Journal articles on the topic 'Ginger (Zingiber officinale Canton)'

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1

Kala, Chandra, Syed Salman Ali, and Sudhir Chaudhary. "COMPARATIVE PHARMACOGNOSTICAL EVALUATION OF COSTUS SPECIOSUS (WILD GINGER) AND ZINGIBER OFFICINALE (GINGER) RHIZOME." International Journal of Current Pharmaceutical Research 8, no. 4 (October 18, 2016): 19. http://dx.doi.org/10.22159/ijcpr.2016v8i4.15270.

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Objective: Costus speciosus Koen. (Ginger) is an Indian ornamental plant, belonging to family Costaceae. The present research work deals with the establishment of standardization parameter regarding comparative pharmacognostic study between Costus speciosus and Zingiber officinale rhizome.Methods: Macroscopic and microscopic evaluation, physicochemical parameters like ash values, moisture content, extractive value, fluorescence analysis and the preliminary phytochemical investigation was done.Results: The Macroscopic difference was found as an absence of odor and taste in Costus speciosus and presence of pungent and aromatic odor in Zingiber officinale. Oil globule, tracheids, starch granules in Zingiber officinale was found whereas the absence of the same in Costus speciosus rhizome was found in the microscopic evaluation. Fluorescence study also exhibits differences. The presence of saponin, carbohydrate, glycosides in Costus speciosus whereas Zingiber officinale revealed the presence of alkaloids, glycosides, flavonoids and protein.Conclusion: These finding can serve as the basis for Identification and investigation of Costus speciosus and Zingiber officinale rhizome and can also establish the characteristic differentiating features of both.
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Suharto, Idola Perdana Sulistyoning, Erik Irham Lutfi, and Mega Diasty Rahayu. "PENGARUH PEMBERIAN JAHE (Zingiber officinale) TERHADAP GLUKOSA DARAH PASIEN DIABETES MELLITUS." Care : Jurnal Ilmiah Ilmu Kesehatan 7, no. 3 (November 4, 2019): 76. http://dx.doi.org/10.33366/jc.v7i3.1363.

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The objective of this study was to analysis effect of giving ginger (Zingiber officinale) to the blood glukose in patients of diabetes mellitus. The method was one group pretest – posttest design. There were 16 patients of diabetes mellitus who was given ginger (Zingiber officinale). Ginger (Zingiber officinale) was given twice a day for a week The dose of ginger is 50 mg of ginger boiled with 200 ml of water Blood glucose was measured before and after ginger administration. The data was analyzed by wilcoxon signed rank test. Based on wilcoxon signed rank test, obtained result that there was a significant difference (α
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3

Shivananjappa, Mahesh. "Cardioprotective effects of ginger (Zingiber officinale)." Southeast Asian Journal of Health Professional 4, no. 1 (February 15, 2022): 1–5. http://dx.doi.org/10.18231/j.sajhp.2021.001.

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Ginger is the rhizome of the plant In ayurveda, it is referred as “vishwabheshaja” which means the universal medicine, can be given to anyone living in this world and it would be suited to all. In addition to its culinary use ginger also possess medicinal property by bioactive components present in them. Ginger can be used in its fresh, dried, powdered, oil and syrup forms. Ginger is an herbal remedy and reported to possess strong anti-diabetic, anti-inflammatory, anti-oxidant, anti-microbial and other activities. The present review is conducted to evaluate cardioprotective effect of ginger. Ginger was found effective in combating cardiovascular disease such as hypertension, obesity, atherosclerosis by changing lipid profile.
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Dianasari, Dewi, Endah Puspitasari, Indah Yulia Ningsih, Bawon Triatmoko, and Fauzia Ken Nasititi. "Potensi Ekstrak Etanol dan Fraksi-Fraksinya Dari Tiga Varietas Jahe Sebagai Agen Antibakteri Terhadap Staphylococcus aureus." Pharmacon: Jurnal Farmasi Indonesia 17, no. 1 (June 30, 2020): 9–16. http://dx.doi.org/10.23917/pharmacon.v17i1.9226.

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One of the natural ingredients that to be used to inhibit bacterial growth is the Zingiber officinale. In Indonesia, there are 3 types of ginger which are distinguished by morphology, namely ‘emprit ginger (Zingiber officinale var. Amarum), ‘ gajah’ ginger (Zingiber officinale var. Officinarum), and red ginger (Zingiber officinale var. Rubrum). This research was conducted to determine the activity of extracts and fractions of three ginger varieties in inhibiting the growth of Staphylococcus aureus using the disc diffusion method. The test group consisted of ethanol extract, n-hexane fraction, and ethyl acetate fraction from 3 ginger varieties, concentrations of 5, 10, 20% w / v, gentamicin 10 μg (positive control) and 10% DMSO (negative control). The test results showed that ethanol extracts and fractions from the rhizomes of three varieties of ginger have the ability to inhibit S. aureus at concentrations of 5, 10, and 20% w / v, increasing the concentration will increase the diameter of the inhibition zone. At a concentration of 20% of all samples, the one with the greatest resistance was the n-hexane fraction (diameter of inhibitory zone of emprit ginger 9.80 mm, elephant ginger 9.78 mm, and red ginger 9.90 mm). The difference in ginger variety only affects the antibacterial activity of the ethanol extract, but not the n-hexane and ethyl acetate fractions.
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5

Hoque, MA, BK Bala, MA Hossain, and M. Borhan Uddin. "Drying Kinetics Of Ginger Rhizome (Zingiber officinale)." Bangladesh Journal of Agricultural Research 38, no. 2 (July 28, 2013): 301–19. http://dx.doi.org/10.3329/bjar.v38i2.15892.

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This paper presents the drying kinetics of ginger rhizome under blanched and nonblanched conditions using hybrid solar dryer and mechanical tray dryer at three temperature levels. The drying rate increases with the increase in drying air temperature and blanching also increases the drying rate. The drying rate depends on shape and size of the ginger rhizomes. The highest drying rate was found for sliced samples of ginger rhizome followed by splitted and whole root samples. Five thin layer drying models were fitted to the experimental data of blanched and sliced ginger rhizomes. The Page equation was found to be the best to predict the moisture content of sliced ginger rhizome in thin layer. The agreement between the predicted and experimental results was excellent. Colour of ginger rhizomes was slightly changed after drying. Lightness of ginger rhizomes decreased with an increase in drying temperature for all samples except sliced and blanched samples. For drying of ginger rhizome, it should be sliced and blanched and dried below 70°C for better quality dried products. Bangladesh J. Agril. Res. 38(2): 301-319, June 2013 DOI: http://dx.doi.org/10.3329/bjar.v38i2.15892
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6

Indrayani, Ferna, and Nurul Hikma. "The Formulation and Stability Test of The Balm Emprit Ginger (Zingiber officinale var. amarum) Essential Oil." Indonesian Journal of Pharmaceutical Education 2, no. 2 (September 3, 2022): 208–17. http://dx.doi.org/10.37311/ijpe.v2i3.15863.

