Academic literature on the topic 'Genetics engineering'
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Journal articles on the topic "Genetics engineering"
Sprenger, G. A., M. A. Typas, and C. Drainas. "Genetics and genetic engineering ofZymomonas mobilis." World Journal of Microbiology & Biotechnology 9, no. 1 (January 1993): 17–24. http://dx.doi.org/10.1007/bf00656509.
Full textKuchuk, N. V. "Cell genetic engineering: Transmission genetics of plants." Cytology and Genetics 51, no. 2 (March 2017): 103–7. http://dx.doi.org/10.3103/s0095452717020062.
Full textWomack, James E. "Genetic engineering in agriculture: animal genetics and development." Trends in Genetics 3 (January 1987): 65–68. http://dx.doi.org/10.1016/0168-9525(87)90177-6.
Full textKU, In-Hoe. "Ethical Problems of Genetic Engineering and Responsibilities of Geneticists." Korean Journal of Medical Ethics 3, no. 2 (November 2000): 183–97. http://dx.doi.org/10.35301/ksme.2000.3.2.183.
Full textHarvey, J. "Genetic Engineering." Journal of Medical Genetics 30, no. 8 (August 1, 1993): 711–12. http://dx.doi.org/10.1136/jmg.30.8.711-b.
Full textLittle, Peter. "Genetic engineering." Trends in Genetics 5 (1989): 198. http://dx.doi.org/10.1016/0168-9525(89)90078-4.
Full textDorin, Julia R. "Genetic engineering." Trends in Genetics 9, no. 9 (September 1993): 327. http://dx.doi.org/10.1016/0168-9525(93)90254-f.
Full textTangngareng, Tasmim, Irwan Abdullah, Rahman Rahman, and Sawaluddin Sawaluddin. "THE CONSTRUCTION OF HADITH ADDRESSING GENETIC ENGINEERING OF HUMANS." Jurnal Ilmiah Islam Futura 23, no. 1 (June 21, 2023): 20. http://dx.doi.org/10.22373/jiif.v23i1.14716.
Full textShapiro, James A. "LettingEscherichia coliTeach Me About Genome Engineering." Genetics 183, no. 4 (December 2009): 1205–14. http://dx.doi.org/10.1534/genetics.109.110007.
Full textCarroll, Dana. "Genome Engineering With Zinc-Finger Nucleases." Genetics 188, no. 4 (August 2011): 773–82. http://dx.doi.org/10.1534/genetics.111.131433.
Full textDissertations / Theses on the topic "Genetics engineering"
Conradie, E. C. (Elizabeth Cornelia). "Promotor engineering in Saccharomyces cerevisiae for transcriptional control under different physiological conditions." Thesis, Stellenbosch : University of Stellenbosch, 2011. http://hdl.handle.net/10019.1/16512.
Full textENGLISH ABSTRACT: To manipulate recombinant microorganisms for industrial processes, controllable genetic systems are needed that can coordinate expression of recombinant metabolic pathways. All components are sensitive to change and thus putative targets for modification and genetic elements and regulatory systems need to be understood and determined. Central in gene regulation is the transcription activators that mediate gene transcription mechanisms by binding to promoters in response to environmental signals. Promoter engineering entails the modification of transcription factors and their target promoters. In this study, a metabolic control system in Saccharomyces cerevisiae was constructed that would allow induction in response to physiological environment, specifically hypoxia and low temperature conditions. Two approaches were undertaken to find such a system. Firstly, a bi-directional reporter gene cloning vector was designed to search for novel hypoxiainducible promoters. Secondly, a transcription regulatory circuit was built, consisting of an inducible transcription regulator and promoter with a reporter gene through which it mediates transcription. Advantage was taken of the modular nature of proteins and functional domains originating from different transcriptional proteins were combined. A search for promoter elements sensitive to hypoxia from a S. cerevisiae genomic DNA (gDNA) library, using a bi-directional cloning vector, did not yield highly inducible promoters. It was concluded that a multitude of signals overlap, rendering genetic induction difficult to control. A synthetic regulatory system would minimize the impact of these multiple interactions. Such a genetic circuit was constructed, consisting of a chimeric transcription activator and a target fusion promoter. The chimeric transcription activator consisted of the GAL4 DNA binding domain, ADR1 TADIII transactivation