Journal articles on the topic 'GPCR function and regulation'
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Liu, Nannan, Yifan Wang, Ting Li, and Xuechun Feng. "G-Protein Coupled Receptors (GPCRs): Signaling Pathways, Characterization, and Functions in Insect Physiology and Toxicology." International Journal of Molecular Sciences 22, no. 10 (May 17, 2021): 5260. http://dx.doi.org/10.3390/ijms22105260.
Full textMelhem, Hassan, Berna Kaya, C. Korcan Ayata, Petr Hruz, and Jan Hendrik Niess. "Metabolite-Sensing G Protein-Coupled Receptors Connect the Diet-Microbiota-Metabolites Axis to Inflammatory Bowel Disease." Cells 8, no. 5 (May 14, 2019): 450. http://dx.doi.org/10.3390/cells8050450.
Full textChaudhary, Preeti Kumari, Sanggu Kim, Youngheun Jee, Seung-Hun Lee, Kyung-Mee Park, and Soochong Kim. "Role of GRK6 in the Regulation of Platelet Activation through Selective G Protein-Coupled Receptor (GPCR) Desensitization." International Journal of Molecular Sciences 21, no. 11 (May 30, 2020): 3932. http://dx.doi.org/10.3390/ijms21113932.
Full textChini, B., and M. Parenti. "G-protein coupled receptors in lipid rafts and caveolae: how, when and why do they go there?" Journal of Molecular Endocrinology 32, no. 2 (April 1, 2004): 325–38. http://dx.doi.org/10.1677/jme.0.0320325.
Full textWalther, Cornelia, and Stephen S. G. Ferguson. "Minireview: Role of Intracellular Scaffolding Proteins in the Regulation of Endocrine G Protein-Coupled Receptor Signaling." Molecular Endocrinology 29, no. 6 (June 1, 2015): 814–30. http://dx.doi.org/10.1210/me.2015-1091.
Full textCottrell, GS. "Roles of proteolysis in regulation of GPCR function." British Journal of Pharmacology 168, no. 3 (January 16, 2013): 576–90. http://dx.doi.org/10.1111/j.1476-5381.2012.02234.x.
Full textN'Diaye, Elsa-Noah, Aylin C. Hanyaloglu, Kimberly K. Kajihara, Manojkumar A. Puthenveedu, Ping Wu, Mark von Zastrow, and Eric J. Brown. "The Ubiquitin-like Protein PLIC-2 Is a Negative Regulator of G Protein-coupled Receptor Endocytosis." Molecular Biology of the Cell 19, no. 3 (March 2008): 1252–60. http://dx.doi.org/10.1091/mbc.e07-08-0775.
Full textCaballero, Adriana, Sarah A. Mahn, Mudassir S. Ali, M. Rose Rogers, and Adriano Marchese. "Heterologous regulation of CXCR4 lysosomal trafficking." Journal of Biological Chemistry 294, no. 20 (April 1, 2019): 8023–36. http://dx.doi.org/10.1074/jbc.ra118.005991.
Full textPoll, Brian G., Lihe Chen, Chung-Lin Chou, Viswanathan Raghuram, and Mark A. Knepper. "Landscape of GPCR expression along the mouse nephron." American Journal of Physiology-Renal Physiology 321, no. 1 (July 1, 2021): F50—F68. http://dx.doi.org/10.1152/ajprenal.00077.2021.
Full textLuo, Jiaqian, and Fa-Xing Yu. "GPCR-Hippo Signaling in Cancer." Cells 8, no. 5 (May 8, 2019): 426. http://dx.doi.org/10.3390/cells8050426.
Full textCarrington, Sheridan J., Ciria C. Hernandez, Daniel R. Swale, Oluwatosin A. Aluko, Jerod S. Denton, and Roger D. Cone. "G protein–coupled receptors differentially regulate glycosylation and activity of the inwardly rectifying potassium channel Kir7.1." Journal of Biological Chemistry 293, no. 46 (September 26, 2018): 17739–53. http://dx.doi.org/10.1074/jbc.ra118.003238.
Full textJiang, Yuhong, Xin Zhuo, and Canquan Mao. "G Protein-coupled Receptors in Cancer Stem Cells." Current Pharmaceutical Design 26, no. 17 (June 7, 2020): 1952–63. http://dx.doi.org/10.2174/1381612826666200305130009.
Full textWang, Jialu, Clarice Gareri, and Howard A. Rockman. "G-Protein–Coupled Receptors in Heart Disease." Circulation Research 123, no. 6 (August 31, 2018): 716–35. http://dx.doi.org/10.1161/circresaha.118.311403.