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Emprit ginger (Zingiber officinale var. amarum) is a rhizome plant that is much of the time tracked down in the locale. Tanasitolo, Kab. Wajo. Its utilization is most generally utilized as a cooking zest, defeating joint inflammation, muscle torment, treating colds, treating hacks, as a characteristic cell reinforcement and warming the body. The compound parts contained in emprit ginger (Zingiber officinale var. amarum) are zingiberene, shagaol, sap, and gingerol which are adequate as cancer prevention agents and mitigating or then again reflexology. This study aims to decided how to of ginger emprit (Zingiber officinale var. amarum) as a salve form of a natural balm. This type of research is a direct observation in the laboratory using the distillation method to obtain the essential oil in ginger emprit (Zingiber officinale var. amarum) was then made in the form of a balm with different concentrations of essential oils, namely F1 (0 g), F2 (1.5 g), and F3 (2 g) using accelerated stability testing on the balm preparation, stored for 6 days with 3 cycles (40C and 400C) the observations included organoleptic tests (shape, smell, and colour), homogeneity test, pH test, spreadability test, adhesion test, and specific gravity.. This study indicate that a stable balm preparation that meets the standard requirements based on SNI with accelerated stability testing is formula F3 with a concentration of 2 grams of ginger essential oil. Emprit ginger (Zingiber officinale var. amarum) can be formed in a balm preparation.
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Anderson, T., S. F. du Plessis, Tersia R. Niemand, and A. Scholtz. "EVAPORATIVE COOLING OF GINGER (ZINGIBER OFFICINALE)." Acta Horticulturae, no. 275 (July 1990): 173–80. http://dx.doi.org/10.17660/actahortic.1990.275.18.

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8

Abascal, Kathy, and Eric Yarnell. "Clinical Uses of Zingiber officinale (Ginger)." Alternative and Complementary Therapies 15, no. 5 (October 2009): 231–37. http://dx.doi.org/10.1089/act.2009.15501.

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9

Mascolo, N., R. Jain, S. C. Jain, and F. Capasso. "Ethnopharmacologic investigation of ginger (Zingiber officinale)." Journal of Ethnopharmacology 27, no. 1-2 (November 1989): 129–40. http://dx.doi.org/10.1016/0378-8741(89)90085-8.

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10

Mustafa, T., and K. C. Srivastava. "Ginger (zingiber officinale) in migraine headache." Journal of Ethnopharmacology 29, no. 3 (July 1990): 267–73. http://dx.doi.org/10.1016/0378-8741(90)90037-t.

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11

Srivastava, K. C., and T. Mustafa. "Ginger (Zingiber officinale) and rheumatic disorders." Medical Hypotheses 29, no. 1 (May 1989): 25–28. http://dx.doi.org/10.1016/0306-9877(89)90162-x.

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12

Dian Septinova dan Rr Riyanti, Muhammad Luthfi Hidayat, Ali Husni,. "PENGARUH PERENDAMAN DAGING KAMBING DALAM BLEND JAHE (Zingiber Officinale Roscoe) PADA KONSENTRASI BERBEDA TERHADAP pH, DAYA IKAT AIR DAN SUSUT MASAK." Jurnal Riset dan Inovasi Peternakan (Journal of Research and Innovation of Animals) 3, no. 3 (December 1, 2019): 25–29. http://dx.doi.org/10.23960/jrip.2019.3.3.25-29.

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This study aimed to determine the effect of soaking using ginger blend (Zingiber Officinale Roscoe) as a natural preservative on pH, water holding capacity, and cooking loss of goat meat. The experimental design used was completely randomized design (CRD) with 4 treatments and 5 replications. Goat meat used is thigh part as much as 20 pieces and the ginger used as blend is old ginger. The treatment in this study were P0: goat meat without soaking with blend of ginger, P1: soaked goat meat using a blend of ginger with a concentration of 5%, P2: goat meat soaked using a blend of ginger with a concentration of 10%, and P3: goat meat soaked using blend of ginger with concentration of 20%. The data obtained in this study were analysed with analysis of variance (ANOVA). The results showed that the length of soaking time using ginger blend ( Zingiber Officinale Roscoe) did not significantly affect the physical quality (pH, water holding capacity, cooking loss) of goat meat. Keyword: Concentration, Ginger (Zingiber Officinale Roscoe), pH, Water holding capacity, Cooking loss
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13

KATO, Eishin, Yasuro SUZUKI, Nobutaka SUZUKI, Hoko KYO, and Kazuo UEBABA. "Ingredient Comparison Between Java Ginger ( Zingiber purpureum) and Common Ginger ( Zingiber officinale)." Japanese Journal of Complementary and Alternative Medicine 16, no. 1 (March 31, 2019): 67–69. http://dx.doi.org/10.1625/jcam.16.67.

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14

Harliansyah, Harliansyah, W. N. Wan Zurinah, M. Y. Yasmin Anum, and M. Noor Azian. "Chemopreventive Efficacy of Ginger Extract (Zingiber officinale)." Indonesian Journal of Cancer Chemoprevention 1, no. 2 (June 30, 2010): 118. http://dx.doi.org/10.14499/indonesianjcanchemoprev1iss2pp118-123.

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The liver cells were cultured in the presence of ginger extract at various concentrations (0-1 mg /ml) for 24 h and the cells viability and proliferation rate were evaluated by MTS and BrdU assays, while apoptosis was evaluated by colorimetric determination of caspase 8 and 3 activities. Ginger extract exhibited a dose dependent inhibition of viability and proliferation of WRL-68, HLE and HepG2 cells with IC50 of 569.69 ± 7.99 µg/ml, 389.71 ± 26.56 µg/ml and 358.71 ± 17.12 µg/ml respectively. Ginger extract induced apoptosis through activation of caspase-8 and 3 in a dose dependent pattern for all cells at concentration ranging from 0-500 mg/ml. We found that antiproliferative effect of ginger extract could be associated with induction of apoptosis as shown by increased activities of caspase 8 and 3.The results from this study suggest that ginger extract has chemopreventive properties against hepatoma cells HepG2 and HLE by inhibiting cellular proliferation and inducing apoptosis.Keywords : antiproliferation, apoptosis, caspases, Zingiber officinale
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15

Sardiana, I. Ketut, Tati Budi Kusmiyarti, and Ni Gusti Ketut Roni. "Magnesium Fertilizer Increased Growth, Rhizome Yield, and Essential Oil Content of Ginger (Zingiber officinale) in Organic Field." PLANTA TROPIKA: Jurnal Agrosains (Journal of Agro Science) 10, no. 2 (August 31, 2022): 132–39. http://dx.doi.org/10.18196/pt.v10i2.11406.

