Relevant bibliographies by topics / Genetics, Experimental

Academic literature on the topic 'Genetics, Experimental'

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Published: 4 June 2021
Last updated: 1 February 2022

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Journal articles on the topic "Genetics, Experimental"

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Teotónio, Henrique, Suzanne Estes, Patrick C. Phillips, and Charles F. Baer. "Experimental Evolution withCaenorhabditisNematodes." Genetics 206, no. 2 (June 2017): 691–716. http://dx.doi.org/10.1534/genetics.115.186288.

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Dominiczak, Anna F., James S. Clark, Baxter Jeffs, Niall H. Anderson, Cervantes D. Negrin, Wai K. Lee, and M. Julia Brosnan. "Genetics of experimental hypertension." Journal of Hypertension 16, Supplement (December 1998): 1859–69. http://dx.doi.org/10.1097/00004872-199816121-00003.

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Nilsson, Annika I., Elisabeth Kugelberg, Otto G. Berg, and Dan I. Andersson. "Experimental Adaptation ofSalmonella typhimuriumto Mice." Genetics 168, no. 3 (November 2004): 1119–30. http://dx.doi.org/10.1534/genetics.104.030304.

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McClosky, B., and S. D. Tanksley. "Optimizing Experimental Design in Genetics." Journal of Optimization Theory and Applications 157, no. 2 (September 18, 2012): 520–32. http://dx.doi.org/10.1007/s10957-012-0172-9.

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Silverman, Sanford J. "Experimental techniques in bacterial genetics." Analytical Biochemistry 192, no. 1 (January 1991): 254. http://dx.doi.org/10.1016/0003-2697(91)90219-j.

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Crow, James F., and Seymour Abrahamson. "Seventy Years Ago: Mutation Becomes Experimental." Genetics 147, no. 4 (December 1, 1997): 1491–96. http://dx.doi.org/10.1093/genetics/147.4.1491.

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Dykhuizen, Daniel E., and Antony M. Dean. "Evolution of Specialists in an Experimental Microcosm." Genetics 167, no. 4 (August 2004): 2015–26. http://dx.doi.org/10.1534/genetics.103.025205.

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Colegrave, N., and S. Collins. "Experimental evolution: experimental evolution and evolvability." Heredity 100, no. 5 (January 23, 2008): 464–70. http://dx.doi.org/10.1038/sj.hdy.6801095.

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Cesarini, David, Christopher T. Dawes, Magnus Johannesson, Paul Lichtenstein, and Björn Wallace. "Experimental Game Theory and Behavior Genetics." Annals of the New York Academy of Sciences 1167, no. 1 (June 2009): 66–75. http://dx.doi.org/10.1111/j.1749-6632.2009.04505.x.

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Johnston, Mark, and Oliver Hobert. "Extending Our Experimental Reach: Toolbox Reviews in GENETICS." Genetics 192, no. 1 (September 2012): 1. http://dx.doi.org/10.1534/genetics.112.143578.

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Dissertations / Theses on the topic "Genetics, Experimental"

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Dahlman, Ingrid. "Genetic dissection of experimental autoimmune neuroinflammatory diseases in rats /." Stockholm, 1999. http://diss.kib.ki.se/1999/91-628-3768-0/.

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Jagodić, Maja. "The complex genetics of experimental autoimmune neuroinflammation /." Stockholm, 2004. http://diss.kib.ki.se/2004/91-7140-157-1/.

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Lux, Melissa McNeil. "A laboratory course in experimental genetics for the biology major." Thesis, University of North Texas, 2001. https://digital.library.unt.edu/ark:/67531/metadc3007/.

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This manual has been designed for a class of twenty- four students concurrently enrolled in the lecture course. The laboratory aids in the learning process and fosters an interest in the science of genetics. This manual and the experiments contained within are both informative and fun. The manual correlates with and expands upon the genetics course. Each investigation, with the exception of the Drosophila melanogaster project, can be completed in a 3-4 hour timeframe. This manual provides a “hands on” experience of theories simply discussed in the lecture course. This manual is intended to be a one-source manual where each investigation is designed to include an adequate introduction. Special attention has been given for each investigation with both the student and instructor in mind.
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Reodica, Mayfebelle Biotechnology &amp Biomolecular Sciences Faculty of Science UNSW. "Transcriptional repression mechanisms of sporulation-specific genes in saccharomyces cerevisiae." Awarded by:University of New South Wales. School of Biotechnology and Biomolecular Sciences, 2006. http://handle.unsw.edu.au/1959.4/32731.

