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Author: Grafiati
Published: 7 July 2024

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1

VEGNA, V., V. BELLINI, J. P. BOCQUET, L. CASANO, A. D'ANGELO, R. DI SALVO, A. FANTINI, et al. "ω PHOTOPRODUCTION AT GRAAL." International Journal of Modern Physics E 19, no. 05n06 (June 2010): 1241–48. http://dx.doi.org/10.1142/s0218301310015734.

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The study of meson photoproduction on the nucleon is a very important tool to complete the puzzle of baryon excited states. GRAAL aim is the measurement of cross sections and of beam asymmetries for all the photonuclear reactions accessible in the energy range from 600 MeV up to 1.5 GeV. In the following preliminary results of the Σ beam asymmetry for ω photoproduction on the free proton in Hydrogen and on the quasi-free nucleon in Deuterium are shown. GRAAL is the first experiment in which both the charged and the radiative decay of ω meson are studied. Since the beam asymmetry is independent of the decay mode, the comparison of the results from the two channel allows an important check on data consistency. Results on the free proton are in good agreement with theoretical prediction from Zhao model and confirm the presence of P13(1720) state. The analysis performed for the radiative decay is applied to the process of ω photoproduction on the quasi free nucleon in Deuterium.
2

Tiator, L., M. Gorchtein, V. Kashevarov, K. Nikonov, M. Ostrick, M. Hadžimehmedović, R. Omerović, H. Osmanović, J. Stahov, and A. Švarc. "Eta and Etaprime Photoproduction on the Nucleon with the Isobar Model EtaMAID2018." EPJ Web of Conferences 199 (2019): 01019. http://dx.doi.org/10.1051/epjconf/201919901019.

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The isobar model EtaMAID has been updated with new and high precision data for η and η′ photoproduction on protons and neutrons from MAMI, ELSA, GRAAL and CLAS. The background is described in a recently developed Regge-cut model, and for the resonance part the whole list of nucleon resonances has been investigated with 21 N* states contributing to η photoproduction and 12 N* states contributing to η′ photoproduction. Finally, the possibility of a narrow resonance near W = 1900 MeV is discussed, that would be able to explain unexpected energy and angular dependence of observables in p(γ, η′)p near η threshold.
3

Rieke, Peter C., Sebastien Kerisit, Joseph V. Ryan, and James J. Neeway. "Adaptation of the GRAAL model of Glass Reactivity to accommodate non-linear diffusivity." Journal of Nuclear Materials 512 (December 2018): 79–93. http://dx.doi.org/10.1016/j.jnucmat.2018.09.058.

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Frugier, P., S. Gin, Y. Minet, T. Chave, B. Bonin, N. Godon, J. E. Lartigue, et al. "SON68 nuclear glass dissolution kinetics: Current state of knowledge and basis of the new GRAAL model." Journal of Nuclear Materials 380, no. 1-3 (October 2008): 8–21. http://dx.doi.org/10.1016/j.jnucmat.2008.06.044.

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Frugier, P., T. Chave, S. Gin, and J. E. Lartigue. "Application of the GRAAL model to leaching experiments with SON68 nuclear glass in initially pure water." Journal of Nuclear Materials 392, no. 3 (August 2009): 552–67. http://dx.doi.org/10.1016/j.jnucmat.2009.04.024.

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6

Drouet, J. L., and L. Pagès. "GRAAL: a model of GRowth, Architecture and carbon ALlocation during the vegetative phase of the whole maize plant." Ecological Modelling 165, no. 2-3 (July 2003): 147–73. http://dx.doi.org/10.1016/s0304-3800(03)00072-3.

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Minet, Y., B. Bonin, S. Gin, and P. Frugier. "Analytic implementation of the GRAAL model: Application to a R7T7-type glass package in a geological disposal environment." Journal of Nuclear Materials 404, no. 3 (September 2010): 178–202. http://dx.doi.org/10.1016/j.jnucmat.2010.07.015.

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Drouet, Jean-Louis, and Loïc Pagès. "GRAAL-CN: A model of GRowth, Architecture and ALlocation for Carbon and Nitrogen dynamics within whole plants formalised at the organ level." Ecological Modelling 206, no. 3-4 (August 2007): 231–49. http://dx.doi.org/10.1016/j.ecolmodel.2007.03.036.

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9

Lillington, Joseph N. P., Thomas L. Goût, Mike T. Harrison, Tajudeen M. Iwalewa, and Ian Farnan. "Assessing the effect of radioactive waste glass dissolution on early-stage radionuclide migration using simplified geological repository Monte Carlo transport models." MRS Advances 6, no. 4-5 (January 28, 2021): 73–79. http://dx.doi.org/10.1557/s43580-021-00009-0.

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AbstractThe vitrification of radioactive waste within glass and subsequent disposal within a geological disposal facility (GDF) requires a comprehensive understanding of the effect of glass dissolution on GDF performance. This paper aims to analyse the effect of both high-level and intermediate-level waste (HLW and ILW) glass dissolution source terms on radionuclide release into the geosphere just above the disposal vault (the ‘crown’). Radionuclide migration was simulated in GoldSim for HLW in either granite or clay host rocks with a bentonite buffer using carbon steel or copper canisters, whereas ILW simulations considered either granite or clay host rocks, in either bentonite buffer or cement backfill, using concrete or cast-iron canisters. Glass dissolution source terms were varied by coupling GoldSim and MATLAB to modify the initial, residual, and resumption dissolution rates of the glass or by applying the analytical GRAAL model to glass dissolution. HLW glass results indicate no preference of granite over clay host rocks for a given canister type but that a copper canister is preferable to steel. ILW results suggest that a granite–bentonite–cast-iron environment yields lowest crown activities with cast-iron preferable to concrete as the canister, bentonite preferable to cement as the buffer/backfill, and granite preferable to clay as the host rock. Varying glass dissolution source terms (initial, residual, and resumption dissolution rates) had an understood effect on radionuclide migration, although changes were arguably insignificant considering peak crown activity for both HLW and ILW.
10

Kankare, E., A. Efstathiou, R. Kotak, E. C. Kool, T. Kangas, D. O’Neill, S. Mattila, et al. "Core-collapse supernova subtypes in luminous infrared galaxies." Astronomy & Astrophysics 649 (May 2021): A134. http://dx.doi.org/10.1051/0004-6361/202039240.

