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Books on the topic 'Gene transfer, viral genome'

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Author: Grafiati

Published: 9 March 2023

Last updated: 10 March 2023

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1

Leaf, Huang, Hung Mien-chie, and Wagner Ernst 1960-, eds. Non-viral vectors for gene therapy. 2nd ed. Amsterdam: Elsevier Academic Press, 2005.

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2

Viral vectors for gene therapy: Methods and protocols. New York: Humana Press, 2011.

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3

1963-, March Keith Leonard, ed. Gene transfer in the cardiovascular system: Experimental approaches and therapeutic implications. Boston: Kluwer Academic Publishers, 1997.

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4

A, Machida Curtis, ed. Viral vectors for gene therapy: Methods and protocols. Totowa, N.J: Humana Press, 2003.

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5

A, Machida Curtis, ed. Viral vectors for gene therapy: Methods and protocols. Totowa, N.J: Humana Press, 2003.

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6

A, Machida Curtis, ed. Viral vectors for gene therapy: Methods and protocols. Totowa, New Jersey: Humana Press, 2003.

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7

G, Kaplitt Michael, and During Matthew J, eds. Gene therapy of the central nervous system: From bench to bedside. Amsterdam: Academic Press, 2006.

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8

Brambilla, Riccardo. Viral vector approaches in neurobiology and brain diseases. New York: Humana Press, 2013.

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9

Joset, Françoise. Prokaryotic genetics: Genome organization, transfer, and plasticity. Oxford: Blackwell Scientific Publications, 1993.

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10

Principles of molecular virology. London: Academic Press, 1993.

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11

Principles of molecular virology. 4th ed. Amsterdam: Elsevier Academic Press, 2005.

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12

Principles of molecular virology. 2nd ed. San Diego: Academic Press, 1997.

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13

Principles of molecular virology. 4th ed. Amsterdam: Elsevier Academic Press, 2005.

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14

Fundamentals of molecular virology. Hoboken, NJ: Wiley, 2007.

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15

Principles of molecular virology. Burlington, Mass: Academic Press, 2012.

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16

C, Summers William, ed. Reconceiving the gene: Seymour Benzer's adventures in phage genetics. New Haven: Yale University Press, 2006.

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17

Schleef, Martin. Minicircle and Miniplasmid DNA Vectors: The Future of Non-Viral and Viral Gene Transfer. Wiley & Sons, Limited, John, 2013.

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18

Schleef, Martin. Minicircle and Miniplasmid DNA Vectors: The Future of Non-Viral and Viral Gene Transfer. Wiley & Sons, Incorporated, John, 2013.

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19

Schleef, Martin. Minicircle and Miniplasmid DNA Vectors: The Future of Non-Viral and Viral Gene Transfer. Wiley & Sons, Incorporated, John, 2013.

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20

Schleef, Martin. Minicircle and Miniplasmid DNA Vectors: The Future of Non-Viral and Viral Gene Transfer. Wiley & Sons, Incorporated, John, 2013.

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21

(Editor), Kazunari Taira, Kazunori Kataoka (Editor), and Takuro Niidome (Editor), eds. Non-viral Gene Therapy: Gene Design and Delivery. Springer, 2005.

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22

Machida, Curtis A. Viral Vectors for Gene Therapy: Methods and Protocols. Humana Press, 2010.

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23

Viral Vectors for Gene Therapy: Methods and Protocols. Humana, 2019.

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24

Al-Rubeai, Mohamed, and Otto-Wilhelm Merten. Viral Vectors for Gene Therapy: Methods and Protocols. Humana Press, 2016.

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25

Perkins, Archibald Simon. The development of retrovirus-derived vectors for gene transfer in mammalian cells. 1987.

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26

Gene Transfer in Cardiovascular System: Experimental Approaches & Therapeutic Implications (Developments in Cardiovascular Medicine). Springer, 1997.

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27

Minicircle And Miniplasmid Dna Vectors The Future Of Nonviral And Viral Gene Transfer. Wiley-VCH Verlag GmbH, 2012.

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28

Machida, Curtis A. Viral Vectors for Gene Therapy: Methods and Protocols (Methods in Molecular Medicine). Humana Press, 2002.

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29

Gene Therapy of the Central Nervous System: From Bench to Bedside. Academic Press, 2005.

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30

Gene therapy in the central nervous system: From bench to bedside. San Diego, CA: Elsevier/Academic Press, 2006.

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31

Monteggia, Lisa M., and Wei Xu. Methods for In Vivo Gene Manipulation. Edited by Dennis S. Charney, Eric J. Nestler, Pamela Sklar, and Joseph D. Buxbaum. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190681425.003.0004.