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For organisms undergoing a developmental process it is ideal that specific genes are induced and repressed at the correct time and to the correct level in a coordinated manner. The process of meiosis and spore formation (collectively known as sporulation) in Saccharomyces cerevisiae provides a convenient system to elucidate transcriptional mechanisms of gene repression and the contribution such repression mechanisms offer to cells capable of undergoing a developmental process. This thesis focuses on transcriptional repression of sporulation-specific genes during both vegetative/mitotic conditions and sporulation. The fitness contribution of transcriptional repressors that regulate sporulationspecific genes during vegetative growth were investigated considering the similarities between meiosis and mitosis such as DNA replication, chromosome segregation and cytokinesis. Well-characterised sporulation genes of different functions were expressed in vegetative cells and ectopic expression of these genes was found not to be lethal. It was ascertained through strain competition studies that ectopic expression of the genes IME1, SMK1, SPR3 and DIT1 during mitotic growth did not affect cellular fitness. The expression of NDT80 in vegetative cells, however, caused a marked reduction in fitness and cells were also further compromised in the absence of the Sum1p repressor that regulates NDT80 transcription. The role of NDT80 as a transcriptional activator of middle sporulation genes, rather than the over-expression of NDT80 as a protein, caused the reduction of cell viability. Transcriptional regulation of the middle sporulation-specific gene SPR3 by the meiosis-specific Set3p repressor complex was investigated using synchronous sporulation cultures of the W303a/?? strain commonly used for sporulation studies. In a mutant W303a/?? ??set3/??set3 strain, lacking a key component of the Set3p repression complex, the transcription of SPR3 was uncharacteristically expressed at higher levels and derepressed during late sporulation. This SPR3 expression was consistent for both SPR3 transcript and SPR3::lacZ reporter protein studies. This preliminary work will enable future studies, using SPR3 promoter deletions fused to a lacZ reporter, aimed at determining the region of the SPR3 promoter that the Set3p complex may interact with to transcriptionally repress the gene during sporulation.
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Johnson, Sarah J. "Sinusoidal cell responses to experimental liver injury." Thesis, University of Newcastle Upon Tyne, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.320389.

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Ono, Jasmine. "Genetics of adaptation in experimental populations of yeast." Thesis, University of British Columbia, 2017. http://hdl.handle.net/2429/64159.

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Evolution proceeds through genetic changes to individuals, which are either propagated or disappear over generations. Adaptation is one of the main mechanisms driving these changes in genetic composition. Speciation can also result from different, and incompatible, genetic changes occurring in different populations. This thesis furthers our knowledge of the genetics of adaptation and speciation using the budding yeast Saccharomyces cerevisiae. My work on the genetic basis of adaptation to high concentrations of copper, when contrasted with a similar experiment using the fungicide nystatin, showed that the environment has a strong influence on both the number of genes that are the targets of selection and the types of potentially beneficial mutations. These results have implications for the repeatability of genetic evolution. In a second study, I found that genetic interactions between individually isolated single-step beneficial mutations from the same selective environment often exhibited the type of epistasis that underlies speciation even though these mutations occurred within a single biosynthetic pathway. These results support the mutation-order model of speciation by adaptation, where the chance order of mutations in separated populations leads to divergence and the build-up of reproductive isolation due to genetic incompatibility. Negative genetic interactions became positive when the level of stress was increased, indicating that genetically-based reproductive isolation can also be environment-dependent. Finally, I found that diploid yeast were generally not able to adapt to a level of fungicide to which haploid yeast can adapt. Diploids have been found to adapt to a lower concentration of the same drug, indicating that the exact environment (type and concentration) and ploidy can have an impact on the likelihood of genetic rescue. Together, these results have implications for our understanding of the genetic basis of adaptation in different types of environments and different levels of the same environmental stressor.
Science, Faculty of
Zoology, Department of
Graduate
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Herath, Shanti Irene. "Characterisation of CD+ T cells in experimental cutaneous Leishmaniasis." Thesis, Imperial College London, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.269692.

