Academic literature on the topic 'Genome damage'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Genome damage.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Journal articles on the topic "Genome damage"
Proshkina, Ekaterina, Mikhail Shaposhnikov, and Alexey Moskalev. "Genome-Protecting Compounds as Potential Geroprotectors." International Journal of Molecular Sciences 21, no. 12 (June 24, 2020): 4484. http://dx.doi.org/10.3390/ijms21124484.
Full textHenkel, Ralf R., and Daniel R. Franken. "Sperm DNA Fragmentation: Origin and Impact on Human Reproduction." Journal of Reproductive and Stem Cell Biotechnology 2, no. 2 (December 2011): 88–108. http://dx.doi.org/10.1177/205891581100200204.
Full textLIU, Wei-Feng, Shan-Shan YU, Guan-Jun CHEN, and Yue-Zhong LI. "DNA Damage Checkpoint, Damage Repair, and Genome Stability." Acta Genetica Sinica 33, no. 5 (May 2006): 381–90. http://dx.doi.org/10.1016/s0379-4172(06)60064-4.
Full textAlhegaili, Alaa S., Yunhee Ji, Nicolas Sylvius, Matthew J. Blades, Mahsa Karbaschi, Helen G. Tempest, George D. D. Jones, and Marcus S. Cooke. "Genome-Wide Adductomics Analysis Reveals Heterogeneity in the Induction and Loss of Cyclobutane Thymine Dimers across Both the Nuclear and Mitochondrial Genomes." International Journal of Molecular Sciences 20, no. 20 (October 15, 2019): 5112. http://dx.doi.org/10.3390/ijms20205112.
Full textFerrand, Juliette, Beatrice Rondinelli, and Sophie E. Polo. "Histone Variants: Guardians of Genome Integrity." Cells 9, no. 11 (November 5, 2020): 2424. http://dx.doi.org/10.3390/cells9112424.
Full textThomas, Mark, Gaetan Burgio, David J. Adams, and Vivek Iyer. "Collateral damage and CRISPR genome editing." PLOS Genetics 15, no. 3 (March 14, 2019): e1007994. http://dx.doi.org/10.1371/journal.pgen.1007994.
Full textPetruseva, I. O., A. N. Evdokimov, and O. I. Lavrik. "Molecular Mechanism of Global Genome Nucleotide Excision Repair." Acta Naturae 6, no. 1 (March 15, 2014): 23–34. http://dx.doi.org/10.32607/20758251-2014-6-1-23-34.
Full textTrakhtenberg, I. M., Y. I. Gubsky, E. L. Levitsky, and I. F. Belenichev. "Biochemical mechanisms of free-radical damage to the nuclear genome by cadmium." Ukrainian Biochemical Journal 90, no. 3 (June 25, 2018): 5–16. http://dx.doi.org/10.15407/ubj90.03.005.
Full textCollura, Ada, Joel Blaisonneau, Giuseppe Baldacci, and Stefania Francesconi. "The Fission Yeast Crb2/Chk1 Pathway Coordinates the DNA Damage and Spindle Checkpoint in Response to Replication Stress Induced by Topoisomerase I Inhibitor." Molecular and Cellular Biology 25, no. 17 (September 1, 2005): 7889–99. http://dx.doi.org/10.1128/mcb.25.17.7889-7899.2005.
Full textHu, Jinchuan, Jason D. Lieb, Aziz Sancar, and Sheera Adar. "Cisplatin DNA damage and repair maps of the human genome at single-nucleotide resolution." Proceedings of the National Academy of Sciences 113, no. 41 (September 29, 2016): 11507–12. http://dx.doi.org/10.1073/pnas.1614430113.
Full textDissertations / Theses on the topic "Genome damage"
Banerjee, Ujjwal Kumar. "3-D Genome organization of DNA damage repair." Thesis, Strasbourg, 2017. http://www.theses.fr/2017STRAJ121.
Full textOur genome is constantly under attack by endogenous and exogenous factors which challenge its integrity and lead to different types of damages. Double strand breaks (DSBs) constitute the most deleterious type of damage since they maylead to loss of genetic information, translocations and cell death. All the repair processes happen in the context of a highly organized and compartmentalized chromatin. Chromatin can be divided into an open transcriptionally active compartment (euchromatin) and a compacted transcriptionally inactive compartment (heterochromatin). These different degrees of compaction play important roles in regulating the DNA damage response. The goal of my first project was to understand the influence of 3D genome organization on DNA repair. I used two complementary approaches to induce and map DSBs in the mouse genome. My results have shown that enrichment of the DNA damage repair factor γH2AX occurs at distinct loci in the mouse embryonic stem cell genome and that the damage persists in the heterochromatin compartment while the euchromatin compartment is protected from DNA damage. For my second project, I mapped the genomic footprint of 53BP1, a factor involved in DSBs repair, in asynchronous and G1 arrested U2OS cells to identify novel 53BP1 binding sites. My results have identified novel 53BP1 binding domains which cover broad regions of the genome and occur in mid to late replicating regions of the genome
Alrumaihi, Faris Abdulrahman I. "Assessment of UVR-induced DNA damage and repair in nuclear genome versus mitochondrial genome." Thesis, University of Leicester, 2016. http://hdl.handle.net/2381/37614.
