Relevant bibliographies by topics / GP9

Academic literature on the topic 'GP9'

Author: Grafiati
Published: 11 March 2023

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Journal articles on the topic "GP9"

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El-Naggar, Sabry Ali, Karim Samy El-Said, Mona Elwan, Maysa Mobasher, Fotouh Mansour, Mohamed Elbakry, and Doaa Ibrahim Kabil. "Toxicity of bean cooking media containing EDTA in mice." Toxicology and Industrial Health 36, no. 6 (June 2020): 436–45. http://dx.doi.org/10.1177/0748233719893178.

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The possible renal and hepatic toxicities of ethylenediaminetetraacetic acid (EDTA) in bean cooking media were studied using 100 male albino mice. Two sublethal doses of EDTA were used to explore their toxic effects; 20 mg/kg and 200 mg/kg, which corresponded to 1/100th and 1/10th of LD50, respectively. Accordingly, the toxicity study was performed using 50 mice, divided into five groups ( n = 10/group) as follows: group 1 (Gp1) served as a negative control and was orally administered normal saline; group 2 (Gp2) was administered the bean cooking medium; group 3 (Gp3) was administered EDTA (200 mg/kg); group 4 (Gp4) was administered bean cooking medium containing 20 mg/kg of EDTA; and group 5 (Gp5) was administered bean cooking medium containing 200 mg/kg of EDTA. The results showed no significant changes in liver and kidney functions in Gp2 while Gp3, Gp4, and Gp5 exhibited significant increases in adverse liver and kidney function markers. Hematocrit values were significantly decreased in Gp3 and Gp5, while the total white blood cells counts were significantly decreased in Gp3 and significantly increased in Gp5. The number of platelets was decreased in Gp3, Gp4, and Gp5. The blood levels of sodium (Na+), iron (Fe2+), and calcium (Ca2+) were decreased in Gp3, Gp4, and Gp5 due to the chelating effects of EDTA. The hepatic and renal architectures were disorganized in Gp3, Gp4, and Gp5 with some hemorrhagic manifestations in livers and kidneys of mice. These results demonstrate that EDTA in bean cooking is harmful in mice under the conditions of this study, and the potentially harmful effects in humans supports restricting its use.
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Elfaky, Mahmoud A., Alaa Sirwi, Sameh H. Ismail, Heba H. Awad, and Sameh S. Gad. "Hepatoprotective Effect of Silver Nanoparticles at Two Different Particle Sizes: Comparative Study with and without Silymarin." Current Issues in Molecular Biology 44, no. 7 (June 30, 2022): 2923–38. http://dx.doi.org/10.3390/cimb44070202.

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Silver nanoparticles have been used for numerous therapeutic purposes because of their increased biodegradability and bioavailability, yet their toxicity remains questionable as they are known to interact easily with biological systems because of their small size. This study aimed to investigate and compare the effect of silver nanoparticles’ particle size in terms of their potential hazard, as well as their potential protective effect in an LPS-induced hepatotoxicity model. Liver slices were obtained from Sprague Dawley adult male rats, and the thickness of the slices was optimized to 150 μm. Under regulated physiological circumstances, freshly cut liver slices were divided into six different groups; GP1: normal, GP2: LPS (control), GP3: LPS + AgNpL (positive control), GP4: LPS + silymarin (standard treatment), GP5: LPS + AgNpS + silymarin (treatment I), GP6: LPS + AgNpL + silymarin (treatment II). After 24 h of incubation, the plates were gently removed, and the supernatant and tissue homogenate were all collected and then subjected to the following biochemical parameters: Cox2, NO, IL-6, and TNF-α. The LPS elicited marked hepatic tissue injury manifested by elevated cytokines and proinflammatory markers. Both small silver nanoparticles and large silver nanoparticles efficiently attenuated LPS hepatotoxicity, mainly via preserving the cytokines’ level and diminishing the inflammatory pathways. In conclusion, large silver nanoparticles exhibited effective hepatoprotective capabilities over small silver nanoparticles.
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Kaur, Rajinder, Sandeep Kaur, Neelima R. Kumar, and Kusum Harjai. "Honey bee collected pollen and beebread of Zea mays: determination of bioactive constituents and health benefits." Research Journal of Biotechnology 18, no. 3 (February 15, 2023): 64–69. http://dx.doi.org/10.25303/1803rjbt64069.

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Bee products are known since ancient times for their nutritional value and beneficial effects. The present study was carried out to evaluate the phytochemical composition and therapeutic potential of bee pollen and beebread. Broth dilution method was used to observe the in vitro antibacterial activity. For in vivo antioxidant activities, BALB/c mice were divided into six groups; Gp1 was given normal saline only, Gp2 was injected intraperitoneally with Salmonella enterica serovar Typhimurium at 2×104 CFU/ml, Gp3 was administrated orally with bee collected pollen of Zea mays (250mg/kg bw) only, Gp4 was treated with the bee collected pollen of Z. mays (250mg/kg bw) in Salmonella infected mice, Gp5 was administrated orally with beebread of Z. mays (250mg/kg bw) only and Gp6 was treated with the beebread of Z. mays (250mg/kg bw) in Salmonella infected mice. The results obtained in the study suggested that various bioactive constituents were present in bee pollen and beebread and these phytochemical constituents were responsible for the antibacterial and antioxidant efficacy of these studied bee products. Beebread was found to possess high activity as compared to bee pollen reflecting its high polphenolic composition. Hence, it could be inferred that bee pollen could be seen as a potential source for designing a drug against S. typhimurium.
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Kaisarly, Dalia, D. Meierhofer, M. El Gezawi, P. Rösch, and K. H. Kunzelmann. "Effects of flowable liners on the shrinkage vectors of bulk-fill composites." Clinical Oral Investigations 25, no. 8 (January 27, 2021): 4927–40. http://dx.doi.org/10.1007/s00784-021-03801-2.

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Abstract Objectives This investigation evaluated the effect of flowable liners beneath a composite restoration applied via different methods on the pattern of shrinkage vectors. Methods Forty molars were divided into five groups (n = 8), and cylindrical cavities were prepared and bonded with a self-etch adhesive (AdheSe). Tetric EvoCeram Bulk Fill (TBF) was used as the filling material in all cavities. The flowable liners Tetric EvoFlow Bulk Fill (TEF) and SDR were used to line the cavity floor. In gp1-TBF, the flowable composite was not used. TEF was applied in a thin layer in gp2-fl/TEF + TBF and gp3-fl/TEF + TBFincremental. Two flowable composites with a layer thickness of 2 mm were compared in gp4-fl/TEF + TBF and gp5-fl/SDR + TBF. TEF and SDR were mixed with radiolucent glass beads, while air bubbles inherently present in TBF served as markers. Each material application was scanned twice by micro-computed tomography before and after light curing. Scans were subjected to image segmentation for calculation of the shrinkage vectors. Results The absence of a flowable liner resulted in the greatest shrinkage vectors. A thin flowable liner (gp2-fl/TEF + TBFbulk) resulted in larger overall shrinkage vectors for the whole restoration than a thick flowable liner (gp4-fl/TEF + TBF). A thin flowable liner and incremental application (gp3-fl/TEF + TBFincremental) yielded the smallest shrinkage vectors. SDR yielded slightly smaller shrinkage vectors for the whole restoration than that observed in gp4-fl/TEF + TBF. Conclusions Thick flowable liner layers had a more pronounced stress-relieving effect than thin layers regardless of the flowable liner type. Clinical relevance It is recommended to apply a flowable liner (thin or thick) beneath bulk-fill composites, preferably incrementally.
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Zhang, Jianqiang, Peter J. Timoney, N. James MacLachlan, William H. McCollum, and Udeni B. R. Balasuriya. "Persistent Equine Arteritis Virus Infection in HeLa Cells." Journal of Virology 82, no. 17 (June 25, 2008): 8456–64. http://dx.doi.org/10.1128/jvi.01249-08.

