Dissertations / Theses on the topic 'Golden'
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Verma, Pooja. "Golden Circle." Thesis, California State University, Long Beach, 2018. http://pqdtopen.proquest.com/#viewpdf?dispub=10638738.
Full textDue to the mounting rate of patients suffering from PTSD starting at a young age, there have been many studies and guidelines to help improve the conditions of these patients. Though there are many hospitals focusing on treatment of patients suffering from mental diseases, none of these hospitals or clinics concentrate on the welfare of the children suffering from PTSD specifically. The business plan discussed here addresses this concern. It is a healing center “Golden Circle” providing care and treatment to young adults aged between 13–25 years suffering from PTSD especially after road traffic accidents located in Los Angeles County. Golden Circle business plan is proposed to help identify the market trends and areas of concern by studying the company analysis, market potential and demand, competitor analysis, customer analysis, marketing strategy, feasibility and SWOT analysis, legal and regulatory issues and finally the financial analysis. Golden Circle is anticipated to help the society as well as generate good profit.
Topinka, Jiří. "Golden disc." Master's thesis, Vysoké učení technické v Brně. Fakulta výtvarných umění, 2014. http://www.nusl.cz/ntk/nusl-232430.
Full textSneed, Mark R. "Qoheleth's "golden mean"." Theological Research Exchange Network (TREN), 1986. http://www.tren.com.
Full textWeinberg, Danielle E. "The Golden Record." Digital Commons at Loyola Marymount University and Loyola Law School, 2014. https://digitalcommons.lmu.edu/etd/48.
Full textRabinovich, Daniel. "Chemical golden anniversary." Revista de Química, 2017. http://repositorio.pucp.edu.pe/index/handle/123456789/123960.
Full textChemical golden anniversary: as tribute to the PUCP's chemical section for its 50 years of work this essay features stamps with gold-related pictures
Draper, Michael. "Golden liquid crystal nanoparticles." Thesis, University of York, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.542804.
Full textMlčoch, Tomáš. "Economics of Golden Crime." Master's thesis, Vysoká škola ekonomická v Praze, 2013. http://www.nusl.cz/ntk/nusl-199295.
Full textBlom, Lucas, and Johanna Stenbäck. "The golden ratio - still golden? A research of the gold ratio in digital formats." Thesis, Linköpings universitet, Medie- och Informationsteknik, 2015. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-121676.
Full textPetzrick, Ernest Paul. "Currents through the Golden Gate." Thesis, Monterey, California. Naval Postgraduate School, 1993. http://hdl.handle.net/10945/26442.
Full textPaul, Sara R. "Stories from a Golden State." ScholarWorks@UNO, 2013. http://scholarworks.uno.edu/td/1772.
Full textDunn, Jessica. "Golden Handshakes at Commercial Banks." OpenSIUC, 2013. https://opensiuc.lib.siu.edu/dissertations/671.
Full textHagström, Anna. "From The Golden Compass to The Golden Compass : a narratological study of novel and film adaptation." Thesis, Högskolan i Gävle, Akademin för utbildning och ekonomi, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:hig:diva-9483.
Full textYu, Dmytruk A. "PHILOSOPHICAL MEANING OF THE GOLDEN SECTION." Thesis, Національний авіаційний університет, 2017. http://er.nau.edu.ua/handle/NAU/28072.
Full textLowy, Elliott. "The evolution of the golden rule /." Thesis, Connect to this title online; UW restricted, 1997. http://hdl.handle.net/1773/9017.
Full textKent, Thomas Emmett. "New investigations into golden shiner culture." [Ames, Iowa : Iowa State University], 2009.
Find full textEngström, Linda, and Malin Heder. "Golden Ratio : Utformning av en ny filterbryggare." Thesis, Karlstads universitet, Fakulteten för teknik- och naturvetenskap, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:kau:diva-8061.