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Sinha, S. "The role of oncogenes in experimental rat liver cancer." Thesis, Open University, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.234898.

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Gifford, Danna R. "Population genetics of rifampicin-resistant Pseudomonas aeruginosa." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:044b9258-4f10-4e77-9ff6-aa4035cec33b.

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Antibiotic resistance is generally associated with a cost in terms of reduced competitive fitness in the absence of antibiotics. Despite this 'cost of resistance', the cessation of antibiotic treatment does not result in significant reductions in the prevalence of resistance. The maintenance of resistance, in spite of the costs, has been attributed to the rarity of reversion mutations, relative to compensatory mutations at other loci in the genome. However, the large size of bacteria populations, and the potential for migration, suggest that reversion mutations should occasionally be introduced to resistant populations. In this thesis, I show that additional mechanisms can prevent fixation of reversion mutations even if they do occur. Using an experimental evolution approach, with rifampicin resistance in Pseudomonas aeruginosa as a model system, I measured the costs of resistance in several environments and followed the adaptive dynamics of resistant populations where a sensitive lineage had invaded by migration. The results suggest that several additional mechanisms contribute to the maintenance of antibiotic resistance. Most rifampicin resistance mutations are not unconditionally costly in all environments, suggesting that migration between environments could maintain a resistant reservoir population. In environments where resistance is initially costly, the fixation of a revertant is not guaranteed, even if introduced through migration. Revertant fixation was impeded or prevented by clonal interference from adaptation in the resistant strain. Revertants that did successfully replace the resistant strain were forced to adapt to do so. Contrary to assumptions in the existing literature, fitness in the resistant strains was not recovered by general compensatory mutations, but instead by adaptive mutations specific to the environment. The data challenge several assumptions about the maintenance of antibiotic resistance: that resistance mutations are always costly, that the rarity of back mutations prevents the reversion of resistance, and that resistant strains recover fitness by compensatory mutations.
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DIAS, VIVIANE L. "Aspectos da resistencia a infeccao experimental com Trypanosoma cruzi." reponame:Repositório Institucional do IPEN, 2010. http://repositorio.ipen.br:8080/xmlui/handle/123456789/9609.

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IPEN/D
Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP
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Books on the topic "Genetics, Experimental"

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Maloy, Stanley R. Experimental techniques in bacterial genetics. Boston: Jones and Bartlett, 1990.

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Maloy, Stanley R. Experimental techniques in bacterial genetics. Boston: Jones and Bartlett, 1989.

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Experimental leukemia: History, biology and genetics. Hauppauge, N.Y: Nova Science Publishers, 2009.

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Lawrence, M. J. Studies in experimental quantitative and population genetics. Birmingham: University of Birmingham, 1987.

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Double helix: A novel. Dallas: Word Pub., 1995.

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Run. New York: Razorbill, 2012.

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Brookes, Martin. Fly: An experimental life. London: Weidenfeld & Nicolson, 2001.

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Lords of the fly: Drosophila genetics and the experimental life. Chicago: University of Chicago Press, 1994.

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D'Arc, Bianca. A darker shade of dead. New York: Brava/Kensington Books, 2010.

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Fremdling: Roman. Hamburg: Hoffmann und Campe, 2012.

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Book chapters on the topic "Genetics, Experimental"

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Dyban, A. P. "Experimental Cytogenetics of Preimplantation Development." In Preimplantation Genetics, 15–23. Boston, MA: Springer US, 1991. http://dx.doi.org/10.1007/978-1-4684-1351-9_3.

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Neyrolles, Olivier, and Brigitte Gicquel. "Experimental Genetics ofMycobacterium tuberculosis." In Handbook of Tuberculosis, 379–91. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2017. http://dx.doi.org/10.1002/9783527611614.ch16.

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Hallauer, Arnel R., Marcelo J. Carena, and J. B. Miranda Filho. "Selection: Experimental Results." In Quantitative Genetics in Maize Breeding, 291–382. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-0766-0_7.

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Guénet, Jean-Louis, Fernando Benavides, Jean-Jacques Panthier, and Xavier Montagutelli. "Mutations and Experimental Mutagenesis." In Genetics of the Mouse, 221–65. Berlin, Heidelberg: Springer Berlin Heidelberg, 2014. http://dx.doi.org/10.1007/978-3-662-44287-6_7.