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ABSTRACT The horse-adapted virulent Bucyrus (VB) strain of equine arteritis virus (EAV) established persistent infection in high-passage-number human cervix cells (HeLa-H cells; passages 170 to 221) but not in low-passage-number human cervix cells (HeLa-L cells; passages 95 to 115) or in several other cell lines that were evaluated. However, virus recovered from the 80th passage of the persistently infected HeLa-H cells (HeLa-H-EAVP80) readily established persistent infection in HeLa-L cells. Comparative sequence analysis of the entire genomes of the VB and HeLa-H-EAVP80 viruses identified 16 amino acid substitutions, including 4 in the replicase (nsp1, nsp2, nsp7, and nsp9) and 12 in the structural proteins (E, GP2, GP3, GP4, and GP5). Reverse genetic studies clearly showed that substitutions in the structural proteins but not the replicase were responsible for the establishment of persistent infection in HeLa-L cells by the HeLa-H-EAVP80 virus. It was further demonstrated that recombinant viruses with substitutions in the minor structural proteins E and GP2 or GP3 and GP4 were unable to establish persistent infection in HeLa-L cells but that recombinant viruses with combined substitutions in the E (Ser53→Cys and Val55→Ala), GP2 (Leu15→Ser, Trp31→Arg, Val87→Leu, and Ala112→Thr), GP3 (Ser115→Gly and Leu135→Pro), and GP4 (Tyr4→His and Ile109→Phe) proteins or with a single point mutation in the GP5 protein (Pro98→Leu) were able to establish persistent infection in HeLa-L cells. In summary, an in vitro model of EAV persistence in cell culture was established for the first time. This system can provide a valuable model for studying virus-host cell interactions, especially virus-receptor interactions.
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Go, Yun Young, Jianqiang Zhang, Peter J. Timoney, R. Frank Cook, David W. Horohov, and Udeni B. R. Balasuriya. "Complex Interactions between the Major and Minor Envelope Proteins of Equine Arteritis Virus Determine Its Tropism for Equine CD3+ T Lymphocytes and CD14+ Monocytes." Journal of Virology 84, no. 10 (March 10, 2010): 4898–911. http://dx.doi.org/10.1128/jvi.02743-09.

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ABSTRACT Extensive cell culture passage of the virulent Bucyrus (VB) strain of equine arteritis virus (EAV) to produce the modified live virus (MLV) vaccine strain has altered its tropism for equine CD3+ T lymphocytes and CD14+ monocytes. The VB strain primarily infects CD14+ monocytes and a small subpopulation of CD3+ T lymphocytes (predominantly CD4+ T lymphocytes), as determined by dual-color flow cytometry. In contrast, the MLV vaccine strain has a significantly reduced ability to infect CD14+ monocytes and has lost its capability to infect CD3+ T lymphocytes. Using a panel of five recombinant chimeric viruses, we demonstrated that interactions among the GP2, GP3, GP4, GP5, and M envelope proteins play a major role in determining the CD14+ monocyte tropism while the tropism for CD3+ T lymphocytes is determined by the GP2, GP4, GP5, and M envelope proteins but not the GP3 protein. The data clearly suggest that there are intricate interactions among these envelope proteins that affect the binding of EAV to different cell receptors on CD3+ T lymphocytes and CD14+ monocytes. This study shows, for the first time, that CD3+ T lymphocytes may play an important role in the pathogenesis of equine viral arteritis when horses are infected with the virulent strains of EAV.
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Morel-Kopp, Marie-Christine, Jeannine M. Clemetson, Kenneth J. Clemetson, Riitta Kekomaki, Hartmut Kroll, Katerina Michaelides, Edward G. D. Tuddenham, Karen Vanhoorelbeke, Christopher M. Ward, and Hai Po Helena Liang. "A common ancestral glycoprotein (GP) 9 1828A>G (Asn45Ser) gene mutation occurring in European families from Australia and Northern Europe with Bernard-Soulier syndrome (BSS)." Thrombosis and Haemostasis 94, no. 09 (2005): 599–605. http://dx.doi.org/10.1160/th05-03-0165.

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SummaryBernard-Soulier syndrome (BSS) is an extremely rare hereditary bleeding disorder, caused by mutations occurring in the Glycoprotein (GP) Ibα, GPIbβ and GP9 genes that encode for the corresponding subunits of platelet GPIb-V-IX adhesion receptor complex. BSS has been reported in many populations, mostly behaving in an autosomal-recessive manner. While the great majority of BSS mutations are unique to a single individual or family, the GP9 1828A>G Asn45Ser mutation, which we have identified in an undocumented Australian Caucasian, has already been reported in multiple unrelated Caucasian families from various Northern and Central European countries. Haplotype analysis of 19 BSS patients from 15 unrelated Northern European families (including 2 compound heterozygote siblings from a British family previously published, and 17 1828A>G Asn45Ser homozygotes), showed that 14 of these BSS patients from 11 of the 1828A>G Asn45Ser homozygote families share a common haplotype at the chromosomal region 3’ to the GP9 gene. Hence, the results suggest that the GP9 1828A>GAsn45Ser mutation in these families is ancient, and its frequent emergence in the European population is the result of a founder effect rather than recurrent mutational events. Association of the 1828A>G Asn45Ser mutation with variant haplotypes in 4 other Northern European BSS families raised the possibility of a second founder event, or rare recombinations in these families. Additional members from these ‘atypical’ lineages would need to be screened to resolve this question.
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Human, M.Sc, Prof Dr Soeranto, S. Loekito, M. Trilaksono, and A. Syaifudin. "Pemuliaan Mutasi Tanaman Nanas (Ananas comosus (L.) Merr.) Menggunakan Iradiasi Gamma untuk Perbaikan Varietas Nanas Smooth Cayenne." Jurnal Ilmiah Aplikasi Isotop dan Radiasi 12, no. 1 (January 31, 2017): 13. http://dx.doi.org/10.17146/jair.2016.12.1.3197.