Full textUnder vårterminen 2011 har Linda Engström och Malin Heder självständigt genomfört “Golden Ratio”, ett examensarbete som omfattat 22,5 hp. Examensarbetet har följt kursplanen för Examensarbete för högskoleingenjörsexamen i innovationsteknik och design (MSGC12) vilket var en kurs i Innovations- och designingenjörsprogrammet inom Fakulteten för teknik och naturvetenskap vid Karlstads universitet. Uppdragsgivare har varit Crem International AB, verksamt i Åmotfors. Företaget utvecklar, tillverkar och marknadsför bland annat kaffemaskiner. Handledare vid företaget var Peter Larsson och handledare vid Karlstads universitet var Monica Jakobsson. Examinator för examensarbetet var Fredrik Thuvander, professor inom Fakulteten för teknik- och naturvetenskap vid Karlstads universitet. Ett patent, som Crem International AB skapat, innebar en ny teknik för att effektivisera och minimera energiåtgången vid kaffeberedning samtidigt som det ger en bra kaffekvalitet. Företaget hade för avsikt att integrera denna teknik i en filterbryggare och strävar efter att det sker i en ny utformning som skiljer sig från den traditionella formen på filterbryggare. Detta kom att föranleda projektet. Vid överlämningen av uppdraget existerade den framtida filterbryggaren endast som en vision kallad ”Golden Ratio”, engelska motsvarigheten för “Det gyllene snittet”. Ett särskilt fokus i projektet har varit att ta fram ett så grundläggande researchmaterial som möjligt. Detta för att frambringa en form som avspeglar de behov som fanns hos användarna samt de krav och önskemål som eftersträvas på marknaden. Projektets researchfas har därför bestått av en redogörande marknadsundersökning innehållande flera intervjuer, observationer och analyser med professionella användare, experter inom kaffesegmentet samt tillverkare av kaffemaskiner. Genom flera idégenereringsmetoder och med hjälp av olika fokusgrupper samt egna reflektioner kom gruppen fram till sex konkreta koncept för innovativ utformning av en framtida filterbryggare. Utifrån dessa sex koncept användes tre utvärderingsmatriser för att på ett kvalitativt sätt evaluera fram till den mest relevanta lösningen i samråd med handledaren på företaget. Det slutgiltiga konceptvalet bestod i en kombination av flera koncept. Konceptvalet innebar en flexibel samt sober och minimalistisk lösning genom att den kunde anpassas utefter behovet av utrymme. Konceptvalet bestod av en beredningsmaskin med samhörande kran som visualiserade det färdigbryggda kaffet. Under konceptutvecklingsfasen koncentrerades arbetet mot att visualisera det valda konceptet genom CAD-modellering, presentationsmodell och grafiska illustrationer. Konceptvalet innefattade ett förslag på utformning av en framtida filterbryggare samt ett förslag på material- och färgval. Genom den framtagna tilläggslistan för konceptet påvisade även gruppen fler möjligheter för vidareutveckling.
Nelson, Megan Jane. "Francis Turner Palgrave and The golden treasury." Thesis, University of British Columbia, 1985. http://hdl.handle.net/2429/25947.
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English, Department of
Graduate
Johnson, Hilary Grace. "Factors affecting weaning in the golden hamster." Thesis, University of Cambridge, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317744.
Full textPetty, I. T. D. "Gene expression of tomato golden mosaic virus." Thesis, Imperial College London, 1987. http://hdl.handle.net/10044/1/47648.
Full textVales, Marcela. "The Golden Ring: A Narrative Film Production." ScholarWorks@UNO, 2005. http://scholarworks.uno.edu/td/285.
Full textBourque, Danny. "The Toaster That Toasted The Golden Toast." ScholarWorks@UNO, 2008. http://scholarworks.uno.edu/td/707.
Full textJohansson, Maya. "Modelling habitat suitability index for golden eagle." Thesis, Stockholms universitet, Institutionen för naturgeografi, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-197086.