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The fraction of core-collapse supernovae (CCSNe) occurring in the central regions of galaxies is not well constrained at present. This is partly because large-scale transient surveys operate at optical wavelengths, making it challenging to detect transient sources that occur in regions susceptible to high extinction factors. Here we present the discovery and follow-up observations of two CCSNe that occurred in the luminous infrared galaxy (LIRG) NGC 3256. The first, SN 2018ec, was discovered using the ESO HAWK-I/GRAAL adaptive optics seeing enhancer, and was classified as a Type Ic with a host galaxy extinction of AV = 2.1−0.1+0.3 mag. The second, AT 2018cux, was discovered during the course of follow-up observations of SN 2018ec, and is consistent with a subluminous Type IIP classification with an AV = 2.1 ± 0.4 mag of host extinction. A third CCSN, PSN J10275082−4354034 in NGC 3256, was previously reported in 2014, and we recovered the source in late-time archival Hubble Space Telescope imaging. Based on template light curve fitting, we favour a Type IIn classification for it with modest host galaxy extinction of AV = 0.3−0.3+0.4 mag. We also extend our study with follow-up data of the recent Type IIb SN 2019lqo and Type Ib SN 2020fkb that occurred in the LIRG system Arp 299 with host extinctions of AV = 2.1−0.3+0.1 and AV = 0.4−0.2+0.1 mag, respectively. Motivated by the above, we inspected, for the first time, a sample of 29 CCSNe located within a projected distance of 2.5 kpc from the host galaxy nuclei in a sample of 16 LIRGs. We find, if star formation within these galaxies is modelled assuming a global starburst episode and normal IMF, that there is evidence of a correlation between the starburst age and the CCSN subtype. We infer that the two subgroups of 14 H-poor (Type IIb/Ib/Ic/Ibn) and 15 H-rich (Type II/IIn) CCSNe have different underlying progenitor age distributions, with the H-poor progenitors being younger at 3σ significance. However, we note that the currently available sample sizes of CCSNe and host LIRGs are small, and the statistical comparisons between subgroups do not take into account possible systematic or model errors related to the estimated starburst ages.
11

Nurieva, Roza, Shuling Zheng, Wei Jin, Shao-Cong Sun, Guillermina Lozano, and Chen Dong. "A critical role of GRAIL in T cell activation and tolerance (50.18)." Journal of Immunology 184, no. 1_Supplement (April 1, 2010): 50.18. http://dx.doi.org/10.4049/jimmunol.184.supp.50.18.

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Abstract T lymphocyte activation is tightly regulated to ensure effective elimination of invading pathogens as well as maintaining tolerance against self-tissues. Gene related to anergy in lymphocytes (GRAIL) is a type I transmembrane protein localized to endosomal compartment with homology to RING finger proteins whose expression was previously associated with induction of T cell tolerance in vitro. In order to understand the physiological function of GRAIL in immune regulation, we have generated and analyzed a Grail-deficient mouse model. We found that naïve T cells lacking GRAIL exhibited greatly enhanced proliferation and cytokine production after TcR activation and did not depend on CD28 and ICOS for their effector cytokine expression. We also determined that lack of GRAIL abrogated suppressive function of regulatory T cells. Both naïve and regulatory T cells from Grail-deficient mice were less efficient in down-regulation of their TcR/CD3 expression. In vivo, Grail-deficient mice were resistant to immune tolerance induction and when compared to the wild-type mice, exhibited greater susceptibility to autoimmune diseases. Our results thus indicate GRAIL as an essential regulator of T cell tolerance by regulating naïve T cell tolerance and regulatory T cell function.
12

Kim, Jung-Woo, Jeong-Han Kim, Won-Hyeok Choe, So-Young Kwon, and Byung-Chul Yoo. "MELD-GRAIL-Na Is a Better Predictor of Mortality Than MELD in Korean Patients with Cirrhosis." Medicina 59, no. 3 (March 16, 2023): 592. http://dx.doi.org/10.3390/medicina59030592.

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Background and Objectives: The Child–Pugh (CP) score and Model for End-Stage Liver Disease (MELD) are classical systems for predicting mortality in patients with liver cirrhosis (LC). The MELD-GFR assessment in liver disease–sodium (MELD-GRAIL-Na) was designed to better reflect renal function and, therefore, provide better mortality predictions. This study aimed to compare the prediction accuracy of MELD-GRAIL-Na compared to CP and MELD in predicting short-term (1- and 3-month) mortality in Korean patients. Materials and Methods: Medical records of patients with LC admitted to the Konkuk University Hospital from 2015 to 2020 were retrospectively reviewed. Predictive values of the CP, MELD, and MELD-GRAIL-Na for 1-month and 3-month mortality were calculated using the area under the receiver operating curve (AUROC) and were compared using DeLong’s test. Results: In total, 1249 patients were enrolled; 102 died within 1 month, and 146 within 3 months. AUROCs of CP, MELD, and MELD-GRAIL-Na were 0.831, 0.847, and 0.857 for 1-month mortality and 0.837, 0.827, and 0.835 for 3-month mortality, respectively, indicating no statistical significance. For patients with CP classes B and C, AUROCs of CP, MELD, and MELD-GRAIL-Na were 0.782, 0.809, and 0.825 for 1-month mortality and 0.775, 0.769, and 0.786 for 3-month mortality, respectively. There was a significant difference between CP and MELD-GRAIL-Na in predicting 1-month mortality (p = 0.0428) and between MELD and MELD-GRAIL-Na in predicting 1-month (p = 0.0493) and 3-month mortality (p = 0.0225). Conclusions: Compared to CP and MELD, MELD-GRAIL-Na was found to be a better and more useful system for evaluating short-term (1- and 3-month) mortality in Korean patients with cirrhosis, especially those with advanced cirrhosis (CP class B and C).
13

Xu, Guodong, Peng Guo, Xuemei Li, and Yingying Jia. "Grey Relational Analysis and Its Application Based on the Angle Perspective in Time Series." Journal of Applied Mathematics 2014 (2014): 1–7. http://dx.doi.org/10.1155/2014/568697.

