Academic literature on the topic 'Genetics and genomics/functional genomics'
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Journal articles on the topic "Genetics and genomics/functional genomics"
Nagy, László G., Zsolt Merényi, Botond Hegedüs, and Balázs Bálint. "Novel phylogenetic methods are needed for understanding gene function in the era of mega-scale genome sequencing." Nucleic Acids Research 48, no. 5 (January 16, 2020): 2209–19. http://dx.doi.org/10.1093/nar/gkz1241.
Full textBofkin, L., and S. Whelan. "Comparative genomics: Functional needles in a genomic haystack." Heredity 92, no. 5 (April 26, 2004): 363–64. http://dx.doi.org/10.1038/sj.hdy.6800429.
Full textPenn, Raymond B., Victor E. Ortega, and Eugene R. Bleecker. "A Roadmap to functional genomics." Physiological Genomics 30, no. 1 (June 2007): 82–88. http://dx.doi.org/10.1152/physiolgenomics.00010.2007.
Full textSoppa, J., A. Baumann, M. Brenneis, M. Dambeck, O. Hering, and C. Lange. "Genomics and functional genomics with haloarchaea." Archives of Microbiology 190, no. 3 (May 21, 2008): 197–215. http://dx.doi.org/10.1007/s00203-008-0376-4.
Full textDeng, Youping, Hongwei Wang, Ryuji Hamamoto, David Schaffer, and Shiwei Duan. "Functional Genomics, Genetics, and Bioinformatics." BioMed Research International 2015 (2015): 1–3. http://dx.doi.org/10.1155/2015/184824.
Full textLudwig, Kerstin U., and Malte Spielmann. "Functional genomics meets human genetics." Medizinische Genetik 34, no. 4 (November 29, 2022): 259–60. http://dx.doi.org/10.1515/medgen-2022-2160.
Full textCoram, Tristan E., Nitin L. Mantri, Rebecca Ford, and Edwin C. K. Pang. "Functional genomics in chickpea: an emerging frontier for molecular-assisted breeding." Functional Plant Biology 34, no. 10 (2007): 861. http://dx.doi.org/10.1071/fp07169.
Full textBurton, Jeanne L., and Guilherme J. M. Rosa. "Physiological genomics special issue on animal functional genomics." Physiological Genomics 28, no. 1 (December 2006): 1–4. http://dx.doi.org/10.1152/physiolgenomics.00220.2006.
Full textGonzález-Serna, David, Gonzalo Villanueva-Martin, Marialbert Acosta-Herrera, Ana Márquez, and Javier Martín. "Approaching Shared Pathophysiology in Immune-Mediated Diseases through Functional Genomics." Genes 11, no. 12 (December 9, 2020): 1482. http://dx.doi.org/10.3390/genes11121482.
Full textRouthier, Etienne, and Julien Mozziconacci. "Genomics enters the deep learning era." PeerJ 10 (June 24, 2022): e13613. http://dx.doi.org/10.7717/peerj.13613.
Full textDissertations / Theses on the topic "Genetics and genomics/functional genomics"
Burnham, Katie. "Functional genomics of the sepsis response." Thesis, University of Oxford, 2017. http://ora.ox.ac.uk/objects/uuid:cb98af40-1b66-4966-a643-ae8dfec2c122.
Full textBlischak, John David. "Investigating susceptibility to tuberculosis using functional genomics approaches." Thesis, The University of Chicago, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=10238063.
Full textA major goal of human genetics is to characterize the role of genetic variation on complex, polygenic phenotypes. With the discovery from genome-wide association studies (GWAS) that many associated variants have a small effect size and are located in non-coding regions of the genome, there has been a large effort to collect functional genomics data. The hope is that a better understanding of how the genome functions in diverse developmental states and environments will provide insight into the context-specific activity of associated non-coding variants. My research applies this paradigm to the complex phenotype of susceptibility to develop tuberculosis (TB). It has been estimated that 10% of individuals infected with Mycobacterium tuberculosis (MTB) progress to active disease. Despite being heritable, very few genetic variants have been associated with susceptibility to TB. For my studies, I use RNA sequencing (RNA-seq) to interrogate genome-wide transcript levels in in vitro cellular models. In Chapter 2, I use a joint Bayesian model to identify genes which are differentially expressed in macrophages only after infection with MTB and related mycobacteria, but not other bacterial pathogens. In Chapter 3, I build a support vector machine model to classify individuals as susceptible or resistant to TB based on the gene expression levels in their dendritic cells. In Chapter 4, I characterize the technical variation introduced by batch processing of single-cell RNA-seq (scRNA-seq) and propose an effective study design that accounts for technical variation while minimizing replication. In addition to providing insight into the genes important for the innate immune response to MTB infection, my work is informative for the design and analysis of future functional genomics experiments. (Note: Supplementary tables are provided in a .zip file available online. Captions for the tables are provided within the dissertation.)