Full textLakhdari-Benalioua, Fadila. "D. H. Lawrence, lecteur du "Golden bough"." Aix-Marseille 1, 1987. http://www.theses.fr/1987AIX10086.
Full textA general introduction to such new fields as anthropology, ethnology and ethnography, to james george frazer and to the controlling ideas of the golden bough includes the preliminary aspects one needs to be familiar with before getting into a detailed discussion on the impact of the golden bough on d. H. Lawrence's selected works. Lawrence has certainly been very deeply affected by his reading of the golden bough. The basic myths, the rites, the legends, the customs and beliefs which constitute the framework of the golden bough have undoubtedly contributed to the shaping of lawrence's imaginative vision of the world. The most important myth is that of the dying and reviving god with its rituals of death and rebirth celebrated every year and closely related to the recurrent rhythm of the seasons. Such a myth, which emphasizes the cyclic conception of the universe and the interrelation of man and the world of nature will help lawrence illustrate his own vision of the world
Weidner, Derek Edward. "Golden Ratio House: A Construction of Form." Thesis, Virginia Tech, 2012. http://hdl.handle.net/10919/32091.
Full textMaster of Architecture
Chai, WeFen Florence. "Golden parachutes, Tobin's Q, and shareholder wealth." The Ohio State University, 1991. http://rave.ohiolink.edu/etdc/view?acc_num=osu1280250249.
Full textMitsuhashi, Gonzalez Kay M. "Bruising profile of fresh 'Golden Delicious' apples." Pullman, Wash. : Washington State University, 2009. http://www.dissertations.wsu.edu/Dissertations/Spring2009/k_mitsuhashi-gonzalez_043009.pdf.
Full textTitle from PDF title page (viewed on June 19, 2009). "Department of Horticulture and Landscape Architecture." Includes bibliographical references.
CASTRO, Ana Cecília Ribeiro de. "Deficiência de macronutrientes em helicônia "Golden Torch"." Universidade Federal Rural de Pernambuco, 2007. http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/4758.
Full textMade available in DSpace on 2016-06-15T15:14:54Z (GMT). No. of bitstreams: 1 Ana Cecilia Ribeiro de Castro.pdf: 1325909 bytes, checksum: 2a37e84a4a4736120bd0856f109fd038 (MD5) Previous issue date: 2007-02-27
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior - CAPES
In order to describe Heliconia psittacorum x Heliconia spathocircinata ‘Golden Torch’ nutritional deficiency symptoms, evaluate macronutrients omission effects on growth, first flower stem characteristics and longevity, greenhouse experiments were conducted under the lacking element technique. The lacking macronutrients treatment reduced growth, shoot tillering and dry weight production compared to the complete nutrient solution treatment. Nutrient symptons occurred as follows: N,K, P, Mg and S. Deficiency symptoms were general chlorosis at – N treatment; slight chlorosis at – P and – S; dark green leaves and necrosis at – K; border chlorosis and necrosis at – Mg. The lack of Ca did not show any visual symptoms.The omission of each macronutrient in the nutritive solution reduced its respective concentration in the plant. Among the evaluated leaves, the concentration tended to a greater reduction in the third leaf. Based on the third leaf macronutrients contents on g kg-1 at the first emitted shoot, the following values were found for complete solution treatment and lacking nutrients treatments, respectively: N =16,28 e 7.87; P = 1,49 e 0, 68; K = 32,68 e 3,26; Ca = 8,76 e 3,38; Mg = 1,75 e 0.70; S = 6,00 e 1,82, at 90 days e N = 24,40 e 5,32; P = 1,32 e 0,46; K = 12,88 e 3,50; Ca = 4,58 e 0,97; Mg = 0,98 e 0,62; S = 4,44 e 1,00, at blooming period. The Heliconia psittacorum x H. spathocircinata ‘Golden Torch’ inflorescence produced under N omission showed a pale orange color and floral stem deformation. N, P and K omission affected stem length, stem diameter, inflorescence length and postharvest longevity, which are considered to be important market characteristics. Macronutrients deficiency reduced floral stem production. Greater postharvest longevity is to be found at higher floral stem dry matter. Carbohydrate ratio in underground parts has positive correlation with floral stem dry matter.