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The research scope of grey relational analysis has not been developed in recent years, and the exiting GRA models are all based on three perspectives, including distance perspective, slope perspective, and area perspective. Under this situation, a novel model called grey relational analysis based on angle perspective (GRAAP) was developed in this paper for the first time, and this model can expand the research scope of GRA. Like other GRA models, GRAAP not only has the properties of symmetry, uniqueness, comparability, and so forth but also can be used to make predictions, assessments, classifications, and so on. Finally, this novel model was proved to be rational and effective through a comparative study on the similar degree of four time series.
14

Trujillo Martínez, José Ramón. "«Ética caballeresca y cortesía en las traducciones artúricas»." Revista de Literatura Medieval 29 (December 21, 2018): 237–59. http://dx.doi.org/10.37536/rpm.2017.29.0.69404.

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Resumen: Además de entretenimiento, la materia artúrica hispánica es un vehículo de contenidos ideológicos y religiosos, y un instrumento privilegiado de instrucción moral de la nobleza. Este trabajo define y analiza algunas dimensiones relevantes de la ética caballeresca que propone el ciclo en prosa como modelo cortesano, centrando la atención en dos escenarios preferentes de la cortesía –el combate y el consejo del soberano– como reguladora de la acción militar y del poder real. Desde el punto de vista narratológico, la cortesía en el combate define la nobleza y valor de los personajes, y provoca nuevas líneas de acción. Un espíritu deportivo cortés y unas normas codificadas restringen la violencia empleada en el afán de proeza. El consejo muestra el derecho de los ricoshombres de la corte a ofrecer orientación al rey, avalados por los lazos del linaje y del vasallaje, lo que supone una restricción efectiva del poder soberano en los asuntos que afectan al reino.Palabras clave: Literatura artúrica, Santo Grial, Cortesía, Ética, Motivos caballerescos, Torneo.Abstract: Besides entertainment, the Hispanic Arthurian literature is a vehicle of ideological and religious contents, and a privileged instrument of moral instruction of the nobility. This work defines and analyzes some relevant dimensions of the chivalrous ethics in the cycle in prose as a model of Courtesy, centring the attention on two preferential scenes –the combat, and the council of the sovereign– focused on regulating the military action and the king’s power. From the point of narratologic view, the Courtesy in the combat defines the nobility and the value of the characters, and causes new lines of action. The desire of prowess is limited by the sportsmanship and a few of regulated limits. The Council shows the right of the nobles of the king’s household to provide guidance to the king, supported by the lineage links and of the vassalage, which means an effective restriction of the sovereign power in the kingdom matters.Keywords: Arthurian Literature, Holy Grail, Courtesy, Ethics, Motifs of Chivalry, Tournament.
15

Wirnsberger, Harald, Sandro Krauss, and Torsten Mayer-Gürr. "First independent Graz Lunar Gravity Model derived from GRAIL." Icarus 317 (January 2019): 324–36. http://dx.doi.org/10.1016/j.icarus.2018.08.011.

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16

Huo, Jinghai, Rubal Dua, and Prateek Bansal. "Inverse product differentiation logit model: Holy grail or not?" Energy Economics 131 (March 2024): 107379. http://dx.doi.org/10.1016/j.eneco.2024.107379.

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Xu, Guodong, Peng Guo, Xuemei Li, and Yingying Jia. "A Novel Method for the Comprehensive Evaluation of Aerospace Components Based on GRAAP." Mathematical Problems in Engineering 2015 (2015): 1–8. http://dx.doi.org/10.1155/2015/830606.

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The effective evaluation of aerospace components can strongly guarantee the normal running of spacecraft. A novel model called Grey Relational Analysis Based on the Angle Perspective (GRAAP) has been developed in this paper, which can be used to carry out evaluation for the aerospace components by comparing their relation intensities between evaluation component and reference components. Take a regular component as an example; a case study has been introduced based on GRAAP, and the results indicated that the grade of component waiting for evaluation was III, and it can be used in the low orbit spacecraft at least, such as the near earth satellite, and the results were also considered to be more objective than that from some other comprehensive methods. In addition, like other traditional GRA models, GRAAP not only can deal with the evaluation issues, but can also be used to make predictions, make classifications, and so on.
18

Miao, Shu Jiang, and Da Fang Fu. "Case Study of Nanjing Inner Ring on Air Pollution Dispersion from Roadway Tunnel Portals." Advanced Materials Research 610-613 (December 2012): 1895–900. http://dx.doi.org/10.4028/www.scientific.net/amr.610-613.1895.

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The tunnel module of a rather simple Lagrangian model GRAL (Grazer Langrange model) has been chosen to study air pollutant dispersion around tunnel portals in Nanjing inner ring. Two points have been made to popularize GRAL3.5TM (the tunnel module of a Lagrangian model GRAL; the update was in May 2003) and assure it more suitable for the actual situations in Nanjing. One is to derive a piecewise function of the intermediate parameter ‘stiffness’. Another is to take Romberg NOx-NO2 scheme into account. After these 2 works on GRAL3.5TM, NO2 dispersion from portals of all the 6 tunnels in Nanjing inner ring has been simulated. The importance of limiting urban traffic volume to control air quality around tunnel portals and roadways has been emphasized.
19

Liang, Ke, Lingyuan Meng, Sihang Zhou, Wenxuan Tu, Siwei Wang, Yue Liu, Meng Liu, Long Zhao, Xiangjun Dong, and Xinwang Liu. "MINES: Message Intercommunication for Inductive Relation Reasoning over Neighbor-Enhanced Subgraphs." Proceedings of the AAAI Conference on Artificial Intelligence 38, no. 9 (March 24, 2024): 10645–53. http://dx.doi.org/10.1609/aaai.v38i9.28935.