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Ginger (Zingiber officinale) is the main biopharmaceutical export commodity of Indonesia. However, its productivity and quality are low because it is not cultivated using optimal techniques. This study aimed to examine the effect of magnesium (Mg) fertilizer on the growth, rhizome yield, and essential oil content of two ginger varieties in the organic field. The two factors tested were the rate of Mg fertilizer application (0, 50, 100, and 150 kg MgOha-1) and the variety of ginger (elephant ginger [Zingiber officinale var. officinarum] and red ginger [Zingiber officinale var. rubrum]). The variables measured were plant height, number of leaves, number of tillers, rhizome weight, and essential oil content. Mg fertilizer application rate and ginger variety significantly affected growth, yield, and essential oil content. No interaction effects were found between the two factors. Mg fertilizer applied at 150 kg MgOha-1 resulted in the highest rhizome yield and essential oil content, with an increase of 21.74% and 15.38%, respectively, compared to the control (0 kg MgOha-1). The yield of elephant ginger was 29.41% higher than that of red ginger, whereas the essential oil content of the red ginger was 16.67% higher than that of the elephant ginger.
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16

Budianto, Andrea, Mulya Dinata, and Endang Isbandiati. "ANTIBACTERIAL ACTIVITIES TEST OF RED GINGER (Zingiber officinale var. rubrum) ETHANOL EXTRACT ON STAPHYLOCOCCUS EPIDERMIDIS." Journal of Widya Medika Junior 4, no. 2 (April 2022): 99–103. http://dx.doi.org/10.33508/jwmj.v4i2.3791.

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Background: Antibiotic is a drug often used against infections caused by bacteria; however, irrational use of antibiotics can cause multidrug resistance (MDR). Staphylococcus epidermidis is a bacteria that has developed an MDR characteristic against antibiotics. Staphylococcus epidermidis is a normal opportunistic flora. Said bacteria can produce a biofilm that enables the bacteria to adhere to prosthetic devices and enter the bloodstream. Red ginger (Zingiber officinale var. rubrum) is a medicinal plant considered antibacterial for its secondary metabolites. Purpose: This study aims to determine the antibacterial effect of red ginger (Zingiber officinale var. rubrum) ethanol extract against Streptococcus epidermidis using a non-equivalent control group design study. Method: Red ginger (Zingiber officinale var. rubrum) ethanol extract was made with the maceration method. This study uses a microdilution test on 96 well plates. The absorbance value was read using a spectrophotometer to determine the Minimum Inhibitory Concentration (MIC) value, and streaking agar was used to find the Minimum Bactericidal Concentration (MBC) value. Result: The result shows that the red ginger (Zingiber officinale var. rubrum) ethanol extract at a concentration of 62,5 μg/mL inhibits 75% of bacteria growth, at 125 μg/mL inhibits 60% of bacteria growth, at 250 μg/mL inhibits 45% of bacteria growth, at 500μg/mL inhibits 65% of bacteria growth and at 1.000μg/mL inhibits 50% of bacteria growth. The streaking agar test result shows bacteria growth on every concentration. Conclusion: Red ginger (Zingiber officinale var. rubrum) ethanol extract in the concentration range of 62,5-1.000 μg/mL have no MIC and MBC value against Staphylococcus epidermidis.
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Zhang, Shiming, Xuefang Kou, Hui Zhao, Kit-Kay Mak, Madhu Katyayani Balijepalli, and Mallikarjuna Rao Pichika. "Zingiber officinale var. rubrum: Red Ginger’s Medicinal Uses." Molecules 27, no. 3 (January 25, 2022): 775. http://dx.doi.org/10.3390/molecules27030775.

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Zingiber officinale var. rubrum (red ginger) is widely used in traditional medicine in Asia. Unlike other gingers, it is not used as a spice in cuisines. To date, a total of 169 chemical constituents have been reported from red ginger. The constituents include vanilloids, monoterpenes, sesquiterpenes, diterpenes, flavonoids, amino acids, etc. Red ginger has many therapeutic roles in various diseases, including inflammatory diseases, vomiting, rubella, atherosclerosis, tuberculosis, growth disorders, and cancer. Scientific evidence suggests that red ginger exhibits immunomodulatory, antihypertensive, antihyperlipidemic, antihyperuricemic, antimicrobial, and cytotoxic activities. These biological activities are the underlying causes of red ginger’s therapeutic benefits. In addition, there have been few reports on adverse side effects of red ginger. This review aims to provide insights in terms the bioactive constituents and their biosynthesis, biological activities, molecular mechanisms, pharmacokinetics, and qualitative and quantitative analysis of red ginger.
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Supu, Rini Daud, Ajeng Diantini, and Jutti Levita. "RED GINGER (Zingiber officinale var. rubrum): ITS CHEMICAL CONSTITUENTS, PHARMACOLOGICAL ACTIVITIES AND SAFETY." FITOFARMAKA: Jurnal Ilmiah Farmasi 8, no. 1 (May 30, 2019): 23–29. http://dx.doi.org/10.33751/jf.v8i1.1168.

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Ginger (Zingiber officinale) which belongs to the Zingiberaceae family, was first cultivated in Asia (Indonesia and Malaysia). This plant is one of the most commonly used herbal supplements taken by many patients to treat various conditions. Z.officinale has three varieties based on its size, colors of rhizome and chemical constituents i.e. .Z. officinale var. officinale (big white ginger or giant ginger, badak or gajah), Z. officinale var. amarum (small white ginger, emprit), and Z. officinale var. rubrum (small red ginger, merah or beureum). These three varieties may partly be deferred from their essential oil contents and are used for different purposes. The essential oils contained in Z. officinale var. rubrum are higher than the other types of ginger, which makes stronger in its pungency smell and taste. There are many studies that confirm beneficial effects of red ginger against the symptoms of diseases, i.e. anti-inflammation, antioxidant, antiemetic, antibacterial and antidiabetics. Z.officinale var. rubrum is considered to be a safe herbal medicine with only few and insignificant adverse/side effects. Although the medicinal properties of red ginger have been known, further trials in humans are required to determine the efficacy of red ginger (or one or more of its constituents) and to establish what, if any, adverse effects are observed.
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19

Chen, Chung-Yi, Yu-Ting Yeh, and Woei-Ling Yang. "New Phenylalkanoids from Zingiber Officinale." Natural Product Communications 6, no. 6 (June 2011): 1934578X1100600. http://dx.doi.org/10.1177/1934578x1100600624.

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Two new phenylalkanoids, 3-hydroxy-1-(4′-hydroxy-3′-methoxy-phenyl)-hexan-5-one (1) and 3-hydroxy-1-(3′, 5′-dimethoxy-4′-hydroxy-phenyl)-hexan-5-one (2) were isolated from the rhizomes of Chinese ginger ( Zingiber officinale Roscoe (Zingiberaceae)). The structures of two new phenylalkanoids were elucidated by chemical and physical evidence.
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Owhorji, Bright, Chibuike Obiandu, Edith Reuben, and Buduka J. Otto. "Comparative Assessment of the Effects of Consumption of Ginger and Marijuana on Learning and Memory in Swiss Mice." Scholars International Journal of Anatomy and Physiology 5, no. 8 (December 30, 2022): 137–41. http://dx.doi.org/10.36348/sijap.2022.v05i08.004.