Moustafa, Ahmed. "Evolutionary and functional genomics of photosynthetic eukaryotes." Diss., University of Iowa, 2009. https://ir.uiowa.edu/etd/311.
Full textMizrachi, Eshchar. "Functional genomics and systems genetics of cellulose biosynthesis in Eucalyptus." Diss., University of Pretoria, 2013. http://hdl.handle.net/2263/79771.
Full textThesis (PhD)--University of Pretoria, 2013.
Wood and Fibre Molecular Genetics (WFMG) Programme
National Research Foundation (NRF)
Technology and Human Resources for Industry Programme (THRIP)
Genetics
PhD
Unrestricted
Radhakrishnan, Jayachandran. "Functional genomics of severe sepsis and septic shock." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:2b2afd65-82e0-4847-b7ae-960635b7e884.
Full textShao, Diane Donghui. "Functional Genomics Approaches to Identify and Characterize Oncogenic Signaling." Thesis, Harvard University, 2013. http://dissertations.umi.com/gsas.harvard:11076.
Full textSteinberg, Julia. "Functional genomics analyses of neuropsychiatric and neurodevelopmental disorders." Thesis, University of Oxford, 2014. http://ora.ox.ac.uk/objects/uuid:e47d1ac2-de92-47d8-864b-dac0bf6669e8.
Full textMiller, Michael Ryan. "Functional Genomics of Nervous System Development and Disease." Thesis, University of Oregon, 2011. http://hdl.handle.net/1794/12102.
Full textThe goal of functional genomics is to elucidate the relationship between an organism's genotype and phenotype. A key characteristic of functional genomics is the use of genome-wide approaches as opposed to more traditional single-gene approaches. Genome-wide expression profiling is used to investigate the dynamic properties of transcriptomes, provides insights into how biological functions are encoded in genomes, and is an important technique in functional genomics. This dissertation describes the use of genome-wide expression profiling and other functional genomics techniques to address a variety of biological questions related to development and disease of the nervous system. Our results reveal novel and important insights into nervous system development and disease and demonstrate the power of functional genomics approaches for the study of nervous system biology. This dissertation also describes a novel technique called TUtagging that facilitates cell type-specific RNA isolation from intact complex tissues. The isolation of RNA from specific cell types within a complex tissue is a major limiting factor in the application of genome-wide expression profiling, and TU-tagging can be used to address a wide array of interesting and important biological questions. This dissertation includes previously published and unpublished co-authored material.
Committee in charge: Dr. John Postlethwait, Chair; Dr. Chris Doe, Advisor; Dr. Bruce Bowerman, Member; Dr. Patrick Phillips, Member; Dr. Tom Stevens, Outside Member
Butler, Heather. "Functional genomics : analysis of polytene region 38 of Drosophila melanogaster." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0016/MQ55041.pdf.
Full textBarona, Gómez Francisco. "Functional and structural genomics of amino acid metabolism in Streptomyces coelicolor." Thesis, University of Warwick, 2003. http://wrap.warwick.ac.uk/59424/.
Full textBooks on the topic "Genetics and genomics/functional genomics"
Town, Christopher. Functional genomics. Dordrecht: Springer Science, 2002.
Find full textErich, Grotewold, ed. Plant functional genomics. Totowa, N.J: Humana Press, 2003.
Find full textPevsner, Jonathan. Bioinformatics and Functional Genomics. New York: John Wiley & Sons, Ltd., 2005.
Find full textBioinformatics and functional genomics. Hoboken, NJ: Wiley-Liss, 2004.
Find full textMarsupial genetics and genomics. Dordrecht: Springer, 2010.
Find full textBioinformatics and functional genomics. 2nd ed. Hoboken, N.J: Wiley, 2009.