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GraIL and its variants have shown their promising capacities for inductive relation reasoning on knowledge graphs. However, the uni-directional message-passing mechanism hinders such models from exploiting hidden mutual relations between entities in directed graphs. Besides, the enclosing subgraph extraction in most GraIL-based models restricts the model from extracting enough discriminative information for reasoning. Consequently, the expressive ability of these models is limited. To address the problems, we propose a novel GraIL-based framework, termed MINES, by introducing a Message Intercommunication mechanism on the Neighbor-Enhanced Subgraph. Concretely, the message intercommunication mechanism is designed to capture the omitted hidden mutual information. It introduces bi-directed information interactions between connected entities by inserting an undirected/bi-directed GCN layer between uni-directed RGCN layers. Moreover, inspired by the success of involving more neighbors in other graph-based tasks, we extend the neighborhood area beyond the enclosing subgraph to enhance the information collection for inductive relation reasoning. Extensive experiments prove the promising capacity of the proposed MINES from various aspects, especially for the superiority, effectiveness, and transfer ability.
20

Yan, Jianguo, Luyuan Xu, Fei Li, Koji Matsumoto, J. Alexis P. Rodriguez, Hideaki Miyamoto, and James M. Dohm. "Lunar core structure investigation: Implication of GRAIL gravity field model." Advances in Space Research 55, no. 6 (March 2015): 1721–27. http://dx.doi.org/10.1016/j.asr.2014.12.038.

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21

Lemoine, Frank G., Sander Goossens, Terence J. Sabaka, Joseph B. Nicholas, Erwan Mazarico, David D. Rowlands, Bryant D. Loomis, et al. "High‒degree gravity models from GRAIL primary mission data." Journal of Geophysical Research: Planets 118, no. 8 (August 2013): 1676–98. http://dx.doi.org/10.1002/jgre.20118.

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22

Fatkhurrahman, Januar Arif, Ikha Rasti Julia Sari, and Yose Andriani. "Air Pollution Dispersion Modelling using GRAL in Area Near Coal-Steam Power Plant at Central Java." Jurnal Riset Teknologi Pencegahan Pencemaran Industri 12, no. 2 (December 10, 2021): 15–24. http://dx.doi.org/10.21771/jrtppi.2021.v12.no2.p15-24.

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Sulfur dioxide and Nitrogen dioxide were significant emissions emitted from coal-steam power plants that may cause health problems for humans and damage the environment. Studying the SO2 and NO2 gradients in Indonesian residential communities is critical for evaluating resident's SO2 and NO2 exposure. The method developed to assist analysis of spatial SO2 and NO2 gradients on a community scale combines a mesoscale Lagrangian dispersion model with field observations around coal-steam power plants using GRAL. The objectives of this study focused on GRAL dispersion of SO2 and NO2 in an Indonesian residential community near the coal-steam power plant, with a 6 km x 8 km resolution. Analysis of this model indicates a correlation between simulation and observation, with SO2 coefficient correlation (R) within 0.5 – 0.82 and NO2 coefficient correlation (R) within 0.30 – 0.59. Model performances analyze by NMSE and FB. The SO2 model is comparable to observation data since it has a better average NMSE and FB than the NO2 model. Due to data limitation of observation collected by grab sampling instead of continuous ambient measurement system affect different respond time compared with hourly data from the model.
23

Лычева, Irina Lycheva, Молчанова, and Vera Molchanova. "IMPROVING CONSUMER LENDING MODEL CLIENTS." Bulletin of Belgorod State Technological University named after. V. G. Shukhov 2, no. 1 (December 8, 2016): 245–49. http://dx.doi.org/10.12737/23353.

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The dynamism of the ongoing reforms in the domestic banking sector, one way or another, concerns the relationship of banks with their clients. The customer base responds differently to the reform of the banking system: there is a category of clients who do not take the action of the Central Bank of the Russian Federation, they argue that the monopoly of state-owned banks will lead to a deterioration of service, reduction in quality of banking products and riskiness of banking operations. But there is another category of customers who are positive about the changes and consider increasing the state presence in the banking market of the natural course of development. They link these changes with the possibility of increasing the funding the most important sectors of the real sector of the economy: construction, metallurgy, mechanical engineering. The problem of the banking sector today and in previous periods is similar in many respects: banks still continue to search for the elusive Holy Grail - lasting relationships with customers. Despite the high technology, graphical user interfaces and marketing strategy for the implementation of the task is still unclear in many respects.
24

Gracia, Paloma. "Los Baladros de Burgos (1498) y Sevilla (1535) frente a frente: su idiosincrasia y la de su modelo." Revista de Filología Española 102, no. 1 (July 7, 2022): 111–32. http://dx.doi.org/10.3989/rfe.2022.005.

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El artículo confronta las dos versiones impresas de Merlin —el Baladro del sabio Merlín con sus profecías impreso por Juan de Burgos (Burgos, 1498) y el “Baladro” publicado como primer libro de la Demanda del Sancto Grial con los maravillosos fechos de Lanzarote y de Galaz su hijo (Sevilla, 1535)— con su modelo francés: La Suite du Roman de Merlin, al objeto de discurrir sobre la naturaleza de los impresos.
25

Miao, Shu Jiang, and Da Fang Fu. "Introduction of NO-NO2-O3 Recycle into Model for Air Pollutant Dispersion from Tunnel Portals." Applied Mechanics and Materials 238 (November 2012): 791–94. http://dx.doi.org/10.4028/www.scientific.net/amm.238.791.

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NO-NO2-O3 recycle has been added into model dealing with air pollutant dispersion from tunnel portals-GRAL35TM to improve its performance. A mixed method GRAL-C has been discussed. It has been integrated into GRAL35TM to model dispersion in the street canyon where Tongjimen tunnel northern portal locates. It has been illustrated that GRAL35TM+C simulated NO2 dispersion more precisely than the original GRAL35TM. It requires background O3 concentrations.
26

Boiarchuk, Olena. "EXPERIMENTAL MODEL OF DIC SYNDROME." Grail of Science, no. 38 (April 18, 2024): 138–41. http://dx.doi.org/10.36074/grail-of-science.12.04.2024.021.