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A plethora of medicinal plants have been shown to improve memory, cognition, and intelligence. Zingiber officinale (Ginger) and Cannabis sativa (Marijuana) have been shown to affect memory, cognition, and intelligence too. This study aimed at comparing the effects of Zingiber officinale and Cannabis sativa on learning and memory was carried out in Swiss mice. The mice were randomly divided into 3 groups of 15 animals each. Group 1 (control) were fed mice feed. Group 2 (ginger group) were fed with a ginger-laced diet containing ginger and mice feed at a percentage ratio of 5:95. Group 3 (marijuana group) were fed with a marijuana-laced diet containing marijuana and mice feed at the percentage ratio of 5:95. All mice were fed for 14 days and given water to drink daily. Daily food and water intake were recorded. The mice were evaluated for learning and spatial memory using novel object recognition tests and data obtained were subjected to ANOVA and T test respectively. The result showed that the Zingiber officinale group showed significantly better memory as seen by an increase in the recognition index when compared to the other groups. This shows that Zingiber officinale shows positive effects on cognition than Cannabis sativa at the same dose.
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Sanavi, Suzan, and Reza Afshar. "Subacute thyroiditis following ginger (Zingiber officinale) consumption." International Journal of Ayurveda Research 1, no. 1 (2010): 47. http://dx.doi.org/10.4103/0974-7788.59944.

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22

Karkare, Manjusha. "Subacute thyroiditis following ginger (Zingiber officinale) consumption." International Journal of Ayurveda Research 1, no. 2 (2010): 134. http://dx.doi.org/10.4103/0974-7788.64403.

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23

Hayden, A. L., L. A. Brigham, and G. A. Giacomelli. "AEROPONIC CULTIVATION OF GINGER (ZINGIBER OFFICINALE) RHIZOMES." Acta Horticulturae, no. 659 (November 2004): 397–402. http://dx.doi.org/10.17660/actahortic.2004.659.52.

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Dev, H. "Genetic Variability in Ginger (Zingiber officinale Rosc.)." International Journal of Bio-resource and Stress Management 13, no. 7 (July 31, 2022): 709–17. http://dx.doi.org/10.23910/1.2022.2941a.

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The present investigations were carried out at the Experimental Farm of the Department of Vegetable Science, Dr. YS Parmar University of Horticulture and Forestry, Nauni, Solan (HP) during kharif season (April–November), 2011. The objective of the study was to assess the genetic variability of 40 diverse genotypes of ginger collected from different parts of the country including one recommended variety Himgiri as check. These genotypes had shown considerable variability for all the parameters studied. The observations were recorded on emergence, number of tillers and leaves plant-1, leaf length and breadth, plant girth and height, length, girth, core diameter and weight of mother, primary and secondary rhizomes, number of primary and secondary rhizomes plant-1, yield plant-1 plot-1ha-1, incidence of rhizome rot, dry matter and oleoresin content. The genotypic coefficients of variability (GCV) were moderate for number of secondary rhizomes plant-1, weight of primary and secondary rhizomes and yield plant-1 plot-1 ha-1, whereas, the phenotypic coefficients of variability (PCV) were moderate for emergence, number of tillers and leaves plant-1, number of secondary rhizomes plant-1, weight of mother, primary and secondary rhizomes, yield plant-1 plot-1 ha-1, oleoresin content and incidence of rhizome rot. High heritability coupled with high and moderate genetic gain was observed for yield plot-1 ha-1 and weight of mother, primary and secondary rhizomes indicating the importance of these characters for selection. It indicated that these traits were amenable to selection. The overall assessment showed that there was wide variability among ginger genotypes which has important implication for breeding ginger for yield and quality attributes.
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Dev, H., and Vipin sharma. "Genetic Divergence in Ginger (Zingiber officinale Rosc)." International Journal of Current Microbiology and Applied Sciences 9, no. 8 (August 2020): 3072–76. http://dx.doi.org/10.20546/ijcmas.2020.908.347.

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van Breemen, Richard B., Yi Tao, and Wenkui Li. "Cyclooxygenase-2 inhibitors in ginger (Zingiber officinale)." Fitoterapia 82, no. 1 (January 2011): 38–43. http://dx.doi.org/10.1016/j.fitote.2010.09.004.

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Sultana, S., N. Y. Mili, R. Afroz, and S. Parveen. "Preventive Role of Zingiber Officinale against Hyperglycemia in Alloxan Induced Diabetic Rats." Journal of Medical Science & Research 30, Number 1 (January 1, 2019): 26–29. http://dx.doi.org/10.47648/jmsr.2019.v3001.05.

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The experimental animal study was undertaken to investigate the preventive role ginger juice against hyperglycemia in alloxan induced diabetic rats.Male wistar rats,(130-150)gm wt fed on standard diet and water ad libitum, were divided into 3 groups(n=6) in each group: Group-L non-diabetic control group, Group-II, diabetic control & Group-III, normal rats pretreated with ginger before they were made diabetics. Diabetes was induced by inj. alloxan 150mg/kg body wt.,tp (Group-IL on 2nd day & Group-Ill, on the 9th day).Rats having blood glucose level of more than 7mmol/L on day 5(72 hours after alloxan inj) were considered diabetic & selected for experiment. Rats of Group-Ill received Zingiber officinale (ginger juice) (4m1/kg.body,wt orally) for 7 days (day 2-day8) through Pyles tube before alloxan induction & 3days after the induction. On day 12, animals were sacrificed under light ether anaesthesia, blood was collected by cardiac puncture for blood glucose estimation. Pretreatment with Zingiber officinale (ginger) juice significantly (p<0.01) reduced alloxan induced hyperglycemia.Zingiber officinale (ginger) is one of the most widely used spices and is reputed to have medicinal properties against diabetes mellitus. This study suggests that pretreatment with Zingiber officinale(ginger) prevents the development of hyperglycemia in alloxan induced diabetic rats.
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Loizzo, Monica Rosa, Patrizia Formoso, Mariarosaria Leporini, Vincenzo Sicari, Tiziana Falco, and Rosa Tundis. "Influence of Organic and Conventional Agricultural Practices on Chemical Profile, In Vitro Antioxidant and Anti-Obesity Properties of Zingiber officinale Roscoe." Medical Sciences Forum 2, no. 1 (November 30, 2020): 3. http://dx.doi.org/10.3390/cahd2020-08559.

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Ahmad, Albara, Safaa Jafar Mohammed, Ikram Mohamed Eltayeb, Yousif Mohammed Elmosaad, and Hisham Ali Waggiallah. "Comparative Study of the Anticoagulant Activity of Zingiber Officinale and Curcuma longa Rhizomes Extracts in Blood Samples of Normal Individuals." Pakistan Journal of Medical and Health Sciences 16, no. 5 (May 26, 2022): 348–51. http://dx.doi.org/10.53350/pjmhs22165348.