domain and three domains of the MGA2 regulatory protein. The functional domains of Mga2p responsible for unregulated expression (at high basal levels) under both aerobic and hypoxia conditions were located, as well as a further upregulation under low temperature, and were mapped to the Nterminal and mid-Mga2p regions. A target fusion promoter consisting of a partial GAL10/1 promoter sequence and a Trichoderma reesei core xyn2 promoter were constructed as target for this chimeric transactivator. This synthetic promoter was fused to the T. reesei xyn2 open reading frame encoding for a readily assayable β-xylanase activity. Both the chimeric transactivator and fusion promoter-reporter gene cassettes were expressed from the same episomal plasmid, named pAR. Transformed into S. cerevisiae Y294, this regulatory system induced transcription under aerobic and hypoxia conditions. Furthermore, the reporter gene expression was upregulated by the chimeric transactivator at low temperatures. The chimeric transactivator mediated a seven-fold induction of the reporter gene under aerobic conditions in S. cerevisiae Y294 when transformed with plasmid AR. A two- to three-fold induction at 23ºC was reported under anaerobic conditions, relative to a reference strain expressing a transcription activator without the Mga2p domains. At 30ºC, a two- to three-fold induction under aerobic conditions and similar induction under oxygen-limited conditions were observed. Replacing the reporter gene with your favorite gene (for example a recombinant enzyme) and incorporating such a pAR system into a recombinant yeast should induce expression of the chosen gene under low temperatures, both aerobic and anaerobically (thus creating a controllable system). The system also has wider application in identifying other transcription factors’ signal-sensitive domains. The design of this system provides the ability to add a linker to a transactivator and to either create specific signal sensitivity or relieve the regulator of its signal dependence. It creates an easy system for assessing other transactivators and their domains with unknown functions and thus provides a ”workhorse and prospector in one”.
AFRIKAANSE OPSOMMING: Vir die manipulering van rekombinante mikroörganismes vir industriële prosesse word beheerbare genetiese stelsels benodig om gekoördineerde uitdrukking van rekombinante metaboliese weë teweeg te bring. Alle komponente van sulke stelsels is sensitief vir verandering en genetiese elemente en reguleerbare sisteme moet dus deeglik verstaan of bepaal word. Sentraal tot geenregulering is die transkripsie-aktiveerders wat geentranskripsie beheer deur aan promoters te bind in reaksie op eksterne omgewingsfaktore. Promotoringenieurswese behels wysigings van transkripsiefaktore en hul teikenpromotors. In hierdie studie is 'n genetiese beheerstelsel vir Saccaromyces cerevisiae ontwikkel wat induksie in reaksie tot spesifieke fisiologiese omgewingreaksies, naamlik hipoksie- en lae temperatuur, toelaat. Twee benaderings is gevolg: eerstens is ‘n tweerigting verklikker-geen vektor ontwikkel en gebruik om vir unieke induseerbare hipoksie-promoters te soek. Tweedens is ‘n transkripsie reguleringstelsel gebou wat uit ‘n induseerbare transkripsiereguleerder and promotor met ‘n verklikkergeen bestaan, waardeur transkripsie bemiddel kan word. Hierdie benadering benut die modulêre onderbou van proteïene en funksionele domeine afkomstig vanaf verskillende transkripsiefaktore is gekombineer. 'n Soektog na hipoksie-sensitiewe promotors vanuit 'n Saccharomyces cerevisiae-genoom- DNA (gDNA), deur van ‘n tweerigting verklikker-vektor gebruik te maak, het ongelukkig nie hoogs-induseerbare promotors opgelewer nie. Die gevolgtrekking was dat ‘n veelvoud van seine met mekaar oorvleuel en die beheer van genetiese induksie dus bemoeilik. Die ontwikkeling van ‘n sintetiese regulering-sisteem kan die impak van die veelvuldige interaksies verminder. Vir dié doel is ‘n sintetiese reguleringstelsel ontwerp, bestaande uit ‘n chimeriese transkripsie-aktiveerder met ‘n teiken fusie-promotor. Die chimeriese transaktiveerder bestaan uit die GAL4 DNA bindingsdomein, die ADR1 TAD III transaktiveringsdomein en drie domeine van die Mga2 