Find full text1951-, Stacey Gary, ed. Genetics and genomics of soybean. New York: Springer, 2008.
Find full textBurnap, Robert. Functional Genomics and Evolution of Photosynthetic Systems. Dordrecht: Springer Science +Business Media B.V., 2012.
Find full textPhenotypic variation: Exploration and functional genomics. Oxford: Oxford University Press, 2010.
Find full textThe handbook of plant functional genomics: Concepts and protocols. Weinheim: Wiley-Blackwell, 2008.
Find full textBook chapters on the topic "Genetics and genomics/functional genomics"
Mondal, Tapan Kumar. "Functional Genomics." In Tea: Genome and Genetics, 229–308. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-15-8868-6_8.
Full textAllan, Andrew C., Ross Crowhurst, Andrew Gleave, Richard Newcomb, and Robert Schaffer. "Apple Functional Genomics." In Genetics and Genomics of Rosaceae, 121–42. New York, NY: Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-77491-6_6.
Full textNowrousian, M., J. C. Dunlap, and M. A. Nelson. "Functional Genomics in Fungi." In Genetics and Biotechnology, 115–28. Berlin, Heidelberg: Springer Berlin Heidelberg, 2004. http://dx.doi.org/10.1007/978-3-662-07426-8_7.
Full textBlaby, Ian K., and Crysten E. Blaby-Haas. "Genomics and Functional Genomics in Chlamydomonas reinhardtii." In Chlamydomonas: Molecular Genetics and Physiology, 1–26. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-66365-4_1.
Full textAbbott, Albert G., Bryon Sosinski, and Ariel Orellana. "Functional Genomics in Peach." In Genetics and Genomics of Rosaceae, 259–75. New York, NY: Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-77491-6_12.
Full textFoucher, Fabrice. "Functional Genomics in Rose." In Genetics and Genomics of Rosaceae, 381–92. New York, NY: Springer New York, 2009. http://dx.doi.org/10.1007/978-0-387-77491-6_18.
Full textZhang, Jisen, Marvellous Zhou, James Walsh, Lin Zhu, Youqiang Chen, and Ray Ming. "Sugarcane Genetics and Genomics." In Sugarcane: Physiology, Biochemistry, and Functional Biology, 623–43. Chichester, UK: John Wiley & Sons Ltd, 2013. http://dx.doi.org/10.1002/9781118771280.ch23.
Full textLarkin, M. J., L. A. Kulakov, and C. C. R. Allen. "Rhodococcus: Genetics and Functional Genomics." In Handbook of Hydrocarbon and Lipid Microbiology, 1345–53. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-540-77587-4_94.
Full textCoulouarn, Cédric, and Snorri S. Thorgeirsson. "Integrative and Functional Genomics of HCC." In Molecular Genetics of Liver Neoplasia, 221–40. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-6082-5_12.
Full textWalker, Scott S., Chad Houseweart, and Teresa J. Kenney. "Genetic Footprinting for Bacterial Functional Genomics." In Prokaryotic Genomics, 90–101. Basel: Birkhäuser Basel, 2003. http://dx.doi.org/10.1007/978-3-0348-8963-6_8.
Full textConference papers on the topic "Genetics and genomics/functional genomics"
"Plant cell wall as a target for functional genomics." In Plant Genetics, Genomics, Bioinformatics, and Biotechnology. Novosibirsk ICG SB RAS 2021, 2021. http://dx.doi.org/10.18699/plantgen2021-068.
Full text"Functional characteristics of EST-SSR markers in Pinus sylvestris L." In Plant Genetics, Genomics, Bioinformatics, and Biotechnology. Novosibirsk ICG SB RAS 2021, 2021. http://dx.doi.org/10.18699/plantgen2021-075.
Full text"Functional analysis of Solanum lycopersicum L. MADS-box gene SlMADS5." In Plant Genetics, Genomics, Bioinformatics, and Biotechnology. Novosibirsk ICG SB RAS 2021, 2021. http://dx.doi.org/10.18699/plantgen2021-140.
Full text"Functional characterization of papain-like cysteine proteases genes in rice." In Plant Genetics, Genomics, Bioinformatics, and Biotechnology. Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, 2019. http://dx.doi.org/10.18699/plantgen2019-124.