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Pemuliaan Mutasi Tanaman Nanas (Ananas comosus (L.) Merr.) Menggunakan Iradiasi Gamma untuk Perbaikan Varietas Smooth Cayenne. Pada saat ini, jenis nanas yang paling banyak dibudidayakan dalam berbagai perdagangan dunia adalah jenis Smooth Cayenne. Banyak klon yang berasal dari kultivar ini seperti GP1, GP2, GP3, GP4, GP5, dan F180 ditanam oleh GGP baik untuk buahsegar dan olahan. GGPC mulai melakukan usaha perbaikan varietas nanas sejak tahun 1986, yaitu dengan tujuan meningkatkan kualitas dan produksi yang tinggi. Pemuliaan mutasi nanas dimulai pada tahun 2006, yaitu melalui kerjasama dengan Pusat Aplikasi Isotop dan Radiasi (PAIR), Badan Tenaga Nuklir Nasional (BATAN). Sejumlah 10 mahkota (crown) nanas berasal dari GP2, GP3 (A10) dan klon F180 diiradiasi sinar gamma bersumber Cobalt-60 terpasang pada iradiator gamma chamber 4000A dengan dosis 200 dan 300 Gy. Crown yang telah diradiasi kemudian ditanam di lahan percobaan dengan mengikuti budidaya standar komersial di PT. GGPC. Secara umum hasil penelitian menunjukkan tidak ada perbedaan yang signifikan antara kedua dosis iradiasi (200 dan 300 Gy) pada fenotipe tanaman. Namun, keragaman fenotipe yang sangat tinggi dijumpai pada klon turunan tanaman vegetatif (V1). Beberapa variasi tanaman yang muncul tercatat sebagai berikut: 47% tanaman normal, 15% Rosset, 11% berduri, 5% crown bercabang, 4% tanaman memiliki banyak daun dan 18% buah berbentuk abnormal. Variasi mutan yang signifikan juga diamati pada klon-lon turunan tanaman V2 dan beberapa mutan tampak lebih stabil pada generasi V3. Program pemuliaan nanas ini akan terus dilanjutkan untuk evaluasi yang berkaitan dengan perbaikan produktivitas, kualitas, dan ketahanan terhadap hama dan penyakit tertentu.
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Wieringa, Roeland, Antoine A. F. de Vries, Jannes van der Meulen, Gert-Jan Godeke, Jos J. M. Onderwater, Hans van Tol, Henk K. Koerten, A. Mieke Mommaas, Eric J. Snijder, and Peter J. M. Rottier. "Structural Protein Requirements in Equine Arteritis Virus Assembly." Journal of Virology 78, no. 23 (December 1, 2004): 13019–27. http://dx.doi.org/10.1128/jvi.78.23.13019-13027.2004.

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ABSTRACT Equine arteritis virus (EAV) is an enveloped, positive-stranded RNA virus belonging to the family Arteriviridae of the order Nidovirales. EAV particles contain seven structural proteins: the nucleocapsid protein N, the unglycosylated envelope proteins M and E, and the N-glycosylated membrane proteins GP2b (previously named GS), GP3, GP4, and GP5 (previously named GL). Proteins N, M, and GP5 are major virion components, E occurs in virus particles in intermediate amounts, and GP4, GP3, and GP2b are minor structural proteins. The M and GP5 proteins occur in virus particles as disulfide-linked heterodimers while the GP4, GP3, and GP2b proteins are incorporated into virions as a heterotrimeric complex. Here, we studied the effect on virus assembly of inactivating the structural protein genes one by one in the context of a (full-length) EAV cDNA clone. It appeared that the three major structural proteins are essential for particle formation, while the other four virion proteins are dispensable. When one of the GP2b, GP3, or GP4 proteins was missing, the incorporation of the remaining two minor envelope glycoproteins was completely blocked while that of the E protein was greatly reduced. The absence of E entirely prevented the incorporation of the GP2b, GP3, and GP4 proteins into viral particles. EAV particles lacking GP2b, GP3, GP4, and E did not markedly differ from wild-type virions in buoyant density, major structural protein composition, electron microscopic appearance, and genomic RNA content. On the basis of these results, we propose a model for the EAV particle in which the GP2b/GP3/GP4 heterotrimers are positioned, in association with a defined number of E molecules, above the vertices of the putatively icosahedral nucleocapsid.
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Olson, N. H., W. Xu, W. D. Grochulski, D. L. Andersont, and T. S. Baker. "Electron Microscopy of Negatively Stained and Frozen-Hydrated Bacteriophage Φ29." Proceedings, annual meeting, Electron Microscopy Society of America 48, no. 1 (August 12, 1990): 270–71. http://dx.doi.org/10.1017/s0424820100180100.

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Bacteriophage Φ29 is a complex-shaped, double-stranded DNA virus that infects Bacillus subtilis . Mature Φ29 particles contain six major structural proteins which give rise to several distinctive features: a prolate-shaped head (gp8), fibers (gp8.5) which radiate from the head, a connector-collar region (gp10 and gp11), collar appendages (gp12*) and a tail (gp9). Although much is known about Φ29 biochemistry, genetics and assembly, relatively little is known about its detailed structure. Three-dimensional reconstructions of the collar demonstrated that it contains two structurally distinct features: an upper portion (proximal to the head) with 12-fold axial symmetry (gp10) and a lower protion with 6-fold symmetry (possibly both gp10 and gp11). The capsid is believed to be organized with two apical regions with trimeric aggregates of gp8 dimers arranged on a T=l icosahedral lattice separated by 10 additional trimers in the equatorial region. Φ29 proheads are assembly intermediates that contain only gp8, gp8.5, gp10 and the scaffolding protein (gp7) which is released upon DNA encapsidation. We have imaged Φ29 with conventional negative-staining and the recently developed cryo-microscopy techniques with the goal of examining the structural basis for Φ29 morphogenesis.Vitrified Φ29 proheads display distinct outlines with one end pointed and the other somewhat flattened and they often orient with their long axes in the plane of the vitreous water (Fig. 1). Occasional end-on views with a circular profile are also observed. Proheads show a tendency to associate in pairs with the closest contact between the flattened ends (Fig. 1, arrow-head). Longer morphological variants are also occassionally observed (Fig. 1, arrow). The morphology of proheads is dramatically distorted in negative-stain preparations indicating significantly poorer preservation using this technique (Fig. 2). Proheads are also permeable to stain.
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Dissertations / Theses on the topic "GP9"

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Balaji, Chandra Sekhar Sinhadri [Verfasser]. "Expression and characterization of spike protein complexes Gp2/Gp3/Gp4 and Gp5/M of the Arterivirus / Sekhar Sinhadri Balaji Chandra." Berlin : Freie Universität Berlin, 2015. http://d-nb.info/1071843435/34.

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Srnec, Erik. "Výpočet optického pole v GP-GPU." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2012. http://www.nusl.cz/ntk/nusl-235472.

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This work describes a relatively new technique designed to write highly parallel programs, that name is OpenCL. It is intended for both GPU and CPU and other parallel processors. Libraries used by the processor architecture, which includes a large number of small cores. These cores are not as comprehensive as conventional processors and is therefore suitable for calculations, which are many and they are simple. It is this property could, under certain conditions, accelerate the calculation of the hologram, namely the calculation of the optical field. While the calculation itself is simple, but the amount of processed data is large and therefore slow. The work also contain the basic concepts of explanation of optical and digital holography.
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Kula, Michal. "Algoritmy grafiky a video v GP-GPU." Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2013. http://www.nusl.cz/ntk/nusl-236364.

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This diploma thesis is focused on object detections through general-purpose computing on graphics processor units. There is an explanation of graphics adapters work and basics of their architecture in this thesis. Based on the adapters, there is the effective work in libraries for general-purpose computing on graphics processor units demonstrated in this thesis. Further, the thesis shows the available algorithms for object detection and which ones from them are possible to be effectively parallelized. In conclusion of this thesis, there is a comparison of the object detections speeds to common implementations on classical processors.
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Nottingham, Alastair. "GPF : a framework for general packet classification on GPU co-processors." Thesis, Rhodes University, 2012. http://hdl.handle.net/10962/d1006662.