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Vogler, George P., and David W. Fulker. "Human Behavior Genetics." In Handbook of Multivariate Experimental Psychology, 475–503. Boston, MA: Springer US, 1988. http://dx.doi.org/10.1007/978-1-4613-0893-5_15.

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Benavides, Fernando, and Jean-Louis Guénet. "Rodent Genetics." In Experimental Design and Reproducibility in Preclinical Animal Studies, 11–52. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-66147-2_2.

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Worwood, M., M. T. Dorak, R. Raha-Chowdhury, and C. Darke. "Genetics of Haemochromatosis." In Advances in Experimental Medicine and Biology, 309–18. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2554-7_33.

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Encinas, J. A., and V. K. Kuchroo. "Genetics of Experimental Autoimmune Encephalomyelitis." In Genes and Genetics of Autoimmunity, 247–72. Basel: KARGER, 1999. http://dx.doi.org/10.1159/000060485.

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Noebels, J. L. "Experimental Neurogenetics of the Epilepsies." In Genetics of the Epilepsies, 184–90. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-95553-2_23.

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Hallauer, Arnel R., Marcelo J. Carena, and J. B. Miranda Filho. "Hereditary Variance: Experimental Estimates." In Quantitative Genetics in Maize Breeding, 169–221. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-0766-0_5.

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Conference papers on the topic "Genetics, Experimental"

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"Genetic structure of the ampelographic collection maintained in the Dagestan experimental station of VIR revealed by microsatellite analysis." In Current Challenges in Plant Genetics, Genomics, Bioinformatics, and Biotechnology. Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences Novosibirsk State University, 2019. http://dx.doi.org/10.18699/icg-plantgen2019-11.

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Kulik, M. J., D. S. Shenoda, and C. R. Forest. "A Low-Cost, Two-Axis, Precision Robot for Automated Fluorescence In-Situ Hybridization Assays." In ASME 2009 International Mechanical Engineering Congress and Exposition. ASMEDC, 2009. http://dx.doi.org/10.1115/imece2009-13272.

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Genetics research often relies on experiments that require repetitive, time-consuming handling of small volumes of liquid (1 mL) and biomass (10–20 μL) such as fluorescence in-situ hybridization (FISH), β-galactosidase staining, immunohisto chemistry, skeletal and tunel assays. Often manual, these experiments are time intensive and error-prone. We report on the design, fabrication, and testing of a low-cost, two-axis, precision robot for FISH assays on whole mice embryos. The robot can complete 20 successive embryo immersions in unique isothermal solutions in minutes for 6 samples. Repeatability of the orthogonal axes is 66 and 214 μm, near the measurement uncertainty limit and sufficient for operation. Accuracy is achieved by systematic error compensation. Low-cost and precision are obtained using design and manufacturing techniques and processes, resulting in a cost of 15% of comparable instruments (e.g., InsituStain, Intavis Bioanalytical Instruments). This design demonstrates a simple, automated platform to perform a typically manual experimental genetics technique.
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Mattison, Lars M., Taylor N. Suess, Michael P. Twedt, and Stephen P. Gent. "Comparison of Theoretical and Experimental Corn Drying Profiles Within a Cross-Flow Column Dryer." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-64557.

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This study compared the drying characteristics of corn within a continuous flow dryer under a variety of operating conditions. The tests were completed on a pilot scale cross flow corn dryer with variable fan speed and column thickness. The dryer column has a height of 3.35 m (132 in.), width of 0.61 m (24 in.) and variable thicknesses ranging from 0.30–0.36 m (12–14 in.). In addition, the drying air temperature and air flow rate per volume of grain were varied. An array of thermocouples measured the thermal profile of the corn bed within the dryer. The dryer exhaust was divided into four zones, each 0.83 m (33 in.) tall. Each zone measured incoming air velocity and exhaust temperature and relative humidity. Using these measured values in conjunction with the known ambient conditions, the theoretical amount of moisture removed from each zone was calculated. Corn dryer efficiency and throughput are becoming increasingly important, as it is the second largest cost associated with corn production. Improved farming practices, in conjunction with improved corn genetics, have resulted in increased yields and the ability to grow corn in locations not possible two decades prior. The overarching goal of this research is to help determine the key factors which help to dry corn more efficiently.
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Kim, Moon K., Byeongsoo Lim, and Wing Kam Liu. "Multiscale Elastic Network Model for Macromolecular Machines." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13090.

