Dissertations / Theses on the topic 'Genetic epidemiology'
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WOO, DANIEL. "GENETIC EPIDEMIOLOGY OF INTRACEREBRAL HEMORRHAGE." University of Cincinnati / OhioLINK, 2004. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1099665780.
Full textAhmadipour, Nooshin. "Genetic epidemiology of tuberculosis." Thesis, McGill University, 2002. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=78234.
Full textObjective. To examine the effect of several candidate genes, including natural resistance associated macrophage protein 1 (NRAMP1), vitamin D receptor (VDR), surfactant proteins (SFTPA1), and mannose-binding lectin (MBL), and also to assess the effect of several risk factors on their association with tuberculosis. The other objectives were to test for mode of inheritance and also to estimate the relative risks of disease for different genotypes.
Methods. A prospective case-parental control study was conducted. Ninety-five nuclear families were selected from an existing database of families with tuberculosis in Ethiopia. Each family consisted of one affected child and two parents. The primary outcome was transmission/nontransmission of alleles from parents to affected offspring.
Results. The transmission disequilibrium test showed that marker SFTPA1-294 was significantly associated with the outcome (chi 2 = 4.297; p = 0.038). When other risk factors such as age, sex, ethnicity, certain symptoms or other genes were allowed to modify the transmission probabilities in a logistic regression model, several other markers were found to be significantly associated with the outcome.
Conclusions. Despite the limitations of this study, this thesis provided evidence for inheritance of susceptibility to tuberculosis in Hadiayan families in Ethiopia. To confirm the findings in this thesis, it would be useful to conduct similar research in populations with different ethnic origins, where genetic and environmental exposures can be examined and compared.
Rahman, Al-Amin Proton. "Genetic epidemiology of psoriatic arthritis." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape9/PQDD_0004/MQ46117.pdf.
Full textWiklund, Fredrik. "Genetic epidemiology of prostate cancer." Doctoral thesis, Umeå : Univ, 2004. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-281.
Full textKeen, Richard William. "Genetic epidemiology of postmenopausal osteoporosis." Thesis, King's College London (University of London), 2000. https://kclpure.kcl.ac.uk/portal/en/theses/genetic-epidemiology-of-postmenopausal-osteoporosis(15d66e32-f0bb-4b51-9e82-60646699d319).html.
Full textWhong-Barr, Michael. "Biomedical ethics and genetic epidemiology." Thesis, Durham University, 2004. http://etheses.dur.ac.uk/2817/.
Full textHolberg, Catharine Jean 1944. "Genetic epidemiology of asthma phenotypes." Diss., The University of Arizona, 1998. http://hdl.handle.net/10150/565581.
Full textKho, Pik Fang. "Genetic epidemiology of endometrial cancer." Thesis, Queensland University of Technology, 2021. https://eprints.qut.edu.au/211383/1/Pik%20Fang_Kho_Thesis.pdf.
Full textMedland, Sarah. "The genetic epidemiology of behavioural laterality /." [St. Lucia, Qld.], 2005. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe19204.pdf.
Full textSpinka, Christine Marie. "Gene-environment interactions in genetic epidemiology." Texas A&M University, 2004. http://hdl.handle.net/1969.1/1399.
Full textFloßmann, Enrico. "Clinical and genetic epidemiology of stroke." Thesis, University of Oxford, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.441305.
Full textWan, Yize Isalina. "Genetic epidemiology of atopy and asthma." Thesis, University of Nottingham, 2011. http://eprints.nottingham.ac.uk/12224/.
Full textLubbe, Steven John. "The genetic epidemiology of colorectal cancer." Thesis, Institute of Cancer Research (University Of London), 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.538696.
Full textAl, Arrayed Shaikha Salim. "Epidemiology of genetic disease in Bahrain." Thesis, University of Aberdeen, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.259653.
Full textRoxburgh, Richard Hugh Stephen Richards. "The genetic epidemiology of multiple sclerosis." Thesis, University of Cambridge, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.614977.
Full textSvensson, Kerstin. "Genetic genealogy and epidemiology of Francisella." Doctoral thesis, Umeå universitet, Infektionssjukdomar, 2009. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-22452.