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This thesis explores the design and experimental implementation of GPF, a novel protocol-independent, multi-match packet classification framework. This framework is targeted and optimised for flexible, efficient execution on NVIDIA GPU platforms through the CUDA API, but should not be difficult to port to other platforms, such as OpenCL, in the future. GPF was conceived and developed in order to accelerate classification of large packet capture files, such as those collected by Network Telescopes. It uses a multiphase SIMD classification process which exploits both the parallelism of packet sets and the redundancy in filter programs, in order to classify packet captures against multiple filters at extremely high rates. The resultant framework - comprised of classification, compilation and buffering components - efficiently leverages GPU resources to classify arbitrary protocols, and return multiple filter results for each packet. The classification functions described were verified and evaluated by testing an experimental prototype implementation against several filter programs, of varying complexity, on devices from three GPU platform generations. In addition to the significant speedup achieved in processing results, analysis indicates that the prototype classification functions perform predictably, and scale linearly with respect to both packet count and filter complexity. Furthermore, classification throughput (packets/s) remained essentially constant regardless of the underlying packet data, and thus the effective data rate when classifying a particular filter was heavily influenced by the average size of packets in the processed capture. For example: in the trivial case of classifying all IPv4 packets ranging in size from 70 bytes to 1KB, the observed data rate achieved by the GPU classification kernels ranged from 60Gbps to 900Gbps on a GTX 275, and from 220Gbps to 3.3Tbps on a GTX 480. In the less trivial case of identifying all ARP, TCP, UDP and ICMP packets for both IPv4 and IPv6 protocols, the effective data rates ranged from 15Gbps to 220Gbps (GTX 275), and from 50Gbps to 740Gbps (GTX 480), for 70B and 1KB packets respectively.
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Cellier, Fabien. "Modélisation et calcul parallèle pour le Web SIG 3D." Thesis, Lyon 1, 2014. http://www.theses.fr/2014LYO10015/document.

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Cette thèse est centrée sur l'affichage et la manipulation en temps interactif au sein d'un navigateur Internet de modèles 3D issus de Systèmes d'Informations Géographiques (SIG). Ses principales contributions sont la visualisation de terrains 3D haute résolution, la simplification de maillages irréguliers sur GPU, et la création d'une nouvelle API navigateur permettant de réaliser des traitements lourds et efficaces (parallélisme GP/GPU) sans compromettre la sécurité. La première approche proposée pour la visualisation de modèles de terrain s'appuie sur les récents efforts des navigateurs pour devenir une plateforme versatile. Grâce aux nouvelles API 3D sans plugin, nous avons pu créer un client de visualisation de terrains "streamés" à travers HTTP. Celui-ci s'intègre parfaitement dans les écosystèmes Web-SIG actuels (desktop et mobile) par l'utilisation des protocoles standards du domaine (fournis par l'OGC, Open Geospatial Consortium). Ce prototype s'inscrit dans le cadre des partenariats industriels entre ATOS Worldline et ses clients SIG, et notamment l'IGN (institut national de l'information géographique et forestière) avec le Géoportail (http://www.geoportail.gouv.fr) et ses API cartographiques. La 3D dans les navigateurs possède ses propres défis, qui sont différents de ce que l'on connaît des applications lourdes : aux problèmes de transfert de données s'ajoutent les restrictions et contraintes du JavaScript. Ces contraintes, détaillées dans le paragraphe suivant, nous ont poussé à repenser les algorithmes de référence de visualisation de terrain afin de prendre en compte les spécificités dues aux navigateurs. Ainsi, nous avons su profiter de la latence du réseau pour gérer dynamiquement les liaisons entre les parties du maillage sans impacter significativement la vitesse du rendu. Au-delà de la visualisation 3D, et bien que le langage JavaScript autorise le parallélisme de tâches, le parallélisme de données reste quasi inexistant au sein des navigateurs Web. Ce constat, couplé à la faiblesse de traitement du JavaScript, constituait un frein majeur dans notre objectif de définir une plateforme SIG complète et performante intégrée au navigateur. C'est pour cette raison que nous avons conçu et développé, à travers les WebCLWorkers, une API Web de calcul GP/GPU haute performance répondant aux critères de simplicité et de sécurité inhérents au Web. Contrairement à l'existant, qui se base sur des codes déjà précompilés ou met de côté les performances, nous avons tenté de trouver le bon compromis pour avoir un langage proche du script mais sécurisé et performant, en utilisant les API OpenCL comme moteur d'exécution. Notre proposition d'API a intéressé la fondation Mozilla qui nous a ensuite demandé de participer à l'élaboration du standard WebCL dans la cadre du groupe Khronos, (aux côtés de Mozilla mais aussi de Samsung, Nokia, Google, AMD, etc.). Grâce aux nouvelles ressources de calcul ainsi obtenues, nous avons alors proposé un algorithme de simplification parallèle de maillages irréguliers. Alors que l'état de l'art repose essentiellement sur des grilles régulières pour le parallélisme (hors Web) ou sur la simplification via clusterisation et kd-tree, aucune solution ne permettait d'avoir à la fois une simplification parallèle et des modèles intermédiaires utilisables pour la visualisation progressive en utilisant des grilles irrégulières. Notre solution repose sur un algorithme en trois étapes utilisant des priorités implicites et des minima locaux afin de réaliser la simplification, et dont le degré de parallélisme est linéairement lié au nombre de points et de triangles du maillage à traiter [etc...]GP/GPU
This thesis focuses on displaying and manipulating 3D models from Geographic Information Systems (GIS) in interactive time directly in a web browser. Its main contributions are the visualization of high resolution 3D terrains, the simplification of irregular meshes on the GPU, and the creation of a new API for performing heavy and effective computing in the browser (parallelism GP/GPU) without compromising safety. The first approach proposed for the visualization of terrain models is built on recent browsers efforts to become a versatile platform. With the new 3D pluginless APIs, we have created a visualization client for terrain models “streamed” through HTTP. It fits perfectly into the current Web-GIS ecosystem (desktop and mobile) by the use of the standard protocols provided by OGC Open Geospatial Consortium. This prototype is part of an industrial partnership between ATOS Wordline and its GIS customer, and particularly the IGN (French National Geographic Institute) with the Geoportail application (http://www.geoportail.gouv.fr) and its mapping APIs. The 3D embedded in browsers brings its own challenges which are different from what we know in heavy applications: restrictions and constraints from JavaScript but also problems of data transfer. These constraints, detailed in the next paragraph, led us to rethink the standard algorithms for 3D visualization to take into account the browser specificities. Thus, we have taken advantage of network latency to dynamically manage the connections between the different parts of the mesh without significantly impacting the rendering speed. Beyond 3D visualization, and even if the JavaScript language allows task parallelism, data parallelism remains absent from Web browsers. This observation, added to the slowness of JavaScript processing, constituted a major obstacle in our goal to define a complete and powerful GIS platform integrated in the browser. That is why we have designed and developed the WebCLWorkers, a GP/GPU Web API for high performance computing that meets the criteria of simplicity and security inherent to the Web. We tried to find a trade-off for a language close to the script but secure and efficient, based on the OpenCL API at runtime. This approach is opposite to the existing ones, which are either based on precompiled code or disregard performances. Our API proposal interested the Mozilla Foundation which asked us to participate in the development of the WebCL standard by integrating the Khronos Group (Mozilla, Samsung, Nokia, Google, AMD, and so on). Exploiting these new computing resources, we then suggested an algorithm for parallel simplification of irregular meshes. While the state of the art was mainly based on regular grids for parallelism (and did not take into account Web browsers restrictions) or on simplification and kd-tree clustering, no solution could allow both parallel simplification and progressive visualization using irregular grids. Our solution is based on a three-step algorithm using implicit priorities and local minima to achieve simplification, and its degree of parallelism is linearly related to the number of points and triangles in the mesh to process. We have proposed in the thesis an innovative approach for 3D WebGIS pluglinless visualization, offering tools that bring to the browser a comfortable GP/GPU computing power, and designing a method for irregular meshes parallel simplification allowing to visualize level of details directly in Web browsers. Based on these initial results, it becomes possible to carry all the rich functionalities of desktop GIS clients to Web browsers, on PC as well as mobile phones and tablets
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Leksell, Torbjörn. "A Comparison of Smartphone GPSL1 and Galileo E1-B/C Spoofing Resilience." Thesis, KTH, Skolan för elektroteknik och datavetenskap (EECS), 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-292950.