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Experiments were performed on 30 rabbits. DIC-syndrome was modeled with the drug "Efa-2", made on the basis of the poison of the multi-scaled snake Efa. The obtained experimental model corresponds to the subacute form of the course of DIC-syndrome, which lasts an average of 19 days and in which four stages of the development of the latter can be clearly traced. At the same time, changes developed in the internal organs of the experimental animals, which make it possible to state a violation of microcirculation, which is typical for DIC syndrome.
27

Goossens, Pierre L. "Animal models of human anthrax: The Quest for the Holy Grail." Molecular Aspects of Medicine 30, no. 6 (December 2009): 467–80. http://dx.doi.org/10.1016/j.mam.2009.07.005.

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Ameye, Laurent G., and Marian F. Young. "Animal models of osteoarthritis: lessons learned while seeking the ‘Holy Grail’." Current Opinion in Rheumatology 18, no. 5 (September 2006): 537–47. http://dx.doi.org/10.1097/01.bor.0000240369.39713.af.

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Baram, Tallie Z. "Models for infantile spasms: An arduous journey to the holy grail…" Annals of Neurology 61, no. 2 (February 2007): 89–91. http://dx.doi.org/10.1002/ana.21075.

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Antina, Rila Rindi. "Ekstrak Etanol Moringa Oleifera Lam Terhadap Folikulogenesis Pada Mencit Model Endometriosis." Jurnal Biosains Pascasarjana 19, no. 3 (December 25, 2017): 246. http://dx.doi.org/10.20473/jbp.v19i3.2017.246-259.

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Endometriosis didefinisikan sebagai adanya jaringan endometrium di luar rahim.Peningkatan konsentrasi sitokin inflamasi dan faktor pertumbuhan di dalam cairanperitonium berkontribusi pada pembentukan lesi peritonium. Faktor pertumbuhanberperan selama folliculogenesis. Moringa oleifera kaya akan flavonoid. Kuercetin dankaempferol adalah flavonoid, senyawa dengan gugus hidroksil fenolik dengan aksiantioksidan yang memiliki kegunaan potensial terapeutik. Penelitian ini untukmembuktikan adanya pengaruh pemberian ekstrak etanol daun kelor (Moringa oleiferaLam) terhadap folikulogenesis pada mencit (Mus musculus) model endometriosis.Metode penelitian menggunakan mencit (Mus musculus) 20-25g yang dibagi menjadi duakelompok, yaitu kelompok kontrol endometriosis dan kelompok perlakuan diberi ekstraketanol daun kelor 0,35 mg/gBB selama 14 hari. Jaringan ovarium dilakukan pemeriksaanhistopatologi dengan pengecatan hematoxylin-eosin. Hasil penelitian menunjukkanterdapat perbedaan yang signifikan (ρ<0,05) jumlah folikel primer, jumlah folikelsekunder, jumlah folikel tersier, jumlah folikel de graaf pada kelompok kontrol dankelompok perlakuan. Kesimpulan Penelitian menunjukkan ekstrak etanol daun kelormeningkatkan folikulogenesis pada mencit model endometriosisKata kunci—Ekstrak etanol daun kelor, folikulogenesis, endometrosis
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Gonçalves, Jaqueline dos Santos, Suely Salgueiro Chacon, Fabiana Correia Bezerra, and Rebecca Isabelle Herculano Silva. "O “Decrescimento Econômico” através da Relocalização da Produção como Estratégia para um Desenvolvimento Regional." RPER, no. 35 (March 31, 2014): 29–37. http://dx.doi.org/10.59072/rper.vi35.414.

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O desenvolvimento econômico tem sido o “santo graal” da sociedade. Contudo, quando se revela difícil determinar a sua sustentabilidade, o questionamento desse desenvolvimento é inevitável. Logo, o interesse pela realização desse estudo deve-se ao processo de discussão sobre o desenvolvimento, cabendo neste momento refletir sobre uma nova consciência em prol da natureza e do próprio homem, com especial atenção ao conceito de decrescimento. Através de fontes bibliográficas foi possível analisá-lo como a mudança de paradigma econômico e revolução cultural necessária para a construção de uma nova sociedade, exigindo mudanças desde culturais até sociais para se rever o atual modelo de progresso. Assim, introduzir o decrescimento econômico através do parâmetro da relocalização da produção parece ser uma alternativa para essa mudança de paradigma no âmbito de um desenvolvimento regional duradouro.
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Chen, Zhaoxi, and Zidan Chen. "The Identification of Impact Craters from GRAIL-Acquired Gravity Data by U-Net Architecture." Remote Sensing 14, no. 12 (June 10, 2022): 2783. http://dx.doi.org/10.3390/rs14122783.

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The identification of impact craters on the Moon and other planetary bodies is of great significance to studying and constraining the dynamical process and evolution of the Solar System. Traditionally, this has been performed through the visual examination of images. Due to the effect of overburden, some structural features cannot be effectively identified from optical images, resulting in limitations in the scope, efficiency and accuracy of identification. In this paper, we investigate the viability of convolutional neural networks (CNNs) to perform the detection of impact craters from GRAIL-acquired gravity data. The ideal values of each hyperparameter in U-net architecture are determined after dozens of iterations of model training, testing and evaluation. The final model was evaluated by the Loss function with the low value of 0.04, indicating that the predicted output of the model reached a relatively high fitting degree with the prior labelled output. The comparative results with different methods show that the proposed method has a clear detection of the target features, with an accuracy of more than 80%. In addition, the detection results of the whole image account for 83% of the number of manually delineated gravity anomalies. The proposed method can still achieve the same quality for the identification of the gravity anomalies caused by impact craters under the condition that the resolution of GRAIL gravity data are not superior. Our results demonstrate that the U-net architecture can be a very effective tool for the rapid and automatic identification of impact craters from gravity map on the Moon, as well as other Solar System bodies.
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Watt, Douglas F. "Affirmative-action for the brainstem in the neuroscience of consciousness: The zeitgeist of the brainstem as a “dumb arousal” system." Behavioral and Brain Sciences 30, no. 1 (February 2007): 108–10. http://dx.doi.org/10.1017/s0140525x07001161.