Com o objetivo de descrever os sintomas de deficiências nutricionais, avaliar o efeito da omissão de macronutrientes no crescimento, características da primeira haste floral e longevidade pós-colheita de Heliconia psittacorum x Heliconia spathocircinata cultivar Golden Torch foram conduzidos experimentos em casa de vegetação, mediante técnica do elemento faltante. Os sintomas de deficiência surgiram na seguinte ordem de ocorrência: N, K, P, Mg e S. Os sintomas foram: clorose generalizada em – N; clorose em – P e em – S; folhas verde-escuras e necrose em – K e; clorose ao longo dos bordos com necrose em – Mg. A omissão de Ca não acarretou sintomas visíveis. As omissões dos macronutrientes reduziram o crescimento, perfilhamento e produção de massa seca nas folhas e parte subterrânea das plantas quando comparadas as do tratamento completo. A omissão de cada macronutriente na solução nutritiva ocasionou a redução do seu respectivo teor na planta. Entre as folhas avaliadas, houve tendência à redução destes teores de forma mais acentuada na 3ª folha. Com base nos teores em g kg-1 dos macronutrientes na 3ª folha do primeiro perfilho emitido, encontraram-se os seguintes valores nos tratamentos completo e com omissão, respectivamente:N = 16,28 e 7.87; P = 1,49 e 0, 68; K = 32,68 e 3,26; Ca = 8,76 e 3,38; Mg = 1,75 e 0.70; S = 6,00 e 1,82, na fase vegetativa e N = 24,40 e 5,32; P = 1,32 e 0,46; K = 12,88 e 3,50; Ca = 4,58 e 0,97; Mg = 0,98 e 0,62; S = 4,44 e 1,00, na floração. A omissão de N, P e K reduziram o comprimento e o diâmetro da haste, bem como, o comprimento e longevidade pós-colheita da inflorescência características importantes para comercialização. As inflorescências produzidas no tratamento com omissão de N apresentaram coloração laranja pálido e deformação nas hastes florais. As deficiências de macronutrientes diminuiram, ainda, a produção de hastes florais. Foi observada uma maior durabilidade pós-colheita em Hastesflorais com maior massa seca e diâmetro. O teor de carboidrato na parte subterrânea teve correlação positiva com a massa seca encontrada na haste floral.
Van, Dongen Wouter Frederik Dirk. "Evolutionary ecology of multiple ornaments in the golden whistler /." Connect to thesis, 2005. http://repository.unimelb.edu.au/10187/2243.
Full textMilikic, Biljana. "The Golden Notebook : A feminist novel or not?" Thesis, Växjö University, School of Humanities, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:vxu:diva-5657.
Full textAbstract
The paper will first of all begin with an introduction where the thesis of the paper will be developed and accounted for. Secondly and before the main analysis begins, a brief explanation about feminism will be clarified in a chapter divided into two sections, one dealing with the history and background of the term while the other section describes the different definitions of the term which hopefully will clarify the meaning if it was not familiar to the reader earlier. Since the term feminism is an important part of this paper, I believe that this chapter is of big importance and as soon as the term is clarified for the reader, it will consequently help the reader to understand the rest of the paper. Especially the section that deals whit the question: what characterizes a feminist novel, since there are similarities and connections between the term feminism and a feminist novel. By understanding the meaning of the term one consequently also gets a clue what a feminist novel can be about.