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Location-based services have grown in importance as smartphones, and location-based applications have become an integral part of everyday life. While Global Navigation Satellite Systems (GNSSs) provide the most accurate position determination, open service GNSS signals remain unprotected and susceptible to spoofing attacks. Previous work within the domain highlighted this issue, with many smartphone receivers shown susceptible to GPS L1 spoofing, suggesting that their resilience experiments should be extended to include other GNSS signals in the future. Given that multi-GNSS receivers now have become the norm in smartphones, this thesis investigates whether smartphone GNSS receiver spoofing resilience depends on the type of signal; by conducting a series of comparative spoofing experiments involving GPS L1 and Galileo E1-B/C signals. To conduct the experiments, we developed a Galileo E1-B/C signal simulator that, together with the open-source GPS-SDR-SIM signal simulator, was the basis for conducting a series of experiments designed to identify the potential presence of anti-spoofing measures. The result of our experiments indicates that smartphone multi-GNSS receivers were significantly more resilient towards Galileo E1-B/C spoofing attacks, often accepting GPS L1 signals with significant position, time, and data errors, while refusing to accept corresponding Galileo E1-B/C signals. While we never observed cases of E1-B/C signals being accepted while rejecting GPS L1 signals, external factors limited the scope of the investigation and do not allow a generalized conclusion. As such, to deepen our understanding of these issues and how they relate to the development of anti-spoofing measures and trust in different signals, it is essential to extend this research to include more devices and other GNSS signals.
Positionstjänster har växt i betydelse allteftersom smarttelefoner och positionsapplikationer har blivit en integral del av våran vardag. Även om satellitpositionering utger det mest precisa och vedertagna positionsbestämningen av tillgängliga positionstjänser så är de publika satellitnavigeringssignalarna oskyddade och sårbara för förfalskningsattacker. Tidigare forskning inom området har evaluerat dessa sårbarheter och visat att ett betydande antal smarttelefoner var sårbara för GPS-L1 förfalskningsattacker och att denna forskning borde utökas i framtiden allteftersom satellitnavigeringsmottagare med förmåga att mottaga olika satellitsignaler integreras i smarttelefoner. Givet att en majoritet av nya smarttelefoner nu integrerar denna typ av mottagare så utvärderar detta arbete hur sårbarheten mot förfalskningsattacker beror på typ av satellitsignal genom en komparativ jämförelse av sårbarhet mellan GPS-L1 och den nyare Galileo E1-B/C signalen. För att genomföra utvärderingen så utvecklade vi en Galileo E1-B/C signalsimulator som tillsammans med GPS-L1 signalsimulatorn (GPS-SDR-SIM) utgjorde grunden för en serie av experiment designade för att identifiera och utvärdera sårbarheter och potentiella motåtgärder i smarttelefoner. Våra resultat indikerar att smarttelefoner är betydligt mer sårbara for GPS-L1 forfalskningsattacker då de accepterade GPS-L1 signaler med betydande position, tid, och datafel medans motsvarande Galileo E1-B/C signaler ej accepterades. Trots resultaten så är det viktigt att inte dra för starka slutsatser då underlaget var kraftigt begränsat givet rådande omständigheter (Covid), som gjorde det svårt/omöjligt att på ett säkert sätt samla volontärer med olika smarttelefoner för våra experiment. Därav så är det viktigt att i framtiden utöka arbetet med ett större underlag och fler signaltyper.
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De, Rocco Daniela, and Rocco Daniela De. "STUDIO CLINICO E MOLECOLARE DELLA SINDROME DI BERNARD-SOULIER." Doctoral thesis, Università degli studi di Trieste, 2015. http://hdl.handle.net/10077/10848.

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2013/2014
2013/2014
La sindrome di Bernard-Soulier (BSS) è una rara piastrinopenia ereditaria causata da alterazioni a livello del complesso glicoproteico GPIb-IX-V, presente sulla membrana piastrinica e responsabile della adesione delle piastrine in seguito a danno vascolare. La BSS si trasmette come malattia autosomica recessiva (BBSA1) e i pazienti affetti presentano piastrine giganti e severi episodi di sanguinamento. Tuttavia in tempi recenti sono state descritte delle famiglie con una forma dominante nota come BSSA2. In questi pazienti la piastrinopenia è moderata e le piastrine presentano un volume leggermente aumentato. Finora sono state individuate solo 5 varianti in eterozigosi nel BSSA2:, 4 nel gene GP1BA e 1 in GP1BB. Fatta eccezione per p.Ala172Val del gene GP1BA che è relativamente frequente nella la popolazione Italiana, le altre 4 sono state descritte in singole famiglie. I pochi casi di cui disponiamo, soprattutto per la forma recessiva non ci permettono di avere informazioni sui meccanismi patogenetici e sulla sua evoluzione nel tempo. Per questo motivo è stato istituito un Consorzio Internazionale per lo studio della BSS grazie al quale è stato possibile raccogliere i dati clinici e molecolari di 132 famiglie. Tutte le informazioni sono state inserite in un database (BSS Consortium database) attualmente gestito dal nostro laboratorio e consultabile dai gruppi di studio che hanno aderito al Consorzio. Inoltre per aumentare le informazioni sulle varianti identificate nel BSSA1 abbiamo incrementato i dati molecolari delle famiglie del Consorzio con i dati di altre 79 famiglie descritte in letteratura, raggiungendo un totale di 211 famiglie. Tutte le mutazioni identificate in queste famiglie sono state poi inserite in un database pubblico disponibile in rete (LOVD: Leiden Open Variation Database). La raccolta e l’elaborazione dei dati ci ha permesso di chiarire alcuni aspetti clinici e molecolari della malattia. Tuttavia data l’eterogeneità genetica e l’elevata espressione fenotipica gli studi genotipo-fenotipo si sono rivelati difficili da eseguire. Nonostante le molte informazioni acquisite, il database risulta ancora incompleto e limitato; per questo motivo è necessario raccogliere nuovi casi e inserire assieme alle varianti anche i relativi studi funzionali che si rivelano indispensabili per poter definire l’effetto delle varianti sul complesso GPIb-IX-V. Nell’ambito invece dello studio e caratterizzazione della forma meno grave di BSS (BSSA2) sono stati selezionati 120 pazienti piastrinopenici senza diagnosi caratterizzati da piastrine grandi. In questi pazienti sono stati analizzati i geni GP1BA, GP1BB e GP9 e sono state identificate 11 diverse varianti: 1 nonsense, 2 mutazioni di framshift, 1 mutazione nel codone di inizio e 5 varianti missense. Gli studi funzionali eseguiti sulle varianti missense per stabilire il loro ruolo patogenetico sono ancora in corso. Tuttavia se gli studi dovessero confermare la loro patogenicità 11 pazienti su 120 risulterebbero BSSA2 e questa forma dovrebbe essere considerata una tra le piastrinopenie ereditarie più frequenti in Italia. In conclusione grazie a questo studio è stato possibile raccogliere la più ampia casistica di pazienti affetti da BSSA1 fin’ora descritta e ottenere numerose informazioni sia sulla clinica che sulle mutazioni coinvolte. Il BSS Consortium database permetterà ai clinici che hanno partecipato allo studio di osservare nel tempo l’andamento della malattia nei pazienti e di ottenere informazioni utili per stabilire un corretto protocollo per la presa in carico dei pazienti. Infine la caratterizzazione di nuove forme di BSSA2 rappresenta il punto di partenza per descrivere al meglio la malattia BSSA2 sia dal punto di vista clinico che molecolare. In futuro sarà quindi indispensabile estendere il BSS Consortium database anche alla forma BSSA2.
XXVII Ciclo
XXVII Ciclo
1979
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8