Full textManning, Francis C. R. "The persistence of carcinogen damage in specific regions of the genome." Thesis, University of Nottingham, 1990. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.277377.
Full textAlpi, Arno. "DNA damage checkpoint pathways and the maintenance of genome stability in C. elegans." Diss., lmu, 2004. http://nbn-resolving.de/urn:nbn:de:bvb:19-24487.
Full textKasparek, Torben Rudolf. "Identification and characterisation of determinants of genome stability in response to a double-strand break." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:78e0a145-22c8-4abd-a746-e18c1939f5c9.
Full textDurant, Stephen Thomas. "The role of DNA mismatch repair in cellular responses to DNA damage and drug resistance." Thesis, University of Glasgow, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.312133.
Full textFrigola, Rissech Joan 1991. "Determinants of the local mutation rate variability along the genome." Doctoral thesis, Universitat Pompeu Fabra, 2020. http://hdl.handle.net/10803/669530.
Full textLa velocitat a la que les mutacions s’acumulen al llarg del genoma no és uniforme sinó que depèn de diversos factors. Alguns dels més coneguts són l’empaquetament de la cromatina, el moment de replicació o la transcripció. La majoria d’aquests factors creen variacions mutacionals que abarquen grans àrees del genoma, incloent varies megabases. En els últims anys, però, també s’ha identificat variabilitat en el ritme en que s’acumulen les mutacions a escala molt més petita, en regions de poques bases. Aquesta tesi es centra en l’estudi de dos d’aquestes variacions locals en el ritme en que les mutacions tenen lloc. Primer, hem descrit una reducció en el número de mutacions somàtiques en els exons causades per errors de la AND polimerasa, que hem atribuït a una major eficàcia del mecanisme encarregat aquest tipus d’errors en els exons. En segon lloc, hem estudiat com les lesions en el DNA causades per la llum ultraviolada es generen i són reparades als llocs d’unió dels factors de transcripció i hem determinat fins a quin punt cada un d’aquests processos permeten explicar l’inesperat número de mutacions en aquestes regions. La presència d’aquestes variacions locals la velocitat a la que les mutacions s’acumulen al llarg del genoma posen de manifest la dificultat de modelar correctament aquest procés, un procediment central en molts estudis evolutius i de genòmica del càncer.
Blance, Stephen J. "DNA repair and recombination in Streptomyces coelicolor." Thesis, University of Liverpool, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367139.
Full textFinneran, Bryan P. "Developing and Testing an ELISA Biosensor for Measuring UV-Induced Viral Genome and Protein Damage." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1593640837647181.
Full textBhattacharjee, Sonali. "The role of Fml1 and its partner proteins Mhf1 and Mhf2 in promoting genome stability." Thesis, University of Oxford, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.711640.
Full textBooks on the topic "Genome damage"
Aging of the genome: The dual role of the DNA in life and death. Oxford ; New York: Oxford University Press, 2007.
Find full textYosef, Shiloh, and SpringerLink (Online service), eds. The DNA Damage Response: Implications on Cancer Formation and Treatment. Dordrecht: Springer Netherlands, 2009.
Find full textGenes and the environment. London: Taylor & Francis, 1999.
Find full textAchary, V. Mohan Murali, Anca Macovei, Kaoru Okamoto Yoshiyama, and Ayako N. Sakamoto, eds. Maintenance of Genome Integrity: DNA Damage Sensing, Signaling, Repair and Replication in Plants. Frontiers Media SA, 2016. http://dx.doi.org/10.3389/978-2-88919-820-7.
Full textVijg, Jan. Aging of the Genome: The Dual Role of DNA in Life and Death. Oxford University Press, USA, 2007.
Find full textVijg, Jan. Aging of the Genome: The Dual Role of DNA in Life and Death. Oxford University Press, USA, 2007.
Find full textDodds, Chris, Chandra M. Kumar, and Frédérique Servin. Pathophysiological changes of ageing and their relevance to anaesthesia. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198735571.003.0002.
Full textClement, Jan, and Piet Maes. Hantaviral infections. Edited by Vivekanand Jha. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0188_update_001.