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In the early year of this century the human genome sequencing project was successfully completed so that we can understand all the human genes and their corresponding protein sequences. Now our interests have naturally moved from genetics to proteomics in which we challenge to elucidate the relationship between functions and structures of proteins. In particular, understanding large conformational changes occurring at molecular machinery systems or protein assemblies have received great attentions. However, it has been rarely studied both experimentally and theoretically because of limitation of experimental setup for capturing real time protein dynamics and computing power, respectively.
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Bagheri, Mostafa, Peiman Naseradinmousavi, and Rasha Morsi. "Experimental and Novel Analytical Trajectory Optimization of a 7-DOF Baxter Robot: Global Design Sensitivity and Step Size Analyses." In ASME 2017 Dynamic Systems and Control Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/dscc2017-5004.

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In this paper, we present a novel nonlinear analytical coupled trajectory optimization of a 7-DOF Baxter manipulator validated through experimental work utilizing global optimization tools. The robotic manipulators used in network-based applications of industrial units and even homes, for disabled patients, spend significant lumped amount of energy and therefore, optimal trajectories need to be generated to address efficiency issues. We here examine both heuristic (Genetics) and gradient based (GlobalSearch) algorithms for a novel approach of “S-Shaped” trajectory (unlike conventional polynomials), to avoid being trapped in several possible local minima along with yielding minimal computational cost, enforcing operational time and torque saturation constraints. The global schemes are utilized in minimizing the lumped amount of energy consumed in a nominal path given in the collision-free joint space except an impact between the robot’s end effector and a target object for the nominal operation. Note that such robots are typically operated for thousands of cycles resulting in a considerable cost of operation. Due to the expected computational cost of such global optimization algorithms, step size analysis is carried out to minimize both the computational cost (iteration) and possibly cost function by finding an optimal step size. Global design sensitivity analysis is also performed to examine the effects of changes of optimization variables on the cost function defined.
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Sarvi, Masoud Nasiri, and M. T. Ahmadian. "Comparison of Deformation Analysis of a Biological Cell Under an Injection Force Using Analytical, Experimental and Finite Element Methods and Artificial Neural Network." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-63791.

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Biological cell injection is a sensitive and important work which is implemented in injection of foreign materials into individual cells. Microinjection is significantly developed in the field of drug discovery and genetics so predicting the behavior of cell in microinjection is remarkably important because a tiny excessive manipulation force can destroy the tissue of the biological cell. There are a few analytical methods available to simulate the cell injection, hence the numerical methods such as FEM are suitable to be used to model the microinjection. In this study, a new spherical super element is presented to model the biological cells and deformation of a specific cell under an external force is performed. The relationship between the injection force and the deformation of biological cell is demonstrated by using super element formulations. For validating the model, results are compared with findings of analytical and experimental methods and an Artificial Neural Network (ANN) model. The advantage of this element is that only a few super elements can predict the static behavior of biological cell in microinjection properly instead of implementing a large number of conventional elements, so using the super element to model the cell can decrease the run time with suitable accuracy.
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Esfandyarpour, Hesaam, and Ronald W. Davis. "Gate-Controlled Microfluidic Chamber With Magnetic Bead for DNA Sequencing-by-Synthesis Technology." In ASME 2007 5th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2007. http://dx.doi.org/10.1115/icnmm2007-30119.

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In this paper we present a novel microfluidic platform for DNA sequencing-by-synthesis methods (e.g. pyrosequencing). The proposed platform is based on the valve-controllable PDMS channel technology with DNA-coated magnetic beads. The encapsulation of the reaction of DNA polymerization in picoliter-sized wells provides for excellent isolation and control for detection. This separation prevents cross-talk amongst neighbor reactors which is one of the most limitations for higher integration of the current technologies. Through application of an external magnetic field the beads can be allocated with better accuracy. In addition this property can help mixing for the reaction. The proposed system is useful for a number of other bio-species detection and sorting templates. This paper illustrates the design and experimental results of a primary template as well as different advantages and potential applications of the Gate-Controlled Magnetic Bead (GCMB) platform in the world of DNA sequencing and genetics.
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Komai, Kenjiro, K. Minoshima, and T. Suezaki. "Genetic algorithms for high-precision reconstructions of three-dimensional topographies using stereo fractographs." In Second International Conference on Experimental Mechanics, edited by Fook S. Chau and Chenggen Quan. SPIE, 2001. http://dx.doi.org/10.1117/12.429626.