RAHUEL, CECILE. "Etude de la famille de genes codant pour les glycophorines a, b et e humaines : analyses structurales et bases moleculaires de la regulation transcriptionnelle et post-transcriptionnelle de l'expression des genes gpa, gpb et gpe." Paris 7, 1998. http://www.theses.fr/1998PA077133.

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Les glycophorines a (gpa) et b (gpb) sont les sialoglycoproteines majeures de la membrane du globule rouge. Elles portent respectivement les antigenes de groupe sanguin mn et ss. Nous avons etudie la structure des genes gpa et gpb, et mis en evidence un troisieme gene, gpe, membre de la meme famille. Les trois genes sont organises dans le sens 5 gpa-gpb-gpe 3, et definissent le locus gyp situe sur le chromosome 4, en position q28-31. Les genes sont extremement homologues entre eux, sauf pour les parties 3 non-codantes des genes gpb et gpe qui divergent completement de la sequence 3 non-codante du gene gpa. Cette divergence est due a une recombinaison entre des sequences alu apres duplication du gene gpa ancestral. Nous avons clone et analyse les sequences promotrices des trois genes sur 350 nt en amont du site d'initiation de la transcription, et montre qu'elles ne presentent que quelques mutations ponctuelles les unes par rapport aux autres. Nous avons mis en evidence que ces divergences n'influaient pas sur les taux de transcription des trois genes tout-a-fait comparables entre eux. Par contre, nous avons montre que des differences de stabilite des arn messagers correspondant aux trois genes peuvent rendre compte des differents taux d'arnm et des differences d'expression des glycophorines abe sur la membrane erythrocytaire. Nous avons analyse de maniere detaillee le promoteur gpb, et mis en evidence les sequences en cis, et les facteurs en trans impliques dans l'initiation de la transcription, le niveau d'expression et la specificite erythroide de l'expression du gene. Cette derniere analyse nous a permis de definir un modele de regulation, ou un represseur inhibe la transcription du gene dans les tissus non erythroides, et ou hgata-1, un facteur erythroide, deplace le facteur inhibiteur par competition et leve ainsi la repression dans les tissus erythroides.
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Ludvíček, Pavel. "Pokročilé metody řízení trajektorie modelu stanice v prostředí OPNET Modeler." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2011. http://www.nusl.cz/ntk/nusl-219354.

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The aim of this work is to study and theoretically process existing movement options of station in OPNET Modeler environment. These options are described in first part. Furthermore to design and implement function to display path obtained from real-world conditions and done to station following this route during simulation. Coordinates used to move station are obtained by GPX format, which is used to store clearly the GPS coordinates. Second part is devoted to describing creation of this function, first using PHP script, then direct implementation into OPNET Modeler environment using C++.
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Thomopulos, Nikos. "Sviluppo e sperimentazione di algoritmi per la soluzione di sistemi lineari su GP-GPU." Master's thesis, Alma Mater Studiorum - Università di Bologna, 2020.

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Gli ultimi anni hanno visto un incremento rilevante nella diffusione e utilizzo delle General Purpose Graphics Processing Unit (GP-GPU), unità di elaborazione grafica ad elevate performance. Tale diffusione è principalmente dovuta al vantaggioso rapporto tra la capacità computazione offerta da questi device ed il loro costo. Molto diffusi sono anche i problemi con sistemi lineari di grandi dimensioni, specialmente in ambito scientifico, e richiedono grandi capacità di calcolo per essere risolti in tempi brevi. Grazie alle loro performance computazionali le GP-GPU possono essere usate per velocizzare la soluzione di questi sistemi. In questo trattato si vuole sviluppare algoritmi per la soluzione di sistemi lineari che lavorino su Graphics Processing Unit (GPU) e sperimentarne le performance confrontandole con algoritmi preesistenti. L’obbiettivo è la realizzazione di soluzioni per applicazioni High Performance Computing (HPC) in grado di avvantaggiarsi significativamente della potenza di calcolo aggiuntiva fornita dalle GPU cosicché riescano ad ottenere miglioramenti significativi in termini di performance rispetto alle tradizionali applicazioni per CPU in problemi applicativi reali: la soluzione di piccoli e grandi sistemi lineari. La tesi proposta è incentrata sull’implementazione di algoritmi basati sull’Inhibition Method. La tecnologia utilizzata per lo sviluppo e il testing delle implementazioni è la Compute Unified Device Architecture (CUDA), attualmente la tecnologia maggiormente impiegata da chi lavora nell’ambito GP-GPU. In particolare, mostrerò il funzionamento di CUDA, i suoi punti di forza e di debolezza e come poter trarre vantaggio dal suo utilizzo nonché le strategie che conviene adottare per impiegarne al meglio le risorse e sfruttare al massimo le capacità. Presenterò dunque diverse implementazioni di algoritmi per la soluzione di sistemi lineari in svariate versioni e le confronterò con lo stato dell’arte per verificarne la validità.
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Books on the topic "GP9"

1

British Medical Association. General Medical Services Committee. Working in GP and community hospitals: Guidance for GPs. [London]: British Medical Association, 1996.

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National civilian GPS services: Global Positioning System (GPS), GPS augmentations, GPS modernization. 2nd ed. [Washington, D.C.]: U.S. Department of Transportation, 2000.

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United States. Dept. of Transportation, ed. National civilian GPS services: Global Positioning System (GPS), GPS augumentations, GPS modernization. [Washington, D.C.]: U.S. Dept. of Transportation, 2000.

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Xu, Guochang, and Yan Xu. GPS. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-50367-6.

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GPS. Madrid: Amargord, 2014.

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Prentzas, G. S. GPS. Ann Arbor, Mich: Cherry Lake Pub., 2009.

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Frank Stephen Tromp Van Diggelen. A-GPS: Assisted GPS, GNSS, and SBAS. Boston: Artech House, 2009.

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Kingsley-Hughes, Kathie. Hacking GPS. New York: John Wiley & Sons, Inc., 2005.