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Recent advances in mouse genetics have opened many new avenues of research in which to explore gene function in the brain, and contributions to the pathophysiology and treatment of psychiatric disorders. The use of the mouse to explore gene function has contributed a better understanding of the role of specific genes in the nervous system including their influence on neural circuits and complex behavior.This chapter explores current approaches to manipulate gene function in a mouse. Genetically modified mice allow for the investigation of a particular gene in vivo. The approaches discussed highlight recent advances to specifically overexpress or disrupt a specific gene of interest in the brain. We also highlight viral-mediated gene transfer approaches to allow for spatial and temporal control of gene function.

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32

Brambilla, Riccardo. Viral Vector Approaches in Neurobiology and Brain Diseases. Humana Press, 2016.

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33

Heiser, William C. Gene Delivery to Mammalian Cells : Volume 2: Viral Gene Transfer Techniques. Humana Press, 2010.

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34

Thursfield, Rebecca, Chris Orchard, Rosanna Featherstone, and Jane C. Davies. Future treatments. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780198702948.003.0013.

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There are only a relatively limited armoury of drugs, the majority of which are aimed at downstream symptoms of cystic fibrosis. Therapies targeting the basic defect in CF as well as continued availability of more conventional drugs are required. Progress in gene therapy has been limited by the significant barriers to gene transfer of the CF lung, but the UK is hosting a large repeated dose trial of nebulized non-viral gene therapy designed around clinically meaningful outcomes. The UK CF Gene Therapy Consortium is also seeking to develop a promising modified lentiviral approach, although this is some years off. Perhaps the exciting development of recent decades has come from small molecule CFTR modulators, driven by an understanding of basic pathophysiological mechanisms. Ivacaftor is the first drug to be licensed, having proved itself highly clinically efficacious in patients with the class-3 gating mutation G551D. The trial pipeline seeks to expand indications for this and to explore the potential of Phe508del correctors. Finally, a number of anti-inflammatory and anti-infective strategies are being pursued. The emerging global problem of antibiotic resistance is leading to exciting alternatives such as biofilm disruption and bacteriophage to be explored.

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35

Heiser, William C. Gene Delivery to Mammalian Cells: Volume 2: Viral Gene Transfer Techniques (Methods in Molecular Biology). Humana Press, 2003.

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36

High, Katherine, and Roland W. Herzog, eds. Approaches to Blocking the Immune Response to Gene Transfer with Viral Vectors. Frontiers Media SA, 2012. http://dx.doi.org/10.3389/978-2-88919-055-3.

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37

Summers, William C., and Frederic Lawrence Holmes. Reconceiving the Gene: Seymour Benzer's Adventures in Phage Genetics. Yale University Press, 2010.

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38

Summers, William C., and Frederic Lawrence Holmes. Reconceiving the Gene: Seymour Benzer's Adventures in Phage Genetics. Yale University Press, 2008.

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39

Parsonson, Ian. Australian Ark. CSIRO Publishing, 1998. http://dx.doi.org/10.1071/9780643100688.

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This definitive work on the introduction of domestic animals to Australia begins with the first white settlement at Botany Bay. It explores the foundations of our wool and beef industries, examining the role of early leaders like Phillip, King, Macarthur and Bligh.The book considers the successful introduction of the horse, Australia's first live animal export, and goes on to explore the role of the acclimatisation societies, the development of the veterinary profession and the control and eradication of some of the major exotic and introduced diseases of sheep and cattle. The author, Dr Ian Parsonson, retired as Assistant Chief of the Australian Animal Health Laboratory at Geelong, Victoria, after a long career in veterinary practice and research. His areas of expertise include bacterial and viral diseases, pathology and microbiological laboratory safety. He is a committee member of the International Embryo Transfer Society and the Animal Gene Storage and Resource Centre of Australia.

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40

Principles of Molecular Virology, Student edition with CD -ROM. 3rd ed. Academic Press, 2001.

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41

Isaac, Allan Punzalan. Filipino Time. Fordham University Press, 2021. http://dx.doi.org/10.5422/fordham/9780823298525.001.0001.