Full textDubé, Marie-Pierre. "New approaches in human genetic analysis." Thesis, McGill University, 1999. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=36581.
Full textThe second part addresses linkage-disequilibrium based fine mapping in the French Canadian population. The performance of five linkage-disequilibrium based fine-mapping methods is evaluated using French Canadian chromosomes with one of three diseases found in this population: oculopharyngeal muscular dystrophy (OPMD), hidrotic ectodermal dysplasia (HED), and sensorimotor polyneuropathy with or without agenesis of the corpus callosum (ACCPN). The gene for OPMD was recently mapped and cloned, allowing us to evaluate the performance of the methods with the OPMD results, and to make predictions about the ACCPN and HED putative gene positions. In addition, a new approach to linkage-disequilibrium based fine mapping is presented using FrenchCanadian ascending genealogies. The method involves two steps. First, the likely founding couple of a mutation-bearing chromosome is identified using a computerised randomisation statistic. Then, using a delete-d jackknife resampling scheme, the distribution of gene mapping estimates is calculated from the count of ancestral recombinants and ancestral meioses joining the identified founding couple to the disease gene carriers. Gene mapping estimates are calculated from each marker individually, and confidence intervals of the estimates are derived from the jackknife distributions. The method, when applied to French Canadian families with OPMD, successfully confirmed the localisation of PABP2 responsible for OPMD and performed better than other linkage disequilibrium-based mapping models.
Lambert, Deborah M. "The genetic epidemiology of hyperphenylalaninemia in Québec /." Thesis, McGill University, 1994. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=55505.
Full textCantelmo, Jill Love. "The genetic epidemiology of asthma and allergy." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.434855.
Full textFord, Deborah. "Genetic epidemiology of breast and ovarian cancer." Thesis, Institute of Cancer Research (University Of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.367527.
Full textGregory, Wendy L. "The genetic epidemiology of primary biliary cirrhosis." Thesis, University of Newcastle Upon Tyne, 1993. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.359212.
Full textEnnis, Sarah. "Genetic epidemiology of the fragile X region." Thesis, University of Southampton, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.273869.
Full textBolton, Kelly. "The genetic epidemiology of ovarian cancer survival." Thesis, University of Cambridge, 2012. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.610071.
Full textDunn, Steven J. "Genetic epidemiology and heterogeneity of Campylobacter spp." Thesis, Nottingham Trent University, 2017. http://irep.ntu.ac.uk/id/eprint/32176/.
Full textHudson, Julie. "Maternal Gene-Environment Effects: An Evaluation of Statistical Approaches to Detect Effects and an Investigation of the Effect of Violations of Model Assumptions." Thesis, Université d'Ottawa / University of Ottawa, 2019. http://hdl.handle.net/10393/39637.
Full textDavis, Patricia. "The molecular evolution and genetic epidemiology of lyssaviruses." Thesis, University of Oxford, 2005. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.433259.
Full textMahmoud, Medhat [Verfasser]. "Genetic epidemiology of bovine infectious diseases / Medhat Mahmoud." Gießen : Universitätsbibliothek, 2019. http://d-nb.info/1188195239/34.
Full textIshihara, Lianna Shizuko. "The genetic and environmental epidemiology of Parkinson's disease." Thesis, University of Cambridge, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.612856.
Full textDeshmukh, Harshal. "Genetic epidemiology studies of aspects of diabetic complications." Thesis, University of Dundee, 2014. https://discovery.dundee.ac.uk/en/studentTheses/bdbeee0f-7507-411f-914f-95a889afa6d0.
Full textMarcão, Ana Maria Lopes. "Arylsulfatase A : Genetic epidemiology and structure/ function studies." Doctoral thesis, Universidade do Porto. Reitoria, 2003. http://hdl.handle.net/10216/9650.
Full textBadin, Sevil. "Genetic epidemiology of allergy to beta-lactam antibiotics." Thesis, King's College London (University of London), 2017. https://kclpure.kcl.ac.uk/portal/en/theses/genetic-epidemiology-of-allergy-to-betalactam-antibiotics(c6571b05-3322-4662-88c4-88b300c96c9d).html.