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Merker offers a remarkable statement about the neural integration essential to conscious states provided by the mesodiencephalon. The model for triangular interaction between action selection, target selection, and emotion is heuristic. Unfortunately, there is little interest (relatively speaking) in neuroscience in the mesodiencephalon, and attention is currently heavily directed to the telencephalon. This suggests that there may be less real momentum than commonly assumed towards the Holy Grail of neuroscience, a scientific theory of mind, despite the major upsurge in interest.
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Lemoine, Frank G., Sander Goossens, Terence J. Sabaka, Joseph B. Nicholas, Erwan Mazarico, David D. Rowlands, Bryant D. Loomis, et al. "GRGM900C: A degree 900 lunar gravity model from GRAIL primary and extended mission data." Geophysical Research Letters 41, no. 10 (May 28, 2014): 3382–89. http://dx.doi.org/10.1002/2014gl060027.

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Stafstrom, Carl E. "Animal Models of Infantile Spasms: Is the Holy Grail Finally in Sight?" Epilepsy Currents 8, no. 5 (September 2008): 131–33. http://dx.doi.org/10.1111/j.1535-7511.2008.00267.x.

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Petrov, Anton, Emilia Georgieva, and Elena Hristova. "Sensitivity Analysis of Modelled Air Pollutant Distribution around Buildings under Different Meteorological Conditions." Atmosphere 15, no. 6 (May 25, 2024): 638. http://dx.doi.org/10.3390/atmos15060638.

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The distribution of air pollutants in urban areas is significantly influenced by the presence of various geometric structures, including buildings, bridges, and tunnels. In built-up environments, meteorological conditions may influence the accumulation or dispersion of air pollutants in specific zones. This study examines the impact of wind and atmospheric stability on the dispersion of air pollutants around an apartment building situated in close proximity to a busy boulevard in a residential district of Sofia, Bulgaria. A series of dispersion simulations were conducted using the Graz Lagrangian Model (GRAL v.22.09) for a range of meteorological conditions, defined as combinations of the direction and velocity of the approaching flow, and of stability conditions within the study area of 1 × 1 km, with a horizontal resolution of 2 m. The resulting spatial distribution revealed the presence of hotspots and strong gradients in the concentration field. A simulation with meteorological data was also conducted, which was aligned with a campaign to monitor vehicular traffic. The sensitivity tests indicate that GRAL is capable of reproducing high-resolution pollutant fields, accounting for building effects at relatively low computational costs. This makes the model potentially attractive for city-wide simulations as well as for air pollution exposure estimation.
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何, 山. "Research on Production Decision Model of Automobile Enterprises under Double Inte-gral Policy." World Economic Research 11, no. 03 (2022): 205–13. http://dx.doi.org/10.12677/wer.2022.113023.

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Banu, Ionut, Ioana Stoica, Gheorghe Bumbac, and Grigore Bozga. "Modeling of the Unsteady State Methanol Synthesis at the Level of Catalyst Pellet." Revista de Chimie 68, no. 6 (July 15, 2017): 1153–58. http://dx.doi.org/10.37358/rc.17.6.5632.

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In a fixed bed of porous catalyst pellets, there are developed two composition and temperature fields, one in the fluid phase and the other one at the level of solid pellets. The objective of this work is to evaluate, by numerical simulation, the unsteady state behavior of a catalyst pellet in typical operating conditions for methanol synthesis reactors. The process kinetics was described by the model published by Graaf et al (1990) and the reaction-diffusion process inside the pellet is based on the Wilke-Bosanquet model. The results showed a short composition and temperature stabilization time, generally below 4 seconds, for a spherical catalyst pellet having typical dimensions for industrial applications.
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Samar, Hanna. "EXACTLY SOLVABLE MODEL OF TOPOLOGICAL TRANSITIONS IN METALS." ГРААЛЬ НАУКИ, no. 6 (July 4, 2021): 196–202. http://dx.doi.org/10.36074/grail-of-science.25.06.2021.033.

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In this paper, we consider ETP using a precisely solvable model of an electron in a crystal. The main characteristics of the transition are given by analytical functions that contain only the parameters of the potential. The results of calculations are compared with experimental data on the Lifshitz phase transition (genus transition) in normal metals. The practical significance of the work is to increase the accuracy of quantitative predictions of the physical properties of alloys of various transition metals.
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Khanmamedova, E. "MATHEMATICAL MODEL ANALYSIS OF GRAPHENE OXIDE THERMAL DEVELOPMENT." Grail of Science, no. 26 (April 24, 2023): 283–85. http://dx.doi.org/10.36074/grail-of-science.14.04.2023.050.

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The thermal processing mathematical model of graphene oxide is a model that mathematically describes the changes that the material undergoes during thermal processing. This model takes into account the changes in the crystal structure of the material during thermal treatment and the effects of these changes on the properties of the material.
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Nance, Tracy, Timothy Shaver, Yifan Zhou, Margaret Antonio, Yinjie Gao, Jonathan Heiss, Robert Calef, et al. "Abstract 7566: Identification of cancer subtypes with a ctDNA-based targeted methylation assay." Cancer Research 84, no. 6_Supplement (March 22, 2024): 7566. http://dx.doi.org/10.1158/1538-7445.am2024-7566.