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Kötter, Wolfgang, Martin Schwarz-Kocher, and Christoph Zanker, eds. Balanced GPS. Wiesbaden: Springer Fachmedien Wiesbaden, 2015. http://dx.doi.org/10.1007/978-3-658-03515-0.

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Doyle, David. GPA/DUKW. Carrollton, TX: Squadron/Signal Publications, 2008.

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Book chapters on the topic "GP9"

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Yang, Kaifeng, and Michael Affenzeller. "Surrogate-assisted Multi-objective Optimization via Genetic Programming Based Symbolic Regression." In Lecture Notes in Computer Science, 176–90. Cham: Springer Nature Switzerland, 2023. http://dx.doi.org/10.1007/978-3-031-27250-9_13.

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AbstractSurrogate-assisted optimization algorithms are a commonly used technique to solve expensive-evaluation problems, in which a regression model is built to replace an expensive function. In some acquisition functions, the only requirement for a regression model is the predictions. However, some other acquisition functions also require a regression model to estimate the “uncertainty” of the prediction, instead of merely providing predictions. Unfortunately, very few statistical modeling techniques can achieve this, such as Kriging/Gaussian processes, and recently proposed genetic programming-based (GP-based) symbolic regression with Kriging (GP2). Another method is to use a bootstrapping technique in GP-based symbolic regression to estimate prediction and its corresponding uncertainty. This paper proposes to use GP-based symbolic regression and its variants to solve multi-objective optimization problems (MOPs), which are under the framework of a surrogate-assisted multi-objective optimization algorithm (SMOA). Kriging and random forest are also compared with GP-based symbolic regression and GP2. Experiment results demonstrate that the surrogate models using the GP2 strategy can improve SMOA’s performance.
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Shenoy, Govind Sreekar. "Memory Characterization of GP-GPU Applications." In Research Advances in Network Technologies, 65–73. Boca Raton: CRC Press, 2023. http://dx.doi.org/10.1201/9781003320333-5.

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Xu, Guochang, and Yan Xu. "Introduction." In GPS, 1–15. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-50367-6_1.

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Xu, Guochang, and Yan Xu. "Applications of GPS Theory and Algorithms." In GPS, 313–40. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-50367-6_10.

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Xu, Guochang, and Yan Xu. "Perturbed Orbit and Its Determination." In GPS, 341–408. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-50367-6_11.

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Xu, Guochang, and Yan Xu. "Singularity-Free Orbit Theory." In GPS, 409–37. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-50367-6_12.

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Xu, Guochang, and Yan Xu. "Discussions." In GPS, 439–43. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-50367-6_13.

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Xu, Guochang, and Yan Xu. "Coordinate and Time Systems." In GPS, 17–36. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-50367-6_2.

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Xu, Guochang, and Yan Xu. "Satellite Orbits." In GPS, 37–53. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-50367-6_3.

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Xu, Guochang, and Yan Xu. "GPS Observables." In GPS, 55–61. Berlin, Heidelberg: Springer Berlin Heidelberg, 2016. http://dx.doi.org/10.1007/978-3-662-50367-6_4.

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Conference papers on the topic "GP9"

1

O’Sullivan, Hugh, Shirley Bracken, John Caird, Louise Kyne, Dylan Murray, and Jodie Doyle. "GP9 Skull X-rays in the diagnosis of abnormal skull shapes." In Faculty of Paediatrics of the Royal College of Physicians of Ireland, 9th Europaediatrics Congress, 13–15 June, Dublin, Ireland 2019. BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health, 2019. http://dx.doi.org/10.1136/archdischild-2019-epa.76.

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Paul, Johns, Jiong He, and Bingsheng He. "GPL." In SIGMOD/PODS'16: International Conference on Management of Data. New York, NY, USA: ACM, 2016. http://dx.doi.org/10.1145/2882903.2915224.

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Huang, Yan, Shaoran Li, Y. Thomas Hou, and Wenjing Lou. "GPF." In MobiCom '18: The 24th Annual International Conference on Mobile Computing and Networking. New York, NY, USA: ACM, 2018. http://dx.doi.org/10.1145/3241539.3241552.

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He, Xiyuan, and Zhuohao Zhang. "GPK." In CHI '19: CHI Conference on Human Factors in Computing Systems. New York, NY, USA: ACM, 2019. http://dx.doi.org/10.1145/3290607.3308457.

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Bañas, Andrew R., Mark J. Villangca, Darwin Palima, and Jesper Glückstad. "Dark GPC." In SPIE OPTO, edited by Jesper Glückstad, David L. Andrews, and Enrique J. Galvez. SPIE, 2016. http://dx.doi.org/10.1117/12.2216180.

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Purdon, A. D., and J. B. Smith. "RELEASE AND TRANSACYLATION OF ARACHIDONATE FROM A COMMON POOL OF 1-ACYL-2-ARACHIDONOYL GLYCEROPHOSPHOCHOLINE IN HUMAN PLATELETS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643391.

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We have previously shown that the main source of arachidonate in thrombin-stimulated human platelets is 1-acyl-2-arachidonoyl (AA) glycerophosphocholine (GPC) and release of 3H-AA from this phospholipid also was correlated with increased 3H-AA in ether phospholipid. This ATP independent transfer of 3H-AA from 1,2 diacyl GPC to ether phospholipid (transacylation) also occurs in resting cells. Human platelets in 1/10 volume of plasma (ACD anticoagulant, pH 6.5) were radiolabelled with 3H-AA for 60 min at 37°C and then exogenous 3H-AA was removed by gel filtration into Tyrode's buffer, pH 7.4, 0.2% albumin. These radiolabelled cells were incubated in the absence of exogenous 3H-AA for four hours followed by Bligh and Dyer extraction and thin layer chromatography purification of phospholipids. 3H-AA in 1,2 diacyl GPC was found to decrease by over 20% and increase substantially in 1-0-alkyl-2-acyl GPC and 1-0-alk-1'-enyl-2-acyl glycerophospho ethanolamine (GPE), In this same time interval the mass of AA released by thrombin (5 U/ml, 10 min, 37°C, no stirring)in the presence of BIT 775C and measured by GLC, stayed the same (30 nmoles/109 cells), however, the specific activity decreased. Using reverse phase HPLC to resolve diradylglycerobenzoate derivatives of phospholipids: acylation, deacylation, and transacylation were observed for individual AA-containing molecular species of phospholipid, including those with an unsaturated fatty acid at sn-1. In particular the radiolabellinq of the 1-unsaturate-2-arachidonoyl GPC correlated with the specific activity of the 3H-AA released by stimulation with thrombin. Furthermore, 1-arachidonoyl-2-3H-arachidonoyl GPC was completely deacylated while 50 % of its mass remained. This contrasted with 16:0, and 18:0-2-arachidonoyl GPC in which the specific activity remained the same before and after deacylation. We conclude that deacylation of AA-containing molecular species of 1,2 diacyl GPC in stimulated cells includes molecular species which are also a source of arachidonic acid for transacylation reactions.
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Steedle, Jeffrey. "Decomposing GPA: Why Is High School GPA the Best Single Predictor of First-Year GPA?" In 2020 AERA Annual Meeting. Washington DC: AERA, 2020. http://dx.doi.org/10.3102/1569408.

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Kaiser, Ralf, Donald G. Crabb, Yelena Prok, Matt Poelker, Simonetta Liuti, Donal B. Day, and Xiaochao Zheng. "Future GPD Measurements." In SPIN PHYSICS: 18th International Spin Physics Symposium. AIP, 2009. http://dx.doi.org/10.1063/1.3215714.