So therefore it is also necessary to explain the characterizations of a feminist novel, to be able to argue that this novel is feminist as well. Despite the fact that there are hardly any references to critics that ‘define’ a feminist work of art, there are still plenty of praised works that are regarded as feminist. By comparing these praised feminist works with The Golden Notebook it will help to show that this novel is just as feminist as the others. Secondly a section where a short summary of the novel will be accounted for, so the reader can get a little hint of what the novel is all about. Then the actual analysis will follow where the statement will be proved; that the Golden Notebook really is a feminist novel by dividing the arguments into two main sections, one called Family and Home and the other called Love and Relationship where arguments related to these two subjects will be used.
Houet, Jérémie. "Les golden shares en droit de l'Union européenne." Thesis, Paris 10, 2014. http://www.theses.fr/2014PA100072.
Full textIn the currrent context of financial crisis, the recourse of Member States to golden shares reveals the ongoing movement to protect domestic firms against foreign investors. This mechanism however falls within the scope of EU norms. From the application of these rules emerges an autonomous legal framework which submit this particular ownership regime of Member States to comply with the free movement of capital and freedom of establishment. If golden shares are not prohibited per se, the strict control undertaken by both the Commission and the Court of Justice only leaves a limited marge de manoeuvre to Member States in the use of such device.This control has a dual incidence. Firstly, it allows to point out some inconsistencies that such analysis could generated in EU law. To that extent, calling into question the elements of the legal framework may be relevant. Secondly, it reveals the limits of the constitution of a truly internal market. Member States are likely to restore the golden shares mechanism by devious means. Their attempts reveal a deeper malaise, the fear of foreign investment in domestic companies operating in strategic sectors. This questions the opportunity of a common instrument to control foreign investment. Response to the crisis must be taken at the level of the European Union, and not anymore at Member States’
Bitel, Anton. "Quis ille? : alter egos in Apuleius' 'Golden Ass'." Thesis, University of Oxford, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.365762.
Full textWhittingham, Mark Jonathan. "Habitat requirements of breeding golden plover Pluvialis apricaria." Thesis, University of Sunderland, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.319743.
Full textKraus, Richard (Richard A. ). "The Golden Lariat : explaining American aid to Israel." Thesis, Massachusetts Institute of Technology, 2009. http://hdl.handle.net/1721.1/54610.
Full textCataloged from PDF version of thesis.
Includes bibliographical references (p. 181-186).
An observational study was conducted to determine the most likely explanation of American support for Israel. Several extant hypotheses were considered, most particularly, and at greatest length, that of a pro-Israel domestic lobby in the United States, but also that it had to do with Cold War containment, common values, or precedent. It was ultimately concluded that the domestic lobby hypothesis could not account for American support, since the level of that support correlated negatively with the resources of the lobby, and because sudden, temporary changes in the level of American support did not coincide with any similar changes in the resources of the lobby. Furthermore, statistical analysis indicated that there was on balance no benefit for politicians who supported the lobby's agenda, and no cost for those who opposed it. Likewise, the other explanations also proved unsatisfactory. The containment hypothesis, for instance, could not explain why American support continued after the Cold War ended, while the common values hypothesis could not explain why American support did not begin until 1971, nor why it peaked in 1979 and began to decline in the eighties. Finally, it was concluded that the best explanation of American support was that it gave the United States the leverage to restrain Israeli belligerence, for which the United States was blamed by the Arab states. In this way, the U.S. was able to minimize damage to its relations with the Arabs resulting from the Arab-Israeli conflict.
by Richard Kraus.
S.M.
Redmond, Walter. "Being, Science and Logic in the Golden Age." Pontificia Universidad Católica del Perú - Departamento de Humanidades, 2013. http://repositorio.pucp.edu.pe/index/handle/123456789/112818.