Full textCattran, Daniel C., and Heather N. Reich. Membranous glomerulonephritis. Edited by Neil Turner. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0064_update_001.
Full textCatherine, Rice-Evans, and Burdon R. H, eds. Free radical damage and its control. Amsterdam: Elsevier, 1994.
Find full textBook chapters on the topic "Genome damage"
Rasmussen, Lene Juel, and Keshav K. Singh. "Oxidative Damage and Repair in the Mitochondrial Genome." In Oxidative Damage to Nucleic Acids, 109–22. New York, NY: Springer New York, 2007. http://dx.doi.org/10.1007/978-0-387-72974-9_9.
Full textEvans, M. D., and M. S. Cooke. "Oxidative Damage to DNA in Non-Malignant Disease: Biomarker or Biohazard?" In Genome and Disease, 53–66. Basel: KARGER, 2006. http://dx.doi.org/10.1159/000092500.
Full textEppink, Berina, Jeroen Essers, and Roland Kanaar. "Interplay and Quality Control of DNA Damage Repair Mechanisms." In Genome Organization and Function in the Cell Nucleus, 395–415. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2011. http://dx.doi.org/10.1002/9783527639991.ch16.
Full textRichard, Derek J., and Kum Kum Khanna. "Single-Stranded DNA Binding Proteins Involved in Genome Maintenance." In The DNA Damage Response: Implications on Cancer Formation and Treatment, 349–66. Dordrecht: Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-90-481-2561-6_16.
Full textGolato, T., and D. M. Wilson III. "Chapter 30. DNA Damage and the Maintenance of Nuclear Genome Integrity in Aging and Associated Phenotypes." In DNA Damage, DNA Repair and Disease, 388–425. Cambridge: Royal Society of Chemistry, 2020. http://dx.doi.org/10.1039/9781839162541-00388.
Full textMao, Peng, and John J. Wyrick. "Genome-Wide Mapping of UV-Induced DNA Damage with CPD-Seq." In The Nucleus, 79–94. New York, NY: Springer US, 2020. http://dx.doi.org/10.1007/978-1-0716-0763-3_7.
Full textMitra, J., H. Wang, M. Kodavati, S. Mitra, and M. L. Hegde. "Chapter 13. Emerging Roles of Non-canonical RNA Binding Proteins in the Repair of Genome Damage Linked to Human Pathologies." In DNA Damage, DNA Repair and Disease, 301–22. Cambridge: Royal Society of Chemistry, 2020. http://dx.doi.org/10.1039/9781839160769-00301.
Full textSakai, Wataru, and Kaoru Sugasawa. "DNA Damage Recognition and Repair in Mammalian Global Genome Nucleotide Excision Repair." In DNA Replication, Recombination, and Repair, 155–74. Tokyo: Springer Japan, 2016. http://dx.doi.org/10.1007/978-4-431-55873-6_7.
Full textRechkunova, N. I., and O. I. Lavrik. "Nucleotide Excision Repair in Higher Eukaryotes: Mechanism of Primary Damage Recognition in Global Genome Repair." In Subcellular Biochemistry, 251–77. Dordrecht: Springer Netherlands, 2009. http://dx.doi.org/10.1007/978-90-481-3471-7_13.
Full textRavi, Dashnamoorthy, and Alexander James Roy Bishop. "Identification of Genes Required for Damage Survival Using a Cell-Based RNAi Screen Against the Drosophila Genome." In Methods in Molecular Biology, 9–26. Totowa, NJ: Humana Press, 2012. http://dx.doi.org/10.1007/978-1-61779-998-3_2.
Full textConference papers on the topic "Genome damage"
"Lesion recognition and cleavage of damage-containing G-quadruplexes by DNA glycosylases." In Bioinformatics of Genome Regulation and Structure/ Systems Biology. institute of cytology and genetics siberian branch of the russian academy of science, Novosibirsk State University, 2020. http://dx.doi.org/10.18699/bgrs/sb-2020-357.
Full text"DNA damage to nervous tissue due to lead intoxication combined with glucose loading." In Bioinformatics of Genome Regulation and Structure/ Systems Biology. institute of cytology and genetics siberian branch of the russian academy of science, Novosibirsk State University, 2020. http://dx.doi.org/10.18699/bgrs/sb-2020-338.
Full textGreen, Abby M., Sebastien Landry, James P. Evans, Sophia Shalhout, Ashok S. Bhagwat, and Matthew D. Weitzman. "Abstract 3016: APOBEC3 enzymes induce damage to the cellular genome during DNA replication." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-3016.
Full textGilbertson, Matthew, Radhika Patel, Karin C. Nitiss, and John L. Nitiss. "Abstract 3580: Topoisomerase II mediated DNA damage generates unique classes of genome rearrangements." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-3580.
