus, and Starzl Thomas E. 1926-, eds. Immunosuppressive drugs: Developments in anti-rejection therapy. London: E. Arnold, 1994.

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12

Johnsson, Cecilia. Graft-versus-host reaction and rejection after experimental small-bowel transplantation. Uppsala: University of Uppsala, 1994.

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13

Van den Elsen, Peter J., 1951-. The human T-cell receptor repertoire and transplantation. New York: Springer Verlag, 1995.

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14

J, Kemnitz, ed. Diagnosis of rejection in biopsy material of cardiac allografts: Histopathology and immunohistology. Lengerich: Wolfgang Pabst Verlag, 1991.

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15

Banf Conference on Allograft Pathology (4th 1997 Banf, Alberta, Canada). Fourth BANFF Conference on Allograft Pathology. [New York?]: Churchill Livingstone, 1998.

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16

Meeting, International Society for Applied Cardiovascular Biology. Applied cardiovascular biology, 1990-91. Basel: Karger, 1992.

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17

R, Salaman John, and Royal Society of Medicine (Great Britain)., eds. Long-term cyclosporin therapy and risk of chronic rejection: A discussion. London: Royal Society of Medicine Press, 1994.

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18

Kelso, Anne. Cytokines in transplantation. Austin: R.G. Landes, 1996.

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19

C, Kolbeck Peter, Markin Rodney S, McManus Bruce M, and Costanzo-Nordin Maria R, eds. Transplant pathology. Chicago: ASCP Press, 1994.

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20

Donna, Przepiorka, ed. New immunosuppressive drugs. Glenview, Ill. (P.O. Box 435, Glenview 60025): Physicians & Scientists Pub. Co., 1994.

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21

Y, Shin Alexander, and Moran Steven L, eds. Vascularized bone grafting in orthopedic surgery. Philadelphia: Saunders, 2006.

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22

M, Ferguson Ronald, and Sommer Bruce G, eds. The Clinical management of the renal transplant recipient with cyclosporine. Orlando: Grune & Stratton, 1986.

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23

Buckley, John Graham. Experimental studies on the role of major and minor histocompatibility antigens in graft rejection. Birmingham: University of Birmingham, 1986.

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24

Ariela, Benigni, and Remuzzi Giuseppe, eds. Gene therapy for renal diseases and transplantation. Basel: Karger, 2008.

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25

Alexander, J. Wesley. Transplantation tolerance induction. New York: Springer, 1996.

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26

Nessralla, Laurie-Ann. Incidence of rejection, morbidity, mortality and graft function in renal transplant recipients following cyclosporine to azathioprine switch. [New Haven: s.n.], 1990.

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27

Sigurd, Nitter-Hauge, Allison David J, and Hartnell George G, eds. Cardiac imaging: X-ray, MR, and ultrasound :proceedings of the Nycomed Scientific Symposium 1990 held in Bergen, 8-9 October 1990. Amsterdam: Excerpta Medica, 1991.

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28

Conference on Transplantation and Clinical Immunology (29th 1997). Retransplantation: Proceedings of the 29th Conference on Transplantation and Clinical Immunology, 9-11 June 1997. Dordrecht: Kluwer Academic Publishers, 1998.

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29

Rossmann, Pavel. Renal allograft biopsy: Image, interpretation, interventions. Praha: Academia, 1997.

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30

C, Paul Leendert, and Solez Kim 1946-, eds. Organ transplantation: Long-term results. New York: Marcel Dekker, 1992.

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31

Jong-Tieben, Linda M. de. Human papillomavirus infection and skin cancer in renal transplant recipients. Leiden: University of Leiden, 1998.

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32

T, Mohanakumar, ed. The role of MHC and non-MHC antigens in allograft immunity. Austin: R.G. Landes Co., 1994.

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33

C, Ponticelli, and De Vecchi A, eds. Ciclosporin in renal transplantation. Basel: Karger, 1986.

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34

Thayer, Meryman Harold, ed. Transplantation: Approaches to graft rejection : proceedings of the XVIII Annual Scientific Symposium of the American Red Cross, Washington, DC, April 28-30, 1986. New York: Liss, 1986.