Full textBerndt, Sandra, and Ines Liebscher. "New Structural Perspectives in G Protein-Coupled Receptor-Mediated Src Family Kinase Activation." International Journal of Molecular Sciences 22, no. 12 (June 17, 2021): 6489. http://dx.doi.org/10.3390/ijms22126489.
Full textWright, Shane C., Maria Consuelo Alonso Cañizal, Tobias Benkel, Katharina Simon, Christian Le Gouill, Pierre Matricon, Yoon Namkung, et al. "FZD5 is a Gαq-coupled receptor that exhibits the functional hallmarks of prototypical GPCRs." Science Signaling 11, no. 559 (December 4, 2018): eaar5536. http://dx.doi.org/10.1126/scisignal.aar5536.
Full textDrynda, Robert, Shanta J. Persaud, James E. Bowe, and Peter M. Jones. "The Placental Secretome: Identifying Potential Cross-Talk Between Placenta and Islet β-Cells." Cellular Physiology and Biochemistry 45, no. 3 (2018): 1165–71. http://dx.doi.org/10.1159/000487357.
Full textMilligan, Graeme, Trond Ulven, Hannah Murdoch, and Brian D. Hudson. "G-protein-coupled receptors for free fatty acids: nutritional and therapeutic targets." British Journal of Nutrition 111, S1 (January 2, 2014): S3—S7. http://dx.doi.org/10.1017/s0007114513002249.
Full textZaidman, Nathan A., Viktor N. Tomilin, Naghmeh Hassanzadeh Khayyat, Mahendra Damarla, Josephine Tidmore, Diane E. Capen, Dennis Brown, Oleh M. Pochynyuk, and Jennifer L. Pluznick. "Adhesion-GPCR Gpr116 (ADGRF5) expression inhibits renal acid secretion." Proceedings of the National Academy of Sciences 117, no. 42 (October 1, 2020): 26470–81. http://dx.doi.org/10.1073/pnas.2007620117.
Full textCarbone, Simona E., Nicholas A. Veldhuis, Arisbel B. Gondin, and Daniel P. Poole. "G protein-coupled receptor trafficking and signaling: new insights into the enteric nervous system." American Journal of Physiology-Gastrointestinal and Liver Physiology 316, no. 4 (April 1, 2019): G446—G452. http://dx.doi.org/10.1152/ajpgi.00406.2018.
Full textLi, Ting, and Nannan Liu. "Role of the G-Protein-Coupled Receptor Signaling Pathway in Insecticide Resistance." International Journal of Molecular Sciences 20, no. 17 (September 3, 2019): 4300. http://dx.doi.org/10.3390/ijms20174300.
Full textZhang, Quanfeng, Bing Liu, Yinglin Li, Lili Yin, Muhammad Younus, Xiaohan Jiang, Zhaohan Lin, et al. "Regulating quantal size of neurotransmitter release through a GPCR voltage sensor." Proceedings of the National Academy of Sciences 117, no. 43 (October 12, 2020): 26985–95. http://dx.doi.org/10.1073/pnas.2005274117.
Full textDores, Michael R., Huilan Lin, Neil J. Grimsey, Francisco Mendez, and JoAnn Trejo. "The α-arrestin ARRDC3 mediates ALIX ubiquitination and G protein–coupled receptor lysosomal sorting." Molecular Biology of the Cell 26, no. 25 (December 15, 2015): 4660–73. http://dx.doi.org/10.1091/mbc.e15-05-0284.
Full textvon Zastrow, M. "Role of endocytosis in signalling and regulation of G-protein-coupled receptors." Biochemical Society Transactions 29, no. 4 (August 1, 2001): 500–504. http://dx.doi.org/10.1042/bst0290500.
Full textShpakov, A. O., and E. A. Shpakova. "Prospects for use of peptides and their derivatives, structurally corresponding to the G protein-coupled receptors, in medicine." Biomeditsinskaya Khimiya 61, no. 1 (January 2015): 19–29. http://dx.doi.org/10.18097/pbmc20156101019.
Full textMatúš, Daniel, and Simone Prömel. "G Proteins and GPCRs in C. elegans Development: A Story of Mutual Infidelity." Journal of Developmental Biology 6, no. 4 (November 25, 2018): 28. http://dx.doi.org/10.3390/jdb6040028.
Full textMarivin, Arthur, Veronika Morozova, Isha Walawalkar, Anthony Leyme, Dmitry A. Kretov, Daniel Cifuentes, Isabel Dominguez, and Mikel Garcia-Marcos. "GPCR-independent activation of G proteins promotes apical cell constriction in vivo." Journal of Cell Biology 218, no. 5 (April 4, 2019): 1743–63. http://dx.doi.org/10.1083/jcb.201811174.