Full text"Functional characterization of genes with circadian expression patterns in common wheat." In Plant Genetics, Genomics, Bioinformatics, and Biotechnology. Novosibirsk ICG SB RAS 2021, 2021. http://dx.doi.org/10.18699/plantgen2021-098.
Full text"Structural and functional characterization of transcription factor binding sites: from bioinformatics to hormone biosensors." In Plant Genetics, Genomics, Bioinformatics, and Biotechnology. Novosibirsk ICG SB RAS 2021, 2021. http://dx.doi.org/10.18699/plantgen2021-038.
Full text"Bioresource collections of vegetable plants as an initial material for breeding cultivars with high biochemical value and for obtaining functional foods." In Plant Genetics, Genomics, Bioinformatics, and Biotechnology. Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, 2019. http://dx.doi.org/10.18699/plantgen2019-056.
Full text"Polyphenol oxidase gene family in barley (Hordeum vulgare L.): structural organization and functional activity of the genes in respect to black grain pigment formation." In Plant Genetics, Genomics, Bioinformatics, and Biotechnology. Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, 2019. http://dx.doi.org/10.18699/plantgen2019-104.
Full text"Functional characterization of Stagonospora nodorum necrotrophic effectors." In Current Challenges in Plant Genetics, Genomics, Bioinformatics, and Biotechnology. Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences Novosibirsk State University, 2019. http://dx.doi.org/10.18699/icg-plantgen2019-21.
Full text"The protective functions of progesterone system of hormonal regulation in higher plants." In Plant Genetics, Genomics, Bioinformatics, and Biotechnology. Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, 2019. http://dx.doi.org/10.18699/plantgen2019-171.
Full textReports on the topic "Genetics and genomics/functional genomics"
Mawassi, Munir, Baozhong Meng, and Lorne Stobbs. Development of Virus Induced Gene Silencing Tools for Functional Genomics in Grapevine. United States Department of Agriculture, July 2013. http://dx.doi.org/10.32747/2013.7613887.bard.
Full textRon, Eliora, and Eugene Eugene Nester. Global functional genomics of plant cell transformation by agrobacterium. United States Department of Agriculture, March 2009. http://dx.doi.org/10.32747/2009.7695860.bard.
Full textSessa, Guido, and Gregory Martin. A functional genomics approach to dissect resistance of tomato to bacterial spot disease. United States Department of Agriculture, January 2004. http://dx.doi.org/10.32747/2004.7695876.bard.
Full textAvni, Adi, and Kirankumar S. Mysore. Functional Genomics Approach to Identify Signaling Components Involved in Defense Responses Induced by the Ethylene Inducing Xyalanase Elicitor. United States Department of Agriculture, December 2009. http://dx.doi.org/10.32747/2009.7697100.bard.
Full textAbbott, Albert G., Doron Holland, Douglas Bielenberg, and Gregory Reighard. Structural and Functional Genomic Approaches for Marking and Identifying Genes that Control Chilling Requirement in Apricot and Peach Trees. United States Department of Agriculture, September 2009. http://dx.doi.org/10.32747/2009.7591742.bard.
Full textMawassi, Munir, and Valerian V. Dolja. Role of the viral AlkB homologs in RNA repair. United States Department of Agriculture, June 2014. http://dx.doi.org/10.32747/2014.7594396.bard.
Full textKlein, Eric, and Yaw Nyame. The genetics and genomics of prostate cancer. BJUI Knowledge, July 2019. http://dx.doi.org/10.18591/bjuik.0152.
Full textLennie, Peter. Facilities and Equipment for Genomics/Comparative Functional Genomics at New York University. Office of Scientific and Technical Information (OSTI), June 2006. http://dx.doi.org/10.2172/898062.
Full textYuen, Gary, Serge Edme, Gautam Sarath, Nathan Palmer, Satyanarayana Tatineni, and Robert Mitchell. Genetics and Genomics of Pathogen Resistance in Switchgrass. Office of Scientific and Technical Information (OSTI), December 2020. http://dx.doi.org/10.2172/1783170.
Full textLers, Amnon, and Gan Susheng. Study of the regulatory mechanism involved in dark-induced Postharvest leaf senescence. United States Department of Agriculture, January 2009. http://dx.doi.org/10.32747/2009.7591734.bard.
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