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Objective: The current study compares the anticoagulant activity of curcumin and ginger rhizome extracts in vitro. Background: Curcuma longa and Zingiber officinale (Ginger) (turmeric, curcuma, or curcumin) Rhizomes are widely used as a spice and in herbal medicine around the world. Methods: To obtain the entire crude extract, Zingiber officinale and Curcuma longa rhizomes were pulverized and extracted in 70% ethanol. The phytochemical contents of the extracts were determined. Their anticoagulant impact was tested in vitro on blood samples from healthy Sudanese people by assessing prothrombin time (PT) and activated partial thromboplastin time (APTT). Results: The ginger extract inhibited coagulation and significantly prolonged prothrombin time (PT) in a dose-dependent manner (25,50, 75 μl) with P. value 0.001, whereas APTT showed insignificant prolongation (P. value 0.139). PT and APTT of curcumin showed insignificant prolongation among (25, 50, 75μl) with P. value 0.55 and 0.146, respectively. Conclusion: The in vitro anticoagulant effect demonstrated that ginger and curcumin extracts had equal anticoagulant activity, but curcumin has a higher anticoagulant impact with considerable PT prolongation. Keywords: Zingiber officinale, Curcuma longa, Coagulation, PT, APTT.
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Robiansyah, Robiansyah, Debby Saputera, and Rahmad Arifin. "TOXICITY TEST OF SMALL WHITE GINGER EXTRACT ON BHK-21 FIBROBLAST CELLS IN VITRO." Dentino : Jurnal Kedokteran Gigi 5, no. 1 (March 12, 2020): 6. http://dx.doi.org/10.20527/dentino.v5i1.8113.

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Background: Denture stomatitis is inflammation of the oral mucosa which supporting the denture that caused by Candida albicans. Candida albicans contamination can be prevented by immersing dentures into denture cleanser solution. One of the alternative ingredients that can be used as denture cleanser is small white ginger rhizome (Zingiber officinale var. Amarum). Objective: This study aimed to analyze whether small white ginger extract (Zingiber officinale var. Amarum) was toxic to BHK-21 fibroblast cells using the MTT assay method. Method: This study was conducted in 7 groups. Five groups consisted of extracts of 30%, 40%, 50%, 60%, 70% and 2 control groups comprised of media control and cell control. Absorbance was read using ELISA reader and cell viability was calculated. Results: The percentage of living cells of all groups of small white ginger extract treatment was 100%. The parametric analysis of One Way Annova showed p = 0.498 (p> 0.05) Conclusion: Small white ginger extract (Zingiber officinale var. Amarum) is not toxic to BHK-21 fibroblast cells using the MTT Assay method because cell viability of all concentration groups is ≥ 60%.
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Kartini, Sri, and Uswatun Hasanah. "UJI LISIS TELUR Ascaris lumbricoides SETELAH PEMBERIAN EKSTRAK ETANOL 70% JAHE MERAH (Zingiber officinale var rubrum)." Klinikal Sains : Jurnal Analis Kesehatan 10, no. 2 (December 22, 2022): 147–55. http://dx.doi.org/10.36341/klinikal_sains.v10i2.2738.

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Worm infection is an environmental-based disease, can be transmitted through the soil or known as soil-transmitted helminth (STH). Infections caused by this parasite can be eradicated by administering synthetic drugs and herbal medicines. One of the plants that can be used as herbal medicine is red ginger (Zingiber officinale var rubrum). Red ginger (Zingiber officinale var rubrum) has one of the benefits, namely to treat intestinal worms. This study aimed to determine the lysis of Ascaris lumbricoides eggs after administration of 70% Ethanol Extract of Red Ginger (Zingiber officinale var rubrum). The method used in this research is a laboratory experiment. The results showed that at a concentration of 5% within 45 minutes there was no color change and there was no damage to the eggs of Ascarias lumbricoides, while at concentrations of 10% and 15% within 45 minutes it could cause changes in the color of the eggs and could lyse the eggs of Ascarias lumbricoides. Red ginger contains tannins, flavonoids, saponins and triterpenoids that are able to lyse eggs of Ascaris lumbricoides.
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Mao, Qian-Qian, Xiao-Yu Xu, Shi-Yu Cao, Ren-You Gan, Harold Corke, Trust Beta, and Hua-Bin Li. "Bioactive Compounds and Bioactivities of Ginger (Zingiber officinale Roscoe)." Foods 8, no. 6 (May 30, 2019): 185. http://dx.doi.org/10.3390/foods8060185.

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Ginger (Zingiber officinale Roscoe) is a common and widely used spice. It is rich in various chemical constituents, including phenolic compounds, terpenes, polysaccharides, lipids, organic acids, and raw fibers. The health benefits of ginger are mainly attributed to its phenolic compounds, such as gingerols and shogaols. Accumulated investigations have demonstrated that ginger possesses multiple biological activities, including antioxidant, anti-inflammatory, antimicrobial, anticancer, neuroprotective, cardiovascular protective, respiratory protective, antiobesity, antidiabetic, antinausea, and antiemetic activities. In this review, we summarize current knowledge about the bioactive compounds and bioactivities of ginger, and the mechanisms of action are also discussed. We hope that this updated review paper will attract more attention to ginger and its further applications, including its potential to be developed into functional foods or nutraceuticals for the prevention and management of chronic diseases.
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Sumon, M. Naimur Rahman, Tanjina Akhtar Banu, Sanjida Rahman Mollika, Barna Goswami, Mousona Islam, Shahina Akter, Ripa Akter Sharmin, and M. Salim Khan. "In vitro Regeneration of Ginger (Zingiber officinale Roscoe)." Plant Tissue Culture and Biotechnology 29, no. 2 (December 2, 2019): 151–59. http://dx.doi.org/10.3329/ptcb.v29i2.44504.

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An efficient and reproducible in vitro regeneration protocol was established for two varieties of ginger (Z. officinale Roscoe) namely, BARI Ada-1 and Chinese ginger accession number SG876). In case of BARI Ada-1 best result was obtained on MS supplemented with 2.0 mg/l BAP, 0.5 mg/l Kn and 0.5 mg/l NAA. In this combination, 95% rhizome bud explants responded within 6 - 8 days and mean number of shoots per explant was 8.79 ± 0.42. On the other hand, Chinese ginger showed best (90%) shoot regeneration response from the same explants on the same medium and hormonal combinations but in exchange of 0.25 mg/l NAA. In this hormonal composition shoot initiation started within 7 - 8 days of culture and mean number of shoots/explant was 6.83 ± 0.71 after 24 - 27 days of culture. Maximum root induction (90 and 80%) was found on MS supplemented with 0.5 mg/l IBA and 0.5 mg/l NAA in case of BARI Ada-1 and Chinese ginger, respectively. The in vitro regenerated plantlets were successfully transplanted into the soil after acclimatization.
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Gavrilova, Anna, Genadi Gavrilov, and Dora Trifonova. "Contribution to the microscopic identification of Zingiber officinale." Pharmacia 69, no. 1 (January 19, 2022): 93–97. http://dx.doi.org/10.3897/pharmacia.69.e78304.

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Zingiber officinale Roscoe has a very long history of use throughout the world, both as a spice and as a medicinal plant. During the last two years in the midst of a global pandemic of SARS-CoV-2 the use of various herbal products with ginger rhizome as active ingredient increased because of its numerous health beneficial properties. A detailed characteristic of the crude powdered drug is presented by microscopic photographs for the first time. Although the structure of ginger rhizome is relatively simple and well-studied, the presented results in combination with the detailed analysis of the literature provide additional insight to the pharmacopoeial guidelines for the identification of ginger powder.
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Murwati, Murwati. "PHYSICAL TEST AND HEDONIC TEST GINGER COOKIES (Zingiber officinale)." Jurnal Jamu Kusuma 1, no. 2 (May 27, 2022): 76–83. http://dx.doi.org/10.37341/jurnaljamukusuma.v1i2.20.