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35

Britain), Medicine Group (Great, and Sandoz Pharmaceuticals, eds. Cyclosporin: Five years on : proceedings of a workshop held at the Belfry Hotel, Wishaw, UK, May 1988. Oxford, UK: Medicine Group (UK) Ltd., 1989.

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36

Leonard, Vaughan Christopher, ed. Biomechanics of sport. Boca Raton, Fla: CRC Press, 1989.

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37

Philip, Hornick, and Rose Marlene L, eds. Transplantation immunology: Methods and protocols. Totowa, N.J: Humana Press, 2006.

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38

van, Schilfgaarde R., and Hardy Mark A. 1938-, eds. Transplantation of the endocrine pancreas in diabetes mellitus. Amsterdam: Elsevier, 1988.

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39

D, Galmarini, ed. Drugs and the liver: High risk patients and transplantation. Dordrecht: Kluwer Academic Publishers, 1993.

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40

Oremus, Mark. Utility of monitoring mycophenolic acid in solid organ transplant patients. Rockville, MD: Agency for Healthcare Research and Quality, 2008.

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41

1968-, Oremus Mark, Zeidler Johannes, and United States. Agency for Healthcare Research and Quality., eds. Utility of monitoring mycophenolic acid in solid organ transplant patients. Rockville, MD: Agency for Healthcare Research and Quality, 2008.

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42

1968-, Oremus Mark, Zeidler Johannes, and United States. Agency for Healthcare Research and Quality., eds. Utility of monitoring mycophenolic acid in solid organ transplant patients. Rockville, MD: Agency for Healthcare Research and Quality, 2008.

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43

Matthias, Gottmann, and United States. National Aeronautics and Space Administration., eds. Thermal control systems for low-temperature heat rejection on a lunar base: Semiannual status report for grant NAG5-1572. Tucson, AZ: Dept. of Aerospace and Mechanical Engineering, University of Arizona, 1992.

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44

Matthias, Gottmann, Nanjundan Ashok, and Goddard Space Flight Center, eds. Thermal control systems for low-temperature heat rejection on a lunar base: Annual progress report for grant NAG5-1572 (MOD). [Tucson, Ariz.?]: Aerospace and Mechanical Engineering, University of Arizona, 1993.

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45

Matthias, Gottmann, Nanjundan Ashok, and Goddard Space Flight Center, eds. Thermal control systems for low-temperature heat rejection on a lunar base: Annual progress report for grant NAG5-1572 (MOD). [Tucson, Ariz.?]: Aerospace and Mechanical Engineering, University of Arizona, 1993.

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46

Hyperacute xenograft rejection. New York: Springer-Verlag, 1995.

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47

MERRYMAN, HT. Meryman: Transplantation - Approaches to Graft Rejection. John Wiley & Sons Inc, 1986.

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48

Cardiac Allograft Rejection. Springer, 2001.

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49

Dec, G. William, Jagat Narula, Ignasi Carrio, and Manel Ballester. Cardiac Allograft Rejection. Springer London, Limited, 2012.

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50

Rush, David N., and Peter W. Nickerson. Rejection. Edited by Jeremy R. Chapman. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0283_update_001.

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Abstract:
Rejection of the transplanted kidney is an important cause of graft loss despite modern cross-matching techniques and immunosuppressive agents. The incidence of acute rejection episodes in the first post-transplant year is down to less than 15% in low-risk recipients, but as many as one-third of allograft losses over 10 years result from alloimmunity. Rejection may occur at any time following transplantation, from minutes—hyperacute, to days—acute, or in the longer term—chronic. Rejection can be predominantly through either T-cell-mediated or antibody-mediated mechanisms. It may present clinically as either abrupt or insidious dysfunction of the graft, or it may be subclinical and thus silent, detected only by protocol biopsy or other technology. The prevention and treatment of T-cell-mediated rejection is usually successful with current immunosuppressive agents. Antibody-mediated rejection, on the other hand, is not easily treated and is the principal cause of late renal allograft loss. This chapter presents the concepts and details of this central issue in clinical transplantation.
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