Full textEn los siglos XVI y XVII los lógicos hispanos e hispanoamericanos trabajaron con una compleja teoría de los tipos para explicar las diversas clases de entidades denotadas o significadas en el lenguaje. A. de la Vera Cruz y sus colegas plantearon un sistema lógico de muchas clases donde las sentencias generales eran reducibles a hileras de entidades cuyos términos referían a cosas singulares, el mismo que les permitió un análisis semántico básico. A. Rubio,asimismo, desarrolló una teoría del lenguaje científico y la aplicó a la lógica misma, definiendo las proposiciones de la lógica como atribuciones de un segundo orden mental, propiedades relativas a contenidos de primer orden, atribuibles ellos mismos a objetos singulares.
Blankenship, Ryan A. "The Golden Ratio and Fibonacci Sequence in Music." Ohio Dominican University Honors Theses / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=oduhonors1620086748612102.
Full textSoto, Audrey. "Le golden parachute, une technique en quête d'identité." Paris 12, 2005. http://www.theses.fr/2005PA122001.
Full textComing from the English-speaking countries, the notion of golden parachute has always let perplexed the lawmaker who has never consecrate it in our law. Used by some french companies since ten years ago, the golden parachute has never been enclosed by some definite rules. Consequently, we should give a real definition. Often used as a bait in order to attract in the company, the high potentials, the golden parachute has always let to indemnify the manager or an important executive who stops his functions. With his changeable nature, the golden parachute stays an useful that the French law has difficulty to study, that's why we are going to temp to throw light on the outlines. As it should be demonstrated throughout the thesis, the legal nature of the golden parachute is changeable and it makes things difficult to determine the procedure. His legalization will bring certainly some coherence in his legal nature and his procedure
Kabirian, Alireza. "Continuous optimization via simulation using Golden Region search." [Ames, Iowa : Iowa State University], 2009.
Find full textThom, Johan C. "The Pythagorean "Golden verses" : with introduction and commentary /." Leiden : E. J. Brill, 1995. http://catalogue.bnf.fr/ark:/12148/cb35722330x.
Full textSrenk, Petr. "Genetische Grundlagen der Idiopathischen Epilepsie beim Golden Retriever /." [S.l : s.n.], 1994. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.
Full textSakai, Ai, Akihiko Kaneko, and Mitsuyoshi Yanagihara. "Golden Rule, Non-distortional Tax and Governmental Transfer." 名古屋大学大学院経済学研究科附属国際経済政策研究センター, 2013. http://hdl.handle.net/2237/19236.
Full textBurner, Colleen. "Sister Golden Calf: Stories, Dissections, & A Novella." PDXScholar, 2014. https://pdxscholar.library.pdx.edu/open_access_etds/2081.
Full textNewnam, John Calvin. "Habitat use by the golden-cheeked warbler in Texas." [College Station, Tex. : Texas A&M University, 2008. http://hdl.handle.net/1969.1/ETD-TAMU-3263.
Full textGivel, Reto. "Taming Glaucon through instrumental rationality to the Golden Rule /." Bern : R. Givel, 2006. http://www.ub.unibe.ch/content/bibliotheken_sammlungen/sondersammlungen/dissen_bestellformular/index_ger.html.
Full textHo, Chun-sing. "Redevelopment of the Golden Centre at Sham Shui Po." Click to view the E-thesis via HKUTO, 1997. http://sunzi.lib.hku.hk/hkuto/record/B31983303.
Full textIncludes special report study entitled : Spatail [sic] quality for social interaction. Includes bibliographical references. Also available in print.
Torstensson, Camilla. "Writer's Block in The Golden Notebook : Cause and Solution." Thesis, Linnéuniversitetet, Institutionen för språk och litteratur, SOL, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-13587.
Full textHildingsson, Karin. "Golden Lane Estate : A Real Part of the City." Thesis, KTH, Arkitektur, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-30475.
Full textMcDonald, Bonny. "Buried Alive: Hard Science Fiction Since the Golden Age." TopSCHOLAR®, 2005. http://digitalcommons.wku.edu/theses/461.