Full textWolber, Lisa Eleni. "The genetic epidemiology of age-related hearing impairment." Thesis, King's College London (University of London), 2015. http://kclpure.kcl.ac.uk/portal/en/theses/the-genetic-epidemiology-of-agerelated-hearing-impairment(97622e04-21fe-4cc6-aee1-145bee728af5).html.
Full textMarcão, Ana Maria Lopes. "Arylsulfatase A : Genetic epidemiology and structure/ function studies." Tese, Universidade do Porto. Reitoria, 2003. http://hdl.handle.net/10216/9650.
Full textRisso, Davide <1989>. "Genetic Epidemiology of Taste Perception and Cigarette Use." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2017. http://amsdottorato.unibo.it/7902/1/PhD_Thesis_RissoDavide.pdf.
Full textShetty, Priya Bhatia. "Genetic Epidemiology of Hypertension in Populations: Applications of Modified Methods." Case Western Reserve University School of Graduate Studies / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=case1385562333.
Full textMiller, P. W. "The genetic epidemiology of tardive dyskinesia in Northern Ireland." Thesis, Queen's University Belfast, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.446126.
Full textGao, P. "Epidemiology of asthma and atopy : environmental and genetic factors." Thesis, Swansea University, 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.637026.
Full textLin, Xinyi (Cindy). "Statistical Methods for High-Dimensional Data in Genetic Epidemiology." Thesis, Harvard University, 2014. http://dissertations.umi.com/gsas.harvard:11326.
Full textLi, Qiao. "Data mining and statistical techniques applied to genetic epidemiology." Thesis, University of East Anglia, 2010. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.533716.
Full textBaksh, Mohamed Fazilluddeen. "Sequential tests of association with applications in genetic epidemiology." Thesis, University of Reading, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250735.
Full textHammond, Christopher John. "Genetic epidemiology of common eye diseases : a twin study." Thesis, University College London (University of London), 2001. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.272510.
Full textMitry, Danny. "Primary rhegmatogenous retinal detachment : clinical epidemiology and genetic aetiology." Thesis, University of Edinburgh, 2013. http://hdl.handle.net/1842/8923.
Full textTobin, Martin Damian. "The genetic epidemiology of blood pressure in human populations." Thesis, University of Leicester, 2004. http://hdl.handle.net/2381/30481.
Full textYonova-Doing, Ekaterina. "The genetic epidemiology and omics of age-related cataract." Thesis, King's College London (University of London), 2018. https://kclpure.kcl.ac.uk/portal/en/theses/the-genetic-epidemiology-and-omics-of-agerelated-cataract(ea655b39-6da1-45d4-866b-7b29dfa12a23).html.
Full textBurrows, Kimberley. "Molecular genetic epidemiology studies of quantitative nucleic acid markers." Thesis, University of Bristol, 2015. https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.761240.
Full textPorter, Daniel Edward. "Studies on the genetic epidemiology of heritable breast cancer." Thesis, University of Edinburgh, 1995. http://hdl.handle.net/1842/21467.
Full textProsser, Christiane. "Genetic surveillance and molecular epidemiology of human malaria parasites." Thesis, The University of Sydney, 2021. https://hdl.handle.net/2123/27226.
Full textFeizabadi, Mohammad Mehdi. "Genetic relationships, subspecific differentiation and molecular epidemiology of mycobacteria." Thesis, Feizabadi, Mohammad Mehdi (1996) Genetic relationships, subspecific differentiation and molecular epidemiology of mycobacteria. PhD thesis, Murdoch University, 1996. https://researchrepository.murdoch.edu.au/id/eprint/51843/.
Full textMcHenry, Michael Lyon. "Genomic and Co-Evolutionary Determinants of Clinical Severity in Active Tuberculosis Patients." Case Western Reserve University School of Graduate Studies / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=case1623754259445275.
Full textGoode, Ellen Lee. "Epidemiology of hereditary prostate cancer : genetic analysis of susceptibility loci incorporating clinical characteristics /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/10856.
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