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Ginger (Zingiber officinale) is one type of medicinal plants in Indonesia that are often used as herbal medicine. The active substances contained in ginger are gingerol, shogaol, triterpenoids, flavonoids and saponins. Cookies are practical food because they can be eaten at any time and have a relatively long shelf life. Cookies can be seen as a good medium as one type of food that can meet the special needs of humans. Various types of cookies have been developed to produce cookies that are not only tasty but also healthy. Therefore researchers are interested in making ginger into cookies that are healthy and beneficial to the body. The purpose of this study is to find out the results of physical tests and tests hedonic cookies ginger (Zingiber officinale). The type of research conducted is observational with descriptive research design. The results of the study for organoleptic test obtained cookies brownish color, smell typical ginger, sweet taste and typical ginger, crispy texture. Physical test results are produced ie for pH test obtained on average 7, water content test results get an average 4.26%, ash content test gets an average results of 11.25%. Hedonic cookies test results for flat texture 2.28, color 2.6, taste 2.44 and aroma 2.52. Based on physical tests that have been done on ginger cookies the results obtained do not meet the requirements as determined.
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Suharto, Idola Perdana Sulistyoning, and Endang Mei Yunalia. "Preeliminary Study Efektivitas Bengkuang (Pachyrrhizus erosus) dan Jahe (Zingiber officinale roscoe) terhadap Kadar Kolesterol Total Pasien Diabetes Melitus." Jurnal Biotek Medisiana Indonesia 9, no. 2 (February 5, 2021): 106–12. http://dx.doi.org/10.22435/jbmi.v9i2.4414.

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Abstract Dyslipidemia is condition of a lipid metabolism disorder that characterized by high levels of total cholesterol, triglycerides, and Low-Density Lipoprotein (LDL), and low levels of High-Density Lipoprotein (HDL) cholesterol. Pharmacological therapy in dyslipidemia has several side effects. The purpose of this study was to determine the effectiveness of yam bean (Pachyrrhizus erosus) and ginger (Zingiber officinale roscoe) on total cholesterol levels of diabetics with the risk of dyslipidemia. This research is a comparative analytic study using the one-group pretest-posttest design approach. Samples were divided into two groups, namely the yam bean juice treatment group and ginger water treatment group. Yam bean juice and ginger water are given 2 times a day for 7 days. Data were analyzed using the Wilcoxon signed ranked test and paired T-test. The results of this study are that there is no difference in total cholesterol before and after administration of yam bean juice and there is a difference in total cholesterol before and after administration of ginger water. Ginger water (Zingiber officinale roscoe) is more effective than yam bean juice (Pachyrrhizus erosus) in decreasing the total cholesterol level of diabetics with the risk of dyslipidemia. Keywords: diabetes mellitus, ginger (Zingiber officinale roscoe), total cholesterol, yam bean (Pachyrrhizus erosus) Abstrak Dislipidemia merupakan kondisi metabolisme lipid yang tidak normal, ditandai dengan tingginya kadar kolesterol total, trigliserida, dan Low Density Lipoprotein (LDL), akan tetapi kadar kolesterol High Density Lipoprotein (HDL) rendah. Terapi farmakologi pada dislipidemia memiliki beberapa efek samping. Penelitian ini bertujuan untuk mengetahui efektivitas bengkuang (Pachyrrhizus erosus) dan jahe (Zingiber officinale roscoe) terhadap kadar kolesterol total penderita diabetes melitus (DM) dengan risiko dislipidemia. Penelitian ini merupakan penelitian analitik komparasi dengan menggunakan pendekatan the one group pretest–posttest design. Sample pada penelitian ini dikelompokkan menjadi 2 yaitu kelompok perlakuan jus bengkuang dan kelompok perlakuan air rebusan jahe. Jus bengkuang dan air rebusan jahe diberikan 2 kali sehari selama 7 hari. Data dianalisis menggunakan wilcoxon signed ranked test dan paired T-test. Hasil dari penelitian ini adalah tidak ada perbedaan kolesterol total sebelum dan sesudah pemberian jus bengkuang dan terdapat perbedaan kolesterol total sebelum dan sesudah pemberian air rebusan jahe. Pemberian air rebusan jahe (Zingiber officinale roscoe) lebih efektif dibandingkan jus bengkuang (Pachyrrhizus erosus) dalam menurunkan kadar kolesterol total penderita DM dengan risiko dislipidemia. Kata kunci: bengkuang (Pachyrrhizus erosus), diabetes melitus, jahe (Zingiber officinale roscoe), kolesterol total
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Nishidono, Yuto, Azis Saifudin, Mikio Nishizawa, Takashi Fujita, Masatoshi Nakamoto, and Ken Tanaka. "Identification of the Chemical Constituents in Ginger (Zingiber officinale) Responsible for Thermogenesis." Natural Product Communications 13, no. 7 (July 2018): 1934578X1801300. http://dx.doi.org/10.1177/1934578x1801300722.

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To compare the thermogenic properties of crude drugs derived from ginger, the activities to peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) of methanol extracts of “Shokyo” (dried rhizome of Z. officinale var. rubens), “Kankyo” (steamed and dried rhizome of Z. officinale var. rubens), “Red ginger” (Indonesian dried rhizome of Z. officinale var. rubrum) and “White ginger” (Indonesian dried rhizome of Z. officinale var. amarum), were examined. The extracts of the four specimens were analyzed by liquid chromatography mass spectrometry (LC-MS). The results showed that “Shokyo” and “White ginger” strongly stimulated PGC-1α and that the amount of [10]-shogaol (6) in these was higher than in “Kankyo” and “Red ginger”. Gingerol-related compounds were isolated or prepared in order to identify the compounds responsible for stimulating PGC-1α. As a result, [10]-gingerol (3), [10]-shogaol (6), [10]-gingerdiols (11, 12) and [10]-gingerdiols 3,5-diacetate (17, 18) were identified as the active constituents, while the main constituents, [6]-gingerol (1) and [6]-shogaol (4), did not show any significant PGC-1α activity. These results suggest that gingerol-related compounds with long alkyl side chains contribute to the thermogenic properties of ginger.
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Lu, Fengying, Hua Cai, Saimei Li, Wei Xie, and Rongjin Sun. "The Chemical Signatures of Water Extract of Zingiber officinale Rosc." Molecules 27, no. 22 (November 13, 2022): 7818. http://dx.doi.org/10.3390/molecules27227818.