reguleringsproteïen. In die studie is die funksionele domeins van Mga2p betrokke by lae temperatuur-respons en ongereguleerde uitdrukking (teen hoë basale vlakke) onder beide aërobiese en anaërobiese toestande aangedui en is tot die N-terminaal en middel-Mga2p areas gekarteer. ‘n Teiken-fusie-promoter, bestaande uit 'n gedeeltelike GAL1/10 DNA promotoropeenvolging en ‘n Trichoderma reesei kern xyn2-promoter, is as teiken vir hierdie chimeriese transaktiveerder saamgestel. Hierdie sintetiese promotor is aan die T. reesei xyn2 oopleesraam, wat vir ‘n maklik meetbare β-xylanase aktiwiteit kodeer, gekoppel. Beide die chimeriese transaktiveerder and fusie-promoter-verklikker-geenkaset word vanaf dieselfde episomale plasmied, bekend as pAR, uitgedruk. Hierdie reguleringsisteem induseer transkripsie onder aërobiese en hipoksie toestande in S. cerevisiae Y294. Verder word die verklikkergeen se uitdrukking deur die chimeriese transaktiveerder by lae temperature verhoog. Die chimeriese transaktiveerder induseer ‘n sewe-voudige induksie van die verklikkergeen onder aërobiese toestande by 23ºC vanaf die pAR-stelsel in S. cerevisiae Y294. ‘n Twee- tot drie-voudige induksie teen 23ºC is onder hipoksie toestande gevind, relatief tot induksievlakke van ‘n verwysingstam met ‘n transaktiveerder sonder die Mga2 domeine. By 30ºC is ‘n twee- tot drie-voudige induksie onder aërobiese en lae suurstofvlakke waargeneem. Deur die verklikker geen met ‘n jou-gunsteling-geen te vervang (bv. ‘n rekombinante ensiem) en so 'n pAR-sisteem in ‘n rekombinante gis te inkorporeer, word uitdrukking onder lae temperature onder beide aërobiese- en anaërobiese toestande geïnduseer (en sodoende word ‘n reguleerbare sisteem geskep). Die sisteem het wyer toepassing om sein-sensitiewe domeine van ander transkripsiefaktore te identifiseer. Die ontwerp van die stelsel maak dit moontlik om 'n skakel tot die transaktiveerder by te voeg wat óf sensitiwiteit tot 'n spesifieke sein skep, óf die reguleerder vanaf seinafhanklikheid verlos. So word ‘n bruikbare stelsel vir die bestudering van ander transaktivators en hul domeine met onbekende funksie geskep – ‘n “werksesel en prospekteerder in een”.
Wilsher, Julie Ann. "Protein engineering of chymosin." Thesis, Birkbeck (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.300804.
Full textHill, Philip John. "PCR based gene engineering." Thesis, University of Nottingham, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317040.
Full textSutherland, John David. "Genetic engineering of penicillin biosynthesis." Thesis, University of Oxford, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.253132.
Full textHilyard, Katherine L. "Protein engineering of antibody combining sites." Thesis, University of Oxford, 1991. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.291278.
Full text黃雅誼 and Nga-yi Queenie Wong. "DNA engineering utilizing thymidylate synthase A (thyA) selection system in Escherichia coli." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B31226851.
Full textZainuddin. "Genetic transformation of wheat (Triticum aestivum L.)." Title page, Contents and Abstract only, 2000. http://web4.library.adelaide.edu.au/theses/09APSP/09apspz21.pdf.
Full textau, dweston@ncwa com, and Delys Eleanor Weston. "Democracy and political economy of genetic engineering." Murdoch University, 2007. http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20070327.143205.
Full textMacKenzie, Donald J. "Molecular characterization of potato virus S and genetic engineering of virus resistant plants." Thesis, University of British Columbia, 1990. http://hdl.handle.net/2429/30622.
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Biochemistry and Molecular Biology, Department of
Graduate
Purohit, Shri Kant. "Analysis of nodulin-44 gene of soybean." Thesis, McGill University, 1987. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=66088.
Full textBooks on the topic "Genetics engineering"
Wexler, Barbara. Genetics and genetic engineering. 2nd ed. Detroit, MI: Thomson/Gale Group, 2006.
Find full textGenetics and genetic engineering. 2nd ed. Farmington Hills, Mich: Gale Cengage Learning, 2015.
Find full textYount, Lisa. Genetics and genetic engineering. New York: Facts on File, 1997.