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Filipino Time examines how a variety of immaterial labor performed by Filipinos in the Philippines and around the world, while producing bodily and affective disciplines and dislocations, also generate and explore vital affects, multiple networks, and other worlds. Whether in representations of death in a musical or keeping work time at bay in a call center, these forms of living emerge from and even work alongside capitalist exploitation of affective labor. Affective labor involves human intersubjective interaction and creative capacities. Thus, through creative labor, subjects make communal worlds out of one colonized by capital time. In reading these cultural productions, the book traces concurrent chronicities, ways of sensing and making sense of time alongside capital’s dominant narrative. From the hostile but habitable textures of labor-time, migratory subjects live and weave narratives of place and belonging, produce new modes of connections and ways to feel time with others.The book explores how these chronicities are re-articulated in a capacious archive of storytelling about the Filipino labor diaspora in fiction, in a musical, in an ethnography, and in a documentary film. Each of the genres demonstrates how time and space are manifest in deformations by narrative and genre. These cultural expressions capture life-making capacities within the capitalist world of disruptions and circulations of bodies and time. Thus, they index how selves go out of bounds beyond the economic contract to transform, even momentarily, self, others, time, and their surroundings.

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42

Vaheri, Antti, James N. Mills, Christina F. Spiropoulou, and Brian Hjelle. Hantaviruses. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780198570028.003.0035.

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Hantaviruses (genus Hantavirus, family Bunyaviridae) are rodent- and insectivore-borne zoonotic viruses. Several hantaviruses are human pathogens, some with 10-35% mortality, and cause two diseases: hemorrhagic fever with renal syndrome (HFRS) in Eurasia, and hantavirus cardiopulmonary syndrome (HCPS) in the Americas. Hantaviruses are enveloped and have a three-segmented, single-stranded, negative-sense RNA genome. The L gene encodes an RNA-dependent RNA polymerase, the M gene encodes two glycoproteins (Gn and Gc), and the S gene encodes a nucleocapsid protein. In addition, the S genes of some hantaviruses have an NSs open reading frame that can act as an interferon antagonist. Similarities between phylogenies have suggested ancient codivergence of the viruses and their hosts to many authors, but increasing evidence for frequent, recent host switching and local adaptation has led to questioning of this model. Infected rodents establish persistent infections with little or no effect on the host. Humans are infected from aerosols of rodent excreta, direct contact of broken skin or mucous membranes with infectious virus, or rodent bite. One hantavirus, Andes virus, is unique in that it is known to be transmitted from person-to-person. HFRS and HCPS, although primarily affecting kidneys and lungs, respectively, share a number of clinical features, such as capillary leakage, TNF-, and thrombocytopenia; notably, hemorrhages and alterations in renal function also occur in HCPS and cardiac and pulmonary involvement are not rare in HFRS. Of the four structural proteins, both in humoral and cellular immunity, the nucleocapsid protein appears to be the principal immunogen. Cytotoxic T-lymphocyte responses are seen in both HFRS and HCPS and may be important for both protective immunity and pathogenesis. Diagnosis is mainly based on detection of IgM antibodies although viral RNA (vRNA) may be readily, although not invariably, detected in blood, urine and saliva. For sero/genotyping neutralization tests/RNA sequencing are required. Formalin-inactivated vaccines have been widely used in China and Korea but not outside Asia. Hantaviruses are prime examples of emerging and re-emerging infections and, given the limited number of rodents and insectivores thus far studied, it is likely that many new hantaviruses will be detected in the near future.

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43

Kirchman, David L. Genomes and meta-omics for microbes. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780198789406.003.0005.

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The sequencing of entire genomes of microbes grown in pure cultures is now routine. The sequence data from cultivated microbes have provided insights into these microbes and their uncultivated relatives. Sequencing studies have found that bacterial genomes range from 0.18 Mb (intracellular symbiont) to 13 Mb (a soil bacterium), whereas genomes of eukaryotes are much bigger. Genomes from eukaryotes and prokaryotes are organized quite differently. While bacteria and their small genomes often grow faster than eukaryotes, there is no correlation between genome size and growth rates among the bacteria examined so far. Genomic studies have also highlighted the importance of genes exchanged (“horizontal gene transfer”) between organisms, seemingly unrelated, as defined by rRNA gene sequences. Microbial ecologists use metagenomics to sequence all microbes in a community. This approach has revealed unsuspected physiological processes in microbes, such as the occurrence of a light-driven proton pump, rhodopsin, in bacteria (dubbed proteorhodopsin). Genomes from single cells isolated by flow cytometry have also provided insights about the ecophysiology of both bacteria and protists. Oligotrophic bacteria have streamlined genomes, which are usually small but with a high fraction of genomic material devoted to protein-encoding genes, and few transcriptional control mechanisms. The study of all transcripts from a natural community, metatranscriptomics, has been informative about the response of eukaryotes as well as bacteria to changing environmental conditions.

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