Full textWeaver, Alice N., Tiffiny S. Cooper, Hoa Q. Trummell, James A. Bonner, Eben L. Rosenthal, and Eddy S. Yang. "Abstract A1-63: Characterizing the DNA damage repair defect in HPV-positive oropharyngeal squamous cell carcinoma." In Abstracts: AACR Special Conference: Translation of the Cancer Genome; February 7-9, 2015; San Francisco, CA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.transcagen-a1-63.
Full textAlhegaili, Alaa, George D. Jones, and Marcus S. Cooke. "Abstract LB-163: Genome-wide analysis of DNA damage and repair reveals differential sites and rates of repair, together with differential sensitivities to damage." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-lb-163.
Full textLu, Wei-ting, Lykourgos-Panagiotis Zalmas, Thomas Webber, Nnennaya Kanu, and Charles Swanton. "Abstract 2567: TRACERx: Intra-tumor subclonal driver mutation results in defective DNA damage response (DDR) and genome instability." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-2567.
Full textLu, Wei-ting, Lykourgos-Panagiotis Zalmas, Thomas Webber, Nnennaya Kanu, and Charles Swanton. "Abstract 2567: TRACERx: Intra-tumor subclonal driver mutation results in defective DNA damage response (DDR) and genome instability." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-2567.
Full textGout, J., L. Perkhofer, M. Morawe, F. Arnold, E. Roger, M. Müller, T. Seufferlein, Frappart PO, and A. Kleger. "PARP inhibitor resistance induces massive genome alterations responsible of the acquisition of multidrug resistance in DNA damage repair-deficient pancreatic cancer." In DGVS Digital: BEST OF DGVS. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1716148.
Full textDaly, G., C. M. Francis, V. M. Pastukh, D. Absher, R. J. Langley, and M. N. Gillespie. "Rapid Redistribution of Oxidative Base Damage in DNA Regulatory Sequences Accompanies Transcriptional Modulation by Hypoxia in the Human Endothelial Cell Genome." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4191.
Full textReports on the topic "Genome damage"
Dynan, William S. Links between persistent DNA damage, genome instability, and aging. Office of Scientific and Technical Information (OSTI), November 2016. http://dx.doi.org/10.2172/1332061.
Full textStewart, Robert D. Kinetic Modeling of Damage Repair, Genome Instability, and Neoplastic Transformation. Office of Scientific and Technical Information (OSTI), March 2007. http://dx.doi.org/10.2172/900981.
Full textDynan, William S. Final report- Links between persistent DNA damage, genome instability, and aging. Office of Scientific and Technical Information (OSTI), November 2016. http://dx.doi.org/10.2172/1333814.
Full textMordes, Daniel, Heather L. Ball, Mark Ehrhardt, Daniel Mordes, and David Cortez. Maintenance of Genome Stability and Breast Cancer: Molecular Analysis of DNA Damage-Activated Kinases. Fort Belvoir, VA: Defense Technical Information Center, March 2008. http://dx.doi.org/10.21236/ada494969.
Full textBall, Heather L., Mark Ehrhardt, Daniel Mordes, and David Cortez. Maintenance of Genome Stability and Breast Cancer: Molecular Analysis of DNA Damage-Activated Kinases. Fort Belvoir, VA: Defense Technical Information Center, March 2007. http://dx.doi.org/10.21236/ada470345.
Full textAbagyan, Ruben, and Jianghong An. Genome-Wide Identification and 3D Modeling of Proteins involved in DNA Damage Recognition and Repair (Final Report). Office of Scientific and Technical Information (OSTI), August 2005. http://dx.doi.org/10.2172/893896.
Full textRuben A. Abagyan, PhD. Genome-Wide Identification and 3D Modeling of Proteins involved in DNA Damage Recognition and Repair (Final Report). Office of Scientific and Technical Information (OSTI), April 2004. http://dx.doi.org/10.2172/823103.
Full textGreen, Brian M. DNA Damage and Genomic Instability Induced by Inappropriate DNA Re-Replication. Fort Belvoir, VA: Defense Technical Information Center, April 2005. http://dx.doi.org/10.21236/ada436928.
Full textGreen, Brian M., and Joachim J. Li. DNA Damage and Genomic Instability Induced by Inappropriate DNA Re-replication. Fort Belvoir, VA: Defense Technical Information Center, April 2007. http://dx.doi.org/10.21236/ada467931.
Full textGreen, Brian. DNA Damage and Genomic Instability Induced by Inappropriate DNA Re-replication. Fort Belvoir, VA: Defense Technical Information Center, April 2006. http://dx.doi.org/10.21236/ada482750.
Full text