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Sarvi, Masoud Nasiri, and M. T. Ahmadian. "Application of a New Spherical Super Element in Predicting the Deformation of Biological Cells in Microinjection." In ASME 2011 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/detc2011-47653.

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Biological cell injection is a sensitive and important work which is implemented in injection of foreign materials into individual cells. Microinjection is significantly developed in the field of drug discovery and genetics so predicting the behavior of cell in microinjection is remarkably important because a tiny excessive manipulation force can destroy the tissue of the biological cell. There are a few analytical methods available to simulate the cell injection, hence the numerical methods such as FEM are suitable to be used to model the microinjection. In this study, a new spherical super element is presented to model the biological cells and deformation of a specific cell under an external force is performed. The relationship between the injection force and the deformation of biological cell is demonstrated by using super element formulations. For validating the model, results are compared with findings of analytical and experimental methods. The advantage of this element is that only a few super elements can predict the static behavior of biological cell in microinjection properly instead of implementing a large number of conventional elements, so using the super element to model the cell can decrease the run time with suitable accuracy.
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Campelo, Felipe, and Moisés Botelho. "Experimental Investigation of Recombination Operators for Differential Evolution." In GECCO '16: Genetic and Evolutionary Computation Conference. New York, NY, USA: ACM, 2016. http://dx.doi.org/10.1145/2908812.2908852.

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Reports on the topic "Genetics, Experimental"

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Amzeri, Achmad, Kaswan Badami, and Gita Pawana. Inheritance of resistance to downy mildew (Peronosclerospora maydis) in crossing of Madura Maize Plant (Zea mays L.). Innovative Scientific Information & Services Network, May 2019. http://dx.doi.org/10.21107/amzeri.2019.1.

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Hybridization of Back cross is one method to get varieties that are resistant to downy mildew. The purpose of this study was to obtain information on inheritance characteristics of downy mildew resistance. This research was conducted at the experiment center of Agro-Technology Study Program of Agriculture Faculty, University of Trunojoyo Madura. Research of Assessment of resistance to Downy Mildew used a randomized block design with 18 treatments (P1, P2, F1, F2, BC1P1 and BC1P2 in three sets of crosses, namely LGL x Mdr-3, T12 x Mdr-1 and E02 x Mdr-2) and three replications so there were 54 experimental units. Identification of polymorphic RAPD markers for endurance to downy mildew through Bulk Segregant Analysis (BSA) was done by amplifying the DNA in the resistant pool and susceptible pool. The random primers used were 120 primers from 6 operon groups, namely OPA, OPB, OPC, OPD, OPF and OPG. The results showed that the inheritance pattern of maize genetic resistance to downy mildew followed a segregation pattern of 3:1 with a degree of dominance between -1 and 0, and was controlled by incomplete partially negative dominant gene. OPC-07 was a marker that was linkage close to the resistance to downy mildew with a genetic distance of 1.9 cM.
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Zhou, Aifen, Kristina Hillesland, Zhili He, Marcin Joachimiak, Grant Zane, Paramvir Dehal, Adam Arkin, et al. Genetic Adaptation to Salt Stress in Experimental Evolution of Desulfovibrio vulgaris Hildenborough. Office of Scientific and Technical Information (OSTI), May 2010. http://dx.doi.org/10.2172/985929.

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Fritz, Dominik Arthur. Genetic Algorithm Based Critical Experiment Design for Uranium Cross Section Validation. Office of Scientific and Technical Information (OSTI), August 2018. http://dx.doi.org/10.2172/1463589.

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Nation, Yakima Indian, Pacific Northwest Laboratory, and Washington Department of Fisheries. Yakima/Klickitat Production Project Preliminary Design Report, Appendix A: Refined Project Goals and Harvest Managment Plan : Experimental Design Plan : Genetic Risk Assessment. Office of Scientific and Technical Information (OSTI), March 1990. http://dx.doi.org/10.2172/920101.

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