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Abstract Introduction: Identifying cancer subtypes is necessary for cancer diagnosis, prognosis determination, and treatment selection. Furthermore, as transformation between subtypes is increasingly recognized as a key resistance mechanism to targeted therapies, serial subtype reassessment is likely to gain adoption. Cancer subtypes have traditionally been determined by pathologists based on histology; more recently, molecular subtyping has been performed using IHC, RNAseq, or assays that detect genetic alterations. However, these methods have significant limitations, including tissue biopsy requirement (IHC and RNAseq), low discriminative resolution for distinct transcriptional programs (IHC and mutation detection), and poor reproducibility and feasibility (RNAseq). The GRAIL plasma-only, ctDNA-based targeted methylation platform is a robust, biopsy-free, scalable assay that can distinguish cancer methylation patterns between different cancer signal origins through the use of a proprietary classifier. Here, we explore the GRAIL platform’s potential to detect finer-scale differences in cancer biology by developing classification algorithms for subtyping of three common cancer types. Methods: As part of the Circulating Cell-free Genome Atlas (NCT02889978) and STRIVE (NCT03085888) studies, clinical data were recorded and plasma samples were collected, accessioned, stored, and processed through GRAIL’s targeted methylation assay from 3,989 cancer and 6,013 non-cancer participants. We developed algorithms to predict cancer status and subtype for breast (triple negative breast cancer [TNBC] model; 531 cancer training participants), lung (lung histology model; 334 cancer training participants), and head and neck (HPV model; 3090 cancer training participants) cancers. Dimensionality reduction of methylation data was performed to illustrate subtype separation within these cancer types. Performance of these three algorithms was assessed on a held-out cohort of cancer samples (184 breast, 241 lung, 67 head and neck) with detectable ctDNA. Results: The lung histology model correctly classified 95% (105/111) of adenocarcinomas, 88% (68/77) of squamous cell carcinomas, and 94% (59/63) of lung neuroendocrine carcinomas and tumors. The TNBC model correctly classified 84% (58/69) of TNBCs and 82% (94/115) of non-TNBCs. The HPV model correctly identified 98% (48/49) of HPV-positive head and neck cancers, and 89% (16/18) of HPV-negative head and neck cancers. Conclusions: GRAIL’s proprietary ctDNA-based targeted methylation platform demonstrates the ability to accurately predict cancer subtypes in multiple cancers using only a plasma sample without the need for tumor biopsy. Future efforts will be directed towards generalizing the GRAIL subtyping method to additional cohorts and cancer types. Citation Format: Tracy Nance, Timothy Shaver, Yifan Zhou, Margaret Antonio, Yinjie Gao, Jonathan Heiss, Robert Calef, Joseph Hiatt, Oliver Venn, Joerg Bredno, John Beausang, Lisa Newman, Charles Swanton, Chun Zhang. Identification of cancer subtypes with a ctDNA-based targeted methylation assay [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 7566.
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Krone-Martins, A., L. Delchambre, O. Wertz, C. Ducourant, F. Mignard, R. Teixeira, J. Klüter, et al. "Gaia GraL: Gaia DR2 gravitational lens systems." Astronomy & Astrophysics 616 (August 2018): L11. http://dx.doi.org/10.1051/0004-6361/201833337.

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Context. Multiply imaged gravitationally lensed quasars are among the most interesting and useful observable extragalactic phenomena. Because their study constitutes a unique tool in various fields of astronomy, they are highly sought, but difficult to find. Even in this era of all-sky surveys, discovering them remains a great challenge, with barely a few hundred systems currently known. Aims. We aim to discover new multiply imaged quasar candidates in the recently published Gaia Data Release 2 (DR2), which is the astrometric and photometric all-sky survey with the highest spatial resolution that achieves effective resolutions from 0.4″ to 2.2″. Methods. We cross-matched a merged list of quasars and candidates with Gaia DR2 and found 1 839 143 counterparts within 0.5″. We then searched matches with more than two Gaia DR2 counterparts within 6″. We further narrowed the resulting list using astrometry and photometry compatibility criteria between the Gaia DR2 counterparts. A supervised machine-learning method, called extremely randomized trees, was finally adopted to assign a probability of being lensed to each remaining system. Results. We report the discovery of two quadruply imaged quasar candidates that are fully detected in Gaia DR2. These are the most promising new quasar lens candidates from Gaia DR2 and a simple singular isothermal ellipsoid lens model is able to reproduce their image positions to within ~1 mas. This Letter demonstrates the discovery potential of Gaia for gravitational lenses.
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Saks, Alan M., and Robert R. Haccoun. "Is the “Third-Generation Model” New and Is It the Holy Grail of Adaptive Learning?" Industrial and Organizational Psychology 1, no. 4 (December 2008): 480–83. http://dx.doi.org/10.1111/j.1754-9434.2008.00090.x.

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44

DUAN, JianFeng, JianFeng CAO, Ming CHEN, and Yu ZHANG. "The improvements of Chang’E series satellites orbit determination from GRAIL lunar gravity model." SCIENTIA SINICA Physica, Mechanica & Astronomica 47, no. 6 (January 24, 2017): 069502. http://dx.doi.org/10.1360/sspma2016-00320.

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45

Sokolova, Halyna, and Inna Valchenko. "INTERCULTURAL MODEL OF FOREIGN LANGUAGE TEACHING: WAYS OF OPTIMIZATION." Grail of Science, no. 28 (June 23, 2023): 317–23. http://dx.doi.org/10.36074/grail-of-science.09.06.2023.50.

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The article is devoted to various issues of methods of teaching a foreign language to foreign students. The article notes the need to differentiate the level of basic education of foreign students and individual approach to each of them, thus during studying should use different groups of tasks, and pay attention on degree of students' lexical and grammatical material, their general "background" knowledge and emotional mood. This presented work analyzes the features of the linguistic-socio-cultural method; some principles of the functional-communicative approach are clarified; emphasizes the importance of using the "translation technique" in the classroom in English and Russian, as well as the use of a thematic glossary in the course "Country Studies. History"; the importance of reading literature in Russian and English in the process of social and cultural adaptation of foreign students of the preparatory department is studied. The purpose of the article is to demonstrate various methods and techniques for presenting new material, consolidating and testing knowledge that can be used by a teacher in practical classes in a foreign language. The task for the authors is to find effective forms of education and ways of optimization, to identify mechanisms for optimizing the educational process that can develop the intercultural competence of students, as well as contribute to a positive mood of students during their staying, living and studying in our country. The authors come to the conclusion that texts and tasks for learning should be cognitive, arouse interest among students and be quite complex; it is necessary to use different groups of tasks, a small number of exercises for one rule being studied, and also actively apply game situations, tasks for finding errors and working with dialogues. The selection of reading material, the use of fundamental methods in the study of a foreign language and their integration into a modern communicative method play the important role. Such work with students (as well as the “translation technique”) develops memory, thinking and logic, helps to create an English-speaking/Ukrainian-speaking environment, there by overcoming the psychological language barrier among students. The basic research methods are cultural-typological and contrastive-comparative.
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Rosenfeld, Michael E., Kevin G. S. Carson, Jason L. Johnson, Helen Williams, Christopher L. Jackson, and Stephen M. Schwartz. "Animal models of spontaneous plaque rupture: The holy grail of experimental atherosclerosis research." Current Atherosclerosis Reports 4, no. 3 (May 2002): 238–42. http://dx.doi.org/10.1007/s11883-002-0025-3.