Find full textSydney, Brenner, and Miller Jeffrey H, eds. Encyclopedia of genetics. San Diego, Calif: Academic, 2002.
Find full textLakra, W. S. Genetics, genetic engineering and biotechnology in fisheries. New Delhi: Indian Council of Agricultural Research, 2013.
Find full textYount, Lisa. Modern genetics: Engineering life. New York NY: Facts on File, 2006.
Find full textBryan, Jenny. Genetic engineering. New York: Thomson Learning, 1995.
Find full textBryan, Jenny. Genetic engineering. New York: Thomson Learning, 1995.
Find full textL, Oxender Dale, and Fox C. Fred 1937-, eds. Protein engineering. New York: Liss, 1987.
Find full textTudge, Colin. The day before yesterday: Five million years of human history. London: Pimlico, 1996.
Find full textBook chapters on the topic "Genetics engineering"
Alderson, Pauline, and Martin Rowland. "Genetics, Cell Division and Genetic Engineering." In Making Use of Biology for GCSE, 305–20. London: Macmillan Education UK, 1989. http://dx.doi.org/10.1007/978-1-349-10062-0_25.
Full textAlderson, Pauline, and Martin Rowland. "Genetics, Cell Division, DNA and Genetic Engineering." In Making Use of Biology, 313–33. London: Macmillan Education UK, 1995. http://dx.doi.org/10.1007/978-1-349-13563-9_25.
Full textWurtzel, Eleanore T. "Rice Genetics: Engineering Vitamin A." In Encyclopedia of Genetics, 668–71. New York: Routledge, 2014. http://dx.doi.org/10.4324/9781315073972-98.
Full textSchmid, Jochen, Ulf Stahl, and Vera Meyer. "Genetic and Metabolic Engineering in Filamentous Fungi." In Physiology and Genetics, 377–92. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-00286-1_18.
Full textBoerjan, W., H. Meyermans, C. Chen, J. C. Leplé, J. H. Christensen, J. Van Doorsselaere, M. Baucher, et al. "Genetic Engineering of Lignin Biosynthesis in Poplar." In Somatic Cell Genetics and Molecular Genetics of Trees, 81–88. Dordrecht: Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-011-3983-0_11.
Full textTrolinder, Norma L. "Genetic Engineering of Cotton." In Genetics and Genomics of Cotton, 187–207. New York, NY: Springer US, 2009. http://dx.doi.org/10.1007/978-0-387-70810-2_8.
Full textLiu, Yanping, and Yongzhong Tang. "Enterprise Organizational Genetics Research." In Enterprise Organization Engineering, 225–51. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-1094-6_12.
Full textRauch, Peter J. G., Oscar P. Kuipers, Roland J. Siezen, and Willem M. De Vos. "Genetics and Protein Engineering of Nisin." In Bacteriocins of Lactic Acid Bacteria, 223–49. Boston, MA: Springer US, 1994. http://dx.doi.org/10.1007/978-1-4615-2668-1_6.
Full textEbert, P. R., M. Altschuler, and A. E. Clarke. "Molecular Genetics of Self-Incompatibility in Flowering Plants." In Genetic Engineering, 171–81. Boston, MA: Springer US, 1989. http://dx.doi.org/10.1007/978-1-4615-7084-4_10.
Full textMeyer, Peter. "Engineering of Novel Flower Colours." In Genetics and Breeding of Ornamental Species, 285–307. Dordrecht: Springer Netherlands, 1991. http://dx.doi.org/10.1007/978-94-011-3296-1_15.
Full textConference papers on the topic "Genetics engineering"
"Site-specific genetic engineering in cereals – principles and applications." In Plant Genetics, Genomics, Bioinformatics, and Biotechnology. Novosibirsk ICG SB RAS 2021, 2021. http://dx.doi.org/10.18699/plantgen2021-117.
Full textMorgan, Jeffrey R. "Genetic Strategies for Tissue Engineering." In ASME 1996 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1996. http://dx.doi.org/10.1115/imece1996-1165.
Full textTurner, Charles H. "How Microimaging Technology Is Transforming the Field of Skeletal Genetics." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-33057.
Full text"New efficient gene promoters from Stellaria media for plant genetic engineering." In Current Challenges in Plant Genetics, Genomics, Bioinformatics, and Biotechnology. Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences Novosibirsk State University, 2019. http://dx.doi.org/10.18699/icg-plantgen2019-42.