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Background: Ginger (Z. officinale Rosc.) is a common herb and is widely used as a diet-based or home therapy in traditional medicine worldwide. However, fresh ginger turns into dried ginger after kiln drying and shows a different treatment effect in clinical practice. Objective: To characterize the changes of major bioactive constituents in dried ginger after the processing of fresh ginger. Methods: A novel, ultra-high-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry (UHPLC–QTOF/MS) method was established to characterize the changes in the bioactive constituents of dried ginger. The novel strategy was split into two steps: firstly, the MS selected the most intense precursor ions of tandem MS; then, target MS/MS acquisition with different collision energies (10, 20, and 40 eV) was used to characterize the compound’s accurate MS/MS spectra and compare the MS/MS spectrum with the building MS reference library and reference standards. Result: Fifty-three compounds, including diarylheptanoids, gingerols, gingerodiols, gingerdiones, and shogaol-related compounds, were identified based on summarized fragmentation patterns. Fifteen out of fifty-three compounds were diarylheptanoids, which was different from fresh ginger. Conclusion: These identified compounds could be used to characterize the quality of dried ginger, pharmacologic studies should focus on diarylheptanoids explaining the different treatment effects between fresh ginger and dried ginger.
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Mancini, S., G. Preziuso, F. Fratini, B. Torracca, R. Nuvoloni, A. Dal Bosco, and G. Paci. "Qualitative improvement of rabbit burgers using Zingiber officinale Roscoe powder." World Rabbit Science 25, no. 4 (December 28, 2017): 367. http://dx.doi.org/10.4995/wrs.2017.7656.

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The object of this study was to evaluate the effect of Zingiber officinale powder on physical-chemical traits, microbiological growth and sensory properties of rabbit burger. Raw burgers (only meat and meat added with 1 and 2% w/w ginger powder) were stored at 4°C for 1, 4 and 7 d and then cooked. Ginger modified the colour of both raw and cooked burgers, leading to more yellow hue and reducing lightness. Aspect of burgers were affected by ginger powder addition, leading to a noticeable difference between the samples. During storage time, the highest modifications were recorded for control samples, followed by burgers with added ginger. Sensory evaluation highlighted that ginger enhanced the juiciness of the burgers; moreover, burgers with ginger powder presented a significant delay in microbial growth. Ginger powder might be considered as a potential ingredient in rabbit meat products to increase their quality and extend their shelf-life.
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Agnaou, Nora, Zahira Lezar, Ahmed Belmouden, and Abdellah Houari. "Overview of health benefits of Zingiber Officinale extracts : An Update." (IJRE) International Journal of Research and Ethics (ISSN 2665-7481) 4, no. 1 (December 24, 2021): 44–56. http://dx.doi.org/10.51766/ijre.v4i1.179.

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Background: Ginger (Zingiber officinale Roscoe, family: Zingiberaceae) the powdered rhizomes of perennial herb, widely used as the most common spice in foods. Ginger root has been used as an aromatic and pungent additive over years. Recently ginger has gained a rapid emergence and considerable attention as an herbal medicine and potential source of bioactive constituents. Several studies have reported the therapeutic usefulness of ginger extracts as anti-oxidants, anti-inflammatory, anti-tumor, anti-ulcerogenic, anti-Alzheimer disease, and neuroprotective activities in the central nervous system. Objective: The aim of this review to provide a brief overview of the multiple health benefits and therapeutical properties of Ginger recently highlighted. Methods: We conducted an extensive search in the following databases: PUBMED, sciencedirect, EBSCO database in order to identify relevant studies according to edibility criteria. Results: The investigations revealed that ginger extract is the most powerful antioxidant and anti-inflammatory against cancer and others diseases with significant results . Conclusion: Finding open up the prospect of using ginger extract as a new alternative or additive that can improve treatment and therapeutic management. Keywords: Ginger, Zingiber officinale, extracts, bioactive constituents, therapeutic properties.
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Sultana, Selima, Shakil Akter, and Md Ismail Khan. "Anti-Hyperlipidemic Action of Zingiber officinale (Ginger) Juice in Alloxan Induced Diabetic Rats." Ibrahim Medical College Journal 6, no. 2 (April 23, 2013): 55–58. http://dx.doi.org/10.3329/imcj.v6i2.14730.

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Hyperlipidemia is an important modifiable risk factor contributing to atterosclerosis in diabetes mellitus. Zingiber officinale (ginger) widely consumed as spice is known for its hypoglycemic and hypochlosteremic actions. The present study was undertaken to investigate anti-hyperlipidemic action of ginger juice in alloxan-induced diabetic rats. Male Wister rats, 130-150 g wt, fed on standard diet and water ad libitum were divided into 4 groups (n=6 in each group): group I nondiabetic control, group II non-diabetic treated; group III diabetic control and group IV diabetic treated. Diabetes was induced by Inj. alloxan 150 mg Kg–1 b.w., i.p. (group III & IV) on Day 2. Rats having blood glucose level of >7 mmol/l on day 5 (72 hrs after alloxan Inj.) were considered diabetic and selected for experimentation. Both non-diabetic and diabetic treated groups (Gr II & IV) received Zingiber officinale (ginger) juice (4 ml Kg–1 b.w., p.o.) for 10 days (day 2-day 11) through Ryles tube. On Day 12, animals were sacrificed under light ether anaesthesia, blood was collected by cardiac puncture and serum separated for estimation of lipids. Zingiber officinale (ginger) juice significantly (p<0.01) decreased alloxan induced hyperglycemia (group IV), but had no effect on blood glucose level in normal rats (group II); significantly (p<0.001) reduced alloxan induced hyperlipidemia, but produced no significant lipid lowering effects in normal rats (group II).The results suggest a significant anti-hyperlipidemic action of Zingiber officinale (ginger) juice in alloxan induced diabetic rats. The findings may be clinically significant and exploited. DOI: http://dx.doi.org/10.3329/imcj.v6i2.14730 Ibrahim Med. Coll. J. 2012; 6(2): 55-58
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Yao, Jingjing, Zhenhua Du, Zibo Li, Shuhui Zhang, Yukun Lin, Haiyun Li, Lin Zhou, et al. "6-Gingerol as an arginase inhibitor prevents urethane-induced lung carcinogenesis by reprogramming tumor supporting M2 macrophages to M1 phenotype." Food & Function 9, no. 9 (2018): 4611–20. http://dx.doi.org/10.1039/c8fo01147h.

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Sarker, AK, M. Rashid, DC Roy, M. Musarrat, and UH Bithi. "Ginger (Zingiber officinale) powder from low temperature drying technique." Bangladesh Journal of Scientific and Industrial Research 56, no. 2 (June 23, 2021): 133–40. http://dx.doi.org/10.3329/bjsir.v56i2.54320.

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Ginger powder was prepared using different low temperature drying techniques and their nutritional, phytochemicals, functional and sensory quality were investigated. Moisture content was significantly (p<0.05) higher (7.16±0.04%) in shade dried powder and lowest in oven dried powder. Protein, fat and fiber contents varied with drying techniques ranging from 6.08±0.05 to 6.68±0.07%, 1.08±0.16 to 1.39±0.25% and 3.86±0.13 to 5.11±0.06% respectively. Highest alkaloid content was found in mechanical dried powder (4.44±0.04%), while highest flavonoid content was found in oven dried ginger powder (4.67±0.07%) and maximum saponin content was recorded in shade dried powder (2.67±0.10%). Highest ascorbic acid content (3.53±0.08 mg/100g) was found in shade dried powder and lowest was recorded in oven dried ginger powder (3.53±0.08 mg/100g). Sun drying technique exhibited better nutritional and sensory quality. The sensory score demonstrated that acceptance of all dried ginger powder was in the range of liked very much to liked moderately by the panelist. Low temperature drying techniques have positive significance on retaining phytochemicals and sensory quality of processed ginger. Bangladesh J. Sci. Ind. Res.56(2), 133-140, 2021
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Rahman, Md Abdur, Shyamal Kumar Shaha, Syed Didarul Haque, Refat Zahan, Tarifat Alam, Subir Kumar Mandal, and Md Shamsul Huda Mamun. "Antibacterial effect of Ginger (Zingiber officinale) against Staphylococcus aureus." Mediscope 7, no. 1 (May 17, 2020): 31–37. http://dx.doi.org/10.3329/mediscope.v7i1.47137.