Full textMiyazato, Ligia Gomes [UNESP]. "Histopatologia e imunoistoquímica na distrofia muscular do Golden Retriever." Universidade Estadual Paulista (UNESP), 2010. http://hdl.handle.net/11449/104640.
Full textCoordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)
Fatec
O objetivo deste estudo foi o de caracterizar lesões musculares em cães com Distrofia Muscular do golden retriever (DMGR), de diferentes idades, por análises histopatológica e imunoistoquímica. Foram utilizados vinte e cinco cães machos classificados e distribuídos em grupos de acordo com a idade: grupo I – distróficos até 1 ano; grupo II – distróficos acima de 1 ano; grupo III - controle até 1 ano; grupo IV - controle acima de 1 ano. Uma amostra de cada músculo foi fixada em solução de formol, processadas pelas técnicas usuais de inclusão em parafina, coradas com HE e TGM para análise histopatológica e processadas para a análise imunoistoquímica de linfócitos T-CD3+, antígeno MHC II e vimentina. Outras amostras foram congeladas em nitrogênio líquido e processadas pelas técnicas usuais para realização das reações imunoistoquímicas para marcação dos linfócitos T-CD4+, TCD8+ e do antígeno MHC I. Os resultados mostraram que as lesões nos músculos distróficos do grupo I foram moderadas comparativamente às do grupo II que foram severas. Nos músculos distróficos, os linfócitos T-CD3+, T-CD4+ e T-CD8+ concentravam-se nas áreas de degeneração e necrose. O número de linfócitos T-CD3+ e T-CD4+ foi significativamente maior (p < 0.05) em todos os músculos distróficos em comparação aos controles, demonstrando a participação dos linfócitos T na doença. O número de linfócitos T-CD8+ foi significativamente maior (p < 0.05) nos distróficos, exceto para os músculos sartório cranial no grupo I, diafragma e bíceps femoral no grupo II. A imunoexpressão do MHC I intensificou-se com a idade nos animais distróficos, ao contrário do MHC II que se manteve. A imunoexpressão da vimentina e do VEGF nos músculos distróficos foi discreta (escore 1) em todos os músculos avaliados. Destes resultados podemos...
The purpose of this study was to characterize the lesions in dystrophic muscles of DMGR dogs of different ages, by means of histopathological and immunohistochemistry analysis. Twenty-five male dogs were classified and distributed into groups according to the age: Group I - dystrophic up to 1 year, group II - dystrophic over 1 year, group III - control up to 1 year, group IV - control over 1 year. One sample from each muscle was fixed in formalin solution, processed by usual techniques of paraffin embedding, stained with HE and TGM for histopathological purposes and processed for immunohistochemical analysis of the distribution of T-lymphocytes CD3+, MHC II and vimentin. Other samples were frozen in liquid nitrogen, processed by usual techniques of freezing in order to perform the techniques of immunohistochemical labelling for CD4+ T-lymphocytes, T-CD8+ and MHC I. The results of histopathological analysis showed that the lesions in dystrophic muscles in the Group I were moderate compared to that ones in the Group II which were severe. The CD3+, CD4+ and CD8+ Tlymphocytes were more numerous in dystrophic muscles especially in areas of degeneration and necrosis. The number of CD3+ and CD4+ T-lymphocytes was found to be significantly higher (p <0.05) in all dystrophic muscles compared to controls demonstrating the involvement of T-lymphocytes in the disease. The number of CD8+ Tlymphocytes was found to be significantly higher (p <0.05) in dystrophics, except for the cranial sartorius muscles in the Group I and the diaphragm and biceps femoris in the Group II. The immunoexpression of MHC I increased with age in dystrophic animals, in contrast to MHC II that remained the same. The immunoexpression of vimentin and VEGF in the dystrophic muscles was mild (score 1) upon all muscles. From these results we can conclude that in dystrophic muscle immunoexpression of... (Complete abstract click electronic access below)
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