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Nio, Tomomi, Toshiaki Takeshima, Mitsuhiko Fuda, Yoko Fujita, Norio Saito, and Toshiyuki Konishi. "JAXA GPM mission operation system overview and GPM data distribution." In IGARSS 2014 - 2014 IEEE International Geoscience and Remote Sensing Symposium. IEEE, 2014. http://dx.doi.org/10.1109/igarss.2014.6947298.

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Wilheit, Thomas, Wesley Berg, Hamideh Ebrahimi, Rachael Kroodsma, Darren McKague, Vivienne Payne, and James Wang. "Intercalibrating the GPM constellation using the GPM Microwave Imager (GMI)." In IGARSS 2015 - 2015 IEEE International Geoscience and Remote Sensing Symposium. IEEE, 2015. http://dx.doi.org/10.1109/igarss.2015.7326996.

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Reports on the topic "GP9"

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Cook, Samantha, Marissa Torres, Nathan Lamie, Lee Perren, Scott Slone, and Bonnie Jones. Automated ground-penetrating-radar post-processing software in R programming. Engineer Research and Development Center (U.S.), September 2022. http://dx.doi.org/10.21079/11681/45621.

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Ground-penetrating radar (GPR) is a nondestructive geophysical technique used to create images of the subsurface. A major limitation of GPR is that a subject matter expert (SME) needs to post-process and interpret the data, limiting the technique’s use. Post-processing is time-intensive and, for detailed processing, requires proprietary software. The goal of this study is to develop automated GPR post-processing software, compatible with Geophysical Survey Systems, Inc. (GSSI) data, in open-source R programming. This would eliminate the need for an SME to process GPR data, remove proprietary software dependencies, and render GPR more accessible. This study collected GPR profiles by using a GSSI SIR4000 control unit, a 100 MHz antenna, and a Trimble GPS. A standardized method for post-processing data was then established, which includes static data removal, time-zero correction, distance normalization, data filtering, and stacking. These steps were scripted and automated in R programming, excluding data filtering, which was used from an existing package, RGPR. The study compared profiles processed using GSSI software to profiles processed using the R script developed here to ensure comparable functionality and output. While an SME is currently still necessary for interpretations, this script eliminates the need for one to post-process GSSI GPR data.
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Ray, Laura, Madeleine Jordan, Steven Arcone, Lynn Kaluzienski, Benjamin Walker, Peter Ortquist Koons, James Lever, and Gordon Hamilton. Velocity field in the McMurdo shear zone from annual ground penetrating radar imaging and crevasse matching. Engineer Research and Development Center (U.S.), December 2021. http://dx.doi.org/10.21079/11681/42623.

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The McMurdo shear zone (MSZ) is strip of heavily crevassed ice oriented in the south-north direction and moving northward. Previous airborne surveys revealed a chaotic crevasse structure superimposed on a set of expected crevasse orientations at 45 degrees to the south-north flow (due to shear stress mechanisms). The dynamics that produced this chaotic structure are poorly understood. Our purpose is to present our field methodology and provide field data that will enable validation of models of the MSZ evolution, and here, we present a method for deriving a local velocity field from ground penetrating radar (GPR) data towards that end. Maps of near-surface crevasses were derived from two annual GPR surveys of a 28 km² region of the MSZ using Eulerian sampling. Our robot-towed and GPS navigated GPR enabled a dense survey grid, with transects of the shear zone at 50 m spacing. Each survey comprised multiple crossings of long (> 1 km) crevasses that appear in echelon on the western and eastern boundaries of the shear zone, as well as two or more crossings of shorter crevasses in the more chaotic zone between the western and eastern boundaries. From these maps, we derived a local velocity field based on the year-to-year movement of the same crevasses. Our velocity field varies significantly from fields previously established using remote sensing and provides more detail than one concurrently derived from a 29-station GPS network. Rather than a simple velocity gradient expected for crevasses oriented approximately 45 degrees to flow direction, we find constant velocity contours oriented diagonally across the shear zone with a wavy fine structure. Although our survey is based on near-surface crevasses, similar crevassing found in marine ice at 160 m depth leads us to conclude that this surface velocity field may hold through the body of meteoric and marine ice. Our success with robot-towed GPR with GPS navigation suggests we may greatly increase our survey areas.
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Cable, W., and J. Boike. GPS interferometric reflectometry (GPS-IR). Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 2019. http://dx.doi.org/10.4095/321046.

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Lever, James, Allan Delaney, Laura Ray, E. Trautman, Lynette Barna, and Amy Burzynski. Autonomous GPR surveys using the polar rover Yeti. Engineer Research and Development Center (U.S.), March 2022. http://dx.doi.org/10.21079/11681/43600.

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The National Science Foundation operates stations on the ice sheets of Antarctica and Greenland to investigate Earth’s climate history, life in extreme environments, and the evolution of the cosmos. Understandably, logistics costs predominate budgets due to the remote locations and harsh environments involved. Currently, manual ground-penetrating radar (GPR) surveys must preceed vehicle travel across polar ice sheets to detect subsurface crevasses or other voids. This exposes the crew to the risks of undetected hazards. We have developed an autonomous rover, Yeti, specifically to conduct GPR surveys across polar ice sheets. It is a simple four-wheel-drive, battery-powered vehicle that executes autonomous surveys via GPS waypoint following. We describe here three recent Yeti deployments, two in Antarctica and one in Greenland. Our key objective was to demonstrate the operational value of a rover to locate subsurface hazards. Yeti operated reliably at −30 ◦C, and it has good oversnow mobility and adequate GPS accuracy for waypoint-following and hazard georeferencing. It has acquired data on hundreds of crevasse encounters to improve our understanding of heavily crevassed traverse routes and to develop automated crevasse-detection algorithms. Importantly, it helped to locate a previously undetected buried building at the South Pole. Yeti can improve safety by decoupling survey personnel from the consequences of undetected hazards. It also enables higher-quality systematic surveys to improve hazard-detection probabilities, increase assessment confidence, and build datasets to understand the evolution of these regions. Yeti has demonstrated that autonomous vehicles have great potential to improve the safety and efficiency of polar logistics.
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Brown, Alison, Randy Silva, and Ed Powers. High-Gain Advanced GPS Receiver for Precision GPS Applications. Fort Belvoir, VA: Defense Technical Information Center, May 2000. http://dx.doi.org/10.21236/ada475831.

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Caton, Ronald G., Michael J. Kendra, and William J. McNell. GPS Scintillation Analysis. Fort Belvoir, VA: Defense Technical Information Center, January 1998. http://dx.doi.org/10.21236/ada346074.

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Behrend, Dirk. GPS Activities at SLAC. Office of Scientific and Technical Information (OSTI), November 2002. http://dx.doi.org/10.2172/808669.

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Long, Alex Roberts. Jayenne GPU Strategy Update. Office of Scientific and Technical Information (OSTI), May 2020. http://dx.doi.org/10.2172/1634935.

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Axelrad, Penina. GPS Based Attitude Determination. Fort Belvoir, VA: Defense Technical Information Center, December 1995. http://dx.doi.org/10.21236/ada327730.

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Counselman, C. C. Origins of GPS Surveying. Fort Belvoir, VA: Defense Technical Information Center, April 1991. http://dx.doi.org/10.21236/ada239676.

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