Full textPhillips, Winfred M. "Bioengineering: From Mechanics and Devices to Tissue Engineering and Genetics." In ASME 2001 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2001. http://dx.doi.org/10.1115/imece2001/ts-23402.
Full textTsourkas, Philippos K., and Boris Rubinsky. "Laplace’s Equation, Genetic Algorithms, and Evolution." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-32658.
Full textTurner, Charles H., and Alexander G. Robling. "Genetic Effects on Skeletal Mechanosensitivity in Mice." In ASME 2002 International Mechanical Engineering Congress and Exposition. ASMEDC, 2002. http://dx.doi.org/10.1115/imece2002-32596.
Full textMitchell, L. A., and J. D. Boeke. "Genetics from scratch: designing and building synthetic eukaryotic chromosomes." In IET/SynbiCITE Engineering Biology Conference. Institution of Engineering and Technology, 2016. http://dx.doi.org/10.1049/cp.2016.1223.
Full textSebaa, K., N. Henini, A. Tlemcani, and H. Nouri. "Restructuration of distribution power system using Genetics Algorithms." In 2015 50th International Universities Power Engineering Conference (UPEC). IEEE, 2015. http://dx.doi.org/10.1109/upec.2015.7339834.
Full textMarciniak, Malgorzata, and Rahul Chowdhury. "Optimal geometry of solar cells with genetics algorithm." In Physics, Simulation, and Photonic Engineering of Photovoltaic Devices VIII, edited by Alexandre Freundlich, Masakazu Sugiyama, and Laurent Lombez. SPIE, 2019. http://dx.doi.org/10.1117/12.2510943.
Full textReports on the topic "Genetics engineering"
Gur, Ilan. Biologically Diverse Genetic Engineering Platform. Office of Scientific and Technical Information (OSTI), March 2020. http://dx.doi.org/10.2172/1607790.
Full textAllen, J., and T. Slezak. Genetic Engineering Workshop Report, 2010. Office of Scientific and Technical Information (OSTI), November 2010. http://dx.doi.org/10.2172/1016982.
Full textWeil, Clifford F., Anne B. Britt, and Avraham Levy. Nonhomologous DNA End-Joining in Plants: Genes and Mechanisms. United States Department of Agriculture, July 2001. http://dx.doi.org/10.32747/2001.7585194.bard.
Full textPerl, Avichai, Bruce I. Reisch, and Ofra Lotan. Transgenic Endochitinase Producing Grapevine for the Improvement of Resistance to Powdery Mildew (Uncinula necator). United States Department of Agriculture, January 1994. http://dx.doi.org/10.32747/1994.7568766.bard.
Full textHo, N. W. Y. Genetic engineering of sulfur-degrading Sulfolobus. Office of Scientific and Technical Information (OSTI), January 1991. http://dx.doi.org/10.2172/6253123.
Full textHo, N. Genetic engineering of sulfur-degrading Sulfolobus. Office of Scientific and Technical Information (OSTI), January 1990. http://dx.doi.org/10.2172/5922005.
Full textRuffing, Anne, Christine Alexandra Trahan, and Howland D. T. Jones. Genetic engineering of cyanobacteria as biodiesel feedstock. Office of Scientific and Technical Information (OSTI), January 2013. http://dx.doi.org/10.2172/1088046.
Full textWalsh, Nahid S. Genetic Engineering of Single-Domain Magnetic Bacteria. Fort Belvoir, VA: Defense Technical Information Center, September 1992. http://dx.doi.org/10.21236/ada256186.
Full textTombs, Michael P. Biotechnology and Genetic Engineering Reviews. Volume 10. Fort Belvoir, VA: Defense Technical Information Center, December 1992. http://dx.doi.org/10.21236/ada266433.
Full textKlopfenstein, N. B., Y. W. Chun, M. S. Kim, M. A. Ahuja, M. C. Dillon, R. C. Carman, and L. G. Eskew. Micropropagation, genetic engineering, and molecular biology of Populus. Ft. Collins, CO: U.S. Department of Agriculture, Forest Service, Rocky Mountain Forest and Range Experiment Station, 1997. http://dx.doi.org/10.2737/rm-gtr-297.
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