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This experimental study was carried out to determine the antibacterial effect of Crude Ginger Extract (CGE) and Ethanolic Ginger Extract (EGE) against standard strain of Staphylococcus aureus in the Department of Pharmacology and Therapeutics with the collaboration of Department of Microbiology, Mymensingh Medical College, Mymensingh from July 2016 to June 2017. The growth of Staphylococcus aureus started to be inhibited from 70% CGE incorporated media and complete inhibition of growth occurred at 100% CGE. In case of Ethanolic Extract, sensitivity was seen against Staphylococcus aureus using disc diffusion method. Zones of inhibition were 8, 13 and 19 mm at 25, 50 and 100 μg/10 μl respectively. The minimum inhibitory concentration (MIC) of EGE was assessed by broth dilution technique. The MIC of EGE was 400 μg/ml against Staphylococcus aureus. From the study it is clearly observed that there is definite antibacterial effect of crude ginger extract (CGE) and ethanolic ginger extract against Staphylococcus aureus. Further studies are required to detect and isolate the active ingredients present in the Ginger extract responsible for antibacterial effect. Mediscope Vol. 7, No. 1: Jan 2020, Page 31-37
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Sanni, David M., and Toluwase H. Fatoki. "Computational Evaluation of Pharmacokinetics and Potential Protein Targets of Ginger (Zingiber officinale)." Journal of Microbiology and Biotechnology Research 7, no. 1 (March 29, 2017): 14. http://dx.doi.org/10.24896/jmbr.2017713.

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Ginger, the rhizome of the Zingiber officinale, a herbaceous tropical perennial plant which belong to the family Zingiberaceae. Ginger is a non-toxic highly promising natural compound having a wide spectrum of biological functions. In this study, selected bioactive components of ginger were computationally evaluated for therapeutic potential in relevance to human diseases using standard bioinformatics tools such as Pubchem, Swisstargetprediction and Swissadme. The result of this study showed that most of the targets obtained such as 5- hydroxytryptamine receptors, carbonic anhydrases and zinc finger proteins, have not been adequately researched in relation to the therapeutic potential of ginger. Ginger showed high potential in the prevention and management of cancer, neurodegenerative dementia and cardiovascular diseases in human, which could be administered alone or in combination with other drugs. Keyword: Ginger, Zingiber officinale, Target prediction, Computational pharmacokinetics, Human diseases, 5- Hydroxytryptamine receptors, Carbonic anhydrases, Zinc finger proteins.
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Mustafa, Iswaibah, and Nyuk Ling Chin. "Antioxidant Properties of Dried Ginger (Zingiber officinale Roscoe) var. Bentong." Foods 12, no. 1 (January 1, 2023): 178. http://dx.doi.org/10.3390/foods12010178.

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Ginger (Zingiber officinale Roscoe) is a popular culinary herb used in the Eastern culture. The essential cultivar of the Zingiber genus is rich in antioxidants and is crucial in the fight against oxidative stress-related diseases. The antioxidant properties of dried ginger were evaluated and compared for their efficacy from different drying processes (sun-, oven-, vacuum- and freeze-drying) and using three extraction solvents: hot water, aqueous ethanol (80%, v/v) and ethanol. The drying process demonstrated a positive effect on the antioxidant activities of ginger. A significant difference (p < 0.05) was observed in the extracting ability of each solvent. Sun-dried ginger extracted with ethanol performed better than the fresh ginger extract in the form of increased yield (3.04-fold), TFC values (12.25-fold), reducing power (FRAP) (15.35-fold), total antioxidant activity (TAA) (6.82-fold) and inhibition of ABTS•+ radical cation (3.51-fold) and DPPH• radical (95%). Meanwhile, freeze-dried aqueous ginger extracts demonstrated significantly higher TPC (1.66-fold), TFC (3.71-fold), FRAP (3.26-fold), TAA (2.97-fold), ABTS•+ scavenging activity (1.48-fold) and DPPH• radical inhibition (77%), compared to fresh ginger extracts. In addition, it was found that ethanol was significantly superior to aqueous ethanol in phenolic content recovery, despite the lower yield. Furthermore, ethanol ginger extracts exhibited higher antioxidant activity than aqueous ethanol extracts. On the other hand, hot water was the least potent solvent for extraction. In summary, there was an excellent correlation between TPC, TFC and antioxidant activity. Sun-drying is the most desirable method for preserving and enhancing ginger quality due to its cost effectiveness and bioactive compound efficacy.
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Kamil, Mohammad, F. Ahmad, and M. T. Abdallah. "Phytochemical, Pharmacognostic and Pharmacological Studies on Zingiber Officinale." Journal of Clinical and Laboratory Research 5, no. 1 (January 6, 2022): 01–07. http://dx.doi.org/10.31579/2768-0487/041.

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Rhizomes of Zingiber officinale Roscoe. belonging to the family Zingiberaceae is used for bronchitis, as a carminative, for treating cough, cataracts and as a stimulant. The rhizome is cooked with salt and water and used as an expectorant. Extract of the juice of rhizome is used as eye-drops. In Yemen, it is mixed with other plants used for constipation, as a purgative, against colds, catarrh and acidity of the stomach. Root ginger is widely used for culinary purposes and as a spice. The rhizomes (imported from India) are used with cinnamon and cloves and made into a tea for treating colds and as a general tonic. The drink is also used as an aphrodisiac (Gazanfar, 1994). Ginger is useful in piles, rheumatism, headache, lumbago, pains, bleeding, chest congestion, cholera, cold, diarrhea, dropsy, nausea, stomachache, gastrointestinal disorders, vomiting, and diarrhea. The fresh juice of ginger acts as a strong diuretic. The juice of the leaves is effective against helminthiasis and marasmus and related conditions of diarrhea and dysentery (Monograph of Unani Medicine,2003).
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Krishnapillai, N. "MEDICINAL VALUE OF GINGER (ZINGIBER OFFICINALE) IN JAFFNA." Acta Horticulturae, no. 680 (March 2005): 83–86. http://dx.doi.org/10.17660/actahortic.2005.680.10.

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B. Bag, Bijaya. "Ginger Processing in India (Zingiber officinale): A Review." International Journal of Current Microbiology and Applied Sciences 7, no. 04 (April 10, 2018): 1639–51. http://dx.doi.org/10.20546/ijcmas.2018.704.185.

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Taha, A. T. "MICROWAVE DRYING CHARACTERISTICS FOR GINGER ROOT (Zingiber officinale)." Misr Journal of Agricultural Engineering 32, no. 2 (April 1, 2015): 739–54. http://dx.doi.org/10.21608/mjae.2015.98632.

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