Full textChaudhary, Preeti Kumari, and Soochong Kim. "The GRKs Reactome: Role in Cell Biology and Pathology." International Journal of Molecular Sciences 22, no. 7 (March 25, 2021): 3375. http://dx.doi.org/10.3390/ijms22073375.
Full textPal, Kasturi, Sun-hee Hwang, Bandarigoda Somatilaka, Hemant Badgandi, Peter K. Jackson, Kathryn DeFea, and Saikat Mukhopadhyay. "Smoothened determines β-arrestin–mediated removal of the G protein–coupled receptor Gpr161 from the primary cilium." Journal of Cell Biology 212, no. 7 (March 21, 2016): 861–75. http://dx.doi.org/10.1083/jcb.201506132.
Full textWERRY, Tim D., Graeme F. WILKINSON, and Gary B. WILLARS. "Mechanisms of cross-talk between G-protein-coupled receptors resulting in enhanced release of intracellular Ca2+." Biochemical Journal 374, no. 2 (September 1, 2003): 281–96. http://dx.doi.org/10.1042/bj20030312.
Full textPrajapati, Subhash C., Ratnakar Singh, and Shyam S. Chauhan. "Human dipeptidyl peptidase III regulates G-protein coupled receptor-dependent Ca2+ concentration in human embryonic kidney 293T cells." Biological Chemistry 397, no. 6 (June 1, 2016): 563–69. http://dx.doi.org/10.1515/hsz-2016-0117.
Full textHalls, Michelle L. "Constitutive formation of an RXFP1-signalosome: a novel paradigm in GPCR function and regulation." British Journal of Pharmacology 165, no. 6 (February 22, 2012): 1644–58. http://dx.doi.org/10.1111/j.1476-5381.2011.01470.x.
Full textPera, Tonio, Eric Tompkins, Michael Katz, Bin Wang, Deepak A. Deshpande, Edward J. Weinman, and Raymond B. Penn. "Specificity of NHERF1 regulation of GPCR signaling and function in human airway smooth muscle." FASEB Journal 33, no. 8 (May 2019): 9008–16. http://dx.doi.org/10.1096/fj.201900323r.
Full textZhu, Tang, Fernand Gobeil, Alejandro Vazquez-Tello, Martin Leduc, Lenka Rihakova, Michela Bossolasco, Ghassan Bkaily, et al. "Intracrine signaling through lipid mediators and their cognate nuclear G-protein-coupled receptors: a paradigm based on PGE2, PAF, and LPA1 receptorsThis paper is one of a selection of papers published in this Special Issue, entitled The Nucleus: A Cell Within A Cell." Canadian Journal of Physiology and Pharmacology 84, no. 3-4 (March 2006): 377–91. http://dx.doi.org/10.1139/y05-147.
Full textMarzano, Federica, Antonio Rapacciuolo, Nicola Ferrara, Giuseppe Rengo, Walter J. Koch, and Alessandro Cannavo. "Targeting GRK5 for Treating Chronic Degenerative Diseases." International Journal of Molecular Sciences 22, no. 4 (February 15, 2021): 1920. http://dx.doi.org/10.3390/ijms22041920.
Full textMaggio, Roberto, Irene Fasciani, Mario Rossi, Jacopo Di Gregorio, Ilaria Pietrantoni, Valentina Puca, Vincenzo Flati, and Marco Scarselli. "Variants of G protein-coupled receptors: a reappraisal of their role in receptor regulation." Biochemical Society Transactions 44, no. 2 (April 11, 2016): 589–94. http://dx.doi.org/10.1042/bst20150239.
Full textBerbari, Nicolas F., Andrew D. Johnson, Jacqueline S. Lewis, Candice C. Askwith, and Kirk Mykytyn. "Identification of Ciliary Localization Sequences within the Third Intracellular Loop of G Protein-coupled Receptors." Molecular Biology of the Cell 19, no. 4 (April 2008): 1540–47. http://dx.doi.org/10.1091/mbc.e07-09-0942.
Full textSchiedel, Anke C., Meryem Kose, Carlos Barreto, Beatriz Bueschbell, Giulia Morra, Ozge Sensoy, and Irina S. Moreira. "Prediction and Targeting of Interaction Interfaces in G-protein Coupled Receptor Oligomers." Current Topics in Medicinal Chemistry 18, no. 8 (July 18, 2018): 714–46. http://dx.doi.org/10.2174/1568026618666180604082610.
Full textHollander-Cohen, Lian, Matan Golan, and Berta Levavi-Sivan. "Transcriptome of Distinct LH and FSH Cells Reveals Different Regulation Unique to Each Cell Type." Journal of the Endocrine Society 5, Supplement_1 (May 1, 2021): A557. http://dx.doi.org/10.1210/jendso/bvab048.1136.