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47

Ducourant, C., O. Wertz, A. Krone-Martins, R. Teixeira, J. F. Le Campion, L. Galluccio, J. Klüter, et al. "Gaia GraL: Gaia DR2 gravitational lens systems." Astronomy & Astrophysics 618 (October 2018): A56. http://dx.doi.org/10.1051/0004-6361/201833480.

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Context. Thanks to its spatial resolution, the ESA/Gaia space mission offers a unique opportunity to discover new multiply imaged quasars and to study the already known lensed systems at sub-milliarcsecond astrometric precisions. Aims. In this paper, we address the detection of the known multiply imaged quasars from the Gaia Data Release 2 (DR2) and determine the astrometric and photometric properties of the individually detected images found in the Gaia DR2 catalogue. Methods. We have compiled an exhaustive list of quasar gravitational lenses from the literature to search for counterparts in the Gaia DR2. We then analysed the astrometric and photometric properties of these Gaia’s detections. To highlight the tremendous potential of Gaia at the sub-milliarcsecond level we finally performed a simple Bayesian modelling of the well-known gravitational lens system HE0435-1223, using Gaia DR2 and HST astrometry. Results. From 481 known multiply imaged quasars, 206 have at least one image found in the Gaia DR2. Among the 44 known quadruply imaged quasars of the list, 29 have at least one image in the Gaia DR2, 12 of which are fully detected (2MASX J01471020+4630433, HE 0435-1223, SDSS1004+4112, PG1115+080, RXJ1131-1231, 2MASS J11344050-2103230, 2MASS J13102005-1714579, B1422+231, J1606-2333, J1721+8842, WFI2033-4723, WGD2038-4008), eight have three counterparts, eight have two and one has only one. As expected, the modelling of HE0435-1223 shows that the model parameters are significantly better constrained when using Gaia astrometry compared to HST astrometry, in particular the relative positions of the background quasar source and the centroid of the deflector. The Gaia sub-milliarcsecond astrometry also significantly reduces the parameter correlations. Conclusions. Besides providing an up-to-date list of multiply imaged quasars and their detection in the Gaia DR2, this paper shows that more complex modelling scenarios will certainly benefit from Gaia sub-milliarcsecond astrometry.
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Delchambre, L., A. Krone-Martins, O. Wertz, C. Ducourant, L. Galluccio, J. Klüter, F. Mignard, et al. "Gaia GraL: Gaia DR2 Gravitational Lens Systems." Astronomy & Astrophysics 622 (February 2019): A165. http://dx.doi.org/10.1051/0004-6361/201833802.

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Aims. In this work, we aim to provide a reliable list of gravitational lens candidates based on a search performed over the entire Gaia Data Release 2 (Gaia DR2). We also aim to show that the astrometric and photometric information coming from the Gaia satellite yield sufficient insights for supervised learning methods to automatically identify strong gravitational lens candidates with an efficiency that is comparable to methods based on image processing. Methods. We simulated 106 623 188 lens systems composed of more than two images, based on a regular grid of parameters characterizing a non-singular isothermal ellipsoid lens model in the presence of an external shear. These simulations are used as an input for training and testing our supervised learning models consisting of extremely randomized trees (ERTs). These trees are finally used to assign to each of the 2 129 659 clusters of celestial objects extracted from the Gaia DR2 a discriminant value that reflects the ability of our simulations to match the observed relative positions and fluxes from each cluster. Once complemented with additional constraints, these discriminant values allow us to identify strong gravitational lens candidates out of the list of clusters. Results. We report the discovery of 15 new quadruply-imaged lens candidates with angular separations of less than 6″ and assess the performance of our approach by recovering 12 of the 13 known quadruply-imaged systems with all their components detected in Gaia DR2 with a misclassification rate of fortuitous clusters of stars as lens systems that is below 1%. Similarly, the identification capability of our method regarding quadruply-imaged systems where three images are detected in Gaia DR2 is assessed by recovering 10 of the 13 known quadruply-imaged systems having one of their constituting images discarded. The associated misclassification rate varies between 5.83% and 20%, depending on the image we decided to remove.
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Fesenko, Galyna. "DEVELOPING THE VALUE-ORIENTED MANAGEMENT MODEL FOR CULTURAL HERITAGE REСOVER." Grail of Science, no. 29 (July 19, 2023): 409–17. http://dx.doi.org/10.36074/grail-of-science.07.07.2023.070.

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This study examines the ways how cultural heritage can be reconstracted from the effects of armed conflicts, in Ukraine and beyond (case of Warszawa). It includes a review of important the international law, architacturel and cultural frameworks.The Warsaw's experience in reconstruction is analyzed, which bold technological solutions were used in the reconstruction of cultural objects. This study provides a contextual background to assess how to create an efficient the Reconstruction Project Management Office.
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Li, An, and Zhang. "The Dynamic 3D Genome in Gametogenesis and Early Embryonic Development." Cells 8, no. 8 (July 29, 2019): 788. http://dx.doi.org/10.3390/cells8080788.

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During gametogenesis and early embryonic development, the chromatin architecture changes dramatically, and both the transcriptomic and epigenomic landscape are comprehensively reprogrammed. Understanding these processes is the holy grail in developmental biology and a key step towards evolution. The 3D conformation of chromatin plays a central role in the organization and function of nuclei. Recently, the dynamics of chromatin structures have been profiled in many model and non-model systems, from insects to mammals, resulting in an interesting comparison. In this review, we first introduce the research methods of 3D chromatin structure with low-input material suitable for embryonic study. Then, the dynamics of 3D chromatin architectures during gametogenesis and early embryonic development is summarized and compared between species. Finally, we discuss the possible mechanisms for triggering the formation of genome 3D conformation in early development.

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