Full textJiang, Yuhui, Xiaoduo Xie, Yixuan Zhang, Xiaolin Luo, Xiao Wang, Fengjuan Fan, Dawei Zheng, Zhenzhen Wang, and Yan Chen. "Regulation of G-Protein Signaling by RKTG via Sequestration of the Gβγ Subunit to the Golgi Apparatus." Molecular and Cellular Biology 30, no. 1 (November 2, 2009): 78–90. http://dx.doi.org/10.1128/mcb.01038-09.
Full textNakagawa, Shumpei, Khanh Tien Nguyen Pham, Xinyan Shao, and Masao Doi. "Time-Restricted G-Protein Signaling Pathways via GPR176, Gz, and RGS16 Set the Pace of the Master Circadian Clock in the Suprachiasmatic Nucleus." International Journal of Molecular Sciences 21, no. 14 (July 17, 2020): 5055. http://dx.doi.org/10.3390/ijms21145055.
Full textTsiokas, Leonidas. "Function and regulation of TRPP2 at the plasma membrane." American Journal of Physiology-Renal Physiology 297, no. 1 (July 2009): F1—F9. http://dx.doi.org/10.1152/ajprenal.90277.2008.
Full textChiba, Yuta, Keigo Yoshizaki, Kan Saito, Tomoko Ikeuchi, Tsutomu Iwamoto, Craig Rhodes, Takashi Nakamura, et al. "G protein–coupled receptor Gpr115 (Adgrf4) is required for enamel mineralization mediated by ameloblasts." Journal of Biological Chemistry 295, no. 45 (August 31, 2020): 15328–41. http://dx.doi.org/10.1074/jbc.ra120.014281.
Full textSuchý, Tomáš, Christian Zieschang, Yulia Popkova, Isabell Kaczmarek, Juliane Weiner, Aenne-Dorothea Liebing, Mehmet Volkan Çakir, et al. "The repertoire of Adhesion G protein-coupled receptors in adipocytes and their functional relevance." International Journal of Obesity 44, no. 10 (March 19, 2020): 2124–36. http://dx.doi.org/10.1038/s41366-020-0570-2.
Full textKang, Jiuhong, Yufeng Shi, Bin Xiang, Bin Qu, Wenjuan Su, Min Zhu, Min Zhang, et al. "A Nuclear Function of β-Arrestin1 in GPCR Signaling: Regulation of Histone Acetylation and Gene Transcription." Cell 123, no. 5 (December 2005): 833–47. http://dx.doi.org/10.1016/j.cell.2005.09.011.
Full textKang, Jiuhong, Yufeng Shi, Bin Xiang, Bin Qu, Wenjuan Su, Min Zhu, Min Zhang, et al. "A Nuclear Function of β-Arrestin1 in GPCR Signaling: Regulation of Histone Acetylation and Gene Transcription." Cell 124, no. 3 (February 2006): 645. http://dx.doi.org/10.1016/j.cell.2006.01.029.
Full textRossi, Mario, Inigo Ruiz de Azua, Luiz F. Barella, Wataru Sakamoto, Lu Zhu, Yinghong Cui, Huiyan Lu, et al. "CK2 acts as a potent negative regulator of receptor-mediated insulin release in vitro and in vivo." Proceedings of the National Academy of Sciences 112, no. 49 (November 23, 2015): E6818—E6824. http://dx.doi.org/10.1073/pnas.1519430112.
Full textKunwar, Prabhat S., Hiroko Sano, Andrew D. Renault, Vitor Barbosa, Naoyuki Fuse, and Ruth Lehmann. "Tre1 GPCR initiates germ cell transepithelial migration by regulating Drosophila melanogaster E-cadherin." Journal of Cell Biology 183, no. 1 (September 29, 2008): 157–68. http://dx.doi.org/10.1083/jcb.200807049.
Full textYang, Li V., Caius G. Radu, Li Wang, Mireille Riedinger, and Owen N. Witte. "Gi-independent macrophage chemotaxis to lysophosphatidylcholine via the immunoregulatory GPCR G2A." Blood 105, no. 3 (February 1, 2005): 1127–34. http://dx.doi.org/10.1182/blood-2004-05-1916.
Full textLayden, B. T., V. Durai, M. V. Newman, A. M. Marinelarena, C. W. Ahn, G. Feng, S. Lin, et al. "Regulation of pancreatic islet gene expression in mouse islets by pregnancy." Journal of Endocrinology 207, no. 3 (September 16, 2010): 265–79. http://dx.doi.org/10.1677/joe-10-0298.
Full textHama, Taketsugu, and Frank Park. "Heterotrimeric G protein signaling in polycystic kidney disease." Physiological Genomics 48, no. 7 (July 1, 2016): 429–45. http://dx.doi.org/10.1152/physiolgenomics.00027.2016.
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